From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Sent: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc:Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From : Muniz, Maria de Los Angeles <@vitalant.org> Se nt : Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject : National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Sent: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global <@gl oba ldownsynd rome.org> Sent: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk <@globaldownsyndrome .org>; Marisa Cucuzzella <@ajsfoundation .com>; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Sent : To : Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Sent: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Sent: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From : (b)(6) Sent : Wednesday, March 4, 2020 5:46 PM To : Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject : Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To : Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Sent: (b)(6) From: Aliantha Angel (b)(6) Sent: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject : Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Sent: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From:Gordon, Joshua (N IH/NIMH) [El Sent : Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject : Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.<@abc.com> Sent: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject : Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Sent: To : Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From:RichSilverman Sent: Wednesday,March 4, 2020 8:56 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To : Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Sent: Wednesday, Marc h 4, 2020 6:59 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Sent: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject : Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Sent: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From:Steve Black Sent: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen <@cepi.net> Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Sent : Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To : Subject : Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park <@time.com> Sent : Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject : TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Sent : To : Subject : (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To : Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Sent: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From : Fauci, Anthony (NIH/NIAID) [E] Sent : Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject : RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Sent: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Sent: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Sent : Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Sent: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject : FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From : Johnson, Christie <@turne r.co m> Sent : Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject : Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From : Johnson, Christie Se nt: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject : CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@t urner .com > Sent: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Sent : Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject : CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From : KUMAR SHAH, MD (b)(6)> Sent : Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject : Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To : Siegel, Marc Subject : RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc <@nyulangone.org> Sent: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser <@patientsafetymovement .org> Sent : Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay <@patientsafetymovemen t .org> Subject : COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Se nt : Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To : Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject : How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Se nt : Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Sent : Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject : my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Sent : Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject : Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Dat e: March 3, 2020 at 1:35:53 PM EST To: SHOC <@who.int>, "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) <@resolvetosavelives.org>, , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Se nt: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subje ct : Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Sent: (b)(6) To : Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey <@jesuits .org> Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : expand@omcasa .com <@omcasa .com> Sent : Tuesday, March 3, 2020 5:00 AM To : Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Sent : To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From : El Bcheraoui, Charbel Se nt: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subjec t: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Sent: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Sent: To: Subject : Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From : Lily Carnie (b) ( Sent: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Sent: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject : Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Sent : To: Subject : Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Se nt: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) <@sky.uk> Sent : Tuesday, March 3, 2020 6 :16 AM To : Fauci, Anthony (NIH/NIAID) [El Subj ect : Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Sent : Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Sent: To : Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Sent : To: Subject : I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Sent: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" <@wsj .com > Date : Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject : Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Sent : To: Subject : hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Sent: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subj ect : Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date : March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Sent: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Sent: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Sent: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Sent: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject : Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi <@wsj.com> Sent : Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject :? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Sent: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan <@cbsnews.com > ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Sent : (b)(6) To : Subject : Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay <@pitt.edu >wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay <@pitt.edu>wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Sent : (b)(6) To : Subject : Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Sent : Mon, 2 Mar 2020 10:43:27 +0000 To : Marston, Hilary (NIH/NIAID) [El Subject : FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From:Amel ie RIOUX Sent: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Sent : Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Sent : To: Cc: (NIH/NIAID) [El Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Sent : Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject : Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Sent : Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject : Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Sen t: Sunday, March 1, 2020 2:46 PM -----~ ~ To : Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date : Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject : Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick <@statnews .com> Sent : Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject : Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Sent : Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From : Sent : Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To : ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : pascal goldschmidt __________ Sent : Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subj ect : (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Silverberg, Kristen <@brt.org> Sent: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Sent: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Sent: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Sent : Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject : Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi update: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi update: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Sent: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari <@scripps.edu> Sent: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST<@utsouthwestern .edu>; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone <@scripps.edu>; Eckard Wimmer <@stonybrook.edu> Cc: Charles Rice <@scripps.edu> Subject : (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Sent : Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject : SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily <@americanchemistry .com> Sent: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From:Thomas Murray Sent: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Sent : To: Subject : You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Sent : Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Corey MD, Larry _______ Sent: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To : Subject : Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Sent: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From:Jeffrey V. Ravetch Sent : Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject : Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Sent: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject : (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sun, 1 Mar 2020 19:22:37 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Jim Iversen (b)(6) Sent: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Sent : Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To : Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Sent: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc:Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From:Sharon Eblen sent: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Sent: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To : Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai <@npr.org> Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai <@npr .org> Sent: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc:Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai <@npr .org> Sent: Thursday, February 27, 2020 2:09 PM To : Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Se nt : Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject : Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From : "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Sent: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Sent: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From:Bob Franken-------~ (b-)~(6) => > Sent: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From:Collins, Francis (NIH/OD) [El Sent: Wednesday, Febru ary 26, 20 20 7:59 AM To : M ichael Milken (mm ilken@knowledgeu .com) <@knowledgeu .com> Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From : Conrad, Patricia (NIH/NIAID) [E) Se nt: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject : Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From : "Blackburn, Amy (NIH/OD) [El" Date : February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject : RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Sent: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. <@fhn.org> Sent: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Sent : Thursday, February 27, 2020 9:07 AM -------------- To : Fauci, Anthony {NIH/NIAID) [E] Subj ec t : ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From : Winnie Stachelberg <@americanprogress.org> Sent: Thursday, February 27, 2020 8:02 AM --------, To : Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject : RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From : Winnie Stachelberg Sent : Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject : FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From : Steve Bonitatibus <@americanprogress.org > Se nt : Thursday, August 15, 2019 11:21 AM To: Posted Products <@ame ricanp rogress.org> Cc: Kyle Epstein <@ame ricanprogress.org>; Daniella NIH-001111 Leger <@americanprogress.org > Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From:Howard Schatz Sent : Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject : Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik <@npr.org > Sent: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Sent: To: Subject : Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Sent: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To : Subject : That number seems exceptionally high. From: Strauss, Eric M . <@abc .com> Se nt : Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Se nt: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Sent : To: Subject: Let us discuss. From : Sabrina Ma lhi <@thehill .com> Sent: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi <@t hehi ll.com > Sent: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Sent : To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Sent : Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subjec t : Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From : Barry Coller (b)(6)> Date : February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc : Barry Coller ----------- (b)(6) Subje ct : Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From:Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen <@brook ings.edu> Sent: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim <@brookings.edu> Subject : Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Sent: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Sent: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject : RE: Sent: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : B arton Haynes , M.D. Sent: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Sent : Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Sent: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From : Barton Haynes , M.D. Sent: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject : RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Sent: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Sent: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Sent: Saturday, February 29, 2020 11:03 AM To : -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject : Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To : Subject : RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Sent : Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject : in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Fred Schaich <@ifaratv.org > Sent: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Sent: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Sent: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Sent : To: Subject : Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Sent : Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Sent: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Les Gardonyi (b)(6)> Sent: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject : Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Sent: Sat, 29 Feb 2020 23:54:27 +0000 To : Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Sent: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu <@protherimmune.com> Sent: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang <@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subjec t: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From : Tom Leopold (b) (6) Sent : Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From : Tom Leopold (b) ( Sent: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman <@ohsu .edu> Sent : Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Se nt: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To : Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject : Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Sent: To: Subject : (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From:Tabak, Lawre nce (NIH/OD) [El Sent: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc:Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From : Samant ha Mauro ------------- (b)( 6)> Sent: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject : Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Sent: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" <@cdc.gov> , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Sent : To: Subj ect : ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Gere diZerega Sent : Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subj ect : Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Sent: (b)(6) To : Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan <@theatlantic.com> Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Sent: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander <@rttv.ru> Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Sent: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subje ct: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Sent: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From : Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From : Allison Ogdon <@keystonesymposia.org> Sent: Friday, February 28, 2020 12:10 AM To : Allison Ogdon <@keystonesymposia.org> Cc: Heidi Daetwyler <@keystonesymposia .org> Subject : Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From:Kline, Lydia (NIH/OD) [El CbH6J> Sent : Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Sent: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Sent : Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc : Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From : Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject : Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Sent: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject : Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Sent: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From:Jose Alcami Pertejo <@isciii .es> Sent: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc:Jose Alcami Pertejo <@isciii.es> Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From:Conrad, Patricia (NIH/NIAID) [El Sent: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady <@economicclub.org> Sent: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza <@economicclub.org> Subject : David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Se nt: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Se nt: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Sent: To: Subject: FYI. Does this deserve a response. From:Nejat Duzgunes (b) (6) Sent: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Sent : Thursday, February 27, 2020 2:03 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject : RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Sent : To : Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments <@hms.harvard.edu> Sent : Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara <@hms .harvard .edu>; Tekleab, Sarah <@hms.harvard .edu> Subject : Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Sent : To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai <@npr .org> Se nt: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject : Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Sent: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc:Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject : FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Sent : Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Sent: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Sent: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subj ect: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Sent: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra <@abc.com> Sent: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Sent: To : Cc: Subject : Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park <@time.com> Sent : Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject : Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park <@t ime.com> wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject : RE:URGENT Sent: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Sent: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Se nt : Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David <@aaaai.org>; Rebecca Brandt (AAAAI) <@aaaai.org> Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Sent : To: Subject : Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie <@nas.edu> Sent: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject : Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From : Jon Coh en <@aaas.org> Sent: Thursday, February 27. 2020 5:48 PM To : Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Sent: To : Cc: Subject : by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Sent: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" <@spglobal.com> Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" <@niaid.nih.gov>, "My les, Renate (NIH/OD) [E]" (b)(6) Subject : Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Sent : Thursday, February 27, 2020 6:55 PM To: Young, Donna <@spglobal. com> Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject : Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" <@spglo bal.com > Date : Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" <@niaid .nih .gov>, "My les, Renate (NIH/OD) [E]" (b)(6)> Subject : Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Sent: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna <@spg loba l.com > Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" <@spg loba l.com > Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Sent: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih .gov>; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To : Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Sent: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Sent : Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject : _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Sent : (b)(6) To : Subject : Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To : "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia <@imf.org> On Behalf Of Gopinath, Gita Sent : Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita <@imf.org>; Milesi -Ferretti, Gian Maria ; Celasun, Oya <@imf .org>; Christiansen, Lone Engbo <@imf.org> Subject : Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject : Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Sent : Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC <@who .int>; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject : The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Sent: To: Subject : FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) <@m snbc.com > Sent: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) <@msn bc.com > > Sent: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject : Please set this up. Thanks. From:Fox, Lauren <@turner .com> Sent: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject : Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Sent : To : Subject : Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Se nt: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject : My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James <@wsj.com> Sent : Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject : Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Sent: To: (NIH/NIAID) [E] (b)(5) Thanks . From:Marston, Hilary (NIH/NIAID) [E] (b)(6)> Sent: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" <@hhs.gov> Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To : Subject : 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Sent: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Sent: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Sent : To : Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Se nt: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject : RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Sent : Monday, March 2, 2020 8:14 PM -------=-=-=- To : Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject : Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From : "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject : RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Sent : Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject : Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc:"Stee le, Danielle (HHS/10S)" ---------Subje ct: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Sent : Thursday, February 20, 2020 12:19 PM To : Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject : Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Sent: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject : FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Sent : To : Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Se nt: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject : RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Se nt: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Sent: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Sun, 1 Mar 2020 22:35:38 +0000 To : Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Sent: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Sent: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Sent: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To : Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Sent : Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Sent: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Sent : To : Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) sent: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject : Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Sent: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Sent: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject : mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject : RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Se nt: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject : FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From : Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Sent : Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Sent : To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Sent: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Sent: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Sent: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Sent: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From : Laura Landerman-Garber Sent : Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject : Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Sent: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " <@nia id.nih.gov > Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From : Sent : To: Subject : Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From : LOUIS FORTUNATO Sent : Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject : Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject : Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date : February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From : LOUIS FORTUNATO (b)(6)> Subject : HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date : November 3, 2019 at 5:11:19 AM EST To : (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Sent: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Sent: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" <@wtop .com > Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" <@wtop.com > Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Sent: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To : Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" <@wtop.com > Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From:Anderson, Liz Sent: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura <@wtop.com> Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Sent: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett <@nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Sent : To : Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject : RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth <@nejm .org> Sent : Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject : RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Sent : Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth <@nejm.org> ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject : RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth <@nejm .org > Sent: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Sent: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org > Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject : RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth <@nejm.org > Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subj ect : NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Sent: To : Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams <@nationalpress.org> Sent : Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Sent : (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth <@nejm.org> Se nt : Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject : RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From : Laurencot, Elizabeth Sent: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject : RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Sent: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth <@ne jm .org> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject : RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org > Sent : Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject : NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Sent : To : Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Sent : Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti <@bbc.co .uk> Sent : Wednesday, February 26, 2020 11 :47 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject : RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Sent : Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject : Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Shannon Williams <@sibf.org> Sent: Wednesday, February 26, 2020 11:10 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) <@nbcuni.com> Sent : Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject : MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Sent : To: Subject : See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth <@nejm.org> Sent : Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject : RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Se nt: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org> NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject : RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org> Sent : Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Sent : Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject : First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Sent: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To : --------- Cc: Subject : I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Sent: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : Fro m: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Sent : To: Cc: (NIH/NIAID) [El Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Sent : Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject : FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Sent : (b)(6) To : Subject : Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To : Tom Frieden (b)(6) Subject : A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Sent: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Sent: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Sent: Wed, 26 Feb 2020 10:59:30 +0000 To : *'@ ~ Subject : RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ <@thepaper.cn> Sent: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Sent: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" <@turner .com > Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From : Jon LaPook ,,;::;... ---~ (b ~)~(= > Sent: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Sent: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To : Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G <@nytimes.com>w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Sent: (b)(6) To : Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton <@theasiagroup.com> Sent : Tuesday, February 25, 2020 10:59 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Sent: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" <@msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Sent: (b)(6) To : Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) <@tum er.com >wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" <@turner.com> Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) <@turner .com> Sent: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Sent: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike <@wtop.com> Sent : Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Sent: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject : Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Sent : (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Sent : Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject : RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Sent: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Sent: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" <@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" <@siriusxm.com> Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To : Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject : RE: Coronavirus vaccine From : Sent: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> sent: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Sent : To: Subject : variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Sent : Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject : Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Laurencot, Elizabeth <@nejm.org> Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To : Subject : Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Sent : Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks <@resolvetosavelives.org> __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC<@who .int>; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject : The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" <@b loomberg .net> Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" <@nia id.nih.gov> Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" <@bloomberg.net> Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley <@bdo.com> Sent: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota <@bdo.com> Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Sent: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Sent: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Sent : Monday, February 24, 2020 6:03 PM ------------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Sent: To : Subject : COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Dweck, Kristen <@hsph.harvard .edu> Sent : Monday, February 24, 2020 5:34 PM To : Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject : Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From : Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Sent : To: Subj ect : W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Sent : Monday, February 24, 2020 4:04 PM To : Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject : RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 F r o m: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subjec t : RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@b loombe rg.net> Sent: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From : Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloom berg .net> Sent: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To : JASON GALE CC: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloo mberg .net > Sent: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] <@nih.gov> Cc: Routh, Jennifer (NIH/NIAID) [E] <@nih .gov > Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From : 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloombe rg.net> Sent: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net> Sent: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From : (b)(6) At: 01/17/20 03 : 22 : 49 To : Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc : (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) <@b loo m berg . net > Sent: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloomb erg . n e t > NIH-001410 Sent: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 F rom : )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To : Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subj e ct : Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Sent: To: Subject : NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From : DANIEL GAGNON Sent: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Sent : To: Subject : Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI <@nytimes.com> Sent : Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Sent : To: Subject : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Se nt: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subjec t : ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked to: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Sent : To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Sent: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Sent : To : Subject : You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Sent : Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject : ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To : Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject : RE: Interview Request from China From: Sent : Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Faye Li (b)(6)> Se nt: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Sent: Monday, February 24, 2020 10:46 AM To : Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject : FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Sent: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Sent: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine <@ma nuscriptcentral. com> Sent : Monday,Febrnary 24, 2020 10:00 AM To : Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subj ect: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subjec t: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Sent: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc : Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Sent : To : Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Sent : Monday, February 24, 2020 8:54 AM To : Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc : Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Sent : Monday, February 24, 2020 6:45:07 AM To : Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc : Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject : RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From : Myles, Renate (NIH/OD) [E] (b)( Se nt: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject : RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From : Fauci, Anthony (NIH/N IAID) [E] ______ Sent : Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Sent: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc : Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Sent: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Sent: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net > Sent: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subje ct: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From : John Lauerma n (BLOOMBERG/ NEWSROOM:) <@b loomberg.net> Sent: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject : Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject : FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Sent: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Sent: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject : Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date : February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Sent : Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Sent : Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Se nt: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subj ect : RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Gatti, Philip (b)(6) Sent: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Tabak, Lawrence (NIH/OD) [E] (b)(6) Sent : Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject : Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From : Fauci, Anthony (NIH/N IAID) [El (b)(6) Sent : Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . Fro m : Tabak, Lawrence (NIH/OD) [El Sent: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject : Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Sent: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Sent: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Wed, 26 Feb 2020 18:25:04 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Sent : Wednesday, February 26, 2020 1:12 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From : Brennan, Patrick (05/ASPA) Sent : Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc : ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject : For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject : Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From : "Brennan, Patr ick (OS/ASPA)" Date : Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" <@hhs.gov>, "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Sent: To: Subject : Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Sent: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Sent : To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Sent: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject : Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Dat e: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" <@hhs.gov >, "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From : Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Se nt : Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date : Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From : Kadlec, Robert (OS/ASPR/I0 ) Se nt: Monday, February 24, 2020 10:19 PM To : Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject : 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From : Moughalian, Jen (HHS/ASFR) Sent : Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject : RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From : Fauci, Anthony {NIH/N IAID) [El (b) ( > Se nt: Monday, February 24, 2020 1:42 PM To : Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Sent : Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Sent: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih .gov > Sent: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] <@mail.nih.gov >; Collins, Francis (NIH/OD) [E] <@nih .gov>; Gilman, James (NIH/CC/OD) [El <@n ih.gov > Cc: Burklow, John (NIH/OD) [E) <@od .nih .gov >; Hallett , Adrienne (NIH/OD) [E) <@nih.gov >; Billet, Courtney (NIH/NIAID) [E) <@nia id .nih .gov>; Davey, Richard {NIH/NIAID) [E] <@cc.nih.gov >; Cohen, Justin {NIH/CC/OD) [El <@nih .gov > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Sent: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject : FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject : Please handle. ---------------- From: Sent : Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Sent: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Sent: To : Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Jon LaPook ,,;:;-----~ (b~)~(6) = Sent: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From:Jon LaPook ,.:::;...----. (b ~)~(6) = Sent: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Sent: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Sent: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sun, 23 Feb 2020 15:56:48 +0000 To : Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Sent: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From : john won (b) (6) > Sent: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Sent: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subje ct: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From:Julia Belluz <@vox.com> Sent : Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject : Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz <@vox.com > wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Sent : Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subjec t : Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Sent: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Sent : Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject : FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Sent : Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Se nt: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Sent: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Sent: To : Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Sent: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject : RE: interview request: draft responses for Greek newspaper From: Sent: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Sent : Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG <@niaid.nih.gov > Cc: NIAID COGCORE<@niai d.nih .gov> Subject : int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From : Sent : To : Subj ect : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From : Cassett i, Cristina (NIH/NIAID) [El Sent : Saturday, February 22, 2020 2:26 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject : Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject : HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From : Sent : To: Subject : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Cassetti , Cristina (NIH/N IAID) (E] ---------Sent : Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject : Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date : February 18, 2020 at 3:07:21 PM EST Subject : HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Sent : To : Subject : Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Se nt : Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject : Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Sent: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Sent: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Sent: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From : Schneider, Johanna (NIH/NIAID) [El Se nt : Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject : For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Sent: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject : Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To : Cc: Subject : Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci <@businesscouncil.com> Sent : Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject : Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----Fr om: JF K (b) (6) Sent : Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Sent : To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen <@iasusa .org> Se nt: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen <@iasusa .org>; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject : RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Sent : Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen <@iasusa .org >; Barie, Toni C _________ _ <@iasusa.org >; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject : Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane <@:.. ____ (b) (b)(6) (b _ )_(_. 6>;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" <@t..,_____ Cb _)_@ ... wrote: Dear Ken, The (b) (6) . Committee greatly appreciatesyour willingnessto approach Dr. Anthony Fauci on our behalf, asking him to address the residents of the----,---, (b) (6) on the Coronavirus. It would perhaps be hel ful to Dr.Fauci, to ex lain who we are and what we do. (b) ( , (b)(6) The (b) ( Committee was ormed recently to create and orgamze events to e ucate, enlighten and entertain members of the Somerset community.A few weeks ago (b)(6) spoke to a sold out crowd on impeachment. We've featured authors on a variety of topics; invited doctors with specialtiesof interest to our communityorganized trips to the KennedyCenter and theaters for attendanceat ballets and plays and sponsored visits, led by experts, to various museums and the Library of Congress to view special exhibitions. An example of the latter is a tour of the Folger Library (b) (6). A presentationby Dr. Fauci on the coronaviruswould be of great interest to our constituencywho keep informed by reading both national and internationaljournals. We are flexible on the date for such an appearanceneeding only a few days' notice to inform our residents. I need not tell you that it wou ld our great honor to welcome Dr. Fauci to the NIH-001660 (b) (6):. Sincerely (b)(6) NIH-00166 1 From: Sent : To : Cc: Subject : Eastern Daylight Time I totally agree. Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 12:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E) Marston, Hilary (NIH/NIAID) [E);Barasch, Kimber ly (NIH/NIAID) [CJ RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM I do not want to be on a "session planning" call. Please have Hilary do this as suggested by Patty since she is preparing t he talk . T hanks. From: Conrad, Patricia (NIH/NIAID) [E) Sent : Friday, February 21, 2020 4:44 PM To : Folkers, Greg (NIH/NIAID) [E] (b)( 6) ---------------~~ --------- (b)(6) (b)(6Jr>;Fauci, Anthony (NIH/NIAID) [El Subject : FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Sent : Friday, February 21, 2020 4:37 PM To : Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Sent : Friday, February 21, 2020 6:14 PM To : Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject : DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Sent : To : Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From:Garen, Alan (b)( > Sent: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From:Antoniak, Cynthia {NBCUniversal, MSNBC) <@MSNBC.COM> Sent: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) <@nbcuni.com>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Sent : Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From:Antoniak, Cynt hia (NBCUniversal, MSNBC) <@MSNBC.CO M > Sent : Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Sent: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM >; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Sent: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Sent: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@M SNBC.COM > Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent : Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject : [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) <@nbcuni.com > Sent : Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject : RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent : Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject : [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Sent: Friday, February 21, 2020 10:29 AM To : Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From : Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject : CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Goldner, Shannah (NBCUniversal) <@nbcuni.com > Sent : Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject : RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From : Conrad, Patricia (NIH/NIAID) [E) Sent : Thursday, February 20, 2020 4 :16---------- (b)( PM To : Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject : [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Sent: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject : hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject : Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" <@MSNBC.COM> Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" <@nbcun i.com>, "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject : MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@n bcuni.com> Sent: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc:Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject : [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc:Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Sent: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject : [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject : RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Sent: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject : [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Sent: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject : FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Sent: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Sent: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Sent : (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From : Billet, Courtney (NIH/NIAID) [E] Sent: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject : RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Sent: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject : Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Sent : To: Cc: Subjec t: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Sent: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Sent: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Sent: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie <@iasusa .org> Subject : RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Sent: Tuesday, February 18, 2020 8:09 PM To : Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen <@iasusa .org> Subject : RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Sent : To : Subject : Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Sent : Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject : FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Sent : To : Subject : Attac hment s: Pleasehandle. From : RICK SAWAYA (b)(6)> Sent : Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject : Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject : Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Sent : To: Subject : Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen <@iasusa.org> Se nt: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject : RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From : Fauci, Anthony (NIH/N IAID) [E] Sent : Thursday, February 20, 2020 7:12 AM To : Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie <@iasusa.org> Subject : RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Sent : Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen <@iasusa.org> Subject : RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From : McNei l Jr, Donald G <@nytimes.com> Sent : Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G <@nyt imes.com> wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Sent : Thursday, February 20, 2020 6:57 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang <@caixin.com> Sent : Thursday, February 20, 2020 3:16 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject : Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Achenbach, Joel <@washpost.com> Sent: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel <@washpost.com> Subject : RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost Sent: Thu rsday, February 20, 2020 5:51 PM .com > NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject : quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Sent: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Sent: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } <@niaid.nih.gov> Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Sent: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Sent : Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject : GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Sent : To: Subject : Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From:Sharon Rockefeller <@we ta.org> Sent : Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Thu, 20 Feb 2020 00:54:10 +0000 To : Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Sent: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman <@biocentury .com> Sent : Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Sent: To: Cc: Subject : Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Crow, Hilary <@USChamber.com> Sent: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Sent: To : Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Marston, Hilary (NIH/NIAID) [E] (b)(6)> Sent : Wednesday, February 19, 2020 10:09 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject : Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM <@niaid .nih.gov > Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From : Feng Zhao <@wor ldbank.org > Sent: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla <@worldbank .org>; Rocio Schmunis <@worldbank .o rg>; Gabrielle Lynn Williams <@worldban k.org>; Muhammad Ali Pate <@worldba nk.org> Subject : Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Sent : To: Subject : Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Sent: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc : Andrew (b) (6J> Turl ey (b)(6)> Subject : Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall <@scgcorp.com> Sent: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM <@n iaid. n i h.gov>; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria <@scgcorp.com>; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa <@scgcorp.com>; Megan Schartner <@scgcorp .com> Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention <@crit icalment ion .com> Sent: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To : bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject : RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From : Br iana Doherty <@manu scriptcentral.com > Sent : Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Sent: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Sent: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Sent : Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To : Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject : FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Sent : Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject : Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From : Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM <@niaid.nih .gov> Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen <@iasusa.org > Date : February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ <@iasusa.org > Subject : RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Sent: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon <@aacr.org> Sent: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To : Subject : Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine <@manuscriptcentral.com> Sent: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Sent: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Sent: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Sent: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <@o d. ni h.gov> Cc: NIAID COGCORE<@niaid .nih .gov> Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subjec t: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Sent: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc : Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Sent: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc:Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg <@mail.nih .gov> Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From:Venigalla B Rao [mailto:, Cb) (6)J Sent: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Suzanne Peskin -------~ (b~)-(= Sent: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Sent: To : Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Sent: Tuesday, February 18, 2020 8:04 AM To : Fauci, Anthony (NIH/NIAID) [E) Subject : (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Sent: To: Subject : Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To : Subject : Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Sent : Tuesday, February 18, 2020 4:40 AM To : Fauci, Anthony (NIH/NIAID) [E) Subject : Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) <@nbcuni.com> Sent: Tuesday, February 18, 2020 12:26 AM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com> ; Varela, Jay (NBCUniversal) <@nbcuni.com>; Mitchell, Alexander (NBCUniversal) <@nbcuni.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com> ; Metsch, Abigail (NBCUniversal) <@nbcuni.com> Subject : RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Sent: Monday, February 17, 2020 8:19 AM To : Sheeley, Colin (NBCUniversal) <@nbcuni.com > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal) <@nbcun i.com>; Mitchell, Alexander (NBCUniversal) <@nbcun i.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcuni.com > Subject : [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) <@nbcuni.com > Sent : Monday, February 17, 2020 3:36 AM To : Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal ) <@nbcu ni .com>; Mitchell , Alexander {NBCUniversal) <@nbcuni.com >; DiCasimir ro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcun i.com > Subjec t : NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) <@turner .com> Sent: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc:Pfeifer, Hazel <@turner .com>; Avramova, Nina (NE) <@turner.com> Subject : CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Sent: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" <@t urn er .co m> Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" <@turne r.com >, Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike <@t urn er .co m> Sent: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 <@t urner .com> Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject : RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike <@tu rn er.co m> Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject : Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike <@tu rn er .com > wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject : Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Se nt: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date : Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From : Angela Moore (b)(6);, Sent : Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject : COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Sent : Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To : bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject : RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty <@manuscriptcentral.com> Sent: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. Additional information about disclosure of financial and other associations appears below this letter. Please bear in mind that your editoria l represents your (and any coautho r's) personal opinion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal po licy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manuscript can be accepted. Therefore, the enclosed form should be signed by all authors and faxed to (781) 207 -6529. Your editorial is due at the Journa l on Monday, February 17, at the very latest if the deadline imposed by our printing schedule is to be met. ff the editorial is to include a figure, please submit the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. Please provide a title not exceeding 45 characters and a word count for the text; the entire manuscript , including references , should be double-spaced. REFERENCES Cite no more than 10 references , including the article you are writing about. The average collection of 10 references requires about a quarter of a printed page. TABLE OR FIGURE A table or a figure in your edito,ial will require a reduction in the number of words ; because figures and tables vary in size, you may be asked to shorten the text of your editorial during the production process. A quarter-page table roughly equals 250 words , and a half-page table roughly equals 500 words. DISCLOSURES When completing your disclosure fonn , please indicate, in the "Comments" field next to the type of relationship being disclosed, the amount (in U.S. dollars) of any support you have received. Please also indicate how much of NIH-001808 this support has been received over the past 2 years. Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject : FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Se nt: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject : Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From : John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To : AFAUCI @N I AI D. NIH . GOV Sub j ect : Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Se nt: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject : Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Sent : To : Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Sent: To: Subject : Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Sent: To: Subject : Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Townsend, Frances <@l\1AFGRP.COM> Sent: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h <@MAFGRP.COM > Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Sent : To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Fitzgerald, Kate <@umassmed.edu> Se nt: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish <@utoronto.ca> Subject : COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Sent: To: Subject : Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com <@happeningsmag.com > Sent: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Sent: To : Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Jodie Dillman --------~ (b ~)~(6) => Sent: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To : Subject : outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedviginc.com> Se nt: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko <@hedvigin c.com> wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedv iginc.com> Se nt: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles <@newshour .org> Se nt : Monday, February 17, 2020 11:51 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven <@....__ 1 Cb _>< ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" <@turner.com > Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From : Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:42 AM To : Figliola, Mike <@turner .com> Subject : RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From : Figliola, Mike <@turne r.com > Se nt : Monday, February 17, 2020 8:40 AM To : Conrad, Patricia (NIH/NIA ID) [E) Subject : RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From : Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:40 AM To : Figliola, Mike <@turne r.com > Subject : Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike <@turner .com > wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike <@tu rner .com> wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Sent: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From:Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike <@turner .com > Sent: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject : RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Thur sday, January 23, 2020 10:00 AM To : Figliola, Mike <@turner .com > Subject : RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike <@turne r.com > Sent: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject : RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Sent: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike <@turne r.com> Subject:RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From : Figliola, Mike <@turne r.com > Sent : Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike <@turner .com> Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" <@tumer.com > Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject : RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To : Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Se nt : Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Sent : Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject : RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From : Sent : Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From : Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Sent: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject : ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---Fr om: Jon LaPook ______ __,(b""' )..,. (= > Sent: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Sent: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B <@providence.org> Sent : Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subj ect : Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Sent : To : Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Sent: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject : one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Sent: To : Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject : NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Sent : Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 <@tovima.gr> Sent: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) <@niaid.nih.gov > Cc: Fauci , Anthony (NTH/NIAID) [E] Subje ct: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From : Fauci, Anthony {NIH/N IAID) [E) Sent : To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject : RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Folkers, Greg (N IH/ NIAID) [E] Sent: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To : Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject : ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Sent: Monday, Apri l 27 , 2020 4:30 PM To : Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject : Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Sent : M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Sent : To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Sent : Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Sent : To: Subject : Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Sent: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Sent : Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Mascola, John (NIH/VRC) [E] CbH > Sent : Tuesday, May 5, 2020 5:0 4 PM To : Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject : FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From : David Montefiori, Ph.D. Sent: Tuesday, May 5, 2020 1:23 PM To : Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Sent : To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Sent: Tuesday, May 5, 2020 3:06 PM To : NIAID OD AM <@niaid.nih.gov> Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com <@leslevcahillroy.com> Sent: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Sent : Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com <@lesleycahillroy.com> Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject : RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com <@lesleycahillroy.com> Sent : Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject : Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From : Les ley Cah ill Roy <@lesle y cah ill roy .com > Subj ect: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com <@lesleycahil lroy .com > wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Konstantin Vulkov <@egoist .bg> Sent: Tuesday, May 5, 2020 3:42 PM To : NIAID NEWS (NIH/NIAID) <@niaid.nih.gov> Cc: NIAID Ocpostoffice (NIH/NIAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Sent: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Sent: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject:AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Sent : (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Sent : (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu <@umbc.edu > Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Sent : Tuesday, May 5, 2020 8:39 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From : Zh uChen Cb)(6)> Subj ect: Re :SARS -CoV-2 Date : May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subj ect: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Sent : To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Sent: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Sen t: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From:Ola Me lhus (b)( Sent: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Sent: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Sent: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject : Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Sent : Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Sent : To : Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Sent: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From : Harris, Kara (NIH/NIAID) [El Sent : Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc:Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Sent : Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Sent : To : Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From:Augustine M. K. Choi Sent: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To : Corey, Larry Subject : FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Dolsten, Mikael (b)(6)> Sent : Monday, May 4, 2020 8:15 AM To : Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis Fro m : Dolsten, Mikael (b)(6)> Sent : Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject : Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Sent: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Sent : Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subje ct : OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From : Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Se nt : Monday, May 4, 2020 6:20 AM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Se nt : Sunday, May 3, 2020 9:54 PM To : OD-OLPA-Leg Contacts <@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From : Yaworske, Jason A. EOP/OMB Sent : Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject : May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Sent : To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Sent: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc:Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Sent: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Sent: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From:Sogaard, Morten Sent: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Sent: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sent: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Sent : To : -----------, (b =~=(6)) ' Cc: Subject : Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Sent: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc:Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date : Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subje ct : FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Sent: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Sent : To : Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Sent : Sunday, May 3, 2020 1:55 PM To : NIAID OD AM <@niaid .nih .gov> Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com <@lesleycahillroy.com> Sent: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com <@lesleycahillroy .com> wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Sent: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject : Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject:2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Sent: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Sent : To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Sent : Thursday, April 30, 2020 6:52 PM To : (b)(6)] (b) (6) Subject : Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From : Sent : To : Subject : Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Sent: Friday, May 1, 20 20 3:09 PM To : Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Sent : Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc:----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject:INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Sent : To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Sent: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Sent: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fro m : Paola Dama (b)(6)> Se nt : Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject : White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From : Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject : Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Sent : Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Sent: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Sent: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Sent : Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To : Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject : RE: From: Sent : Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Sent: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Se nt: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subj ect: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Sent: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Sent : Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject : FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From : Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Sent : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Sent : Monday, April 27, 2020 6:09 PM To : Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subje ct: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject : Please review this draft-----------email to Tony--TX (b)(6) To : (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Sent : To : Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Sent: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To : Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Sent: To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Sent: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject:Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Sent: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To : Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Sent: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El <@niaid .nih .gov>; Harper, Jill (NIH/NIAID) [El (b)( > Cc:Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject : RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From : Johnson, Martin S. (NIH/NIAID) [El Sent : Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc:Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From : Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From : Johnson, Martin S. (NIH/NIAID) [El Se nt : Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From : Johnson, Martin S. (NIH/NIAID) (E] Sent : Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg <@mail.nih.gov >; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Sent : Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg <@mail.nih .gov >; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From:Johnson, Mart in S. (NIH/NIAID) [El Sent: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Sent : Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg <@mail.nih.gov>; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From:Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc:Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From:Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject:FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From : Johnson, Ma rtin S. (NIH/NIAID) [El Sent : Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Sent : To : (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Sent: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Sent: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Sent: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Sent: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To : (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Sent : Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Sent: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From : Sent : To : Subje ct: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Sent: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Sent: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From:Coney, Lillie Sent : Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Sent : To : Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject : FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Sen t: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Sen t : Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Sent : Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject : RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Sent : Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Sent: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Sent : Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From:Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Sent: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc:NIAID OCGR Leg <@mail.nih.gov>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Routh, Jennifer (NIH/ NIAID) [E] (b)( > Se nt : Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Sent: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Sent : To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject : FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Sent : Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject : RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From : Beige!, John (NIH) (E] -------- Sent : Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To : Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subje ct: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date : Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Sent: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date : Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From : Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From : Dani Bolognesi, Ph.D. Se nt : Thursday, April 30, 2020 8:13 PM To : Fauci, Anthony {NIH/NIAID) [E] Subje ct : RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Sent : Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Sent : Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject : FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Sent : Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subjec t : FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From:"Dani Bolognesi, Ph.D." Date : Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject : Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Sent : To: Subject : Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Sent : Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject : FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Sent : Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subje ct: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<@ethnos.gr> Sent: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 Ato: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Sent: Friday, May 1, 2020 4:53 AM To : Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Sent : To : Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject : FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Se nt : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From : Dani Bolognesi, Ph.D.________ Sent : Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From:"Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date : Monday, April 27, 2020 at 2:53 PM To : "Matthias Gromeier, M .D." (bH Subject : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Jere my Farrar _________ Sent: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. <@nas.edu>; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma <@nas .edu>; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny <@nas .edu> (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau <@nas.edu> , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " <@nas.edu> , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " <@cnn.com>, "Amanda.Se aly@c nn.com " <@cnn.com >, "Neel.Kbairzada(a),turner.com " <@turner.com> , Cb)(6) "McGinnis, J.Mic hael" <@nas.edu> , CbH6) >, ''Mun , Jenny" <@nas.edu >, CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Sent : Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. <@nas.edu>; George (b)(6) ____ ; Hannon, Emma <@nas.edu>; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael<@nas.edu>; (b)(6)>; Mun, Jenny <@nas.edu > (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date : Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau <@nas.edu >, George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " <@cnn .com> , "Amanda.Sealy@cnn .com " <@turner.com " <@tumer.com> , (b)(6)"McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenny" <@nas.edu >, (b)(6) Emma" <@nas.edu >, "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. <@nas.edu> Sent: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma <@nas.edu>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. <@nas.edu> '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From : Dzau, Victor J. <@nas.edu> Se nt : Thursday, Apr il 9, 2020 11:01 AM To : Mun, Jenny <@nas.edu >, ------~~ (b)(6) ; 'ben.tinker@cnn .com ' <@cnn.com >; 'Amanda.Sealy@cnn .com' <@cnn.com >; 'Neel . Khairzada@turner.com' <@tumer.com >; (b)(6) 'Tia.Mi ller@turner.com' <@turner.com >; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Sent: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson <@beatthebomb Se nt : Thursday, April 30, 2020 11:26 AM To : Fauci, Anthony (NIH/NIAID) [E) .com> (b)(6)> Cc: Daniel Lahart <@r egis.org> Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson <@beatthebomb .com> Sent : Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] <@niaid .nih.gov > Cc: Daniel Lahart <@regis.org> Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To : (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Sent: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Sent: Tuesday, April 28, 2020 11:19 Atvl To : Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Sent : To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Sent : Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subj ect: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From : Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject : (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Se nt : Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Sent: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff <@svt.se> Sent: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc:NIAID NEWS (NIH/NIAID) <@niaid.nih.gov>; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Sent : To: Cc: Subjec t : result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIAID) [E] (b)(6J> Se nt : Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject : Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From : Sent : To: Cc: Subject : Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Sent : Thursday, April 30, 2020 5:44 AM To : (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject : COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From : Sent : To : Subject : Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Se nt : Wednesday, April 29, 2020 10:21 AM To : Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Se nt: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Sent: To : Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Wednesday, April 29, 2020 5:03 PM To : NIAID OD AM <@niaid .nih.gov> Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen <@brt .org > Sent: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Sent : Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Sent: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Sent: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] <@niaid.nih.gov> Sent: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] <@niaid.nih.gov> Cc: Folkers, Greg (NIH/NIAID) [El <@niaid.nih .gov>; Conrad, Patricia (NIH/NIAID) [El <@nih.gov>; Routh, Jennifer (NIH/NIAID) [El <@nih .gov>; Lane, Cliff (NIH/NIAID) [El <@nih.gov> Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject : RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To : Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Sent: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sent: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc:Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Sent: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Sent: Tuesday, April 28, 2020 9:57 PM To : Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Sent:Tuesday, April 28, 2020 9:21 PM To : Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject:ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From:Lane, Cliff (NIH/NIAID) [El _______ Sent: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From:Lane, Cliff (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Sent : To : Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Sent: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Sent: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To : Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Sent: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To : Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Sent : To: Subject : Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subj ec t: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject : Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From : Sent : Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Sent : To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedi a.co m> Sent: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From:"Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias <@ikanamedia.com > Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Sent : To: Subject : Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Sent : Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Sent : To : Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Sent : Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Sent: Tuesday, April 28, 2020 7:08 AM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Sent : Tuesday, April 28, 2020 7:04 AM To : Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Monday, April 27, 2020 8:20 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Dat e: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg <@mail.nih.gov>, " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Dat e: April 27, 2020 at 7:57:36 PM EDT To : "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject : Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To : "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject : LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Sent : Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To : Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Sent: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From : Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Sent : Monday, April 27, 2020 6:09 PM To : Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To : "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subje ct : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Sent: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM <@niaid.nih.gov > this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Sent: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM <@niaid.nih.gov > Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Sent: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From : Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Sent : To : Subject : Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Sent: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subje ct: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Sent: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subje ct : Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Sent: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From:"Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date : Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Sent : Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc:Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From : Sent : To : Cc: Subject : Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Sent: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From : Sent : To : Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject : Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From : Sent: Monday , April 27, 2020 3:0 1 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sent: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From:Taylor Taglianetti <@noiaft.org> Sent: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG <@niaid .nih.gov> Cc:NIAID COGCORE<@mail.nih.gov>, NIAID Media Inquir ies <@niaid.nih.gov> Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Sent: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang <@sinobio logical.info> Sent : Monday, April 27, 2020 8:04 AM To : Anderson, Cassandra (NIH/NIDDK) [E) Subjec t : Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia <@la7.it> Sent: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Sent : To : Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Sent: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM <@niaid .ni h.gov> (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Sent : Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From : Miller , Amanda <@paypal.com > Sent : Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay <@edelman.com > Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Sent : To : Subjec t : (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Sent: Monday, April 27, 2020 10:05 AM To : Fauci, Anthony {NIH/NIAID) [E) -----Subjec t: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! Fr om : "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: Upd ate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de > Se nt: Wednesday, Apr il 22, 2020 9:41 AM To : Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc:'-:-""'."""".~-:----::== Subje ct: Update: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf <@syntacoll.de> Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Sent : Wednesday, Apr il 8, 2020 2:49 AM To : Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf <@syntacoll.de> -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Sent : Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Sent : Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.<@nas.edu>; George (b)(6) ; Hannon, Emma <@nas.edu>; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael <@nas.edu>; (b)(6) Mun, Jenny <@nas.edu>; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau <@nas.edu >, Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" <@nas.edu> , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" <@cnn.com>, ------------- (b) (6) "Amanda. Sealy@cnn .com " <@turne r.com " <@turner.com >, (b)(6) "McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenn y" <@nas.edu>, CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Sent: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.<@nas.edu>; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma <@nas.edu>; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael<@nas.edu>; (b)(6)> ; Mun, Jenny <@nas.edu>; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau <@nas.edu >, George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" <@nas.edu >, "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " <@cnn.com >, "Amanda.Sealy@cnn.com " <@turner.com " <@turner.com > , (b)( 6) "McGinni s, J.Mi chael" <@nas.edu >, ---------------- CbH6) >, "Mun, Jenny" <@nas.edu>, (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.<@nas.edu> Sent: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc:Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a <@nas.edu >; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. <@nas.edu> Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.<@nas.edu> Sent: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' <@cnn.com >; ---------'Amanda.Sealy@cnn.com ' <@cnn.com >; 'Neel. Khairzada@turner .com' <@turner.com >; 'Tia.Miller@turner .com' <@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny sent: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie <@ncdps.gov> Sent: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Sent : To : (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject : RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Sent : Sunday, May 3, 2020 7:37 AM To : Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To : "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subj ect : Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Sent : Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From : Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To : Subject : Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Sent: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date : Apr il 30, 2020 at 5:46 :27 PM EDT To : Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Sent: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Sent : Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject : RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Sent : Monday , April 27, 2020 9:04 AM To : Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Se nt : Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie <@fda.hhs.gov> Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards from: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From : Fauci, Anthony {NIH/N IAID) [E) Sent : To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject : RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Folkers, Greg (N IH/ NIAID) [E] Sent: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To : Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject : ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Sent: Monday, Apri l 27 , 2020 4:30 PM To : Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject : Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Sent : M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Sent : Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Sent: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From : Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From : Lane, Cliff (NIH/NIAID) [El Se nt : Sunday, May 3, 2020 1:22 PM To : Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Sent: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Sent: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Sent : Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Sent : To : Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subje ct: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Sent : Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subje ct: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Sent : Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subje ct: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From : Kadlec, Robert (OS/ASPR/10) (b)(6) Sent : Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subje ct: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Sent : To : Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Sent : Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) <@mail.nih.gov> Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig Fro m : Brennan, Patrick (OS/ASPA) (b)(6)> Sent : Wednesday, April 29, 2020 10:33 AM To : Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject : For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Sent: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Sent: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Sent: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Sent: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To : Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From:Secretary ARP (b)(6)> Sent : Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Sent : To : (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Sent: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Sent : Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From : Sent : To: Cc: Bee: Subject : Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From : Collins, Francis (NIH/OD) [El Se nt : Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Sent : Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Sent: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Sent: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Sent : To: Cc: Subjec t : Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Se nt : Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject : FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From : Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo <@lastampa.it> Sent: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subjec t : Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat <@hivr4p.org> Se nt : Thursday, April 23, 2020 11:23 AM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From : HIVR4P- Secretariat Sen t : 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject : HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From : Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Se nt : Thursd ay, Apr il 23, 2020 5:02 PM To : Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Sent: Tuesday , April 21, 2020 11:18_ A _M ____ To : Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Sent: Sunday . April 19, 2020 5:04 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Sent: Sunday , April 5, 2020 9:23 PM To : Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Sent: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Sent: Thursday, April 23, 2020 8:31 PM To : Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Sent: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier <@ourpubl icservice.org> Sent: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc:Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies <@ourpublicserv ice.org> Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To : Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject : FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Sent : FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. <@nas.edu> Se nt : Thursday, Apr il 23, 2020 1:49 PM To : Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma <@nas .edu>; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' <@cnn .com>; 'Amanda.Sealy@cnn.com' <@t urner .com' <@turner .com> ; (b) ( >; McGinni s, J. Mic hael <@nas.edu>; (b)( (b)(6) ; Mu n, Jenny <@nas .edu>; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Sent: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma <@nas.edu>; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' <@cnn.com' <@t urne r.com>; 'Tia.M iller@turner .com' <@turner.com >; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Sent : Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Sent : To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Sent : Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc:Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Sent: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Sent: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Sent: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From : David Liu (b)( Se nt: Thursday, April 23, 2020 6:01 PM To : Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Sent : Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc:Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From : Sent : To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Sent: To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Updat e: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To : Fauci, Anthony (NIH/N IAID) [El Subject : FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From : Sent : https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Se nt : Thursday, Apr il 23, 2020 9:04 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Sent : Tuesday, April 21, 2020 11:06 PM Subje ct: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Sent : (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith <@one .org> Date : April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart <@one.org> Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Sent: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Sent: Friday, March 27, 2020 11:55 AM To: NIAID Announcements <@niaid .nih.gov> Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Sent : Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To : Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject : FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Sent : Thursday, April 23, 2020 1:05 PM To : Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman<@sanaria.com> Sent : Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Sent: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Sent: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Sent : Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Sent: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject : Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Sent : To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Sent: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc:Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Se nt: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject : Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Sent : Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject : RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From : Pardis Sabeti (b)(6 )> Sent : Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject : Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Sent: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden <@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Sent : (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject : Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C <@who .int> , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC <@who.int> , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Sent : Thursday, April 23, 2020 10:51 AM To: SHOC <@who.int>; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC<@who .int>; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From : Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( sent: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Sent : To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i <@fortaleza.pr.gov> Sent: Wednesday, April 22, 2020 5:24 PM To : Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan <@prfaa.pr .gov>; Juan L. Negron <@fortaleza.pr.gov>; Antonio L. Pabon Batlle <@forta leza.pr.gov> Subject : letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Sent : To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From:Alice Park <@time.com> Sent: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov>;Conrad, Patricia {NIH/NIAID) [El <@niaid.nih.gov> Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Sent : To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Sent: To: Cc: Subject : Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From : Billet, Courtn ey (NIH/NIAID) [E) Sent : Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams <@caa.com> Se nt: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman <@caa.com> ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date : Tuesday, Apr il 21, 2020 at 4:41 PM --------- To : Judee Williams <@caa.com> Cc: Christine Lancman <@caa.com>, (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject : RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams <@caa.com> Sent : Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc:Christine Lancman <@caa.com > Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recip ient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexual harassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Sent : Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject : FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Sen t: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg {NIH/NIAID) [E] (b)( > Sent : Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Sent : Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject : FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Sent : Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: For your attent ion (b)(6) (b) (5) From:Anthony Fauc i Cb)<> Date : Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Sent : Tuesday, April 21, 2020 7:28 PM To : Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl <@fnih.org> Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From:Dzau, Victor J. <@nas.edu> Sent : Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan <@nas.edu> Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Sent : To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From : Gary Noble (b)(6) Sent : Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject : Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Sent : To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha <@calhacks.io> Sent: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Sent: Tuesday, April 21, 2020 11:31 AM To : Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Sent: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc:Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Sent : Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Sent: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject : FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Sent : Tuesday, April 21, 2020 3:01 PM Subject : STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Sent: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Sent: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent: Tuesday, April 21, 2020 4:43 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams <@caa.com> Cc: Christine Lancman <@caa.com >; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams <@caa.com> Sent: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman <@caa .com> Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From : Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Conrad , Patricia (NIH/NIAID) [E) Se nt : Tuesday, April 21, 2020 4:41 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Dat e: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subje ct : Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date : April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject : Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date : T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From : COVID19 Treatment Guidelines <@nih.gov > Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali <@turner.com > Sent : Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines <@nih.gov > Cc: Cohen, Elizabeth <@turner.com >; Fine, Amanda (NIH/OD) [E] (b)( > Subjec t : urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject : FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Sent : Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From : Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim <@global -infra.com> Sen t: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Sent: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject : Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Sent: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Sent: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Sent: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Sent: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen <@rockfound .org> Sent: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] <@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From : Sent: To : Subject : Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) Sent: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Se nt : Monday, April 20, 2020 7:55 AM To : Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject : Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Sent : Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From : Sent : To : Subject : Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Sent : Sunday, April 19, 2020 6:28 PM To : Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield <@uw.edu > Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld <@uw.edu > Date : Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Sent : Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield <@uw.edu> Subject : FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From : Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Sent : To: Subject : Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Se nt : Sunday, April 19, 2020 9:08 PM To : Collins, Francis {NIH/OD) [E] Cc : M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Sent: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc:Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subjec t: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Sent : To: Cc: Subjec t : Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz <@w ashingtontimes.com > wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Sent : Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To : Cc: Subjec t : Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Sent : Sunday, April 19, 2020 7:06 PM To : Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Sent : Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.<@nas.edu> Sent : Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny <@nas.edu > Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Sent : To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Sent : Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject : Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Sent: To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From : Jake Tapper (b)(6) Sent: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subje ct: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) Update: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Sent: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Sent: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Sent: To: Cc: Subjec t : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Sent: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject : You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. <@duke.edu> Sent : Thursday, Apr il 16, 2020 12:39 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Billet, Courtney (NIH/NIAID) [E) (b)(6) Se nt : Thursday, Apr il 16, 2020 1:45 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Sent : To: Subject : Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: Fr om : "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To : SHOC (b)(6) , Office of the Director-General <@who.int> , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s <@resolvetosave lives.org>, "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC <@who.int>, "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Sent: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Sen t : Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject : High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To : Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subje ct: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From:Shapiro, Neil (NIH/OD) (El (b)(6)> Sent: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Sent : To : Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Sent: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Sent : Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Sent : Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Sent: Sunday, April 26, 2020 8 :37 AM To : Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Sent : Saturday, Apr il 25, 2020 5:59 PM To : Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Sent : Saturday, Apr il 25, 2020 5:50 PM To : Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Sent : Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subje ct: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Sent: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc:Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine <@manuscriptcentral.com > Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" <@niaid.nih.gov > Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " <@nejm.org > Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From:Adrian Hill Sent: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To : Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Sent : To : Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Sent: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc:Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Sent: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To : Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From:Yewdell, Jon (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Sent: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Sent: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Se nt: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date : Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subj e ct : Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Sent: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: Update: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de> Sent: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf <@syntacoll.de> Subject: Update : Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf <@syntacoll.de> Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf <@syntacoll.de > Sent: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf <@syntacoll.de> Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From:Xizhong, Cui (NIH/CC/CCM D) [E] Sent: Sunday, April 26, 2020 8:36 PM To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Sent : Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM <@n iaid.nih .gov> Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. Fro m : Kristina Horton <@keystonesymposia.org> Sent : Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subjec t: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Sent : To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Sent: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc:Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject : FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith <@one.org> Sent: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart <@one.o rg> Subje ct : Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy <@bclplaw .com> Sent: Thursday, April 23, 2020 10 :26 AM To : Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Sent : To : Cc: Subjec t : Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Gayle Smith <@one.org> Sent : Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart <@one .org> Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Se nt: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc:"Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Sent: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe <@washpost.com> Sent : Friday, April 24, 2020 12:58 PM To : Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent : Friday, April 24, 2020 3:04 PM To : NIAID COGCORE<@mail.nih.gov> Cc: NIAID OD AM <@niaid.nih.gov> Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Sent : To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton <@keyston esymposia .org> Sent: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Sent: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Sent: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Sent: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Sent : To: Subject : Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Sent: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Sent: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Sent : To : Subject : Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From : Joh n Lauerman 1 8 : 46: 1 6 To : Cc : (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To : John Cc : (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Dat e: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Sent : Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subje ct : spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To : Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Sent: Friday, April 17, 2020 7:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From : Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject : RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Sent : Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Se nt : Friday, Apri l 17, 2020 8:03 AM To : Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subj ect : impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviato: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) Oggetto : RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Sent: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviato: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] Oggetto: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviato: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) Oggetto: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Sent:Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject:all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Sent: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Sent: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Sent: Tuesday, April 21, 2020 3:46 PM To : Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Sent : Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) <@service.gov deli very.com > Sent : Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Sent: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Sent: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc:Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Sent: To: Subject : Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From : Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject : FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Sent : Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject : Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Sent : To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Sent: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subje ct : Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From : Sent: To : Subject : Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Hahn, Stephen (b)(6):> Se nt : Tuesday, April 21, 2020 3:23 PM To : Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subj ect: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date : Apr il 20, 2020 at 6:26 :14 PM EDT To : Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To : Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subje ct: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Sent: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc:Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To : Hahn, Stephen (b)(6) (b)(6) Cc : Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Sent : Saturd ay, Apr il 18, 2020 3:25 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To : Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject : RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Hahn, Stephen (b)( > Sent : Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject : Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc:Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Sent: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To : Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Sent : Monday, April 20, 2020 10:07 PM To : Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From:Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Sent: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Sent : To : Subject : Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg (NIH/NIAID) [El (b)(6)> Sent : Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM <@ni aid .nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Sent : Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM <@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] <@niaid.nih.gov> Sent : Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]<@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [E] <@nih .gov>; Routh, Jennifer (NIH/NIAID) [E] <@nih.gov > Subject : RE:ask to highlight the incredible work of key federal worke rs (b)(5) From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Monday, April 20, 2020 4:40 PM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject : FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From : Boyse, Natalie (OS/ASPA) (b)(6)> Sent: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject : FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Sent: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Sent: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Sent: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc:Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Sent: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Sent: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc:Conrad, Patric ia {NIH/NIAID) [E] ---------Subject : RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Sent : Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject : FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subje ct: RE: Pursuant to My Email on Friday Sent: To: OK. Let us discuss tomorrow. (b)( > From : Mascola, John (NIH/VRC) [E] Sent: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc:Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Sent: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc:Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Sent : Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc:Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Sent: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc:Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To : Cc: Subjec t : Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) MEDCOM (USA) Se nt : Tu esday, April 21, 2020 9:58 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Sent : Tuesday, April 21, 2020 12:49 PM Cb_H_6) To : (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subjec t: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Se nt : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Se nt: Tuesday, April 14, 2020 9:13 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From : (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From : Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From : (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Sent : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Sent: To: Subje ct: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Benoit Ponton <@cpa -qc.ca> Sent: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp CC: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Sent: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Se nt : Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Sent : Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc:Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Sent: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Sent : Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Sent: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Sent: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Sent : To : Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject : RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Sent : Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From : Sent : To: ------- Robert (OS/ASPR/10) Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/N IAID) [E] (b)(6) Sent : Saturday, Apr il 18, 2020 1:54 PM Subject : Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Sent : (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Sent : (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner <@jamanetwork.org > Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa <@jamanetwork.org > Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner <@jamanetwork.org> Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To : Howard Bauchn e r <@jaman etwork.org> Subject : Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Sent : Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To : CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Sent : Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM <@niaid.nih.gov> Subject : Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Sent : (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject : Let us make sure that we discuss this. Begin forwarded message: Fr om : Alice Park <@ti me .com > Date: April 17, 2020 at 2:07 : 17 PM EDT To : "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews <@time.com > Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park <@time.com>w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Sent: To: Subject : Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Sent : To : Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana <@bizsecure .us> Sent: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Sent: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Sent : Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To : Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Sent: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Sent: Thursday, April 16, 2020 6:53 PM To : Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff <@whmo.mil> Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Sent: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject : [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To : Subject : You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon <@mail.huji.ac.il> Sent : Thursday, April 16, 2020 8:09 AM To : Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject : Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon <@mail.huji .ac.il> Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon <@mail.huji.ac.il> Sent: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Sent : To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Sent: Monday , Ap ril 13, 2020 2:49 AM To : Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject : Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To : Cc: Subjec t : Thanks, Dan. Best, Tony From: Daniel Bednarik <@neximmune .com> Se nt : Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Sent: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To : Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject : RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From:Schwetz, Tara (NIH/OD) [E) (b)(6)/> Sent: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date : Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date : TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From : Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Sent: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Sent: To : Cc: Subject : Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Sent: Tuesday, April 14, 2020 8:52 PM To : ICDDIR-L@list. nih.gov Cc: List DEPDIR-L <@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To : Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Sent: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Sent: Wednesday, April 15, 2020 7:18 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Sent : To : Subject : Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano <@asmusa.org> Sent : Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To : Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Sent: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc:List DEPDIR-L<@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From:Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " <@list.nih.gov > Cc: List DEPDIR-L <@list.nih.gov >, NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To : My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Sent: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Sent : Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Sent : Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole <@lewis -burke .com> Sent: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby <@lewis-burke.com > Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From : Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Sent: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Sent: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Sent : To : Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Sent: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Sent : Sunday, April 12, 2020 7:20 PM To : Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Sent : Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From:Miller , Darin B. EOP/OVP Sent : Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Sent: Tuesday, Apr il 14, 2020 6:13 PM To : Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subje ct: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Sent: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc:Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Sent : (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" <@nbcuni.com> , Jeremy Schu lman <@schulmanbh.com > Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller <@schulmanbh.com> Sent: Monday, April13, 2020 5:36 PM To : Mollet, Me lissa {NBCUniversal, WRC) Subject : [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Sent : To : Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) <@knowledgeu.com> Sent: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc:Billie Griffin (bgriffin@knowledgeu.com) <@knowledgeu.com>; Katie Dinsmore (kdinsmore@knowledgeu.com) <@knowledgeu.com> Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Sent: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Sent : To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From:Julio Gali (b)(6) Sent: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred <@washpost .com> Sent : Monday, April 13, 2020 2:30 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Sent: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject : RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Sent : Monday, April 13, 2020 12:50 PM ------ --~ To : Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Sent: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subje ct: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To : 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Sent: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From : Conover, Craig_________ Cb _H_6) Se nt : Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached Fro m: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Sent : Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject : [Extern al] RE: UPDATE:COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDATE: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Se nt : Monday, April 6, 2020 5:22 PM To : Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Sent: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From : Kilmarx, Peter (NIH/FIC) [E] Sent : Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject:* ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Sent: Thursday, April 2, 2020 1:29 PM To : 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Sent: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subje ct: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Sent: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subje ct: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subje ct: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Sent: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Sent: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc:A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From : Conover, Craig_________ Cb _> _<_ > sent: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject : Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From : Kilmarx, Peter (NIH/FIC) [E] Sent : Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject : [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to CC: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From : Kilmarx, Peter (NIH/FIC) [E] Sent : Sunday, March 22, 2020 12:35 PM To : Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From : Kilmarx, Peter (NIH/F ie) [El Sent: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Sent: To: Subject : Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Sent: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Sent : Sunday, April 12, 2020 11:31 PM -------, To : Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc:Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Sent: Monday, Apri l 13, 2020 8:12 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Sent: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject:FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From:WAYNE REYNOLDS Sent: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Sent: To : Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:t Sent: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@goog le.com > Sent: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Se nt : Monday, April 13, 2020 6:07 AM ------~~ -------- To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Sent: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Sent : Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Sent : To : Subject : Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park <@immunemed .co.kr> Sen t: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subject : FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. <@nas.edu> Sent: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny <@nas .edu>; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma <@nas .edu>; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' <@cnn.com' <@t urner.com>; 'Tia.M iller@turner.com' <@turner.com>; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny <@nas.edu> Sent: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' <@cnn.com>; 'Nee l.Khairzada@turner.com' <@turner.com' <@turner.com> Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From : Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Sent: Saturday, March 28, 2020 3:48 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Sent : Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From : Sent : To : Subject: Thanks,John. ------------ From: Holdren, John P. Sent: Wednesday, March 25, 2020 4:27 PM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Sent : Wednesday, March 25, 2020 3:57 PM To : Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Sent : Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Sent : Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To : (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Sent: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To : Cc: Subjec t : REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Sent : Monday, March 30, 2020 9:38 PM To : Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Se nt: Monday, March 30, 2020 10:17 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date : March 30, 2020 at 1:15:06 PM EDT To : Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Sent : To : Cc: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Sent : Thursday, April 2, 2020 4:04 PM To : Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) F rom : "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From:Susan Corrigan (b)(6);,, sent: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Sent : Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Sent : To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Sent: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Sent: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Sent : Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject:ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney <@topspinconten t.com> wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Sent: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Sent: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From:Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From:Viswanathan Neelakantan Sent: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Sent : To: Subject : ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To : Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Se nt : Sunday, April 12, 2020 8:47 AM To : Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Sent: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Se nt : Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Sent : Thursday, March 26, 2020 12:59 PM To : Barton Haynes, M.D. _________ Subje ct: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Sent: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Sent: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM <@niaid.nih.gov> Cc:Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn <@ap.org Sent: Sunday, April 12, 2020 10 :56 AM To : Fauci, Anthony (NIH/NIAID) [E] ------~= > CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Sent: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Sent: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Sent : Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent: Sunday, April 12, 2020 10:31 AM To : Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Se nt : Sunday, April 12 , 2020 1 :10 PM To : Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Se nt : Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Sent: Sunday, April 12, 2020 1 :06 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From : Fauci, Anthony (NIH/NIAID) [E] -------Sent : Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subjec t : RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent: Sunday, April 12, 2020 10:31 AM -------~~- To : Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT<@state .co.us> Se nt : Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Sent: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent : Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc:Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Sent : Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Sent: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Sent : Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Sent : ----------------From : Sunday, April 12, 2020 5 :54 AM [E] To : Fauci, Anthony (NIH/NIAID) Subject : ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Sent : To: Cc: Subjec t : (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Sent : To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From:Gold, Jeffrey P (b)( > Sent : Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subje ct: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date : Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Sent: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject : Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Sent: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Sent : (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Sent : (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias <@ikan amed ia.com>wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Sent: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM <@niaid.nih.gov> Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon <@jsg.utex as.edu> Sent: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Sent : To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall <@editoria lmanag er.com> Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Sent : To: Cc: Subjec t : Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Jack Killen (b)(6) Sent: Tuesday, April 7, 20201 :31 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subje ct : From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : George GAO (b)(6) Sent: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Sent: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject : Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Sent: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From : Maryja ne Walker Subject: Catching up Date : Apri l 6, 2020 at 9:23:13 PM EDT To : CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Sent: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Sent: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From:Crawford, Chase (NIH/NIAID) [El Sent: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From : Fauci, Anthony (NIH/N IAID) [E) Sent: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To : Subject : FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From : Folkers, Greg (NIH/NIAID) [E] Sent : Friday, April 10, 2020 5:30 PM Subject : Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Sent : (b)(6) Subje ct: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent : Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Sent : To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subjec t : RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Del Rio, Ca rlos ______ (b ""')'""" (= Sent: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject : FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Sent: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Sent : (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From:David Bradley <@theatlantic.com> Sent : Friday, April 10, 2020 10:20 AM ------ To : Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Sent : To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From:David Bradley <@theatlantic.com> Sent: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Sent : Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Sent: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Sent : Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject : FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From : Corey MD, Larry (b)(6)> Sent : Thursday, April 9, 2020 3:50 PM ------ ~= To : Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject : COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Sent : (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX <@radio-canada.ca> Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" <@niaid .nih.gov>, "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Sent: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From : Sent : To : Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIAID) [E] (b)(6) Sent : Thursday, Apr il 9, 2020 12:33 PM To : NIAID COGCORE<@ma il.nih .gov>; NIAID OD AM <@niaid.nih.gov> Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante <@outlook.it> Sent: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih.gov> Cc:Barasch,Kimberly (NIH/NIAID) [C) <@nih.gov>;Conrad, Patricia {NIH/NIAID) [E) <@niaid.nih.gov> Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Sent : (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Sent: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC <@who.int> , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) <@resolvetosavelives.org > , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC <@w ho.int> , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) <@nia id .nih .gov> Sent : Wed nesday, Apr il 8, 2020 10:18 AM To : NIAID Announcements <@niaid.nih.gov> Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line <@ors.od.nih.gov > Sent : Tuesday, Apr il 7, 2020 6:23 PM To : NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Sent: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Sent: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Bari llas, Carolina (NIH/NIAID) [El Sent : Wednesday, April 8, 2020 12:39 PM To : Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Sent : To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@google.com> Sent: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Conrad, Patricia (NIH/N IAID ) (E] Sent: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From : Billet , Courtney (NJH/NTATD) [E] ______ Sent: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Sent: Wednesday, April 8, 2020 8:56 AM To : Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc : NlAlD OCGR NSWB <@mail.nih .gov> Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Sent: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Sent : Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Sent: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To : Subject : Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Se nt: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To : Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Su bje ct : WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Sent: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Sent: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc:Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From:Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject:[EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject : [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Sent: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject : FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From : Shawn O'Nea il Dat e: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subj ect: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 9:31 AM To : Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subje ct: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Sent : Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subje ct: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Sent: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From:Chris Joffe <@joffeemergencyservices.com> Sent: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Sent: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Sent: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Sent : Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From : Sent : Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From : Sent: To : Cc : [E] ----~ Subject : Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Bari llas, Carolina (NIH/NIAID) [E] Sent : Tuesday, April 7, 202011 :04 AM To : Fauci, Anthony (NIH/ NIAID) [E] Cc : Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Sent : Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Sent: Friday, April 3, 2020 3 :34 PM To : Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc:Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: <@pnascentral.org> Date : Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To : ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Se nt: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date : April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subj ect: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Sent: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To : (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Se nt: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Se nt : Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Sent : Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subjec t : Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Se nt : Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject : Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Sent : Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From:Chen, Huabiao, M.D. Sent: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject : I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Sent: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Sent : Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject : Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Sent: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Sent: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Sent: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To : Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Sent : Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Sent: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Sent: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Sent : Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Se nt : Thursday, March 26, 2020 5:40 PM To : Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Sent : Saturday, Apr il 18, 2020 12:33 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To : Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Sent: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Sent : Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, April 15, 2020 10:20 PM To : Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Sent: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Sent: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subje ct : RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Sent: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Sent : Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Sent: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Sent: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Sent: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Sent: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc:Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Sent: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Sent: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Sent: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Sent : (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Sent : To: Subject : Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Sent : To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Sent: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From : Sent : To : Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Sent : Wednesday, April 8, 2020 9:49 AM To : (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Sent: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Sent : To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Sent: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From : Freire, Maria (FNIH) [T] Se nt : Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From : "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To : "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Se nt : Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Sent: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Sent: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Sent : Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject : Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Sent : To : Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Sent : Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc:Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subje ct: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From : Sent: To : Subject : alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From : Kavesh, William (b)( > Sent: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Sent : To : Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Sent: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Se nt : Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subjec t: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert <@pennme d icine.upenn.edu > Sent : Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an Update : VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Mark Feinberg Sent : Saturday, Apr il 4, 2020 4:10 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subje ct: Gr eetings and an Update : VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Sent : To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Sent: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Sent : Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Sent: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Sent : To : Cc: Subjec t : M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando <@ma rianneorlando .com> Se nt : Friday, April 3, 2020 6:55 PM -----~= To : Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject : FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Sent: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Sent: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From : Sent : To : Subject : Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From : Jameson, James L Sent : Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subjec t: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subje ct : Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Sent: To: Cc: Subje ct : FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs <@usc.edu> Sent: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Sent: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To : Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Sent: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Sent: Sunday, April 5, 2020 11:37 AM To : Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc:Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From : RIOUX,Amelie Sent: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Sent: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From : RIOUX, Amelie Sent: Tuesday, 31 March 202009:17 To : 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' <@nic.in >; Toomas (b)(6)>; GPMB Secretariat <@who.int >; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subjec t: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Sent : Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' <@nic.in >; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From : SMITH, Ian Michael Sent: Friday, 27 March 2020 19:19 To : (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' <@nic.in >; Toomas Palu GPMB Secretariat <@who.int >; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Sent: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Sent : To: Subject: death Thanks, Teresa. From: Teri M cPeak <@live.ca> Sent: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From:Silver, David (NIH/NCI) [C) Sent: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Sent : To: Subjec t : (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Sent : To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Sent: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: Fro m : Zach Davi s <@thetrek.co > Date : Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From : Fauci,Anthony (NIH/NIAID) [E) Sent : Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subjec t : RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Sen t: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Sent : To : Subjec t : Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Sent : Saturday, Apr il 4, 2020 10:26 AM To : (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject : Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Sent : To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Sent : To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Sent : To : Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Sent: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Sent: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Sent: Thursday, April 2, 2020 9:58 AM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Sent : To : Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Se nt : Thursday, April 2, 2020 6:05 PM To : Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From : Julie Makani <@blood.ac. tz> Sent : Wednesday, April 1, 2020 5:46 PM ------~= To : Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From : Lerner, Andrea (NIH/NIAID) [El Se nt: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject : My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Sent: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From:Balasundaram, David (NIH/CSR) (E] Sent: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc:Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Sent : To: Subjec t : (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Sent: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Sent: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" <@w ashpost.co m> Date : Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar <@bobbleheadhall.com> Sent : Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary <@washpost.com> Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Sent: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Sent: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L <@list. nih.gov> Cc:NIH Director's Executive Committee <@mail.n ih.gov> Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " <@list.nih.gov > Cc: NIH Directo r's Executive Committee <@mail.nih .gov > Subje ct : COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Sent: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 <@globalreporter.it > Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To : Subjec t : fyi From: Brendan Taglianetti <@milfo rd.nh.gov> Se nt : Thursday, April 2, 2020 6:34 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Sent : To: Subjec t : (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G <@nytimes.com>wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar <@bobbleheadhall.com> Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To : <@ny times.com> Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From : Sent: To : Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Sent: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To : Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Sent : Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From : Sent : To : (b)(5)- PC Subject : Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Sent: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To : Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Sent: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Sent: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Sent : To : RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subjec t : It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) Sent : Wednesday, April 1, 2020 9:14 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Sent : Tuesday, March 31, 2020 10:43 AM Subje ct: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Sent : Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subjec t : Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: F rom: Karl Simpson Dat e: Apri l 1, 2020 at 5 :46: 14 AM EDT To : "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Sent : To: Subjec t : Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Se nt : Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Sent : To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin <@arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Sent : To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." <@abgenics.in> Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Sent : To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich <@biosan itize.us> Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor <@b iosan itize.us" <@biosani tize.us> Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From:Moshe Levi Sent: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Sent: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subjec t : FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From : Sent : RSVPso rry no. From: Pinho, Paulo <@optimumre .com> Sen t: Monday, March 30, 2020 8:18 AM To : Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" <@the-times.co.uk > Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" <@mail.huji. ac.il> Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Sent : To: Subjec t : Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From : T im Boyd (b) (6) ---------=.,...,-= Sent: Sunday. March 29. 2020 8:53 PM To : Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Sent: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona <@canyonranch.com> Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From:James Thacker <@therimunex.com> Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona <@canyonranch.com > Cc: Patricia Maxwell <@canyonranc h.com >, "dgrange @osp reyg lobalsol utions.com" <@ospreyg lobalso luti ons .com > Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Sent : To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: F rom: "mton-es8@ myse neca.ca " <@myseneca .ca> Dat e: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Sent: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie <@empowerme.e nterprises> Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To : Subjec t : fyi From: Pat Brittenden <@blindfish .media> Sent : Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Sent : To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue <@demiurge. technology >wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue <@demiurge.technology > Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject : COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Sent : To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject : Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Sent : To: Subjec t : (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From : Sent : ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To : Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Sent : ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subje ct: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Sent: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From : Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco <@cn io.es> Sen t: Saturday, March 28, 2020 3:20 PM To : Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. De conformidad con lo dispuesto en el Reglamento (UE) 2016/679 relativo a la protecci6n de los datos personales de las personas ffsicas, la informaci6n personal que nos pueda facilitar a traves de este correo electr6nico quedara registrada por la Fundaci6n CNIO con la finalidad de tramitar el objeto del presente correo electr6nico . El tratamiento de sus datos personales se encuentra legitimado por ser necesario para gestionar el objeto del presente mensaje. Estos datos personales no seran comunicados a ningun destinatario salvo a aquellos que usted nos auto rice o asf venga exigido por una ley. Ud. podra NIH-000151 ejercer los derechos de acceso, rectificac i6n , supresi6n, limitaci6n de tratamiento , portabil idad y oposici6n en la siguiente direcci6n : c/Melchor Fernandez Almagro 3, 28029 (Madrid). Podra ponerse en contacto con el Delegado de Protecci6n de Datos en: delegado lopd@cnio.es. Para el caso de que Ud. precise conocer informaci6n adicional sobre el tratamiento de sus datos personales, puede consultar dicha informaci6n adicional en el siguiente enlace dentro de nuestra pagina web: https://www.cnio.es/es/privacidad/index .asp **LEGAL NOTICE**: This email and any attached files may contain protected information for the sole use of its intended recipient or addressee. Anyone other than the intended recipient or addressee is strictly prohibited from distributing , reproducing or transmitting the email and its contents in any way. If you receive this email in error, please notify the sender and delete the message. Pursuant to the provisions of EU Regulation 2016/679 regarding the protection of personal data, any personal information you provide through this emai l will be registered by the CNIO Foundation in order to deal with content of this email. Your personal data must be processed in order to be able to deal with the content and purpose of this message. Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Sent: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc:List DEPDIR-L<@mail.nih.gov>; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Sent : (b)(6) To : Subject : FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Sent : Friday, March 27, 2020 6 :11 PM To: NIAID OD AM <@niaid .nih .gov>; Subject : W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Sent : To: Subjec t : (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Sent : Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Sent : To : Subject : Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From : Billet , Courtney (NIH/NIAID) [E] Se nt : Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From : Billet, Courtney (NIH/NIAID) [E] Sent: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From : Routh, Jennifer (NIH/N IAID) [E) Sent : Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Sent: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Se nt: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subjec t : RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Sent: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc:Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From:Rout h, Jennifer (NIH/NIAID) [E] _______ Sent: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc : -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From:Routh, Jennifer (NIH/NIAID) [E] Sent: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From:Routh , Jennifer (NIH/NIAID) [E] Sent: Tuesday, March 24, 2020 7:48 PM To : O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc:Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From:O'Malley, Devin M. EOP/OVP Sent : Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Se nt : Tuesday, March 24, 2020 7 :34 PM To : Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Sent : Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To : Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Sent : To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it <@libero.it> Sent : Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici Oggetto : Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From:Conrad , Patricia (NIH/NIAID) IE] Sent: Saturday, March 28, 2020 7:28 AM (b)( '> To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From:Janet Tobias <@ikanamedia.com> Date : March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Sent: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Se nt: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject : NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Sent: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback <@ncbi.nlm. nih.gov> Sent: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Sent : To: Subjec t : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias <@ikanamedia .com> Sent: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To : Subjec t : Thanks,John! From: Burklow, John (NIH/OD) [E) -------Se nt : Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To : Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject : Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Sent: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe <@frame.media > Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe <@frame.media >wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Sent : To : Subjec t : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Sent : Friday, March 27, 2020 10:28 AM To : Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Sent: To: Cc: Subject : RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Se nt : Friday, March To : Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject : Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Se nt: Friday, March 27, 2020 11:24 AM To : Narasimhan, Sri Devi (ELS-CMA)<@cell.com> Cc: Fauci, Anthony (NIH/N IAID) [E] <@niaid.nih.gov> Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Sent: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Sent: Thursday, March 26, 2020 4:53 PM To : Narasimhan, Sri Devi (ELS-CMA) <@cell.com > Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA)<@cell.com > Sent: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Sent: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Sent : To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Sent: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Sent : To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To : Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent : Thursday, March 26, 2020 9:08 AM To : Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Sent: Wednesday, March 25, 2020 6:3 1 PM To : Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William <@apcoworldwide .com > Sent : Wednesday, March 25, 2020 4:24 PM To : Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subje ct: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Sent: Thursday, Ma rch 26, 2020 5:02 AM To : Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Sent : To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Sent : Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject : Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Sent : To : Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore <@health.ucsd.edu> Sent: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n <@health Subject : Re: George Church interview Date: March 24, 2020 at 12:09:20 PM PDT To: Jon Cohen <@aaas.org> NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen <@aaas.org> wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore <@ucsd.edu> wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Sent : To: Subjec t : Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Sent: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:DELFRAISSYJean-franco is Sent: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Sent: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Sent: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subjec t : RE:wi th love fro m Italy From: Sent : Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Se nt : Wed nesday, March 25, 2020 7:58 AM To : Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From : Jon LaPook ______ __,(b'"" )..,. (6) = Sent: Tuesday, March 24 , 2020 2 :17 PM To : Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subj ec t: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Sen t: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subjec t: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Sent: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Sent : Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Sent : To : Subjec t : From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Se nt : Tuesday, March 24 , 2020 8 :59 PM To : Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Sent : To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Sent : Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From:Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Sent : Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Sent: Monday, March 23, 2020 10:45 PM To : Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able to: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From : Sent : To : Subject : Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : RYAN, Michae l J. (b)(6) Sent : Tuesday, March 24, 2020 10:59 AM To : SHOC<@who .int> ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives <@reso lvetosavelives .org>; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc:SHOC<@who.int>; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From : Raphael De Montferrand <@rttv .fr> Sent: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject : FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIA ID) [E] (b)(6) Sent : Tuesday, March 24, 2020 10:16 AM To : NIAID OCGR Leg <@n iaid .nih .gov>; NIAID COGCORE<@mail.nih.gov> Subj ect: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Sent: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Sent: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC <@everb ri dge.net > Sent: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Sent: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc:Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen <@washpost.com > Sent: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley <@washpost.com > Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Sent : To: Subjec t : (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Sent: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams <@wamu.org > Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" <@niaid.nih .gov> Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Sent: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Sent: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To : "ICDDIR-L@LIST.NIH.GOV " <@LIST.NIH .GOV> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Sent: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Sent: To : (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Sent: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Sent : To : Subject : Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From : Barry Albertson <@fannocreek .com> Sent : Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Sent: Monday, March23, 2020 9:49 AM To : 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Sent: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To : (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Sent : To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Sent: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Sent : Sunday, Marc h 22, 2020 9:31 PM To : Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Sent : To : Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Sent: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up to: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up to: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Sent : Saturday , March 21, 20 20 5 :25 PM To : Young, Howard (NIH/NCI) [E]________ Subje ct: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Sent : To : Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Sent: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From : Sent : To : Subject : Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Sent : (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject : Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To : Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner <@jamanetwork.org> Sent: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani <@jamanetwork .org> Cc: Edward Livingston <@jamanetwork .org> Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner <@jamanetwo rk.org>, Tony Fauci 6b , Preeti Malan i <@med.um ich.edu>, Eli Perencevich , Phil Fontanarosa <@jamanetwork.o rg> Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner <@jamanetwo rk.org> Sent: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Sent: To : Subject : ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Se nt : Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Sent : Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject : Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Sent: To : Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Sent: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject : FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Sent : For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Sent : Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject : Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Karen Backman (b)(6) Sent: Monday, March 23, 2020 8:53 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Subj ect : Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Sent : To : Subj ect : At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Sent: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Sent : (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To : David Rubenstein Subjec t: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From : Se nt: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From : Marston, Hilary (NIH/N IAID) (E] (b)(6) Sen t : Sunday, March 22, 2020 7:10 PM To : Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject : Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subj e ct: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From : Jo n LaPook ,.....___ _,(""' b),,.., (6) => Sent : Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Sent: To : Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G <@nytimes.com> Sent: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject : big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Sent : Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject : Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Sent: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To : Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Sent: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject : Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject : RE: Dr. Fauci: Senate Draft COVID-19 Supp Sent : (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Sent : Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subj ect : Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Sent: To: Subject : Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To : Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Sent: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Sent: To : Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Sent : Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To : Cc: Subject : ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To : Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject:Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Sent: To: Subject : Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Dat e: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Sent : (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Sent : To : Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From:John Monahan <@georgetown.edu> Sent: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Sent: (b)(6) To : Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Sent: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Sent: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject : Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) <@uidaho .edu> wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Sent : (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To : Subject : Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Sent: To: Subject : (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re <@health.ucsd .edu> wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Sent : (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" <@sriramachandra .edu.in> Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Sent : (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To : Subject : Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna <@ho lycross .bc.ca>wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Sent: Sat, 21 Mar 2020 07 :35:58 -040 0 To : DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Sent: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D <@email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Sent : To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From:Priscilla Kelly <@aaas.org> Sent : Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Sent: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To : Subject : Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Se nt : Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject : FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date : Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Se nt : Friday, March 6, 2020 8:46 PM To : Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject : Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Sent : (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From:Collins, Francis (NIH/OD) [E] (b)(6)> Sent: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Sent: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject : RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Sent : Thursday, March 19, 2020 9:31 PM To : Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc:Tabak, Lawrence (NIH/OD) [E] (b)(6) Subjec t : COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard <@rwjf .org> Sent: Thursday, March 19, 2020 3:59 PM To : Fauci, Anthony (NIH/NIAID) [E] <-----Subject : Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Sent : To: Cc: Subject : - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Sent : Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject : FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Sent : Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier Elemento : Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject : [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Sent: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To : (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From : Cb)(6J.> Sent : Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject : Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Sent: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To : Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject : [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Sent : Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To : "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Sent : Wed nesday, Marc h 18, 2020 5 :09 PM Subject : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Sent : Thu, 19 Mar 2020 08:30:51 -0400 To : Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From : Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To : Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Sent: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To : Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject : FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Se nt : Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Sent: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To : Cc: Subject : Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila <@nyt imes .com > Sent: Wednesday, March 18, 2020 4:10:58 PM To : Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject : Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila <@nytimes .com > Sent: Wednesday, March 18, 2020 3:27 PM To : Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject : Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes .com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Sent: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila <@nytimes.com> Sent: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject : Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila <@nytim es.com > Sent: Wednesday, March 18, 2020 3:27 PM To : Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes.com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen <@b io- signal.com> Sent: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Sent: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila <@nyt imes.com> Sent : Wednesday, March 18, 2020 4:10:58 PM To : Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila <@nyt imes.com > Sent: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@ny t imes.com > wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Sent: To : Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Sent: Wednesday, March 18, 2020 8:16 PM ------~= To : Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Sent: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Se nt: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Sent: To : Subject : Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Sent : Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subje ct: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Sent : (b)(6) To : Subject : Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Sent: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Sent: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Sent: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Sent: To: Subject : (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Sent: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Sent: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Sent: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject : FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From:Lane, Cliff (NIH/NIAID) [E) Sent: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Sent: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Sent : To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject : RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Sent : Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject : Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Sent: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject : RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Sent: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Sent: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From:Collins, Francis (NIH/OD ) [E] Sent: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Sent: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject : RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Se nt: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From : Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Sent : To: Subj ect : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Sent : Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Sent : Wednesday, March 18, 2020 4:01 PM To : Fauci, Anthony (NIH/NIAID) [El Subject : Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : WW (b) (6) Sent: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To : Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject : Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Sent: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Sent: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To : Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From:Alexandra Flemming <@nature .com> Sent: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Sent: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey <@bio.org > Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = <@bio.org> --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Sent : (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias <@ikanamedia.com > Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias <@ikanamedia.com> Sent : Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Sent : To : Subject : Please respond. From : EDWARD EITZEN (b)(6) Se nt: Sunday, March 8, 2020 3:10 PM ~= To : Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject : Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Sent: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject : Please respond for me. -----Original Message ----From: Candace Gunn --------Sent : Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Sent : To : Subject : Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Sent: Saturday, March 7, 2020 5:27 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Sent : Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To : Lerner, Andrea (NIH/NIAID) [El Subject : FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From:Tabak, Lawrence (NIH/OD) [El Se nt: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From:John G. Boland Sent: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject : Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Sent: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subje ct: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From : Pardis Sabeti (b)(6) Se nt : Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject : Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date : Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From:Wi llick, Jason <@wsj.com> Sent : Monday, March 16, 2020 9:44 PM ------------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Sent: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailto: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Sent: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Sent: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Sent : Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Sent : Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Sent: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From:Monticone, Giulia (b)(6)> Sent: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Sent: To : Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Sent : Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Sent: Monday, Ma rch 16, 2020 3:19 PM To : Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE<@n iaid.nih.gov>; NIAID FOG<@niaid .nih .gov> Subject : Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Sent: To: Subject : _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Sent: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Sent: To: Subject: Please respond. From: PEAK (b) (6b Sent: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Sent: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Sent: Mo n, 16 Mar 2020 14:31:15 -0400 To : Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Sent : (b)(6) To : Subject : Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Sent : (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To : Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject : Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<@,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD T o: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Sent: To: Subject : Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Sent: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Sent : (b)(6) To : Subject : Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Sent: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Sent: To: Subject : Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Dat e: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Sent: (b)(6) To : Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Sent: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" <@FOXNEWS.COM> Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From : Baier, Bret <@FOXNEWS.COM> Sent : Friday, March 13, 2020 3:30 PM To: Koerber, Ashley <@FOXNEWS.COM>; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject : RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Sent: Friday, March 13, 2020 3:27 PM To : 'Conrad, Patricia (NIH/NIAID) [E]' Cc : Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret <@FOXNEWS.COM> Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley <@FOXNEWS.COM> Sent: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley <@FOXNEWS.COM> Sent: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subje ct: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley <@foxnews.com >wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 <@foxne ws.com >wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From : Koerber, Ashley Se nt: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject : Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Sent: To: Subject : Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject : FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Sent : Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Sent : Sunday, March 15, 2020 10:13 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject : ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Se nt: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject : Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Se nt: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subje ct : Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Sent: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From : Bertuzzi, Stefano Sent: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject : Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject : From: David Bardan (b)(6)> Sent: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc:Shriya Palekar <@tytocare .com> Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Sent: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To : "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Sent: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject : Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Sent: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson <@zrgpartners.com> Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Sent: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Sent: To: Subject : Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Sent: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject : Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Sent: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Sent: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson <@robinsonmanagementserv ice.com > wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Sent: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Sent: To: Subject : Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y <@howard.edu> wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Sent: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Sent: To: Subject : Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Sent: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To : Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones <@winning-newsmedia.com> wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Sent: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Sent: To: Subject : (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Sent : Sun, 15 Mar 2020 18:55:37 -0400 To : el Subject : Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Sent : (b)(6) To : Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject : Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Sent : (b)(6) To: Subject : Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Sent: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject : RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Se nt: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Sent: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject : Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Sent: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To : Subject : Please handle. ------------- From: Landrigan, David Sent: Sunday, March 15, 2020 1:44 PM To : Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Sent : To: Subject : This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Se nt : Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject : Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Dat e: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject : Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" <@turne r.com > Dat e: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject : [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Sent : Sun, 15 Mar 2020 13:30:08 -0400 To : Soumya Jayaraj Subject : Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Sent: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject : Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Sent: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian <@slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian <@slammiami.com> -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Sent: To: Subject : Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Sent: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject : Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq <@jsgroup.com.kw> wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Sent: To: Subject : Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Dat e: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Sent : To : Subject : Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From:Collins, Francis (NIH/OD) [E] Sent : Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject : Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Sent : To: Subject : Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Se nt: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject : Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From:Ramaswamy,Sriram Sent: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Sent: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Sent: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Sent: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To : Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson <@med.cornell.edu>wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Sent: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 <@columbi a.edu>; kathleen foley (b)(6); Carol Storey-Johnson <@med .corn ell .edu > Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Sent: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject : Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Sent : (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To : Subject : Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To : "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Sent: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Sent : (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Sent: To: Subject : Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Se nt : Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Sent : To : Subject : Thank you! From: Halula, Madelon (NIH/NIAID) [E] Sent : Monday, March 9, 2020 10:10 AM To : Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject : Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Sent: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Sent : (b)(6) To : Subject : Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From:Celia Lewis (b)(6)> sent: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Sent: To: Subject : Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Sent: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Sent: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Sent: To: Subject : William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Sent : Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Sent : To : Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Sent : Friday, March 13, 2020 8:23 PM To : Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Sent: To: Subject : Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----from : Alecia Siuta :.:-------(b ~)-(6) ~ Sent: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Sent: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To : Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Lynda Hayashi Sent : Thursd ay, March 12, 202010 :17 PM To : Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject : dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Sent : (b)(6) To : Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject : Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Sent : (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To : NIAID Public Inquir ies Subject : Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Dat e: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject : thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Sent: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To : Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Sent: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Sent : (b)(6) To : Subject : Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To : "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Sent: (b)(6) To : Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Sent: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To : Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Sent : Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subjec t: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From : Marston, Hilary (Nll-1/NIAID) [El Sent: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Sent : Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject : Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To : Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject : RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Sent : Tuesday, Ma rch 10, 2020 9 :54 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Sent: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Sent: Saturday, March 7, 2020 3:18 PM To : Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Sent : To: Subject : Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Sent: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject : Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Sent : Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject : FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Sent: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject : Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Sent: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From:Robert Danoff (b)(6) Sent: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From : Rose Marie Codling <@literacymatters .education> Sent : Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From : Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From : Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Se nt: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject : FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From : Collins, Francis (NIH/OD) (E] Se nt : Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject : RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Sent: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject : ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject : Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Se nt: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject : FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley <@researchamerica .org > Date : Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney <@resea rchamerica .org> Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From:Robert Tober (b) (6)> Sent: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Sent: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From:Jason Ressler (b)( Sent: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Sent : To: ---- ------ ,a-s-r:= Subject : (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Se nt : Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject : Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Sent : (b)(6) To : Subject : Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Sent : To: Cc: Subje ct: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah <@cbsnews.com> Sent: Thursday, March 12, 2020 9:12 AM To : Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] <@cbsnews.com> Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah <@cbsnews .com> Sent: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam <@cbsnews .com > Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From:Arthur Ammann Sent: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Sent: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Sent: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To : Subject : Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Sent: To: Subject : (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Sent: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Sent: To: Subject : Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From : Whit Clark ,,,_..-----= (b,.,. )""' (6) =Sent: Wednesday, March 11, 2020 7:39 AJ\'1 To : Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Sent: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Sent: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Sent: To: Subject : Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Dat e: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Sent: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Sent : To: Cc: Subje ct: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Sent: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu <@stanford.edu> Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" <@stanford.edu >, Amanda Chase <@sta nford.edu > Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Sent : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To : Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:David Knipe <@hms.harvard.edu> Sent: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Sent : Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Tue, 10 Mar 2020 17:46:08 +0000 To : Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Sent: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:1iiJ ~ (b)(6)> Sent: Tuesday, March 10, 2020 1:46 AM To : Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject : asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject : FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Se nt: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Sent : To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Sent: To: Subject : Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----from : Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Sent: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Sent : Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To : Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Sent: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To : Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Sent: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas<@bernstein.com > Date : Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From : Greg OKeeffe ------------ (b)(6) Sent: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas <@be rnste in.com > Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Sent : To : (b)(6) Subj ect : At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : CMS (b)(6) Se nt : Sunday, March 8, 2020 9:02 PM To : (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subj ect : Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: Fro m: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Dat e: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc:"Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject : Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Sent : To : Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From:Rita DiCasagrande Olsen Sent: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To : Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Se nt: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject : RE: COVID-19 From: Sent: To : Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Collins, Francis(NIH/OD) [E] Sent : Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject : RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Sent: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject:COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject : Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Sent: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Sent: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Sent : To : Subject : mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Sent : Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject : NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Sent : (b)(6) To : Subject : Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Sent: To: Subject : (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Sent: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To : Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas <@economist.com> Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas <@econ omist.com >wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Sent : (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Sent: To: Subject : Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date : March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Sent: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To:--------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From : Radostaw Sierpinski Date : March 9, 2020 at 6:42:08 AM EDT To : "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject : CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Sent : To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From:Greg Reilly <@theceoforumgroup .com> Sent: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Sent : To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Sent : Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date : Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject : Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Sent: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To : Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller <@cbc .ca> Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Sent: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject : Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Dat e: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Sent : (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Sent: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject : Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Sent: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Sent : To : Subject : Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke <@americamedia.org > Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Se nt: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Sent: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Sent : Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Alex Wolf, Esq. (212)717-2 510 <@wolf lawyer.com> Sent : Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject : Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Sent: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Sent : To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Sent: Monday , March 9, 2020 5:29 AM To : Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From : William Chin ________ (b_)~( = > Sent: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To : Subject : Thanks, Glenda! From: Glenda Gray <@mrc .ac.za> Se nt: Tuesday, March 3, 2020 9:37 AM _________ ..... To : Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subj ect : FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject : 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Sent : To: Subject : Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Sent : Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Sent : To : ---- Subject : Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Sent : Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject : FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date : Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject : RE:Thanks so much Sent: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Sent: Sunday . March 8. 2020 9:48 PM______ To : Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Sent: To : Subject : From: Clayton Conger Se nt : Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Se nt: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject : Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From : Hellmich, Helen Se nt: Sunday, March 8, 2020 5:52 PM To : Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject : can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Sent: Sunday, March 8, 2020 7:02 PM To : Fauci, Anthony {NIH/ NIAID) [E] Subje ct: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From : William Schiesser (b)( Sent : Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject : COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To : Subject : RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Sent : Sunday, Marc h 8, 2020 8:12 PM To : Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject : Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Sent : To: Subject : FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin <@hdltherapeutics.com> Sent : Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject : URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Dat e: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert <@steinmancommunications.com> Se nt : Sunday , March 8, 2020 7:59 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject : Please handle. From: Barb E Se nt: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject : RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From : Austin, Christopher (NIH/NCATS) [E] Sent : Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject : RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From : Collins, Francis (NIH/OD) [E]______ Sent : Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject : RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From : Collins, Francis (NIH/OD) [E] Sen t: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject : ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From : Sent : To : Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From : Greg Simon (b) ( > Se nt : Friday, March 6, 2020 7:22 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject : Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Dat e : Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Sent : To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject : FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject : FYI ________ ________ -------=-:--:= (b)__, (6)> From:IPJ::J~lli-1Sent : Sunday, March 8, 2020 9:58 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Sent : To : Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Se nt: Sunday, March 8, 2020 2:54 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From:Anthony Fauci (b)(6) Date : Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject : RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Sent : Sunday, March 8, 2020 11:17 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject : We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Sent: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To : Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Sent: Saturday, March 7, 2020 3:40 PM To : Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Sent: Sunday, March 8, 2020 10:13 AM To : Fauci, Anthony {NIH/NIAID) [E] Subje ct: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To : CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Sent: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Sent: Sun, 8 Mar 2020 09:59 :21 -0400 To : Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur <@bio.or g> Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur <@bio .org> Cc: Jenni fe r Alton <@pathwaypolicy .com>, Ellen Carlin (bH6) >, Amy Walker <@bio.org>, Grego1yFrank ---------<@bio.org> Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Sent: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Sent: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To : Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Sent : (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Sent: Saturday, March 7, 2020 4:09 PM To : Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Sent: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Sent : (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Sent: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Sent: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To : Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone <@scripps.edu> Sent: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Sent : Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From:Liz Cheney CbH6)> Sent: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject : Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Sent: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Sent : Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Sent : To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada <@elconfidencial.com> Sent : Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Sent : Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Sent: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Sent: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah <@bmc .org> Sent: Saturday, March 7, 2020 5:19 PM To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc:Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From : Fauci, Anthony (NIH/NIAID) [E) Sent: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Sent: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc:secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject:One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" <@scientekpower.com> To: (b)(6) Reply-To: <@scientekpower .com> Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To : (b) (6)' Cc: RE:NSCinquiry on treatment study Subjec t: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Sen t : Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject : NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject : We are pursu ing th is idea. From: Gregory Klomp Se nt: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Sent: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To : Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Sent : To: Cc: -------- Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Sent : Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Sent: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Sent: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Sent: To: Subject: Please have someone respond. From: Leonard Trudell Sent: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To : Subject : Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Sent: Saturday, March 7, 2020 11:56 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Sent: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Sent: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Sent: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To : Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Sent : Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Sent: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Sent : (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From:Elizabeth Stevens Sent : Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Sent: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To : FW: Subject : ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Se nt : Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Sent: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From:Ann Job (b)(6)> Sent : Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Sent: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Sent: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From:Anderson, Jennifer (NIH/NIAID) [E] Sent: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From : Lipkin, Ian W. _________ Cb _> _<_, Sent: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From : L ipkin, Ian W. _________ Cb _)_(_. 6l> Sent: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Sent : Friday, March 6, 2020 6:18 PM Subject : JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Sent: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Sent: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Sent: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Sent: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Sent : Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Se nt: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject : RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Sent: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Sent: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject : FW: Developing Immunity to SARS-CoV-2and lvlg From: Sent : Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm <@kammconsultinginc.com> Sent : Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To : Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From : Corey MD, Larry Sent: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Se nt : Thursday, March 5, 2020 11:19 PM Subject : NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) <@msnbc .com> Sent : Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject : Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Sent : Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To : Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Sent : Friday, March 6, 2020 3:46 AM -------=:-:-=, To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Sent: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From:Corey MD, Larry Sent: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Sent: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Sent : Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject : FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Sent : Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject : SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject : FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To : fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Se nt: Wednesday, Marc h 4, 2020 4:27 PM Subject : medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From:James Krellensteih sent: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From : Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject : Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From : Pavletic, Steven (NIH/NCI) [E) (b)(6)> Se nt: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From : Brian Betts (b)(6)> Sent : Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject : Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Sent : To: Subject : Let us discuss. From: Stephen Morrison <@csis .org> Se nt : Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman <@csis.org> Subject : Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison <@cs is.org > wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Sent : F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To : Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Sent: Thursday, March 5, 2020 7:49 AM To : Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From : Phillips , Kyra <@abc.com> Sent: Thursday, March 5, 2020 9:30 AM To : Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra <@a bc.com > > Sent: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Sent: To: Subject : (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Sent: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Hurst, Natalie R. EOP/OVP (b)(6) Sent: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Sent: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Sent: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To : Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Sent : For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Sent: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Sent : To : Cc: (NIH/NIAID) [E] Subject : Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To : Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject : T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date : Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Sent: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To : Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc:Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date : February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Sent: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From : Carte r Mecher NIH-001470 Sent : Friday, February 21, 2020 6:52 PM To : Richard Hatchett ; Dr. Eva K l ee Cc : Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Sent: Friday , February 21, 2020 1:59 PM To : Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From : Carter Mecher Sen t: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject : RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From : Carter Meche r Se nt : Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Sent : Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Sent: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From : Carter Mecher Sent : Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Sent: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From : Carte r M eche r Sent : Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Sent : Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subjec t: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Sent : Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Sen t : Thursday, February 20, 2020 11:00 AM To : Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Sent: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Sent: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc : Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Sent: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Sent: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From : Carter Mecher Sent : Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Sent : Wednesday, February 19, 2020 4:45 PM Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From : (b)( Sent : Wednesday, February 19, 2020 2:36 PM To : Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From : Carter Mecher Sent : Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Sent : Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Sent: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Sent: Wednesday, February 19, 2020 6:06 AM To : Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Sent: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc:Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Sent: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Sent: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Sent: Tuesday , February 18, 2020 1:06 PM To : Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Sent: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Sent: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Sent: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject : RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Sent: Tuesday, Februaiy 18, 2020 10:45 AM To : Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From:Carter Mec her (b)(6) NIH-001527 Sent: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Sent: Tues day, Feb ruary 18, 2020 10: 15 AM To : Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Sent: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Sent: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Sent: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc:C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Sent: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Sent: Monday, February 17, 2020 4:51 PM To : Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Sent: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Sent: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Sent: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Sent: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Sent: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From : Cart er Mecher Sent: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Sent: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Sent: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Sent: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Sent: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Sent: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Sent: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Sent: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject : FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date : Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To : "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc:"Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subje ct: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject : Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Se nt : Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject : Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Sent: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subje ct : Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From : "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date : February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From : Grigsby, Garrett (HHS/OS/OGA) (b)(6) Sent : Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject : Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date : February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Se nt: Friday, Februa ry 21, 2020 5:53 AM To : Fauci, Anthony (NIH/N IAID) [E] Subj ect : Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Thu, 20 Feb 2020 21:26:05 +0000 To : Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From : Kadlec, Robert (OS/ASPR/10) < (b)( > Sent : Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject : HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject : RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Sent : HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Se nt: Wednesday, February 19, 2020 10:54 PM To : Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject : RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Sent : Wednesday, February 19, 2020 10 :06 PM To : Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject : RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Sent: Wed nesday, February 19, 2020 10 :02 PM To : Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From : Sent : To : Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From : Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subj ect : Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From : "Hall, Bill (HHS/ASPA)" (b)(6)> Dat e: Tuesday, February 18, 2020 at 4:52:06 PM Subj ect : FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List <@LISTSERV .CDC.GOV> On Beha lf Of Media@cdc .gov (CDC) Se nt : Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subje ct : CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Sent : To : Bee: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Sent : Monday, February 17, 2020 2:56 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date : February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Sent: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject : RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Sent : Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen <@was hpost .com> Se nt: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject : WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To : Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject : RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Sent : Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Sent : Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject : Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Sent : Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject : FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Sent : Saturda y, February 22, 2020 10:52 AM Subj ect : Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Se nt : Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject : COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject : RE: Infectious d isease advice for NSO Asia tour Sent : Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Se nt : Friday, February 21, 2020 6:31 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject : Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Se nt: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc:Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Sent: Friday, February 21, 2020 5:21 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F.<@Kennedy-Center .org> Sent: Thursday, February 20, 2020 5:59 PM To : Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary <@Kennedy-Center .org> Subject : Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Sent: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To : Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul <@thaiembdc.org> Sent: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc:Chuliepote lsarankura Na Ayudhaya <@thaiembdc .org> Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Redfield, Robert R. (CDC/OD) Sent : Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject : Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Sent: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject : Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Sent: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Sent: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject : Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To : Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject : RE: COVID-19 messaging From: Sent : (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Sen t : Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject : Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date : Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject : RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Sent : Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject : COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Sent : To: Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Sent: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject : FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject : Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From : "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From : Schmitt, James(NIH/OD/ORS) [El Sent: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc:Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Sent : Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc : Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject : COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Sent: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc : Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From:Gary K. Schoolnik (b)(6)> Sent: Friday, February 14, 2020 6:27 PM -----~~ To : Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject : Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Sent: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To : Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <@vox.com>wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Sent: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Sent: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject : FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Sent: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Clayton, Janine (NIH/OD) [El Sent : Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Sent: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject : 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Sent : To: Subj ect : (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From : Steven Lehrer Sent : Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject : ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Sent : Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject : for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Sent : Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject : (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Sent: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Sent : Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject : _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Sent : To : Subj ect : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Sent : Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject : RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Sent: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From : Fried, Linda P . (b)(6) Sent : Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject : Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To : Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Sent : Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject : A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject : FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Se nt: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM <@niaid.nih .gov> Subject : FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From : Sent : To : Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling <@thedocumentarygroup .com> Se nt : Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE DATE: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From:Calio, Nicholas <@airlines.org> Sent: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To : Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Sent: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To : Fauci, Anthony (NIH/NIAID) [El --------- Subject : FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Sent : Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject : Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Sent: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Sent: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From : Banner, Jon {PEP} (b)(6)> Se nt: Tuesday, February 11, 2020 9:44 PM To : (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject : Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Sent : To : Subject : Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Sent : Thursday, February 13, 2020 12:45 PM To : Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject : Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To : Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject : RE:COVID-19 vacc ine development From: Sent : Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From : Stoffels, Paul [JJCUS] Sent : Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc : Riccobene, Kim [JJCUS) Subject : COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From:Selgrade, Sara (NIH/NIA ID) [El Sent: Wed nesday, February 12, 2020 3:16 PM To : Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc:NIAID OCGR Leg <@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Sent : (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To : Subject : John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) <@bloomb erg .net>wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From : John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To : (b)(6) Sub j ect : RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From : a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To : J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Sub jec t : RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) <@bloomberg .net> Sent : Monday , February 3, 2020 8 :18 AM To : Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subje ct: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Sent : (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To : Daniel Lucey Subject : Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Sent: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From : Conrad, Patricia (NIH/NIAJD) [E) Sent : Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci <@businesscouncil.com> Sent: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc:Adrienne Ball <@businesscoun cil.com >; Gillian Auger <@bus inesscounc il.com > Subject : Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci <@businesscouncil.com> wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From : Marlene Colucci <@businesscouncil.com > Sent: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject : Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg <@eng.us> Sent: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov> Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg <@ama -assn.org> Sent: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject : AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Sent: To : Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Sent: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject : 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Wed, 12 Feb 2020 00:05:00 +0000 To : Subject : Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Sent : Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM <@niaid.nih .gov> Subject : take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Sent : Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM <@niaid.nih .gov> Subject : this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison <@csis.org> Sent : Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll <@csis.org>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Sent : To : Subject : Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman <@pl et te r .com> Se nt : Tuesday, Februa ry 11, 2020 11:00 AM To : Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject : Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ <@stimes.cn> Sent: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal <@mai lonline .com> Sent: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject : RE: W HO meeti ng Sent: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= from : Nabel, Gary /US Sent: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Sent: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Sent: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Sent: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To : Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Sent: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Sent: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero <@pazienti.it> Sent: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza <@pazienti.it> Subject : Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Se nt: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject : Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : (b)( · Sent: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From : Sent : To: Subj ect : OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Sent : Tuesday, February 11, 2020 7:37 AM To : Fauci, Anthony (NIH/NIAID) [El Subj ect : Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" <@wtop .com > Dat e: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject : WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To : Lisa Monaco Subject : RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Sent: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Sent : To : Cc: (NIH/NIAID) [E];Lerner, Subject : Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From : Routh, Jennifer (NIH/NIAID) [E] Sen t : Monday, February 10, 2020 4:07 PM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Sent : Monday, February 10, 2020 2:37 PM Subject : Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Sent : To : Subject : Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Se nt: Monday, February 10, 2020 3:02 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses <@usasiainstitute .org> Sent : Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Sent : To: Subject : Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine <@trilateral.org> Sent : Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig <@tr ilateral.org> Subject : Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Strauss, Eric M.<@abc.com> Sent: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From : Jon LaPook ,.::;....---~ (b ~)~(6) => Sent: Monday , febrnary 10, 2020 10:08 AM To : Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan <@cbsnews.com > ; Jay Shaylor <@cbsnews.com > Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim <@cnn .com > Sent: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From:Lati ka Chugh {WION) <@zeemedia.esselgroup.com> Sent: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc:Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) <@zeemedia.esselgroup (W 10 .com> Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Sent : Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) <@zeemed ia.esselgroup.com >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) <@zeemed ia.esselgroup .com > Sent: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <@zeemed ia.esselgro up.com> Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Sent : Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) <@zeemed ia.esselgrou p.com >; KUMAR SUNNY <@zeemedia.esselgroup.com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) <@zeemed ia.esselgroup.com > Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) <@zeemed ia.esselgrou p.com > Sent : Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemed ia.esselgroup. com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From:Awwad, David (NIH/NIAID) [CJ Cb)( Sent: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) <@zeemedia.esselgroup.com> Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject : RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) <@zeemedia.esselgroup.com> Sent: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Sent : Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To : Latika Chugh (WION) <@zeemed ia.esselgroup .co m> Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) <@zeemedia .esselgr oup.com > wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgro up .com > Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subje ct : FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) <@zeemed ia.esselgroup.com > Sent: Tuesday , February 4, 2020 5:15 AM To : Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations<@zeemedia.esselgroup.com> Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Se nt: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" <@turner.com > Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " <@turner .com> Subject : CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Sent: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle <@turne r.com> Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle <@turner .com > wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Sent : Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle <@turner.com > Cc : Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle <@tu rner .com> wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle <@tu rner .com> Subject : Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle <@turne r.com > Sent: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Sent : To: Subject : Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Sent: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subje ct: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Sent: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject : Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To : Folkers, Greg (NIH/NIAID) [E] Subject : RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 1:13 PM Subject : lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From : Liz Szabo <@kff.org> Se nt : Saturday, February 8, 2020 7:21 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To : Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Sent : Sunday, February 9, 2020 12:46 PM -----~~ To : Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject : NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Se nt: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" <@turner.com > Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject : CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To : Subject : If we can do this, I w ou ld be happy to. From:Varon, Sophie <@turner .com> Sent: Sunday, February 9, 2020 12:30 PM To : Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) <@turner .com> Se nt : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Sent: 09 February 2020 16:15 To: Hynds, Joanna (NE) <@turner .com> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <@turner .com> wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: 09 February 2020 14:26 To: Hynds, Joanna (NE) <@turner .com > Cc:Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner .com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) <@turner .com > wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Sent: 09 February 2020 13 :33 To: Hynds, Joanna (NE) <@turner.com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner.com > wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Sent: 09 February 2020 13:00 To: Hynds, Joanna (NE) <@turner .com > Subje ct: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Dat e: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From : "Hynds, Joanna (NE)" <@turner .com > Date : February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" <@turner.c om >, "Lovejoy, Hannah NIH-00203 1 (NE)" <@turn er .com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject : RE: HEART WRENCHINGQUESTION! Will Sent : The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Sent: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Sent: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From:autotell I Sent: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Sent: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From:Stover, Kathy (NIH/NIAID) [E] (b)(6)> Sent: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Sent : Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject : FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve<@cowen .com> Se nt: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil <@cowen.com>; Nedelcovych, Michael <@cowen.com> Subject : Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 9:45 AM Subject : Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Sent: (b)(6) To : Cc: Subject : Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" <@tumer.com >, "Lovejoy , Hannah (NE)" <@tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Sent: 09 February 2020 14:42 To: Hynds, Joanna (NE) <@turner.com> Cc:Pfeifer, Hazel <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) <@turne r.com>wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: 09 February 2020 14:35 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@t urner .com >; Lovejoy, Hannah (NE) <@turner .com >; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) <@turne r. com>wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From : Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Se nt: 09 February 2020 13:33 To : Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner .com>; Lovejoy, Hannah (NE) <@turne r.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner .com >wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent : 09 February 2020 13:00 To:H ynd~Joanna(NE) <@turner .com > Subject : Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From : " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date : February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject : Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date : February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To : Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject : RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Sent: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) <@turner.com> Se nt : Sunday, February 9, 2020 6:06 AM To : Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Sent : (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To : Subject : Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@tumer.com> Dat e: February 9, 2020 at 6:06:15 AM EST ------~~ To : "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" <@turner.com > , "Lovejoy , Hannah (NE)" <@turner.com > Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias <@ikanamed ia.com> Sent: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Se nt: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject : Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To : Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From : Robinson, Sae <@wtop.com> Se nt : Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From : Robinson, Sae <@wtop.com > Sent : Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject : Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal <@wtop .com> wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date : February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" <@wtop .com> Subject : RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal <@wtop .com > Sent: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Sent : To: Cc: Subject : desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From:Awwad, David (NIH/NIAID) [C) Sent: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM <@niaid .nih .gov> Subject : Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subject : FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Se nt: Saturday, February 8, 2020 11:34 AM Subject : Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From : Griffin, Janelle <@turner.com> Sent : Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject : CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Sent : To: Subject : I am OK with their coming to the house w ithout a truck. I will call you in the AM. From:Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject : Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" <@FOXNEWS.COM> Date : February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra <@FOXNEWS.COM> Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra <@foxnews.com > wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" DATE: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Sent : To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Sent: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Sent : Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Sent : (b)(6) To : Subject : RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Se nt : Friday, February 7, 2020 9:03 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date : Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Sent: To: Subject : Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Sent: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Sent : To : Subject : Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From : Ian Ingram <@medpagetoday.com> Sent : Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject : Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To : Cc: Subject : Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano <@buzzfeed .com> Sent : Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject : BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Sent : To: Subject : Very interesting! ! From:Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject : ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From : davidwillman (b)(6) Sent : Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject : Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Sent : To: Subject : Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda <@gannett.com> Se nt: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject : Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject : John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From : Mellors, John W (b) (6) Sent: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject : Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner <@jamanetwork.org> Sent: Thursday, February 6, 2020 6:39 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor <@ama-assn .org > Date : Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork.org >, Annette Flanagin <@jamanetwork.o rg>, Michae l Berkwits <@ama-assn.org >, Brian Shields <@ama -assn.o rg>, Sean O'Donnell NIH-002097 <@ama-assn.erg> Subject : Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner <@jamanetwork.org> Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r <@ama - assn.org> Date : Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork .org >, Annette Flanag in <@jamanetwork.org >, Michae l Berkwits <@jamanetwork.org >, Tom Easley <@ama -assn.org >, Brian Shields <@ama -assn.org >, Sean O'Donnell <@ama-assn .org > Subje ct: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Sent: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To : Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Sent: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Sent: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Sent : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To : RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Sent : Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Sent: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To : Cc: Patricia {NIH/NIAID) [El Subject : RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Sent: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To : Fauci, Anthony {NIH/NIAID) [El Subject : FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Sent : Wed nesday, February 5, 2020 10 :55 PM To : Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject : Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Sent : Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject : RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Sent : Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject : Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Sent : Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject : Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Sent : To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Sent : Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date : Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb <@gmai l.com> wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subjec t: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner <@jamanetwork .org> Sent: Wednesday , February 5, 2020 6:37 AM To : Fauci , Anthony (NTTI/NIAID) [E] Cc : Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Sent : Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner <@jamanetwork.org> Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner <@jamanetwork.org> Sent: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---Fro m: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Sent: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner <@jama netwo rk.org> Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner <@jamanetvvork .org> Sent: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Sent: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner <@jamanetwork.org >; Phil Fontanarosa <@jamanetwork.org > Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Sent: To : ----------- Subject: Please t ake care of this. From:Larry Schlesinger ----------Sent: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Sent: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth <@turner.com> Se nt: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject : treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Subject : FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Sent : Please handle. From : stanley satz (b)(6) Sent : Wednesday, February 5, 2020 7:20 PM To : Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject : Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Sent: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Sent: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) To : Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From:Mak, Tak (b)(6) Sent : Wednesday, February 5, 2020 7:30 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc:Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Sen t: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject : Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date : Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From : Collins, Francis (NIH/OD) [E] (b)(6) Sent : Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From : Jeremy Farrar (b)(6) Sent: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Sent: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject : FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Sent: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons <@t hehill .com> Sent : Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject : note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Sent: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq <@ntv.ru> Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee <@bbc.co.uk> Sent : Wednesday, February 5, 2020 8:21 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Sent : Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject : Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date : Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" <@mail.nih.gov>, "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject : Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Sent: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject : RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From : Friedel, Laura (Appropriations) Sent: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subje ct: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Sent : Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Sent: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Sent: Thursda y, February 13, 2020 1:31 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Sent: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Sent: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Wednesday, February 5, 2020 3:43 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject : RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Sent : Sunday, February 2, 2020 6:11 PM To : Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject : RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Sent : Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject : RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject : RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Sent : Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject : Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Sent : Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject : Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Sent : Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To : (b)(6) Subj ect : FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Sent: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Sent: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Sent: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To : Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Sent: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) <@HHS.GOV> Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject : FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Sent : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Sent : Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Sent : Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subjec t : RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Sent : Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject : FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Sent : Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From:SCHWARTLANDER,Bernhard F. Sent: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Sent: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject : WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold From : Sent : (b) (5) From : Shapiro, Neil {NIH/OD) [El (b)(6) Sen t : Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From : Collins, Francis (NIH/OD) [El (b)(6) Se nt: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From : Shapiro, Neil {NIH/OD) [E] Sent: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc:Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject : FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Se nt : Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Sen t : Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From : Malliou , Ekaterini (OS/10S) (b)(6)> Sent: Thursday, February 6, 2020 2:25 PM To : Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10<@hhs .gov>; ASPRExec Sec (OS/ASPR)<@hhs .gov> Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject : Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Sent : (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Sent: Thursday, February 6, 2020 4:12 PM To : Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas <@t heat lant ic.com > Sent: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Sent: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Sent: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Wednesday, February 5, 2020 3:43 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject : RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Sent : Sunday, February 2, 2020 6:11 PM To : Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject : RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Sent : Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject : RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject : RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Sent : Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject : Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Sent : Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject : Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject : Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Sent : Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sen t : Thursday, February 6, 2020 7:31 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Dat e: Thursday, February 6, 2020 at 1:23:26 AM To : "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <@hhs .gov > Subject : For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" <@hhs.gov > Subject : For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To : Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Sent: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > f rom: Lamourelle , Gabrielle (HHS/OS/OGA) Sent: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Sent: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral <@hhs.gov > Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Sent: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral <@hhs.gov > Subje ct: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Sent : To : Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From:Kerr, Lawrence (HHS/0S/OGA) Sent : Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Sent : (b)(6) To : Subject : Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Sent : Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To : Subject : Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. <@nejm.org>wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From : "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@ne j m.org> --------~= Cc:"Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject : RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From : "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To : "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org > Sent: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subje ct: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Sent : (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To : Subject : Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. <@nejm.org >wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Dat e: Tuesday, February 4, 2020 at 7:06 PM To : "Baden, Lindsey, M .D." <@nejm.org> Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject : RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. <@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.o rg> Sent: Tuesday, February 4, 2020 12:31 PM To : Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject : favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Sent : To: Subje ct: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY <@ahaber .com .tr> _______ --------=-:-= Sent: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Sent : Wednesday, February 5, 2020 2:58 AM ------------- To : Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subj ec t : Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Sent : To : Cc: Subje ct: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Sent: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject : RE:Coronavirus From: Sent : To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Sent : Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Se nt : Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject : RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Sent: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From : Shapiro, Neil (NIH/OD) [E] Sent: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From : Collins, Francis (NIH/OD) [E] (b)(6) Sent: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject : RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Sent: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject : Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date : Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject : RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci <@businesscouncil.com> Se nt: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein <@carly le.com> Subject : Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Sent : To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani <@ipsos.com> Sent : Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject : Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE:for review: responses for Elemental news site (not urgent) Sent : To: Cc: I made some modifications. You can send it. Th anks. From:Routh, Jennifer (NIH/NIAID) [E) (b)( Sent: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Sent: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To : Subject : Please handle. -----Original Message----From: Jon M (b) (61 Sent: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From : Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Se nt : Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From:Fleisher, Thomas (NIH/CC/OLM) (V) Sent: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Sent: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Sent: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From:Sylvia Burwell Sent : Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject : A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From:Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Rattaphol Onsanit <@v oanews.com > Sent: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To : Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject : FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg (NIH/N IAID) [E) -------Sent : Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject : WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Sent : Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . Photo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From : Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subj ect : RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Baden, Lindsey, M.D.<@nejm.org> Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subj ect : Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) Fro m: "Fauci, Anthony (NIH/ NIAID) [E]" Date : Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm.o rg> Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject : RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.<@ne jm.org> Se nt: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Sent: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject : Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From : Baden, Lindsey, M .D. <@nejm .org > Sent : Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject : Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From : "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@ne jm.or g> Sent: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To : Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Adam Miller <@cbc.ca> Sent : Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject : Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Sent: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject : Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. <@nejm .org> Sent : Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject : favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Sent : To: Subject : Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Sent : Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject : Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From : Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subj ect : FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Sent: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Tue, 4 Feb 2020 14:32:42 +0000 To : Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner <@jamanetwork.org> Sent : Tuesday, February 4, 2020 9 :19 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Sent : Tuesday, February 04, 2020 7:23 AM To : Annette Flanagin <@jamanet w ork .org>; Christiansen, Stacy <@jama network .o rg>; Demetrios Kyriacou <@i amanetwo rk .o rg>; Edward Livingston CbH6>>; Fontanaros, Phil <@jama-archives.org >; GoIub, Robert <@jama-a rchives.org>; Gregory Curfman --------------- NIH-002241 <@jama-archives.org ; Jody Zylke <@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits <@jamanetwork .org>; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <@jamanetwork.o rg>; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub <@jamanetwo rk.org>; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject : Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Sent: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ <@niaid.nih .gov> Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) <@n iaid .n i h,gov > Cc: Haskins, Melinda (NIH/NIAID) [E] Subject : RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Haskins, Melinda (NIH/NIAID) [E] Subject : Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamed ia.com > Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Sent: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias <@ikanamedia .com> wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Sent: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Sent: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject : Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Sent : Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject : Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Sent: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To : Fauci, Anthony (NIH/NIAID) [E) Subject : 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From:Latika Chugh {WION) <@zeemedia.esselgroup.com> Sent: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc:Wion Guest Relations <@zeemedia.esselgroup.com> Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To : Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject : Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Sent : Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To : Fauci, Anthony (NIH/NIAID) [E] Subject : Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Sent: To : Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Sent : Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From:Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Sent: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Sent: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Sent : Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Sent: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Sent: To : Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Sent: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] <@niaid .nih .gov> Subject : Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Sent: To: Subject : Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Sent: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From : Katz , Ruth <@aspenin stitute.org> Sent: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Sent: Monday, February 3, 2020 11:57 AM To: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth <@aspenin stitute.org> Sent : Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth <@aspeninstitut e.org> -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Sent: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth <@aspeninstitute.org > Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth <@aspenin stitute.org > Sent: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth <@aspenin stitute.org > Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth <@aspeninst itute.org >> Sent : Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth <@aspen institu te.org >> Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org <@aspen insti tute.org > 202-736-5827 NIH-002267 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Sent: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject : coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Sent : Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle <@th irteen.org> Sent : Friday, January 31, 2020 2:20 PM To : Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject : PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <@bloomberg .net > Sent: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From : Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subj ect: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From : Walensky, Loren D.,M.D .,Ph .D. Sent : Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subj ect : RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From : Glimcher, Laurie,M.D . --------------- Se nt: Sunday, February 2, 2020 9:33 PM To : Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject : Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject : Wuhan nCoV Inhibitors Date : January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica <@ansa.it> Sent : Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From:Joe Palca <@npr.org> Sent: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject : FW: Coronav irus vaccine ------- (b)( From:Joe Palea Sent: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject : RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Sent: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject : Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Sent: To: Subject : Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Sent: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Sent: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject : Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject : Wuhan nCoV Inhibitors Date : January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Sent : Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc : Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Sent : Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To : Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Sent: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Sent: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Sent: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From : Del Rio, Carlos 4 Cb>< ~> Sent: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Sent: Sunday, February 2, 2020 2:00 PM To : Fauci, Anthony {NIH/ NIAID) [E] Subje ct: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Subject : FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Sent : Please handle. From: Robert Jay Rowen (b)( Sent : Sunday, February 2, 2020 4:24 PM To : Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Sent : Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject : RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Sent : Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Sent : Saturday, February 1, 2020 9:02 PM To: NIAID OD AM <@niaid.n ih.gov> Subject : Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To : Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject : RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From : Sent : I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From : Routh, Jennifer (NIH/N IAID) [E] CbH Se nt : Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject : Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From : Rafael C. R. (b) (6)> Sent : Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From:Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Sent: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject : Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From : Sent : To: Subject : Geeeez --------- From : Billet, Courtney (NIH/NIAID) [E] Se nt: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject : Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From : " M ascola, John (NIH/VRC) [E]" Date : Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject : RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Sent : Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject : RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Sent : Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject : FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From : lssam AHMED <@afp.com > Sent: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject : Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Sent: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Sent : Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject : Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date : Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subje ct: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From : Jeremy Farrar Sent : Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc:Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From : Jeremy Farrar (b)(6) Sent: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject : RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From : Jeremy Farrar (b)(6) Se nt : Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject : Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" CC: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc:"Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject : My pleasure! From: Goldner, Shannah (NBCUniversal) <@nbcuni.com> Se nt: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject : Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Se nt: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) <@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc : Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject : [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) <@n bcun i .com> wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From : Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Sent: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Subject : [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Se nt: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject : RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Sent: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject : [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject : Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Sent: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject : [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) <@nbcuni. com > Sent: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Sent : Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject : RE: Inquiry and possible pone call To : ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From : Daley,George Q. Se nt: Sunday, February 2, 2020 10:32 AM To : Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject : Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Sent : Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Sent: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject : FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Sent: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From : Lorsch, Jon (NIH/NIGMS) [E] Sent: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Sent: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Sent : To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject : More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Se nt: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Sent : To: Subject : Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Se nt : Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject : Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Sent : To : Subje ct : Please handle. From: Jingyue Ju (b)(6) Sent : Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To : Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subje ct : Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From : Arnold Manto (b) ( > Sent : Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Se nt : Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Sent : To : Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From:Marlene Colucci <@businesscouncil.com> Sent: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein <@carlyle .com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From:Morens, David (NIH/NIAID) [E] Sent: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Sent : Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Sent : Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Sent : To: Subject : (b) (4) Please handle. From: Hong Cai (b)(6) Sent : Saturday, February 1, 2020 5:33 PM To: WRB Gmail <@gmail.com>; Fauci, Anthony (NIH/NIAID) [E] Subject : Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date : Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Se nt: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date : Saturday, 1 Februa ry 2020 at 20:50 To : Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject : Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject : Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From : Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To : Jere my Farrar CbH6J> Cc:"Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From : Jeremy Farrar CbH6J> Dat e: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To : Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Se nt: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject : FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Sent : To: Subject : Yes From: Jeremy Farrar (b)(6) Se nt : Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject : Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From:Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Sent : To : Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From:Albert Rizzo Sent: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc:Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject : Pleasehandle. From:Tatsch, Fernando Franciosi (b)(6)> Sent: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject : RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From:Tatsch, Fernando Franciosi Sent : Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Sent: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date : January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From : " Lieberm an, Marc E." <@cbsnews.com> Date : January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject : 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Sent : To: Subject : No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Sent : Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Sent : Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject : ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date : Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" <@n iaid.nih.gov> ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Sent: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" <@b iode fensecomm ission .org > Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From:Asha M. George <@biodefe nsecomm issio n.o rg> Sent : Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject : Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Sent: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George <@b iodefen secomm ission.o rg> Subject : Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" <@bio defe nsecomm ission .o rg > Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Sent : Tuesday, January 28, 2020 5:53 PM (b)(6) To : Asha M . George <@b iode fensecomm issio n.o rg> Subject : Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " <@b iode fensecomm issio n.o rg> Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Sent : Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject : Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Sent: Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Se nt: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject : Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Se nt: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov <@hhs.gov > Subject : Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From : andrew igla (b)(6)> Sent : Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov <@hhs .gov > Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From : andrew igla (b)(6)> Sent : Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov <@HHS.gov> Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From:andrew igla Sent: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Sent: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Sent: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Sent: To: Subject: Attachments : FYI From:Jeremy Farrar (b)(6)> Sent: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From:Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To : Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Sent: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Sent : To : Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Sent: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc:Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Se nt: Saturday, February 1, 2020 10:44 AM Subject : POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From : Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Sent : Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject : FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Sent: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To : Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus update: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To : Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subj ect : At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To : Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject : FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From : Sent : We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From : SWAMI NATHAN, Soumya ---------- Se nt: Saturday, February 1, 2020 7:19 AM To : Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject : 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To : 00~ Subject : FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Sent : Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject : 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Sent : Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject : Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From : Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Se nt : Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From:Folkers, Greg (NIH/NIAID) [E] (b)(6) Sent: Friday, January 31, 2020 8:43 PM Subject : Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles <@vitalant.org> Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global <@gl oba ldownsynd rome.org> Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk <@globaldownsyndrome .org>; Marisa Cucuzzella <@ajsfoundation .com>; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.<@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen <@cepi.net> Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park <@time.com> Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@turne r.co m> Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@t urner .com > Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc <@nyulangone.org> Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser <@patientsafetymovement .org> Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay <@patientsafetymovemen t .org> Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC <@who.int>, "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) <@resolvetosavelives.org>, , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey <@jesuits .org> Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com <@omcasa .com> Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) <@sky.uk> Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" <@wsj .com > Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi <@wsj.com> Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan <@cbsnews.com > ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay <@pitt.edu >wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay <@pitt.edu>wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick <@statnews .com> Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen <@brt.org> Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari <@scripps.edu> Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST<@utsouthwestern .edu>; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone <@scripps.edu>; Eckard Wimmer <@stonybrook.edu> Cc: Charles Rice <@scripps.edu> Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily <@americanchemistry .com> Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai <@npr.org> Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai <@npr .org> Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai <@npr .org> Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John (NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) <@knowledgeu .com> Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. <@fhn.org> Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg <@americanprogress.org> Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus <@americanprogress.org > Date: Thursday, August 15, 2019 11:21 AM To: Posted Products <@ame ricanp rogress.org> Cc: Kyle Epstein <@ame ricanprogress.org>; Daniella NIH-001111 Leger <@americanprogress.org > Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik <@npr.org > Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . <@abc .com> Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi <@thehill .com> Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi <@t hehi ll.com > Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen <@brook ings.edu> Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim <@brookings.edu> Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich <@ifaratv.org > Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu <@protherimmune.com> Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang <@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman <@ohsu .edu> Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" <@cdc.gov> , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan <@theatlantic.com> Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander <@rttv.ru> Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon <@keystonesymposia.org> Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon <@keystonesymposia.org> Cc: Heidi Daetwyler <@keystonesymposia .org> Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo <@isciii .es> Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo <@isciii.es> Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady <@economicclub.org> Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza <@economicclub.org> Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments <@hms.harvard.edu> Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara <@hms .harvard .edu>; Tekleab, Sarah <@hms.harvard .edu> Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai <@npr .org> Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra <@abc.com> Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park <@time.com> Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park <@t ime.com> wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas (NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David <@aaaai.org>; Rebecca Brandt (AAAAI) <@aaaai.org> Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie <@nas.edu> Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en <@aaas.org> Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" <@spglobal.com> Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" <@niaid.nih.gov>, "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna <@spglobal. com> Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" <@spglo bal.com > Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" <@niaid .nih .gov>, "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna <@spg loba l.com > Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" <@spg loba l.com > Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih .gov>; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia <@imf.org> On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita <@imf.org>; Milesi -Ferretti, Gian Maria ; Celasun, Oya <@imf .org>; Christiansen, Lone Engbo <@imf.org> Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC <@who .int>; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) <@m snbc.com > Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) <@msn bc.com > > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren <@turner .com> Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James <@wsj.com> Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" <@hhs.gov> Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/IO)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/OD)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/IO)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/IO)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/IO)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/IO)(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/IO) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/IO) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/IO) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/IO) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " <@nia id.nih.gov > Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" <@wtop .com > Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" <@wtop.com > Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" <@wtop.com > Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura <@wtop.com> Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett <@nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth <@nejm .org> Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth <@nejm.org> ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth <@nejm .org > Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org > Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth <@nejm.org > Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams <@nationalpress.org> Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth <@nejm.org> Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth <@ne jm .org> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org > Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti <@bbc.co .uk> Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams <@sibf.org> Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) <@nbcuni.com> Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth <@nejm.org> Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org> NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org> Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ <@thepaper.cn> Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" <@turner .com > Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G <@nytimes.com>w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton <@theasiagroup.com> Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" <@msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) <@tum er.com >wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" <@turner.com> Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) <@turner .com> Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike <@wtop.com> Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" <@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" <@siriusxm.com> Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks <@resolvetosavelives.org> __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC<@who .int>; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" <@b loomberg .net> Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" <@nia id.nih.gov> Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" <@bloomberg.net> Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley <@bdo.com> Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota <@bdo.com> Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen <@hsph.harvard .edu> Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@b loombe rg.net> Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloom berg .net> Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloo mberg .net > Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] <@nih.gov> Cc: Routh, Jennifer (NIH/NIAID) [E] <@nih .gov > Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloombe rg.net> Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net> Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) <@b loo m berg . net > Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloomb erg . n e t > NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI <@nytimes.com> Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine <@ma nuscriptcentral. com> Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne (NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net > Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) <@b loomberg.net> Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/IO) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" <@hhs.gov>, "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/IO) (b)( >; Stecker, Judy (OS/IOS) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/IO) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/IOS) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/IO)" <@hhs.gov >, "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/IOS) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/IO) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/IOS) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/IO) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/IO) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate (NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih .gov > Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] <@mail.nih.gov >; Collins, Francis (NIH/OD) [E] <@nih .gov>; Gilman, James (NIH/CC/OD) [El <@n ih.gov > Cc: Burklow, John (NIH/OD) [E) <@od .nih .gov >; Hallett , Adrienne (NIH/OD) [E) <@nih.gov >; Billet, Courtney (NIH/NIAID) [E) <@nia id .nih .gov>; Davey, Richard {NIH/NIAID) [E] <@cc.nih.gov >; Cohen, Justin {NIH/CC/OD) [El <@nih .gov > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz <@vox.com> Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz <@vox.com > wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis (NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG <@niaid.nih.gov > Cc: NIAID COGCORE<@niai d.nih .gov> Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci <@businesscouncil.com> Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen <@iasusa .org> Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen <@iasusa .org>; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen <@iasusa .org >; Barie, Toni C _________ _ <@iasusa.org >; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane <@:.. ____ (b) (b)(6) (b _ )_(_. 6>;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" <@t..,_____ Cb _)_@ ... wrote: Dear Ken, The (b) (6) . Committee greatly appreciatesyour willingnessto approach Dr. Anthony Fauci on our behalf, asking him to address the residents of the----,---, (b) (6) on the Coronavirus. It would perhaps be hel ful to Dr.Fauci, to ex lain who we are and what we do. (b) ( , (b)(6) The (b) ( Committee was ormed recently to create and orgamze events to e ucate, enlighten and entertain members of the Somerset community.A few weeks ago (b)(6) spoke to a sold out crowd on impeachment. We've featured authors on a variety of topics; invited doctors with specialtiesof interest to our communityorganized trips to the KennedyCenter and theaters for attendanceat ballets and plays and sponsored visits, led by experts, to various museums and the Library of Congress to view special exhibitions. An example of the latter is a tour of the Folger Library (b) (6). A presentationby Dr. Fauci on the coronaviruswould be of great interest to our constituencywho keep informed by reading both national and internationaljournals. We are flexible on the date for such an appearanceneeding only a few days' notice to inform our residents. I need not tell you that it wou ld our great honor to welcome Dr. Fauci to the NIH-001660 (b) (6):. Sincerely (b)(6) NIH-00166 1 From: Date: To: Cc: Subject: Eastern Daylight Time I totally agree. Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 12:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E) Marston, Hilary (NIH/NIAID) [E);Barasch, Kimber ly (NIH/NIAID) [CJ RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM I do not want to be on a "session planning" call. Please have Hilary do this as suggested by Patty since she is preparing t he talk . T hanks. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 21, 2020 4:44 PM To: Folkers, Greg (NIH/NIAID) [E] (b)( 6) ---------------~~ --------- (b)(6) (b)(6Jr>;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) <@MSNBC.COM> Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) <@nbcuni.com>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) <@MSNBC.CO M > Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM >; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@M SNBC.COM > Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) <@nbcuni.com > Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" <@MSNBC.COM> Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" <@nbcun i.com>, "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@n bcuni.com> Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie <@iasusa .org> Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen <@iasusa .org> Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen <@iasusa.org> Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie <@iasusa.org> Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen <@iasusa.org> Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G <@nytimes.com> Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G <@nyt imes.com> wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang <@caixin.com> Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost.com> Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel <@washpost.com> Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost Date: Thu rsday, February 20, 2020 5:51 PM .com > NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } <@niaid.nih.gov> Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller <@we ta.org> Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman <@biocentury .com> Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary <@USChamber.com> Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM <@niaid .nih.gov > Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao <@wor ldbank.org > Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla <@worldbank .org>; Rocio Schmunis <@worldbank .o rg>; Gabrielle Lynn Williams <@worldban k.org>; Muhammad Ali Pate <@worldba nk.org> Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall <@scgcorp.com> Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM <@n iaid. n i h.gov>; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria <@scgcorp.com>; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa <@scgcorp.com>; Megan Schartner <@scgcorp .com> Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention <@crit icalment ion .com> Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty <@manu scriptcentral.com > Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/OD);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM <@niaid.nih .gov> Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen <@iasusa.org > Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ <@iasusa.org > Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon <@aacr.org> Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine <@manuscriptcentral.com> Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <@o d. ni h.gov> Cc: NIAID COGCORE<@niaid .nih .gov> Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg <@mail.nih .gov> Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) <@nbcuni.com> Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com> ; Varela, Jay (NBCUniversal) <@nbcuni.com>; Mitchell, Alexander (NBCUniversal) <@nbcuni.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com> ; Metsch, Abigail (NBCUniversal) <@nbcuni.com> Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) <@nbcuni.com > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal) <@nbcun i.com>; Mitchell, Alexander (NBCUniversal) <@nbcun i.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcuni.com > Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) <@nbcuni.com > Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal ) <@nbcu ni .com>; Mitchell , Alexander {NBCUniversal) <@nbcuni.com >; DiCasimir ro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcun i.com > Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) <@turner .com> Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel <@turner .com>; Avramova, Nina (NE) <@turner.com> Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" <@t urn er .co m> Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" <@turne r.com >, Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike <@t urn er .co m> Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 <@t urner .com> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike <@tu rn er.co m> Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike <@tu rn er .com > wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty <@manuscriptcentral.com> Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. Additional information about disclosure of financial and other associations appears below this letter. Please bear in mind that your editoria l represents your (and any coautho r's) personal opinion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal po licy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manuscript can be accepted. Therefore, the enclosed form should be signed by all authors and faxed to (781) 207 -6529. Your editorial is due at the Journa l on Monday, February 17, at the very latest if the deadline imposed by our printing schedule is to be met. ff the editorial is to include a figure, please submit the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances <@l\1AFGRP.COM> Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h <@MAFGRP.COM > Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate <@umassmed.edu> Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish <@utoronto.ca> Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com <@happeningsmag.com > Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedviginc.com> Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko <@hedvigin c.com> wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedv iginc.com> Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles <@newshour .org> Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven <@....__ 1 Cb _>< ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" <@turner.com > Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike <@turne r.com > Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike <@turne r.com > Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike <@turner .com > wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike <@tu rner .com> wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike <@turner .com > Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike <@turner .com > Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike <@turne r.com > Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike <@turne r.com> Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike <@turne r.com > Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike <@turner .com> Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" <@tumer.com > Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B <@providence.org> Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 <@tovima.gr> Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) <@niaid.nih.gov > Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com <@leslevcahillroy.com> Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com <@lesleycahillroy.com> Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com <@lesleycahillroy.com> Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy <@lesle y cah ill roy .com > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com <@lesleycahil lroy .com > wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov <@egoist .bg> Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) <@niaid.nih.gov> Cc: NIAID Ocpostoffice (NIH/NIAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu <@umbc.edu > Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com <@lesleycahillroy.com> Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com <@lesleycahillroy .com> wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El <@niaid .nih .gov>; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg <@mail.nih.gov >; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg <@mail.nih .gov >; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg <@mail.nih.gov>; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg <@mail.nih.gov>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<@ethnos.gr> Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. <@nas.edu>; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma <@nas .edu>; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny <@nas .edu> (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau <@nas.edu> , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " <@nas.edu> , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " <@cnn.com>, "Amanda.Se aly@c nn.com " <@cnn.com >, "Neel.Kbairzada(a),turner.com " <@turner.com> , Cb)(6) "McGinnis, J.Mic hael" <@nas.edu> , CbH6) >, ''Mun , Jenny" <@nas.edu >, CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. <@nas.edu>; George (b)(6) ____ ; Hannon, Emma <@nas.edu>; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael<@nas.edu>; (b)(6)>; Mun, Jenny <@nas.edu > (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau <@nas.edu >, George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " <@cnn .com> , "Amanda.Sealy@cnn .com " <@turner.com " <@tumer.com> , (b)(6)"McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenny" <@nas.edu >, (b)(6) Emma" <@nas.edu >, "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. <@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma <@nas.edu>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. <@nas.edu> '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny <@nas.edu >, ------~~ (b)(6) ; 'ben.tinker@cnn .com ' <@cnn.com >; 'Amanda.Sealy@cnn .com' <@cnn.com >; 'Neel . Khairzada@turner.com' <@tumer.com >; (b)(6) 'Tia.Mi ller@turner.com' <@turner.com >; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson <@beatthebomb Date: Thursday, April 30, 2020 11:26 AM To: Fauci, Anthony (NIH/NIAID) [E) .com> (b)(6)> Cc: Daniel Lahart <@r egis.org> Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson <@beatthebomb .com> Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] <@niaid .nih.gov > Cc: Daniel Lahart <@regis.org> Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff <@svt.se> Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) <@niaid.nih.gov>; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM <@niaid .nih.gov> Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen <@brt .org > Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] <@niaid.nih.gov> Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] <@niaid.nih.gov> Cc: Folkers, Greg (NIH/NIAID) [El <@niaid.nih .gov>; Conrad, Patricia (NIH/NIAID) [El <@nih.gov>; Routh, Jennifer (NIH/NIAID) [El <@nih .gov>; Lane, Cliff (NIH/NIAID) [El <@nih.gov> Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedi a.co m> Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias <@ikanamedia.com > Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg <@mail.nih.gov>, " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM <@niaid.nih.gov > this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM <@niaid.nih.gov > Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti <@noiaft.org> Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG <@niaid .nih.gov> Cc: NIAID COGCORE<@mail.nih.gov>, NIAID Media Inquir ies <@niaid.nih.gov> Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang <@sinobio logical.info> Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia <@la7.it> Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM <@niaid .ni h.gov> (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda <@paypal.com > Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay <@edelman.com > Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de > Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf <@syntacoll.de> Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf <@syntacoll.de> -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.<@nas.edu>; George (b)(6) ; Hannon, Emma <@nas.edu>; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael <@nas.edu>; (b)(6) Mun, Jenny <@nas.edu>; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau <@nas.edu >, Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" <@nas.edu> , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" <@cnn.com>, ------------- (b) (6) "Amanda. Sealy@cnn .com " <@turne r.com " <@turner.com >, (b)(6) "McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenn y" <@nas.edu>, CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.<@nas.edu>; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma <@nas.edu>; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael<@nas.edu>; (b)(6)> ; Mun, Jenny <@nas.edu>; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau <@nas.edu >, George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" <@nas.edu >, "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " <@cnn.com >, "Amanda.Sealy@cnn.com " <@turner.com " <@turner.com > , (b)( 6) "McGinni s, J.Mi chael" <@nas.edu >, ---------------- CbH6) >, "Mun, Jenny" <@nas.edu>, (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.<@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a <@nas.edu >; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. <@nas.edu> Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.<@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' <@cnn.com >; ---------'Amanda.Sealy@cnn.com ' <@cnn.com >; 'Neel. Khairzada@turner .com' <@turner.com >; 'Tia.Miller@turner .com' <@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie <@ncdps.gov> Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD (CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie <@fda.hhs.gov> Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John (NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/IO) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/IO) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/IO) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan (OS/ASPR/IO) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/IO) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/IO) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/IO) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/IO) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) <@mail.nih.gov> Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/IO) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence (NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John (NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo <@lastampa.it> Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat <@hivr4p.org> Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier <@ourpubl icservice.org> Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies <@ourpublicserv ice.org> Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. <@nas.edu> Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma <@nas .edu>; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' <@cnn .com>; 'Amanda.Sealy@cnn.com' <@t urner .com' <@turner .com> ; (b) ( >; McGinni s, J. Mic hael <@nas.edu>; (b)( (b)(6) ; Mu n, Jenny <@nas .edu>; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma <@nas.edu>; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' <@cnn.com' <@t urne r.com>; 'Tia.M iller@turner .com' <@turner.com >; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith <@one .org> Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart <@one.org> Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements <@niaid .nih.gov> Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman<@sanaria.com> Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden <@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C <@who .int> , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC <@who.int> , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC <@who.int>; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC<@who .int>; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i <@fortaleza.pr.gov> Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan <@prfaa.pr .gov>; Juan L. Negron <@fortaleza.pr.gov>; Antonio L. Pabon Batlle <@forta leza.pr.gov> Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park <@time.com> Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov>;Conrad, Patricia {NIH/NIAID) [El <@niaid.nih.gov> Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams <@caa.com> Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman <@caa.com> ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams <@caa.com> Cc: Christine Lancman <@caa.com>, (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams <@caa.com> Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman <@caa.com > Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recip ient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexual harassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl <@fnih.org> Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. <@nas.edu> Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan <@nas.edu> Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha <@calhacks.io> Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams <@caa.com> Cc: Christine Lancman <@caa.com >; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams <@caa.com> Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman <@caa .com> Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines <@nih.gov > Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali <@turner.com > Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines <@nih.gov > Cc: Cohen, Elizabeth <@turner.com >; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim <@global -infra.com> Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen <@rockfound .org> Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] <@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield <@uw.edu > Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld <@uw.edu > Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield <@uw.edu> Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis (NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz <@w ashingtontimes.com > wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.<@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny <@nas.edu > Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. <@duke.edu> Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General <@who.int> , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s <@resolvetosave lives.org>, "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC <@who.int>, "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine <@manuscriptcentral.com > Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" <@niaid.nih.gov > Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " <@nejm.org > Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de> Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf <@syntacoll.de> Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf <@syntacoll.de> Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf <@syntacoll.de > Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf <@syntacoll.de> Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM <@n iaid.nih .gov> Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton <@keystonesymposia.org> Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith <@one.org> Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart <@one.o rg> Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy <@bclplaw .com> Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith <@one.org> Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart <@one .org> Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe <@washpost.com> Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE<@mail.nih.gov> Cc: NIAID OD AM <@niaid.nih.gov> Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton <@keyston esymposia .org> Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) <@service.gov deli very.com > Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. 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NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. (CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/IO) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/IO) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM <@ni aid .nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM <@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] <@niaid.nih.gov> Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]<@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [E] <@nih .gov>; Routh, Jennifer (NIH/NIAID) [E] <@nih.gov > Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/IOS) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie (NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton <@cpa -qc.ca> Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/IO) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner <@jamanetwork.org > Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa <@jamanetwork.org > Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner <@jamanetwork.org> Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r <@jaman etwork.org> Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM <@niaid.nih.gov> Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park <@ti me .com > Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews <@time.com > Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park <@time.com>w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana <@bizsecure .us> Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence (NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff <@whmo.mil> Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon <@mail.huji.ac.il> Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon <@mail.huji .ac.il> Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon <@mail.huji.ac.il> Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik <@neximmune .com> Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L <@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano <@asmusa.org> Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara (NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L<@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " <@list.nih.gov > Cc: List DEPDIR-L <@list.nih.gov >, NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole <@lewis -burke .com> Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby <@lewis-burke.com > Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" <@nbcuni.com> , Jeremy Schu lman <@schulmanbh.com > Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller <@schulmanbh.com> Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) <@knowledgeu.com> Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) <@knowledgeu.com>; Katie Dinsmore (kdinsmore@knowledgeu.com) <@knowledgeu.com> Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred <@washpost .com> Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter (NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC) [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. Next steps and way forward -- Do not delete or change any of the following text. -- Join Webex meeting Meeting number (access code): ---- (b)(4) Meeting password: ------- (b) (4) Join from a video system or application Dial ------,, You can also d ial (b) (4) (b)( 4) and ----- enter you r meeting numb er. Join by phone Tap to call in from a mobile device (attendees only) 1-650-479-3208 C all-in to ll number (US/Ca nada ) Global call-in numbers Join using Microsoft Lyne or Microsoft Skype fo r Business Dial ------------- Can't jo in the meeting ? (b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@goog le.com > Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park <@immunemed .co.kr> Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. <@nas.edu> Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny <@nas .edu>; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma <@nas .edu>; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' <@cnn.com' <@t urner.com>; 'Tia.M iller@turner.com' <@turner.com>; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny <@nas.edu> Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' <@cnn.com>; 'Nee l.Khairzada@turner.com' <@turner.com' <@turner.com> Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney <@topspinconten t.com> wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn <@ap.org Date: Sunday, April 12, 2020 10 :56 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= > CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT<@state .co.us> Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias <@ikan amed ia.com>wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM <@niaid.nih.gov> Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon <@jsg.utex as.edu> Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall <@editoria lmanag er.com> Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley <@theatlantic.com> Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley <@theatlantic.com> Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX <@radio-canada.ca> Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" <@niaid .nih.gov>, "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE<@ma il.nih .gov>; NIAID OD AM <@niaid.nih.gov> Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante <@outlook.it> Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih.gov> Cc: Barasch,Kimberly (NIH/NIAID) [C) <@nih.gov>;Conrad, Patricia {NIH/NIAID) [E) <@niaid.nih.gov> Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC <@who.int> , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) <@resolvetosavelives.org > , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC <@w ho.int> , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) <@nia id .nih .gov> Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements <@niaid.nih.gov> Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line <@ors.od.nih.gov > Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@google.com> Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB <@mail.nih .gov> Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe <@joffeemergencyservices.com> Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: <@pnascentral.org> Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate (NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/IOS) CbH6)Shuy, Bryan (OS/ASPR/IO) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis (NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/IO) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NIH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/IO) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/IO) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/IO) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/IO) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/IO) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/IO) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/IO) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/IO) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/IO) CbH6)>;Callahan, Victoria (OS/ASPR/IO) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6)>;Windom, Robert (OS/ASPR/IO) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/IO); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/IO); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/IO); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/IO); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/OD); Windom , Robert (OS/ASPR/IO) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/IOS) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/IOS) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/IOS) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/IOS) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert <@pennme d icine.upenn.edu > Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando <@ma rianneorlando .com> Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs <@usc.edu> Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' <@nic.in >; Toomas (b)(6)>; GPMB Secretariat <@who.int >; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' <@nic.in >; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' <@nic.in >; Toomas Palu GPMB Secretariat <@who.int >; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak <@live.ca> Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s <@thetrek.co > Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam (NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani <@blood.ac. tz> Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" <@w ashpost.co m> Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar <@bobbleheadhall.com> Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary <@washpost.com> Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L <@list. nih.gov> Cc: NIH Director's Executive Committee <@mail.n ih.gov> Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " <@list.nih.gov > Cc: NIH Directo r's Executive Committee <@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 <@globalreporter.it > Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti <@milfo rd.nh.gov> Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G <@nytimes.com>wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar <@bobbleheadhall.com> Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: <@ny times.com> Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin <@arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." <@abgenics.in> Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich <@biosan itize.us> Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor <@b iosan itize.us" <@biosani tize.us> Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo <@optimumre .com> Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" <@the-times.co.uk > Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" <@mail.huji. ac.il> Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona <@canyonranch.com> Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker <@therimunex.com> Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona <@canyonranch.com > Cc: Patricia Maxwell <@canyonranc h.com >, "dgrange @osp reyg lobalsol utions.com" <@ospreyg lobalso luti ons .com > Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " <@myseneca .ca> Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie <@empowerme.e nterprises> Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden <@blindfish .media> Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue <@demiurge. technology >wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue <@demiurge.technology > Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco <@cn io.es> Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. De conformidad con lo dispuesto en el Reglamento (UE) 2016/679 relativo a la protecci6n de los datos personales de las personas ffsicas, la informaci6n personal que nos pueda facilitar a traves de este correo electr6nico quedara registrada por la Fundaci6n CNIO con la finalidad de tramitar el objeto del presente correo electr6nico . El tratamiento de sus datos personales se encuentra legitimado por ser necesario para gestionar el objeto del presente mensaje. Estos datos personales no seran comunicados a ningun destinatario salvo a aquellos que usted nos auto rice o asf venga exigido por una ley. Ud. podra NIH-000151 ejercer los derechos de acceso, rectificac i6n , supresi6n, limitaci6n de tratamiento , portabil idad y oposici6n en la siguiente direcci6n : c/Melchor Fernandez Almagro 3, 28029 (Madrid). Podra ponerse en contacto con el Delegado de Protecci6n de Datos en: delegado lopd@cnio.es. Para el caso de que Ud. precise conocer informaci6n adicional sobre el tratamiento de sus datos personales, puede consultar dicha informaci6n adicional en el siguiente enlace dentro de nuestra pagina web: https://www.cnio.es/es/privacidad/index .asp **LEGAL NOTICE**: This email and any attached files may contain protected information for the sole use of its intended recipient or addressee. Anyone other than the intended recipient or addressee is strictly prohibited from distributing , reproducing or transmitting the email and its contents in any way. If you receive this email in error, please notify the sender and delete the message. Pursuant to the provisions of EU Regulation 2016/679 regarding the protection of personal data, any personal information you provide through this emai l will be registered by the CNIO Foundation in order to deal with content of this email. Your personal data must be processed in order to be able to deal with the content and purpose of this message. Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L<@mail.nih.gov>; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM <@niaid .nih .gov>; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it <@libero.it> Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamedia.com> Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback <@ncbi.nlm. nih.gov> Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias <@ikanamedia .com> Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe <@frame.media > Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe <@frame.media >wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA)<@cell.com> Cc: Fauci, Anthony (NIH/N IAID) [E] <@niaid.nih.gov> Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) <@cell.com > Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA)<@cell.com > Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William <@apcoworldwide .com > Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore <@health.ucsd.edu> Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n <@health Subject: Re: George Church interview Date: March 24, 2020 at 12:09:20 PM PDT To: Jon Cohen <@aaas.org> NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen <@aaas.org> wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore <@ucsd.edu> wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC<@who .int> ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives <@reso lvetosavelives .org>; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC<@who.int>; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand <@rttv .fr> Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg <@n iaid .nih .gov>; NIAID COGCORE<@mail.nih.gov> Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC <@everb ri dge.net > Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen <@washpost.com > Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley <@washpost.com > Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams <@wamu.org > Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" <@niaid.nih .gov> Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " <@LIST.NIH .GOV> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson <@fannocreek .com> Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner <@jamanetwork.org> Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani <@jamanetwork .org> Cc: Edward Livingston <@jamanetwork .org> Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner <@jamanetwo rk.org>, Tony Fauci 6b , Preeti Malan i <@med.um ich.edu>, Eli Perencevich , Phil Fontanarosa <@jamanetwork.o rg> Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner <@jamanetwo rk.org> Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD) [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G <@nytimes.com> Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan <@georgetown.edu> Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) <@uidaho .edu> wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re <@health.ucsd .edu> wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" <@sriramachandra .edu.in> Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna <@ho lycross .bc.ca>wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D <@email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly <@aaas.org> Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard <@rwjf .org> Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis (NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila <@nyt imes .com > Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila <@nytimes .com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes .com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila <@nytimes.com> Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila <@nytim es.com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes.com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen <@b io- signal.com> Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila <@nyt imes.com> Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila <@nyt imes.com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John (NIH/OD) [E] (b)(6) CbH >; Fine, Amanda (NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@ny t imes.com > wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis (NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis (NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis (NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming <@nature .com> Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey <@bio.org > Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = <@bio.org> --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias <@ikanamedia.com > Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias <@ikanamedia.com> Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason <@wsj.com> Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE<@n iaid.nih.gov>; NIAID FOG<@niaid .nih .gov> Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/IO) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<@,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" <@FOXNEWS.COM> Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret <@FOXNEWS.COM> Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley <@FOXNEWS.COM>; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret <@FOXNEWS.COM> Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley <@FOXNEWS.COM> Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley <@FOXNEWS.COM> Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley <@foxnews.com >wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 <@foxne ws.com >wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis (NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar <@tytocare .com> Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson <@zrgpartners.com> Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson <@robinsonmanagementserv ice.com > wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y <@howard.edu> wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones <@winning-newsmedia.com> wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" <@turne r.com > Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian <@slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian <@slammiami.com> -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq <@jsgroup.com.kw> wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson <@med.cornell.edu>wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 <@columbi a.edu>; kathleen foley (b)(6); Carol Storey-Johnson <@med .corn ell .edu > Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/IOS);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/IOS);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy (OS/IOS) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/IO) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/IO) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/IO)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling <@literacymatters .education> Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley <@researchamerica .org > Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney <@resea rchamerica .org> Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah <@cbsnews.com> Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] <@cbsnews.com> Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah <@cbsnews .com> Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam <@cbsnews .com > Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu <@stanford.edu> Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" <@stanford.edu >, Amanda Chase <@sta nford.edu > Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe <@hms.harvard.edu> Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas<@bernstein.com > Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas <@be rnste in.com > Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas <@economist.com> Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas <@econ omist.com >wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly <@theceoforumgroup .com> Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller <@cbc .ca> Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke <@americamedia.org > Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 <@wolf lawyer.com> Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NIH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray <@mrc .ac.za> Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin <@hdltherapeutics.com> Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert <@steinmancommunications.com> Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur <@bio.or g> Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur <@bio .org> Cc: Jenni fe r Alton <@pathwaypolicy .com>, Ellen Carlin (bH6) >, Amy Walker <@bio.org>, Grego1yFrank ---------<@bio.org> Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone <@scripps.edu> Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada <@elconfidencial.com> Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah <@bmc .org> Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" <@scientekpower.com> To: (b)(6) Reply-To: <@scientekpower .com> Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm <@kammconsultinginc.com> Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) <@msnbc .com> Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison <@csis .org> Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman <@csis.org> Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison <@cs is.org > wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra <@abc.com> Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra <@a bc.com > > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/IO) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/IO)" (b)(6) "Hamel , Joseph (OS/ASPR/IO)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/IO)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/IO) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/IO) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (OS/ASPR/IO) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/IO) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/IO); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/IO) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/IO); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/IO) (b)( >; Hamel, Joseph (OS/ASPR/IO) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/IO)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/IO) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/IO) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/IO): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t (OS/ASPR/IO) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/IO) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/IO): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/IO): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/IO): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/IO): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/IO) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/IO) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/IO) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/IO) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/IO)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan (OS/ASPR/IO)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan (OS/ASPR/IO) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) (OS/IOS)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/IO) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/IO) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/IO)" (b)(6), "Yeskey, Kevin (OS/ASPR/IO)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/IO)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/IO) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/IO) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/IO) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/IO) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List <@LISTSERV .CDC.GOV> On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen <@was hpost .com> Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F.<@Kennedy-Center .org> Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary <@Kennedy-Center .org> Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul <@thaiembdc.org> Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya <@thaiembdc .org> Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara (NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <@vox.com>wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM <@niaid.nih .gov> Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling <@thedocumentarygroup .com> Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/OD);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas <@airlines.org> Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg <@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) <@bloomb erg .net>wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) <@bloomberg .net> Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci <@businesscouncil.com> Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball <@businesscoun cil.com >; Gillian Auger <@bus inesscounc il.com > Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci <@businesscouncil.com> wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci <@businesscouncil.com > Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg <@eng.us> Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov> Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg <@ama -assn.org> Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM <@niaid.nih .gov> Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM <@niaid.nih .gov> Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison <@csis.org> Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll <@csis.org>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman <@pl et te r .com> Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ <@stimes.cn> Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal <@mai lonline .com> Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero <@pazienti.it> Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza <@pazienti.it> Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" <@wtop .com > Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses <@usasiainstitute .org> Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine <@trilateral.org> Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig <@tr ilateral.org> Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M.<@abc.com> Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan <@cbsnews.com > ; Jay Shaylor <@cbsnews.com > Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim <@cnn .com > Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) <@zeemedia.esselgroup.com> Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) <@zeemedia.esselgroup (W 10 .com> Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) <@zeemed ia.esselgroup.com >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) <@zeemed ia.esselgroup .com > Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <@zeemed ia.esselgro up.com> Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) <@zeemed ia.esselgrou p.com >; KUMAR SUNNY <@zeemedia.esselgroup.com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) <@zeemed ia.esselgroup.com > Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) <@zeemed ia.esselgrou p.com > Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemed ia.esselgroup. com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) <@zeemedia.esselgroup.com> Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) <@zeemedia.esselgroup.com> Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgroup .co m> Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) <@zeemedia .esselgr oup.com > wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgro up .com > Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) <@zeemed ia.esselgroup.com > Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations<@zeemedia.esselgroup.com> Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" <@turner.com > Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " <@turner .com> Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle <@turne r.com> Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle <@turner .com > wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle <@turner.com > Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle <@tu rner .com> wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle <@tu rner .com> Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle <@turne r.com > Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo <@kff.org> Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" <@turner.com > Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie <@turner .com> Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) <@turner .com> Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) <@turner .com> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <@turner .com> wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner .com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) <@turner .com > wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) <@turner.com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner.com > wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) <@turner .com > Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@turner .com > Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" <@turner.c om >, "Lovejoy, Hannah NIH-00203 1 (NE)" <@turn er .com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve<@cowen .com> Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil <@cowen.com>; Nedelcovych, Michael <@cowen.com> Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" <@tumer.com >, "Lovejoy , Hannah (NE)" <@tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) <@turner.com> Cc: Pfeifer, Hazel <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) <@turne r.com>wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@t urner .com >; Lovejoy, Hannah (NE) <@turner .com >; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) <@turne r. com>wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner .com>; Lovejoy, Hannah (NE) <@turne r.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner .com >wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) <@turner .com > Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) <@turner.com> Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" <@turner.com > , "Lovejoy , Hannah (NE)" <@turner.com > Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias <@ikanamed ia.com> Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae <@wtop.com> Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae <@wtop.com > Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal <@wtop .com> wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" <@wtop .com> Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal <@wtop .com > Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM <@niaid .nih .gov> Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle <@turner.com> Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" <@FOXNEWS.COM> Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra <@FOXNEWS.COM> Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra <@foxnews.com > wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram <@medpagetoday.com> Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano <@buzzfeed .com> Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda <@gannett.com> Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner <@jamanetwork.org> Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor <@ama-assn .org > Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork.org >, Annette Flanagin <@jamanetwork.o rg>, Michae l Berkwits <@ama-assn.org >, Brian Shields <@ama -assn.o rg>, Sean O'Donnell NIH-002097 <@ama-assn.erg> Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner <@jamanetwork.org> Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r <@ama - assn.org> Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork .org >, Annette Flanag in <@jamanetwork.org >, Michae l Berkwits <@jamanetwork.org >, Tom Easley <@ama -assn.org >, Brian Shields <@ama -assn.org >, Sean O'Donnell <@ama-assn .org > Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/OD);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb <@gmai l.com> wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner <@jamanetwork .org> Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner <@jamanetwork.org> Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner <@jamanetwork.org> Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner <@jama netwo rk.org> Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner <@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner <@jamanetwork.org >; Phil Fontanarosa <@jamanetwork.org > Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth <@turner.com> Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons <@t hehill .com> Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq <@ntv.ru> Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee <@bbc.co.uk> Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" <@mail.nih.gov>, "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/IOS); Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD) [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/IOS) (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/IO) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) <@HHS.GOV> Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/IO) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/IO) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/IO) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil (NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis (NIH/OD) [El (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/IOS) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/IO) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10<@hhs .gov>; ASPRExec Sec (OS/ASPR)<@hhs .gov> Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas <@t heat lant ic.com > Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/IOS); Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD) [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/IOS) (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <@hhs .gov > Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" <@hhs.gov > Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral <@hhs.gov > Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral <@hhs.gov > Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. <@nejm.org>wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@ne j m.org> --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org > Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. <@nejm.org >wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@nejm.org> Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. <@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.o rg> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY <@ahaber .com .tr> _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil (NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile (NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis (NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ (NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci <@businesscouncil.com> Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein <@carly le.com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani <@ipsos.com> Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit <@v oanews.com > Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm.o rg> Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.<@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. <@nejm .org > Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller <@cbc.ca> Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. <@nejm .org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner <@jamanetwork.org> Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin <@jamanet w ork .org>; Christiansen, Stacy <@jama network .o rg>; Demetrios Kyriacou <@i amanetwo rk .o rg>; Edward Livingston CbH6>>; Fontanaros, Phil <@jama-archives.org >; GoIub, Robert <@jama-a rchives.org>; Gregory Curfman --------------- NIH-002241 <@jama-archives.org ; Jody Zylke <@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits <@jamanetwork .org>; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <@jamanetwork.o rg>; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub <@jamanetwo rk.org>; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ <@niaid.nih .gov> Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) <@n iaid .n i h,gov > Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamed ia.com > Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias <@ikanamedia .com> wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) <@zeemedia.esselgroup.com> Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations <@zeemedia.esselgroup.com> Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] <@niaid .nih .gov> Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth <@aspenin stitute.org> Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth <@aspenin stitute.org> Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth <@aspeninstitut e.org> -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth <@aspeninstitute.org > Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth <@aspenin stitute.org > Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth <@aspenin stitute.org > Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth <@aspeninst itute.org >> Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth <@aspen institu te.org >> Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org <@aspen insti tute.org > 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle <@th irteen.org> Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <@bloomberg .net > Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica <@ansa.it> Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca <@npr.org> Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM <@niaid.n ih.gov> Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED <@afp.com > Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) <@nbcuni.com> Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) <@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) <@n bcun i .com> wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) <@nbcuni. com > Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis (NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis (NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci <@businesscouncil.com> Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein <@carlyle .com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail <@gmail.com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ (NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." <@cbsnews.com> Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" <@n iaid.nih.gov> ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" <@b iode fensecomm ission .org > Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George <@biodefe nsecomm issio n.o rg> Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George <@b iodefen secomm ission.o rg> Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" <@bio defe nsecomm ission .o rg > Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George <@b iode fensecomm issio n.o rg> Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " <@b iode fensecomm issio n.o rg> Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov <@hhs.gov > Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov <@hhs .gov > Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov <@HHS.gov> Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis (NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles <@vitalant.org> Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global <@gl oba ldownsynd rome.org> Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk <@globaldownsyndrome .org>; Marisa Cucuzzella <@ajsfoundation .com>; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.<@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen <@cepi.net> Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park <@time.com> Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@turne r.co m> Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@t urner .com > Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc <@nyulangone.org> Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser <@patientsafetymovement .org> Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay <@patientsafetymovemen t .org> Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC <@who.int>, "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) <@resolvetosavelives.org>, , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey <@jesuits .org> Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com <@omcasa .com> Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) <@sky.uk> Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" <@wsj .com > Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi <@wsj.com> Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan <@cbsnews.com > ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay <@pitt.edu >wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay <@pitt.edu>wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick <@statnews .com> Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen <@brt.org> Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari <@scripps.edu> Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST<@utsouthwestern .edu>; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone <@scripps.edu>; Eckard Wimmer <@stonybrook.edu> Cc: Charles Rice <@scripps.edu> Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily <@americanchemistry .com> Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai <@npr.org> Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai <@npr .org> Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai <@npr .org> Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John (NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) <@knowledgeu .com> Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. <@fhn.org> Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg <@americanprogress.org> Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus <@americanprogress.org > Date: Thursday, August 15, 2019 11:21 AM To: Posted Products <@ame ricanp rogress.org> Cc: Kyle Epstein <@ame ricanprogress.org>; Daniella NIH-001111 Leger <@americanprogress.org > Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik <@npr.org > Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . <@abc .com> Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi <@thehill .com> Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi <@t hehi ll.com > Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen <@brook ings.edu> Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim <@brookings.edu> Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich <@ifaratv.org > Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu <@protherimmune.com> Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang <@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman <@ohsu .edu> Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" <@cdc.gov> , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan <@theatlantic.com> Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander <@rttv.ru> Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon <@keystonesymposia.org> Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon <@keystonesymposia.org> Cc: Heidi Daetwyler <@keystonesymposia .org> Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo <@isciii .es> Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo <@isciii.es> Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady <@economicclub.org> Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza <@economicclub.org> Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments <@hms.harvard.edu> Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara <@hms .harvard .edu>; Tekleab, Sarah <@hms.harvard .edu> Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai <@npr .org> Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra <@abc.com> Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park <@time.com> Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park <@t ime.com> wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas (NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David <@aaaai.org>; Rebecca Brandt (AAAAI) <@aaaai.org> Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie <@nas.edu> Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en <@aaas.org> Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" <@spglobal.com> Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" <@niaid.nih.gov>, "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna <@spglobal. com> Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" <@spglo bal.com > Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" <@niaid .nih .gov>, "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna <@spg loba l.com > Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" <@spg loba l.com > Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih .gov>; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia <@imf.org> On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita <@imf.org>; Milesi -Ferretti, Gian Maria ; Celasun, Oya <@imf .org>; Christiansen, Lone Engbo <@imf.org> Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC <@who .int>; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) <@m snbc.com > Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) <@msn bc.com > > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren <@turner .com> Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James <@wsj.com> Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" <@hhs.gov> Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/IO)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/OD)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/IO)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/IO)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/IO)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/IO)(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/IO) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/IO) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/IO) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/IO) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " <@nia id.nih.gov > Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" <@wtop .com > Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" <@wtop.com > Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" <@wtop.com > Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura <@wtop.com> Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett <@nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth <@nejm .org> Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth <@nejm.org> ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth <@nejm .org > Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org > Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth <@nejm.org > Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams <@nationalpress.org> Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth <@nejm.org> Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth <@ne jm .org> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org > Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti <@bbc.co .uk> Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams <@sibf.org> Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) <@nbcuni.com> Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth <@nejm.org> Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org> NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org> Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ <@thepaper.cn> Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" <@turner .com > Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G <@nytimes.com>w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton <@theasiagroup.com> Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" <@msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) <@tum er.com >wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" <@turner.com> Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) <@turner .com> Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please NIH-001355 notify the sender by return e-mail and delete it from your system . You shou ld not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email includjng any attachment s may be privileged or confidential and is intended exclusively for the addressee . The views expressed may not be official policy , but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce , distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertaimnent Networks International Limited (Company No. 2803512), Turner Broadcas ting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House , 16 Great Marlborough Street, London Wl F ?HS. NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike <@wtop.com> Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" <@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" <@siriusxm.com> Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks <@resolvetosavelives.org> __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC<@who .int>; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" <@b loomberg .net> Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" <@nia id.nih.gov> Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" <@bloomberg.net> Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley <@bdo.com> Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota <@bdo.com> Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen <@hsph.harvard .edu> Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@b loombe rg.net> Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloom berg .net> Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloo mberg .net > Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] <@nih.gov> Cc: Routh, Jennifer (NIH/NIAID) [E] <@nih .gov > Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloombe rg.net> Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net> Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) <@b loo m berg . net > Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloomb erg . n e t > NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI <@nytimes.com> Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine <@ma nuscriptcentral. com> Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne (NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net > Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) <@b loomberg.net> Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/IO) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" <@hhs.gov>, "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/IO) (b)( >; Stecker, Judy (OS/IOS) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/IO) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/IOS) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/IO)" <@hhs.gov >, "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/IOS) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/IO) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/IOS) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/IO) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/IO) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate (NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih .gov > Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] <@mail.nih.gov >; Collins, Francis (NIH/OD) [E] <@nih .gov>; Gilman, James (NIH/CC/OD) [El <@n ih.gov > Cc: Burklow, John (NIH/OD) [E) <@od .nih .gov >; Hallett , Adrienne (NIH/OD) [E) <@nih.gov >; Billet, Courtney (NIH/NIAID) [E) <@nia id .nih .gov>; Davey, Richard {NIH/NIAID) [E] <@cc.nih.gov >; Cohen, Justin {NIH/CC/OD) [El <@nih .gov > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz <@vox.com> Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz <@vox.com > wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis (NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG <@niaid.nih.gov > Cc: NIAID COGCORE<@niai d.nih .gov> Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci <@businesscouncil.com> Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen <@iasusa .org> Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen <@iasusa .org>; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen <@iasusa .org >; Barie, Toni C _________ _ <@iasusa.org >; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane <@:.. ____ (b) (b)(6) (b _ )_(_. 6>;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" <@t..,_____ Cb _)_@ ... wrote: Dear Ken, The (b) (6) . Committee greatly appreciatesyour willingnessto approach Dr. Anthony Fauci on our behalf, asking him to address the residents of the----,---, (b) (6) on the Coronavirus. It would perhaps be hel ful to Dr.Fauci, to ex lain who we are and what we do. (b) ( , (b)(6) The (b) ( Committee was ormed recently to create and orgamze events to e ucate, enlighten and entertain members of the Somerset community.A few weeks ago (b)(6) spoke to a sold out crowd on impeachment. We've featured authors on a variety of topics; invited doctors with specialtiesof interest to our communityorganized trips to the KennedyCenter and theaters for attendanceat ballets and plays and sponsored visits, led by experts, to various museums and the Library of Congress to view special exhibitions. An example of the latter is a tour of the Folger Library (b) (6). A presentationby Dr. Fauci on the coronaviruswould be of great interest to our constituencywho keep informed by reading both national and internationaljournals. We are flexible on the date for such an appearanceneeding only a few days' notice to inform our residents. I need not tell you that it wou ld our great honor to welcome Dr. Fauci to the NIH-001660 (b) (6):. Sincerely (b)(6) NIH-00166 1 From: Date: To: Cc: Subject: Eastern Daylight Time I totally agree. Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 12:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E) Marston, Hilary (NIH/NIAID) [E);Barasch, Kimber ly (NIH/NIAID) [CJ RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM I do not want to be on a "session planning" call. Please have Hilary do this as suggested by Patty since she is preparing t he talk . T hanks. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 21, 2020 4:44 PM To: Folkers, Greg (NIH/NIAID) [E] (b)( 6) ---------------~~ --------- (b)(6) (b)(6Jr>;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) <@MSNBC.COM> Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) <@nbcuni.com>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) <@MSNBC.CO M > Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM >; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@M SNBC.COM > Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) <@nbcuni.com > Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" <@MSNBC.COM> Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" <@nbcun i.com>, "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@n bcuni.com> Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie <@iasusa .org> Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen <@iasusa .org> Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen <@iasusa.org> Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie <@iasusa.org> Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen <@iasusa.org> Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G <@nytimes.com> Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G <@nyt imes.com> wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang <@caixin.com> Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost.com> Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel <@washpost.com> Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost Date: Thu rsday, February 20, 2020 5:51 PM .com > NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } <@niaid.nih.gov> Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller <@we ta.org> Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman <@biocentury .com> Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary <@USChamber.com> Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM <@niaid .nih.gov > Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao <@wor ldbank.org > Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla <@worldbank .org>; Rocio Schmunis <@worldbank .o rg>; Gabrielle Lynn Williams <@worldban k.org>; Muhammad Ali Pate <@worldba nk.org> Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall <@scgcorp.com> Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM <@n iaid. n i h.gov>; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria <@scgcorp.com>; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa <@scgcorp.com>; Megan Schartner <@scgcorp .com> Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention <@crit icalment ion .com> Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty <@manu scriptcentral.com > Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. Please provide a title not exceeding 45 characters and a word count for the text; the entire manuscript, including references, should be double-spaced. REFERENCES Cite no more than 10 references, including the article you are writing about. The average collection of 10 references requires about a quarter of a printed page. TABLE OR FIGURE A table or a figure in your editorial will requ ire a reduction in the number of words; because figures and table s vary in size, you may be asked to shmten the text of your editorial during the production process. A quarter-page table roughly equals 250 words , and a half-page table roughly equals 500 words. DISCLOSURES When completing your disclosure form, please indicate, in the "Comments" field next to the type ofre lationship being disclosed , the amount (in U.S. dollars) of any support you have received. Please also indicate how much of this support has been received over the past 2 years. Please e-mail your completed disclosure form to editorial @nejm.org. NIH-001757 ln the event of publication, each author's submitted disclosure form will be posted on the Web (with any dollar amounts redacted). COPYR IGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 78 1-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIA L *** It is important that you follow the instructions below to ensure that you r article enters the correct queue. *** When you are ready to submi t your manuscript, please log in to the New England Journal of Medicine - Manuscript Centra l site Q1ttp:// mc05.manuscriptcen tral.com /nejm). Your case -sensitive USER ID is afauci @ niaid .nih.gov. For sec urity purposes, your password is not listed in this message. If you are unsure of your password , please visit hltps ://mc05.manuscr iptccntral.com /nejm and enter your e-ma il address in the "Forgot Your Password?" field. Once you are logged in, the Main Menu will be displayed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001758 Please wait. .. If this message is not eventually replaced by the proper contents of the document, your PDF viewer may not be able to display this type of docume nt. You can upgrade to the latest version of Adobe Reader for Windows®, M ac, or Linux ® by visiting http ://www.adob e.com/go/reader_downl oad. For more assistance with Adobe Reader visit http ://www .adobe.com/go/acrreader. Windows is eithe r a registered trademark or a trndemark of M icrosoft Corporation in the United States and/or other co untries. Mac is a trademark of Apple Inc ., registered in the United S1ates and other countries . Linux is !he registered trademar k of Linus Torvalds in the U.S . and other countries. NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/OD);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM <@niaid.nih .gov> Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen <@iasusa.org > Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ <@iasusa.org > Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon <@aacr.org> Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine <@manuscriptcentral.com> Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <@o d. ni h.gov> Cc: NIAID COGCORE<@niaid .nih .gov> Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg <@mail.nih .gov> Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) <@nbcuni.com> Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com> ; Varela, Jay (NBCUniversal) <@nbcuni.com>; Mitchell, Alexander (NBCUniversal) <@nbcuni.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com> ; Metsch, Abigail (NBCUniversal) <@nbcuni.com> Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) <@nbcuni.com > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal) <@nbcun i.com>; Mitchell, Alexander (NBCUniversal) <@nbcun i.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcuni.com > Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) <@nbcuni.com > Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal ) <@nbcu ni .com>; Mitchell , Alexander {NBCUniversal) <@nbcuni.com >; DiCasimir ro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcun i.com > Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) <@turner .com> Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel <@turner .com>; Avramova, Nina (NE) <@turner.com> Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" <@t urn er .co m> Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" <@turne r.com >, Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike <@t urn er .co m> Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 <@t urner .com> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike <@tu rn er.co m> Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike <@tu rn er .com > wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty <@manuscriptcentral.com> Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. Additional information about disclosure of financial and other associations appears below this letter. Please bear in mind that your editoria l represents your (and any coautho r's) personal opinion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal po licy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manuscript can be accepted. Therefore, the enclosed form should be signed by all authors and faxed to (781) 207 -6529. Your editorial is due at the Journa l on Monday, February 17, at the very latest if the deadline imposed by our printing schedule is to be met. ff the editorial is to include a figure, please submit the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. Please provide a title not exceeding 45 characters and a word count for the text; the entire manuscript , including references , should be double-spaced. REFERENCES Cite no more than 10 references , including the article you are writing about. The average collection of 10 references requires about a quarter of a printed page. TABLE OR FIGURE A table or a figure in your edito,ial will require a reduction in the number of words ; because figures and tables vary in size, you may be asked to shorten the text of your editorial during the production process. A quarter-page table roughly equals 250 words , and a half-page table roughly equals 500 words. DISCLOSURES When completing your disclosure fonn , please indicate, in the "Comments" field next to the type of relationship being disclosed, the amount (in U.S. dollars) of any support you have received. Please also indicate how much of NIH-001808 this support has been received over the past 2 years. Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances <@l\1AFGRP.COM> Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h <@MAFGRP.COM > Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate <@umassmed.edu> Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish <@utoronto.ca> Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com <@happeningsmag.com > Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedviginc.com> Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko <@hedvigin c.com> wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedv iginc.com> Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles <@newshour .org> Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven <@....__ 1 Cb _>< ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" <@turner.com > Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike <@turne r.com > Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike <@turne r.com > Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike <@turner .com > wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike <@tu rner .com> wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike <@turner .com > Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike <@turner .com > Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike <@turne r.com > Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike <@turne r.com> Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike <@turne r.com > Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike <@turner .com> Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" <@tumer.com > Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B <@providence.org> Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 <@tovima.gr> Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) <@niaid.nih.gov > Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com <@leslevcahillroy.com> Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com <@lesleycahillroy.com> Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com <@lesleycahillroy.com> Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy <@lesle y cah ill roy .com > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com <@lesleycahil lroy .com > wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov <@egoist .bg> Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) <@niaid.nih.gov> Cc: NIAID Ocpostoffice (NIH/NIAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu <@umbc.edu > Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com <@lesleycahillroy.com> Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com <@lesleycahillroy .com> wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El <@niaid .nih .gov>; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg <@mail.nih.gov >; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg <@mail.nih .gov >; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg <@mail.nih.gov>; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg <@mail.nih.gov>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<@ethnos.gr> Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. <@nas.edu>; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma <@nas .edu>; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny <@nas .edu> (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau <@nas.edu> , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " <@nas.edu> , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " <@cnn.com>, "Amanda.Se aly@c nn.com " <@cnn.com >, "Neel.Kbairzada(a),turner.com " <@turner.com> , Cb)(6) "McGinnis, J.Mic hael" <@nas.edu> , CbH6) >, ''Mun , Jenny" <@nas.edu >, CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. <@nas.edu>; George (b)(6) ____ ; Hannon, Emma <@nas.edu>; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael<@nas.edu>; (b)(6)>; Mun, Jenny <@nas.edu > (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau <@nas.edu >, George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " <@cnn .com> , "Amanda.Sealy@cnn .com " <@turner.com " <@tumer.com> , (b)(6)"McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenny" <@nas.edu >, (b)(6) Emma" <@nas.edu >, "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. <@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma <@nas.edu>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. <@nas.edu> '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny <@nas.edu >, ------~~ (b)(6) ; 'ben.tinker@cnn .com ' <@cnn.com >; 'Amanda.Sealy@cnn .com' <@cnn.com >; 'Neel . Khairzada@turner.com' <@tumer.com >; (b)(6) 'Tia.Mi ller@turner.com' <@turner.com >; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson <@beatthebomb Date: Thursday, April 30, 2020 11:26 AM To: Fauci, Anthony (NIH/NIAID) [E) .com> (b)(6)> Cc: Daniel Lahart <@r egis.org> Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson <@beatthebomb .com> Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] <@niaid .nih.gov > Cc: Daniel Lahart <@regis.org> Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff <@svt.se> Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) <@niaid.nih.gov>; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM <@niaid .nih.gov> Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen <@brt .org > Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] <@niaid.nih.gov> Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] <@niaid.nih.gov> Cc: Folkers, Greg (NIH/NIAID) [El <@niaid.nih .gov>; Conrad, Patricia (NIH/NIAID) [El <@nih.gov>; Routh, Jennifer (NIH/NIAID) [El <@nih .gov>; Lane, Cliff (NIH/NIAID) [El <@nih.gov> Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedi a.co m> Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias <@ikanamedia.com > Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg <@mail.nih.gov>, " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM <@niaid.nih.gov > this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM <@niaid.nih.gov > Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti <@noiaft.org> Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG <@niaid .nih.gov> Cc: NIAID COGCORE<@mail.nih.gov>, NIAID Media Inquir ies <@niaid.nih.gov> Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang <@sinobio logical.info> Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia <@la7.it> Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM <@niaid .ni h.gov> (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda <@paypal.com > Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay <@edelman.com > Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de > Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf <@syntacoll.de> Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf <@syntacoll.de> -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.<@nas.edu>; George (b)(6) ; Hannon, Emma <@nas.edu>; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael <@nas.edu>; (b)(6) Mun, Jenny <@nas.edu>; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau <@nas.edu >, Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" <@nas.edu> , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" <@cnn.com>, ------------- (b) (6) "Amanda. Sealy@cnn .com " <@turne r.com " <@turner.com >, (b)(6) "McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenn y" <@nas.edu>, CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.<@nas.edu>; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma <@nas.edu>; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael<@nas.edu>; (b)(6)> ; Mun, Jenny <@nas.edu>; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau <@nas.edu >, George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" <@nas.edu >, "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " <@cnn.com >, "Amanda.Sealy@cnn.com " <@turner.com " <@turner.com > , (b)( 6) "McGinni s, J.Mi chael" <@nas.edu >, ---------------- CbH6) >, "Mun, Jenny" <@nas.edu>, (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.<@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a <@nas.edu >; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. <@nas.edu> Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.<@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' <@cnn.com >; ---------'Amanda.Sealy@cnn.com ' <@cnn.com >; 'Neel. Khairzada@turner .com' <@turner.com >; 'Tia.Miller@turner .com' <@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie <@ncdps.gov> Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD (CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie <@fda.hhs.gov> Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John (NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/IO) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/IO) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/IO) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan (OS/ASPR/IO) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/IO) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/IO) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/IO) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/IO) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) <@mail.nih.gov> Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/IO) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence (NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John (NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo <@lastampa.it> Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat <@hivr4p.org> Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier <@ourpubl icservice.org> Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies <@ourpublicserv ice.org> Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. <@nas.edu> Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma <@nas .edu>; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' <@cnn .com>; 'Amanda.Sealy@cnn.com' <@t urner .com' <@turner .com> ; (b) ( >; McGinni s, J. Mic hael <@nas.edu>; (b)( (b)(6) ; Mu n, Jenny <@nas .edu>; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma <@nas.edu>; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' <@cnn.com' <@t urne r.com>; 'Tia.M iller@turner .com' <@turner.com >; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith <@one .org> Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart <@one.org> Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements <@niaid .nih.gov> Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman<@sanaria.com> Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden <@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C <@who .int> , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC <@who.int> , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC <@who.int>; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC<@who .int>; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i <@fortaleza.pr.gov> Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan <@prfaa.pr .gov>; Juan L. Negron <@fortaleza.pr.gov>; Antonio L. Pabon Batlle <@forta leza.pr.gov> Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park <@time.com> Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov>;Conrad, Patricia {NIH/NIAID) [El <@niaid.nih.gov> Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams <@caa.com> Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman <@caa.com> ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams <@caa.com> Cc: Christine Lancman <@caa.com>, (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams <@caa.com> Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman <@caa.com > Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recip ient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexual harassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl <@fnih.org> Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. <@nas.edu> Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan <@nas.edu> Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha <@calhacks.io> Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams <@caa.com> Cc: Christine Lancman <@caa.com >; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams <@caa.com> Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman <@caa .com> Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines <@nih.gov > Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali <@turner.com > Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines <@nih.gov > Cc: Cohen, Elizabeth <@turner.com >; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim <@global -infra.com> Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen <@rockfound .org> Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] <@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield <@uw.edu > Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld <@uw.edu > Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield <@uw.edu> Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis (NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz <@w ashingtontimes.com > wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.<@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny <@nas.edu > Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. <@duke.edu> Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General <@who.int> , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s <@resolvetosave lives.org>, "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC <@who.int>, "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine <@manuscriptcentral.com > Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" <@niaid.nih.gov > Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " <@nejm.org > Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de> Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf <@syntacoll.de> Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf <@syntacoll.de> Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf <@syntacoll.de > Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf <@syntacoll.de> Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM <@n iaid.nih .gov> Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton <@keystonesymposia.org> Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith <@one.org> Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart <@one.o rg> Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy <@bclplaw .com> Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith <@one.org> Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart <@one .org> Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe <@washpost.com> Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE<@mail.nih.gov> Cc: NIAID OD AM <@niaid.nih.gov> Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton <@keyston esymposia .org> Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) <@service.gov deli very.com > Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. (CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/IO) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/IO) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM <@ni aid .nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM <@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] <@niaid.nih.gov> Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]<@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [E] <@nih .gov>; Routh, Jennifer (NIH/NIAID) [E] <@nih.gov > Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/IOS) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie (NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton <@cpa -qc.ca> Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/IO) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner <@jamanetwork.org > Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa <@jamanetwork.org > Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner <@jamanetwork.org> Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r <@jaman etwork.org> Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM <@niaid.nih.gov> Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park <@ti me .com > Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews <@time.com > Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park <@time.com>w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana <@bizsecure .us> Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence (NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff <@whmo.mil> Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon <@mail.huji.ac.il> Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon <@mail.huji .ac.il> Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon <@mail.huji.ac.il> Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik <@neximmune .com> Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L <@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano <@asmusa.org> Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara (NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L<@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " <@list.nih.gov > Cc: List DEPDIR-L <@list.nih.gov >, NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole <@lewis -burke .com> Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby <@lewis-burke.com > Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" <@nbcuni.com> , Jeremy Schu lman <@schulmanbh.com > Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller <@schulmanbh.com> Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) <@knowledgeu.com> Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) <@knowledgeu.com>; Katie Dinsmore (kdinsmore@knowledgeu.com) <@knowledgeu.com> Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred <@washpost .com> Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter (NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC) [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@goog le.com > Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park <@immunemed .co.kr> Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. <@nas.edu> Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny <@nas .edu>; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma <@nas .edu>; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' <@cnn.com' <@t urner.com>; 'Tia.M iller@turner.com' <@turner.com>; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny <@nas.edu> Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' <@cnn.com>; 'Nee l.Khairzada@turner.com' <@turner.com' <@turner.com> Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney <@topspinconten t.com> wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn <@ap.org Date: Sunday, April 12, 2020 10 :56 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= > CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT<@state .co.us> Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias <@ikan amed ia.com>wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM <@niaid.nih.gov> Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon <@jsg.utex as.edu> Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall <@editoria lmanag er.com> Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley <@theatlantic.com> Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley <@theatlantic.com> Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX <@radio-canada.ca> Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" <@niaid .nih.gov>, "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE<@ma il.nih .gov>; NIAID OD AM <@niaid.nih.gov> Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante <@outlook.it> Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih.gov> Cc: Barasch,Kimberly (NIH/NIAID) [C) <@nih.gov>;Conrad, Patricia {NIH/NIAID) [E) <@niaid.nih.gov> Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC <@who.int> , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) <@resolvetosavelives.org > , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC <@w ho.int> , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) <@nia id .nih .gov> Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements <@niaid.nih.gov> Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line <@ors.od.nih.gov > Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@google.com> Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB <@mail.nih .gov> Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe <@joffeemergencyservices.com> Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: <@pnascentral.org> Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate (NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/IOS) CbH6)Shuy, Bryan (OS/ASPR/IO) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis (NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/IO) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NIH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/IO) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/IO) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/IO) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/IO) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/IO) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/IO) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/IO) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/IO) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/IO) CbH6)>;Callahan, Victoria (OS/ASPR/IO) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6)>;Windom, Robert (OS/ASPR/IO) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/IO); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/IO); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/IO); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/IO); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/OD); Windom , Robert (OS/ASPR/IO) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/IOS) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/IOS) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/IOS) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/IOS) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert <@pennme d icine.upenn.edu > Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando <@ma rianneorlando .com> Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs <@usc.edu> Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' <@nic.in >; Toomas (b)(6)>; GPMB Secretariat <@who.int >; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' <@nic.in >; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' <@nic.in >; Toomas Palu GPMB Secretariat <@who.int >; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak <@live.ca> Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s <@thetrek.co > Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam (NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani <@blood.ac. tz> Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" <@w ashpost.co m> Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar <@bobbleheadhall.com> Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary <@washpost.com> Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L <@list. nih.gov> Cc: NIH Director's Executive Committee <@mail.n ih.gov> Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " <@list.nih.gov > Cc: NIH Directo r's Executive Committee <@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 <@globalreporter.it > Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti <@milfo rd.nh.gov> Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G <@nytimes.com>wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar <@bobbleheadhall.com> Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: <@ny times.com> Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin <@arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." <@abgenics.in> Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich <@biosan itize.us> Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor <@b iosan itize.us" <@biosani tize.us> Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo <@optimumre .com> Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" <@the-times.co.uk > Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" <@mail.huji. ac.il> Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona <@canyonranch.com> Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker <@therimunex.com> Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona <@canyonranch.com > Cc: Patricia Maxwell <@canyonranc h.com >, "dgrange @osp reyg lobalsol utions.com" <@ospreyg lobalso luti ons .com > Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " <@myseneca .ca> Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie <@empowerme.e nterprises> Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden <@blindfish .media> Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue <@demiurge. technology >wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue <@demiurge.technology > Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco <@cn io.es> Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. De conformidad con lo dispuesto en el Reglamento (UE) 2016/679 relativo a la protecci6n de los datos personales de las personas ffsicas, la informaci6n personal que nos pueda facilitar a traves de este correo electr6nico quedara registrada por la Fundaci6n CNIO con la finalidad de tramitar el objeto del presente correo electr6nico . El tratamiento de sus datos personales se encuentra legitimado por ser necesario para gestionar el objeto del presente mensaje. Estos datos personales no seran comunicados a ningun destinatario salvo a aquellos que usted nos auto rice o asf venga exigido por una ley. Ud. podra NIH-000151 ejercer los derechos de acceso, rectificac i6n , supresi6n, limitaci6n de tratamiento , portabil idad y oposici6n en la siguiente direcci6n : c/Melchor Fernandez Almagro 3, 28029 (Madrid). Podra ponerse en contacto con el Delegado de Protecci6n de Datos en: delegado lopd@cnio.es. Para el caso de que Ud. precise conocer informaci6n adicional sobre el tratamiento de sus datos personales, puede consultar dicha informaci6n adicional en el siguiente enlace dentro de nuestra pagina web: https://www.cnio.es/es/privacidad/index .asp **LEGAL NOTICE**: This email and any attached files may contain protected information for the sole use of its intended recipient or addressee. Anyone other than the intended recipient or addressee is strictly prohibited from distributing , reproducing or transmitting the email and its contents in any way. If you receive this email in error, please notify the sender and delete the message. Pursuant to the provisions of EU Regulation 2016/679 regarding the protection of personal data, any personal information you provide through this emai l will be registered by the CNIO Foundation in order to deal with content of this email. Your personal data must be processed in order to be able to deal with the content and purpose of this message. Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L<@mail.nih.gov>; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM <@niaid .nih .gov>; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it <@libero.it> Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamedia.com> Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback <@ncbi.nlm. nih.gov> Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias <@ikanamedia .com> Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe <@frame.media > Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe <@frame.media >wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA)<@cell.com> Cc: Fauci, Anthony (NIH/N IAID) [E] <@niaid.nih.gov> Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) <@cell.com > Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA)<@cell.com > Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William <@apcoworldwide .com > Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore <@health.ucsd.edu> Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n <@health Subject: Re: George Church interview Date: March 24, 2020 at 12:09:20 PM PDT To: Jon Cohen <@aaas.org> NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen <@aaas.org> wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore <@ucsd.edu> wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC<@who .int> ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives <@reso lvetosavelives .org>; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC<@who.int>; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand <@rttv .fr> Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg <@n iaid .nih .gov>; NIAID COGCORE<@mail.nih.gov> Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC <@everb ri dge.net > Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen <@washpost.com > Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley <@washpost.com > Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams <@wamu.org > Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" <@niaid.nih .gov> Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " <@LIST.NIH .GOV> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson <@fannocreek .com> Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner <@jamanetwork.org> Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani <@jamanetwork .org> Cc: Edward Livingston <@jamanetwork .org> Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner <@jamanetwo rk.org>, Tony Fauci 6b , Preeti Malan i <@med.um ich.edu>, Eli Perencevich , Phil Fontanarosa <@jamanetwork.o rg> Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner <@jamanetwo rk.org> Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD) [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G <@nytimes.com> Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan <@georgetown.edu> Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) <@uidaho .edu> wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re <@health.ucsd .edu> wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" <@sriramachandra .edu.in> Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna <@ho lycross .bc.ca>wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D <@email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly <@aaas.org> Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard <@rwjf .org> Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis (NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila <@nyt imes .com > Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila <@nytimes .com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes .com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila <@nytimes.com> Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila <@nytim es.com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes.com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen <@b io- signal.com> Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila <@nyt imes.com> Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila <@nyt imes.com > Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John (NIH/OD) [E] (b)(6) CbH >; Fine, Amanda (NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@ny t imes.com > wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis (NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis (NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis (NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming <@nature .com> Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey <@bio.org > Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = <@bio.org> --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias <@ikanamedia.com > Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias <@ikanamedia.com> Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason <@wsj.com> Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE<@n iaid.nih.gov>; NIAID FOG<@niaid .nih .gov> Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/IO) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<@,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" <@FOXNEWS.COM> Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret <@FOXNEWS.COM> Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley <@FOXNEWS.COM>; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret <@FOXNEWS.COM> Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley <@FOXNEWS.COM> Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley <@FOXNEWS.COM> Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley <@foxnews.com >wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 <@foxne ws.com >wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis (NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar <@tytocare .com> Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson <@zrgpartners.com> Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson <@robinsonmanagementserv ice.com > wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y <@howard.edu> wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones <@winning-newsmedia.com> wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" <@turne r.com > Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian <@slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian <@slammiami.com> -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq <@jsgroup.com.kw> wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson <@med.cornell.edu>wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 <@columbi a.edu>; kathleen foley (b)(6); Carol Storey-Johnson <@med .corn ell .edu > Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/IOS);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/IOS);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy (OS/IOS) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/IO) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/IO) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/IO)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling <@literacymatters .education> Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley <@researchamerica .org > Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney <@resea rchamerica .org> Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah <@cbsnews.com> Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] <@cbsnews.com> Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah <@cbsnews .com> Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam <@cbsnews .com > Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu <@stanford.edu> Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" <@stanford.edu >, Amanda Chase <@sta nford.edu > Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe <@hms.harvard.edu> Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas<@bernstein.com > Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas <@be rnste in.com > Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas <@economist.com> Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas <@econ omist.com >wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly <@theceoforumgroup .com> Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller <@cbc .ca> Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke <@americamedia.org > Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 <@wolf lawyer.com> Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NIH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray <@mrc .ac.za> Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin <@hdltherapeutics.com> Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert <@steinmancommunications.com> Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur <@bio.or g> Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur <@bio .org> Cc: Jenni fe r Alton <@pathwaypolicy .com>, Ellen Carlin (bH6) >, Amy Walker <@bio.org>, Grego1yFrank ---------<@bio.org> Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone <@scripps.edu> Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada <@elconfidencial.com> Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah <@bmc .org> Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" <@scientekpower.com> To: (b)(6) Reply-To: <@scientekpower .com> Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm <@kammconsultinginc.com> Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) <@msnbc .com> Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison <@csis .org> Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman <@csis.org> Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison <@cs is.org > wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra <@abc.com> Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra <@a bc.com > > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/IO) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/IO) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/IO)" (b)(6) "Hamel , Joseph (OS/ASPR/IO)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/IO)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/IO) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/IO) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (OS/ASPR/IO) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/IO) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/IO); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/IO) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/IO); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/IO); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/IO) (b)( >; Hamel, Joseph (OS/ASPR/IO) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/IO)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/IO) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/IO) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/IO) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/IO): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t (OS/ASPR/IO) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/IO) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/IO): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/IO): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/IO): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/IO): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/IO) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/IO) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/IO) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/IO) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/IO)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan (OS/ASPR/IO)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan (OS/ASPR/IO) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) (OS/IOS)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/IO) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/IO) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/IO)" (b)(6), "Yeskey, Kevin (OS/ASPR/IO)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/IO)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/IO) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/IO) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/IO) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/IO) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List <@LISTSERV .CDC.GOV> On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen <@was hpost .com> Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F.<@Kennedy-Center .org> Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary <@Kennedy-Center .org> Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul <@thaiembdc.org> Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya <@thaiembdc .org> Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara (NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <@vox.com>wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM <@niaid.nih .gov> Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling <@thedocumentarygroup .com> Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/OD);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas <@airlines.org> Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg <@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) <@bloomb erg .net>wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) <@bloomberg .net> Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci <@businesscouncil.com> Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball <@businesscoun cil.com >; Gillian Auger <@bus inesscounc il.com > Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci <@businesscouncil.com> wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci <@businesscouncil.com > Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg <@eng.us> Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov> Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg <@ama -assn.org> Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM <@niaid.nih .gov> Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM <@niaid.nih .gov> Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison <@csis.org> Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll <@csis.org>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman <@pl et te r .com> Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ <@stimes.cn> Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal <@mai lonline .com> Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero <@pazienti.it> Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza <@pazienti.it> Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" <@wtop .com > Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses <@usasiainstitute .org> Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine <@trilateral.org> Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig <@tr ilateral.org> Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M.<@abc.com> Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan <@cbsnews.com > ; Jay Shaylor <@cbsnews.com > Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim <@cnn .com > Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) <@zeemedia.esselgroup.com> Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) <@zeemedia.esselgroup (W 10 .com> Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) <@zeemed ia.esselgroup.com >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) <@zeemed ia.esselgroup .com > Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <@zeemed ia.esselgro up.com> Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) <@zeemed ia.esselgrou p.com >; KUMAR SUNNY <@zeemedia.esselgroup.com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) <@zeemed ia.esselgroup.com > Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) <@zeemed ia.esselgrou p.com > Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemed ia.esselgroup. com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) <@zeemedia.esselgroup.com> Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) <@zeemedia.esselgroup.com> Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgroup .co m> Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) <@zeemedia .esselgr oup.com > wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgro up .com > Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) <@zeemed ia.esselgroup.com > Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations<@zeemedia.esselgroup.com> Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" <@turner.com > Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " <@turner .com> Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle <@turne r.com> Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle <@turner .com > wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle <@turner.com > Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle <@tu rner .com> wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle <@tu rner .com> Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle <@turne r.com > Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo <@kff.org> Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" <@turner.com > Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie <@turner .com> Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) <@turner .com> Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) <@turner .com> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <@turner .com> wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner .com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) <@turner .com > wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) <@turner.com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner.com > wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) <@turner .com > Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@turner .com > Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" <@turner.c om >, "Lovejoy, Hannah NIH-00203 1 (NE)" <@turn er .com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve<@cowen .com> Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil <@cowen.com>; Nedelcovych, Michael <@cowen.com> Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" <@tumer.com >, "Lovejoy , Hannah (NE)" <@tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) <@turner.com> Cc: Pfeifer, Hazel <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) <@turne r.com>wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@t urner .com >; Lovejoy, Hannah (NE) <@turner .com >; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) <@turne r. com>wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner .com>; Lovejoy, Hannah (NE) <@turne r.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner .com >wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) <@turner .com > Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) <@turner.com> Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" <@turner.com > , "Lovejoy , Hannah (NE)" <@turner.com > Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias <@ikanamed ia.com> Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae <@wtop.com> Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae <@wtop.com > Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal <@wtop .com> wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" <@wtop .com> Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal <@wtop .com > Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM <@niaid .nih .gov> Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle <@turner.com> Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" <@FOXNEWS.COM> Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra <@FOXNEWS.COM> Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra <@foxnews.com > wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram <@medpagetoday.com> Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano <@buzzfeed .com> Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda <@gannett.com> Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner <@jamanetwork.org> Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor <@ama-assn .org > Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork.org >, Annette Flanagin <@jamanetwork.o rg>, Michae l Berkwits <@ama-assn.org >, Brian Shields <@ama -assn.o rg>, Sean O'Donnell NIH-002097 <@ama-assn.erg> Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner <@jamanetwork.org> Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r <@ama - assn.org> Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork .org >, Annette Flanag in <@jamanetwork.org >, Michae l Berkwits <@jamanetwork.org >, Tom Easley <@ama -assn.org >, Brian Shields <@ama -assn.org >, Sean O'Donnell <@ama-assn .org > Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/OD);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb <@gmai l.com> wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner <@jamanetwork .org> Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner <@jamanetwork.org> Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner <@jamanetwork.org> Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner <@jama netwo rk.org> Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner <@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner <@jamanetwork.org >; Phil Fontanarosa <@jamanetwork.org > Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth <@turner.com> Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons <@t hehill .com> Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq <@ntv.ru> Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee <@bbc.co.uk> Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" <@mail.nih.gov>, "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/IOS); Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD) [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/IOS) (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/IO) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/IO) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) <@HHS.GOV> Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/IO) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/IO) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/IO) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil (NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis (NIH/OD) [El (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/IOS) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/IO) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10<@hhs .gov>; ASPRExec Sec (OS/ASPR)<@hhs .gov> Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas <@t heat lant ic.com > Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/IOS); Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD) [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/IOS) (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <@hhs .gov > Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" <@hhs.gov > Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral <@hhs.gov > Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral <@hhs.gov > Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. <@nejm.org>wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@ne j m.org> --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org > Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. <@nejm.org >wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@nejm.org> Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. <@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.o rg> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY <@ahaber .com .tr> _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil (NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile (NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis (NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ (NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci <@businesscouncil.com> Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein <@carly le.com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani <@ipsos.com> Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit <@v oanews.com > Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm.o rg> Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.<@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. <@nejm .org > Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller <@cbc.ca> Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. <@nejm .org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner <@jamanetwork.org> Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin <@jamanet w ork .org>; Christiansen, Stacy <@jama network .o rg>; Demetrios Kyriacou <@i amanetwo rk .o rg>; Edward Livingston CbH6>>; Fontanaros, Phil <@jama-archives.org >; GoIub, Robert <@jama-a rchives.org>; Gregory Curfman --------------- NIH-002241 <@jama-archives.org ; Jody Zylke <@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits <@jamanetwork .org>; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <@jamanetwork.o rg>; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub <@jamanetwo rk.org>; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ <@niaid.nih .gov> Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) <@n iaid .n i h,gov > Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamed ia.com > Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias <@ikanamedia .com> wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) <@zeemedia.esselgroup.com> Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations <@zeemedia.esselgroup.com> Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] <@niaid .nih .gov> Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth <@aspenin stitute.org> Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth <@aspenin stitute.org> Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth <@aspeninstitut e.org> -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth <@aspeninstitute.org > Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth <@aspenin stitute.org > Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth <@aspenin stitute.org > Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth <@aspeninst itute.org >> Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth <@aspen institu te.org >> Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org <@aspen insti tute.org > 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle <@th irteen.org> Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <@bloomberg .net > Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica <@ansa.it> Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca <@npr.org> Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM <@niaid.n ih.gov> Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED <@afp.com > Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) <@nbcuni.com> Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) <@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) <@n bcun i .com> wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) <@nbcuni. com > Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis (NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis (NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci <@businesscouncil.com> Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein <@carlyle .com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail <@gmail.com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ (NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." <@cbsnews.com> Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" <@n iaid.nih.gov> ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" <@b iode fensecomm ission .org > Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George <@biodefe nsecomm issio n.o rg> Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George <@b iodefen secomm ission.o rg> Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" <@bio defe nsecomm ission .o rg > Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George <@b iode fensecomm issio n.o rg> Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " <@b iode fensecomm issio n.o rg> Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov <@hhs.gov > Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov <@hhs .gov > Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov <@HHS.gov> Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis (NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Sent: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc:Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From : Muniz, Maria de Los Angeles <@vitalant.org> Se nt : Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject : National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Sent: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global <@gl oba ldownsynd rome.org> Sent: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk <@globaldownsyndrome .org>; Marisa Cucuzzella <@ajsfoundation .com>; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Sent : To : Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Sent: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Sent: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From : (b)(6) Sent : Wednesday, March 4, 2020 5:46 PM To : Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject : Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To : Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Sent: (b)(6) From: Aliantha Angel (b)(6) Sent: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject : Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Sent: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From:Gordon, Joshua (N IH/NIMH) [El Sent : Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject : Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.<@abc.com> Sent: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject : Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Sent: To : Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From:RichSilverman Sent: Wednesday,March 4, 2020 8:56 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To : Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Sent: Wednesday, Marc h 4, 2020 6:59 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Sent: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject : Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Sent: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From:Steve Black Sent: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen <@cepi.net> Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Sent : Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To : Subject : Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park <@time.com> Sent : Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject : TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Sent : To : Subject : (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To : Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Sent: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From : Fauci, Anthony (NIH/NIAID) [E] Sent : Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject : RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Sent: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Sent: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Sent : Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Sent: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject : FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From : Johnson, Christie <@turne r.co m> Sent : Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject : Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From : Johnson, Christie Se nt: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject : CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie <@t urner .com > Sent: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Sent : Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject : CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From : KUMAR SHAH, MD (b)(6)> Sent : Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject : Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To : Siegel, Marc Subject : RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc <@nyulangone.org> Sent: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser <@patientsafetymovement .org> Sent : Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay <@patientsafetymovemen t .org> Subject : COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Se nt : Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To : Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject : How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Se nt : Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Sent : Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject : my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Sent : Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject : Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Dat e: March 3, 2020 at 1:35:53 PM EST To: SHOC <@who.int>, "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) <@resolvetosavelives.org>, , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Se nt: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subje ct : Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Sent: (b)(6) To : Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey <@jesuits .org> Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : expand@omcasa .com <@omcasa .com> Sent : Tuesday, March 3, 2020 5:00 AM To : Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Sent : To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From : El Bcheraoui, Charbel Se nt: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subjec t: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Sent: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Sent: To: Subject : Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From : Lily Carnie (b) ( Sent: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Sent: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject : Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Sent : To: Subject : Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Se nt: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) <@sky.uk> Sent : Tuesday, March 3, 2020 6 :16 AM To : Fauci, Anthony (NIH/NIAID) [El Subj ect : Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Sent : Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Sent: To : Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Sent : To: Subject : I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Sent: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" <@wsj .com > Date : Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject : Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Sent : To: Subject : hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Sent: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subj ect : Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date : March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Sent: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Sent: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Sent: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Sent: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject : Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi <@wsj.com> Sent : Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject :? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Sent: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan <@cbsnews.com > ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Sent : (b)(6) To : Subject : Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay <@pitt.edu >wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay <@pitt.edu>wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Sent : (b)(6) To : Subject : Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Sent : Mon, 2 Mar 2020 10:43:27 +0000 To : Marston, Hilary (NIH/NIAID) [El Subject : FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From:Amel ie RIOUX Sent: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Sent : Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Sent : To: Cc: (NIH/NIAID) [El Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Sent : Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject : Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Sent : Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject : Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Sen t: Sunday, March 1, 2020 2:46 PM -----~ ~ To : Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date : Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject : Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick <@statnews .com> Sent : Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject : Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Sent : Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From : Sent : Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To : ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : pascal goldschmidt __________ Sent : Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subj ect : (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Silverberg, Kristen <@brt.org> Sent: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Sent: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Sent: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Sent : Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject : Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi update: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi update: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Sent: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari <@scripps.edu> Sent: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST<@utsouthwestern .edu>; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone <@scripps.edu>; Eckard Wimmer <@stonybrook.edu> Cc: Charles Rice <@scripps.edu> Subject : (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Sent : Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject : SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily <@americanchemistry .com> Sent: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From:Thomas Murray Sent: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Sent : To: Subject : You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Sent : Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Corey MD, Larry _______ Sent: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To : Subject : Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Sent: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From:Jeffrey V. Ravetch Sent : Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject : Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Sent: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject : (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sun, 1 Mar 2020 19:22:37 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Jim Iversen (b)(6) Sent: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Sent : Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To : Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Sent: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc:Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From:Sharon Eblen sent: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Sent: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To : Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai <@npr.org> Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai <@npr .org> Sent: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc:Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai <@npr .org> Sent: Thursday, February 27, 2020 2:09 PM To : Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Se nt : Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject : Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From : "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Sent: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Sent: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From:Bob Franken-------~ (b-)~(6) => > Sent: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From:Collins, Francis (NIH/OD) [El Sent: Wednesday, Febru ary 26, 20 20 7:59 AM To : M ichael Milken (mm ilken@knowledgeu .com) <@knowledgeu .com> Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From : Conrad, Patricia (NIH/NIAID) [E) Se nt: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject : Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From : "Blackburn, Amy (NIH/OD) [El" Date : February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject : RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Sent: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. <@fhn.org> Sent: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Sent : Thursday, February 27, 2020 9:07 AM -------------- To : Fauci, Anthony {NIH/NIAID) [E] Subj ec t : ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From : Winnie Stachelberg <@americanprogress.org> Sent: Thursday, February 27, 2020 8:02 AM --------, To : Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject : RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From : Winnie Stachelberg Sent : Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject : FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From : Steve Bonitatibus <@americanprogress.org > Se nt : Thursday, August 15, 2019 11:21 AM To: Posted Products <@ame ricanp rogress.org> Cc: Kyle Epstein <@ame ricanprogress.org>; Daniella NIH-001111 Leger <@americanprogress.org > Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From:Howard Schatz Sent : Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject : Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik <@npr.org > Sent: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Sent: To: Subject : Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Sent: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To : Subject : That number seems exceptionally high. From: Strauss, Eric M . <@abc .com> Se nt : Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Se nt: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Sent : To: Subject: Let us discuss. From : Sabrina Ma lhi <@thehill .com> Sent: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi <@t hehi ll.com > Sent: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Sent : To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Sent : Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subjec t : Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From : Barry Coller (b)(6)> Date : February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc : Barry Coller ----------- (b)(6) Subje ct : Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From:Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM <@niaid .nih .gov> Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen <@brook ings.edu> Sent: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim <@brookings.edu> Subject : Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Sent: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Sent: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject : RE: Sent: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : B arton Haynes , M.D. Sent: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Sent : Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Sent: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From : Barton Haynes , M.D. Sent: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject : RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Sent: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Sent: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Sent: Saturday, February 29, 2020 11:03 AM To : -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject : Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To : Subject : RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Sent : Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject : in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Fred Schaich <@ifaratv.org > Sent: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Sent: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Sent: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Sent : To: Subject : Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Sent : Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Sent: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Les Gardonyi (b)(6)> Sent: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject : Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Sent: Sat, 29 Feb 2020 23:54:27 +0000 To : Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Sent: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu <@protherimmune.com> Sent: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang <@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subjec t: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From : Tom Leopold (b) (6) Sent : Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From : Tom Leopold (b) ( Sent: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman <@ohsu .edu> Sent : Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Se nt: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To : Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject : Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Sent: To: Subject : (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From:Tabak, Lawre nce (NIH/OD) [El Sent: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc:Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From : Samant ha Mauro ------------- (b)( 6)> Sent: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject : Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Sent: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" <@cdc.gov> , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Sent : To: Subj ect : ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Gere diZerega Sent : Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subj ect : Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Sent: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Sent: (b)(6) To : Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan <@theatlantic.com> Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Sent: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander <@rttv.ru> Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Sent: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subje ct: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Sent: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From : Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From : Allison Ogdon <@keystonesymposia.org> Sent: Friday, February 28, 2020 12:10 AM To : Allison Ogdon <@keystonesymposia.org> Cc: Heidi Daetwyler <@keystonesymposia .org> Subject : Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From:Kline, Lydia (NIH/OD) [El CbH6J> Sent : Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Sent: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Sent : Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc : Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From : Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject : Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Sent: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject : Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Sent: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From:Jose Alcami Pertejo <@isciii .es> Sent: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc:Jose Alcami Pertejo <@isciii.es> Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From:Conrad, Patricia (NIH/NIAID) [El Sent: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady <@economicclub.org> Sent: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza <@economicclub.org> Subject : David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Se nt: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Se nt: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Sent: To: Subject: FYI. Does this deserve a response. From:Nejat Duzgunes (b) (6) Sent: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Sent : Thursday, February 27, 2020 2:03 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject : RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Sent : To : Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments <@hms.harvard.edu> Sent : Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara <@hms .harvard .edu>; Tekleab, Sarah <@hms.harvard .edu> Subject : Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Sent : To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai <@npr .org> Se nt: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject : Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Sent: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc:Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject : FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Sent : Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Sent: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Sent: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subj ect: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Sent: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra <@abc.com> Sent: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Sent: To : Cc: Subject : Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park <@time.com> Sent : Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject : Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park <@t ime.com> wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject : RE:URGENT Sent: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Sent: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Se nt : Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David <@aaaai.org>; Rebecca Brandt (AAAAI) <@aaaai.org> Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Sent : To: Subject : Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie <@nas.edu> Sent: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject : Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From : Jon Coh en <@aaas.org> Sent: Thursday, February 27. 2020 5:48 PM To : Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Sent: To : Cc: Subject : by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Sent: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" <@spglobal.com> Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" <@niaid.nih.gov>, "My les, Renate (NIH/OD) [E]" (b)(6) Subject : Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Sent : Thursday, February 27, 2020 6:55 PM To: Young, Donna <@spglobal. com> Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject : Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" <@spglo bal.com > Date : Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" <@niaid .nih .gov>, "My les, Renate (NIH/OD) [E]" (b)(6)> Subject : Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Sent: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna <@spg loba l.com > Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) <@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" <@spg loba l.com > Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Sent: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih .gov>; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To : Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Sent: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Sent : Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject : _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Sent : (b)(6) To : Subject : Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To : "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia <@imf.org> On Behalf Of Gopinath, Gita Sent : Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita <@imf.org>; Milesi -Ferretti, Gian Maria ; Celasun, Oya <@imf .org>; Christiansen, Lone Engbo <@imf.org> Subject : Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject : Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Sent : Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC <@who .int>; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject : The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Sent: To: Subject : FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) <@m snbc.com > Sent: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) <@msn bc.com > > Sent: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject : Please set this up. Thanks. From:Fox, Lauren <@turner .com> Sent: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject : Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Sent : To : Subject : Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Se nt: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject : My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James <@wsj.com> Sent : Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject : Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Sent: To: (NIH/NIAID) [E] (b)(5) Thanks . From:Marston, Hilary (NIH/NIAID) [E] (b)(6)> Sent: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" <@hhs.gov> Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To : Subject : 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Sent: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Sent: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Sent : To : Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Se nt: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject : RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Sent : Monday, March 2, 2020 8:14 PM -------=-=-=- To : Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject : Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From : "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject : RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Sent : Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject : Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc:"Stee le, Danielle (HHS/10S)" ---------Subje ct: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Sent : Thursday, February 20, 2020 12:19 PM To : Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject : Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Sent: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject : FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Sent : To : Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Se nt: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject : RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Se nt: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Sent: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Sun, 1 Mar 2020 22:35:38 +0000 To : Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Sent: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Sent: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Sent: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To : Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Sent : Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Sent: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Sent : To : Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) sent: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject : Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Sent: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Sent: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject : mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject : RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Se nt: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject : FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From : Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Sent : Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Sent : To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Sent: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Sent: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Sent: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Sent: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From : Laura Landerman-Garber Sent : Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject : Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Sent: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " <@nia id.nih.gov > Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From : Sent : To: Subject : Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From : LOUIS FORTUNATO Sent : Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject : Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject : Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date : February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From : LOUIS FORTUNATO (b)(6)> Subject : HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date : November 3, 2019 at 5:11:19 AM EST To : (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Sent: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Sent: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" <@wtop .com > Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" <@wtop.com > Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Sent: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To : Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" <@wtop.com > Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From:Anderson, Liz Sent: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura <@wtop.com> Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Sent: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett <@nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Sent : To : Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject : RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth <@nejm .org> Sent : Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject : RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Sent : Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth <@nejm.org> ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject : RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth <@nejm .org > Sent: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Sent: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org > Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject : RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth <@nejm.org > Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subj ect : NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Sent: To : Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams <@nationalpress.org> Sent : Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Sent : (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth <@nejm.org> Se nt : Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject : RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From : Laurencot, Elizabeth Sent: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject : RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Sent: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth <@ne jm .org> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject : RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org > Sent : Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject : NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Sent : To : Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Sent : Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti <@bbc.co .uk> Sent : Wednesday, February 26, 2020 11 :47 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject : RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Sent : Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject : Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Shannon Williams <@sibf.org> Sent: Wednesday, February 26, 2020 11:10 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) <@nbcuni.com> Sent : Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject : MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Sent : To: Subject : See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth <@nejm.org> Sent : Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject : RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Se nt: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth <@nejm .org> NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject : RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm .org> Sent : Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Sent : Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject : First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Sent: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To : --------- Cc: Subject : I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Sent: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : Fro m: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Sent : To: Cc: (NIH/NIAID) [El Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Sent : Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject : FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Sent : (b)(6) To : Subject : Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To : Tom Frieden (b)(6) Subject : A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Sent: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Sent: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Sent: Wed, 26 Feb 2020 10:59:30 +0000 To : *'@ ~ Subject : RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ <@thepaper.cn> Sent: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Sent: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" <@turner .com > Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From : Jon LaPook ,,;::;... ---~ (b ~)~(= > Sent: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Sent: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To : Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G <@nytimes.com>w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Sent: (b)(6) To : Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton <@theasiagroup.com> Sent : Tuesday, February 25, 2020 10:59 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Sent: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" <@msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Sent: (b)(6) To : Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) <@tum er.com >wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" <@turner.com> Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) <@turner .com> Sent: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please NIH-001355 notify the sender by return e-mail and delete it from your system . You shou ld not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email includjng any attachment s may be privileged or confidential and is intended exclusively for the addressee . The views expressed may not be official policy , but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce , distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertaimnent Networks International Limited (Company No. 2803512), Turner Broadcas ting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House , 16 Great Marlborough Street, London Wl F ?HS. NIH-001356 From: Sent: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike <@wtop.com> Sent : Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Sent: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject : Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Sent : (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Sent : Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject : RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Sent: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Sent: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" <@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" <@siriusxm.com> Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To : Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject : RE: Coronavirus vaccine From : Sent: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> sent: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Sent : To: Subject : variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Sent : Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject : Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth <@nejm.org> Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Laurencot, Elizabeth <@nejm.org> Sent : Tuesday, February 25, 2020 8:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To : Subject : Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Sent : Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks <@resolvetosavelives.org> __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC<@who .int>; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject : The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Sent: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" <@b loomberg .net> Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" <@nia id.nih.gov> Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" <@bloomberg.net> Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley <@bdo.com> Sent: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota <@bdo.com> Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Sent: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Sent: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Sent : Monday, February 24, 2020 6:03 PM ------------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Sent: To : Subject : COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Dweck, Kristen <@hsph.harvard .edu> Sent : Monday, February 24, 2020 5:34 PM To : Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject : Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From : Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Sent : To: Subj ect : W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Sent : Monday, February 24, 2020 4:04 PM To : Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject : RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 F r o m: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subjec t : RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@b loombe rg.net> Sent: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From : Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloom berg .net> Sent: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To : JASON GALE CC: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloo mberg .net > Sent: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] <@nih.gov> Cc: Routh, Jennifer (NIH/NIAID) [E] <@nih .gov > Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From : 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloombe rg.net> Sent: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net> Sent: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From : (b)(6) At: 01/17/20 03 : 22 : 49 To : Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc : (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) <@b loo m berg . net > Sent: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) <@bloomb erg . n e t > NIH-001410 Sent: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 F rom : )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To : Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subj e ct : Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Sent: To: Subject : NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From : DANIEL GAGNON Sent: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Sent : To: Subject : Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI <@nytimes.com> Sent : Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Sent : To: Subject : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Se nt: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subjec t : ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked to: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Sent : To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Sent: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Sent : To : Subject : You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Sent : Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject : ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To : Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject : RE: Interview Request from China From: Sent : Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Faye Li (b)(6)> Se nt: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Sent: Monday, February 24, 2020 10:46 AM To : Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject : FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Sent: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Sent: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine <@ma nuscriptcentral. com> Sent : Monday,Febrnary 24, 2020 10:00 AM To : Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subj ect: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subjec t: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Sent: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc : Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Sent : To : Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Sent : Monday, February 24, 2020 8:54 AM To : Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc : Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Sent : Monday, February 24, 2020 6:45:07 AM To : Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc : Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject : RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From : Myles, Renate (NIH/OD) [E] (b)( Se nt: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject : RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From : Fauci, Anthony (NIH/N IAID) [E] ______ Sent : Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Sent: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc : Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Sent: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Sent: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloombe rg.net > Sent: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subje ct: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From : John Lauerma n (BLOOMBERG/ NEWSROOM:) <@b loomberg.net> Sent: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject : Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject : FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Sent: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Sent: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject : Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date : February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Sent : Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Sent : Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Se nt: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subj ect : RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Gatti, Philip (b)(6) Sent: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Tabak, Lawrence (NIH/OD) [E] (b)(6) Sent : Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject : Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From : Fauci, Anthony (NIH/N IAID) [El (b)(6) Sent : Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . Fro m : Tabak, Lawrence (NIH/OD) [El Sent: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject : Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Sent: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Sent: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Wed, 26 Feb 2020 18:25:04 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Sent : Wednesday, February 26, 2020 1:12 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From : Brennan, Patrick (05/ASPA) Sent : Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc : ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject : For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject : Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From : "Brennan, Patr ick (OS/ASPA)" Date : Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" <@hhs.gov>, "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Sent: To: Subject : Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Sent: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Sent : To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Sent: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject : Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Dat e: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" <@hhs.gov >, "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From : Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Se nt : Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date : Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From : Kadlec, Robert (OS/ASPR/I0 ) Se nt: Monday, February 24, 2020 10:19 PM To : Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject : 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From : Moughalian, Jen (HHS/ASFR) Sent : Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject : RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From : Fauci, Anthony {NIH/N IAID) [El (b) ( > Se nt: Monday, February 24, 2020 1:42 PM To : Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Sent : Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Sent: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih .gov > Sent: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] <@mail.nih.gov >; Collins, Francis (NIH/OD) [E] <@nih .gov>; Gilman, James (NIH/CC/OD) [El <@n ih.gov > Cc: Burklow, John (NIH/OD) [E) <@od .nih .gov >; Hallett , Adrienne (NIH/OD) [E) <@nih.gov >; Billet, Courtney (NIH/NIAID) [E) <@nia id .nih .gov>; Davey, Richard {NIH/NIAID) [E] <@cc.nih.gov >; Cohen, Justin {NIH/CC/OD) [El <@nih .gov > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Sent: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject : FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject : Please handle. ---------------- From: Sent : Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Sent: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Sent: To : Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Jon LaPook ,,;:;-----~ (b~)~(6) = Sent: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From:Jon LaPook ,.:::;...----. (b ~)~(6) = Sent: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Sent: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Sent: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sun, 23 Feb 2020 15:56:48 +0000 To : Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Sent: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From : john won (b) (6) > Sent: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Sent: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subje ct: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From:Julia Belluz <@vox.com> Sent : Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject : Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz <@vox.com > wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Sent : Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subjec t : Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Sent: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Sent : Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject : FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Sent : Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Se nt: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Sent: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Sent: To : Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Sent: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject : RE: interview request: draft responses for Greek newspaper From: Sent: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Sent : Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG <@niaid.nih.gov > Cc: NIAID COGCORE<@niai d.nih .gov> Subject : int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From : Sent : To : Subj ect : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From : Cassett i, Cristina (NIH/NIAID) [El Sent : Saturday, February 22, 2020 2:26 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject : Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject : HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From : Sent : To: Subject : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Cassetti , Cristina (NIH/N IAID) (E] ---------Sent : Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject : Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date : February 18, 2020 at 3:07:21 PM EST Subject : HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Sent : To : Subject : Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Se nt : Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject : Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Sent: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Sent: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Sent: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From : Schneider, Johanna (NIH/NIAID) [El Se nt : Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject : For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Sent: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject : Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To : Cc: Subject : Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci <@businesscouncil.com> Sent : Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject : Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----Fr om: JF K (b) (6) Sent : Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Sent : To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen <@iasusa .org> Se nt: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen <@iasusa .org>; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject : RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Sent : Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen <@iasusa .org >; Barie, Toni C _________ _ <@iasusa.org >; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject : Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane <@:.. ____ (b) (b)(6) (b _ )_(_. 6>;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" <@t..,_____ Cb _)_@ ... wrote: Dear Ken, The (b) (6) . Committee greatly appreciatesyour willingnessto approach Dr. Anthony Fauci on our behalf, asking him to address the residents of the----,---, (b) (6) on the Coronavirus. It would perhaps be hel ful to Dr.Fauci, to ex lain who we are and what we do. (b) ( , (b)(6) The (b) ( Committee was ormed recently to create and orgamze events to e ucate, enlighten and entertain members of the Somerset community.A few weeks ago (b)(6) spoke to a sold out crowd on impeachment. We've featured authors on a variety of topics; invited doctors with specialtiesof interest to our communityorganized trips to the KennedyCenter and theaters for attendanceat ballets and plays and sponsored visits, led by experts, to various museums and the Library of Congress to view special exhibitions. An example of the latter is a tour of the Folger Library (b) (6). A presentationby Dr. Fauci on the coronaviruswould be of great interest to our constituencywho keep informed by reading both national and internationaljournals. We are flexible on the date for such an appearanceneeding only a few days' notice to inform our residents. I need not tell you that it wou ld our great honor to welcome Dr. Fauci to the NIH-001660 (b) (6):. Sincerely (b)(6) NIH-00166 1 From: Sent : To : Cc: Subject : Eastern Daylight Time I totally agree. Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 12:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E) Marston, Hilary (NIH/NIAID) [E);Barasch, Kimber ly (NIH/NIAID) [CJ RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM I do not want to be on a "session planning" call. Please have Hilary do this as suggested by Patty since she is preparing t he talk . T hanks. From: Conrad, Patricia (NIH/NIAID) [E) Sent : Friday, February 21, 2020 4:44 PM To : Folkers, Greg (NIH/NIAID) [E] (b)( 6) ---------------~~ --------- (b)(6) (b)(6Jr>;Fauci, Anthony (NIH/NIAID) [El Subject : FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Sent : Friday, February 21, 2020 4:37 PM To : Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Sent : Friday, February 21, 2020 6:14 PM To : Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject : DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Sent : To : Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From:Garen, Alan (b)( > Sent: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From:Antoniak, Cynthia {NBCUniversal, MSNBC) <@MSNBC.COM> Sent: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) <@nbcuni.com>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Sent : Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From:Antoniak, Cynt hia (NBCUniversal, MSNBC) <@MSNBC.CO M > Sent : Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) <@nbcun i.com >; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Sent: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM >; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Sent: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} <@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Sent: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) <@M SNBC.COM > Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent : Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject : [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) <@nbcuni.com > Sent : Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject : RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent : Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject : [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Sent: Friday, February 21, 2020 10:29 AM To : Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From : Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject : CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Goldner, Shannah (NBCUniversal) <@nbcuni.com > Sent : Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject : RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From : Conrad, Patricia (NIH/NIAID) [E) Sent : Thursday, February 20, 2020 4 :16---------- (b)( PM To : Goldner, Shannah (NBCUniversal) <@nbcuni.com > Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject : [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcuni .com> Sent: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject : hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject : Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" <@MSNBC.COM> Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" <@nbcun i.com>, "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject : MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) <@n bcuni.com> Sent: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc:Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM>; Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject : [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC)<@MSNBC.COM> Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc:Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Sent: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject : [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject : RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Sent: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject : [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Sent: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject : FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Sent: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Sent: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Sent : (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From : Billet, Courtney (NIH/NIAID) [E] Sent: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject : RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Sent: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject : Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Sent : To: Cc: Subjec t: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Sent: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Sent: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Sent: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie <@iasusa .org> Subject : RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa .org > Sent: Tuesday, February 18, 2020 8:09 PM To : Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen <@iasusa .org> Subject : RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Sent : To : Subject : Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Sent : Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject : FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Sent : To : Subject : Attac hment s: Pleasehandle. From : RICK SAWAYA (b)(6)> Sent : Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject : Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject : Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Sent : To: Subject : Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen <@iasusa.org> Se nt: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject : RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From : Fauci, Anthony (NIH/N IAID) [E] Sent : Thursday, February 20, 2020 7:12 AM To : Donna Jacobsen <@iasusa .org > Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie <@iasusa.org> Subject : RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen <@iasusa.org> Sent : Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen <@iasusa.org> Subject : RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From : McNei l Jr, Donald G <@nytimes.com> Sent : Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G <@nyt imes.com> wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Sent : Thursday, February 20, 2020 6:57 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang <@caixin.com> Sent : Thursday, February 20, 2020 3:16 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject : Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Achenbach, Joel <@washpost.com> Sent: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel <@washpost.com> Subject : RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel <@washpost Sent: Thu rsday, February 20, 2020 5:51 PM .com > NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject : quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Sent: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Sent: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } <@niaid.nih.gov> Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Sent: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Sent : Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject : GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Sent : To: Subject : Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From:Sharon Rockefeller <@we ta.org> Sent : Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Thu, 20 Feb 2020 00:54:10 +0000 To : Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Sent: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman <@biocentury .com> Sent : Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Sent: To: Cc: Subject : Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Crow, Hilary <@USChamber.com> Sent: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Sent: To : Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Marston, Hilary (NIH/NIAID) [E] (b)(6)> Sent : Wednesday, February 19, 2020 10:09 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject : Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM <@niaid .nih.gov > Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From : Feng Zhao <@wor ldbank.org > Sent: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla <@worldbank .org>; Rocio Schmunis <@worldbank .o rg>; Gabrielle Lynn Williams <@worldban k.org>; Muhammad Ali Pate <@worldba nk.org> Subject : Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Sent : To: Subject : Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Sent: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc : Andrew (b) (6J> Turl ey (b)(6)> Subject : Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall <@scgcorp.com> Sent: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM <@n iaid. n i h.gov>; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria <@scgcorp.com>; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa <@scgcorp.com>; Megan Schartner <@scgcorp .com> Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention <@crit icalment ion .com> Sent: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To : bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject : RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From : Br iana Doherty <@manu scriptcentral.com > Sent : Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. 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The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Sent: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Sent: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Sent : Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To : Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject : FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Sent : Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject : Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From : Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM <@niaid.nih .gov> Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen <@iasusa.org > Date : February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ <@iasusa.org > Subject : RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Sent: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon <@aacr.org> Sent: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To : Subject : Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine <@manuscriptcentral.com> Sent: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Sent: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Sent: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Sent: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <@o d. ni h.gov> Cc: NIAID COGCORE<@niaid .nih .gov> Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subjec t: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Sent: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc : Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Sent: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc:Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg <@mail.nih .gov> Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From:Venigalla B Rao [mailto:, Cb) (6)J Sent: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Suzanne Peskin -------~ (b~)-(= Sent: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Sent: To : Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Sent: Tuesday, February 18, 2020 8:04 AM To : Fauci, Anthony (NIH/NIAID) [E) Subject : (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Sent: To: Subject : Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To : Subject : Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Sent : Tuesday, February 18, 2020 4:40 AM To : Fauci, Anthony (NIH/NIAID) [E) Subject : Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) <@nbcuni.com> Sent: Tuesday, February 18, 2020 12:26 AM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com> ; Varela, Jay (NBCUniversal) <@nbcuni.com>; Mitchell, Alexander (NBCUniversal) <@nbcuni.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com> ; Metsch, Abigail (NBCUniversal) <@nbcuni.com> Subject : RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Sent: Monday, February 17, 2020 8:19 AM To : Sheeley, Colin (NBCUniversal) <@nbcuni.com > Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal) <@nbcun i.com>; Mitchell, Alexander (NBCUniversal) <@nbcun i.com>; DiCasimirro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcuni.com > Subject : [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) <@nbcuni.com > Sent : Monday, February 17, 2020 3:36 AM To : Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) <@nbcuni.com >; Varela, Jay (NBCUniversal ) <@nbcu ni .com>; Mitchell , Alexander {NBCUniversal) <@nbcuni.com >; DiCasimir ro, Gemma (NBCUniversal) <@nbcuni.com >; Metsch, Abigail (NBCUniversal) <@nbcun i.com > Subjec t : NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) <@turner .com> Sent: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc:Pfeifer, Hazel <@turner .com>; Avramova, Nina (NE) <@turner.com> Subject : CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Sent: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" <@t urn er .co m> Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" <@turne r.com >, Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike <@t urn er .co m> Sent: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 <@t urner .com> Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject : RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike <@tu rn er.co m> Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject : Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike <@tu rn er .com > wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject : Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Se nt: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date : Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From : Angela Moore (b)(6);, Sent : Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject : COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Sent : Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To : bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject : RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty <@manuscriptcentral.com> Sent: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. Additional information about disclosure of financial and other associations appears below this letter. Please bear in mind that your editoria l represents your (and any coautho r's) personal opinion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal po licy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manuscript can be accepted. Therefore, the enclosed form should be signed by all authors and faxed to (781) 207 -6529. Your editorial is due at the Journa l on Monday, February 17, at the very latest if the deadline imposed by our printing schedule is to be met. ff the editorial is to include a figure, please submit the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. Please provide a title not exceeding 45 characters and a word count for the text; the entire manuscript , including references , should be double-spaced. REFERENCES Cite no more than 10 references , including the article you are writing about. The average collection of 10 references requires about a quarter of a printed page. TABLE OR FIGURE A table or a figure in your edito,ial will require a reduction in the number of words ; because figures and tables vary in size, you may be asked to shorten the text of your editorial during the production process. A quarter-page table roughly equals 250 words , and a half-page table roughly equals 500 words. DISCLOSURES When completing your disclosure fonn , please indicate, in the "Comments" field next to the type of relationship being disclosed, the amount (in U.S. dollars) of any support you have received. Please also indicate how much of NIH-001808 this support has been received over the past 2 years. Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject : FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Se nt: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject : Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From : John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To : AFAUCI @N I AI D. NIH . GOV Sub j ect : Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Se nt: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject : Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Sent : To : Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Sent: To: Subject : Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Sent: To: Subject : Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Townsend, Frances <@l\1AFGRP.COM> Sent: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h <@MAFGRP.COM > Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Sent : To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Fitzgerald, Kate <@umassmed.edu> Se nt: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish <@utoronto.ca> Subject : COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Sent: To: Subject : Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com <@happeningsmag.com > Sent: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Sent: To : Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Jodie Dillman --------~ (b ~)~(6) => Sent: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To : Subject : outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedviginc.com> Se nt: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject : Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko <@hedvigin c.com> wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko <@hedv iginc.com> Se nt: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles <@newshour .org> Se nt : Monday, February 17, 2020 11:51 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven <@....__ 1 Cb _>< ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" <@turner.com > Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From : Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:42 AM To : Figliola, Mike <@turner .com> Subject : RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From : Figliola, Mike <@turne r.com > Se nt : Monday, February 17, 2020 8:40 AM To : Conrad, Patricia (NIH/NIA ID) [E) Subject : RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From : Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:40 AM To : Figliola, Mike <@turne r.com > Subject : Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike <@turner .com > wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike <@tu rner .com> wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Sent: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From:Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike <@turner .com> Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike <@turner .com > Sent: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject : RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Thur sday, January 23, 2020 10:00 AM To : Figliola, Mike <@turner .com > Subject : RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike <@turne r.com > Sent: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject : RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Sent: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike <@turne r.com> Subject:RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From : Figliola, Mike <@turne r.com > Sent : Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike <@turner .com> Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" <@tumer.com > Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject : RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To : Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Se nt : Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Sent : Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject : RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From : Sent : Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From : Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Sent: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject : ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---Fr om: Jon LaPook ______ __,(b""' )..,. (= > Sent: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Sent: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B <@providence.org> Sent : Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subj ect : Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Sent : To : Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Sent: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject : one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Sent: To : Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject : NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Sent : Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 <@tovima.gr> Sent: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) <@niaid.nih.gov > Cc: Fauci , Anthony (NTH/NIAID) [E] Subje ct: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From : Fauci, Anthony {NIH/N IAID) [E) Sent : To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject : RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Folkers, Greg (N IH/ NIAID) [E] Sent: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To : Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject : ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Sent: Monday, Apri l 27 , 2020 4:30 PM To : Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject : Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Sent : M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Sent : To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Sent : Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Sent : To: Subject : Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Sent: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Sent : Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Mascola, John (NIH/VRC) [E] CbH > Sent : Tuesday, May 5, 2020 5:0 4 PM To : Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject : FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From : David Montefiori, Ph.D. Sent: Tuesday, May 5, 2020 1:23 PM To : Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Sent : To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Sent: Tuesday, May 5, 2020 3:06 PM To : NIAID OD AM <@niaid.nih.gov> Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com <@leslevcahillroy.com> Sent: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Sent : Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com <@lesleycahillroy.com> Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject : RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com <@lesleycahillroy.com> Sent : Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject : Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From : Les ley Cah ill Roy <@lesle y cah ill roy .com > Subj ect: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com <@lesleycahil lroy .com > wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Konstantin Vulkov <@egoist .bg> Sent: Tuesday, May 5, 2020 3:42 PM To : NIAID NEWS (NIH/NIAID) <@niaid.nih.gov> Cc: NIAID Ocpostoffice (NIH/NIAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Sent: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Sent: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject:AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Sent : (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Sent : (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu <@umbc.edu > Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Sent : Tuesday, May 5, 2020 8:39 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From : Zh uChen Cb)(6)> Subj ect: Re :SARS -CoV-2 Date : May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subj ect: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Sent : To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Sent: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Sen t: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From:Ola Me lhus (b)( Sent: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Sent: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Sent: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject : Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Sent : Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Sent : To : Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Sent: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From : Harris, Kara (NIH/NIAID) [El Sent : Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc:Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Sent : Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Sent : To : Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From:Augustine M. K. Choi Sent: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To : Corey, Larry Subject : FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Dolsten, Mikael (b)(6)> Sent : Monday, May 4, 2020 8:15 AM To : Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis Fro m : Dolsten, Mikael (b)(6)> Sent : Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject : Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Sent: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Sent : Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subje ct : OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From : Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Se nt : Monday, May 4, 2020 6:20 AM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Se nt : Sunday, May 3, 2020 9:54 PM To : OD-OLPA-Leg Contacts <@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From : Yaworske, Jason A. EOP/OMB Sent : Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject : May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Sent : To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Sent: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc:Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Sent: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Sent: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From:Sogaard, Morten Sent: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Sent: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sent: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Sent : To : -----------, (b =~=(6)) ' Cc: Subject : Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Sent: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc:Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date : Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subje ct : FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Sent: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Sent : To : Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Sent : Sunday, May 3, 2020 1:55 PM To : NIAID OD AM <@niaid .nih .gov> Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com <@lesleycahillroy.com> Sent: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com <@lesleycahillroy .com> wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Sent: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject : Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject:2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Sent: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Sent : To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Sent: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Sent : Thursday, April 30, 2020 6:52 PM To : (b)(6)] (b) (6) Subject : Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From : Sent : To : Subject : Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Sent: Friday, May 1, 20 20 3:09 PM To : Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Sent : Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc:----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject:INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Sent : To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Sent: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Sent: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fro m : Paola Dama (b)(6)> Se nt : Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject : White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From : Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject : Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Sent : Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Sent: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Sent: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Sent : Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To : Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject : RE: From: Sent : Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Sent: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Se nt: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subj ect: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Sent: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Sent : Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject : FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From : Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Sent : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Sent : Monday, April 27, 2020 6:09 PM To : Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subje ct: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject : Please review this draft-----------email to Tony--TX (b)(6) To : (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Sent : To : Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Sent: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To : Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Sent: To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Sent: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject:Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Sent: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To : Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Sent: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El <@niaid .nih .gov>; Harper, Jill (NIH/NIAID) [El (b)( > Cc:Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject : RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From : Johnson, Martin S. (NIH/NIAID) [El Sent : Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc:Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From : Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From : Johnson, Martin S. (NIH/NIAID) [El Se nt : Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg <@mail.nih.gov>; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From : Johnson, Martin S. (NIH/NIAID) (E] Sent : Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg <@mail.nih.gov >; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Sent : Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg <@mail.nih .gov >; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From:Johnson, Mart in S. (NIH/NIAID) [El Sent: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Sent : Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg <@mail.nih.gov>; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From:Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc:Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From:Johnson, Martin S. (NIH/NIAID) [El Sent: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg <@mail.nih.gov>; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject:FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From : Johnson, Ma rtin S. (NIH/NIAID) [El Sent : Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg <@mail.nih.gov >; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Sent : To : (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Sent: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Sent: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Sent: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Sent: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To : (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Sent : Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Sent: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From : Sent : To : Subje ct: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Sent: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Sent: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From:Coney, Lillie Sent : Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Sent : To : Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject : FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Sen t: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Sen t : Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Sent : Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject : RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Sent : Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Sent: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Sent : Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From:Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Sent: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc:NIAID OCGR Leg <@mail.nih.gov>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Routh, Jennifer (NIH/ NIAID) [E] (b)( > Se nt : Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Sent: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Sent : To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject : FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Sent : Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject : RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From : Beige!, John (NIH) (E] -------- Sent : Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To : Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subje ct: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date : Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Sent: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date : Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From : Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From : Dani Bolognesi, Ph.D. Se nt : Thursday, April 30, 2020 8:13 PM To : Fauci, Anthony {NIH/NIAID) [E] Subje ct : RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Sent : Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Sent : Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject : FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Sent : Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subjec t : FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From:"Dani Bolognesi, Ph.D." Date : Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject : Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Sent : To: Subject : Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Sent : Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject : FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Sent : Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subje ct: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<@ethnos.gr> Sent: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 Ato: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Sent: Friday, May 1, 2020 4:53 AM To : Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Sent : To : Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject : FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Se nt : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From : Dani Bolognesi, Ph.D.________ Sent : Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From:"Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date : Monday, April 27, 2020 at 2:53 PM To : "Matthias Gromeier, M .D." (bH Subject : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Jere my Farrar _________ Sent: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. <@nas.edu>; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma <@nas .edu>; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny <@nas .edu> (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau <@nas.edu> , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " <@nas.edu> , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " <@cnn.com>, "Amanda.Se aly@c nn.com " <@cnn.com >, "Neel.Kbairzada(a),turner.com " <@turner.com> , Cb)(6) "McGinnis, J.Mic hael" <@nas.edu> , CbH6) >, ''Mun , Jenny" <@nas.edu >, CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Sent : Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. <@nas.edu>; George (b)(6) ____ ; Hannon, Emma <@nas.edu>; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael<@nas.edu>; (b)(6)>; Mun, Jenny <@nas.edu > (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date : Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau <@nas.edu >, George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " <@cnn .com> , "Amanda.Sealy@cnn .com " <@turner.com " <@tumer.com> , (b)(6)"McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenny" <@nas.edu >, (b)(6) Emma" <@nas.edu >, "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. <@nas.edu> Sent: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma <@nas.edu>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. <@nas.edu> '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From : Dzau, Victor J. <@nas.edu> Se nt : Thursday, Apr il 9, 2020 11:01 AM To : Mun, Jenny <@nas.edu >, ------~~ (b)(6) ; 'ben.tinker@cnn .com ' <@cnn.com >; 'Amanda.Sealy@cnn .com' <@cnn.com >; 'Neel . Khairzada@turner.com' <@tumer.com >; (b)(6) 'Tia.Mi ller@turner.com' <@turner.com >; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Sent: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson <@beatthebomb Se nt : Thursday, April 30, 2020 11:26 AM To : Fauci, Anthony (NIH/NIAID) [E) .com> (b)(6)> Cc: Daniel Lahart <@r egis.org> Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson <@beatthebomb .com> Sent : Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] <@niaid .nih.gov > Cc: Daniel Lahart <@regis.org> Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To : (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Sent: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Sent: Tuesday, April 28, 2020 11:19 Atvl To : Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Sent : To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Sent : Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subj ect: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From : Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject : (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Se nt : Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Sent: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff <@svt.se> Sent: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc:NIAID NEWS (NIH/NIAID) <@niaid.nih.gov>; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Sent : To: Cc: Subjec t : result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIAID) [E] (b)(6J> Se nt : Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject : Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From : Sent : To: Cc: Subject : Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Sent : Thursday, April 30, 2020 5:44 AM To : (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject : COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From : Sent : To : Subject : Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Se nt : Wednesday, April 29, 2020 10:21 AM To : Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Se nt: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Sent: To : Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Wednesday, April 29, 2020 5:03 PM To : NIAID OD AM <@niaid .nih.gov> Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen <@brt .org > Sent: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Sent : Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Sent: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Sent: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] <@niaid.nih.gov> Sent: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] <@niaid.nih.gov> Cc: Folkers, Greg (NIH/NIAID) [El <@niaid.nih .gov>; Conrad, Patricia (NIH/NIAID) [El <@nih.gov>; Routh, Jennifer (NIH/NIAID) [El <@nih .gov>; Lane, Cliff (NIH/NIAID) [El <@nih.gov> Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject : RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To : Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Sent: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sent: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc:Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Sent: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Sent: Tuesday, April 28, 2020 9:57 PM To : Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Sent:Tuesday, April 28, 2020 9:21 PM To : Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject:ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Sent : To : Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From:Lane, Cliff (NIH/NIAID) [El _______ Sent: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From:Lane, Cliff (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Sent : To : Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Sent: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Sent: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To : Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Sent: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To : Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Sent: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Sent : To: Subject : Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subj ec t: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject : Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From : Sent : Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Sent : To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedi a.co m> Sent: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From:"Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias <@ikanamedia.com > Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Sent : To: Subject : Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Sent : Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Sent : To : Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Sent : Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Sent: Tuesday, April 28, 2020 7:08 AM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Sent : Tuesday, April 28, 2020 7:04 AM To : Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Monday, April 27, 2020 8:20 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Dat e: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg <@mail.nih.gov>, " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Dat e: April 27, 2020 at 7:57:36 PM EDT To : "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject : Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To : "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject : LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Sent : Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To : Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Sent: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From : Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Sent : Monday, April 27, 2020 6:09 PM To : Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To : "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subje ct : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Sent: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM <@niaid.nih.gov > this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Sent: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM <@niaid.nih.gov > Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Sent: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From : Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Sent : To : Subject : Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Sent: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subje ct: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Sent: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subje ct : Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Sent: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From:"Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date : Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Sent : Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc:Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From : Sent : To : Cc: Subject : Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Sent: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From : Sent : To : Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject : Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From : Sent: Monday , April 27, 2020 3:0 1 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sent: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From:Taylor Taglianetti <@noiaft.org> Sent: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG <@niaid .nih.gov> Cc:NIAID COGCORE<@mail.nih.gov>, NIAID Media Inquir ies <@niaid.nih.gov> Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Sent: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang <@sinobio logical.info> Sent : Monday, April 27, 2020 8:04 AM To : Anderson, Cassandra (NIH/NIDDK) [E) Subjec t : Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia <@la7.it> Sent: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Sent : To : Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Sent: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM <@niaid .ni h.gov> (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Sent : Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From : Miller , Amanda <@paypal.com > Sent : Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay <@edelman.com > Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Sent : To : Subjec t : (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Sent: Monday, April 27, 2020 10:05 AM To : Fauci, Anthony {NIH/NIAID) [E) -----Subjec t: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! Fr om : "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: Upd ate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de > Se nt: Wednesday, Apr il 22, 2020 9:41 AM To : Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc:'-:-""'."""".~-:----::== Subje ct: Update: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf <@syntacoll.de> Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Sent : Wednesday, Apr il 8, 2020 2:49 AM To : Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf <@syntacoll.de> -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Sent : Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Sent : Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.<@nas.edu>; George (b)(6) ; Hannon, Emma <@nas.edu>; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael <@nas.edu>; (b)(6) Mun, Jenny <@nas.edu>; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau <@nas.edu >, Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" <@nas.edu> , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" <@cnn.com>, ------------- (b) (6) "Amanda. Sealy@cnn .com " <@turne r.com " <@turner.com >, (b)(6) "McGinnis, J.Mic hael" <@nas.edu > , (b)(6)"Mun , Jenn y" <@nas.edu>, CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Sent: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.<@nas.edu>; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma <@nas.edu>; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael<@nas.edu>; (b)(6)> ; Mun, Jenny <@nas.edu>; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau <@nas.edu >, George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" <@nas.edu >, "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " <@cnn.com >, "Amanda.Sealy@cnn.com " <@turner.com " <@turner.com > , (b)( 6) "McGinni s, J.Mi chael" <@nas.edu >, ---------------- CbH6) >, "Mun, Jenny" <@nas.edu>, (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.<@nas.edu> Sent: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc:Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a <@nas.edu >; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael<@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. <@nas.edu> Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.<@nas.edu> Sent: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' <@cnn.com >; ---------'Amanda.Sealy@cnn.com ' <@cnn.com >; 'Neel. Khairzada@turner .com' <@turner.com >; 'Tia.Miller@turner .com' <@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny sent: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Sent: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie <@ncdps.gov> Sent: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Sent : To : (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject : RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Sent : Sunday, May 3, 2020 7:37 AM To : Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To : "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subj ect : Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Sent : Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From : Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To : Subject : Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Sent: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date : Apr il 30, 2020 at 5:46 :27 PM EDT To : Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Sent: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Sent : Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject : RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Sent : Monday , April 27, 2020 9:04 AM To : Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Se nt : Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie <@fda.hhs.gov> Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards from: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From : Fauci, Anthony {NIH/N IAID) [E) Sent : To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject : RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Folkers, Greg (N IH/ NIAID) [E] Sent: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To : Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM <@niaid.n ih.gov> Subject : ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Sent: Monday, Apri l 27 , 2020 4:30 PM To : Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject : Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Sent : M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Sent : Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Sent: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From : Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From : Lane, Cliff (NIH/NIAID) [El Se nt : Sunday, May 3, 2020 1:22 PM To : Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Sent: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Sent: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Sent : Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Sent : To : Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subje ct: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Sent : Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subje ct: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Sent : Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subje ct: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From : Kadlec, Robert (OS/ASPR/10) (b)(6) Sent : Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subje ct: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Sent : To : Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Sent : Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) <@mail.nih.gov> Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig Fro m : Brennan, Patrick (OS/ASPA) (b)(6)> Sent : Wednesday, April 29, 2020 10:33 AM To : Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject : For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Sent: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Sent: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Sent: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Sent: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To : Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From:Secretary ARP (b)(6)> Sent : Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Sent : To : (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Sent: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Sent : Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From : Sent : To: Cc: Bee: Subject : Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From : Collins, Francis (NIH/OD) [El Se nt : Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Sent : Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Sent: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Sent: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Sent : To: Cc: Subjec t : Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Se nt : Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject : FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From : Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo <@lastampa.it> Sent: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subjec t : Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat <@hivr4p.org> Se nt : Thursday, April 23, 2020 11:23 AM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From : HIVR4P- Secretariat Sen t : 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject : HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From : Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Se nt : Thursd ay, Apr il 23, 2020 5:02 PM To : Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Sent: Tuesday , April 21, 2020 11:18_ A _M ____ To : Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Sent: Sunday . April 19, 2020 5:04 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Sent: Sunday , April 5, 2020 9:23 PM To : Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Sent: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE<@mail.nih.gov>; NIAID OD AM <@niaid.nih .gov> Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Sent: Thursday, April 23, 2020 8:31 PM To : Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Sent: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier <@ourpubl icservice.org> Sent: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc:Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies <@ourpublicserv ice.org> Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To : Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject : FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Sent : FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. <@nas.edu> Se nt : Thursday, Apr il 23, 2020 1:49 PM To : Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma <@nas .edu>; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' <@cnn .com>; 'Amanda.Sealy@cnn.com' <@t urner .com' <@turner .com> ; (b) ( >; McGinni s, J. Mic hael <@nas.edu>; (b)( (b)(6) ; Mu n, Jenny <@nas .edu>; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. <@nas.edu> Sent: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma <@nas.edu>; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' <@cnn.com' <@t urne r.com>; 'Tia.M iller@turner .com' <@turner.com >; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Sent : Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Sent : To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Sent : Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc:Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Sent: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Sent: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Sent: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From : David Liu (b)( Se nt: Thursday, April 23, 2020 6:01 PM To : Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Sent : Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc:Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From : Sent : To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Sent: To : Cc: Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Updat e: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To : Fauci, Anthony (NIH/N IAID) [El Subject : FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From : Sent : https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Se nt : Thursday, Apr il 23, 2020 9:04 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Sent : Tuesday, April 21, 2020 11:06 PM Subje ct: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Sent : (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith <@one .org> Date : April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart <@one.org> Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Sent: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Sent: Friday, March 27, 2020 11:55 AM To: NIAID Announcements <@niaid .nih.gov> Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Sent : Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To : Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject : FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Sent : Thursday, April 23, 2020 1:05 PM To : Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman<@sanaria.com> Sent : Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Sent: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Sent: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Sent : Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Sent: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject : Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Sent : To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Sent: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc:Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Se nt: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject : Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Sent : Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject : RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From : Pardis Sabeti (b)(6 )> Sent : Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject : Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Sent: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden <@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Sent : (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject : Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C <@who .int> , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC <@who.int> , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Sent : Thursday, April 23, 2020 10:51 AM To: SHOC <@who.int>; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC<@who .int>; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From : Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( sent: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Sent : To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i <@fortaleza.pr.gov> Sent: Wednesday, April 22, 2020 5:24 PM To : Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan <@prfaa.pr .gov>; Juan L. Negron <@fortaleza.pr.gov>; Antonio L. Pabon Batlle <@forta leza.pr.gov> Subject : letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Sent : To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From:Alice Park <@time.com> Sent: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov>;Conrad, Patricia {NIH/NIAID) [El <@niaid.nih.gov> Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Sent : To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Sent: To: Cc: Subject : Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From : Billet, Courtn ey (NIH/NIAID) [E) Sent : Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams <@caa.com> Se nt: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman <@caa.com> ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date : Tuesday, Apr il 21, 2020 at 4:41 PM --------- To : Judee Williams <@caa.com> Cc: Christine Lancman <@caa.com>, (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject : RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams <@caa.com> Sent : Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc:Christine Lancman <@caa.com > Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recip ient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexual harassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Sent : Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject : FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Sen t: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg {NIH/NIAID) [E] (b)( > Sent : Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Sent : Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject : FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Sent : Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Re: For your attent ion (b)(6) (b) (5) From:Anthony Fauc i Cb)<> Date : Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Sent : Tuesday, April 21, 2020 7:28 PM To : Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl <@fnih.org> Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From:Dzau, Victor J. <@nas.edu> Sent : Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan <@nas.edu> Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Sent : To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From : Gary Noble (b)(6) Sent : Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject : Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Sent : To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha <@calhacks.io> Sent: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Sent: Tuesday, April 21, 2020 11:31 AM To : Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Sent: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc:Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Sent : Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Sent: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject : FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Sent : Tuesday, April 21, 2020 3:01 PM Subject : STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Sent: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Sent: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent: Tuesday, April 21, 2020 4:43 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams <@caa.com> Cc: Christine Lancman <@caa.com >; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams <@caa.com> Sent: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman <@caa .com> Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From : Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Conrad , Patricia (NIH/NIAID) [E) Se nt : Tuesday, April 21, 2020 4:41 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Dat e: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subje ct : Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date : April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject : Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date : T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From : COVID19 Treatment Guidelines <@nih.gov > Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali <@turner.com > Sent : Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines <@nih.gov > Cc: Cohen, Elizabeth <@turner.com >; Fine, Amanda (NIH/OD) [E] (b)( > Subjec t : urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject : FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Sent : Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From : Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim <@global -infra.com> Sen t: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Sent: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject : Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Sent: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Sent: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Sent: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Sent: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen <@rockfound .org> Sent: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] <@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From : Sent: To : Subject : Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) Sent: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From : Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Se nt : Monday, April 20, 2020 7:55 AM To : Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject : Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Sent : Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From : Sent : To : Subject : Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Sent : Sunday, April 19, 2020 6:28 PM To : Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield <@uw.edu > Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld <@uw.edu > Date : Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Sent : To: Subject : Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Sent : Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield <@uw.edu> Subject : FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From : Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Sent : To: Subject : Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Se nt : Sunday, April 19, 2020 9:08 PM To : Collins, Francis {NIH/OD) [E] Cc : M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Sent: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc:Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subjec t: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Sent : To: Cc: Subjec t : Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz <@w ashingtontimes.com > wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Sent : Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To : Cc: Subjec t : Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Sent : Sunday, April 19, 2020 7:06 PM To : Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Sent : Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.<@nas.edu> Sent : Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny <@nas.edu > Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Sent : To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Sent : Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject : Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Sent: To: Subject : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From : Jake Tapper (b)(6) Sent: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subje ct: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) Update: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Sent: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Sent: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Sent: To: Cc: Subjec t : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Sent: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject : You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. <@duke.edu> Sent : Thursday, Apr il 16, 2020 12:39 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Billet, Courtney (NIH/NIAID) [E) (b)(6) Se nt : Thursday, Apr il 16, 2020 1:45 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Sent : To: Subject : Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: Fr om : "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To : SHOC (b)(6) , Office of the Director-General <@who.int> , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s <@resolvetosave lives.org>, "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC <@who.int>, "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Sent: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Sen t : Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject : High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To : Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subje ct: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From:Shapiro, Neil (NIH/OD) (El (b)(6)> Sent: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Sent : To : Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Sent: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Sent : Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Sent : Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Sent: Sunday, April 26, 2020 8 :37 AM To : Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Sent : Saturday, Apr il 25, 2020 5:59 PM To : Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Sent : Saturday, Apr il 25, 2020 5:50 PM To : Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Sent : Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subje ct: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Sent: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc:Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine <@manuscriptcentral.com > Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" <@niaid.nih.gov > Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " <@nejm.org > Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From:Adrian Hill Sent: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To : Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Sent : To : Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Sent: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc:Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Sent: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To : Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From:Yewdell, Jon (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Sent: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Sent: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Se nt: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date : Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subj e ct : Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Sent: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: Update: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf <@syntacoll.de> Sent: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf <@syntacoll.de> Subject: Update : Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf <@syntacoll.de> Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf <@syntacoll.de > Sent: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf <@syntacoll.de> Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From:Xizhong, Cui (NIH/CC/CCM D) [E] Sent: Sunday, April 26, 2020 8:36 PM To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Sent : Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM <@n iaid.nih .gov> Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. Fro m : Kristina Horton <@keystonesymposia.org> Sent : Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subjec t: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Sent : To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Sent: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc:Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject : FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith <@one.org> Sent: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart <@one.o rg> Subje ct : Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy <@bclplaw .com> Sent: Thursday, April 23, 2020 10 :26 AM To : Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Sent : To : Cc: Subjec t : Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Gayle Smith <@one.org> Sent : Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart <@one .org> Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Se nt: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc:"Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Sent: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe <@washpost.com> Sent : Friday, April 24, 2020 12:58 PM To : Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent : Friday, April 24, 2020 3:04 PM To : NIAID COGCORE<@mail.nih.gov> Cc: NIAID OD AM <@niaid.nih.gov> Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Sent : To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton <@keyston esymposia .org> Sent: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Sent: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Sent: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Sent: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Sent : To: Subject : Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Sent: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Sent: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Sent : To : Subject : Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From : Joh n Lauerman 1 8 : 46: 1 6 To : Cc : (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To : John Cc : (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Dat e: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Sent : Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subje ct : spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To : Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Sent: Friday, April 17, 2020 7:51 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From : Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject : RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Sent : Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Se nt : Friday, Apri l 17, 2020 8:03 AM To : Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subj ect : impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviato: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) Oggetto : RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Sent: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviato: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] Oggetto: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviato: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) Oggetto: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Sent:Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject:all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Sent : To : Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Sent: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Sent: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Sent: Tuesday, April 21, 2020 3:46 PM To : Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Sent : Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) <@service.gov deli very.com > Sent : Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Sent: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Sent: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc:Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Sent: To: Subject : Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From : Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject : FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Sent : Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject : Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Sent : To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Sent: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subje ct : Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From : Sent: To : Subject : Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Hahn, Stephen (b)(6):> Se nt : Tuesday, April 21, 2020 3:23 PM To : Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subj ect: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date : Apr il 20, 2020 at 6:26 :14 PM EDT To : Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To : Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subje ct: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Sent: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc:Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To : Hahn, Stephen (b)(6) (b)(6) Cc : Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Sent : Saturd ay, Apr il 18, 2020 3:25 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To : Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject : RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Hahn, Stephen (b)( > Sent : Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject : Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc:Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Sent: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To : Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Sent : Monday, April 20, 2020 10:07 PM To : Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From:Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Sent: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Sent : To : Subject : Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg (NIH/NIAID) [El (b)(6)> Sent : Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM <@ni aid .nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Sent : Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM <@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] <@niaid.nih.gov> Sent : Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]<@niaid.nih .gov> Cc: Stover, Kathy (NIH/NIAID) [E] <@nih .gov>; Routh, Jennifer (NIH/NIAID) [E] <@nih.gov > Subject : RE:ask to highlight the incredible work of key federal worke rs (b)(5) From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Monday, April 20, 2020 4:40 PM To: NIAID OD AM <@niaid.nih.gov> Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject : FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From : Boyse, Natalie (OS/ASPA) (b)(6)> Sent: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject : FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Sent: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Sent: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Sent: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Sent: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc:Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Sent: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Sent: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc:Conrad, Patric ia {NIH/NIAID) [E] ---------Subject : RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Sent : Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject : FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subje ct: RE: Pursuant to My Email on Friday Sent: To: OK. Let us discuss tomorrow. (b)( > From : Mascola, John (NIH/VRC) [E] Sent: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc:Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Sent: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc:Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Sent : Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc:Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Sent: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc:Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Sent : Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To : Cc: Subjec t : Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) MEDCOM (USA) Se nt : Tu esday, April 21, 2020 9:58 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Sent : Tuesday, April 21, 2020 12:49 PM Cb_H_6) To : (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subjec t: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Se nt : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Se nt: Tuesday, April 14, 2020 9:13 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From : (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From : Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From : (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Sent : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Sent: To: Subje ct: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Benoit Ponton <@cpa -qc.ca> Sent: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp CC: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Sent: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Se nt : Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Sent : Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc:Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Sent: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Sent : Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Sent: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Sent: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Sent : To : Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject : RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Sent : Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From : Sent : To: ------- Robert (OS/ASPR/10) Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/N IAID) [E] (b)(6) Sent : Saturday, Apr il 18, 2020 1:54 PM Subject : Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Sent : (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Sent : (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner <@jamanetwork.org > Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa <@jamanetwork.org > Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner <@jamanetwork.org> Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To : Howard Bauchn e r <@jaman etwork.org> Subject : Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Sent : Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To : CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Sent : Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM <@niaid.nih.gov> Subject : Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Sent : (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject : Let us make sure that we discuss this. Begin forwarded message: Fr om : Alice Park <@ti me .com > Date: April 17, 2020 at 2:07 : 17 PM EDT To : "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews <@time.com > Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park <@time.com>w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Sent: To: Subject : Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Sent : To : Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana <@bizsecure .us> Sent: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Sent: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Sent : Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To : Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Sent: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Sent: Thursday, April 16, 2020 6:53 PM To : Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff <@whmo.mil> Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Sent: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject : [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To : Subject : You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon <@mail.huji.ac.il> Sent : Thursday, April 16, 2020 8:09 AM To : Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject : Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon <@mail.huji .ac.il> Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon <@mail.huji.ac.il> Sent: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Sent : To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Sent: Monday , Ap ril 13, 2020 2:49 AM To : Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject : Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To : Cc: Subjec t : Thanks, Dan. Best, Tony From: Daniel Bednarik <@neximmune .com> Se nt : Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Sent: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To : Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject : RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From:Schwetz, Tara (NIH/OD) [E) (b)(6)/> Sent: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date : Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date : TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From : Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Sent: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Sent: To : Cc: Subject : Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Sent: Tuesday, April 14, 2020 8:52 PM To : ICDDIR-L@list. nih.gov Cc: List DEPDIR-L <@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To : Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Sent: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Sent: Wednesday, April 15, 2020 7:18 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Sent : To : Subject : Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano <@asmusa.org> Sent : Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To : Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Sent: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc:List DEPDIR-L<@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From:Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " <@list.nih.gov > Cc: List DEPDIR-L <@list.nih.gov >, NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To : My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Sent: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Sent : Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Sent : Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole <@lewis -burke .com> Sent: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby <@lewis-burke.com > Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From : Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Sent: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Sent: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Sent : To : Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Sent: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Sent : Sunday, April 12, 2020 7:20 PM To : Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Sent : Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From:Miller , Darin B. EOP/OVP Sent : Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Sent: Tuesday, Apr il 14, 2020 6:13 PM To : Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subje ct: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Sent: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc:Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Sent : (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" <@nbcuni.com> , Jeremy Schu lman <@schulmanbh.com > Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller <@schulmanbh.com> Sent: Monday, April13, 2020 5:36 PM To : Mollet, Me lissa {NBCUniversal, WRC) Subject : [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Sent : To : Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) <@knowledgeu.com> Sent: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc:Billie Griffin (bgriffin@knowledgeu.com) <@knowledgeu.com>; Katie Dinsmore (kdinsmore@knowledgeu.com) <@knowledgeu.com> Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Sent: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Sent : To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From:Julio Gali (b)(6) Sent: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred <@washpost .com> Sent : Monday, April 13, 2020 2:30 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Sent: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject : RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Sent : Monday, April 13, 2020 12:50 PM ------ --~ To : Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Sent: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subje ct: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To : 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Sent: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From : Conover, Craig_________ Cb _H_6) Se nt : Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached Fro m: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Sent : Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject : [Extern al] RE: UPDATE:COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDATE: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Se nt : Monday, April 6, 2020 5:22 PM To : Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Sent: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From : Kilmarx, Peter (NIH/FIC) [E] Sent : Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject:* ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Sent: Thursday, April 2, 2020 1:29 PM To : 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Sent: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subje ct: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Sent: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subje ct: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Sent : Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subje ct: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Sent: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Sent: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc:A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From : Conover, Craig_________ Cb _> _<_ > sent: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject : Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From : Kilmarx, Peter (NIH/FIC) [E] Sent : Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject : [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to CC: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From : Kilmarx, Peter (NIH/FIC) [E] Sent : Sunday, March 22, 2020 12:35 PM To : Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From : Kilmarx, Peter (NIH/F ie) [El Sent: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Sent: To: Subject : Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Sent: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Sent : Sunday, April 12, 2020 11:31 PM -------, To : Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc:Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Sent: Monday, Apri l 13, 2020 8:12 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Sent: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc:Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject:FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From:WAYNE REYNOLDS Sent: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Sent: To : Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:t Sent: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@goog le.com > Sent: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Se nt : Monday, April 13, 2020 6:07 AM ------~~ -------- To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Sent: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Sent : Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Sent : To : Subject : Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park <@immunemed .co.kr> Sen t: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subject : FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. <@nas.edu> Sent: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny <@nas .edu>; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma <@nas .edu>; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' <@cnn.com' <@t urner.com>; 'Tia.M iller@turner.com' <@turner.com>; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny <@nas.edu> Sent: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' <@cnn.com>; 'Nee l.Khairzada@turner.com' <@turner.com' <@turner.com> Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From : Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Sent: Saturday, March 28, 2020 3:48 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Sent : Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From : Sent : To : Subject: Thanks,John. ------------ From: Holdren, John P. Sent: Wednesday, March 25, 2020 4:27 PM To : Fauci, Anthony {NIH/NIAID) [E] Cc:Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Sent : Wednesday, March 25, 2020 3:57 PM To : Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Sent : Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Sent : Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To : (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Sent: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To : Cc: Subjec t : REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Sent : Monday, March 30, 2020 9:38 PM To : Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Se nt: Monday, March 30, 2020 10:17 PM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date : March 30, 2020 at 1:15:06 PM EDT To : Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Sent : To : Cc: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Sent : Thursday, April 2, 2020 4:04 PM To : Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) F rom : "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From:Susan Corrigan (b)(6);,, sent: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Sent : Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Sent : To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Sent: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Sent: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Sent : Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject:ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney <@topspinconten t.com> wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Sent: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Sent: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From:Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From:Viswanathan Neelakantan Sent: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Sent : To: Subject : ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To : Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Se nt : Sunday, April 12, 2020 8:47 AM To : Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Sent: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Se nt : Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Sent : Thursday, March 26, 2020 12:59 PM To : Barton Haynes, M.D. _________ Subje ct: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Sent: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Sent: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM <@niaid.nih.gov> Cc:Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn <@ap.org Sent: Sunday, April 12, 2020 10 :56 AM To : Fauci, Anthony (NIH/NIAID) [E] ------~= > CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Sent: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Sent: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Sent : Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent: Sunday, April 12, 2020 10:31 AM To : Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From : Sent : To : Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Se nt : Sunday, April 12 , 2020 1 :10 PM To : Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Se nt : Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Sent: Sunday, April 12, 2020 1 :06 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From : Fauci, Anthony (NIH/NIAID) [E] -------Sent : Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subjec t : RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent: Sunday, April 12, 2020 10:31 AM -------~~- To : Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT<@state .co.us> Se nt : Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Sent: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Sent: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen <@wsj .com> Sent : Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc:Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Sent : Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Sent: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Sent : Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Sent : ----------------From : Sunday, April 12, 2020 5 :54 AM [E] To : Fauci, Anthony (NIH/NIAID) Subject : ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Sent : To: Cc: Subjec t : (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Sent : To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From:Gold, Jeffrey P (b)( > Sent : Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subje ct: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date : Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Sent: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject : Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Sent: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Sent : (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Sent : (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias <@ikan amed ia.com>wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Sent: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM <@niaid.nih.gov> Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon <@jsg.utex as.edu> Sent: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Sent : To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall <@editoria lmanag er.com> Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Sent : To: Cc: Subjec t : Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Jack Killen (b)(6) Sent: Tuesday, April 7, 20201 :31 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subje ct : From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : George GAO (b)(6) Sent: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Sent: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject : Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Sent: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From : Maryja ne Walker Subject: Catching up Date : Apri l 6, 2020 at 9:23:13 PM EDT To : CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Sent: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Sent: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From:Crawford, Chase (NIH/NIAID) [El Sent: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From : Fauci, Anthony (NIH/N IAID) [E) Sent: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To : Subject : FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From : Folkers, Greg (NIH/NIAID) [E] Sent : Friday, April 10, 2020 5:30 PM Subject : Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Sent : (b)(6) Subje ct: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent : Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Sent : To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subjec t : RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Del Rio, Ca rlos ______ (b ""')'""" (= Sent: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject : FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Sent: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Sent : (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From:David Bradley <@theatlantic.com> Sent : Friday, April 10, 2020 10:20 AM ------ To : Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Sent : To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From:David Bradley <@theatlantic.com> Sent: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Sent : Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Sent: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Sent : Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Sent : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject : FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From : Corey MD, Larry (b)(6)> Sent : Thursday, April 9, 2020 3:50 PM ------ ~= To : Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject : COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Sent : (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX <@radio-canada.ca> Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" <@niaid .nih.gov>, "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Sent: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From : Sent : To : Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIAID) [E] (b)(6) Sent : Thursday, Apr il 9, 2020 12:33 PM To : NIAID COGCORE<@ma il.nih .gov>; NIAID OD AM <@niaid.nih.gov> Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Sent : To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante <@outlook.it> Sent: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] <@niaid.nih.gov> Cc:Barasch,Kimberly (NIH/NIAID) [C) <@nih.gov>;Conrad, Patricia {NIH/NIAID) [E) <@niaid.nih.gov> Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Sent : (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Sent : (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe <@rc s.it> Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Sent: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC <@who.int> , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) <@resolvetosavelives.org > , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC <@w ho.int> , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Sent : To: Subject : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) <@nia id .nih .gov> Sent : Wed nesday, Apr il 8, 2020 10:18 AM To : NIAID Announcements <@niaid.nih.gov> Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line <@ors.od.nih.gov > Sent : Tuesday, Apr il 7, 2020 6:23 PM To : NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Sent: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Sent: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Bari llas, Carolina (NIH/NIAID) [El Sent : Wednesday, April 8, 2020 12:39 PM To : Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Sent : To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts <@google.com> Sent: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Conrad, Patricia (NIH/N IAID ) (E] Sent: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From : Billet , Courtney (NJH/NTATD) [E] ______ Sent: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Sent: Wednesday, April 8, 2020 8:56 AM To : Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc : NlAlD OCGR NSWB <@mail.nih .gov> Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Sent: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Sent : Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Sent: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To : Subject : Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Se nt: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To : Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Su bje ct : WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Sent: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Sent: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc:Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From:Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject:[EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject : [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Sent: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject : FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From : Shawn O'Nea il Dat e: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subj ect: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Sent : Tuesday, April 7, 2020 9:31 AM To : Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subje ct: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Sent : Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subje ct: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Sent: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From:Chris Joffe <@joffeemergencyservices.com> Sent: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Sent: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Sent: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Sent : Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From : Sent : Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From : Sent: To : Cc : [E] ----~ Subject : Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Bari llas, Carolina (NIH/NIAID) [E] Sent : Tuesday, April 7, 202011 :04 AM To : Fauci, Anthony (NIH/ NIAID) [E] Cc : Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Sent : Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Sent: Friday, April 3, 2020 3 :34 PM To : Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc:Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: <@pnascentral.org> Date : Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To : ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Sent : To: Subject : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Se nt: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date : April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subj ect: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Sent: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To : (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Se nt: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Se nt : Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Sent : Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subjec t : Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Se nt : Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject : Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Sent : Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From:Chen, Huabiao, M.D. Sent: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject : I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Sent: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Sent : Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject : Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Sent: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Sent: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Sent: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To : Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Sent : Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Sent: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Sent: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Sent : Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Se nt : Thursday, March 26, 2020 5:40 PM To : Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Sent : To : Subject : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Sent : Saturday, Apr il 18, 2020 12:33 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To : Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Sent: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Sent : Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, April 15, 2020 10:20 PM To : Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Sent: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Sent: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subje ct : RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Sent: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Sent : Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Sent: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Sent: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Sent: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Sent: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc:Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Sent: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Sent: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Sent: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Sent : (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Sent : To: Subject : Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Sent : To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Sent: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From : Sent : To : Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Sent : Wednesday, April 8, 2020 9:49 AM To : (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Sent: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Sent : To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Sent: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Sent : To: Subject : Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From : Freire, Maria (FNIH) [T] Se nt : Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From : "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To : "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Se nt : Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Sent: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Sent: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Sent : Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject : Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Sent : To : Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Sent : Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc:Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subje ct: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From : Sent: To : Subject : alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From : Kavesh, William (b)( > Sent: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Sent : To : Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Sent: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Sent : To : Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Se nt : Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subjec t: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert <@pennme d icine.upenn.edu > Sent : Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an Update : VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Mark Feinberg Sent : Saturday, Apr il 4, 2020 4:10 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subje ct: Gr eetings and an Update : VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Sent : To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Sent: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Sent : Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Sent: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Sent : To : Cc: Subjec t : M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando <@ma rianneorlando .com> Se nt : Friday, April 3, 2020 6:55 PM -----~= To : Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject : FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Sent: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Sent: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From : Sent : To : Subject : Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From : Jameson, James L Sent : Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subjec t: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subje ct : Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Sent: To: Cc: Subje ct : FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs <@usc.edu> Sent: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Sent: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To : Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Sent: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Sent: Sunday, April 5, 2020 11:37 AM To : Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc:Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From : RIOUX,Amelie Sent: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Sent: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From : RIOUX, Amelie Sent: Tuesday, 31 March 202009:17 To : 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' <@nic.in >; Toomas (b)(6)>; GPMB Secretariat <@who.int >; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subjec t: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Sent : Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' <@nic.in >; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From : SMITH, Ian Michael Sent: Friday, 27 March 2020 19:19 To : (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' <@nic.in >; Toomas Palu GPMB Secretariat <@who.int >; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Sent: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Sent : To: Subject: death Thanks, Teresa. From: Teri M cPeak <@live.ca> Sent: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From:Silver, David (NIH/NCI) [C) Sent: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Sent : To: Subjec t : (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Sent : To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Sent: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: Fro m : Zach Davi s <@thetrek.co > Date : Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From : Fauci,Anthony (NIH/NIAID) [E) Sent : Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subjec t : RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Sen t: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Sent : To : Subjec t : Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Sent : Saturday, Apr il 4, 2020 10:26 AM To : (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject : Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Sent : To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Sent : To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Sent : To : Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Sent: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Sent: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Sent: Thursday, April 2, 2020 9:58 AM To : Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Sent : To : Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Se nt : Thursday, April 2, 2020 6:05 PM To : Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From : Julie Makani <@blood.ac. tz> Sent : Wednesday, April 1, 2020 5:46 PM ------~= To : Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From : Lerner, Andrea (NIH/NIAID) [El Se nt: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject : My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Sent: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From:Balasundaram, David (NIH/CSR) (E] Sent: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc:Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Sent : To: Subjec t : (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Sent: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Sent: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Sent: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" <@w ashpost.co m> Date : Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar <@bobbleheadhall.com> Sent : Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary <@washpost.com> Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Sent: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Sent: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L <@list. nih.gov> Cc:NIH Director's Executive Committee <@mail.n ih.gov> Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " <@list.nih.gov > Cc: NIH Directo r's Executive Committee <@mail.nih .gov > Subje ct : COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Sent: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 <@globalreporter.it > Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To : Subjec t : fyi From: Brendan Taglianetti <@milfo rd.nh.gov> Se nt : Thursday, April 2, 2020 6:34 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Sent : To: Subjec t : (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G <@nytimes.com>wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar <@bobbleheadhall.com> Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To : <@ny times.com> Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From : Sent: To : Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Sent: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To : Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Sent : Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From : Sent : To : (b)(5)- PC Subject : Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Sent: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To : Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Sent: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Sent: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Sent : To : RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subjec t : It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : (b)(6) Sent : Wednesday, April 1, 2020 9:14 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Sent : Tuesday, March 31, 2020 10:43 AM Subje ct: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Sent : Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subjec t : Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: F rom: Karl Simpson Dat e: Apri l 1, 2020 at 5 :46: 14 AM EDT To : "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Sent : To: Subjec t : Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Se nt : Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Sent : To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin <@arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Sent : To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." <@abgenics.in> Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Sent : To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich <@biosan itize.us> Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor <@b iosan itize.us" <@biosani tize.us> Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Sent: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From:Moshe Levi Sent: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Sent: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subjec t : FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From : Sent : RSVPso rry no. From: Pinho, Paulo <@optimumre .com> Sen t: Monday, March 30, 2020 8:18 AM To : Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" <@the-times.co.uk > Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Sent : To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" <@mail.huji. ac.il> Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Sent : To: Subjec t : Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From : T im Boyd (b) (6) ---------=.,...,-= Sent: Sunday. March 29. 2020 8:53 PM To : Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Sent: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona <@canyonranch.com> Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From:James Thacker <@therimunex.com> Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona <@canyonranch.com > Cc: Patricia Maxwell <@canyonranc h.com >, "dgrange @osp reyg lobalsol utions.com" <@ospreyg lobalso luti ons .com > Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Sent : To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: F rom: "mton-es8@ myse neca.ca " <@myseneca .ca> Dat e: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Sent: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie <@empowerme.e nterprises> Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To : Subjec t : fyi From: Pat Brittenden <@blindfish .media> Sent : Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Sent : To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue <@demiurge. technology >wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue <@demiurge.technology > Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject : COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Sent : To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject : Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Sent : To: Subjec t : (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From : Sent : ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To : Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Sent : ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subje ct: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Sent: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From : Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco <@cn io.es> Sen t: Saturday, March 28, 2020 3:20 PM To : Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. De conformidad con lo dispuesto en el Reglamento (UE) 2016/679 relativo a la protecci6n de los datos personales de las personas ffsicas, la informaci6n personal que nos pueda facilitar a traves de este correo electr6nico quedara registrada por la Fundaci6n CNIO con la finalidad de tramitar el objeto del presente correo electr6nico . El tratamiento de sus datos personales se encuentra legitimado por ser necesario para gestionar el objeto del presente mensaje. Estos datos personales no seran comunicados a ningun destinatario salvo a aquellos que usted nos auto rice o asf venga exigido por una ley. Ud. podra NIH-000151 ejercer los derechos de acceso, rectificac i6n , supresi6n, limitaci6n de tratamiento , portabil idad y oposici6n en la siguiente direcci6n : c/Melchor Fernandez Almagro 3, 28029 (Madrid). Podra ponerse en contacto con el Delegado de Protecci6n de Datos en: delegado lopd@cnio.es. Para el caso de que Ud. precise conocer informaci6n adicional sobre el tratamiento de sus datos personales, puede consultar dicha informaci6n adicional en el siguiente enlace dentro de nuestra pagina web: https://www.cnio.es/es/privacidad/index .asp **LEGAL NOTICE**: This email and any attached files may contain protected information for the sole use of its intended recipient or addressee. Anyone other than the intended recipient or addressee is strictly prohibited from distributing , reproducing or transmitting the email and its contents in any way. If you receive this email in error, please notify the sender and delete the message. Pursuant to the provisions of EU Regulation 2016/679 regarding the protection of personal data, any personal information you provide through this emai l will be registered by the CNIO Foundation in order to deal with content of this email. Your personal data must be processed in order to be able to deal with the content and purpose of this message. Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Sent: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc:List DEPDIR-L<@mail.nih.gov>; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Sent : (b)(6) To : Subject : FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Sent : Friday, March 27, 2020 6 :11 PM To: NIAID OD AM <@niaid .nih .gov>; Subject : W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Sent : To: Subjec t : (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Sent : Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Sent : To : Subject : Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From : Billet , Courtney (NIH/NIAID) [E] Se nt : Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From : Billet, Courtney (NIH/NIAID) [E] Sent: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From : Routh, Jennifer (NIH/N IAID) [E) Sent : Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Sent: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Se nt: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subjec t : RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Sent: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc:Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From:Rout h, Jennifer (NIH/NIAID) [E] _______ Sent: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc : -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From:Routh, Jennifer (NIH/NIAID) [E] Sent: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From:Routh , Jennifer (NIH/NIAID) [E] Sent: Tuesday, March 24, 2020 7:48 PM To : O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc:Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From:O'Malley, Devin M. EOP/OVP Sent : Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Se nt : Tuesday, March 24, 2020 7 :34 PM To : Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Sent : Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To : Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Sent : To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it <@libero.it> Sent : Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici Oggetto : Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From:Conrad , Patricia (NIH/NIAID) IE] Sent: Saturday, March 28, 2020 7:28 AM (b)( '> To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From:Janet Tobias <@ikanamedia.com> Date : March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Sent: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Sent : To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Se nt: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject : NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Sent : To : Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Sent: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback <@ncbi.nlm. nih.gov> Sent: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Sent : To: Subjec t : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias <@ikanamedia .com> Sent: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Sent : Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To : Subjec t : Thanks,John! From: Burklow, John (NIH/OD) [E) -------Se nt : Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To : Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject : Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Sent: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe <@frame.media > Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe <@frame.media >wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Sent : To : Subjec t : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Sent : Friday, March 27, 2020 10:28 AM To : Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Sent: To: Cc: Subject : RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Se nt : Friday, March To : Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject : Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Se nt: Friday, March 27, 2020 11:24 AM To : Narasimhan, Sri Devi (ELS-CMA)<@cell.com> Cc: Fauci, Anthony (NIH/N IAID) [E] <@niaid.nih.gov> Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Sent: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Sent: Thursday, March 26, 2020 4:53 PM To : Narasimhan, Sri Devi (ELS-CMA) <@cell.com > Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA)<@cell.com > Sent: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Sent: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Sent : To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Sent: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Sent : To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To : Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent : Thursday, March 26, 2020 9:08 AM To : Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Sent: Wednesday, March 25, 2020 6:3 1 PM To : Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William <@apcoworldwide .com > Sent : Wednesday, March 25, 2020 4:24 PM To : Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subje ct: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Sent: Thursday, Ma rch 26, 2020 5:02 AM To : Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Sent : To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Sent : Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject : Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Sent : To : Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore <@health.ucsd.edu> Sent: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n <@health Subject : Re: George Church interview Date: March 24, 2020 at 12:09:20 PM PDT To: Jon Cohen <@aaas.org> NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen <@aaas.org> wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore <@ucsd.edu> wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Sent : To: Subjec t : Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Sent: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:DELFRAISSYJean-franco is Sent: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Sent: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Sent: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subjec t : RE:wi th love fro m Italy From: Sent : Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Se nt : Wed nesday, March 25, 2020 7:58 AM To : Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From : Jon LaPook ______ __,(b'"" )..,. (6) = Sent: Tuesday, March 24 , 2020 2 :17 PM To : Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subj ec t: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Sen t: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subjec t: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Sent: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Sent : Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Sent : To : Subjec t : From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Se nt : Tuesday, March 24 , 2020 8 :59 PM To : Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Sent : To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Sent : Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From:Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Sent : Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Sent: Monday, March 23, 2020 10:45 PM To : Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able to: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From : Sent : To : Subject : Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : RYAN, Michae l J. (b)(6) Sent : Tuesday, March 24, 2020 10:59 AM To : SHOC<@who .int> ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives <@reso lvetosavelives .org>; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc:SHOC<@who.int>; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Sent : To: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From : Raphael De Montferrand <@rttv .fr> Sent: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject : FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : Folkers, Greg (NIH/NIA ID) [E] (b)(6) Sent : Tuesday, March 24, 2020 10:16 AM To : NIAID OCGR Leg <@n iaid .nih .gov>; NIAID COGCORE<@mail.nih.gov> Subj ect: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Sent: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Sent: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC <@everb ri dge.net > Sent: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Sent: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Sent: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc:Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen <@washpost.com > Sent: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley <@washpost.com > Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Sent : To: Subjec t : (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Sent: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams <@wamu.org > Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" <@niaid.nih .gov> Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Sent: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Sent: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To : "ICDDIR-L@LIST.NIH.GOV " <@LIST.NIH .GOV> Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Sent: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Sent: To : (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Sent: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Sent : To : Subject : Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From : Barry Albertson <@fannocreek .com> Sent : Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Sent: Monday, March23, 2020 9:49 AM To : 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Sent : To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Sent: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To : (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Sent : To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Sent: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Sent : Sunday, Marc h 22, 2020 9:31 PM To : Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Sent : To : Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Sent: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc:NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up to: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up to: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Sent : Saturday , March 21, 20 20 5 :25 PM To : Young, Howard (NIH/NCI) [E]________ Subje ct: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Sent : To : Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Sent: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From : Sent : To : Subject : Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Sent : (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject : Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To : Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner <@jamanetwork.org> Sent: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani <@jamanetwork .org> Cc: Edward Livingston <@jamanetwork .org> Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner <@jamanetwo rk.org>, Tony Fauci 6b , Preeti Malan i <@med.um ich.edu>, Eli Perencevich , Phil Fontanarosa <@jamanetwork.o rg> Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner <@jamanetwo rk.org> Sent: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Sent: To : Subject : ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Se nt : Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Sent : Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject : Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Sent: To : Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Sent: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject : FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Sent : For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Sent : Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject : Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Karen Backman (b)(6) Sent: Monday, March 23, 2020 8:53 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Subj ect : Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Sent : To : Subj ect : At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Sent: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Sent : (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To : David Rubenstein Subjec t: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From : Se nt: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From : Marston, Hilary (NIH/N IAID) (E] (b)(6) Sen t : Sunday, March 22, 2020 7:10 PM To : Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject : Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subj e ct: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From : Jo n LaPook ,.....___ _,(""' b),,.., (6) => Sent : Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Sent: To : Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G <@nytimes.com> Sent: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject : big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Sent : Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject : Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Sent: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To : Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Sent: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Sent: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject : Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject : RE: Dr. Fauci: Senate Draft COVID-19 Supp Sent : (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Sent : Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subj ect : Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Sent: To: Subject : Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To : Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Sent: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Sent: To : Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Sent : Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To : Cc: Subject : ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To : Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject:Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Sent: To: Subject : Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Dat e: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Sent : (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Sent : To : Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From:John Monahan <@georgetown.edu> Sent: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Sent: (b)(6) To : Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Sent: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Sent: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject : Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) <@uidaho .edu> wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Sent : (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To : Subject : Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Sent: To: Subject : (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re <@health.ucsd .edu> wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Sent : (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" <@sriramachandra .edu.in> Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Sent : (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To : Subject : Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna <@ho lycross .bc.ca>wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Sent: Sat, 21 Mar 2020 07 :35:58 -040 0 To : DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Sent: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D <@email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Sent : To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From:Priscilla Kelly <@aaas.org> Sent : Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Sent: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To : Subject : Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Se nt : Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject : FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date : Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Se nt : Friday, March 6, 2020 8:46 PM To : Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject : Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Sent : (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From:Collins, Francis (NIH/OD) [E] (b)(6)> Sent: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Sent: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject : RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Sent : Thursday, March 19, 2020 9:31 PM To : Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc:Tabak, Lawrence (NIH/OD) [E] (b)(6) Subjec t : COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard <@rwjf .org> Sent: Thursday, March 19, 2020 3:59 PM To : Fauci, Anthony (NIH/NIAID) [E] <-----Subject : Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Sent : To: Cc: Subject : - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Sent : Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject : FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Sent : Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier Elemento : Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject : [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Sent: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To : (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From : Cb)(6J.> Sent : Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject : Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Sent: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To : Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject : [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Sent : Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To : "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Sent : Wed nesday, Marc h 18, 2020 5 :09 PM Subject : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Sent : Thu, 19 Mar 2020 08:30:51 -0400 To : Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From : Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To : Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Sent: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To : Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject : FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Se nt : Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Sent: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To : Cc: Subject : Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila <@nyt imes .com > Sent: Wednesday, March 18, 2020 4:10:58 PM To : Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject : Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila <@nytimes .com > Sent: Wednesday, March 18, 2020 3:27 PM To : Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject : Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes .com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Sent: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila <@nytimes.com> Sent: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject : Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila <@nytim es.com > Sent: Wednesday, March 18, 2020 3:27 PM To : Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@nytimes.com > wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen <@b io- signal.com> Sent: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Sent: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila <@nyt imes.com> Sent : Wednesday, March 18, 2020 4:10:58 PM To : Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila <@nyt imes.com > Sent: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila <@ny t imes.com > wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Sent: To : Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Sent: Wednesday, March 18, 2020 8:16 PM ------~= To : Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Sent: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Se nt: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Sent: To : Subject : Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Sent : Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subje ct: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Sent : (b)(6) To : Subject : Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Sent: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Sent: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Sent: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Sent: To: Subject : (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Sent: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Sent: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Sent: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject : FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From:Lane, Cliff (NIH/NIAID) [E) Sent: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Sent: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Sent : To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject : RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Sent : Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject : Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Sent: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject : RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Sent: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Sent: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From:Collins, Francis (NIH/OD ) [E] Sent: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Sent: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject : RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Se nt: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject : Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From : Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Sent : To: Subj ect : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Sent : Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Sent : Wednesday, March 18, 2020 4:01 PM To : Fauci, Anthony (NIH/NIAID) [El Subject : Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : WW (b) (6) Sent: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To : Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject : Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Sent: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Sent: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To : Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From:Alexandra Flemming <@nature .com> Sent: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Sent: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey <@bio.org > Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = <@bio.org> --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Sent : (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias <@ikanamedia.com > Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias <@ikanamedia.com> Sent : Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Sent : To : Subject : Please respond. From : EDWARD EITZEN (b)(6) Se nt: Sunday, March 8, 2020 3:10 PM ~= To : Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject : Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Sent: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject : Please respond for me. -----Original Message ----From: Candace Gunn --------Sent : Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Sent : To : Subject : Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Sent: Saturday, March 7, 2020 5:27 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Sent : Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To : Lerner, Andrea (NIH/NIAID) [El Subject : FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From:Tabak, Lawrence (NIH/OD) [El Se nt: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From:John G. Boland Sent: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject : Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Sent: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subje ct: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From : Pardis Sabeti (b)(6) Se nt : Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject : Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date : Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From:Wi llick, Jason <@wsj.com> Sent : Monday, March 16, 2020 9:44 PM ------------- To : Fauci, Anthony (NIH/NIAID) [E] Subject : Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Sent: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailto: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Sent: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Sent: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Sent : Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Sent : Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Sent: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From:Monticone, Giulia (b)(6)> Sent: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Sent: To : Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Sent : Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Sent: Monday, Ma rch 16, 2020 3:19 PM To : Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE<@n iaid.nih.gov>; NIAID FOG<@niaid .nih .gov> Subject : Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Sent: To: Subject : _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Sent: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Sent: To: Subject: Please respond. From: PEAK (b) (6b Sent: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Sent: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Sent: Mo n, 16 Mar 2020 14:31:15 -0400 To : Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Sent : (b)(6) To : Subject : Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Sent : (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To : Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject : Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<@,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD T o: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Sent: To: Subject : Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Sent: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Sent : (b)(6) To : Subject : Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Sent: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Sent: To: Subject : Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Dat e: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Sent: (b)(6) To : Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Sent: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Sent: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" <@FOXNEWS.COM> Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From : Baier, Bret <@FOXNEWS.COM> Sent : Friday, March 13, 2020 3:30 PM To: Koerber, Ashley <@FOXNEWS.COM>; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject : RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Sent: Friday, March 13, 2020 3:27 PM To : 'Conrad, Patricia (NIH/NIAID) [E]' Cc : Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret <@FOXNEWS.COM> Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley <@FOXNEWS.COM> Sent: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley <@FOXNEWS.COM> Sent: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subje ct: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley <@foxnews.com >wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 <@foxne ws.com >wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From : Koerber, Ashley Se nt: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject : Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Sent: To: Subject : Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject : FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Sent : Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Sent : Sunday, March 15, 2020 10:13 PM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject : ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Se nt: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject : Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Se nt: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subje ct : Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Sent: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From : Bertuzzi, Stefano Sent: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject : Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject : From: David Bardan (b)(6)> Sent: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc:Shriya Palekar <@tytocare .com> Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Sent: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To : "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Sent: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject : Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Sent: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson <@zrgpartners.com> Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Sent: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Sent: To: Subject : Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Sent: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject : Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Sent: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Sent: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson <@robinsonmanagementserv ice.com > wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Sent: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Sent: To: Subject : Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y <@howard.edu> wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Sent: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Sent: To: Subject : Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Sent: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To : Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones <@winning-newsmedia.com> wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Sent: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Sent: To: Subject : (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Sent : Sun, 15 Mar 2020 18:55:37 -0400 To : el Subject : Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Sent : (b)(6) To : Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject : Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Sent : (b)(6) To: Subject : Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Sent: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject : RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Se nt: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Sent: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject : Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Sent: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To : Subject : Please handle. ------------- From: Landrigan, David Sent: Sunday, March 15, 2020 1:44 PM To : Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Sent : To: Subject : This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Se nt : Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject : Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Dat e: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject : Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" <@turne r.com > Dat e: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject : [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Sent : Sun, 15 Mar 2020 13:30:08 -0400 To : Soumya Jayaraj Subject : Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Sent: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Sent: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject : Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Sent : (b)(6) To : Subject : Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Sent: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian <@slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian <@slammiami.com> -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Sent: To: Subject : Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Sent: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject : Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq <@jsgroup.com.kw> wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Sent: To: Subject : (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Sent: To: Subject : Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Dat e: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Sent : To : Subject : Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From:Collins, Francis (NIH/OD) [E] Sent : Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject : Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Sent : To: Subject : Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Se nt: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject : Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From:Ramaswamy,Sriram Sent: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Sent: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Sent: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Sent: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To : Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson <@med.cornell.edu>wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Sent: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 <@columbi a.edu>; kathleen foley (b)(6); Carol Storey-Johnson <@med .corn ell .edu > Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Sent: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject : Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Sent : (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To : Subject : Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To : "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Sent: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Sent : (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Sent: To: Subject : Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Se nt : Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Sent : To : Subject : Thank you! From: Halula, Madelon (NIH/NIAID) [E] Sent : Monday, March 9, 2020 10:10 AM To : Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject : Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Sent: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Sent : (b)(6) To : Subject : Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Sent: To: Subject : (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From:Celia Lewis (b)(6)> sent: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Sent: To: Subject : Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Sent: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Sent: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Sent: To: Subject : William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Sent : Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Sent : To : Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Sent : Friday, March 13, 2020 8:23 PM To : Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Sent: To: Subject : Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----from : Alecia Siuta :.:-------(b ~)-(6) ~ Sent: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Sent: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To : Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Lynda Hayashi Sent : Thursd ay, March 12, 202010 :17 PM To : Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject : dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Sent : (b)(6) To : Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject : Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Sent : (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To : NIAID Public Inquir ies Subject : Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Dat e: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject : thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Sent: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To : Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Sent: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Sent : (b)(6) To : Subject : Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To : "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Sent: (b)(6) To : Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Sent: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To : Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Sent : Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subjec t: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From : Marston, Hilary (Nll-1/NIAID) [El Sent: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Sent : Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject : Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To : Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject : RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Sent : Tuesday, Ma rch 10, 2020 9 :54 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Sent: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Sent: Saturday, March 7, 2020 3:18 PM To : Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Sent : To: Subject : Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Sent: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject : Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Sent : Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject : FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Sent: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject : Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Sent: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From:Robert Danoff (b)(6) Sent: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From : Rose Marie Codling <@literacymatters .education> Sent : Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From : Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From : Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Se nt: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject : FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From : Collins, Francis (NIH/OD) (E] Se nt : Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject : RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Sent: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject : ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject : Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Se nt: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject : FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley <@researchamerica .org > Date : Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney <@resea rchamerica .org> Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From:Robert Tober (b) (6)> Sent: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Sent: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From:Jason Ressler (b)( Sent: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Sent : To: ---- ------ ,a-s-r:= Subject : (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Se nt : Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject : Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Sent : (b)(6) To : Subject : Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Sent : To: Cc: Subje ct: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah <@cbsnews.com> Sent: Thursday, March 12, 2020 9:12 AM To : Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] <@cbsnews.com> Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah <@cbsnews .com> Sent: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam <@cbsnews .com > Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From:Arthur Ammann Sent: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Sent: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Sent: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To : Subject : Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Sent: To: Subject : (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Sent: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Sent: To: Subject : Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From : Whit Clark ,,,_..-----= (b,.,. )""' (6) =Sent: Wednesday, March 11, 2020 7:39 AJ\'1 To : Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Sent: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Sent: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Sent: To: Subject : Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Dat e: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Sent: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Sent: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Sent : To: Cc: Subje ct: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Sent: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu <@stanford.edu> Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" <@stanford.edu >, Amanda Chase <@sta nford.edu > Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Sent : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To : Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:David Knipe <@hms.harvard.edu> Sent: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Sent : Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Tue, 10 Mar 2020 17:46:08 +0000 To : Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Sent: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:1iiJ ~ (b)(6)> Sent: Tuesday, March 10, 2020 1:46 AM To : Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject : asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject : FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Se nt: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Sent : To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Sent: To: Subject : Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----from : Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Sent: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Sent : Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To : Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Sent: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To : Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Sent: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas<@bernstein.com > Date : Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From : Greg OKeeffe ------------ (b)(6) Sent: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas <@be rnste in.com > Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Sent : To : (b)(6) Subj ect : At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From : CMS (b)(6) Se nt : Sunday, March 8, 2020 9:02 PM To : (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subj ect : Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: Fro m: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Dat e: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc:"Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject : Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Sent : To : Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From:Rita DiCasagrande Olsen Sent: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To : Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Se nt: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject : RE: COVID-19 From: Sent: To : Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Collins, Francis(NIH/OD) [E] Sent : Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject : RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Sent: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject:COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject : Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Sent: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Sent: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Sent : To : Subject : mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Sent : Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject : NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Sent : (b)(6) To : Subject : Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Sent: To: Subject : (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Sent: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To : Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas <@economist.com> Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas <@econ omist.com >wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Sent : (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Sent: To: Subject : Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date : March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Sent: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To:--------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From : Radostaw Sierpinski Date : March 9, 2020 at 6:42:08 AM EDT To : "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject : CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Sent : To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From:Greg Reilly <@theceoforumgroup .com> Sent: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Sent : To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Sent : Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject : FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date : Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject : Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Sent: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To : Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller <@cbc .ca> Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Sent: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject : Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Dat e: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Sent : (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Sent: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject : Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Sent: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Sent : To : Subject : Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke <@americamedia.org > Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Se nt: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Sent: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Sent : Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From:Alex Wolf, Esq. (212)717-2 510 <@wolf lawyer.com> Sent : Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject : Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Sent: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Sent : To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Sent: Monday , March 9, 2020 5:29 AM To : Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From : William Chin ________ (b_)~( = > Sent: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To : Subject : Thanks, Glenda! From: Glenda Gray <@mrc .ac.za> Se nt: Tuesday, March 3, 2020 9:37 AM _________ ..... To : Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subj ect : FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject : 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Sent : To: Subject : Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Sent : Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Sent : To : ---- Subject : Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Sent : Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject : FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date : Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject : RE:Thanks so much Sent: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Sent: Sunday . March 8. 2020 9:48 PM______ To : Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Sent: To : Subject : From: Clayton Conger Se nt : Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Se nt: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject : Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From : Hellmich, Helen Se nt: Sunday, March 8, 2020 5:52 PM To : Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject : can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Sent: Sunday, March 8, 2020 7:02 PM To : Fauci, Anthony {NIH/ NIAID) [E] Subje ct: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From : William Schiesser (b)( Sent : Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject : COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To : Subject : RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Sent : Sunday, Marc h 8, 2020 8:12 PM To : Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject : Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Sent : To: Subject : FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin <@hdltherapeutics.com> Sent : Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject : URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Dat e: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert <@steinmancommunications.com> Se nt : Sunday , March 8, 2020 7:59 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject : Please handle. From: Barb E Se nt: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject : RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From : Austin, Christopher (NIH/NCATS) [E] Sent : Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject : RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From : Collins, Francis (NIH/OD) [E]______ Sent : Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject : RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From : Collins, Francis (NIH/OD) [E] Sen t: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject : ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From : Sent : To : Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From : Greg Simon (b) ( > Se nt : Friday, March 6, 2020 7:22 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject : Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Dat e : Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Sent : To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject : FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject : FYI ________ ________ -------=-:--:= (b)__, (6)> From:IPJ::J~lli-1Sent : Sunday, March 8, 2020 9:58 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Sent : To : Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Se nt: Sunday, March 8, 2020 2:54 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From:Anthony Fauci (b)(6) Date : Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject : RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Sent : Sunday, March 8, 2020 11:17 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject : We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Sent: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To : Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Sent: Saturday, March 7, 2020 3:40 PM To : Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Sent: Sunday, March 8, 2020 10:13 AM To : Fauci, Anthony {NIH/NIAID) [E] Subje ct: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Sent : Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To : CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Sent: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Sent: Sun, 8 Mar 2020 09:59 :21 -0400 To : Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur <@bio.or g> Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur <@bio .org> Cc: Jenni fe r Alton <@pathwaypolicy .com>, Ellen Carlin (bH6) >, Amy Walker <@bio.org>, Grego1yFrank ---------<@bio.org> Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Sent: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Sent: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To : Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Sent : (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Sent: Saturday, March 7, 2020 4:09 PM To : Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Sent: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Sent : (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To : Cassetti, Cristina (NIH/NIAID) [E] Subject : Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Sent: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Sent: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To : Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone <@scripps.edu> Sent: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Sent : Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From:Liz Cheney CbH6)> Sent: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject : Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Sent: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Sent : Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Sent : To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada <@elconfidencial.com> Sent : Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Sent : Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Sent: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Sent: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah <@bmc .org> Sent: Saturday, March 7, 2020 5:19 PM To : Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc:Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From : Fauci, Anthony (NIH/NIAID) [E) Sent: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Sent: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc:secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject:One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" <@scientekpower.com> To: (b)(6) Reply-To: <@scientekpower .com> Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Sent : Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To : (b) (6)' Cc: RE:NSCinquiry on treatment study Subjec t: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Sen t : Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject : NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject : We are pursu ing th is idea. From: Gregory Klomp Se nt: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject : COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Sent: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To : Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Sent : To: Cc: -------- Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Sent : Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Sent: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Sent: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Sent: To: Subject: Please have someone respond. From: Leonard Trudell Sent: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To : Subject : Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Sent: Saturday, March 7, 2020 11:56 AM To : Fauci, Anthony (NIH/NIAID) [E] Subject : Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Sent: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Sent: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Sent: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To : Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Sent : Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Sent: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Sent : (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Sent: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From:Elizabeth Stevens Sent : Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Sent: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To : FW: Subject : ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Se nt : Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Sent: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From:Ann Job (b)(6)> Sent : Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject : 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Sent: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Sent: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Sent: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From:Anderson, Jennifer (NIH/NIAID) [E] Sent: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From : Lipkin, Ian W. _________ Cb _> _<_, Sent: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From : L ipkin, Ian W. _________ Cb _)_(_. 6l> Sent: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Sent : Friday, March 6, 2020 6:18 PM Subject : JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Sent: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Sent: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Sent: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Sent: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Sent : Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Se nt: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject : RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Sent: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Sent: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject : FW: Developing Immunity to SARS-CoV-2and lvlg From: Sent : Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm <@kammconsultinginc.com> Sent : Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To : Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From : Corey MD, Larry Sent: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Se nt : Thursday, March 5, 2020 11:19 PM Subject : NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) <@msnbc .com> Sent : Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject : Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Sent : Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To : Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Sent : Friday, March 6, 2020 3:46 AM -------=:-:-=, To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Sent: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From:Corey MD, Larry Sent: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Sent: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Sent : Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject : FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Sent : Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject : SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject : FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To : fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Se nt: Wednesday, Marc h 4, 2020 4:27 PM Subject : medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From:James Krellensteih sent: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From : Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject : Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From : Pavletic, Steven (NIH/NCI) [E) (b)(6)> Se nt: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From : Brian Betts (b)(6)> Sent : Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject : Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Sent : To: Subject : Let us discuss. From: Stephen Morrison <@csis .org> Se nt : Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman <@csis.org> Subject : Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison <@cs is.org > wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Sent : F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To : Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Sent: Thursday, March 5, 2020 7:49 AM To : Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From : Phillips , Kyra <@abc.com> Sent: Thursday, March 5, 2020 9:30 AM To : Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra <@a bc.com > > Sent: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Sent: To: Subject : (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Sent: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Hurst, Natalie R. EOP/OVP (b)(6) Sent: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Sent: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Sent: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To : Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Sent : For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Sent: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Sent : To : Cc: (NIH/NIAID) [E] Subject : Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To : Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject : T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date : Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Sent: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To : Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Sent: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc:Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date : February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Sent: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From : Carte r Mecher NIH-001470 Sent : Friday, February 21, 2020 6:52 PM To : Richard Hatchett ; Dr. Eva K l ee Cc : Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Sent: Friday , February 21, 2020 1:59 PM To : Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From : Carter Mecher Sen t: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject : RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From : Carter Meche r Se nt : Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Sent : Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Sent: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From : Carter Mecher Sent : Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Sent: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From : Carte r M eche r Sent : Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Sent : Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subjec t: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Sent : Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Sen t : Thursday, February 20, 2020 11:00 AM To : Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Sent: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Sent: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc : Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Sent: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Sent: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From : Carter Mecher Sent : Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Sent : Wednesday, February 19, 2020 4:45 PM Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From : (b)( Sent : Wednesday, February 19, 2020 2:36 PM To : Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From : Carter Mecher Sent : Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Sent : Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Sent: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Sent: Wednesday, February 19, 2020 6:06 AM To : Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Sent: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc:Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject : RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Sent: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Sent: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Sent: Tuesday , February 18, 2020 1:06 PM To : Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Sent: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Sent: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Sent: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject : RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Sent: Tuesday, Februaiy 18, 2020 10:45 AM To : Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From:Carter Mec her (b)(6) NIH-001527 Sent: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Sent: Tues day, Feb ruary 18, 2020 10: 15 AM To : Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Sent: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Sent: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Sent: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc:C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Sent: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Sent: Monday, February 17, 2020 4:51 PM To : Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Sent: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Sent: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Sent: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Sent: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Sent: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From : Cart er Mecher Sent: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Sent: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Sent: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Sent: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Sent: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Sent: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Sent: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Sent: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject : FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date : Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To : "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc:"Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subje ct: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject : Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Se nt : Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject : Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Sent: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subje ct : Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From : "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date : February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From : Grigsby, Garrett (HHS/OS/OGA) (b)(6) Sent : Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject : Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date : February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Se nt: Friday, Februa ry 21, 2020 5:53 AM To : Fauci, Anthony (NIH/N IAID) [E] Subj ect : Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Thu, 20 Feb 2020 21:26:05 +0000 To : Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From : Kadlec, Robert (OS/ASPR/10) < (b)( > Sent : Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject : HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject : RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Sent : HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Se nt: Wednesday, February 19, 2020 10:54 PM To : Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject : RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Sent : Wednesday, February 19, 2020 10 :06 PM To : Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject : RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Sent: Wed nesday, February 19, 2020 10 :02 PM To : Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From : Sent : To : Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From : Billet, Courtney (NIH/NIAID) [E] Sent : Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subj ect : Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From : "Hall, Bill (HHS/ASPA)" (b)(6)> Dat e: Tuesday, February 18, 2020 at 4:52:06 PM Subj ect : FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List <@LISTSERV .CDC.GOV> On Beha lf Of Media@cdc .gov (CDC) Se nt : Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subje ct : CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Sent : To : Bee: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Sent : Monday, February 17, 2020 2:56 PM To : Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date : February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Sent: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject : RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Sent : Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen <@was hpost .com> Se nt: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject : WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To : Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject : RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Sent : Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Sent : Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject : Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Sent : Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject : FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Sent : Saturda y, February 22, 2020 10:52 AM Subj ect : Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Se nt : Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject : COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject : RE: Infectious d isease advice for NSO Asia tour Sent : Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Se nt : Friday, February 21, 2020 6:31 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject : Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Se nt: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc:Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Sent: Friday, February 21, 2020 5:21 AM To : Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F.<@Kennedy-Center .org> Sent: Thursday, February 20, 2020 5:59 PM To : Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary <@Kennedy-Center .org> Subject : Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Sent: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To : Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul <@thaiembdc.org> Sent: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc:Chuliepote lsarankura Na Ayudhaya <@thaiembdc .org> Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Sent : To : Subject : Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Redfield, Robert R. (CDC/OD) Sent : Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject : Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From : Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Sent: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject : Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Sent: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Sent: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject : Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To : Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject : RE: COVID-19 messaging From: Sent : (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Sen t : Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject : Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date : Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject : RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Sent : Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject : COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Sent : To: Subject : Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Sent: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject : FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject : Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From : "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From : Schmitt, James(NIH/OD/ORS) [El Sent: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc:Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Sent : Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc : Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject : COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To : Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Sent: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc : Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From:Gary K. Schoolnik (b)(6)> Sent: Friday, February 14, 2020 6:27 PM -----~~ To : Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject : Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Sent: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To : Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz <@vox.com>wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Sent: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Sent: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM <@niaid.nih.gov> Subject : FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Sent: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject : Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Clayton, Janine (NIH/OD) [El Sent : Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From : Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Sent: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject : 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Sent : To: Subj ect : (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From : Steven Lehrer Sent : Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject : ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Sent : Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject : for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Sent : Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject : (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Sent: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Sent : Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject : _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Sent : To : Subj ect : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Sent : Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject : RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Sent: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From : Fried, Linda P . (b)(6) Sent : Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject : Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To : Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Sent : Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject : A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject : FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Se nt: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM <@niaid.nih .gov> Subject : FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From : Sent : To : Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling <@thedocumentarygroup .com> Se nt : Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) <@niaid.nih.gov>; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE DATE: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Sent: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From:Calio, Nicholas <@airlines.org> Sent: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To : Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Sent: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To : Fauci, Anthony (NIH/NIAID) [El --------- Subject : FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Sent : Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject : Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Sent: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Sent: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Sent: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From : Banner, Jon {PEP} (b)(6)> Se nt: Tuesday, February 11, 2020 9:44 PM To : (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject : Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Sent : To : Subject : Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Sent : Thursday, February 13, 2020 12:45 PM To : Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject : Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To : Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject : RE:COVID-19 vacc ine development From: Sent : Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From : Stoffels, Paul [JJCUS] Sent : Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc : Riccobene, Kim [JJCUS) Subject : COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From:Selgrade, Sara (NIH/NIA ID) [El Sent: Wed nesday, February 12, 2020 3:16 PM To : Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc:NIAID OCGR Leg <@mail.nih.gov>; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Sent : (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To : Subject : John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) <@bloomb erg .net>wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From : John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To : (b)(6) Sub j ect : RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From : a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To : J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Sub jec t : RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) <@bloomberg .net> Sent : Monday , February 3, 2020 8 :18 AM To : Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subje ct: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Sent : (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To : Daniel Lucey Subject : Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Sent: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From : Conrad, Patricia (NIH/NIAJD) [E) Sent : Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci <@businesscouncil.com> Sent: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc:Adrienne Ball <@businesscoun cil.com >; Gillian Auger <@bus inesscounc il.com > Subject : Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci <@businesscouncil.com> wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From : Marlene Colucci <@businesscouncil.com > Sent: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject : Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg <@eng.us> Sent: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El <@niaid.nih.gov> Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg <@ama -assn.org> Sent: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject : AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Sent: To : Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Sent: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject : 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Wed, 12 Feb 2020 00:05:00 +0000 To : Subject : Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Sent : Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM <@niaid.nih .gov> Subject : take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Sent : Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM <@niaid.nih .gov> Subject : this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Sent : To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison <@csis.org> Sent : Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll <@csis.org>; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Sent : To : Subject : Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman <@pl et te r .com> Se nt : Tuesday, Februa ry 11, 2020 11:00 AM To : Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject : Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ <@stimes.cn> Sent: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal <@mai lonline .com> Sent: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject : RE: W HO meeti ng Sent: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= from : Nabel, Gary /US Sent: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Sent: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Sent: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Sent: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To : Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Sent: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Sent: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Sent: To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero <@pazienti.it> Sent: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza <@pazienti.it> Subject : Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Se nt: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject : Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : (b)( · Sent: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From : Sent : To: Subj ect : OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Sent : Tuesday, February 11, 2020 7:37 AM To : Fauci, Anthony (NIH/NIAID) [El Subj ect : Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" <@wtop .com > Dat e: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject : WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To : Lisa Monaco Subject : RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Sent: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Sent : To : Cc: (NIH/NIAID) [E];Lerner, Subject : Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From : Routh, Jennifer (NIH/NIAID) [E] Sen t : Monday, February 10, 2020 4:07 PM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Sent : Monday, February 10, 2020 2:37 PM Subject : Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Sent : To : Subject : Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Se nt: Monday, February 10, 2020 3:02 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses <@usasiainstitute .org> Sent : Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject : Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Sent : To: Subject : Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine <@trilateral.org> Sent : Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig <@tr ilateral.org> Subject : Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Sent: To: Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From:Strauss, Eric M.<@abc.com> Sent: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From : Jon LaPook ,.::;....---~ (b ~)~(6) => Sent: Monday , febrnary 10, 2020 10:08 AM To : Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan <@cbsnews.com > ; Jay Shaylor <@cbsnews.com > Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim <@cnn .com > Sent: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From:Lati ka Chugh {WION) <@zeemedia.esselgroup.com> Sent: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc:Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) <@zeemedia.esselgroup (W 10 .com> Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Sent : Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) <@zeemed ia.esselgroup.com >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) <@zeemed ia.esselgroup .com > Sent: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemedia.esselgroup .com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) <@zeemed ia.esselgro up.com> Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Sent : Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) <@zeemed ia.esselgrou p.com >; KUMAR SUNNY <@zeemedia.esselgroup.com > Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) <@zeemed ia.esselgroup.com > Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) <@zeemed ia.esselgrou p.com > Sent : Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY <@zeemed ia.esselgroup. com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) <@zeemed ia.esselgroup .com > Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From:Awwad, David (NIH/NIAID) [CJ Cb)( Sent: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) <@zeemedia.esselgroup.com> Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject : RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) <@zeemedia.esselgroup.com> Sent: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Sent : Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To : Latika Chugh (WION) <@zeemed ia.esselgroup .co m> Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject : Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) <@zeemedia .esselgr oup.com > wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) <@zeemed ia.esselgro up .com > Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subje ct : FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) <@zeemed ia.esselgroup.com > Sent: Tuesday , February 4, 2020 5:15 AM To : Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations<@zeemedia.esselgroup.com> Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Se nt: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" <@turner.com > Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " <@turner .com> Subject : CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Sent: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle <@turne r.com> Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle <@turner .com > wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Sent : Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle <@turner.com > Cc : Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle <@tu rner .com> wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle <@tu rner .com> Subject : Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle <@turne r.com > Sent: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Sent : To: Subject : Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Sent: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subje ct: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Sent: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject : Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To : Folkers, Greg (NIH/NIAID) [E] Subject : RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 1:13 PM Subject : lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Sent : To : Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From : Liz Szabo <@kff.org> Se nt : Saturday, February 8, 2020 7:21 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To : Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Sent : Sunday, February 9, 2020 12:46 PM -----~~ To : Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject : NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Se nt: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject : Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" <@turner.com > Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject : CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To : Subject : If we can do this, I w ou ld be happy to. From:Varon, Sophie <@turner .com> Sent: Sunday, February 9, 2020 12:30 PM To : Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) <@turner .com> Se nt : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Sent: 09 February 2020 16:15 To: Hynds, Joanna (NE) <@turner .com> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject : Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) <@turner .com> wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Sent: 09 February 2020 14:26 To: Hynds, Joanna (NE) <@turner .com > Cc:Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner .com>; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) <@turner .com > wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Sent: 09 February 2020 13 :33 To: Hynds, Joanna (NE) <@turner.com > Cc: Pfeifer, Hazel <@turner.com >; Lovejoy, Hannah (NE) <@turner.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner.com > wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Sent: 09 February 2020 13:00 To: Hynds, Joanna (NE) <@turner .com > Subje ct: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Dat e: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From : "Hynds, Joanna (NE)" <@turner .com > Date : February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" <@turner.c om >, "Lovejoy, Hannah NIH-00203 1 (NE)" <@turn er .com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject : RE: HEART WRENCHINGQUESTION! Will Sent : The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Sent: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Sent: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From:autotell I Sent: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Sent: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From:Stover, Kathy (NIH/NIAID) [E] (b)(6)> Sent: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Sent : Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject : FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve<@cowen .com> Se nt: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil <@cowen.com>; Nedelcovych, Michael <@cowen.com> Subject : Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 9:45 AM Subject : Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Sent: (b)(6) To : Cc: Subject : Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" <@tumer.com> Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" <@tumer.com >, "Lovejoy , Hannah (NE)" <@tumer.com >, "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Sent: 09 February 2020 14:42 To: Hynds, Joanna (NE) <@turner.com> Cc:Pfeifer, Hazel <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) <@turne r.com>wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent: 09 February 2020 14:35 To: Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@t urner .com >; Lovejoy, Hannah (NE) <@turner .com >; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject : Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) <@turne r. com>wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From : Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Se nt: 09 February 2020 13:33 To : Hynds, Joanna (NE) <@turner .com > Cc: Pfeifer, Hazel <@turner .com>; Lovejoy, Hannah (NE) <@turne r.com >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) <@turner .com >wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Sent : 09 February 2020 13:00 To:H ynd~Joanna(NE) <@turner .com > Subject : Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From : " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date : February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject : Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date : February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To : Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject : RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Sent: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) <@turner.com> Se nt : Sunday, February 9, 2020 6:06 AM To : Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) <@turner.com>; Lovejoy, Hannah (NE) <@turner.com> Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Sent : (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To : Subject : Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" <@tumer.com> Dat e: February 9, 2020 at 6:06:15 AM EST ------~~ To : "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" <@turner.com > , "Lovejoy , Hannah (NE)" <@turner.com > Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias <@ikanamed ia.com> Sent: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Se nt: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject : Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To : Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From : Robinson, Sae <@wtop.com> Se nt : Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From : Robinson, Sae <@wtop.com > Sent : Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject : Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal <@wtop .com> wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date : February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" <@wtop .com> Subject : RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal <@wtop .com > Sent: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Sent : To: Cc: Subject : desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From:Awwad, David (NIH/NIAID) [C) Sent: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM <@niaid .nih .gov> Subject : Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To : Conrad, Patricia (NIH/NIAID) [E) Subject : FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Se nt: Saturday, February 8, 2020 11:34 AM Subject : Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From : Griffin, Janelle <@turner.com> Sent : Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject : CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Sent : To: Subject : I am OK with their coming to the house w ithout a truck. I will call you in the AM. From:Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject : Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" <@FOXNEWS.COM> Date : February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Sent: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra <@FOXNEWS.COM> Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra <@foxnews.com > wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" DATE: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Sent : To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Sent: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Sent : Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Sent : (b)(6) To : Subject : RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Se nt : Friday, February 7, 2020 9:03 AM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date : Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Sent: To: Subject : Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Sent: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Sent : To : Subject : Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From : Ian Ingram <@medpagetoday.com> Sent : Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject : Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To : Cc: Subject : Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano <@buzzfeed .com> Sent : Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject : BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Sent : To: Subject : Very interesting! ! From:Folkers, Greg (NIH/NIAID) [E] (b)(6)> Sent: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject : ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From : davidwillman (b)(6) Sent : Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject : Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Sent : To: Subject : Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda <@gannett.com> Se nt: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject : Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject : John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From : Mellors, John W (b) (6) Sent: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject : Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner <@jamanetwork.org> Sent: Thursday, February 6, 2020 6:39 PM To : Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject : FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor <@ama-assn .org > Date : Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork.org >, Annette Flanagin <@jamanetwork.o rg>, Michae l Berkwits <@ama-assn.org >, Brian Shields <@ama -assn.o rg>, Sean O'Donnell NIH-002097 <@ama-assn.erg> Subject : Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner <@jamanetwork.org> Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r <@ama - assn.org> Date : Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner <@jamanetwork .org >, Annette Flanag in <@jamanetwork.org >, Michae l Berkwits <@jamanetwork.org >, Tom Easley <@ama -assn.org >, Brian Shields <@ama -assn.org >, Sean O'Donnell <@ama-assn .org > Subje ct: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Sent: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To : Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Sent: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Sent: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Sent: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Sent : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To : RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Sent : Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Sent: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To : Cc: Patricia {NIH/NIAID) [El Subject : RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Sent: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To : Fauci, Anthony {NIH/NIAID) [El Subject : FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Sent : Wed nesday, February 5, 2020 10 :55 PM To : Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject : Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Sent : Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject : RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Sent : Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject : Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Sent : Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject : Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Sent : To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Sent : Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date : Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb <@gmai l.com> wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Sent : Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subjec t: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner <@jamanetwork .org> Sent: Wednesday , February 5, 2020 6:37 AM To : Fauci , Anthony (NTTI/NIAID) [E] Cc : Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Sent : Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner <@jamanetwork.org> Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner <@jamanetwork.org> Sent: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---Fro m: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Sent: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner <@jama netwo rk.org> Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner <@jamanetvvork .org> Sent: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Sent: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner <@jamanetwork.org >; Phil Fontanarosa <@jamanetwork.org > Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Sent: To : ----------- Subject: Please t ake care of this. From:Larry Schlesinger ----------Sent: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Sent : To: Cc: Subjec t: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Sent: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth <@turner.com> Se nt: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject : treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Subject : FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Sent : Please handle. From : stanley satz (b)(6) Sent : Wednesday, February 5, 2020 7:20 PM To : Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject : Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Sent: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Sent: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) To : Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From:Mak, Tak (b)(6) Sent : Wednesday, February 5, 2020 7:30 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc:Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Sen t: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject : Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date : Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From : Collins, Francis (NIH/OD) [E] (b)(6) Sent : Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From : Jeremy Farrar (b)(6) Sent: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject : Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Sent: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject : FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Sent: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM <@niaid.nih.gov> Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons <@t hehill .com> Sent : Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject : note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Sent: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq <@ntv.ru> Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee <@bbc.co.uk> Sent : Wednesday, February 5, 2020 8:21 AM To : Fauci, Anthony (NIH/NIAID) [El Subject : Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Sent : Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject : Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date : Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" <@mail.nih.gov>, "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject : Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Sent: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject : RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From : Friedel, Laura (Appropriations) Sent: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subje ct: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Sent : Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Sent: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Sent: Thursda y, February 13, 2020 1:31 PM To : Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Sent: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Sent: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Wednesday, February 5, 2020 3:43 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject : RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Sent : Sunday, February 2, 2020 6:11 PM To : Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject : RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Sent : Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject : RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject : RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Sent : Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject : Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Sent : Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject : Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Sent : Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To : (b)(6) Subj ect : FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Sent: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Sent: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Sent: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To : Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Sent: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) <@HHS.GOV> Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject : FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Sent : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Sent : Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Sent : Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subjec t : RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Sent : Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject : FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Sent : Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject : RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From:SCHWARTLANDER,Bernhard F. Sent: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Sent: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject : WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold From : Sent : (b) (5) From : Shapiro, Neil {NIH/OD) [El (b)(6) Sen t : Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From : Collins, Francis (NIH/OD) [El (b)(6) Se nt: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject : RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From : Shapiro, Neil {NIH/OD) [E] Sent: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc:Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject : FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Se nt : Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Sent : Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject : RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Sen t : Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce <@mail.nih.gov>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From : Malliou , Ekaterini (OS/10S) (b)(6)> Sent: Thursday, February 6, 2020 2:25 PM To : Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10<@hhs .gov>; ASPRExec Sec (OS/ASPR)<@hhs .gov> Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject : Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Sent : (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Sent: Thursday, February 6, 2020 4:12 PM To : Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas <@t heat lant ic.com > Sent: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Sent: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To : Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject : RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Sent: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From : Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent : Wednesday, February 5, 2020 3:43 PM To : Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Sent : Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject : RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Sent : Sunday, February 2, 2020 6:11 PM To : Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject : RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Sent : Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject : RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject : RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Sent : Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject : Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Sent : Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject : Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To : Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject : Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Sent : Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sen t : Thursday, February 6, 2020 7:31 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Dat e: Thursday, February 6, 2020 at 1:23:26 AM To : "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" <@hhs .gov > Subject : For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Sent: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" <@hhs.gov > Subject : For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Sent : Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To : Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Sent: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > f rom: Lamourelle , Gabrielle (HHS/OS/OGA) Sent: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Sent: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral <@hhs.gov > Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Sent: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral <@hhs.gov > Subje ct: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Sent : To : Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From:Kerr, Lawrence (HHS/0S/OGA) Sent : Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Sent : (b)(6) To : Subject : Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Sent : Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To : Subject : Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. <@nejm.org>wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From : "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." <@ne j m.org> --------~= Cc:"Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject : RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From : "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To : "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.org > Sent: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subje ct: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Sent : (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To : Subject : Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. <@nejm.org >wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Dat e: Tuesday, February 4, 2020 at 7:06 PM To : "Baden, Lindsey, M .D." <@nejm.org> Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject : RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. <@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." <@nejm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. <@nejm.o rg> Sent: Tuesday, February 4, 2020 12:31 PM To : Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject : favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Sent : To: Subje ct: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY <@ahaber .com .tr> _______ --------=-:-= Sent: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Sent : Wednesday, February 5, 2020 2:58 AM ------------- To : Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subj ec t : Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Sent : To : Cc: Subje ct: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Sent: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject : RE:Coronavirus From: Sent : To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Sent : Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Se nt : Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject : RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Sent: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From : Shapiro, Neil (NIH/OD) [E] Sent: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From : Collins, Francis (NIH/OD) [E] (b)(6) Sent: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject : RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Sent: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject : Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date : Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject : RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci <@businesscouncil.com> Se nt: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein <@carly le.com> Subject : Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Sent : To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani <@ipsos.com> Sent : Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject : Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject : RE:for review: responses for Elemental news site (not urgent) Sent : To: Cc: I made some modifications. You can send it. Th anks. From:Routh, Jennifer (NIH/NIAID) [E) (b)( Sent: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject : for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Sent: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To : Subject : Please handle. -----Original Message----From: Jon M (b) (61 Sent: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From : Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Sent : To : Subject : Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Se nt : Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From:Fleisher, Thomas (NIH/CC/OLM) (V) Sent: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Sent: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Sent: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From:Sylvia Burwell Sent : Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject : A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From:Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Sent: To: Subject : Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From : Rattaphol Onsanit <@v oanews.com > Sent: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To : Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject : FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Folkers, Greg (NIH/N IAID) [E) -------Sent : Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject : WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Sent : Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . Photo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From : Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subj ect : RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From : Baden, Lindsey, M.D.<@nejm.org> Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subj ect : Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) Fro m: "Fauci, Anthony (NIH/ NIAID) [E]" Date : Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm.o rg> Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject : RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.<@ne jm.org> Se nt: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Sent: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject : Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From : Baden, Lindsey, M .D. <@nejm .org > Sent : Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject : Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From : "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." <@nejm.org > Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@ne jm.or g> Sent: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To : Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From : Sent : To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Adam Miller <@cbc.ca> Sent : Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject : Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Sent: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.<@nejm.org> Sent: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject : Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." <@ne jm .org > Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. <@nejm .org> Sent : Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject : favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Sent : To: Subject : Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Sent : Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject : Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From : Sent : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subj ect : FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Sent: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Sent : Tue, 4 Feb 2020 14:32:42 +0000 To : Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner <@jamanetwork.org> Sent : Tuesday, February 4, 2020 9 :19 AM To : Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Sent : Tuesday, February 04, 2020 7:23 AM To : Annette Flanagin <@jamanet w ork .org>; Christiansen, Stacy <@jama network .o rg>; Demetrios Kyriacou <@i amanetwo rk .o rg>; Edward Livingston CbH6>>; Fontanaros, Phil <@jama-archives.org >; GoIub, Robert <@jama-a rchives.org>; Gregory Curfman --------------- NIH-002241 <@jama-archives.org ; Jody Zylke <@jamanetwork .org>; McDermott, Mary (b)(6)>; Mike Berkwits <@jamanetwork .org>; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark <@jamanetwork.o rg>; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub <@jamanetwo rk.org>; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject : Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Sent: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ <@niaid.nih .gov> Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Sent: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) <@n iaid .n i h,gov > Cc: Haskins, Melinda (NIH/NIAID) [E] Subject : RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Sent: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM <@niaid.nih.gov> Cc: Haskins, Melinda (NIH/NIAID) [E] Subject : Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias <@ikanamed ia.com > Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias <@ikanamedia.com> Sent: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias <@ikanamedia .com> wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Sent: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Sent: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject : Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Sent : Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject : Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Sent: To : Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Sent: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To : Fauci, Anthony (NIH/NIAID) [E) Subject : 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Sent: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Sent: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From:Latika Chugh {WION) <@zeemedia.esselgroup.com> Sent: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc:Wion Guest Relations <@zeemedia.esselgroup.com> Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To : Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject : Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Sent : Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To : Fauci, Anthony (NIH/NIAID) [E] Subject : Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Sent: To : Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From:Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Sent : Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From:Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Sent: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Sent: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Sent : Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Sent: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Sent: To : Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Sent: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] <@niaid .nih .gov> Subject : Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Sent: To: Subject : Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Sent: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From : Katz , Ruth <@aspenin stitute.org> Sent: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Sent: Monday, February 3, 2020 11:57 AM To: Katz, Ruth <@aspeninstitute.org> Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth <@aspenin stitute.org> Sent : Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth <@aspeninstitut e.org> -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Sent: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth <@aspeninstitute.org > Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth <@aspenin stitute.org > Sent: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth <@aspenin stitute.org > Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth <@aspeninst itute.org >> Sent : Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth <@aspen institu te.org >> Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org <@aspen insti tute.org > 202-736-5827 NIH-002267 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Sent: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject : coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject : Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Sent : Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Sent: To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle <@th irteen.org> Sent : Friday, January 31, 2020 2:20 PM To : Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject : PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) <@bloomberg .net > Sent: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From : Sent : To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subj ect: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From : Walensky, Loren D.,M.D .,Ph .D. Sent : Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subj ect : RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From : Glimcher, Laurie,M.D . --------------- Se nt: Sunday, February 2, 2020 9:33 PM To : Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject : Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject : Wuhan nCoV Inhibitors Date : January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica <@ansa.it> Sent : Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject : ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Sent: To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From:Joe Palca <@npr.org> Sent: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject : FW: Coronav irus vaccine ------- (b)( From:Joe Palea Sent: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject : RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Sent: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject : Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Sent: To: Subject : Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Sent: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From : Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Sent: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject : Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject : Wuhan nCoV Inhibitors Date : January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Sent : Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc : Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Sent : To : Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Sent : Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To : Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Sent: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Sent: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Sent: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From : Del Rio, Carlos 4 Cb>< ~> Sent: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Sent: Sunday, February 2, 2020 2:00 PM To : Fauci, Anthony {NIH/ NIAID) [E] Subje ct: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To : Cassetti, Cristina (NIH/NIAID) [El Subject : FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Sent : Please handle. From: Robert Jay Rowen (b)( Sent : Sunday, February 2, 2020 4:24 PM To : Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Sent : To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Sent : Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject : RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Sent : Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Sent : Saturday, February 1, 2020 9:02 PM To: NIAID OD AM <@niaid.n ih.gov> Subject : Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To : Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject : RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From : Sent : I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From : Routh, Jennifer (NIH/N IAID) [E] CbH Se nt : Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject : Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From : Rafael C. R. (b) (6)> Sent : Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Sent: To : Cc: Subject : Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From:Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Sent: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject : Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From : Sent : To: Subject : Geeeez --------- From : Billet, Courtney (NIH/NIAID) [E] Se nt: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject : Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From : " M ascola, John (NIH/VRC) [E]" Date : Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject : RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Sent : Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject : RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Sent : Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject : FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From : lssam AHMED <@afp.com > Sent: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject : Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Sent: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From : Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Sent : Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject : Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date : Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subje ct: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From : Jeremy Farrar Sent : Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc:Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From : Jeremy Farrar (b)(6) Sent: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject : RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From : Jeremy Farrar (b)(6) Se nt : Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject : Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" CC: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc:"Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject : My pleasure! From: Goldner, Shannah (NBCUniversal) <@nbcuni.com> Se nt: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject : Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Se nt: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) <@nbcuni. com>; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc : Antoniak, Cynthia (NBCUniversal, MSNBC) <@MSNBC.COM> Subject : [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) <@n bcun i .com> wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From : Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Sent: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) <@nbcun i.com> Subject : [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Se nt: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject : RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Sent: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject : [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) <@nbcun i.com > Sent: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject : Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Sent: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) <@nbcun i.com> Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject : [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) <@nbcuni. com > Sent: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Sent : Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject : RE: Inquiry and possible pone call To : ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From : Daley,George Q. Se nt: Sunday, February 2, 2020 10:32 AM To : Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject : Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Sent : Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Sent: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject : FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Sent: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Sent: To: Subject : Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From : Lorsch, Jon (NIH/NIGMS) [E] Sent: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Sent: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Sent : To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject : More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Sent : To: Subject : Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Se nt: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Sent : To: Subject : Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Se nt : Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject : Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Sent : To : Subje ct : Please handle. From: Jingyue Ju (b)(6) Sent : Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To : Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subje ct : Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From : Arnold Manto (b) ( > Sent : Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject : Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Se nt : Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Sent : To : Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject : FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From:Marlene Colucci <@businesscouncil.com> Sent: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein <@carlyle .com> Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From:Morens, David (NIH/NIAID) [E] Sent: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Sent: To : Subject : Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Sent : Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Sent : To : Subject : Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) <@bloomberg.net> Sent : Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Sent : To: Subject : (b) (4) Please handle. From: Hong Cai (b)(6) Sent : Saturday, February 1, 2020 5:33 PM To: WRB Gmail <@gmail.com>; Fauci, Anthony (NIH/NIAID) [E] Subject : Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date : Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Se nt: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject : Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date : Saturday, 1 Februa ry 2020 at 20:50 To : Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject : Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject : Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From : Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To : Jere my Farrar CbH6J> Cc:"Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From : Jeremy Farrar CbH6J> Dat e: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To : Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Se nt: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject : FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Sent : To: Subject : Yes From: Jeremy Farrar (b)(6) Se nt : Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject : Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From:Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Sent : To : Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From:Albert Rizzo Sent: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc:Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject : Pleasehandle. From:Tatsch, Fernando Franciosi (b)(6)> Sent: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject : RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From:Tatsch, Fernando Franciosi Sent : Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Sent: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Sent: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date : January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From : " Lieberm an, Marc E." <@cbsnews.com> Date : January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject : 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Sent : To: Subject : No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Sent : Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Sent : Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject : ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date : Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" <@n iaid.nih.gov> ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Sent: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" <@b iode fensecomm ission .org > Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From:Asha M. George <@biodefe nsecomm issio n.o rg> Sent : Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject : Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Sent: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George <@b iodefen secomm ission.o rg> Subject : Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" <@bio defe nsecomm ission .o rg > Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Sent : Tuesday, January 28, 2020 5:53 PM (b)(6) To : Asha M . George <@b iode fensecomm issio n.o rg> Subject : Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " <@b iode fensecomm issio n.o rg> Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Sent : Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject : Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Sent: Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Sent : To: Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Se nt: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject : Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Se nt: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov <@hhs.gov > Subject : Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From : andrew igla (b)(6)> Sent : Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov <@hhs .gov > Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From : andrew igla (b)(6)> Sent : Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov <@HHS.gov> Subject : Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From:andrew igla Sent: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Sent: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Sent: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Sent: To: Subject: Attachments : FYI From:Jeremy Farrar (b)(6)> Sent: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From:Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Sent: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To : Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Sent: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject : thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Sent : To : Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Sent: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc:Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Se nt: Saturday, February 1, 2020 10:44 AM Subject : POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Sent: To: Subject : Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From : Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Sent : Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject : FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Sent: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To : Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus update: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Sent : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To : Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subj ect : At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To : Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject : FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From : Sent : We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From : SWAMI NATHAN, Soumya ---------- Se nt: Saturday, February 1, 2020 7:19 AM To : Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject : 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To : 00~ Subject : FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Sent : Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject : 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Sent : To : Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Sent : Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Sent: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject : Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Sent : To : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From : Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Se nt : Friday, January 31, 2020 8:43 PM Subject : Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Sent : To : Subject : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From:Folkers, Greg (NIH/NIAID) [E] (b)(6) Sent: Friday, January 31, 2020 8:43 PM Subject : Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. 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We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Date: Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Date: Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Date: Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Date: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Date: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subject: Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Date: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subject: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Date: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subject: Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subject: (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Date: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Date: Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Date: Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Date: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subject: Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subject: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Date: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subject: ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subject: Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subject: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Date: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Date: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subject: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Date: Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Date: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subject: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Date: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Date: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Date: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subject: NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : From: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subject: W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 From: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subject: RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 From: )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subject: Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Date: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subject: ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Date: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subject: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subject: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Date: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subject: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Date: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subject: RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Date: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Date: Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Date: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Date: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subject: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subject: Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Date: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Date: Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Date: Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----From: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Date: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Date: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subject: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Date: Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subject: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Date: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Subject: Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Date: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Date: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Date: Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Date: Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Date: Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---From: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subject: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subject: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subject: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Date: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis From: Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Date: Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Date: Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subject: FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Paola Dama (b)(6)> Date: Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Date: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subject: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Date: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Date: Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subject: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Date: Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subject: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subject: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Date: Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subject: result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Date: Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Date: Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Date: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subject: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Date: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Date: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subject: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subject: Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subject: Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subject: (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subject: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! From: "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: UpDate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subject: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subject: Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Date: Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subject: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subject: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subject: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig From: Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Date: Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subject: Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Date: Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subject: Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Date: Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Date: 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Date: Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Date: Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Date: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: UpDate: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Date: Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Date: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Date: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Date: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subject: Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subject: urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Date: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Date: Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Date: Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subject: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subject: Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subject: Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subject: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Date: Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: From: "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Date: Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subject: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subject: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Date: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subject: Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subject: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subject: Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Date: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Date: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subject: spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Date: Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subject: impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subject: Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Date: Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subject: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subject: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subject: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subject: Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Date: Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subject: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subject: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Date: Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: From: Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subject: Thanks, Dan. Best, Tony From: Daniel Bednarik Date: Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subject: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subject: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Date: Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached From: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Date: Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subject: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subject: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subject: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Date: Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Date: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subject: REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Date: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) From: "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Date: Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Date: Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subject: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Date: Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subject: RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Date: Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subject: (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subject: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subject: Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subject: From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subject: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subject: RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Date: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Subject: WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subject: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Date: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subject: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Date: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Date: Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subject: Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Date: Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subject: RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Date: Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Date: Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subject: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Date: Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subject: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subject: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subject: M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Date: Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subject: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subject: Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subject: FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subject: (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: From: Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subject: RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Date: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subject: Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Date: Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Date: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subject: COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subject: fyi From: Brendan Taglianetti Date: Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subject: (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subject: It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subject: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subject: Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: From: Karl Simpson Date: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Date: Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Date: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subject: Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: From: "mton-es8@ myse neca.ca " Date: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subject: fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subject: (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Date: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subject: (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Date: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Date: Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Date: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subject: Thanks,John! From: Burklow, John (NIH/OD) [E) -------Date: Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Date: Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Date: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subject: RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Date: Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subject: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Date: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subject: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subject: From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Date: Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subject: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subject: (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subject: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Date: Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subject: At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subject: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Date: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Date: Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subject: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subject: Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Date: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Date: Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Date: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Date: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subject: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Date: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Date: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subject: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Date: Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD To: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Date: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Date: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Date: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Date: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subject: Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Date: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Date: Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Date: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Date: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Date: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Date: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Date: Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Date: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subject: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Date: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Date: Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Date: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Date: Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Date: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subject: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Date: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subject: At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Date: Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: From: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Date: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Date: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Date: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Date: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Date: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subject: FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Date: Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Date: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Date: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Date: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Date: Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Date: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Date: Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Date: Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Date: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subject: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Date: Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Date: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Date: Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Date: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Date: Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Date: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Date: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Date: Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Date: Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Date: Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subject: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Date: Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subject: Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Date: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subject: Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subject: Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Date: Tuesday, February 18, 2020 at 4:52:06 PM Subject: FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Date: Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subject: CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Date: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subject: Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Date: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Date: Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subject: (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Date: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Date: Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Date: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Subject: RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Subject: RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subject: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Date: Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Date: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subject: OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Date: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Date: Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subject: FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Date: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subject: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Date: Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Date: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Date: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Date: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Date: Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Date: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Date: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Date: Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Date: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subject: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subject: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---From: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Date: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Date: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subject: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subject: FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subject: RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Date: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Date: Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Date: Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Date: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Date: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > From: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subject: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subject: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subject: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subject: Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Date: Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Date: Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subject: RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subject: Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subject: FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subject: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subject: RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Date: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Date: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Date: Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subject: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Date: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Date: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Date: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Date: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Date: Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subject: Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subject: Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Date: Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Date: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Date: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Date: Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Date: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Date: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Date: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subject: At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Date: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Se nt : Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Se nt: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Se nt : Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Se nt : Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Dat e: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Se nt: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subje ct : Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Se nt: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subjec t: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Se nt: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subj ect : Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subj ect : Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDate: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDate: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Sen t: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subj ect : (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi upDate: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi upDate: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen Date: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Se nt : Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subj ec t : ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Se nt : Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Se nt : Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Se nt: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subjec t : Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subje ct : Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subjec t: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Se nt: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subj ect : ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subj ect : Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subje ct: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Se nt: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Se nt: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Se nt: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subj ect: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Se nt : Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Se nt: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Se nt: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subje ct: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Se nt: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Se nt: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) Date: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Se nt: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subj ect : NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Se nt : Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Se nt: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : Fro m: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> Date: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subj ect : W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 F r o m: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subjec t : RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE Cc: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 F rom : )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subj e ct : Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Se nt: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subjec t : ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked To: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Se nt: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subj ect: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subjec t: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Se nt: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subje ct: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Se nt: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subj ect : RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . Fro m : Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Dat e: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Se nt : Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Se nt: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Se nt: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subje ct: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subjec t : Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Se nt: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subj ect : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Se nt : Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Se nt : Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----Fr om: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Se nt: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subjec t: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Se nt: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subjec t: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailTo: , Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subjec t : NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Se nt: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Se nt: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Sub j ect : Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Se nt: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Se nt: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Se nt: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Se nt: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Se nt : Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Se nt : Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Se nt : Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---Fr om: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subj ect : Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subje ct: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subj ect: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subj ect: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subj ect: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Sen t: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis Fro m : Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subje ct : OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Se nt : Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Se nt : Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subje ct : FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fro m : Paola Dama (b)(6)> Se nt : Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Se nt: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subj ect: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subje ct: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Se nt : Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subje ct: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Sen t: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Sen t : Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Se nt : Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subje ct: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Se nt : Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct : RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subjec t : FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subje ct: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 ATo: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Se nt : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Se nt : Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subj ect: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Se nt : Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subjec t : result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Se nt : Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Se nt : Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Se nt: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subj ec t: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Dat e: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Dat e: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subje ct : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subje ct: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subje ct : Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subjec t : Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subjec t : (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subjec t: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! Fr om : "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: Upd ate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Se nt: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subje ct: UpDate: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subj ect : Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Se nt : Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards From: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Se nt : Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subje ct: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subje ct: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subje ct: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subje ct: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig Fro m : Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Se nt : Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subjec t : Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Se nt : Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subjec t : Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Se nt : Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Sen t : 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Se nt : Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Se nt : Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Se nt: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Updat e: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Se nt : Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subje ct: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Se nt: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( Date: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Se nt: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Sen t: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Se nt : Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Dat e: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subje ct : Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subjec t : urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. PhoTo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. PhoTo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Sen t: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Se nt : Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Se nt : Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subjec t: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subjec t : Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subjec t : Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subje ct: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) UpDate: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Se nt : Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: Fr om : "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Sen t : Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subje ct: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subje ct: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" Cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Se nt: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subj e ct : Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: UpDate: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: UpDate: Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. Fro m : Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subjec t: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subje ct : Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subjec t : Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Se nt: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Dat e: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subje ct : spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Se nt : Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subj ect : impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviaTo: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) OggetTo: RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviaTo: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] OggetTo: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviaTo: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) OggetTo: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subje ct : Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Se nt : Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subj ect: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subje ct: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subje ct: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subjec t : Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Se nt : Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subjec t: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Se nt : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Se nt: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subje ct: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp Cc: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Se nt : Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: Fr om : Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subjec t : Thanks, Dan. Best, Tony From: Daniel Bednarik Se nt : Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subje ct: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subje ct: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Se nt : Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached Fro m: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDate: COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDate: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Se nt : Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subje ct: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subje ct: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subje ct: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > Date: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to Cc: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Se nt : Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Sen t: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subjec t : REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Se nt: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) F rom : "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, Date: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Se nt : Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Se nt : Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subje ct: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Se nt : Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Se nt : Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subjec t : RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Se nt : Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subjec t : (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subje ct: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subjec t : Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subje ct : From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subje ct: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subjec t : RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> OggetTo: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Se nt: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Su bje ct : WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Dat e: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subj ect: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subje ct: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subje ct: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Se nt: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subj ect: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Se nt: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Se nt : Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subjec t : Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Se nt : Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Se nt : Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subje ct : RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Se nt : Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Se nt : Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subje ct: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Se nt : Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subjec t: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subje ct: Gr eetings and an UpDate: VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subjec t : M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Se nt : Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subjec t: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subje ct : Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subje ct : FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subjec t: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subjec t : (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: Fro m : Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subjec t : RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Sen t: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subjec t : Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Se nt : Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Se nt: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subjec t : (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subje ct : COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subjec t : fyi From: Brendan Taglianetti Se nt : Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subjec t : (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subjec t : It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subje ct: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subjec t : Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: F rom: Karl Simpson Dat e: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subjec t : Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Se nt : Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subjec t : FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Sen t: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subjec t : Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: F rom: "mton-es8@ myse neca.ca " Dat e: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subjec t : fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subjec t : (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subje ct: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Sen t: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subjec t : (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Se nt : Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Se nt: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subjec t : RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Se nt : Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici OggetTo: Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Se nt: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subjec t : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subjec t : Thanks,John! From: Burklow, John (NIH/OD) [E) -------Se nt : Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Se nt : Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Se nt: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subje ct: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subjec t : Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subjec t : RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Se nt : Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subj ec t: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Sen t: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subjec t: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subjec t : From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Se nt : Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able To: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subj ect: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subjec t : (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up To: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up To: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subje ct: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Se nt : Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subj ect : Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subj ect : At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subjec t: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Se nt: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Sen t : Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subj e ct: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subj ect : Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Dat e: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Se nt : Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Se nt : Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subjec t : COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier ElemenTo: Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Se nt : Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Se nt: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subje ct: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Se nt: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subj ect : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Se nt: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Se nt: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subje ct: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Se nt : Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailTo: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD T o: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Dat e: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subje ct: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Se nt: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Se nt: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Se nt: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subje ct : Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Se nt: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Se nt : Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Dat e: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Dat e: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Dat e: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Se nt: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Se nt : Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> Date: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----From: Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Dat e: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subjec t: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Se nt: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Se nt : Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Se nt: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Se nt : Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subje ct: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Dat e: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subje ct: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Se nt: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----From: Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subj ect : At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Se nt : Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subj ect : Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: Fro m: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Dat e: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Se nt: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Dat e: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Se nt: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Se nt: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subj ect : FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Se nt : Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Se nt: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Se nt: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subje ct: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Dat e: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Se nt : Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Se nt: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Sen t: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Se nt : Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Dat e : Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Se nt: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subjec t: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Sen t : Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Se nt: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Se nt : Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Se nt: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Se nt : Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Se nt: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih Date: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Se nt: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Se nt : Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Sen t: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Se nt : Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subjec t: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Sen t : Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subje ct: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Se nt : Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subje ct : Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Se nt: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subj ect : Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Se nt: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subj ect : Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Dat e: Tuesday, February 18, 2020 at 4:52:06 PM Subj ect : FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Se nt : Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subje ct : CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Se nt: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subj ect : Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Se nt : Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Se nt : Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Se nt: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Sen t : Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subj ect : (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subj ect : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Se nt: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Se nt : Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE Date: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Se nt: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Sub j ect : RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Sub jec t : RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subje ct: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Se nt : Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= From: Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Se nt: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subj ect : OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subj ect : Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Dat e: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Sen t : Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Se nt: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subje ct : FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Se nt: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subje ct: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Se nt : Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Se nt: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Se nt : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subje ct: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Dat e: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Se nt: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Se nt: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Se nt : Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Dat e: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Se nt: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Se nt : Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Se nt: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" Date: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Se nt : Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) Cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Se nt: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subje ct: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subjec t: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---Fro m: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Se nt: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Sen t: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subje ct: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subj ect : FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subjec t : RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Sen t : Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Se nt: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Se nt : Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Sen t : Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sen t : Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Dat e: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > f rom: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subje ct: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subje ct: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Dat e: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subje ct: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subj ec t : Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subje ct: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Se nt : Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Se nt: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Se nt : Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . PhoTo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subj ect : RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subj ect : Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) Fro m: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Se nt: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subj ect : FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subj ect: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subj ect : RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Se nt: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subje ct: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Se nt : Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Se nt: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subje ct: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Se nt : Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" Cc: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Se nt: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Se nt: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Se nt: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Se nt: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Se nt: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Se nt : Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subje ct : Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subje ct : Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Se nt : Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Se nt: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Dat e: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Se nt: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Se nt : Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Se nt: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Se nt: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Se nt: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus upDate: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subj ect : At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Se nt: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Se nt : Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:49:45 +0000 Haskins, Melinda (NIH/NIAID) [El Selgrade, Sara (NIH/NIAID) [E);Crawford, Chase (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please review: House Oversight Letter on Coronavirus Diagnostics I do not understand why you are asking me to "review" this. Is this an FYI?? From: Haskins, Melinda (NIH/NIAID) [El Date: Thursday, March 5, 2020 9:53 AM (b)( ------~= > To: Fauci, Anthony (NIH/NIAID) [E] Cc: Selgrade, Sara (NIH/NIAID) [E] ; Crawford, Chase (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Please review: House Oversight Letter on Coronavirus Diagnost ics ;.!::::======~= --------- NIH-000960 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:00:23 +0000 Muniz, Maria de Los Angeles 'Birx, Deborah L' RE: National Blood Supply Maria: Thanks for the note . I will bring this us in our discussions Best regards, Tony From: Muniz, Maria de Los Angeles Se nt : Thursday, March 5, 2020 9:53 AM To: Fauci, Anthony (NIH/NIAID) -----[E]=====~~ ~= Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: National Blood Supply -------- Dear Dr. Fauci: I am an ex-alumni from the Department of Transfusion Medicine at the NIH. I am sorry to bother but I wanted to not ify the Coronavirus Task force about potential blood shortages if blood centers get blood drive cancellations due to the fear in the public. We are starting to see this locally and my concern is that other blood centers in the country are facing the same issue. I tried to contact the office of the vice president, and all I could do was to send an email, which might get lost among thousands . I am hoping you see this and perhaps br ing this to the table. Blood centers use updated federal information when educating donors, staff and hospitals but the current fea r is tr iggering blood drive cancellations. This might be experienced nationally and will impact the national blood invento ry. Thank you Maria De Los Angeles Muniz (Angie) , MD Medical Director o 201.389.0439 I c ._____ mmun iz@v italant. org Vitalant Mon tvale Bank 102 Chestnut Ridge Road Montva le, NJ 07645 Cb _ H_ (please call cell phone first) V italant Cleveland Vitalant Cord Blood 333 East Bridge Street 1 Pearl Court Elyria, OH 44035 Allendale, NJ 07401 Community Blood Serv ices, Lifeshare & Blood Systems are now Vi talant. NIH-000964 From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Thu, 5 Mar 2020 21:27:53 +0000 To: NIAIDODAM Subject: FW: 03 04 2020 Or. Anthony Fauci RE Invite to join my head table at Global's AcceptAbility Gala on Wed S/20 Attachment s: 2020 03 GLOBALAcceptAbility Gala Save the Date.pdf Importance: High Date: Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Institute of A ller gy and Infectious Diseases Th e National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy ancl Infectious Diseases (NIAID) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. From: M ichelle Whitten - Global Date: Wednesday, March 4, 2020 10:35 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Ashley Sparhawk ; Marisa Cucuzzella ; Rotrosen, Daniel (NIH/NIA ID) [El (b)(6l; Deckhut, Alison (NIH/NIAID) [El CbH6)>; Rothermel, Annette (NIH/N IAID) [El --------~ (b) (6) = > Subject: 03 04 2020 Dr. Anthony Fauci RE Invite to jo in my head table at Global's AcceptAbi lity Gala on Wed S/20 Importance: High Dear Dr. Fauci, First let me say we are very grateful to everyone at NIH for working to contain the coronavirus, especially your team at the NIAID. Your interviews are articulate and informative - they give Americans some comfort and some concrete ways to t hink about protecting themselves and what to expect. It must be a stressful ti me and we want you to know that we have confidence in our NIH and CDCto contain it and to help stave it off globally as well. NIH-000965 On a happier note, I wanted to reach out and THANK YOU for all you do for our Down Syndrome research through the transformative trans-NIH INCLUDEprogram. It is making a HUGE difference!! To this end, I am writing today in hopes you will be able to join us on Wednesday, May 20th for our AcceptAbili ty Gala at my head table. Attached is our save the date for the event . We are excited to have Caroline Cardenas as our 2020 Ambassador, Rep Pete Stauber as our keynote (b)(6) •--• , and Reps Lucille Roybal-Allard and Jaime Herrera Beutler are Global's Quincy Jones Exceptional Advocacy Awardees. We believe the gala will be quite lovely and meaningfu l to so many . We do understand that attendance cannot be considered if the coronavirus situation worsens. However, if things are look ing much better (touch wood) we wou ld be deeply honored if you and our friends from NIAID could attend. Looking forward to hearing from you soon. All the Best, Michelle and family NIH-000966 From: Date: To: Cc: ________ -------~= Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 11:00:39 +0000 (b)(6) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb) _C_ 6);Marston, Hilary (NIH/NIAID) [E) FW: New concerns for our randomized trial What do you think? I see the FDACommissioner every day in person. From: Kalil, Andre C (b)(6)> Date: Wednesday, March 4, 2020 11:27 PM To: Seigel, John (NIH) (El (b)(6)•>; Davey, Richard (NIH/N IAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary {NIH/NIAID) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: New concerns for our randomized trial ~======~~ I want to share with you my concerns before the situation gets worse. I have received many calls from physicians from all over the country about how to get "compassionate use" remdesivir. (b)(4).(b)(5) (b) (4). (b) (5) I would appreciate hearing your thoughts on this critical issue. NIH-000967 Best, Andre Andre Kalil, MD, MPH , FACP , FIDSA , FCCM Professor Departmentof Internal Medicine Division of InfectiousDiseases Director, Transplant ID Program Associate Editor, CMI, Official Journal of ESCMID Editorial Board, CCM, Official Journal of SCCM ~ UNMc · ~ rcitlflL • University of Nebraska Med ical Center 985400 Nebraska Medical Center, Omaha, NE 68198-5400 === UNMC (b= )( ~ 6)~1=fax 402.559-5581 (b)(6) I Facebook I Tw itter I YouTube I Flickr "Lucky? Obv iously you haven 't heard anyth ing I've said . It was a matter of app lying Bayes' Theo rem to est imate the condit ional probab ilities . Giving due we ight to the prio r probabi lities ..." Robert Ludlum - The Amble r Warn ing The informat ion in th is e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-ma il by mistake, please delete it and immediately contact the sender. NIH-000968 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:29:00 +0000 Dave Doern RE:Go Tony Dave: Many thanks for your kind note. I hope that all is well with you. Best regards , Tony -----Original Message- ---From: Dave Doern.=-------(b =)~(= 6) Date: Wednesday, March 4, 2020 12:l..9-'P.;;... M.;;...... ___ To: Fauci, Anthony (NTH/NIAID) [E] (b)(6)> Subject: Go Tony ~~ (b)(6) ; Fauci, Anthony Tony, You always do the right thing ......comforting for all your coronavirus attack .... We'll do the praying and you go Keep doing the liard work .... . Thanks, Dave DavidDoem Sent from my iPhone (b)(6) NIH-000969 (NIH/NIA ID) [E] From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 03:19:47 +0000 To: (b)(6) --------- Cc: Subject: Greg Folkers Cb)<) RE: Conference Planning with respect to coronavirus. There is no way of knowing for sure. I would wait unti l May and see what the dynamics of the outbreak are globally and make your decision then whether or not to cancel. From: (b)(6) Date: Wednesday, March 4, 2020 5:46 PM To: Fauci, Anthony (NIH/NIAID) ------- [E ~= (b)(6) Subject: Conference Planning wit h respect to coronavirus. Dear Dr. Fauci Dr. Miriam Ke lty forme rly of NIH referred me to you . I am on the board of d irectors and planning committee of the Applied Superconductivity Conference that is planned to be held in Tampa, Florida the last week of July. Over 50% of our expected 1500 attendees are from outside the continental US. Our planning committee appears to have three options : 1. Hold the conference on the original dates 2. Postpone the conference a few months 3. Cancel the confe rence It would be most helpful to decision process if you can give us a prediction (anonymously of co urse) of how the effects of the virus will pan out. I look forward to your reply . Bruce Strauss ScD, MBA, PE, F-IEEE NIH-000970 To: Fauci,Anthony (NIH/NIAIO) [E) Thu, 5 Mar 2020 02:59:22 +0000 Aliantha Angel Subject: RE:A humble request for your wisdom From: Date: (b)(6) From: Aliantha Angel (b)(6) Date: Wednesday, March 4, 2020 9:55 PM To: Fauci,Anthony (NIH/NIAID) [E) ------:a (b =H=6)> Subject: Re: A humble request for your wisdom Oh my God ... I honestly never expected you to reply and I thank you from the bottom of my heart for being so generous! (b)(6) Is there anything I can do for you besides being grateful? You and yours are in my prayers! much love, Aliantha On Wed, Mar 4, 2020 at 9:45 PM Fauci, Anth ony (NIH/N IAID) [E) -------- (b) ~ > wrote : Dear Ms. Angel: The severe complication of coronavirus are heavily skewed towards the elderly and those with underlying conditions (Heart disease, Chronic lung disease, kidney disease, diabetes, etc.) Most of the pneumon ias are pu re viral pneumonia and so this vaccination w ill not help that. However, on the chance that you have a pure viral pneumonia that gets secondari ly complicated by a bacterial pneumonia (pneumococcal) the vaccine would be beneficial. If you are 65 years of age or older, you shou ld get the pneumonvax23 vaccine anyway regardless of the risk of coronavirus infection. Thanks, Tony From: Aliantha Angel Date: Wednesday, March 4, 2020 8:44 PM (b)(6) NIH-00097 1 To: Fauci, Anthony (NIH/NIAID) [E] Subject: A humble request for your wisdom -------- (b)(6)> Good evening! I know you must be completely busy and inundated with people want ing your time. I apologize that I have nothing to offer in return and completely understand if you don't have time to answer. I called the CDCbut they were totally unhelpful. I have a question that makes sense to me and I was hoping you could answer and the answer might help a lot of people. I understand that over time I, and everyone else, will very likely get COVI0-19 and that most people won't even realize it because it will be minor. I get that, so th is is not a panicked q uestion. I also understand that while most cases wil l not be severe, the bad cases are compl icated by pneumonia . So my question is: If someone has been vaccinated against pneumonia, will that offer any protection in the event that they do contract COVID-19 and perhaps provide some barrier against the worst effects? Thank you for your time if you have read this and I apologize if this is just another in a long line of ignorant questions, but it made sense in my brain so I thought I would at least ask. Be well, be happy, and may life be kind and generous to you, those you love, and those who love you! sincerely, Aliantha Angel NIH-000972 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Thu, 5 Mar 2020 02:50:29 +0000 Gordon, Joshua (NIH/NIMH) [E] RE:Question re: (b)(6) coronavirus case ------- Josh: You should counsel the rabbi to cancel the services this (b)(6) local/city/state health departments (b)(6) doing any contact tracing? Are the Tony -------- From: Gordon, Joshua (N IH/NIMH) [El Date: Wednesday, March 4, 2020 9:44 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Tabak, Lawrence (NIH/OD) [E] (b)( Subject: Question re: (b)(6)> :;.::::======~~Collins, Francis (NIH/OD) [E] (b)(6) --------- ------- (b)(6)>; (b) (6) coronavirus case Dear Tony, I know you are swamped but --------------- (b)(6) (b)(6) Is my reasoning sound? Should I counsel them to cancel services this Friday/Saturday? I'm hoping you can spare a bit of time for this advice, (b)( Best, Josh PS ----------------------------- PPSgreat job today in the hearing NIH-000973 (b)(6) Joshua A Gordon, MD, PhD Director National Institute of Mental Health NIH-000974 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:47:27 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Or. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Do you think that we can do this? I like Jennifer Ashton. From: Strauss, Eric M.< Eric.M .St rauss@abc.com> Date: Wed nesday, Marc h 4, 2020 9:45 PM To: Oplinger, Anne {NIH/NIAID) [E)-------=-c ======~ (b~ )( ~6);---------- (b)(6) ; (b) '""' (6) = >; Conrad, Patricia {NIH/NIAID) [E) Fauci, Anthony {NIH/NIAID) [El Subject: Dr. Fauci for ABC News 20/20, Friday 9pm Ashton/ Muir Hello: I wanted to make sure you are still consideri ng our request for Dr. Ashton and David Muir to interview Dr. Fauci for our 2 hour program ABC News 20/20 Friday from 9pm to 11pm. If a remot e interv iew from a studio -on-t he go mobile unit is prefer able we can certa inly arrange t hat . Thank you for your consideration . Keep up with our latest on the developingnovel coronavirusoutbreak: https ://abcnews.go.com/Health/coronavirus Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss.com Phone: Cb) (6) Connecton Social: T/1/F = @ericMstrauss NIH-000975 Fauci,Anthony (NIH/NIAID) [E) Thu, 5 Mar 2020 02:36:30 +0000 RichSilverman RE:CoronavirusQuestion From: Date: To: Subject: Richard: Right!! Even if there was no coronavirus threat, ---------------- (b)(6) Best regards, Tony From: RichSilverman Date: Wednesday,March 4, 2020 8:56 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Question (b)(6) --------=-:-:-= (b)(6)> Dear Dr. Fauci, I apologize in advance for this email. I am sure you are too busy these days to answer coronavirus questions from the general public. However, you are the only individual I know of who can be trusted to speak intelligently about the pandemic. I know there is no preventive vaccine or cure, and there probably won't be for quite some time-despite what our ersatz President says. But there is something I don't understand. Since the coronavirus causes pneumonia, wouldn't it be a good idea to vaccinate more of the general population with Pneumova x 23 or Prevnar 13? That certainly wouldn't prevent people from catching coronavirus, but perhaps the resulting penumonia onsets might be a little weaker/short-lived? (b)(6) I figured it couldn't hurt, right? Bravo for your efforts to keep our population intelligen tly informed on this situation. Sincerely Richard E. Silverman (b)(6) NIH-000976 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Thu, 5 Mar 2020 00:10:39 +0000 To: Basser, Peter (NIH/NICHD) [E] RE: genetic screen ing Subject: Peter: Thanks for the note. This would not be feasib le in an outbreak setting if you are talking about GWAS or any kind of sequencing. Things would be moving too quickly . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Basser, Peter (NIH/NICHD) [E] Date: Wednesday, Marc h 4, 2020 6:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject ; genetic screening --------------~~ -------- (b)(6) (b)(6) Dear Dr. Fauci, I watched you and Dr. Collins (via videocast) with admiration and pride yesterday during President Trump's visit to the NIH. This morning, (b)(6) and I were discussing the spread of COVID-19. We were opining about why some people only have mild symptoms while others go on to develop ARDS. While 5> we understand that age is a factor, we wondered CbH (b) (5) NIH-000978 (b) (5) Regards, Peter J. Basser, Ph.D. Senior Investigator, Intramural Research Program (IRP), NIH Head , Section on Quantitative lm aging and Tissue Sciences (SQ ITS) Associate Scientific Director (ASD), Division oflmaging, Behavior and Genomic Integrity (DIBGI) Eunice Kennedy Shriver National Institute of Child Health and Human Development (N1CHD) National Institut es of Health (NIH) 13 South Drive, MSC 5772 Bldg. 13,Rm.3W16 Bethesda , MD 20892-5772 USA (b) (6) (0) (30 I) 480-0 I 63 (office FAX) (b)(6) https :f/science.nicb d.nih .gov/confluence /disp lay/sq its/Home ***************************** ************** ******************** ******* This email and any files transmitted with it are confident ial and intended sole ly for the use of the individual or entity to whom they are addressed . If you have received this email in error please notify me a11dthe system manager immedi ate ly. NIH-000979 From: (b)(6) Date: Wed, 4 Mar 2020 18:25:52 -0500 Marc Reinoso Re: Coronavirus Covid 19 and smoking To: Subject: Smoking is terr ible under any circumstance > On Mar 4, 2020, at 6:04 PM, Marc Reinoso > -------- (b) (6) > wrote: > Hello Dr. Fauci , > 1u my review of data it appears there is a negative associat ion with smoki ng . Shou Id smoking cessat ion be menti oned during public announcement s to help discourage smoking ? > > Thank you, > > Marc Reinoso MD NIH-000980 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAIO) [El Wed, 4 Mar 2020 21:27:42 +0000 NIAIDODAM FW: Meeting to AssessEvaluation of COVID-19vaccine candidates for risk of To: Subject: enhanced disease Attachments: March 12th-Tentative list of questions to be discussed_JPCmg-sb[16212lversion4March-1239-CLEAN.docx,Draft agenda.AceAssessED.4Mar20201l_w ith annexes.pdf Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Direc tor Nat ional Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy ancl Infectious Diseases (NIAID ) shall not accept liabil ity for any statement macle that are sencler"s own ancl not expressly macle on behalf of the NIAID by one of its representatives. (b)(6) From: Steve Black Date: Wednesday, March 4, 2020 4:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVI0-19 vaccine candidates for risk of enhanced disease --------- ------~~ -------- Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine cand idat es. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern tim e each day. Participants in the meet ing are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively invo lve the partic ipants on the agenda the first day NIH-000981 and on the second day the meeting will be open for several peer reviewers including Stanley Plotkin and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invit e you to consider joining on day two as one of our formal peer reviewers. The goal of the meeting would be to share recommendations with CEPI COVID-19 developers as well as other interested parties. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hear ing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000982 From: Date: Conrad, Patricia (NIH/NIAID) [E)on behalf of Fauci,Anthony (NIH/NIAID) [E) Wed, 4 Mar 2020 21:16:44 +0000 NIAIDODAM FW: TIME 100 Summit To: Subject: Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alice Park Date: Monday, March 2, 2020 6:19 PM To: Faud, Anthony (NIH/NIAID) [E]______ Subject: TIME 100 Summit Cb _H_6) Hi Dr. Fauci -- as we discussed, sending along an invitation for you to partic ipate in our TIME 100 Summit, which will be held in New York on April 21-22 . We would welcome your insights on a panel addressing COVID-19, like ly moderated by me. I certa inly hope you wi ll be able to join us; please let me know eithe r way. Looking forward to hear ing from you. Best, Alice PLEASENOTE NEW PHONE NUMBER Alice Park TI ME (b)(6) alice.park@time.com @aliceparkny NIH-000983 From: Date: To: Subject: (b)(6) Wed, 4 Mar 2020 09:46:55 -0500 M ichael Gerson Re: Coronavirus Live Updates: Fatality Rate of Covid-19 Is Higher Than the Flu - The New York Times Talk later. Am in Hearing > > ---------- On Mar 4, 2020, at 8: LOAM, Michael Gerson (b) (6) > > Can this be true? > https://www.nytimes.com/2020/03/04/worlcVcoronavirus -news.html NIH-000984 wrote: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 11:21:47 +0000 To: Emanuel, Ezekiel J Subject: RE: RE: From: No evidence in this regard, but you would assume that their would be substantial immunity post infection. It is an RNA virus and so you can expect mutations, but not sure how much is going on. Will have to check. From: Emanuel, Ezekiel J Date: Wednesday, March 4, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ------ -:-::~ (b)(6) Subject: Re: RE: Sorry the phone. Is a person likely to be immune once they caught the corocnav irus once? Do we know anything about likely drift? Ezek iel J. Emanuel, M.D. , Ph.D. Vice Provost of Global Initiatives Chair, Department of Medical Ethics and Health Policy (on Leave 2019-2020) Levy University Professor Co-Director , Healthcare Transformation Institute Perelman School of Medicine and The Wha1ton School University of Pennsylvania Phone: (b)(6) -------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 10:57 PM (b)(6)> NIH-000985 To: Emanuel, Ezekiel J Subject: RE: --------- (b)(6) Thanks for the note. I do not understand your question , See spelling below -----Original Message----From: Emanuel, Ezekiel J Date: Tuesday, March 3, 2020 9:59 AM To: Fauci, Anthony (NIH/N IAID) [E] -------=- -------~~ --------- (b)(6) (be)( = > Subject: Tony Hope they are greatng you better about media appearances after my call with trump. You were great at then press conference yesterday Question:. Lilelynimmunitynince a person has the Coronavirus infection?. Ari is pestering me Ezekiel J. Emanuel, M.D. Ph.D. (b)(6) NIH-000986 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:19:58 -0500 NIAID Public Inquiries Fwd: ------------- (b)(6) Sent from my iPhone Begin forwarded message: From: Patti Taylor (b) C Date: March 4, 2020 at 12:30 :52 AM EST -------~~ To: "Fauci , Anthony (NIH/NlAID ) [E]" Subject: (b) (6) (b)(6 J:- Dr Fauci My name is Patt i Tay lor and I' m a nurse. Been one for 30 years . (b)(6) . Sounds too simple. Anyway I was thinking of the Coronavirus and maybe it has some thing like an autoinunune part to it that makes a person unable to fight back. .... Just a thought. I think a lot. Sent from my iPhone NIH-000987 (b)(6) From: Date: Subject: Wed, 4 Mar 2020 06:19:08 -0500 Cassetti, Cristina (NIH/NIA ID) [E] Fwd: Attachments : PastedGraphic-1.tiff, ATT0000l.htm, To: -----------------------___ (b)(4) _. (b)(4)Executive Summary.pdf, ATT00002.htm Pls respond Sent from my iPhone Begin forwarded m essage: From: "Gupta, Sanchay" Date: March 4, 2020 at l :40:30 AM EST To: "Fauci , Anthony (NIH/NIAID) [E]" Cc: Shaheer Piracha Subject: Meeting Request - (b)(6) ------------- --- -------= = (bH6J (b)(6) (b) (4) Hi Dr. Fauci, (b) (4) I1iaiiKyou m advance for your lllle. Very Best, Sanch ay Gupta (b) (4) NIH-000988 Ce ll (b)( 6J NIH-000989 From: (b)(6) Date: To: Subject: Wed, 4 Mar 2020 06:17:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Pressinquiry_Russia Sent from my iPhone Beg in forwarded messag e: From: Banepm1 Ilonoaa Date: March 4, 2020 at 5: 13:38 AM EST ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Press inquiry_Russia --------------- -------- (b) (6) --;;-~ (b)( Dear Dr Anthony S Fauci , My name is Vale ria Popova , I am the senior editor of Channe l One (Russia). We would like to invite you to take part in the popular international Russian-American projec t on Channe l One. The big game is a televis ion program, within the framewo rk of which two p oints of view on international eve nts are presented : American and Russian. One of the presenters of the program is Dmitry Simes, chairman of the Nixon Center, a US citizen. He was foreign policy adviser to former US President Richard N ixon . Only high-ranking officia ls part icipate in this discussion : presidents, diplomat s, heads of ministries. This is an honest and reasona ble discussion. It would be a great honor for us if you j oined her and discass w ith our experts about situation with coronavi rns. We work live and can use teleconference or skype for comm unication . Hope to cooperate! Channel One is the broadcasting leader in the Russian Federation. 250 million viewers in Russia and abroad. Today, Channel One programs have the opportunity to watc h 98.8% of Russians and more than 250 million people in the world. Channel One is the recognized leader of the Russian telev ision, the most popular and favorite Russian-language channel in the world. It started broadcasting in April 1995 NIH-000990 and became the successo r to the state television and radio company Ostankino , which was the main broadcaster in the USSR and covered 99.8% of the population of Russia. Channel One' s daily programs: the best entertainment shows, unique docum entaries , latest news and analytics , the most headline movies and TV premieres , exclusive sports broadcasts and popular Russian music. Channe l One combines innovative television broadcasting concepts, the vastest national traditions and cutting-ed ge global trends in a unique format. Hope to cooperate! Sincerely , Val eria Po~ r (b) (6) NIH-00099 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:09:35 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E] RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Let us discuss the feasibi lity, desirability and potentia l for clearance or not. --------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, March 3, 2020 8:06 PM ------~~ To: Fauci, Anthony (NIH/ NIAID) [El Cc: Routh, Jennifer {NIH/NIAID) [El======= (b)(6)> (b)(6)] (b)(6)> (b ~~~(6) = >; Folkers, Greg {NIH/NIA ID) [El Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ Just making sure you received Christie Johnson CNN Worldwide Senior Editoria l Producer C: CbH6) Christie.Johnson@tumer.com www.cnn.com From: Johnson, Christie Se nt: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia {NIH/NIA ID) [E) (b)(6) Subject: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci -------~~ As promised, here is the big ticket item I wanted to flag for you . I was wait ing to get through yesterday's hits to loop you in as to not overwhelm you. I have been speak ing with the WH and VP's office to see if Dr. Fauci is availab le to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he's avail? Info : NIH-000992 We are reaching out to invite Dr. Fauci to join Anderson Coope r and Dr. Sanjay Gupta as our featured guest on th e upcom ing CNN specia l town hall - Coronavirus: Facts and Fears . TH E LA TEST : This Global Town Hall program will broadcast in front of a live audience from IOprnMidn ight EST on Th urs day March 5 from th e CNN studios in New York City. We would cove r all expenses for someone from the task force to join us live in NY. If Dr. Fauci is unable to come to NY, we will take him remote ly from DC. Coronavirus: Facts and Fea rs will fea ture interviews wi th a wide range of front-line experts fighting to contain coronavirus , along with patien ts and others who have been directly impacted by it 's spread. We 're rea lly hoping to includ e a voice from the administration in order to comfo rt and inform our worldwide audience. Tho ughts? Thank you! Christie John son CNN Worldwide Sen ior Editorial Producer C: CbH6J Chris tie.John son@tumer.com www .cnn.com NIH-000993 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 03:08:49 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci No. This is not what I was talking about. I received a text from Governor Cuomo of NY State and he wants me to come up to NYCfor a Press Conference with his Heal th Commissioner, Howard Zuycker. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, March 3, 2020 8:06 PM To: Fauci, Anthony (NIH/NIAID) (E) (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) (E)=======~ (b~) = ~; Folkers, Greg (NIH/N IAID) [E) (b)(6)> Subject: FW: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci ------ == Is this what you are talking about? Seriously recommend from wdc but again this is really late - 10 pm to midnight . From: Johnson, Christie Date: Tuesday, March 3, 2020 6:45 PM To: Conrad, Patricia (NIH/NIA ID) [EJ --------,;(b"" H=6> Subject: Re: CNN Global Coronavirus Town Hall/ Thursday/ Dr. Fauci Just making sure you received Christie John son CNN Worldwide Senior Editorial Producer C: (bH6> Christie .Johnso n@tumer.c om www.cm 1.com From: Johnson, Christie Date: Tuesday, March 3, 2020 11:16:51 AM To: Conrad, Patricia (NIH/NIA ID) [EJ------~ (b) ,...., (= 6>> Subject: CNN Global Coronavirus Town Hall/ Thursday/ Or. Fauci As promised, here is the big ticket item I wanted to flag for you . [ was waiting to get through yesterday 's hits to loop you in as to not overwhelm you. I have been speaking with the WH and VP's office to see if Dr. Fauci is available to join CNN this Thursday for our global town hall but wanted to make sure you have the info. Would you mind checking to see if he ' s avail? Info: NIH-000994 We are reac hing out to invite Dr. Fauc i to join Anderson Coope r and Dr . Sanjay Gupta as our featu red guest on the upcoming CNN spec ial town hall - Coronavirus : Facts and Fears. THE LATEST: Th is Global Town Hall program will broadcast in front of a live audience from l OpmM idnig ht EST on T hursday March 5 from th e CNN studios in New York City. We would cover all expenses for someone from the task force to j oin us live in NY. If Dr. Fa uci is unable to come to NY, we will take him remotely from DC. Coronavirus: Facts and Fears will feature interviewswith a wide range of front-line experts fighting to contain corona virus, along with patients and others who have been djrectly impacte d by it 's spread. We're rea lly hoping to include a vo ice from the administra tion in order to comfort and inform our worldwide audience. Thoughts ? Thank you! Christie John son CNN Worldwide Senior Editori al Produc er C (b)C6) Christie.Johnson@turner.com www .cnn .com NIH-000995 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02 :55:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Covid-19 Vaccine Press Release Preview - EIN Presswire - Press Release Distribution Service.pdf Please t ake a look at this and act accordingly From: KUMAR SHAH, MD (b)(6)> Date: Tuesday, March 3, 2020 9 :48 PM To: Fauci, Anthony (NIH/NIAID) [E)______ """ (b"""" )(=6) Subject: Re: Covid-19 Vaccine To Dr Anthony Fauci, Director NIAID/NIH (b)(6) Dear Sir, Humbly, Endocrine Technology, LLCis pleased to forward the enclosed press release for your comments and advice. Best, Kuma r Shah, M .D. Diplomate American Board of Internal Medicine Endocrinology, Diabetes & Metabolism 326 Livingston St, Suite A Brooklyn, N. Y 11217 Office: 718-222-1065; c: (b)(6): Fx:718-222-1350 www .etdiabetes .com NIH-000996 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 4 Mar 2020 02:27:43 +0000 To: Siegel, Marc Subject: RE: Dr. Marc Siegel: Coronavirus public health response has been handled well; we have right leaders at helm I Fox News Thanks, Marc -----OriginalMessage----From: Siegel, Marc Date: Tuesday, March 3, 2020 9:23 PM To: Fauci, Anthony (NTH/NlAID) [E] ------. ~= (b)(6) > Subject: Dr. Marc Siegel: Coronavirus public health response hasbeen handled well; we have right leaders at helm Fox News https ://www.fox.news .com/op inion/ dr-marc-s i egel -corouaviru s-p ublic-hea Ith-respo nse- bas-b een-ha ndl ed-we! 1-weha ve-right-leade rs-a t-helm Sent from my iPhone NIH-000997 I From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:52:20 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: COVID-19 Webinar Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Prosser Date: Tuesday, March 3, 2020 5:37 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Cb)( ; Mike Ramsay ; David 8. Mayer Subject: COVID-19 Web inar Hello, Dr. Fauci, My name is Donna Prosser, and I am the Chief Clinical Officer at the Patient Safety Movement Foundation. We are planning to host a webinar on Friday, March 6 at 8:00am PSTto update our network on the coronavirus outbreak . Our network consists of 4,710 healthcare organizations across 46 countries, as well as patients, families, individual clinicians, and technology companies across the globe, who partner with us to achieve our goal of eliminating deaths from medica l erro r. During Friday's webinar, we plan to focus on how to keep patients safe from harm during this outbrea k, and would love to have someone with your expertise join the call for a brief comment. Would you by any chance be available and will ing to speak with our network sometime between 8-9am PST?We would be grat eful for any amount of time that you could spare during that hour. Thank you for your consideration! Donna NIH-000998 Donna M. Prosser, DNP, RN, NE-BC , FACHE, BCPA Chief Clinical Officer Patient Safety Movement Foundation p: 949.297. 7066 m: (b)(6) a: 15776 Laguna Canyon Road, Irvine, CA 92618 w: patientsafet y movement. or g e: donna. prosser @patientsafet y movement.or g NIH-000999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:51:35 +0000 Bob lsman RE: How to put COVID-19 statistics in perspective Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Bob lsman CbH6>t> Se nt : Tuesday, March 3, 2020 5 :12 PM ---------=-c-= To: Fauci, (NIH/NIAID) [E] (b)(6) Redfield, Robert R. (CDC/OD) ___ _;_Anthony __ _,:_,;___:.. __ .:,_,:_...:..!:::=~~-:--~--- briefing@nytimes .com ---------------Subject: How to put COVID-19 stat istics in perspective (b) (6); Today (March 3), CNN featured a discussion with NY Gov. Cuomo regard ing a new COVID-19 case in NY City. He happened to note that there are currently about 15,000 patients in NY hospitals with the flu. Although multiple government agencies, scientists and health experts keep remind ing us that there are far more cases, hospitalizations and deat hs each year from influenza tha n t his coronavirus, it strikes me that a more effective, more visual and less fear-producing way of presenting t his information would be to present the current number of cases, hospitalizations and deaths from EACHof these diseases side by side. If the number of flu cases, hospitalizations and/or deaths isn't available on a daily basis, we could use extrapolations based on known rates. I think this would certain ly go a long way to putting the relative risks of t hese diseases in clearer focus. Bob lsman, DDS, MPH NIH-001000 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:50 +0000 Jlevyusa RE: Idea to help with Coronavirus infection Thank yo u fo r yo ur not e. AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jlevyusa (b)(6)> Se nt : Tuesday, March 3, 2020 4 :17 PM -------=c-c= -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Idea to help with Coronavirus infection Dr. Fauci, I first want to thank you for your service and efforts in combating this international health problem. I'm neither a physician or a scientist so please accept my apology if my idea is simplistic or isn't feasible. But I was thinking about some of the information presented on why it seems to be less prevalent in children. One theory is that they are exposed to so many other coronavirus's that they experience crossprotection . So I was wondering if anyone had investigated the idea to flood adults with other, less lethal, coronavirus's as a way to develop some level of immunity? Ideally coronavirus's that are a mat ch to what child ren wou ld be exposed to is what I'm suggesting here. I wou ldn't expect that this wi ll totally protect an adult but it might reduce t he severity of the illness if an adult becomes ill and help while a vaccine and treatments are launched. Thank you for considering this idea. Best, Jeff NIH-00100 1 Jeffrey Levy NIH-001002 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 22:50:07 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: my feeble attempt COVID-19.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mai (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tai Te Wu Date: Tuesday, March 3, 2020 2:11 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) -------~= Subject: my feeble attemp t --------- (b)(6) Dear Dr. Fauci, I have seen you on the television commenting about COVID-19. Therefore, I have decided to squeeze some information out of their nucleotide and amino acid sequences as enclosed. Hope that you may soon find a cure with all the available data on this virus. Best regards. Tai Te Wu NIH-001003 (b)(6) From: Date: Tue, 3 Mar 2020 13:36 :59 -0500 To: Barasch, Kimberly (NIH/NIAID) [C] Subject: Fw d: Informal coro navirus teleconference: agenda+ background documen ts Attachment s: imageOOl.png , ATT00001.htm, 01 March_Chapeau_Crit ical preparedness readiness and response actions for COVID 19_ DRAFT.pdf, ATT00002 .htm , 01 Ma rch_ COVID 2019 response scenarios _DRAFT.pdf, ATT00003.htm , 01 March _Preparing for Widespread Commu nity Transmission _ DRAFT.pdf, ATT00004.htm, 18624 Swisscom Call code.docx, ATTOOOOS.htm For the7 am folder pls Sent from my iPh one Begin forwarded message: From: "KABIR, Sophia" (bH6>l Dat e: March 3, 2020 at 1:35:53 PM EST To: SHOC , Office of the Director-General , "Redfield, Robert R. (CDC/OD)" (b)(6) (b)(6) "Felicity Harvey (b)(6) (b)(6) , Jeremy Farrar "Chris.Elias" (b)( (b)(6) > ' "GREIN, Thomas" (bH , "COX, Paul Michael" .------' "SCHWARTLANDER, Bernhard F." (b)(6) , "MINHAS, Rama n" (b)(6) R. Frieden" -=============-::c:;-----------Ly nn Banks (b)(6) , President I Resolve to Save Lives '---:-----:-:---~-====£:....--~ ~ (b) (6) , , Roby nn Leidig ------- (bH6), "Dr VAN KERK.HOVE, Maria" NIH-001004 (b)(6) "GRAAFF, Peter Jan" (b)(6). , Tarik Mohammed (b)(6) (b)(6) Cb) (6), "POOLE, Marcia" "(SPmig) Carlos Navarro Colorado" Ryan Morhard Cb> C6l, "BRIAND, Sylvie" _______ Cb _H_6) CbH6) "Harries, Jenny" "MORGAN, Oliver" (b)(6)nAwwad , David (NIH/NIAID) [C]" ________ Cb >_<6> _ , , "SIMONSON, Stewart" CbH6) , .----- "SINGER, Pet er Alexander" (b)(6) -...., "(SPmig) Carlos Navarro Colorado" ______ (b)(6) Cc: "RYAN, Michael J." ____ CbH,___"""""' = , Christine Youssef' CbH6), "BOKO, Ivana" Subject: Informal coronavirus teleconference: agenda+ background documents ------- ------- Dear colleagues, On behalf of Mike Ryan, allow me to share with you the following background documents ahead of the informal coronavirus te leconferenc e tomorrow at 13.00 CET: (b) (4) Please find below, the key questions for your consideration and input tomorrow. We do not expect you all to address/speak on all the questions but just as a guide to your thinking and the ones you have views/advice/ideas. (b) (4) NIH-001005 (b) (4) The dial-in number and passcode are attached. If you exper ience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41 227 912 4 90 Best, Sophia -----Ori ginal Appointment---- From: RYAN, Michael J. Se nt: Tuesday, February 25, 2020 10:07 AM To: RYAN, Michael J.; SHOC; Office of the Director -General; Farrar; GREIN, Thomas; COX, Paul Michael; SCHWARTLANDER, Bernhard F.; M INHAS, Raman; (b)(6) MAHJOUR, Jaouad; FALL, lbrahima Soce; Thom as R. Frieden; Elhadj SY; Lynn Banks; President I Resolve to Save Lives; (b)(6) AL-SHORBAJI,Farah; (b)(6); Robynn Leidig; DRURY, Patrick Anthony; Dr VAN KERKHOVE, ----------------- ========~~-:-~--:--:""'.":"'"---:--:--:~ (b)(6) Cheryl Cohen; GRAAFF, Peter Jan; POOLE, Marcia; Tarik Mohammed ; __________________________ Cb _>_ <6JRyan Morhard; BRIAND, Sylvie; MORGAN, Oliver; Harries, Jenny; Awwad, David (NIH/NIAID) [C]; SIMONSON, Stewart Cc: SINGER,Peter Alexander Subje ct : Informal coronavirus teleconference When: Wednesday, February 26, 2020 1:00 PM-2:00 PM (UTC+0l:00) Amsterdam , Berlin, Bern, Rome, Stockholm, Vienna. Wh ere: Upper SHOC {For Call in: please see dial in details attached) Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. NIH-001006 The te leconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial-in number with a passcode is attached . If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOCoperator at; +41227912490 It wou ld be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6) mobi le no. (bH Best, Mike Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) (b)(6) Mobile ------ Website: WHO in eme rgencies I WHO Facebook I WHO Tw itte r HEALTH EMERGENCIES prograi ne 11 NIH-001007 From: Date: (b)(6) To: Subject: Tue, 3 Mar 2020 12:42:58 -0500 Oplinger, Anne (NIH/NIAID) [E] Fwd: Interview request from the Jesuits From Patty on Fauci email. Not for several weeks Sent from my iPhone Begin forwarded mes sage: From: Mike Jordan Laskey Date: March 3, 2020 at 12:32:38 PM EST To: "Fauci , Anthony (NIH/NIAID) [E ] " -------~= Subject: Interview request from the Jesuits CbH6>: Dear Dr. Fauci, I host the AMDG Jesuit Podcast , which reaches a faith-based audience connected to Jesuit institutions around the country . I would love to welcome you onto the show to discuss the coronavirus and how your Jesuit education has shaped your career. It would be great to have 15-20 minutes of your time. Thanks very much for your consideration . Best, Mike Mike Jordan Laskey Senior Communications Manager Jesuit Conference of Canada and the United States 1016 16th Street NW 3rd Floor Washington , DC 20036 202.629.5933 jcucommunications@jesuits .org NIH-001008 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:57:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus and a possible path to a vaccine? Origi n of Co-Vid 19 and possible path to vaccination.pdf, PastedGrap hic-10.tiff Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: expand@omcasa .com Date: Tuesday, March 3, 2020 5:00 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Corona Virus and a possible path to a vaccine? Importance: High -------~~ Dear Dr. Fauci Thank you for helping millions of peop le with your research over the years. The following information was culled from http://poleshift.ning.oom. Perhaps this article may help you and your colleagues develop a vaccine that may combat the Corona Virus. You were the first one I thought of who may be able to deem its worth and explo re its research for practical purposes. Some of the links have included nih.gov so maybe your colleagues have already read this. With my limited medical know ledge, I have taken the liberty to highlight key points that seem important. Wishing you and yours all the best for remaining healthy in Mind, Body & Spirit. Warm Regards & Appreciation, NIH-001009 LizJan LIZ JAN BAmst, CAPS Vaastu Homes instill Harmony, Tranquility, Abundance & Love; featuring Universal Design & Aging in Place for safety, comfort & accessibility. Design & Consultations 540.300.0638 expa nd@OmCasa.com www .OmCasa .com NIH-001010 Fauci, Anthony {NIH/NIAID) [E] Tue, 3 Mar 2020 13:55:34 +0000 Conrad, Patricia (NIH/NIAID) [E] FW: Covid-19 - Navigating the Uncharted From: Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: El Bcheraoui, Charbel Se nt: Tuesday, March 3, 2020 3 :26 AM To: Fauci, Anthony (NIH/NIAID) [E]------ (b)( > ...(b..)(=6) Subjec t: Re: Covid-19 - Navigating the Uncharted Dear Dr. Fauci, Thank you for your useful edito rial published in NEJM last week, it helps confirming that the situation does not need to be as glim as the panic that most people are experiencing. I am writing an editorial and hoping to submit it to The Lancet soon. Differently from NIH/US Government institutes, I have more room for reflection in my viewpoint. For that reason, I was wondering if I can have a call with you to get your opinion/advice on the direction of my editorial. I know how busy you are and I can understand if you do not have the time, but if by chance you are willing to have this call, I'll be happy to share my editorial's draft first. As a background, I am an EISgraduate {class of 2009), and trained by Robert T. Chen. Thanks, Charbel El Bcheraoui, PhD, MSc Head of Evidence-Based Public Health, Center for Internat ional Health Protection, Robert Koch Institute, Nordufer 20, 13353 Berlin, Telephone: (b)( (b)(6) NIH-00 1011 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:54 :16 +0000 NIAID Public Inquiries FW: Zinc gluconate by inhalation for early coronavirus in elderly? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sens itive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Arthur --=----(b ~)- (= Date: Tuesday , March 3, 2020 I :48 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Zinc gluconate by inhalation for early coronavirus in elderly? ------~~ Dr Fauci, Since the elderly 's response to pulmonary coronavirus infection may be impaired, especially in those with a chronic disord er, is ther e any information re: deliverin g by inhalati on, low concentrations of a Zinc salt. Tsthere a potential rati onale in early coronavirus infection to try to minimize serious pneumonia , were such inhalation shown to be reasonably safe? Thank you, Arthur Bobrove , MD Stanford and Palo Alto VA Sent from my iPhone NIH-0010 12 From: Fauci, Anthony (NIH/NIAID) [E) Tue, 3 Mar 2020 13:53 :42 +0000 NIAID Public Inquiries FW: Coronavirus: Six Eyed Sand Spider , Habanero, water , Qi Date: To: Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----..=---~~= From: Lily Carnie (b) ( Date: Tues day, March 3, 2020 12:07 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: Coronavirus: Six Eyed Sand Spider , Habanero . water , Qi ------~~ Dr.Fauci , (b)(6) ---------- . I am an author on a Chinese form of healin g called Qigong (a field l have studied for over 30 years) , and am exp loring Corona virus from the perspective of a combination of tbe venom of the Vietname se Six Eyed Sand Spider (entering the cells externally), Habanero capsaicin enteri ng cells internally , the eleva ted water levels of infants and children and their higher levels of Qi in relat ion to them not getting the diseas e, and Qi from Tradit ional Chinese Medicine, Acupuncture, and Qigong. l believe that the above combination can be beneficial in the study of Corona virus. lam sure you are extremely busy and I am but a simpl e author but I just wanted to lry to touch bases in case the above might help. l live in (b)(6)_ I would be truly honored to hear from you. Lily of the Valley Carnie NIH-0010 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 13:52:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Possible treatment of COVID-19 pneumonia Pis respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Paul Tone, MD (b)(6)> Date: Monday, March 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: Possible treatment of COVID-19 pneumon ia -------=-,-:-= Dear Dr. Fauci, Nitric Oxide (NO) has been shown to contribute to the pathogenesis of influenza virusinduced pneumonia in mouse model (Zablockiene et al., 2012). Zablockiene B, Ambrozaitis A, Kacergius T, Gravenstein S. Implication of nitric oxide in the pathogenesis of influenza virus infection . Biologija 2012; 58(1): 15-25 . NO overproduction in influenza virus pneumonia results from a sustained stimulation of inducible Nitric Oxide Synthase (iNOS) (Akaike et al., 1996). Akaike T, Nog uchi Y, ljiri S, Seto guchi K, Suga M, Zheng YM, Dietzschold 8, Maeda H. Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci US A. 1996 Mar 19; 93(6) :2448-53. NO overproduction in influenza virus-induced pneumonia can generate highly reactive oxygen species, peroxynitrite, via radical coupling reaction of NO with superoxide NIH-00 1014 [resulting from influenza virus-induced increased levels of xanthine oxidase (XO) (Maeda and Akaike, 1998). Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistr y (Mose ). 1998 Jul; 63(7):854-65 Peroxynitrite causes oxidative tissue injury through potent oxidation and nitration reactions of various biomolecules (Akaike and Maeda , 2000) . Akaike T, Maeda H. Nitric oxide and virus infection. Immunolo gy. 2000 Nov; 101 (3):300-8 . The crucial role of NO in influenza virus-induced pneumonia was demonstrated on iNOS gene knockout mice: at inocula sufficient to cause consolidating pneumonia and death in the wild-type control mice, iNOS gene deficient mice survived with little histopathologic evidence of pneumonia (Karupiah et al., 1998). Karu piah G, Chen JH, Mahalin gam 5, Nathan CF, MacMickin g JD. Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med. 1998 Oct 19; 188(8):1541-6 . Both influenza and coronaviruses could have the same pathogenetic mechanism of inducing pneumonia, namely harmful overproduction NO. I would like to present you my innovative idea: Suppressing NO overproduction in COVID-19 complicated to pneumonia with Methylene Blue (MB) Arguments pro: MB is known as a guanylate/guanylyl cyclase inhibitor but it is mainly a NOS inhibitor (nNOS and iNOS) . MB is an inhibitor of superoxide generation by xanthine oxidase and NADH/NADPH oxidases. MB is a small molecule capable to penetrate in tissues and cells MB was administered intravenously in patients with refractory septic shock and Hepatopulmonary Syndrome of advanced liver cirrhosis . MB administered intravenously will definitively reach the cells where NOS is induced by COVID-19 complicated by pneumonia both in animals and humans: NIH-001015 -Airway epithelium (includ ing alveolar epithe lial cells); -Alveolar macrophages ; -Capillary/vascular endothel ium (endothelial cells). MB is an inexpensive medication . MB is non-toxic molecu le in humans There are only a few cases of MB toxicity published in the literature. These cases occurred in very peculiar situations: Hemolytic anemia in patients with G6-PD deficiency Severe neuropathology after intrathecal administration of MB Eye injury after topical use of MB Tissue necrosis due to the extravasation of injected MB Jejunal atresia following intra-amniotic MB Serotonin reuptake inhibit ors (SRl's) interact with MB, causing a serious adver se reaction consistent with serotonin syndrome . Very truly yours, Paul Tone , MD, PhD Internal Medicine and Gastroenterology (b)(6) NIH-001016 From: Date: To: Subject: Please read Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:51:29 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Dr. Fauci. I have a possible reason children are immune to the coronavirus. Pis res pond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Klein (b)(6)> Se nt: Monday, March 2, 2020 10:25 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Dr. Fauci. I have a possible reason childre n are immune to the coronavirus. Please read ------~~ Hello Dr. Fauci. I am a (b) (6) phar macist from Ontario, Canada. I was just reading an article that stated covid-19 cases in children under nine y.o . are almost non-existant . I wondered why , and then an answer dawned o n me . They have an immunity because one of the childhood vaccines all children get is giving them cross immunity to coronavirus as well. A study should be done immediately t o see which one gives cross immuni ty, if indeed tha t is the reason for their seeming immuni ty to this virus. The immunity must wear off over time which is why adults and seniors seem to lack prior immunity and get sick. This hypothesis is certa inly worth investigating . If this is what is happening, maybe millions of lives could be saved by a simple booster of an existing vaccine. Please let me know your t houghts on this matt er. Thanks for your time . Rob Sent from Ma il for Windows 10 NIH-00 1017 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 13:21:11 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Sky News We shou ld discuss Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Szweda, Jakub (Interviews producer) Date: Tuesday, March 3, 2020 6 :16 AM To: Fauci, Anthony (NIH/NIAID) [El Subj ect : Sky News -------::-:-,= (b)((;)> Import ance: High Hello Dr Fauci, Hope you're well. I'm a producer for Sky News, looking after our flagship evening programme Sky News Tonight 7-lOpm UK time (2-Spm ET). I was wondering if you might be available for an interview on the coronavirus outbreak? Either today or another day this week. Happy to exp lain in more detail. Any questions, please let me know . Best, Jakub Jakub Szweda NIH-0010 18 Inten,iews Producer I Sky News Phone : +44 (0)2070320436 I Mobile : (b)(6) Address: 2nd Floor, 4 Millbank , Westminster, SWIP 3JA Watched by 169m people in 138 countries Information in this email including any attachments may be privileged, confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received it in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and externa l networks . SKYand the SKYmarks are trademarks of Sky Limited and Sky International AG and are used under licence. Sky UK Limited (Registration No. 2906991), Sky-In-Home Service Limited (Registration No. 2067075), Sky Subscribers Services Limited (Registration No. 2340150) and Sky CP Limited (Registration No. 9513259) are direct or indirect subsidiaries of Sky Limited (Registration No. 2247735). All of the compan ies mentioned in this paragraph are incorporated in England and Wales and share the same registered office at Grant Way, lsleworth, Middlesex TW7 SQD NIH-001019 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 3 Mar 2020 13:10:22 +0000 To: George GAO Cc: Mascola, John (NIH/VRC) [E);Conrad, Patricia (NIH/NIAID) [E);Gr aham, Barney (NIH/VRC) [ E);Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Vaccine - confidential PPT Attachments : 2020 0303 For Gao laoshi.p ptx George: Thanks for the note. I will send this to Dr. John M ascola Director of the NIAID Vaccine Research Center and Dr. Barney Graham to fo llow-u p with you. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: George GAO Cb)(6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Anthony (NIH/NIAID) [E),_ Subject: Vaccine - confidential PPT ______ _ ------~~ (b)(6) DearTony Hope this email finds you wel l and the US will soon get the COVID-19 down. (b) (4) NIH-001020 All the best George ~ 13ft~ iPhone NIH-001021 From: Date: To: Cc: Subject: Attachments: Fauci,Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 10:57:14 +0000 Mascola, John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [E);Graham, Barney (NIH/VRC)[E) Important - POYUSand VP visit slides VIP visit to VRCCoronavirus Short version - for 3-3-2020.pptx John : Yesterday when I spoke to your IT/audio visual guy I to ld him to pull out the single slide with the comparative time lines for various vaccines over the years and show it on the screen. I then asked him to have the full set of slides ready for me to show . I have now abridged that "fu ll" set so that I can whip through them if it looks like the discuss slows down. I am attaching th is abridged version here. Please ask him to subst itu te this shorter version for the full set from yesterday. Call me if you have any questions. Thanks , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives . NIH-00 1023 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 03:40:19 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Can we get comment please? Date: To: Subject: I am not going to comment. (b)(S) From: Billet, Courtney (NIH/NIAID) [E] -------Date: Monday, March 2, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)(6)> (b")(= '""6); Lane, Cliff (NIH/NIAID) [E] (b) (6)'> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIA ID) [E] Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Re: Can we get comment please? -------- (b)(6)>; (b) (5) From: "Burton, Tom" Date: Monday, March 2, 2020 at 3:09:17 PM To: "Fauci, Anthony (NIH/N IAID) [El" --------=- c-="Lane, Cliff (NIH/NIAID) [E]" (b)(6), (b)( , " Billet, Courtney (NIH/NIAID) [El" -------Subject: Can we get comment please? (b)(6) Folks, we're doing a story that focuses in part on the administration's conference call from last Thursday noon about a decision to send out more CDC coronavirus assays despite the fact that they had become contaminated and compromised. We understand that Dr. Fauci was one of four federal doctors (the others being Drs. Hahn, Shuren and Shah) who strong ly recommended the assays not be sent out. I want to give Dr. Fauci a chance, on or off the record, to comment on the story please. Thank you, Tom Burton Thomas M. Burton, Staff Reporter The Wall Street Journal 1025 Connecticut Ave. N.W., #800 Washington, D.C. 20036 W: 202 862-6611 Follow me @TomBurtonWSJ NIH-001024 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:11:52 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Alert: Questions from Sen. Alexander for tomorrow's From: Date: To: Subject: hearing Bob: Please do me a favor and provide answers to the questions below from Sen. Alexander Thanks, Tony -------- (b)( > From: Haskins, Melinda {NIH/NIAID) [El Date: Monday, March 2, 2020 8:30 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: Crawford, Chase (NIH/NIAID) [El (b)( ; Selgrade, Sara (NIH/NIAID) [El CbH >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) >; Marston, Hilary (b)( > (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/N IAID) [El Subj ect : Alert: Questions from Sen. Alexander for tomorrow's hear ing ------ ..-.-,= Dr. Fauci, We just received a number of questions from Senat e HELPthat Sen. Alexander plans to ask you at the hearing. Chase will pull together the epi info . Let us know if you want to discuss these. Melinda Sent from my iPhone Begin forwarded message: From: "Hallett, Adrienne (NIH/OD) [El" (b)( > Date: March 2, 2020 at 8:15:00 PM EST To: "Haskins, Melinda {NIH/NIAID) [E]" (bH >, "Selgrade, Sara (NIH/NIAID) [E]" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" (b)(6) ---------... ~ ---------- Subject: Fwd: Questi ons from Sen. Alexander See an ticipated questions below. Begin forwarded message: From: "Coulter, Margaret (HELP Committee)" (b)(6) Date: March 2, 2020 at 7:29:15 PM EST To: "Pence, Laura (HHS/ASL)" --------=-cc-c= (b)(6), -------NIH-001030 "Bradsher, Kris (HHS/ASL)" (b)(6)>, "Berkson, Laura (NIH/OD) [E]" ,;___: _ __:_..=:==~::::;;----::~-:-:--(b)( 6) >, "Hallett, Adrienne (NIH/OD) [E]" ======== (b ~ )~(6) ~> Cc: "Bell, Kathryn (HELPCommittee)" ,.:.....:========~:;;-~ CbH >, "Vogt, _ _.:......========~"""'.".""'.""" " Pfaff, Melissa (HELPCommittee)" Andrew (HELPCommittee)" Grace (HELPCommittee)" Subject: Questions from Sen.Alexander (b)(6) (b)(6)>, "Graham, (b)(6)> Hi Laura and team, Thanks for all your work in advance of tomorrow's HELP hearing. Below are specific questions that Sen. Alexander plans to ask Dr. Fauci and would greatly appreciate concise answers to - he is happy to allow Dr. Fauci to elaborate if there is additional time. Add itionally, he plans to ask Dr. Schuchat a few ques tions abo ut CDC covering patient costs from quarantine . Thank you very much and look forward to seeing you all or your colleagues tomorrow. Best, HELP team Questions for Dr. Fauci: 1. How many cases are there in the world? 1nthe U.S.? 2. How many deaths so far in the wo rld? In the U.S.? 3. How many countries have cases of the corona virus? 4 . How do you know if you have the coronav irus? 5. What are the symptoms? 6. How do you protect yourself? 7. Should we all be wearing 8. masks? If not, why should health care workers have to wear masks? 9. What are the most effect ive ways to protect your families? 10. If someone has coronavirus symptoms, what should they do? NIH-001031 11. If a doctor has a patient with these symptoms, what should they do? 12. Who is most at risk ? 13. What is the mortality rate? 14. Can you explain why there have been relatively few reports of cases in children? 15. Th is is the peak of the flu season - a. b. c. d. How many flu cases have we had this year so far? How many deaths have we had this year from the flu? How is the coronavirus different from the seasonal flu? Is it possible that we could reduce the infectio ns or deaths from the seasona l flu because you need to do the same things to protect yourself for both types of viruses? 16. Can a person transmit the virus even if they are not showing symptoms? 17. Are your agencies doing any research to determine when exactly an individua l may transmit the virus to others? QUESTION FOR DR. SCHUCHA T: • If a patient is under a federal government-required quarantine , who pays the bills? • Does their insurance pay first, and then does the CDC cover the remaining bills as the payer of last resort? • If CDC is the payer of last resort, does the agency pay the doctor or the hospital directly - or is the patient obligated to send their bills to the CDC? • How and when is this infom1ation made available to the patients under a federal government-required quarantine? NIH-001032 From: (b)(6) Date: To: Subject: Mon, 2 Mar 2020 19:06:49 -0500 Johnson, Richard Allen,M .D. Re:Telecast today Thanks, D ick. On Mar 2, 2020, at 6:57 PM , Johnson, Richard Allen,M.D. ------------- (b) (6)>wrote: Tony, You were the star of the broadcast today! Your in tell igence, confidence, warmth , and humor are what we all need with COVID-19. Please keep these coming. You appear to have a great working relationsh ip with Dr. Burks. Very best, Dick NIH-001033 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 2 Mar 2020 17:56:05 +0000 M ichael Gerson RE: Q See my edits in red for accuracy Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Michael Gerson --------------= ------- = (b)(6)> Date: Monday, March 2, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Q (b)(6J> Th is is the descript ive portion of my column. I don't want to over or under-state: America is entering a disturbing new stage in the coronavirus outbreak. There has been community spread in at least one and likely two locations in Washington State. And it appears the virus was being transmitted for at least a few weeks before current cases were recognized. So we can expect dozens or hundreds of cases in those locations unl ess contact tracing is especially efficient. That means the disease is loose and easily tran smitted. The crucial issue now is the real mortality rate, which remains uncertain. The stated mortality is 2 percent. American experts are hoping the rate turns out to be considerably lower. But the math remains tro ubling in any case. If only 5 percent of th e population eventually gets infected (which is on the low side of some estimates) and the mortality rat e is 1 perc ent, th ere still would be a few hundred thou sand deaths. NIH-001034 At this stage, the main tool that public health experts have is social distancing - the attempt to keep as many people as possible in affected areas out of sneezing distance from one another. This means measures such as closing schools, cancelling events in theaters and stadiums and encouraging employees to telework. States and localities ultimately make such decisions rather than the federal government. But according to some health experts I consulted, Washington State should be taking such measures right now. The effectiveness of social distancing is limit ed when action comes too late or ends too early. The goal of such policies is to keep the Ro (reproduction ratio) as low as possible. When people are in close proximity, a single infected person can spread the disease to several others, boosting the Ro of the disease as high as 2 to 3 and causing an exponential increase in cases. If the Ro is less than one, the epidemic will gradually decline and stop on its own, with or without a vaccine. A vaccine, however, would be tremendously helpful. There are at least ten vaccine development projects underway. But the one furthest along at the National Institutes of Health (NIH) is still about six weeks away from starting the process of a phase 1 trial in human volunteers that will take 3 to 4 months to complete and to show that the vaccine safe and produces specific antibodies. A phase 2 trial will follow and will take at least 6 to 8 months to determine if the vaccine is efficacious in people at risk for infection . Then production would need to be scaled up by a willing pharmaceutical company to deal with a global crisis. All this in total will take at least a year - assuming there are no unpredicted scientific obstacles in th e way. On Mar 2, 2020, at 7:54 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: CbH> Mike: Social distancing is not really geared to wait for a vaccine. The major point is to prevent easy spread of infections in schools (closing them), crowded events such as theaters, stadiums (cancel events), work places (do te lewor king where possible). States and localities make these decisions, not the Federal government. The goal of social distancing is to prevent a single person who is infected to readily spread to several others, which is facilitated by close contact in crowds. Close proximity of people will keep the ROhigher than 1 and even as high as 2 to 3. If we can get the ROto less than 1, the epidemic will gradually decline and stop on its own without a vaccine. (b)(6) NIH-001035 Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 (b)(~ E-mail, The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Origi naI Message----From: Michael Gerson--------~ (b ~)~(6) => Date: Monday, March 2, 2020 7:22 AM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Re: Q -= (b=H=6) Is the overall strategy for social distancing just to keep the percentage of Americans who get the disease low until a vaccine is available? This seems much harder to do in a free society . Does this mean closing schools? Public transport? Do states and localities make such decisions? (b)(6) On Mar 2, 2020, at 6:11 AM, Fauci, Anthony (NIH/NIA ID) [E] (b)(6)wrote: --------- Mike: Thanks for the note. We are clearly getting "community spread" in at least one and likely two non-contiguous locations. It was likely spreading in Washington State for at least a few weeks before the current cases were recognized, which means we can expect dozens and dozens of cases (or more) in that locat ion unless we are vey lucky and/or the contact tracing is highly efficient. The precise mortality rate is stil l uncertain. The stated NIH-001036 mortality is 2%; however, even if it is half that (1%) and only 5% of the popu lation get infected, you are correct in that we can have a few hundred thousand deaths. The really critical issue is what the mortality rate actually turns out to be. I am hoping for a considerably lower mortality rate, but that might be wishful thinking . Whatever it turns out to be, the major tools that we have are public health measures, particularly social distancing, which we have to start doing right now in Washington State and thinking about in other locations. That is really the major weapon that we have. Even though we go into phase 1 with one candidate vaccien in about 6 weeks, vaccine is out of the question for at least a year or more if you want to make sure that you have an effective vaccine, i.e. some efficacy data before massive deployment. We are meeting with pharmaceutical execut ive today and I will bring up the issue of what the fastest possible time line would be to have a deployable vaccine. (b)(6) ---------- . I hope that you are well. Best regards, Tony -----Original Message----From: Michael Gerson -----------=- (b'"'"' )= (6) Date: Monday, March 2, 2020 5:04 AM To: Fauci, Anthony (NIH/N IAID) (El Subject: Q --------:a~ --------- aa, (bH > Tony, I was with Francis yesterday , and t he news seemed pret t y sobering. It seems like the virus is out in the general population in the Pacific Northwest and Silicon Valley. A pandemic now appears likely. Francis gave me a guesstimate that 5 to 20 percent of t he US population may end up infected . Depending on the mortality rate, this could result in hundreds of thousands of deaths. Not for att ribution in any way, is this a fair summary? How and when wi ll we know if the disease is on this track? Do we have any better info on mortality yet? And is there any news on the vaccine front? As I understand it, we are not even to Phase 1 trials on anything. If a vaccine is promising, are well talking about late Fall as the earliest possibility? And are there any substantive measures that could be taken to make sure pharma steps up to produce a vaccine on a massive scale once we have It? I'm not sure Americans have been adequately prepared for this possibility. That is partl y a political problem (in my view). But what needs to happen soon to get people prepared? Hope you are hold ing up well under all of this and taking care of yourself . NIH-001037 NIH-001038 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 2 Mar 2020 17:26:54 +0000 Reddy, Sumathi RE:? For COVID-19 the mortality rate is approximately 2%. For seasonal influenza it is approximately 0.1% Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Reddy, Sumathi Date: Monday, March 2, 2020 10:49 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,..,= (b)(6) Subject: ? Hi there Wanted to see what's the most up-to-date info you have on mortality rate for covid-19 versus influenza? Sumathi Reddy The Wall Stree t Journal "Y our Hea lth" co lumnist M:.__ _ _, ,..,~c.., (..,,, 0 : +1212416 2945 E: sumathi.reddy@wsj.com T: @rddys um A: 121 1 Avenue of the Ame ricas. New York, NY 10036 NIH-00104 1 (b)(6) From: Date: To: Subject: Mon, 2 Mar 2020 09:24:45 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: 60 Minutes/ COVID -19 Let us discuss Begin forwarded message: From: Denise Cetta (b) ~ Date: March 2, 2020 at 9:20:42 AM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)(6J: Cc: Jon LaPook (b)( , "Stover, Kathy (NIH/NIAID) [E]" (b)(6)>,"Routh, Jenn ifer (NIH/NIAID) [E]" (b)(6), Katie Brennan ------~~ --------Subject: 60 Minutes/ COVID -19 Dr. Fauci: Good morning . I know you are busy, so forgive me for reaching out directly , but time is of the essence. I know you spoke with Jon about doing a 60 Minutes story on COVID-19. We are interested in potentially cra.c;;hinga story for this weekend. Is it possible for us to have a quick brainstorming phone call on what such a story might include if based at NIH with you? Some idea s ... Fallo wing you closely as you engage in meetings, ge ttin g up to date info, giving you1 opinion , going to task force meeting at WH or elsewhere. Are you using the same "DNA platform" you showed us in the Zika story to build a potential vaccine for COVID-19? Or is it another approach? Will you be meeting with any patients who are currently infected? Bringing any patients to the NIH for care/evaluation? Let us know when you can talk . Denise Denise Schrier Cetta Producer CBS News, 60 Minutes Cell : (b)(6) NIH-001042 From: Date: (b)(6) To: Subject: Mon, 2 Mar 2020 09:20:56 -0500 Shlomchik , Mark Jay Re: Is this true? I have been very explicit in stating publicly that I am not being muzzled or censored. I say exactly what I want to say based on scientific evidence, I have stated this on multiple TV programs over the pas t few days including at a major press conference with many, many reporters present including several TV cameras . I could not possibly be more public about this. No censor. No muzzle. Free to speak out. On Mar 2, 2020, at 9 : 11 AM, Shlomchik , Mark Jay wrote: OK, well that is good to know. It has been reported by many outlets including the NYT . So if not true I think it is cr itica lly important for you to say so publicly and show that it is not the case. It is critical, critical that we all have faith in the science and medical leadership. Your personal integrity is at stake here in the community and the world, and is a proxy for the integrity of science and medicine. According to one house member, the following : Garamendi told MSNBC's Hallie Jackson that Anthony Fauci was scheduled to do all five major Sunday talk shows, but says Fauci canceled the appearances after Vice President Pence took over the administration's response to the disease. Trump on Wednesday named Pence as the official overseeing the government's response. "I can repeat what he said, he said, 'I was not muzzled. However, I was to go on the Sunday talk shows five of them. The vice president's office then took over the control of this situation, and told me to stand down, not to do those shows,'" Garamendi said, quoting Fauci. We cannot mince words about this or have nuances. If you were told not to appear on Sunday talk shows, then a reasonable person would have to assume your speech indeed is being contro lled. Whether you call it " muzzled" or censored is a matter of semant ics. Is it factual that you were told/asked not to appear on these shows as had been scheduled? NIH-001043 I hope you understand my reason for and level of concern. I am certain it is shared by many of your colleagues and citizens. Be st, Mark Mark Shlomchik, MD, PhD UPMC Endowed and Distingu ished Professor of Immunology Chair, Department of Immunology University of Pittsburgh School of Medicine W1052 Biomed ical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: Cb)(6) Fax: 412-383-8098 (b)(6) https://www.immunology.pi tt.edu http://immunology.pitt.edu/person/mark- jay-shlomchik-md-phd Check out our gene targeting and flow cores: http ://immunology .pitt.edu/departmentresources On Mar 2, 2020, at 9:03 AM, Fauci, Anthony (NIH/NIAID) [E] Cb)(6)>wrote: The story is not true. I am not being muzzled or censor ed. On Mar 2, 2020 , at 8:51 AM, Shlomchik , Mark Jay wrote: Dear Ton y, Is the inform ation in this article true? https ://www .businessins ider .com/who-is-anthony-fa uci- speech-controlled-by-trump-coronavirus-2020-2 If it is, I think that-in the interests of public health and the integrity of science in the US- you must not acquiesce but instead resign and sp eak out. If it is not tru e, then plea se refute it and set the record straight. Sincerel y, Mark Shlomchik, MD, PhD UPMC Endowed and Distinguished Professor of Immunology Chair , Department of Immunology Unive rsity of Pittsburgh School of Medicine NIH-001044 W1052 Biomedical Science Tower 200 Lothrop St Pittsburgh, PA 15261 Phone: 412-648-8771 Fax: 412-383-8098 mshlomch@p itt.edu https://www .immunoloqy.pitt.edu http://immu noloqy.pitt.edu/pe rson/ma rk-jay-shlomch ik-md-phd Check out our gene targeting and flow cores: http://immuno logy .pitt.edu/department-resources NIH-001045 From: Date: (b)(6) To: Subject: Attachments : Mon, 2 Mar 2020 09:10:54 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: lay info for people who are at risk for COVID-19 Wuhan Coronavirus for Mama.20020301.pdf, ATT000Ol.htm Plea se take a look at this and respond. Begin fo1warded message: From: Cynthia Bristow Date: March 1, 2020 at 10:12:22 PM EST CbH ---------=---c- To: "Fauci , Anthony (NJH/NIAID) [E]" CbH6) Subject: lay info for people who are at risk for COVID -19 Dear Tony, I would like to respectfully ask if someone in your Institute could kindly review the attached precis regard ing the current COVID-19situation and recommend any revisions prior to my disseminating this to my at risk family members including (b) (6) and others in retirement communities who are concerned. I appreciate that this would not be an official endorsement by you . I am only asking if there is anything that you or others think I could add or subtract from this precis to give solace to those who are in need of knowledge and comfo rt. Thank you kindly for your attention to th is matter . Best wishes, Cynthia L. Bristow, PhD Chief Executive Officer Alpha-1 Biologics 25 Health Sciences Drive, Suite 110 Stony Brook, NY 11790-3383 Office (b)(6J (b)(6) Cell phone: (b)(6) www .alphalb iologics.com NIH-001046 From: Fauci, Anthony (NIH/NIAID) [El Date: Mon, 2 Mar 2020 10:43:27 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Attachment s: Agenda Board telcon 4 Mar Fnl.p df, Local_Access_en .pdf FYI From: Amel ie RIOUX Date: Monday, Ma rch 2, 2020 5:29 AM To: Dzau, Victor J. Anthony ( NIH/ N IAI ~ D:) [:E -::":'" ] -:======~ ~====== (b)(6)> (b,:,,: )~ (6) ~;~F-o-re-:H "'." e_n_r":,e- tt-a-=====~ (b)(6) Gashumba Diane (b-::::! )('-=-6)>; Suzuki Yasuhiro-========== (b)( ; Fauci, (b ")~ '.= (6) ,:,::;-:G ::-a-o-:F:-u-- (b)(6); Ilona Kiekbusch (b=)=c ..-- (b)(6) Vega Morales Jeanette (b)(6); VijayRaghavan _:::~= (b)( ; Skvortsova Veronika (b)(6) (b)(6)>; As Sy (b)(6)>; Elhadj SY (b)(6) Tore Godal (b)(6)> ; Godal, Tore (b)(6); (b)(6) SCHWARTLANDER,Bernhard F. (b)(6) ; RYAN, ----:;=====~-Mich ae I J < >; Pate M uha med (b)(6); Kanarek, Morgan (b)(6) Conrad, Patricia -~---~-:-:====================~~--(NIH/NI A ID) [E) (b)(6); (b)(6) (b)( ; 'Sheila Austria' (b)(6) Teresa M iller de Vega (b)(6)>; Marston, Hilary (NIH/NIAID) [El ------======-Krishnaswamy Cc: Gro Brund t land ----=--------'=-==---::-------- ===========~ ~==========:-::=-;------.- --------------- --------~~ --------- Palu Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE: CONFIRMING 4 MARCH TELECONFERENCE Dear Board membe rs, We are confirming the Board te leconfe rence on Wedne sday, 4 March at 14:00 Geneva time . Please find attached the agenda (also copied below) and the call-in numbe rs. The Access code is Please let us know if you have any questions . Thank you very much, NIH-00105 1 (b)( 4) Amel ie Rioux On behalf of the Co-Chairs Participant access Optional dial-in numbers international +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Loca l Access (b) (4) Access via Web Global Preparedness Monitoring Board Teleconference 4 March 2020, 14:00- 15:00 CET Agenda 1. Welcome and Roll call 2. Updates and stock taking on the COVID-19 outbreak o Update from George Fu Gao (TBC) o Update and Proposal from Jeremy Farrar 3. Discussion ; Actions from the Board on the COVID-19 outbreak (30 minutes) 4. Adjourn From: Amelie RIOUX Date: Tuesday, 25 February 2020 10:18 To: Dzau, Victor J. Anthony Fauci (b)(6); Fore Henrietta -o. (b)( 6) >; Gashumba Diane ~======:,ot,_;.,,. (b)(6)>; Suzuki Yasuhiro (b) (6)· --======~-:-----:-:---:----:::::===~~--:::---::------ --"'==,::--------- '========~.;,..= Vega Morales Jeanette -----~====~:':'.= Skvortsova Veronika Krishnaswamy (b)(6)· (b)(6)>; Cc: Gro Brundtland (b)(6)>; (b)(6); As Sy Tore Godal Gao Fu (b)(6); Ilona Kiekbusch CbH~ > ; (b)(6); (b)(6)>; VijayRaghavan (b)(6) (b)(6)>; Elhadj SY Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. < (b)(6)>; RYAN, Cb _ >_C6) _ >; Pate Muha med <1 CbH6l>; Kanarek, Morgan (b)( >; ~-:----:--:====~~;---=-Mich ae I J._____ NIH-001052 Subject: GPMB : MESSAGEON BEHALFOF THE CO-CHAIRS:UPDATE MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board members, Thank you to those of you who joined the call on Thursday on short notice. In light of our discussion, we would like to update you on a few matters : (b) (4) • Coronavirus outbreak. We have asked Jeremy Farrar to act as t he Board' s focal point on the COVID-19 outbreak, to represent and advise the Board on the science of the outbreak and the financing of the response. We thank Jeremy for agreeing to take on this role. • Follow -up Board teleconference call. Since many of you were unable to attend Thursday's call, we wish to propose to hold a follow-up Board teleconference call on 4 March at 14 :00 Geneva time . The purpose of the call will be to discuss the coronav irus outbreak, including Jeremy's proposal for Board action on financing. We would appreciate if you could confirm you r participation to Amelie Rioux (b)(6)). A more deta iled agenda and call-in details wi ll be shared shortly. • In-person Board meeting . We wish to confirm that the next in-person Board meeting will take place Tuesday-Wednesday, 5-6 May 2020, in Geneva. The meeting will be an important oppo rtunit y to further discuss strategic issues as well as a draft of the annual report. We will communicate further on logistical detail s. As always, thank you for your support and continued engagement. NIH-001053 With kind regards, Gro and As NIH-001054 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 23:25 :39 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El ;Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia RE: event ru ndown for 3/2 webcast event There is no attachment with this e-mail Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) ~ > From: Lerner, Andre a (NIH/N IAID) [El Date: Sunday, March 1, 2020 6:01 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El ; Folkers, Greg (NIH/NIAID ) [El _______ Cb H_6)>; Conrad, Patricia (NIH/NIAID) [E]________ _ _ )_C_6) Cb --------, .....,....,= Subject: Re: event rundown for 3/2 webcast event Sending th is again as it is for tomorrow. Sent from my iPhone On Feb 28, 2020, at 9:10 PM, Lerner, And rea (NIH/N IAID) [El wrote : --------- Dear Dr. Fauci (and Hilary, if you end up doing this event as ASF' s back-up), NIH-001060 (b)(6) I've attached an "event rundown" for the Harv ard Forum Webcast, which is scheduled from 11:40-lpm on Monday 3/2- a moderated panel discussion. This is a document prepared by the event organizers outlining the run of show, noting what questions the moderator will pose, and some suggested points the organizers thought you might touch on in your answers. Although the organizers prepared this document fo llowing a planning call, they have made it clear that the "talking points" in this document are of course not a script. I have taken their document and highlighted where you appear . I have also added some comments. Let me know what you think. There are no slides for this event. Let me know if you would like to discuss further over the weekend or if you'd like anything for preparation. Sincerely, Andrea Andrea Lerner, MD Medical Officer Office of the Director NIAID/NIH 31 Center Drive, Room 7A10A Bethesda, MD 20892 Cb)(6) cell <2020.3.2-Coronavirus-rundown _tony _AL highlights.docx> NIH-00106 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:53:00 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Proposal to Mitigate Spread of COVID-19 Attachments : Urgent Proposal to Mitigate Spread Fauci.pdf, HCQ,A Modest Proposal for Mitigating COVID-19 2.0.pdf Please take a look and do what you fe el is appropr iate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Alexander Morden MD Date: Sunday, March 1, 2020 2:36 PM ------~= (b)( To: Fauci, Anthony (NIH/NIAID) [E] Subject: Proposal to Mit igate Spread of COVID-19 > (b)(6)> Enclosed is an article I have subm itted which may offer an immediate stra tegy to help infection control in t he general public (and possibly in Oregon & California). NIH-001062 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:52:21 +0000 Tsang, John (NIH/NIAID) [E] (b)( •;Conrad, Patricia (NIH/NIAID) [E) RE: personal Immune baseline and its impact on infection and vaccine ------- responses John: Thanks for yo ur not e. I am copying Cliff Lane here since he and his tea m is in vol ved in a clin ical pro t oco l with COVID-19 pat ient s. He may be abl e to point yo u in the right dir ection. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( (b) < 6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Tsang, John (NIH/NIAID) [E] (b)(6)> Sen t: Sunday, March 1, 2020 2:46 PM -----~ ~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: personal Immune baseline and its impact on infection and vaccine responses Dear Or. Fauci, Hope you are doing well despite the rapidly evolving situation w ith COVID-19 . I wanted to send you a paper we just published last week that you might find relevantattached and a NIAID piece below. please find https://www .niaid .nih.gov/news -events/immune -system-status -predicts -future -responses NIH-001063 Th is paper asks the question of why do ind ividuals mount variab le immune responses to vaccines , infections , and diseases. This extends from our ear lier work on baseline predicto rs of influenza vaccination responses that you hig hlighted as a NIAIO Advance in 2014. A key message is that genetics is often unlikely the answer, but the status of the immu ne system before the pe rt urbation m ay offer clues - here we ident ified such an immune cell circuit involving pOCs-Type I IFNs prior to perturbation in humans and found that its status can predict vaccinat ion and lupus disease activ ities and is temporally stable within individuals for months. (b) (5) Many thanks ! Best w ishes, John. John Tsang,PhD, Senior Investigator I Chief, Multiscale Systems Biology Section, Laboratory of Immune System Biology I Co-Director, Center for Human Immunology (CHI) I National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (.lli.!:i) I emai (b)(6) I off ice: (b)(6) I cell: (b)( )(6) I web : tsang lab I address: (b)(6) 4 Memorial Drive, Bethesda, MD, 20892 USA The information 1nthis e-mail and any of Its attachments 1sconfidential and may contain sensitive nformat1on. It should not be used by ariyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othf?r storag1:>devicPs. National Institute of AIIPrgy and Infectious Diseases shall not accept liability for anystatementsmadethat are sender'sown and not expresslymadeon behaf of the N AIDby one of its representatives. From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Date: Wednesday, December 19, 2018 at 9:43 PM To: "Tsang, John (NIH/NIAID) [E]" (b)(6) Subject: Congratulations John: Congratula tions on being gra nted tenure by the NIH Central Tenure Committee. Keep up your te rrific work. NIH-001064 Well-deserved! Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases B uilding 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001065 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:50:11 +0000 NIAIDODAM FW: Out reach from STAT Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Berke, Rick Date: Sunday, March 1, 2020 10:10 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Outreach from STAT --------- (b)(6) Tony, I know you're swamped but I'm wondering if we could arrange for you this week to take questions from our readers about coronavirus. All of our coronavirus coverage is in front of STAT's paywall and we'd see your contribution as an enormous public service. We would solicit questions for a "live chat" from readers -- and you could pick and choose which ones you want to answer -- and write most of them in advance. Among other leadi ng figures, we 've done this format twice with Nobel winners and it's quite popular . https ://www .statnews .com/events/stat -live-chat -chat-w ith -a-2019-nobel-winn ing-scient ist/ With Helen Branswell, Sharon Begley, Matt Herper , and our whole team, we pride ourselves on covering the coronavirus in the most authoritative and fair-minded way. We've developed a tremendous audience for this coverage. https://www.statnews.com/tag/coronav irus/ Our readers are fairly sophist icated on health and medicine, and we're looking to focus on the health aspects, not the White House polit ics. NIH-001066 In addit ion, I'd be grateful if you 'd consider writing another First Opinion fo r us, maybe on lessons you've learned regarding other outbreaks and how that might be relevant with coronavirus -- or whatever you 'd like. Your vo ice of course is very important and authoritative and we'd be grateful to have it again in STAT. Allbest, Rick Rick BerkeCo -fo under & Exec utiv e Edito r0: (617) 929-7056 M :._(___ STAT (b.;.. .;.. )(.;.. 6j;.io @ ~ ric=k=b=e~r k=e Reporting from the fr ontiers of health and m ed ic in e@st at new s st at ne w s.com fac eboo k .com / stat news SUBSCRI BE TO ST AT PWS for an all-access pass to exclusive stories. SIGN UP HERE for free news letters with the latest in hea lth , biopharma, and science coverage. NIH-001067 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:47:57 +0000 Jeffrey Sachs Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [CJ RE: Might we speak briefly about the coronavirus vaccine development? Jeff: Thanks for th e not e. Happy to chat. Please give my office a call to morr ow AM CbH6) to set up a time w hen we can chat by phone. -------Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu il ding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeffrey Sachs (b)(6) Date: Sunday, March 1, 2020 2:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Might we speak briefly about the coronavirus vaccine development? -------- Dear Tony, Thanks as always for your leadership. Deja vu of our highly productive discussions 20 years ago! Jeff NIH-001068 From: Date: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:46:11 +0000 pascal goldschmidt Sara Sigel;NIAID OD AM Subject: RE: To: ----------- (b)(6) (b)(6) Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail 1 (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: pascal goldschmidt __________ Date: Friday, February 28, 2020 9:00 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Sara Sigel Subj ect : (b_) _ (6J> (b -=")'""' (6) = > (b)(6)> Cb)< Greetings Tony, I know how incredibly busy you are with the coronavirus challenge. I admire so much your cool and effectiveness in the middle of a public health hurricane. (b)(6) With warmest regards, Pascal NIH-001069 Pascal J. Goldschmidt , M.D., Fellow A.C.C ., Fellow A.H .A. President and CEO , Alzady International , LLC. President and CEO , American Healthcare System Ltd. Dean Emeritus, Professor of Medicine Emeritus University of Miami Miller School of Medicine USA AMERICAN HEALTHCARE SYSTEM European Core Global & Alzody lniornotionol NIH-001070 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:44:16 +0000 Silverberg, Kristen RE:question from BRT Kristen: Thanks for the note. Would your companies be able to effectively advocate for improved health care systems in low and middle income countries? Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Silverberg, Kristen Date: Thursday, February 27, 2020 11:40 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: question from BRT ------=--c= CbH6)> -------- Dr. Fauci, I hope you are well. Last February, I moved to Business Roundtable, which represents CEOsof large U.S. companies. Josh is the BRTCEO,and it's been great to work with him again. We wanted to check with yo u on something quickly . Traditionally, BRT has not weighed in on global health security policy, but COVID-19 has served as a reminder that global companies need to be strong advocates for global public health and security. If you had your choice, what would you want to see our companies advocating for, specifical ly? No worries at all if you don't have time to respond. We fully appreciate how important your time is. NIH-00 1071 Best, Kristen NIH-001072 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:32:44 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: ARB therapy in Covid - 19 infection Please respond. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tom Leopold Cb)(6>i> Date: Sunday, March 1, 2020 8:48 AM -------=-=--== (b)((;)> -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: ARB therapy in Covid -19 infection Thank you for responding to my email yesterday about the possibility of ARB therapy in treatment of coronavirus infection. I realize that your research is ongoing. Would you anticipate, however, that the ARB with the most potential role in preventing virus attachment would be the one that has the greatest affinity for the AT2 receptor? Am i correct that losartan is the ARB with the lower receptor (AT1 vs AT2) selectivity and might logically be the most promising ARB to investigate? Thanks . Dr Thomas Leopold Sent from my iPhone NIH-001074 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 22:31:42 +0000 JP Hanke RE: Coronavirus Thank s for the note. CDC is alr eady preparing simi lar public serv ice announcemen t s, which I am sure will find its way to YouTube Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: JP Hanke (b)(6)> Date: Sunday, March 1, 2020 5:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus ------------- ..,.....,...= (b)(6) Dear Dr Fauci, I heard this idea on a radi o interview with Laurie Garrett this morning - how about getting your committee (or one of the government health agencie s) to produ ce a series of short YouTube videos on how to combat the coronavirus: such things as proper handwa shing technique , when to wear a mask , how to ride the subway safely, etc, etc. I think this would be an excellent way to reach the public in the digital age (provided that Mike Pence doesn't try to turn them into campaign ads for Donald Trump), and I strongly urge you to give the strategy serious considerat ion. I know I would watch them and I'm sure millions of other people would too . Sincerely, NIH-001075 Paul Hank e CbH6)VT NIH-001076 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 22:29:32 +0000 Lerner, Andrea (NIH/NIAID) [El RE: Report from 'HHS COVI0-19 Situation Update' call today Thanks. Very helpful. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lerner, Andrea (NIH/N IAID) [E] (b)(6) Date: Sunday, March 1, 2020 4 :06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Eisinger, Robert (NIH/NIAID) (El (b)((;); Conrad, Patricia (NIH/NIAID) (E) (b)(6)> Subject: Report from 'HHS COVID-19 Situation Update' call today -------=-:--:= Passing on some main points from of an "HHS COVI0 -19 Situation Update" call that took place at 3pm today, FYI. • The meat of the call was a situation update by Nancy Messonnier (with epi numbers below). • She noted that the national strategy is still containment . • However, since there are some US locales wit h evidence of community spread, there is considerat ion if some "commun ity level act ion" may be appropr iate, with a move towards a blend of mitigat ion/containment in certain areas. Global epi update: China lab/clinically confirmed cases: 79,824 (+573 in last 24h) China deaths: 2,870 61 international locations with 7,102 cases so far (Armenia, Ecuador, Ireland, Luxembourg new in last 24h) NIH-001077 107 international deaths Widespread community transmission occurring in: China, Iran, Italy, Japan, S. Korea US epi update: 63 confirmed US cases (16 diagnosed here, 3 in Hubei repatriates, 44 in Diamond princess repatriates) 11 presumptive cases (meaning they tested+ at state public health labs, but confirmatory test at CDCis pending) 663 Persons Under Investigation Andrea Lerner, MD Medical Officer Immediate Office of the Director National Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 31 Center Drive, Room 7A10A Bethesda, MD 20892 NIH-001078 To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 22:22:15 +0000 Francis V. Chisari Subject: RE: From: Date: ----------------- (b)(6) Given what is going on with coronavirus, I cannot guarantee that I will be able to attend the Section meeting . I will try my best. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Francis V. Chisari Date: Sunday, March 1, 2020 5:19 PM To: PAUL G AHLQUIST; Zhijian (James) Chen ; Fauci, Anthony (NIH/NIAID) [E) (b)(6J; Michael Oldstone ; Eckard Wimmer Cc: Charles Rice ; Chisari. Francis Subject: (b) (6) Dear colleagues, (b)(6) . Please let me know if you will attend the Section meeting this year and if you're willing to say a few words of support. Best regards, Frank NIH-001079 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:32:36 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: SARS-CoV-19 Please respond Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Peter Panus Date: Sunday, March 1, 2020 10:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: SARS-CoV-19 (b)(6)> -------::-:-,(b)((;)> = Although outside my main area of expertise I have been keeping up with CoVid-19 discussion. One item I have noted is that the disease appears to have a lower incidence in children . The other is t hat the virus appears to at least in part attach through cell membrane angiotensin II type 1 recepto rs. Is the lower incidence of the disease in children possibly due to th is cohort having a higher proportion of angiotensin II type 2 receptors compared to the adult cohort? Sincerely, Peter C. Panus PhD, PT Professor Emeritus Pharmaceutical Sciences Dept. Gatton on College of Pharmacy Sent from Ma il for Windows 10 NIH-001080 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 20:23:14 +0000 NIAIDODAM FW: Invita t ion to speak to the National Economists Club Let us discuss. Unlikely I will have time depend ing on how thi ngs evolve . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Sanchez, Emily Date: Sunday, March 1, 2020 10:35 AM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/N IAID) [El ---------=c:-:-=s (b)( Subject: Invitation to speak to the National Economists Club Dear Dr. Fauci, My name is Emily Sanchez and I am an economist at the American Chemistry Council. I am reaching out to you in my capacity as President of th e National Economists Club (NEC}, which is an organ izat ion of over 1000 government and private sector economists based in DC. The NECholds weekly luncheon events which feature notable experts and economists in Washington. Increasingly, econom ists are being asked to assesst he economic impacts around the incidence and spread of the corona virus as well as the impact of reduced economic activity due to behavioral changes {e.g. people not leaving their homes to work or shop, supply chain disruptions, etc.) . As economists are tasked in assessments, scenario planning and communicating their estimates, accuracy around thei r assumpt ions and understanding of the corona virus and Covid-19 is imperative . We are incredib ly appreciate of the important work and research that the Nationa l Institute of Allergy and Infect ious Diseases provides and we are wondering if you would be willing to speak at one of our luncheons about Covid-19 and the latest developments . NIH-001081 Do you think you might have t ime in your schedule t o spea k to the National Econom ist Club t his month ? We would love to have you speak during the week of March 16-20. Our luncheons typically take place at the Chinatown Garden Restaurant, 618 H St. NW, w ith lunch at noon and your presentation from 12:30 p.m. til 1:30 p.m. Talks are normally on the record and open to the press, unless you request otherwise. Thank you for your consideration. Best regards, Emily Emily Sanchez I American Chemistry Council Director, Economics & Data Analytics Economics & Statistics Department emil y sanchez@americanchemist ry .com 700 2nd Street, NE I Washington, DC I 20002 0: (202) 249-6183 www.americanchem i stry. com ++ +++++++++++++++++++++++++++ This message may contain confidential informat ion and is intended only for the individual named. If you are not the named addressee do not disseminate, distribute or copy this email. Please notify the sender immediately by email if you have received this email by mistake and delete this email from your system. E-mail transmission cannot be guaranteed to be secure or errorfree as information could be intercepted, corrupted, lost, destroyed, arrive late or incomplete, or contain viruses. The sender therefore does not accept liability for any errors or omissions in the contents of this message which arise as a result of email transmission . American Chemistry Council, 700 - 2nd Street NE, Washington, DC 20002, www .americanchem istry .com NIH-001082 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 20:17:45 +0000 Thomas Murray RE: Have you been muzzled? Mr. Murray: Thanks for the note. Please stay silent since I have not been muzzled. I will be on multiple TV shows tomorrow and was on FOXthis AM. No one is censoring me. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=cc-c= From: Thomas Murray Date: Sunday, March 1, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Have you been muzzled? (b)(6) -------- CbH6)> Reference: I'm the nuclear/aerospace engineer who subsequent ly obtained an MPH at the University of Washington since I was working disease transmission within commercial airlines when I was a Boeing employee. And, my undergraduate degree is in chemistry with a minor in microbiology. I've engaged you previously. Hi Dr. Fauci, You've kindly allowed me to engage you, and I'll take advantage of that kindness. The news media is reporting that the White House has muzzled you. Is that true? Before entering the science/engineeri ng world, I was a newspape r city editor in Southern CA (in the 1970s). Therefore, I get and understand the idea of coordinated messaging. (Plus, due to my media background, Boeing used me to help executives prepare for media engagements on challenging topics.) However, if it's true that you are muzzled, then I will initiate a "campaign" with my congressional representatives and the media to NIH-001083 - stop that action. ------------------- (b)( However, before I initiate sucha campaign, will my actionspossibly cause you harm? I recognize tha t you may have backchannels that I may disru pt by engaging. As I related previously, I trust you since you focus on facts and data, you prov ide context for the information that you share, and you avoid emotion in your engagements. I think that residents of the US (and, fran kly the worl d) need your insights regard ing COVID-19. Plus, you're one of the wor ld leaders with regard to infectious diseases. And, if you don't know, you know whom to ask. Please let me know if I should stay silent or become noisy. Thank you. And, t hanks for your service to the US and the world during this very interesting time. Thomas Murray Sent from my iPad NIH-001084 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:13:01 +0000 D.A. Sonneborn RE: News about SARS-CoV-2ad Covid-19 Date: To: Subject: You can tru st CDC. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: D.A. Sonneborn CbH6J> Date: Sunday, March 1, 2020 3:11 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: News about SARS-CoV-2ad Covid-19 ------~~ -------- Cb)( > Dear Dr. Fauci, It would be good to know if you still believe Americans can trust CDC's public -facing authority or whether we'd best look to WHO for reliable information about the virus, the disease and any new mutations which might arise. Mike Pence does not have appropriate credentials . Sincerely, D.A. Sonneborn, Ph.D. (b)(6) NIH-001085 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 20:09:38 +0000 Corey MD, Larry RE:Mike Pence? I am not going to CROI. I am sending in a taped short discu ss ion of NIH research response to COYID-19 Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and infectio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Corey MD, Larry _______ Date: Sunday , March 1, 2020 3:00 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Mike Pence ? ------~~ Cb_)_(_.> ------~~ (b)( · Ah the great communicator of infectious di,ease epidemiology and pathogenesi s. On way back from (b) ( _________________ . News travels fast among the aficionados. We need a POW wow w ith John and Carl on the path to schedule. You coming to CROI '? lfnot 1 could pop down to you. Excuse the I phone typing. On the runway leaving (b) (~ Sent from my iPhone NIH-001086 _, (b)( 4) J will From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:49:51 +0000 Jon LaPook RE: My 11CBSSunday Morning" 5-mi nutes shpiel on coronavirus and COVID-19 To: Subject: Outstanding!! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301 496-4409 (b)(6) E-mail The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Jon LaPook_____ ""' (b"')""" (= Date: Sunday, March 1, 2020 11:27 AM To: Fauci, Anthony (N1H/N1AID)[E] (b)(6) Subject: My "CBS Sunday Morning" 5-minutes shpiel on coronavirns and COVID-19 -------c,-,-c c=,, Tony, Here you go. You can enjoy it in al your spare time. Hope you managed to clear your desk last night. https://vimeo.com/user 10844306 /rev iew/394 766243/cbaS l 43d0d Best, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-00 1089 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:31:54 +0000 Jeffrey V. Ravetch Stelios Bournazos RE: Fe modifications for protective anti-COVID-19 ant ibodies Jeff: Thanks for the note and the slide. Very interesting. preprint when it becomes available. Best, Tony Please send me the Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Jeffrey V. Ravetch Date: Sunday , March 1, 2020 12:43 PM To: Fauci, Anthony (NIH/NIAID) [E]------~~ (b)(6) Cc: Stelios Bournazos (b) (6) Subject: Fe modifications for protective anti -COVID-19 antibodies ----------- ,....;.. __ .:....:....:.::::=====~~ ------------ Dear Tony, I wanted to share a very recent and surprising result we've obtained on the mechanism of antibody protection for anti-viral antibodies. We've previously shown that bNAbs to flu and HIV require FcRengagement for their in vivo potency. Enhancing activating FcR engagement increases the potency of these antibodies by an order of magnitude, on average, and thus are significant contributors to anti-viral protection. NIH-001090 (b) (4) We'll be writing up this story shortly and would be happy to share a pre-print with you . Sincerely, Jeff NIH-001091 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 19:30:12 +0000 Grandi, Paola (b)( RE: ------- Dr. Grandi: (b)(6) Best regards , A.S. Fauci Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Grandi, Paola (b) ( Date: Sunday, March 1, 2020 12:59 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: (b) ( ------~~ Cb _H_6) Dear Dr . Fauci, (b)(6) NIH-00 1092 (b)(6) Please let me know if you would like to discuss this further . I was a former professor at the University of Pittsburgh and now (b) (6) would also be available to discuss. My cell phone is Best Wishes, Paola Grandi PhD M BA (b)(6) NIH-001093 ----- From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 19:22:37 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - " Non-Confidential" Attachments : (O) The Science of Exulta for the Common Cold.pdf, 1) METHODSAND COMPOSITIONSTO INHIBIT SYMPTOMSASSOCIATEDWITH VIRAL UPPERRESPIRATORY TRACT INFECTIONS.pdf Please handl e . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jim Iversen (b)(6) Date: Sunday, March 1, 2020 1:53 PM ------~~ To: Fauci, Anthony ( NI_H.:.. /N_I_A_ID..:. ) .:. [ E..:.).::::::=-~;---(b-) _(6) > Cc: Jacqueline Iversen (b)(6)> Subject: Novel Treatment for Reducing Symptoms Associated with Coronavirus (COVID-19) - "No nConfidential" Dear Dr. Fauci, Sen-Jam Pharmaceutica l has a product under development to reduce the symptoms associated with Uppe r Respiratory Infection (URI). We believe it could provide relief to a large number of people dur ing the COVI0-19 pandemic. Our produc t SJP-002is a combination of an NSAID and a non-sedating antih istamine and does not include a decongestant. Removing the decongestant makes our product ideal for treating the symptoms associated with COVID-19 in pat ients with cardiac conditions who cannot tolerate taking a decongestant. What makes our product novel is that it can be administered early in the treatment phase, thereby reducing the excessive accumulation of inflammat ion, w hich typically results in head congestion, pulmonary congestion, coughing, & sneezing. Our experience has shown that at the 1st signs of experiencing symptoms of URI an indivi dual's symptoms can be drasti cally reduced after ta king our NIH-001094 product twice a day for 3 days. The dramatic reduction in inflammation has the potential to reduce the spreading of the virus by means of cough, sneezing, and spreading of germs through cont act. Current ly, when individuals experience the start of a URI,there is little effective intervention available to change the course of the infection . Individuals delay administer ing pharmaceutical agents, until their congestio n becomes intolerable and excessive. Attached is a copy of our early research and a copy of our non-provisional patent. I share this information with the hope of providing some background for an immediately accessible, safe treatment, alternative to slow the pace and impact of the pandemic . le t me now if we can be of any additional help? Thanks and all the best, Jim seN-JaM ,,_.._ I U C JII Jim Iversen CEO Sen-Jam Pharmaceutical 223 Wall St., #130 Huntin ton , NY 11743 (b)(6) --- ~--c= sen- jam .com Linkedin : llnkedin .com/in/jimiversen NIH-001095 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 19:21:51 +0000 Lawrence 0. Brown, Ph.D. RE: Info re Covid-19 I can assure you that I am not being censo red. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------------~~ -------- From: Lawrence 0. Brown, Ph.D. Date: Sunday, March 1, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Info re Covid-19 (b)(6) Cb)( > Dear Dr. Fauci, Those of us who seek factual, scientifically -based information to the highest degree that it is possible to obtain it will remain hungry and on the alert for whatever complete, up-to -the-moment info rmation that you may have as humanity proceeds deeper into the Covid-19 potential pandemic. We have trusted you through several previous epidemics to provide such information. Therefore, I know I'm not alone in being appalled and frightened by President Trump wanting you to issue info rmation about the current crises only after it has been cleared by his administration. In his off ice as President, Donald Trump may be de facto, Commander-in Chief. There is nothing about his office that confers Expert-in-Chief on him, and what he chooses to say or not say about Covid-19 and its spread should not be treated by the media or anyone as information that is trustworthy for being factual and scientifica lly-based information to the highest degree tha t it is possible to obtain. I hope that you will find it in yourself and in the mission of your office to publicly assure the American public in no uncertain terms that you will not be censored, and that you will honor the public's trust to continue to provide real, research-based information about the frightening health nightmare that all humans are facing in a way that distinguishes us from China's government in its disgraceful and destructive efforts to muzzle those experts who might be able to save lives by merely speaking truth to a population whose health depends on having fact-based, totally un-massaged know ledge as soon as it is available. NIH-001096 It is with our lives, the lives of our families, and the lives that make up our nation that we are count ing on you. Sincerely yours, Lawrence 0 . Brown, Ph.D. Clinical Psychologist/Psychoanalyst (b)(6) (b)(6J NIH-001097 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 16:25 :41 +0000 To: Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Folkers, Greg (NIH/N IAID) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E) Subject: RE: Background briefer Attachments : 20200229_VRCModerna mRNA candidate briefer - with Fauci edits.docx Here it is. From: Marston , Hilary (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 1, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b) ( ; Folkers, Greg (NIH/NIAID) [E] (bH6J>; Masco la, John (NIH/VRC) [E] (bH6J>; Lerner, Andrea (NIH/NIAID ) [E) (b)(6) Subject: Background briefer ------ ..,.....,..-= ASF: Attached please find a proposed background briefer for the visit to the YRC (big thanks to John, Barney, Kizzmekia, the rest of their team and Andrea and Greg). We focused on the VRCitself and the mRNA candidate, figuring tha t the VPOTUSoffice would have a tick tock etc. VRC also prepared ta lking points for the round table should those be requested (I have those if you'd like to see them now, but so far the White House has not asked for this). Available by cell. ----- (b)(6) NIH-001098 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 15:48:15 +0000 Sharon Eblen RE:Thank You Sharon: Many thanks for your kind words. Best regards, Tony -------- (b)(6)> From: Sharon Eblen sent: Sunday, March l, 2020 10:45 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: Thank You (b) ""'(6J => Good Morning Dr. Fauci, I just wanted to say a quick thank you for your recent words to the public. I am a high school physics teacher, and I recognize the importance and the challenges of conveying scientifically accurate informati on to the public. I watched you speak in the two recent press conferences held by t he President, and I appreciated the way in which you communicated difficult information regarding the novel coronavirus. Please keep up the good work during what I'm sure is a very stressful time for you and everyone at the NIH. Sincerely, Sharon M. Eblen NIH-00 1099 From: Date: (b)(6) Sun, 1 Mar 2020 10:34 :15 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: NPR interview request: Or. Fauci To: Subject: Sent from my iPhone Begin forwarded message: From: HJ Mai Date: March 1, 2020 at 10:29:41 AM EST -------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cc: "Billet , Courtney (NIH/NIAID) [E]" Subject: NPR interview request: Dr. Fauci ---------- Dear Dr. Fauci, I'm sorry to bother you on a Sunday, but with t he fi rst coronavirus death of a U.S. patient in Washington state, we are wondering if you would be available for a live interview tomorrow morning our show. We would like to tal k t o you about the significance of the death in Washington and what states can/must do to prevent a widespread outbreak. Kind regards, HJ From: HJ Mai Date: Friday, February 28, 2020 6:54 AM To: Fauci, Ant hony (NIH/NIAID ) [El ':::=====~~ Cc: Billet, Courtney (NIH/NIAID) [El Subject: Re: Confirmat ion of report -------- Thank you for your reply Dr. Fauci. Sent from my iPhone On Feb 27, 2020, at 10:57 PM, Fauci, Anthony (NIH/N IAID) [E) (b) (6), wrote: --------- NIH-001100 This is really not true . It was taken vey much out of context . From: HJ Mai Date: Thursday, February 27, 2020 2:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Confirmation of report _______ _, (b)(6)> Dear Dr . Fauci, This is HJ from NPRagain. I was wondering if you could confirm a NYTreport that says the White House has instructed you not to say anything about the co ronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hmai@npr .org I____ NIH-001 101 Cb > _C_ 6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:39:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit I hope that someone in Building 1 is letting the Secretary's office know that the VP and POTUS are coming to NIH. (b)(6) ---------------~~ (b)(6) ,..;.!:======~~ (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Se nt : Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit --------- Sent from my iPhone Begin forwarded message: From: "Blackburn, Amy (NIH/OD) [El" (b)(6)> Date: February 29, 2020 at 8:16 :21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" CbH >, "Burklow, John {NIH/OD) [E)" (b)( >, "Folkers, Gr_eg :::..:... (N_IH _;/_N_IA _I_ D:)...: [:.... El:... "=~:;----(b-)(-6) Cc: "Daucher, Marybeth (NIH/NIAID) [E)" (b)(6)> Subject: RE: VIP visit ------- ~= --------- Hi Patty, This is just my really rough draft of an agenda. ------------- (b)(5) Just let me know the timing of things . -----Origi naI Message----From: Conrad, Patricia (NIH/NIAID) [E] (b)( > Date: Saturday, February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [E] (b)(6); Blackburn, Amy (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [E] (b)(6) Subject: VIP visit ------~~ -------- NIH-001 102 Per Dr Fauci- for the round table - he is thinking that tomorrow. Sent from my iPhone NIH-001 103 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:12:35 +0000 Bob Franken RE: I'd like to ta lk Bob: Thanks for the note. I look forward to seeing you again soon. Best regards , Tony ----- Origina l Message ----From: Bob Fra nken ------~ (b~)~(6) => Date: Sunday , March 1, 2020 7: 11 AM To: Fauci , Anthony (NTH/NIAID) [E] Subject: Re: I'd like to talk ------ --....-,..-(b)(6) Tony, First of all, thank you for getting back to me, in spite of the fact that you are so busy. Secondly, it's nice to know they're not muzzled, since you are so incredibly good at making science speak so easy to understand for dummies like me . Once the dust settles , I'd live to see you , to pay attention to our long friendship . Meanw hile, best ofluck. Bob Bob Franken ,V\ VW .bobfranken.tv > On Mar 1, 2020, at 6:53 AM, Fauci, Anthony (NlH/NIAlD) [E] Cb)(6)> wrote: > > Bob: > Thanks for tbe note . I hope that all is well with you. I have never been given orders to get approval from the VP's people to speak publicly about coronavirus. Ever since I have been doing this since the Reagan administration, whenever a member of the Executive Branch such as me gets invited and goes on National TV suc h as the Sunday Talk shows, there is always a routine proces s of clearing it with your department (in this case HHS) who then clears it with the White House. This is routine and has been true for the Reagan , Bush '41 , Clinto n, Bush'43, Obama, and oow the Trump administrat ion. Tt is merely a forma lity so that they know what is comi ng out from the executive branch. I have always gotten clearance with very few exceptions over the past 35 years (usually because they do not want you on TV al the same time that the Pre sident is making an importan t announcement). 1 ha ve never been muz zled or told that I could not spea k out publicly about any thing during this administration. > I hope that thi s is he lpful. > Bes t regard s, > Tony > > -----Original Message----> From: Bob Franken-------~ (b-)~(6) => > Date: Saturday, February 29, 2020 6:12 AM > To: Fauci, Anthony (NTH/NIAID) [E]-----~ (b~)(~6) > Subject: I'd like to talk > >Tony, > > 1 know you're busy, but I'd like to have a brief conve rsation with you. --------- NIH-001 104 > I'm now a syndicated political columnist , writing for King Features. You don 't be surprised to hear that my column is described as "an extended middle finger pointed in all directions". > > Notwithstanding tgat , what I'd like to discuss with you is any orders you've received to get approva l from the Vice President's people to speak pub licly about the coronavirus. > > It ca n be on any basis you choose , on the record, or off. On background (knowledgeable sources) , deep background (sources) , whatever. > > May I call you? > > Best, > > Bob > > Bob Franken > www .bobfranken .tv NIH-001105 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:03 :24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Connecting you two Let us d iscuss. _______ .... (b)( '> From: Collins, Francis (NIH/OD) [El Date: Wednesday, Febru ary 26, 20 20 7:59 AM To: M ichael Milken (mm ilken@knowledgeu .com) Cc: Fauci, Antho ny (NIH/ NIAID) [El (bH > Subject: Connecting you two Hi Mike, Thanks for your call on Monday evening . I've reached out to Tony Fauci and he is interested in speaking with you about how your connections with philanthropy and industry might help as we face a major challenge from coronavirus. I'm ccing To ny on this e-mail and his cell pho ne is (b)(6). I've also given him your coordinates. Best, Francis NIH-001 106 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 12:02:07 +0000 Conrad, Patricia (NIH/NIAID) [El RE:VIP visit We can discuss. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Sunday, March 1, 2020 6:58 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Folkers, Greg (NIH/NIAID) [El Subject: Fwd: VIP visit (b) '""' (= 6)> (b)(6) Sent from my iPhone Begin forwarded message: CbH > From: "Blackburn, Amy (NIH/OD) [El" Date: February 29, 2020 at 8:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [El" CbH6J, "Burklow , John (NIH/OD) [El" (b)(6), "Folkers, Greg (NIH/NIAID) [El" (b)(6) Cc: "Daucher, Marybeth (NIH/NIAID) [El" (b)(6) Subject: RE: VIP visit ------- -== Hi Patty, This is just my really rough draft of an agenda. -------------- (b)(5) Just let me know the timing of things. -----Origi na I Message----From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday , February 29, 2020 7:53 PM To: Burklow, John (NIH/OD) [El -----=(b"""' )(= 6J>;Blackburn, Amy (NIH/OD ) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6) Cc: Daucher, Marybeth (NIH/NIAID) [El (b)(6)> Subject: VIP visit ------- Per Dr Fauci- for the round table - ----------------NIH-001 107 (b)(S', (b) (5) -------------------tomorrow. · This will get more fleshed out Sent from my iPhone NIH-001 108 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 12:01:19 +0000 Geller, Robert D. RE:COVID-19 Questions Bob: Thanks for the note. I hope that all is well with you. Use an N95 if you have them available. Transmission is similar to influenza: respiratory droplets and likely a bit more as aerosol than with influenza . People can transmit even when they are asymptomatic . No approved t herapies; however, we are doing clinical trials on 're-purposed" drugs such as remdesivi r (Gilead), Vaccine going into phase 1 trial in about 6 weeks, but w ill no t be ready for at least 1.5 years. Hope that this is helpful. Best regards, tony From: Geller, Robert D. Date: Wednesday, February 26, 2020 1:10 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Questions --------- (b)(6J> Tony Thanks for everything you are saying and doing. I'm writing to ask for the latest. Thanks Bob. What about general care of a patient suspected or confirmed COVID-19. N95 or surgical mask? Any news on how this disease is being transmitted? Anything new on vaccine or treatmen t? This e-m.ail messageand any attached file(s) is intended for the use of the individualor entity 10 which it is addressed and may contain information that is pri,~legcd and confidential. If the reader of this message is not the intended recipient or an agent or employee of the intended entity, you are hereby notified that any dissem i.natio n, d istribution , or copying of this com municati on is strictly prohib ited . If you have received the message in error . please notify th e sen der imm ediately for instruct ions . Than k yo u. NIH-001109 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 11:55:59 +0000 Anderson, Jennifer (NIH/NIAID) [El FW: Opportunity for a Research Position (b)(6) Please take a look and hand le. From: M. Burhan Majeed Rana <1 Date: Thursday, February 27, 2020 9:07 AM -------------- To: Fauci, Anthony {NIH/NIAID) [E] Subj ec t : ------------ ------ (b)( ..,.....,..-= (b)(6) (b)(6) Dear Dr. Fauci, (b)(6) Kindest regards, Rana, M uhammad Burhan Majeed NIH-001 110 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 04:14:20 +0000 Winnie Stachelberg RE: POSTED:Think ing CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS W innie: Thanks for your note . Best regards, Tony From: Winnie Stachelberg Date: Thursday, February 27, 2020 8:02 AM --------, To: Fauci, Anthony (NIH/NIAID) [E] .----..-.= (b)(6) Subject: RE: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony - sending you an email to say thanks for your steady hand at the helm in this current challenge with Coronavirus . You are such an essential part of our government's response to this public health challenge . Please let us know if there's anyth ing we can do at CAP to assist. We plan on hosting an event next week and I'll send you details as they come togethe r. Again, thank you . Winnie From: Winnie Stachelberg Date: Monday, August 19, 2019 10:42 AM Toi (b)(6) Subject: FW: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Tony Thank you so much for participating in CAP's podcast, Thinking CAPearlier t his month . We think the interview turned out very we ll and hope you think so, too . Have a good rest of the month and Labor Day and I hope our paths cross again soon - either in the neighborhood or at work. Winnie From: Steve Bonitatibus Se nt : Thursday, August 15, 2019 11:21 AM To: Posted Products Cc: Kyle Epstein ; Chris Ford ; Daniella NIH-001111 Leger Subject: POSTED:Thinking CAP: Dr. Anthony Fauci: The Global Fight Against HIV/AIDS Daniella sits down with renowned immunologist Dr. Anthony Fauci to discuss how the United States has and can continue to combat the HIV/ AIDS epidemic, both domesticall y and abroad. https://www.americanprog ress .org/issues/hea lthcare/news/20 19/08 /15/473666/ dr-anthonyfauci-global-fight-hiva ids/ For decades , the HIV/AIDS epidemic has been among the most challenging global health issues to contain. Enter Dr. Anthony Fauci , immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. As one of the foremost experts and advocates against the HIV/AIDS epidemic , Dr. Fauci exuded optimism when talking about the progress being made in both global and domestic containment of the disease. He sat down with Daniella for an interview to discuss his work fighting HIV/AIDS and to share his thoughts on the growing , dangerous anti-vaccination movement. Learn more about the podcast here. Daniella Gibbs Leger is the executive vice president for Communications and Strategy at the Center for American Progress. Ed Chung is the vice president for Criminal Justice Reform at the Center. Kyle Epstein is the media relations manager at the Center . Chris Ford is the broadcast coordinator at the Center. NIH-001112 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:13 :25 +0000 Howard Schatz RE:Commiserating Howard: Many thanks for your note. Much appreciated. Best regards, Tony ------------- From: Howard Schatz Date: Thursday, February 27, 2020 8:51 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Commiserating -------- (b)(6J> CbH6J> Tony, Watching the spread of the Coronavirus worldwide(?), I can't help but feel for you, as well as the world's population . It must be both challenging as well frustrating to be unable to control every important "leak" and then watching the consequences. I wou ld think it's also sort of exciting, while also being horrib le, given this is what you've trained for most of your professiona l life. And, I would think that most of your other important works need to be put on hold? Wishing you (and all of us) the best of luck, Howard NIH-001 113 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:02:52 +0000 David Folkenflik RE:Following up I have never been inhibited from interacting with the press. -----Original Message ----From: David Folkenflik Date: Friday, February 28, 2020 7:36 AM To: Fauci , Anthony (NIH/NIAID) [E]...______ Subject: Following up ------~~ Cb _)_C _. 6l Dr Fauci - Tcover media and flow ofinfomiation to public for NPR and am also a host. (You and I once spoke years ago when T covered Johns Hopkins over a science research issue.) You told a colleague the report you couldn't comment on Corona virus was taken out of context. In what way? Tbankyou D David Folkenflik Host and Editor, NPR's On Point Media Correspondent, NPR News 11 W 42nd St 19th Floor New York NY 10036 o) 212.880 .3438 m) (b)( e) dfolkenflik@npr.org Sent from my iPhone NIH-001 114 From: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 04:01 :29 +0000 Andrew Cvon Eschenbach RE: Question Date: To: Subject: Andy: Thanks for the note. l am sure that the Chinese are looking at this, but I have not seen any data in th.is regard, will try to find out if anyone is looking at th.is in the USA patients. Best regards, Tony -----Original Message----From: Andrew C von Eschenbach__________ Date: Friday, February 28, 2020 9:52 AM To: Fauci, Anthony NTH/NIAID) [E]______ (b_~_(6) _, ------~~ (b_H_6J>; Fauci, Anthony (NfH/NIAID) [E] (b)(6) > Subject: Question Tony Does anyone know what the NK cell profile was like in patients who succumbedto Coronavirus? Is there a difference in imm une profile betwe en mild and severe cases? Anyone looking at that? Miss being there at your side in this battle Andy PS Thank you and your team for guiding the Celularity team to get it right. Also you have as always, my utmo st respect for being the "good and faithful servant'' Andrew C. von Eschenbach MD Samaritan Health Init iati ves NIH-001 115 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 03:57 :44 +0000 Strauss, Eric M. RE:500k dead? (Background) To: Subject: That number seems exceptionally high. From: Strauss, Eric M . Se nt : Friday, February 28, 2020 10:34 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: SO0k dead? {Background) ------~~ (b)(6) Hello Dr Fauci: Hope you're holding up well. Remember to rest and hydrate! We had a DHS person tell us epidemiology models for US show worst case scenario 98m get COVID-19 and S0Ok dead . I've seen models all over the board. And Dr Jen and I are keeping our coverage on point on what we know and what we don't know . If that a possible number for our plann ing? Or is that outlandish? Thx. - EMS EricM. Strauss,ABCNews Managing Editor, Medical Unit (b)(6) @ericM strauss NIH-001 116 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:49:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: coronavirus Please take a look and hand le. Thanks. (b)(6) From: William H. Sherman, MD Se nt: Friday, February 28, 2020 11:11 AM ------------ To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: coronavirus William H. Sherman M.D. (b)(6) Anthony Fauci, M.D. (b)(6) Dear Dr. Fauci: I reviewed the publications about the last 2 coronavirus infections. Both MERSand SARSwere severe, short lived problems that have not recurred. One would expect Covir-19 to follow a simi lar path : infect a wide group of susceptible people and then disappear, If that is so, anything that is more than six months away may not be of value-remdisivir or a vaccine. Even if remdisivir works, it will take months to produce sufficient amounts to treat this illness. Has ribavirin been assessed for an ability to slow down the replication of this virus? We do not need to eradicate the virus. Just slowing down the rate of symptoms progression would allow time for the immune system to mount a curative response. Ribivirin is the only approved anti-viral that may have shown some clinical benefit against similar coronavirus infections, but the reports are anecdotal and the benefit short term . It was only administered to a few patients who were already on respirator support, and most still died. If their lungs were already destroyed, eliminating the virus would not change the outcome. There were no studies of treating mild illnesses before they progressed to needing respirator support. If the 50 year old coronavirus patient described in the Lancet had been treated in first week of symptoms, before needing respiratory support, he may have survived . On autopsy, most of his lung had been destroyed . If ribavirin has even marginal benefit, decreasing hospitalization by 10% yields an enormous savings. I do not have accessto the data on this virus and the possible effects of the antivirals that have been evaluated. However, ribavirin has any effect on viral pro liferation, we can write and a randomized trial of ribav irin (b) (4) (b) (4) NIH-001 120 I look forward to hearing from you about the data on ribavirin against this virus and your thought on this clinical study. Sincerely, William H. Sherman , M.D. NIH-001121 Fauci, Anthony (NIH/NIAIO) [El Sun, 1 Mar 2020 03:49:28 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: The Aspen Institute event today From: Date: To: Subject: Let us discuss. From: Sabrina Ma lhi Date: Friday, February 28, 2020 11:14 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: The Aspen Institute event today ------------- -=~ (b)( 6J> Hi Or. Fauci, The whole country is in a panic, could you write on beha lf of the NIH regarding the coronavirus, please? Your vo ice is very impor ta nt on this topic . Thanks, Sabrina On Tue, Feb 11, 2020 at 7:12 PM Fauci, Anthony (NIH/NIAID) [El -------- Sabrina: Many thanks. in mind . It was nice to meet you today. (b) C > wrote: I certainly will keep your offer Best rega rds , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone (b) (6) FAX: (301) 496-4409 (b)( 6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Sabrina Malhi Date: Tuesday, February 11, 2020 2:58 PM NIH-001122 To: Fauci, Anthony (NIH/NIAID) [E] ~..._____ Subject: RE:The Aspen Institute event today Cb _H..... ~> Hi Or . Fauci, It was nice meeting you at the event regarding the coronavirus today at The Aspen Institute. Your expert voice on the virus would be great to have in o ur publication. As I mentioned, I am an opinion editor at The Hill and one of the areas that I focus on is health care. Please let me know if you 'd like to discuss some ideas. I loo k forward to hearing from you! Best, Sabrina Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now smalhi@thehi ll.com. Best, SabrinaMalhi Associate Editor IThe Hill *Please note that my email address is now srnalhi@thehill.com. NIH-001 123 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:24:03 +0000 Gallin, John (OD) [El Date: To: Cc: (b)(6) Subject: RE: Coronavirus vaccine center (b) (5' From: Gall in, John (OD) [El Cb)( > Date: Friday, February 28, 2020 1:52 PM To: Lane, Cliff (NIH/NIAID) [El (b)( -------- ...=>; Davey, Richard (NIH/NIAID) [El (b) (6) > Cc: Fauci, Anthony (NIH/NIAID) [El Subjec t : Fwd: Coronavirus vaccine center (b)(6J> Cliff and Rick (and Tony if you have time) (b) (4) (see My friend Barry Coller is below). Do you know if there is any need for this? Thanks. John Sent from my iPhone Begin forwarded message: From: Barry Coller (b)(6)> Date: February 27, 2020 at 10:34:24 PM EST To: "Gallin, John (OD) [El" (b)(6) Cc: Barry Coller ----------- (b)(6) Subje ct : Coronaviru s vaccin e ce nte r John, I suspect that this is an incredibly busy time for you and the Clinical Center . Tony was fantastic last night. Please let him know that he is my hero! (b) (4) NIH-001 127 (b)(4) If you know of any organizations or companies that are looking for sites to conduct vaccine studies, or if you would like us to collaborate with you to get studies completed more rapidly, please keep us in mind. (bH4J n d .1t Just . ge t s h ar der. I am going crazy writing our ------------ Best regards to Barry (b) (6) NIH-001 128 ~= From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 1 Mar 2020 03:17:42 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Brookings Invit ation Let us disc uss. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 28, 2020 2:26 PM --------- (b)(6)> To: NIAID OD AM Subject: FW: Brookings Invitation Patric ia L. Conrad Public Health Ana ly st and Special Assista nt to the Director National Institute of Allergy an d Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda , Maryland 20892 (b)(6) 301-496-4409 fax Disc laime r: The information in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it fro m your mailbox or any other storage devices. Nationa l Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender"s own and not expressly made on behalf of the NIAID by one of its representatives. From: John Allen Date: Friday, February 28, 2020 2:23 PM To: Fauci, Anthony (NIH/NIAID) [El ------= (b)(6) (bs-.H=6)>; Conrad, Patricia {NIH/NIAID) [El Cc: Lucy Kim Subject: Brookings Invitation Dr. Fauci, Greetings from the Brookings Instit uti on. I'm writing to share the attached invitation for you to speak to our Board of Trustees at th eir annual dinner on Thur sday, March 5 here in Washington, DC. The Brookings Board is a distinguished group of business and community leaders ... I know they would be very eager to hear your thou ghts, especially on the coronavirus crisis given its spr ead into th e U.S. If thi s date does not work with NIH-001129 your sch edul e, we'd be glad to welcome you to Brookin gs at a mor e convenient tim e. I very much appreciate you considering our request, Dr. Fauci! My very best, John R. Allen Pre sid ent Th e Brookings Institution NIH-001130 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 02:58 :01 +0000 Hodes, Richard (NIH/N IA) [E] Cassetti, Cristina (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) RE:SASPand Coronovirus 19 [El Richard: Let me refer the e-mail to Cristina Cassetti who is in charge of the COVID-19 issues in our program. By this email I will ask her to look into this and get back to Jim Kirkland. Best regards , Tony Cr istin a : See my note above to Dr. Hodes. Thanks, To ny ______ _ -----Original Message----,__ From: Hodes, Richard (NIH/NlA) [E] Date: Saturday, February 29, 2020 9:32 PM To: Fauci, Anthony (NIH/NIAlD) [El ______ Subject: FW : SASP and Coronovirus 19 (b)( -------=-::-=, _> Cb _<_· m Tony, Please f~e me for intrudjwu>~our oven¥he lmin g_OJiorities. If ou have a moment to read the emai l below (b) (4) "" B-e-st______________________ _ (b) (4) Thanks for any suggestions. Richard -----Original Message----From: Kirkland, James L., M.D., Ph.D. Date: Saturday, February 29, 2020 8_:5 _8_P _M _____ To: Hodes , Richard (NI H/NIA) [E] ---------- Cc: Sierr a, Felipe (NlH/NIA) [E] (b)( ~~ ------- Subject: SASP and Coronovirus 19 Dear Richard , 1 am sorry to bother you late on a Saturday, but I wanted to let you know that we are finding in as yet unpublished (b) (4) NIH-001133 (b) (4) Jim Sent from my iPad NIH-001 134 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 1 Mar 2020 01:27:44 +0000 Barton Haynes,M.D. Subject: RE: Date: Than.ks, Bart. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: B arton Haynes , M.D. Date: Saturday , February 29 , 2020 8:25 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: RE: (b)(6) --------- (b)( Great job in the press conference today. Tough and high pressure situations it seems . Thanks for being there and representing truth and scie nce ... best b -----Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b)(6) > Date: Saturday, February 29, 2020 7: 14 PM To: Barton Hay nes, M.D. (b)( ; Marovich, Mary (NlH/NIAID) [E] _______ Cb _~_(6) _ > ; Dieffenbach, Carl (NlH/NWD) [E) < (b) (6) > Subject: RE: Impressive! Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It NIH-001 135 should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NI AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message- ---From: Barton Haynes , M.D. (b)( Date: Saturday, February 29, 2020 2:29_ P_M_____ ~~ To: Fauci , Anthon (NIH/NIAJD) [E] (b)( ; Marovich, Mai (b) (6) ; Dieffenbach , Carl (NII-1/NIAID) [E] Subject: FW: __________ --------------=-:=i __,, ---------- Hi Tony, Mary and Carl: Every Saturday am, the DHVI team meets in my office to work on moving the HIV vaccine work forward, and now a new contingent is also working on coronavirus vaccine and new therapeutics. This picture was from 9 am this Saturday morning. Great and dedicated crew listening to the presentation of data! Best bart -----Original Message----From: Barton Haynes , M.D. Date: Saturday , Febrnary 29, 2020 2:25 PM To: (b)(6) Subject: NIH-001 136 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:09:29 +0000 Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Clips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E-mail: The inform ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any stateme nts mad e that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- -----Original Message----From: Routh, Jennifer (NIH/NIAID) (E] (b) ( Date: Saturday , February 29, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet, Courtney (NlH/NlAID) [E] (b)(6) ; Stover , Kathy (NTH/NIAID) [E] ______ ..,.H6) >; Folkers, Greg (NIB/NI AID) [E] Cb (b)(6) ; Conrad , Patricia (NTH/NlAID) [E] Cb)(6)1> Subject: RE: Clips ------~-~ Dr. Fauci - the clips l've been able to pu ll so far are listed below: Hardball (MSNBC last night) : http s://www .msnbc.co m/ hard bal l/ watc h/ dr-anthony -fauci-i-m-not-being-muzzled7965037375 6?c id=sm npd ms tw hb Lou Dobbs (Fox Business last night) : https ://tw itte r.com/Lo uDobbs /stat us/ 1233555383 J9050752 0 Today (NBC this morning ): https:// www .today .com/v ideo/ dr- fauci -on-coronavi rus- fcars-no-nccd-to-changc lifesty le-yet-7968 4677 6 16 Thanks, Jen .Jennifer Routh [E] News and Science Writ ing Branch O ffice of Communications and Government Re lations National Institute of Allergy and Infectio us Diseases (NIAJD) NIH/HHS 31 Center Dri ve Room 7Al 7C Bethesda, Jv(D 20892 Direct: (b) (6) (b)(6) Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive NIH-001141 information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National l nstitute of Allergy and Infectio us Diseases shall not accept liability for any statem ents made that are sender's own and not express ly made on behalf of the NIA TDby one of its representatives. -----Original Message ----From: Fa uci , Anthony (NIH/NJATD) [E] ______ Date: Saturday, February 29, 2020 8:42 AM To: Routh, Jennifer (NIH/NlAI D ) [E] ...--------, Subject: Clips Cb _)_(6J _,> (b .-,)""' (= Jen: This AM I did NBC Today and MSNBC. Please make sure that I get the clips. Thanks Tony NIH-001 142 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:05:03 +0000 Holland, Steven (NIH/NIAID) [E] RE: Human lung m ice Lease the decision up to HHS. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . --------- (b)(6) From: Holland, Steven (NIH/NIAID) [El Date: Saturday, February 29, 2020 11:03 AM To: -..!:=====::;: (b-= )('="= 6):-------------- (b)(6) Fauci, Anthony (NIH/N IAID) [E] Subject: Re: Human lung mice (b)(5) Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b)(6)voice 301-480 -4507 fax Cb)(6) email ------------ Assistant lab: NIH-001143 Assistan t to SD: ~~ (b) (C> f From: ' Date: Saturday, February 29, 2020 at 10:55 AM To: Anthony Fauci Cb)( >, Steven Holland Subject: Human lung mice ------------------------ (b)(6) ---------- (b)(6) Hi Ton and Steve I thoug ht I'd bette r fil l ou in on some recent communications. Dr. (b) (5) (b) (GI NIH-001 144 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:55:28 +0000 (b)(6) To: Subject: RE: in case you need to hear it Mi chael : Thanks fo r t he note. I hope that all is we ll w it h yo u. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Specter (b)(6) Date: Saturday, February 29, 2020 12:39 PM ------ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: in case you need to hear it --.~ CbH > You are one of my very few heroes. And in case you have not seen it, here is my personal love letter to the president (in which you feature semi prominent ly) https://www .newyo rker.com/news/da ily-comment/donald -trumps -ant i-globa list-response -to -a-globalcoronav irus Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell, SMS) ------ (b)(6) NIH-001 145 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 1 Mar 2020 00:53:55 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 Please take a look and respond. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institu tes of Health Bethesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Fred Schaich Date: Saturday, February 29 , 2020 12:55 PM To: Fauci , Anthony (NlH/NlAID) [E] --------= Subject: COVID-19 --------- (b)( · Dear Dr. Fauci, 1'11not be at the CROl this year (b)(6) So 1hope I may be able to ask you a few questions as a concerned citizen. Will we learn: Why there are new cases in the US of unknown origin? Could this virus infect carriers who do not present with :.,ymptoms or present in various levels of very mild infect ion and never get identified as infected? Could individuals host the virus di fferently due to genet ics or ethnici ty? ls this virus consistently sim ilar after multip le generation or is it capable of mutating? Ts the re an ability to develop an antibody immunity through in fect ion? Can one be reinfected? Could the level of infection be detenn ined by the amount of inoculant? Could we leam the level of infect ability of this virus by testing everyone in a given geographic area where there is a deep outbreak? We might also learn about the pathogenesis in a way that we cannot learn otherwise. If this virus is so transmissible could we end up with almost everyone eventually being infected and present with various levels of serious acute infection and death to indistinguishable cases or just carriers? With the clamp /filter on infonnation from this administration, please tell us where we may find regular reports at va1ious levels of current science on what we learn about this virus and vaccine progress, and where we may ask question s? I hope there is place for formal and infonna l community input into treatment , care and vaccine development. Thank you for all your help over the years with your wise perspective through our interviews and leadership at the NIH-001 146 NlH in such a reasonableand responsibleway. Warm regards , Fred Fred Schaich (b)(6) OR NIH-001 147 From: Fauci, Anthony (NIH/ NIAIO) [E) Date: Sun, 1 Mar 2020 00:27:0 4 +0000 To: Cassetti , Cristina (NIH/NIAID) [E] Subject: FW: Coronav iru s - New Idea for treatment & clin ical study Attachments : The Nine Lives of Hydroxychloroquine .docx, Chloroquine & COVID-19 pneumonia.pdf, Remdesivir & Chloroquine Effective lnVitro Against COVID-19.pdf, 6-27-19 (5).jp g Please take a look and respond to them. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------- From: Date: Saturday, February 29, 2020 7:23 PM To: vice.president@whitehouse.gov Cc: Fauci, Anthony {NIH/NIAID) (E] ____ _ >_C6J Cb _ Secretary@HHS.gov ------ (b)(6)> ::;..,...,= (b)(6J>; Redfield, Robert R. (CDC/OD) Subject: Coron avirus - New Idea for treatment & clinical study Importance: High Dear Vice President Pence, We are thankful for your leadership of the Wh ite House Coronavirus Task Force in gathering the latest information about the outbreak, working with doctors and scientists to find solution s, and communicat ing with t he general publi c regarding the situation . We were blessed to meet with you back in August, 2019, when ~ had expressed a desire to meet you . I have attached a picture from our meeting to help you remember . We pray for you often. NIH-001152 Since we are both physicians, we have been following the details of the COVID19 outbreak closely. My husband was researching the anti-viral drug remdesivir this morning, and he came across some articles from Chinese studies that indicated a very well-known drug called hydroxychloroquine {already widely used for 70 years to treat malaria and rheumatological diseases) had very potent activity against COVID-19 infection and pneumonia. This was rather surprising to us, but as we read about the study and the characteristics of hydroxychloroquine, we realized that this could be a very good drug to use for the treatment of high-risk patients infected with COVID-19, who might deteriorate rapidly and progress to hospitalization and need for ICU care. Remdesivir also seems like an excellent anti-viral drug, but it is given intravenously, and is probably reserved for COVID-19 patients who are already entering into severe respiratory distress in the hospital. Hydroxychloroguine, on the other hand, is given orally, and is cheap and readily available. Low doses (6.5 mg/ kg) have been effective in the management of Systemic Lupus Erythematosus and Rheumatoid Arthritis. 200 mg tablets are usually prescribed twice a day with meals; dosage can be increased up to the recommended 6.5 mg/kg if the patient tolerates the lower dose. We wondered if the low dose hydroxychloroquine would be able to be studied quickly in various COVID-19 patients, especially those who are older and / or with medical conditions that put them at higher risk for pneumonia and complications {cardiovascular disease, chronic pulmonary disease, hypertension, diabetes, etc.). In addition, hydroxychloroquine may even be a useful drug to prevent the development of pneumonia in patients diagnosed with COVID-19. Because hydroxychloroquine in an older drug that is generic, current pharmaceutical companies have no incentive to do studies or research on its effectiveness for any new medical conditions. Therefore, the federal government would most likely have to construct and fund the studies. Perhaps Dr. Fauci has already considered this kind of study with hydroxychloroquine. We understand that vaccines are already being studied, and Israel is working on an oral (pill) vaccine. Vaccines take time to go through testing and trials, which is why we are suggesting to you that studies be done on hydroxychloroquine, a readily-available oral drug that could "bridge the gap" to provide some potential NIH-001153 treatment and mitigation of the COVID-19 infections while vaccines are being developed and mass produced. We have attached several articles, which are electronic publications made available in advance (Feb. 4 th & Feb 19th , 2020) of the printed journal publications . We wi ll send a copy of this emai l to Dr. Fauci, Dr. Redfield, and Dr. Azar. Sincerely yours , Drs. Paul & Karyl Stanton (b)( 6) NIH-001154 From: Date: To: Subject: Covid-19 Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 00:14:14 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: One solution in the armoury to protect Health Care Sector Workers against Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Date: Saturday, February 29, 2020 2:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: One solut ion in the armoury to protect Health Care Sector Workers against Covid-19 ------------------------------~~ --------- = Dear Dr Fauci A PPE device, tested and proven at Public Health England Porton Down (PHE), based on innovative technology could be ready to go into production within 20 weeks. It sterilises all airborne pathogens as air is inhaled by the wearer. See www .medi-immun e.com and in part icular the published report on the tests, by clicking on the report under "The Science" The device is due to undergo further tests, at PHE within the next week, specifically against Covid-19. For verification please contact Professor Nigel Silman at PHEPorton Down. Health Services around the world are doing wha t they can to prepare for a significant increase in infections from this highly transmissible virus and if those people in the Health Care Sectors are infected the situation could become untenable. The production of vaccines is under way but no one expects them to be available within the next 12 to 18 months. The Medi-Immune "Protect ivAir ®", which has been under development for some years and could be available within a few mo nths, will give a far greater level of protection than the current masks and respirators and more importantly can remain in use in the future for other emerg ing airborne pathogens - known, unknown or mutating . NIH-001 155 Please take a little time to investigate this option, via the website, or pass it on to those who you believe need to be made aware of it. I will be happy to answer any questions, technical or otherwise, at my emai l address below or on my mobile num ber, also below. Kind regards James Love James Love Director (b)(6) m: t: www .med i-immune .com www .revaxb iotech .com MEDI-IMMUNE Groundbreaking Protec tion & Immunity Medi-Imm une Limited , registered in Eng land and Wales I Company reg istrat ion No: 04554706 1Registered Office : 4 Lady Bank I Tamworth Staffo rdshire I B79 7NB I UK DISCLA IMER: Privileged/COnfidential informat ion and/or Copyright Material may be contained in this email. The informat ion and materia l is intended for the use of the addressee(s ) only . If you are not the addressee or the person responsible for del ivering it to the intended addressee(s) , you may not copy or deliver it to anyone else or use it in any unaut horised manne r. To do so is prohibited and may be unlawful. If you rece ive this ema il by mistake, advise the sender immediate ly by using the reply facility in your emai l softwa re. Any views or opin ions presented are solely those of the author and do not necessarily represent those of MediImmune Lid . Although this email and attachments are believed to be free of any virus or other defects wh ich might affect any computer or IT systems into which they are received, no responsibility is accepted by Medi- Immune Ltd for any loss of damage arising in any way from the receipt or use thereof . NIH-001156 From: Fauci, Anthony (NIH/NIAIO) [El Date: Sun, 1 Mar 2020 00:12:45 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: A sharing on COVID ARDS research Attachments : Dexa_ARDS_COVID-19 for Dr. Tugwell.doc, Tsai 2020_Ann of Intensive Care_ARDS_corticosteroid .pdf Please take a look at this and handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Paul Elias Alexander Date: Saturday, February 29, 2020 2:34 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: A sharing on COVID ARDS research ------------- (b) (6)> ::;.,...,= (b)(6J> Hi Dr. Fauci, I am a trained epidemiologist and expert in evidence based medicine. Particularly in developing clinical practice guidelines and I teach EBM and GRADE methods. You have no idea how much 1 have ad.mired you across the year s, yoW' intelligence and poise. May I ask how I may help you in this matter, this response, I am not talking about money, 1 wish to help, volunteer. I draw your attention to 2 attachments... 1) one is a one page 1 wrote to summarize a meta analysis my team just completed and seeking to publish. It pertains to corticosteroids and ARDS. We are raising that this suggests indirect evidence that we may be able to extrapolate to the COVID patient with severe illness. This within the life threatening issue and emergency and no effective treatment. I share if this can NIH-001 157 help you as I know you are leading this and listened to you today with the president. I support th is p resident fully. 2) I share a paper published today , it on the other hand raises serious questions on the use of corticosteroids in influenza associated ARDS , and one may argue this patient set, is the closes t to the COV ID 19 pat ient. My sense is that the accumulated evidence thus far is weak and argues against corticosteroids. For example, this recently published multicenter retrospective cohort study in medical center ICUs across Ta iwan sought to assess the effect iveness of cort icostero ids in patients presenting w ith influenza-associated ARDS (viro logy -proven ARDS and are on mechanical vent ilation). Researchers examined the impact of early corticosteroid treatment (2:200 mg hydrocortisone equivalent dose within 3 days after ICU admission , determined by a sensitivity analysis) on subseque nt hosp ita l mortality. The study revea led that of the 241 pat ients with in fluenzaassociated ARDS , those rece iving early cort icostero id had a sign ificantly highe r hosp ital mortality rate than those who did not get early corticos teroid [43.5% (37/85) vs. 19.2% (30/ 156), p < 0.001 ). Early corticosteroid treatment was independently associated with increased hospital morta lity in overall patients [an adjus ted OR of 5.02 (95% CI 2 .39- 10 .54), p < 0 .001) and in all examined subgroups . Researchers found that a higher dose and earli er treatment was linked to higher hospital mortality. Moreover, they found that earlier trea tment was related to a significantly increased odds of subsequent bacteremia [an adjusted OR of 2.37 (95% CI 1.015.56)]. These resu lts underscore the urge ncy for robust comparat ive randomized researc h given th is study is based on weake r observat iona l evidence that is confounded by select ion bias and confounded. However this was a stronger study that used statistical adjustment and propensity score matching. Thus this study suggests caution with corticosteroid and thus the importance for caut ion by clin icians as to the potential harms of cort icosteroids in th is po pulat ion . These results , whil e based on weake r methodology , have revea led large estimates of effect, is the stro ngest evidence to date on treatment for ARDS , and brings us closest to the COVID- 19 ARDS patient. Best, Paul E. Alexander, MSc , MHSc, PhD Assistant Professor http://hei .mcmas ter .ca/ McMaster University, 1280 Main Street W, Hamilton, ON L8S 4KI GUIDE Research Methods Group http://guidecanad a.org/ NIH-001158 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:56:39 +0000 Les Gardonyi RE: Suggestion Leslie: Thank you for your note . We are actually looking into the effect of ACE inhibitors on the coronavirus. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Les Gardonyi (b)(6)> Date: Saturday, February 29, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ------~~ Cb _)_C6) _> Subject: Suggestion Dear Mr. Fauci, This may be way too presumptive of a note ... As an engineer I've always liked to und erstand the mechan ics of how things work so I looked into educating myself about the coronavirus and it's mechanics. (b)(6) I've correlated a possible research route for your organization regarding the prevent ion aspect. A quick overlook on this strategy is the follow ing: Coronaviruses are RNA virnses that typically enter human cells when their glycoproteins bind proteins on the cell surface. In the case of the virus that cau ses SARS , that human pro tein is angiotensin-converting enzyme 2 (ACE2). A t this time , scientists think the novel coronavirns is similar enough to SARS that its entry point is likely ACE2 as well. NIH-001 159 source: h ttps: // cen. acs. org/b io Iogical -chemis try/infectio us-disease /novel -corona virus -hi tsChin a/98/web /2020 /0 l Irbesartan is used to treat high blood pressure (hypertens ion) and to help protect the kidneys from damage due to diabetes . Lowering hig h blood pressure helps prevent strokes, heart attacks , and kidney problems . Irb esartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing bloo d vesse ls so that blood can flow more easily. source: https ://www .webmd.com / drugs /2/drug-4720 /irbesartan -oral/ details Idea: Can Irbesartan, being an angiotensin receptor blocker , possib ly help prevent Coronavirus infections ... since the Coronavirus entry to humans is via ACE-2? I share this suggestion with you in the hopes that it may help your department in the research to prevent the spread of the coronavirus ... or to a presumptuous email slated for deletion . Sincerely, -Leslie Gardonyi NIH-001160 From: Date: Sat, 29 Feb 2020 23:54:27 +0000 To: Ellen Butler Subject: RE: Fauci, Anthony (NIH/NIAIO) [E) (b) (6) Ellen: Thank you for your kind note. Very nice family pictures! but in any event, thanks for the note. Best regards , Tony (b)(6) ----- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may c ontain sensit ive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ellen Butler (b) (6) Date: Saturday, February 29, 2020 3:13 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (6) ------~~ -------- (b)(6) I just watched you this afternoon at the press conference. Over the years I have seen you and wondered along with family members if (b)(6l Also I just wanted to say how professional you are and that I don't believe what #45 or his administration have to say regarding the coronavirus but have 100% confidence in what you say and do. Thank you for being the adult in the room. ---------- (b)(6) I am very proud of you . Sincerely, Ellen Butler NIH-001161 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 29 Feb 2020 23:44:17 +0000 Margaret Liu RE: kudos and comment about JAMA Coronavirus article Margaret: Thanks for the note. You make a valid point and I appreciate what you are saying. . On that issue, I have been vocal about making sure that we do not stigmatize Chinese people here in the USA or anywhere in relationship to the COVI0-19 outbreak. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Margaret Liu Date: Saturday, February 29, 2020 3:55 PM To: Fauci, Anthony (NIH/NIAID) [E)r------ --..(b.._.. )= c >; Marston, Hilary (NIH/N IAID) [E] (b)(6)> Cc: Alice Huang ; president@80-20.us Subject: kudos and comment about JAMA Coronavirus article Dear Tony, Wonderful articles in JAMA and NE JM. So glad you are still heading NIAID - it is comforting that there are experts of your caliber still in the room. And thrilled that the NIAID has done so much to develop rapid timelines for DNA vaccines and that you highlighted that progress in the article, since people call me the "Mother of DNA vaccines,". As a former NIAID Council member, I felt I should wr ite to raise an issue that I am sensitized to as a scientist who is ethnically Chinese wh ile American: Why in the JAMA article was it necessary to state that the first travel-related case to the US was a Chinese man (italics mine) w ho had visited Wuhan. Did his being Chinese either ethnically or by citizenship affect anything biologically? NIH-001162 I ask because not only have many Asian people now encountered increased racism in public places (due to fear that any Asian person is a source of COVID-19), but now that the President is turning this epidemic into additional fear-mongering about "borders" it seems all the more important that scientists do not inadvertently add to "xenophobia" (even though non-white skin does not mean a person is foreign) and do not seem to advance any political perspective. Sincerely and with best personal regards, Margaret Margaret A. Liu, MD, DSchc, MDhc, FISV ProTherlmmune & Foreign Adjunct Professor, Karolinska Institute Stockholm, Sweden Adjunct Full Professor , UCSF San Francisco, CA USA President Emeritus, International Society for Vaccines Liu@ProTherimmune.com NIH-001163 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:40:04 +0000 To: Tom Leopold Cc: Subjec t: Cassetti, Cristina (NIH/NIAID) [E] RE:? Al TERNATIVE/SUPPLEMENTALrx for COVID-19: Angiotensin Receptor Blockers l have received this message and we are in fact looking into this. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Buildio g 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institu tes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIALD by one of its representatives. -----Original Message----From: Tom Leopold (b) (6) Date: Saturday, February 29 , 2020 4:24 PM To: Fauci , Anthony (NlH/NlAlD) [E] (b) ( Subject: ? ALTERNATIVE /SUPPL EMEN TAL rx for COVID - 19: Angiotensin Receptor Blockers ----~~= -------~~ Much appreciation for all of your wo rk past and pre sent. I am a cardio logist in New Jersey and whe n I read that the virus attache s to the AT2 receptors in the lungs 1 couldn 't help but think that maybe the class of ARB 's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cell s and prevent or mit igate the severity of infection. Has this approach ever been stud ied and is it wo11h looking into? lma gine if ARBs could lessen the severity of infection how 1eadily available and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you recei ved th is message. Thanks . Dr Thomas Leopold Ema il: (b)(6) Sent from my iPhone NIH-001 164 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:34:59 +0000 Tom Leopold RE:Angiotensin Receptor Blockers: a possible therapy for Covid-19 Than.ksfor the note. We are looking into this possibility. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. lf you have received this e-mail in e1TOr please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----.,...----:.,._.-,. --, From: Tom Leopold (b) ( Date: Saturday, February 29 , 2020 5:01 PM To: Fauci, Anthony (NlH/NlAID) [E] --------= (b)( · Subject: Angiotensin Receptor Blockers: a possible therapy for Covid- l 9 Much appreciation for all of your work past and present. I am a cardiologist in New Jersey and when I read that the virus attaches to the AT2 receptors in the lungs I couldn't help but think that maybe the class of ARB's that we use so frequently for HTN and heart failure management could possibly block entry of virus into cells and prevent or mitigate the severity of infection. Has this approach ever been studied and is it wo11hlooking into? Imagine if ARBs could lessen the severity of infoction how 1eadilyavailable and relatively inexpensive this class of medication is! Would appreciate if someone could get back to infonn me whether you received this message. Thanks. Dr Thomas Leopold Email: (b)(6) Sent from my iPhone NIH-001 165 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 29 Feb 2020 23:29:47 +0000 Richard Goodman RE:Coronavirus question Richard: There are no CDC-issued trave l restrict ions w it hin the USA. The CDC made thi s clear at t he W hit e House press conf erence t his aft ernoon . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Goodman Date: Saturday, February 29, 2020 5:31 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Coronavirus question -------=-,-=, (b)(6) -------- We met many years ago, Tony, ... at an event marking Shelly Wolff's 10 year anniversary at New England Medica l Center. (I had the distinction of being the first medical intern in that program who he reamed out.) My question relates to travel restrictions . The current restr ict ions appear to be quite lim ited, but several organizations, including Google, Amazon, and the HHMI have restricted, or cancelled, even domestic meet ings. As a result of the HHMI cancelation, my own program director indicated his intention to cancel our upcoming Scientific Advisory meeting and, in the non-academic world, (b)(6) (which is ironic since there are more coronavirus infections in my town of (b)(6)Oregon than there are in all of New York). In addition to announcing the new travel restrictions, could you also say something publicly about what doesn't need to be restricted? In part icular, is domestic travel OK, or not? Does the HHMI know something the rest of us don't? Sincerely, Richard Goodman MD PhD NIH-001 166 Vollum Institute Oregon Health & Science University Sent from my iPad NIH-001167 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 23:06:38 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Rapid Collaborat ion for Hand & Nasal Decontamination Formulation Attachment s: NORS-viral review_ V3.pdf, 1998 Reiss NO plays a role in viral infections .pdf, 2005 Akerstrom NO inhibits Corona Viral replication.pdf, 2010 Jung Nitric & SARScorona virus.pdf , 2013 Regev Nitric reduces viral infectivity.pdf, 2015Regev Nitric cattle vs antibiotics BRD.pdf Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Gilly Regev (b)( Se nt: Saturday, February 29, 2020 5:50 PM --------, .....,....,= To: Fauci, Anthony {NIH/NIAID) [E] Cc: Chris Miller (b)( (b)(6) Subject: Fwd: Rapid Collaboration for Hand & Nasal Decontamination Formulation Dear Dr Fauci, Dr Murad sits on our BOD and has suggested t hat we contact you to help expedite a rapid testing of our product on the COVID-19 virus. I know you are probably overwhelmed but hope you might pass this along or suggest a strategy that would be a win-win for us all. We have developed a non-alcohol based formulation that utilizes the nanomolecule nitric oxide (NO). as you know, NO is produced in our body and is our first line of defense against microbes . We have harnessed this in a patented formulation called nitric oxide releasing solution/gel (NORGS).We are focused on the development of products for chronic sinusitis, diabetic foot wounds, warts and toenail fungus. However, internally & personally, we have been using NORGSas an extremely effective natural hand sanitizer and nasal spray to protect ourselves from the common cold and flu for years. There are strong independen t published research that NO is antiviral against Corona viral species. We hae data showing definite virucidal characteristics and moderate antiviral effects in host cells. NIH-001 168 With the recent concern w ith COVID-19, we felt we should try to rapidly test the hand rub and nasal spray against the COVID-19 but need to collaborate with a laboratory that could test this fo r us. Funding collaborators are welcome too, as this was not in our budget but we feel a social responsibility to move this forward . I have included a short white paper of our data and a few articles to support our claims . Feel free to contact me any time (b)(6) ) or have one of your senior staff contact me. Sincerely, Chris Miller and Gilly Regev Gilly Regev, Ph.D. CEO/ Co-founder SaNOtize Research and Development Corp . (b)(6) Phone: emai l (b)(6) htt ps://www .linkedin.com / in/gi lly-regev-694b4a16/ http s://www .sanot ize.com -!::====~~ NIH-001 169 From: Date: To: Subject: (b)(6) Sat, 29 Feb 2020 06:58:29 -0500 Heather DaVia Re:Thank You Joseph and Heathe r: Many thanks for your kind words. Much appreciated. Be st rega rds, Tony > On Feb 28 , 2020, at 8:45 PM, Heather OaVia (b) (6) > wrote: > > Dear Or. Fauci: > > Please accept my personal and heartfelt thanks for your continued efforts to keep the American public informed concerning the coronavims. While listening to you on the radio or at press conferences , your calm, thoughtful, and measured words are very comforting and reassuring. Both your caring response and scientific /medica l expertise are an examp le of the very best in the Federal Government. ---------- > > Again, thank you for your pub lic service and your efforts to keep us as safe as possible. > > Sincerely, > > Joseph P. DaVia (b)(6) > (b)(6) NIH-001170 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 29 Feb 2020 03:15:14 +0000 Tabak , Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El RE:OSTP call Larry : Than ks you ve ry much. Tony From: Tabak, Lawre nce (NIH/OD) [El Date: Friday, Februa ry 28, 2020 8:22 PM ---------- -----~~ To: Fauci, Ant hony (NIH/ NIAID) [E] Cc: Collins, Francis (NIH/OD) [El .;...;.======~ (b)( > (b)(6) (b)( > (b"=' )("=' 6)-Schwe -" tz, Tara (NIH/ OD) [El Subject: OSTP call Tony, Tara and I took the call with Kelvin Droegeme ier, France Cordova (NSF), and Paul Dabbar (DOE). (b) (5) Please let me know if you need anyt hing else. (Tara -if I left anything out please add). Larry NIH-001171 Sent from my iPhone NIH-001172 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 19:48:05 -0500 Harris, Kara (NIH/NIAID) [E];Haskins,Melinda (NIH/NIAID) [E] Fwd: Coronaviruson surfaces Public inq pls Sent from my iPhone Beg in forwarded message: From: Deborah Greene Date: February 28, 2020 at 7:38:44 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{-----Subject: Coronavirus on surfaces (b) (6) (b-H~6J;> Hello Dr Fauci, I am trying to find out how long the coronav irus can remain infect ious on the surface of an object handled by someone with the virus. My concern is with purcha sing items for my jewelry shop that come from China , South Korea, and Turkey. I have no t been able to find anything that addresses this question and hope you can clarify this for me. Thank you. Since rely yours, Deborah Greene Sent from my iPhone NIH-001173 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 23:18:10 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: Corona Virus At t achment s: US Biotest Letter re COVID-19 Fauci, A.pdf, Coronavirus (b)( 4) Rationale.pptx, US Biotest Regulatory History o (b)( 4) pdf, US Biotest COVID-19 ___ Cb _ >_C4 _) References.pdf Please handle . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sens itive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Samant ha Mauro ------------- (b)( 6)> Date: Friday, February 28, 2020 6:11 PM To: Fauci, Anth ony {NIH/NIAID) (E] ;...,;.._.;.__....:..,.:....:..====-~;;----(b)(6) Cc: Gere diZerega Cb H6J> Subject: Corona Virus -------~= ----------- Dear Dr. Fauci: (b)( 4) NIH-001 174 (b) (4) Please contact us if we can be of any help in moving t his potential life-support initiative forwa rd . Sincerely, NIH-001 175 Gere diZerega MD Professor Keck School of Medicine University of Southern California And President and CEO US Biotest, LLC San Luis Obispo, CA (b)( Kathleen Rodgers PhD Professor, Depart men t of Pharmacology College of Medicine Center for Innovation in Brain Sciences Associate Director of Translational Neurosciences University of Arizona Tucson, AZ (b)( NIH-001 176 From: Date: Fri, 28 Feb 2020 16:54:13 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) Subject: Fwd: Urgent Email/Strategy to attack 2019-nCoV coronavirus Attachments : Nucleotide_Analogues_as_lnhibitors of SARS-CoVPolymerase_2_28_2020.pdf, ATT000Ol.htm, Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.pdf, ATT00002.htm Pls handle Sent from my iPhone Begin forwarded message: From: Jingyue Ju Cb)C > Date: February 28, 2020 at 4:46:04 PM ES T To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Barasch, Kimberly (NIH/NIAID) [C]" CbH6J, "direc torsincoming @cdc.gov" , "Redfie ld, Robert R. (CDC /OD)" Cb)(6) ., "Davis , Mindy (NIH/NIAID) [E]" CbH6), "Eakin, Ann (NIH/NIAID) [E]" CbH6) "Stemmy, Erik (NIH/NIAI D) [E]" CbH6J>,"Sciotti, Rick (NIH/N IAID ) [E]" Cb)C6J "Schiltz, Helen (NIH/N IAID) [E]" CbH6J > , "Krafft , Amy (NIH/N IAID) [E]" --------::-:--:-= ~~~ ...... -------=-cc-c= --------- (b)(6) Subject: Re: Urgent Email/Strategy to attack 2019-nCoV coronavirus Dear Dr. Fauci , Following my previous ema il regarding our work on developing strategies to attack the 2019-nCo V coronavirus, I am attaching in this email our experimental results demonstrating that 2 nucleotide analogues are inhibitors of the SARS-Co V polymerase. Since the SARS-Co V polymerase has over 96% similarity to the polymerase from SARS-Co V-2, we expect that the nucleotide analogues, 2 '-F ,MeUTP and 3' -F-dTTP, w ill also inhibit the SARS -CoV -2 polymerase. At this point, it is imperative that the prodrug forms (one is Sofosbuvir that is FDA approved for HepC) of these molecules begin immediate in vitro testing with infected cells (similar to the studies carried out for Remdesivir and chloroquine in the Cell Research article at the link, https :// www.natu r e.com /articles/s41422-02 00282-0 ; PDF file of the article also attached) followed by animal testing trials ASAP. Since we do not have access to the SARS-CoV-2 viral strains, we need your assistance to identify resources at the NIH laboratories to embark on this next step NIH-001177 invest igation ASAP. We can provide the prodrugs to the labs at NIH that you identify for carrying out these studi es. In view of the worldwide SARS-Co V-2 emergency , we'd like yom assistance in getting this off the ground ASAP. I can be reached any time at (b)(6) ----- All the best, Jingyue Ju, Ph .D. Samuel Ruben-Peter G. Viele Professor of Engineering Professor of Chemical Engineering and Pharmacology Director , Cente r for Genome Technology &Biomolecular Engineering Columbia University No rthwe st Corner Building , Room lO0OMl 550 West I 20th Street New York, NY 10027 Phone: -------- (b)(6)>wrote: De ar Drs. Fauci and Redfield, Scientist s in my laboratory at Columbia Un iversity are actively engaged in design strategies to cope with the new strain of corona virus, 20 l 9-nCo V, which has caused a global public health emergency. We have embarked on a project ent itled "Nuc leotide Analogues as Inhibitors of Viral Polymerases". We provide a summary of this work below. Coronaviruses such as the newly discovered virus from Wuhan, China, 2019nCo V , and th e viruses that cause SARS and MERS, have resulted in regional and global public health emergencies. Based on our molecular insight that the hepatitis C virus and the coronavirus use a simil ar viral genome replication mechanism, we reasoned that the FDA-approved drug EPCLUSA (Sofosbuvir /Velpa tasvir) for the treatment of hepatitis C will also inhibit the above coronaviruses, including 2019-nCoV . To develop broad spectrum ant i-viral agents, we fmther describe a novel strategy to design and synthesize viral polymerase inhibitor s, by comb ining the ProTide Prodrug approach used in the development of Sofosbuvir with the use of 3 ' -blockin g groups that we have previously built into nucleotide analogues that function as polymerase terminator s. Please let me know if you would like to receive the full manusc ript. Thank you very much for your consideration . NIH-001178 Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Professo r of Engineering Professor of Chemical Engineering and Pharmacology Director , Center for Genome Technology &Biomolecular Engineering Columbia Univers ity No rthwest Corne r Bui lding, Room l000Ml Phone: NIH-001179 Fauci, Anthony (NIH/NIAIO) [El Fri, 28 Feb 2020 21:27:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus Attachment s: US Biotest Regulatory History of (b)(4) References .pdf , US Biotest Letter re COVID-19 Fauci, A.pdf From: Date: To: Subj ect : ---- (b)(4).pdf, US Biotest COVID-19 Please t ake a look and handle if necessa ry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the o rigi nal intended recipient. If you have re ce ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gere diZerega Date: Friday, February 28, 2020 3:56 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Gere diZerega Subj ect : Corona Virus (b)(6) -------= (b)(6J> =-;__;_ __ .:....;.-=.:===~~--CbH6J> Dear Dr . Fauci: (b)(4) NIH-001 180 (b) (4) Please contact us if we can be of any help in moving this potential life-support initiative forwa rd . Sincerely, Gere G E RE DI Z E R EG A P RE S ID EN T A N D C E O US B lOT ES T, ] NC . 231 BON ETT I DRLVE, SUIT E 240 SAN TEL : LULS OBISPO, CA 93401-73 10 (b)(6) "} FAX : 805.595 . 1350 The information transmitted is intended onlyfor the person or entity to which it is addressedand may contain confidential and/or privilegedmaterial. Any review,retransmission,dissemination or other use of, or taking of any actionin relianceupon, this information by persons or entities other than the intended recipientis prohibited.If you received this in error,please contact the sender and delete the materialf rom any computer. NIH-001181 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:41:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: As bad as measles? Please handl e Begin forwarded message: From: Ed Charlt on (b)(6 )> Date: Februa ry 28, 2020 at l :07:32 PM EST -------~~ To: "Fauci , Anthon y (NIH/N IAID) [E]" Subject: As bad as measles? --------- (b)(6) Dr Fauci, you are the pre-eminent infectious disease physician in the world. I'm concerned the public has lost perspec tive on COVID-19.At this point, it would seem the r0 and CFR are more simila r to rubeo la than they are to Ebo la. Can we rem ind the public of that? Commu nicat ing that influenza will kill more Amer icans than SARS-2 hasn't gained traction. Might someone like yourself or Dr Carson comm unicate more strongly to the public the risk s compared to othe r viruses they are familiar w ith, like rubeola , rubella, varicella, etc? NIH-001182 From: (b)(6) Date: To: Subject: Fri, 28 Feb 2020 13:39:34 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Experimental vaccine for Covid-19 Please respond. M ention risk of enhancement Begin forwarded message: From: "William J. Buikema" Date: February 28, 2020 at l :08:50 PM EST To: "Fauci , Anthon y (NIH/NIAID ) [E]" (b)(6)> -------~~ --------Subject: Experimental vaccine for Covid-19 (b)(6J: Dear Dr. Fauci, I understand the need for the variom stages of testing a new experimentalvaccine, but in listeningto you give a timeline for any new vaccine for the coronavirus, it struck me that perhaps a modified approachmight be considered. Why not allow early use of a vaccine that has passed a phase 1 safety testing, similarto what was done for the Ebola vaccines. If a vaccine is shown to be reasonably safe, why not allow its use it in more at-risk people (elderly , smokers) before phase 2 trials are finished . It could also be helpfu l as with the Ebola vaccines to prevent transmission in hot spots of community acquired infections. There doesn't seem to be much downside compa red to the potential for preventing many more deaths than was seen in the Ebola situation. Sincerely yours, Bill Buikema William J. Buikema, PhD, ResearchAssociate Technical Director, DNASequencing& Genotyping Core University of Chicago, KCBD1230H&I 900 E 57th Street, Chicago, IL 60637 773-702-1088, cancer-seqbase.uchicago.edu NIH-001183 From: Date: (b)(6) To: Subject: Fri, 2 8 Fe b 2020 1 1:21 :22 -0500 Co nr ad , Patr icia (NIH/ NIA ID) [E) Fwd : co ron av irus vacc ine st ory ? Sent from my iPhone Begin forwarded message: From: Olga Khazan Date: February 28, 2020 at 11:09:49 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: coronavirus vaccine story? CbH6>: Hi Tony -- It's Olga at the Atla ntic ... I'm hearing that there's a coronavirus vaccine trial in the works at the VTEU sites. We'd love to tell the story, but everyone is directing me to you and NIA ID. Would you be able to talk with me about this today for a story? My cell is CbH6J,and my desk is 202-266-7387. Thanks, Olga OlgaKhazan Staff Wr iter The Atlantic olga@theatlantic .com cell : (b)(6J NIH-001 184 From: Date: To: Subject: (b)(6) Fri, 28 Feb 2020 08:59 :04 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: MEDIA INQUIRY Sent from my iPhone Begin forwardedmessage: From: Lemonov Alexander Date: February 28, 2020 at 8:13:34 AM EST To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: MEDIA INQUIRY --------=-=--:-= --------- Cb)C6) Dear Dr. Fauci, My name is Alexander Lemonov, I am a producer for RT International TV channel. I would like to invite you to appear on "Worlds Apart", RT's 26-minute uncensored one -on-one interview show . We would like to talk about t he spread of the COVID-19 coronavirus, the response measures countries should take, the world's general preparedness for pandemics, COVID-19's possible consequences for other areas: healthcare, economy, security, etc. Would you be available? FYI: "Worlds Apart" is an uncensored interview show that is aired on RT International, RT America, RT UK, and RT Russia (in Russian). All episodes get featured on RTsocial media accounts, watched by the ir multimillion international crowd . Our guests endorse widely diffe rent views, and we are happy to broadcast different opinions. Here's the link to our show: https://www .rt.com/shows/worlds-apart-oksana-boyko/ "Worlds Apart" has featured: businessman Richard Branson, lawyer Alan Dershowitz, former Israeli FM Tzipi Livni, UN Secretary General Antonio Guterres, UN Women Executive Director Phumzile Mlambo-Ngcuka, former Prime Min ister of Italy Giuliano Amato, former U.S. State Department coordinator for JCPOAJarrett Blanc, foreign minister of Iran Javad Zarif, adviser on international affairs to Supreme Leader of Iran Ali Akbar Velayati, former chief economist of the World Bank Anne Krueger, Secretary General of OSCEThomas Greminger, special adviser to PM of Japan Tomohiko Taniguchi, senior fellow at the Brookings Institution Mike O'Hanlon, etc. I would appreciate a reply. NIH-001 185 Kind regards, Alexander Lemonov Producer 'Worlds A art ", RT Mobile: .._ _____ Cb _H_. 6) Office: +7 (499) 75-000-75, ext. 2492 AlleKcaHAP neMoHoB npoAiocep "Worlds A art", RT Mo6. : (b)(6) Pa6.: +7 (499} 75-000-75, A06. 2492 rt .com twitt er.com /rt com facpbook.com/RTnPw~ youtub e .com/use r/ RussiaToday plus.google .com/102728491 539958 529040/post s CONFIDENTIALITY. The Informationcontained in this transm,ssionIs Intendedexclusively for tho proper use by the Intended addresseesand may contain confidenbaland/or privileged material.Any views expressedin this transmission are those of the individualsender, except where the transmission states otherwise and the senderbeing authorisedappropriately. My review, dissemination and other use of this information, as well as any act ion in reliance upon this info rmation by persons and/or entitles ot he r lh an the intended add ressees ,s prohibited. If you received this information In error, please note lhat no confidentiality or pnv1lege ,s waived or lost by any misstransrn,ssion Note that we monitor e-mails sent or recerved Further co'!lmunicationwill signify your consent to the above. NIH-001 186 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 11:50:04 +0000 Kaplan, Edward H RE: Coronavirus Ed: Thanks for the note. Great to hear from you. I hope that all is well. Best regards , Tony ----- Origina l Message ----From: Kaplan , Edward H (b) (6) Date: Thursday, February 27, 2020 I 0:42 AM To: Fauci, Anthony (NTH/NIAID) [E] Subje ct: RE: Coronaviru:s -------~~ ------ = -,.-.,-,,= (b)(6) > Hi again Tony. Here's a link to a non-technical exp lanation of the paper I shared with you earlier: https:// insights.so m.yale.edu/insights/new -outbrea ks-of-coronavirus-can-bc-halted-,vith-isolation-m easures according -to-study I have seen predictions stating that upward s of 30% of the wor ld's popu lation will be infected , but I don't see this happening. What I do see are lots of local outbreaks from imported cases, some larger than others , but all headin g towards containment. I find Israel to be an interesting test case. A group of infected Korean tourists who visited the country only tested positive for coronavirus after their re turn to Korea, joining the large outbreak that has been reported there. The itinerary of their travel group has been made public so that retrospectively, [sraeli public health officials could ascertain who was exposed where and when (see https://www .hea ltb.gov.il/E nglish/News and Events/Spokesper sons Messages/Page s/23 02202 0 J.aspx). Already 1,600 Israelis have been quarantined on account of possible exposure. It has been twelve days since this group of tourists returned to Korea , and no new infect ions have been reported in Israel associated with this group (there are two Israelis who were infected on the Diamond Princess cruise ship , and one infected while in ltaly). See https://www .ynetn ews.com/artic1e/H l nXPa7E8 . lt will be interesting (and important) to see how many new infections are detected in the days ahead, and if such new infections are found among those already under preventive watch. Nonetheless I totally concur with preparing as if major tran smission will occur. Much better to err by over- rather than under- preparing (a familiar perspect ive from those bygo ne smallpox debates). Finally, a reporter asked me yesterday afternoon what I wanted the Pres ident to say last n.ight. Here was my response : In a sober way summaiize the facts of lhe ou tbreak, state that the US has an excellent preparedness team between CDC and NIH, that at the advice of this team travel restriction s and quarantine measures have already been enact.ed, but as of now the public is at very low risk of infection. Still, citizens should go to cdc.gov now to learn from our experts how to prepare in the event that more extreme measures are needed , stay abreast of the situation here and abroad and follow the advice of our experts , get a flu shot(!), and know that the US has a very strong public health sy stem that can withstand this cha llenge . Anyway,just wanted to share all this with you. Keep up the good work and good luck with the vaccine research, Ed -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci, Anthony (NIH/NIAID) [E] ---------- (b)( NIH-001 187 Subject: Coronavirus containment modeling Dear Dr. Fauci , It has been many years since we corresponded regarding smallpox bioten-orism and vaccinat ion control. The attached paper on containing a commun ity coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can get the transmission rate below epidemic threshold - bur the key is rapid detection of infected persons. Also discussed are some ideas for alleviating congestion in the hospital. ! hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph.D. William N. and Marie A. Beach Professor of Operations Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New Haven, Connecticut 06520 -8200 Phone: e-mai l (b)(6) (b)(6) https://nam05.safelinks.pro tection.outlook.comnu rl=http%3A%2F%2 Ffaculty.som.ya le.edu%2FEdKap lan%2F&am p;data= 02% 7C0 I%7Ce dward.kaplan%40y ale.edu%7Cb00 l l 9dcdbe24bc635d2 08d 7bb9b24c7%7Cdd8c bebb2 l 394d f8b4 114e3e87abeb5c%7C0%7C0% 7C6371841473 15834392&:sdata =l l LC4xAuAc %2BjdNuG%2BA2o GxcS9 LS95PoOR i7yO0dLR d0%3D &reserved=0 NIH-001 188 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 11:25:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus update for your upcom ing Keystone Symposia meeting FYI From: Allison Ogdon Date: Friday, February 28, 2020 12:10 AM To: Allison Ogdon Cc: Heidi Daetwyler Subject: Coronavirus update for your upcoming Keystone Symposia meeting Imp ortance: High KEYSTONE ,ffSYMPOSIA on Molecular and Cellular Biology Accelerating Life Science Discovery Greetings, In light of th e current coronavirus situ at ion, w e would like to provide an updat e on your upcom ing Keyston e Symposia confere nce. The health and safety of our meeting attendees and speakers is our top priority , and we are carefully monitoring the coronavirus situation around the world to ensure we take the necessary precautions as recommended by healthcare providers and public health organizations . Currently, your meet ing will procee d as scheduled, and we will contact you immediately if anyth ing changes. Decisions will be made on a moment to moment basis, as new information becomes available . We assure you that the leadersh ip team at Keystone Symposia is closely monitoring global developments and will take swift action to ensure the health and safety of all meeting participants . As a speaker, you hold a very special role at the meeting as a field leader. We very much appreciate your contribution to both the scientific program, and the community of luminary scientists who w ill convene to direct the future of the field. Your presentation will be a highlight for many attendees, and your insights will inspire others to take on new and innovative directions in their own work . This is the essence of Keystone Symposia -- convening communities of leading scientists to inspire each other to advance biomed icine, and this would not be possible without your engagement . We realize the current situation may add some inconveniences to travel at this time, but we also remind you that each and every one of our speakers is hand-selected by a committee of the world's leading experts to represent their field at the meeting . You are among a very select few to receive this honor. NIH-001189 The meeting organizers, and our team at Keystone Symposia, have put a great deal oftime and effort ov er the last tw o years into designing th e program, and your presentation is a key part of that. We hope you will take these though ts into consideration as the meeting approaches. W hile th is is a t ime we must all be vigilant about publ ic health measures, we are remind ing conference attendees that this is also a t ime to remain calm, rat ional and scient ific in addressing the situatio n. We encourage you to engage w ith your fello w colleagues at the meeting as you normally would, to forge new collaborations and novel ideas that w ill dri ve your research and the field in innovative and fruitfu l di rections . At the meet ing, we are prov iding the follo w ing suggestions based on reco mmendations from t he Nat ional Foundation of Infect ious Disease: • The best way to protect yourself aga inst COVID-19is similar to how you would take precaution s against the cold or flu. Wash your hands of ten using soap and wate r for at least 20 seconds. Cover yo ur cough or sneeze with a t issue or the crook of your elbo w rather than your hands. • There is no need to wear a face mask if you are well and do not have symptoms- masks protect the sick from spread ing germs but wi ll not prevent you from gett ing sick. • Do not assume that anyone of Asian descent is more likely to have coronavirus - do not forget about the importance of inclusivity and evidence-based information. Again, we t hank you for your contributions and commitment to Keystone Symposia and w ish for a very successful and inspiring meet ing. Sincerely, (b)( 6) Debora h L. Johnso n, Ph.D. President and Chief Executive Off icer Keystone Symposia on Molecular and Cellula r Biology KEYSTONE~ SYMPOSIA~ on Molecular and Ce l lular Biology Accelerating Life Science Discovery D I VERS I T Y IN T H E SC IE N TIF IC W O Rl< F OR C E POBox 1630 I Silverthorne I co 80498 I USA (regular mail only) 160 usHighway 6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262 .1230 I 800.253.0685 I www.keystonesympos ia.org Visit virtual.keystonesymposia .orgto view our digital content. NIH-001 190 OC, 0 0 NIH-001191 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 04:25:27 +0000 Kline, Lydia (NIH/OD) [El RE:thank you Lydia: Thanks for your kind note. Best regards, Tony From: Kline, Lydia (NIH/OD) [El CbH6J> Date: Thursday, February 27, 2020 9:45 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: thank you Tony, I'm sure many people are telling you this, but I wanted to add my thanks to you for everyth ing you do to keep the world safer and healthier! You are doing an incredible job (as always) out there with coronavirus. Best, Lydia NIH-001 192 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:23:12 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: inv itation to speak on COVIO19 at the International ATS Conference in May imageOOl.png, image003.png To: Subject: Attachments: Sorry no From: Fennelly, Kevin (NIH/NHLBI) [E]_______ Cb _> _<_ > Date: Thursday, February 27, 2020 9:02 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b"""" )( =6) Subject: invita t ion to speak on COVID 19 at the Inte rnational ATS Conference in May Dear Dr. Fauci, I don't believe that we've formally met, but I have seen you frequent ly on SSEas I admit patients there and often participate in the ward rounds. I am an Al on several of Steve Hollands protocols, and I often help with the drug-res istant TB cases. I have been at the NIH now for over 4 years, although I still fee l like the new guy on the block! Most of my career has been focused on quantifying the infectious aerosols generated by TB patients . I am very involved in the leadership of the American Thoracic Society (ATS) as the Past Chair of the Assembly on Pulmonary Infections and TB. I am writing to invite you to be a keynote speaker at a special Scientific Session being added to our Internat iona l Conference May 16-20 due to the emerging pandemic of COVID-19. The exact time and data are not yet known, but the conference is relatively close in Philadelphia. This would be an opportunity to address and educate global academic leaders in pulmonary and critical medicine, infectious diseases, and public health . We usually have over 15,000 attendees at the ATS meeting. I am attaching the email string below to give you an idea of other speakers being considered. I can only imagine how busy you must be now, so I apologize if this invitation is a distraction or a nuisance. And I would certainly understand if you are unable to jo in us given the demands on your time, but we would be absolutely delighted if you could speak. Please feel to call or contact me at any time with questions or comments. Sincerely, Kevin Fennelly Mobile (b)(6) Kevin P Fennelly, MD, MPH, ATSF Senior Research Clinician Laboratory of Chronic Airway Infect ion Pulmonary Branch Division of Intr amural Research Nationa l Heart, Lung, and Blood Institute (NHLBI) Nationa l Institutes of Health {NIH) NIH-001193 Build ing 10, Room 5-1421 10 Center Drive Bethesda, MD 20892 > Date: Wednesday, February 26, 2020 7:15 PM To: Dela Cruz, Charles (b) ( > Cc: Kristina Crothers (b)(6b; Nahid, Payam (b)(6) ; Saukkone n, Jussi (b)( >; Maria Novozhilova (b)(6); M iriam Rodriguez (b)(6); Fennelly, Kevin (NIH/NHLBI) [E) From: Saukkonen, Jussi J (b)( -!========::::::=:-::;~----- (b)(6) Hicks, Lauri (CDC/0D10/NCEZID/DHQP) (b)(6)>; Yeligar, (b)( 6) McGinniss, John E -----:--:~============~-__:__--2~======--=~----!:==========; (b .:;: ),;;, (6) :::a;> -------------- Subject; Re: Pl-TB Executive Committee Call This looks like a great program . Hope you can get these speakers who will be in demand. On Feb 26, 2020, at 2:44 PM, Dela Cruz, Charles ----------- (b)(6) wrote: Thank you all for your great suggestions ... Here is a possible Agenda for the Special Session on Coronavirus. Ideally, we should have some ATS attendees to be speakers. If anyo ne knows possible candidate, please let us know. I also know that ATS would like to encourage some high profile speakers if possible. Someone from CDC,NIAID, etc. Please let us know additional suggestions. I highlighted bold are possible speakers. We wi ll need to wait until the ATS BOD this week to get t he go ahead to invite the speakers. (b) (4) NIH-001 194 (b) (4) NIH-001 195 (b) (4) Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary, Critical Care and Sleep Medic ine Department of Internal Medicine Department of Microbial Pathogenesis Director , Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone: Cb) (6) FAX: 203 785-5952 Email: Cb)(6) Faculty profile: http://medicine.ya le.edu/ intmed/pulrnonary/people/charles delacruz.profile Lab website: http ://rnedicine.yaJe.edu /la b/delacruz/index.aspx CPIRT website: cpirt.yale.edu (b)(6) From: "Crothers, Kristina" Date: Tuesday , February 25, 2020 at 8:52 PM To: "Saukkonen , Jussi J" Cb)( >, "Nahid, Payam" Cc: "Dela Cruz, Charles' (b)(6) "Saukkonen, Jussi" (b)(6)>, Maria Novozh ilova ------- (b)(6) (b)(6), (b)(6) >, "Kevin P. Fennelly, MD" NIH-001 196 (b) (6)>, (b) (6)> Subject: Re: Pl-TB Executive Committee Call (b) (4) Hi - these are great suggestions. (b) (4) Kristina From: Saukkonen, Jussi J (b)(6) Date: Tuesday, February 25, 2020 9:02 :43 AM To: Nahid, Payam Cc: Dela Cruz, Charles; Saukkonen, Jussi; Crothers, Kristina; Maria Novozhilova; Miriam Rodriguez; (b)(6) · Kevin P. Fennelly, MD; (b)(6J. ; Evans,Scott; Yeligar, Samantha M.; ----------------- (b)(6); McGinniss, John E Subject: Re: Pl-TB Executive Committee Call These would be excellent speakers to also try to get! NIH-001 197 ______ _, wrote: > On Feb 25, 2020, at 11:50 AM, Nahid, Payam (b) (6) > > Agree, these are excellent suggestions.An FYIbelow on what CROIhas assembled for ad hoc session on COVID-19: (b) (4) > > -----------------------------------------------------------------------> Payam Nahid, MD, MPH > Professor of Medicine > University of California, San Francisco > Associate Director, Clinical Trials Operations, UCSFOffice of Research > Medical Director, UCSFCTSITrial s Innovation Network (TIN) > Director, UCSFCenter for Tuberculosis (http :// t b.ucsf.edu ) UCSFCenter for TuberculosisI UCSFCenter for TB tb.ucsf .edu > > Zuckerberg San Francisco General Hospital > Division of Pulmonary & Critical Care Medicine > 1001 Potrero Avenue, Room SKl > San Francisco, CA 94110 > Email: (b) ( > UCSF Profile: htt p:// pro fil es.ucsf .edu/ payam .nahi d PayamNahid I UCSFProfiles profiles. ucsf.edu Payam N_ahid'~ profile, public~tions, research topi~s, an~ co-autho~s ------ > Tel : (b)(6) . > Pronouns: he, him, his NIH-001198 > > > > On 2/25/20, 6:47 AM, "De la Cruz, Charles" > ---------- (b)(6) wrote: > Thank s Jussi for your great suggestions . W e will try to incorporat e these into the final session. > Much appreciated > Charles > > > > > > > > > > > > > > > -----------------------------------------Charles S. Dela Cruz, MD, PhD Associate Professor Section of Pulmonary , Critical Care and Sleep Medicine Departme nt of Internal Medicine Department of Microbial Pathogenesis Director, Center of Pulmonary Infection Research and Treatment (CPIRT) Yale University 300 Cedar Street TAC S441-D New Haven, CT 06513 Phone : (b)(6) FAX: 203 785-5952 > (b)(6) > Email: > Faculty profile: https ://urldefense .proofpo int.com/v2/ur l?u=http 3A med icine.yale.edu intm ed pulmonary peop le charles SFde Iacru z.p rofile&d =Dw IGaQ& c=iO RugZIs2LIYyCAZRB3Xlg & r=Xo HvlYAp U j67iV1KyA lzSg&m=OCAE Xv-43B0vEiVl nTNd--DXvFYATIj FpvUftbD e3o4&s =XbJr53zM ilg0yYn -iXh9t9 vBPfjcNC8h-jRJ2lihVk& e= X CharlesDela Cruz,MD, PhD < Pulmonary, CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine, and specializesin pulmonaryand critical care medicine NIH-001199 and is currently an Associate Professorat Yale Universityin the > Lab website: https ://u rldefe nse.proofpoi nt. com/v2/ur l?u=http 3A med icine .yale .edu lab delacr uz index .aspx&d=DwlGaQ&c= iORugZIs2LIYyCAZRB3XLg&r=Xo Hvl YApUi67iV1KyA l zSg&m =OCAEXv-43BOvEiVlnTNd-DXvFYATl iFpvUf tbDe3o4&s=F7cVz fOPwSt mglz95Y984or0dPHCoEYBNsv iP7GA2g& e= Dela Cruz Lab urldefense.proofpoint.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunologyand virology from Universityof Toronto and Yale. Clinically, he is trained in internal medicine,and specializesin pulmonaryand critical care medicineand is currently an AssistantProfessorat Yale Universityin the > CPIRTwebsite: cp irt .ya le.edu > > > > > On 2/25/20, 9 :34 AM, "Saukkone n, Jussi" _______ _.C.,.b)_(6) .., wrote : > > Grea ,~•'---------------------------- NIH-001200 ~= (b)(4) (b)(4l X FirstUS MERS-CoV CasesUnderscoreNeed for PreparednessI Global Health I JAMA I JAMA Network urldefense.proofpoint.com Confirmation of the first 3 us cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection highlighted the importance of preparedness plans and infection control policies for hospitals and other facilities in dealing with a potentially dangerous infectious disease. (b __~,._, (4) ..... .__________________________ NIH-001201 X 2019 Novel Coronavirus-Im portant Informationfor Cliniciansl Global Health l JAMAl JAMA Network urldefense .proofpoint.com This Viewpoint summarizes the epidemiology and clinical features of 2019-nCoV infection and reviews CDC criteria to guide evaluation and management of patients with possible infection. (b) (4) NIH-001202 (b) (4) > ----- Origi naI Message----From: Dela Cruz, Charles __________ > Date: Monday, February 24, 2020 9:49 PM > To: Crothers,;.__ Krist ina > ______ (b -=-)~ ("=1""' >___________ ---------~~ > (b_) _(6) _, (b)(6)>; ___ Ma ria Novozhi lova c : Miriam Rodrigu (b)(6) ; Saukkonen, Jussi (b)(6) McGinniss, John E (b) (6) > Subject: [EXTERNAL)Re: Pl-TB Executive Committee Call > > Dear colleagues > > Hope all is well . > > As part of ATS 2020 in May, PITB Programming has been requesting to see if there wou ld be a venue for a coronavirus session. > > The ICC chair and ATS was able to seek out a possib le forum for a Special Session on Coronavirus on the Monday Afternoon during ATS. > > > > Payam and I have been d iscussing a possible session title, content and speakers. The session ti t le could be -(b) (4) NIH-001203 (b) (4) > > Many t hank s Charles > > > > > > Charles S. Dela Cruz, MD, PhD Associate Professor Sect ion of Pulmonary, Critical Care and Sleep Medic ine Depa rtment of Internal Medicine Department of Microbial Pathogenesis Director , Cente r of Pulmonary Infection Research and Treatment (CPIRT)Yale University > 300 Cedar Stre et TAC S441-D > New Have n, CT 06513 > Phone: (b) (6) > FAX: 203 785 -5952 > > Email: (b)(6) > Faculty profile: https ://urld efe nse.proofp oint. com/v2/ url?u=ht tps3A nam OS.safe links.protect ion .ou t look .com -3Furl-3Dhttp -253A -252F-252Fmed icine.ya le .edu 252 Fintmed -25 2 Fpu Imo nary-252 Fpeo pie-25 2Fcha rle s-5Fde lacruz. profi le-2 6a m p-3 Bdata -3D02 2 S7C01-25 7Cchar les.de lacruz -2540ya le.edu -25 7C07f 45 f4dbd77 4 f4a3d cc08d7b9 ffcld2 257Cdd8cbebb21394df8 b4114e3 e87a beb5c-257C0-257C0-257C6371823804254 42155 -26a mp3Bsdata -3DQW W L8cDOcYtHaxgi lDZfU7dywm TyCbpPS4bl002Rp Hs-253 D-26amp -3Breserv ed3DO&d= Dw IGaQ&c = iORugZ1s2 LIYyCAZRB3XLg& r=XoHv lYAp Ui6 7iV1 KyA l zSg& m =OCAEXv43 BOvEiVlnTNd-DXvFYATIj FpvUftb De 3o4&s=TVWeA9SztU xTEK8JSyHFc0kt3 CyA rZW DsYQDZPge u EQ&e= NIH-001204 X CharlesDela Cruz, MD, PhD < Pulmonary , CriticalCare and Sleep Medicine urldefense.proofpoint.com Dr. Dela Cruz completed his research training through an MD/PhD program in the area of immunology and virology from University of Toronto and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Associate Professor at Yale University in the > Lab website : https:// url defe nse.proofpo int .com/v2/u rl?u=https 3A nam OS.safelinks.protect ion .ou t look.co m -3Furl-3Dht tp -253A -252F-252 Fmed icine.yale.ed u252Flab-252Fdelacruz-252 Findex.aspx -26amp -38 data -3D02 -257C01-257Ccharles .delacruz2540yale.edu-257C07f45f4d bd774f4 a3dcc08d7 b9ff cld2 257Cdd8c bebb2139 4d f8 b4114 e3 e87a beb5c-257C0-257C0-257C637182380425442155 -26am p3Bsdata-3DaUEJSTgiaCXmTQiuABOKOYrM iqFxdd2HiPhGuq8Psig-253D-26am p-3Breserve d3DO&d=Dw lGaQ&c=iORugZls2LIYyCAZRB3Xl g&r =XoHvlYApUj67iV1KyA l zSg&m=OCAEXv43BOvEiV l nTNd--DXvFYATlj FpvUft bDe3o4&s =s6rn KnYlg iuU r8011 HRKyYFhvJwdc4 t9rmpZzq ixY&e= Dela Cruz Lab urldefense .proof point.com Dr. Dela Cruz completed his research train ing through an MD/PhD program in the area of immunology and virology from University of Toron to and Yale. Clinically, he is trained in internal medicine, and specializes in pulmonary and critical care medicine and is currently an Assistant Professor at Yale University in the > > CPIRT website: cpirt.yale.edu > > NIH-001205 > > On 2/22/20, 7:47 PM, "Crothers, Krist ina" > --------------- (b) (6)wrote: > Hi all - we need to reschedu le the call as bot h Rachel and I will be t raveling t o the ATS board meeting next Wednesday. Please let me and Mar ia know if you could join a call Wednesday March 4 at 4pm eastern instead. > Kristina > > Sent from my iPhone > » On Feb 21, 2020, at 12:20 PM, Mar ia Novozhilova __________ _. (b) (6)> wrote: >> >> » > > > > Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, rep roduce, distr ibute, disseminate or otherwise use this t ransmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of t he message and any attachments. > > > > > > NIH-001206 NIH-001207 8 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E] Fri, 28 Feb 2020 04:21:24 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Spanih meeting RSVPsorry no. From: Jose Alcami Pertejo Date: Thursday, February 27, 2020 10:16 AM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc: Jose Alcami Pertejo Subject: Invitation to Spanih meeting -------- ~= (b)(6)> Dear Dr Fauci , Hope this mail finds you well. We had the opporttmity to meet in Madrid dur ing the R4P meeting. I was the local chair of the Confe rence and had the privi lege of introducing your talk to the plenary. I wou ld like lo invite you as plenary speaker to the meeting of the Spanish AIDS Society (GESIDA) that will take place in Malaga , Spa in next 30th November 2020. GESIDA Congress is the mos t important HIV national meetings in Spain that brings together the full "HIV Community" including clinicians , basic researchers , experts in epidemiology and public hea lth and member from NGOs and patien ts' associa tions. Overall 700 attendees are expected to come to the meeting. We would love to have you as a speaker in the Opening Plenary Sess ion in evening the 30th November. Your challenging articles regarding the strategies to end the HIV epidemic in the United States , will be a great topic to be addressed in such session and an inspiration to Spanish researchers. If you prefer to talk about a different top ic as the co-morbid ities scenar io in HIV infection it will be welcome too. We would be more than happy if you could participate in this meeting . If know your agenda is always full, even more these days with the current Coronavirus outbreak , NIH-001209 but if you could accept this invitation I think this can represent a real boost in the fight against HIV epidem ics in Spain, a field in which the Spanish AIDS Society is strongly committed . It would we wonderful if we can have you as a speaker. Best wishes Jose Alcarni ************************* AVISO LEGAL************************* Este mensaje electr6nico esta dirigido exclusivamente a sus destinatarios, pudiendo contener documentos anexos de caracter privado y confidencial. Si por error ha recibido este mensaje y nose encuentra entre los destinatarios, por favor no use, informe, distribuya, imprima o copie su contenido por ningun medio. Le rogamos lo comunique al remitente y borre completamente el mensaje y sus anexos. El lnstituto de Salud Carlos Ill no asume ningun tipo de responsabilidad legal por el contenido de este mensaje cuando no responda a las funciones atribuidas al remitente del mismo por la normativa vigente. NIH-001210 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:13:52 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: David Rubenstein's invitation to Dr. Fauci To: Subject: I always like to do things with David Rubenstein From: Conrad, Patricia (NIH/NIAID) [El Date: Thursday, February 27, 2020 12:19 PM To: NIAID OD AM Subject: FW: David Rubenstein's invitation to Dr. Fauci (b)(6)> Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mary Brady Date: Wednesday, February 26, 2020 6:07 PM To: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Cc: (b)(6); Judi lrastorza Subject: David Rubenstein's invitation to Dr. Fauci -------- :7'C= Patricia, David Rubenstein asked that we reach out to you in an effort to schedule an Economic Club of Washington event that would feature Dr. Fauci in a conversation with David on COVID-19. It is my understanding that David had a sim ilar interview with Dr. Fauci in the last week or so. Below are several dates from David's calendar for your consideration. Wednesday, April 22 - Breakfast NIH-001211 Tuesday, April 28- Breakfast or lunch Tuesday, May 5 - Breakfast or Lunch Friday, May 15 - Lunch Additionally, I have attached an invitation letter from Mr. Rubenstein to Dr. Fauci for your convenience. The Economic Club has the ability to turn around an event in a relatively short period of time. As you may recall, our events typically take place at breakfast, lunch or dinner, at downtown Washington, D.C. hotels. Events that feature a prominen t world leader, such as Dr. Fauci, generally attract a select audience of over 500 members and guests from among Washington 's business and government leaders, as well as the diplomatic corps. We understand the complexities and constraints of Dr. Fauci's schedule and can be responsive to his needs. If none of the dates above work with Dr. Fauci's schedule, please suggest some that will and we wil l work with David to confirm a date and begin the process. I have copied Judi lrastorza, who I believe you have worked with in the past, and she will coord inate anything you need. Sincerely, Mary Mary C. Brady Executive Director The Economic Club of Washington, D.C. 1601 K Street NW, Suite 210, Washington, DC 20006 I Mobile: mbradv@economicclub.org Office: (202) 481-3260 (b)(6) Our SponsorsI www.EconomjcC1ub.org @TheEconomicClub I LinkedlnI YouTube NIH-001212 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:10:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Invita ti on to join Scientific Advisory Board Please handle. From: Ajay Gupta (b)( > Se nt: Thursday, February 27, 2020 1:04 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Re: Invitation to join Scientific Advisory Board Hi Dr. Fauci, thanks, Ajay --------- From: "Fauci, Anthony (NIH/ NIAID) [E]" 0 at e: Monday, February 17, 2020 at 3:59 AM To: Ajay Gupta (b)(6) (b)(6) Subject: RE: Invitation to join Scientific Advisory Board Thanks for the note . My position in the US Government does not allow me to join such Boards . From: Ajay Gupta (b)(6)> Se nt: Sunday, February 16, 2020 10:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject ; Invitation to join Scientific Advisory Board ------ -------- ::;..,..-,= (b)(6)> Dear Dr. Fauci, By way of this email, I wou ld like to introduce our new biotech company based in California , Celestial Therapeut ics Inc. (b)(4l NIH-0012 13 (b) (4) We wou ld like to extend an invitation to you to join our company's Scientific Advisory Board . Please see attached herewith the executive summary and a slide deck of our company. Thanks and looking forward to hearing from you shortly. Best regards, Ajay Gupta, Ph.D. President, Chairman & CEO Celestial Therapeutics Inc. Tel: (b)(6) NIH-0012 14 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 04:07:36 +0000 Billet, Courtney (NIH/NIAID) [E] FW: lack of preparedness for the coronavirus pandemic Date: To: Subject: FYI. Does this deserve a response. From: Nejat Duzgunes (b) (6) Date: Thursday, February 27, 2020 1:55 PM To: Collins, Francis (NIH/OD) [E] (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------- (b)( Cc: Nejat Duzgunes Subject: lack of preparedness for the coronavirus pandemic Importance: High Dear Dr. Collins and Dr. Fauci, I am sorry to say that our lack of preparedness for the coronavirus pandemic has its roots in the way biomedical research is funded in the United States, as well as in the lack of leadership and vision on the part of NIH and its institutes since the SARScoronavirus outbreak in 2003. I try to expand on these problems in the article below. I would welcome your response to my thesis. Sincerely, Nejat Duzgune~, Ph.D. Professor of Microbiology Department of Biomed ical Sciences Arthur A. Dugoni School of Dentistry University of the Pacific 155 Fifth Street, Room 412 San Francisco, CA 94103 (b)(6) 1111 lJ',;fVl~'-fTYI>J PACIFIC \ r I h "t..ht,,)I 11 , \ nl I)" ~ ,, n 1 lltn11,lr\ The Wuhan Coronavirus(COVID-19):Why there is no cure or vaccine NIH-001215 In their Medical Virology text published in 1994, 0 .0 . White and F.J. Fenner stated "No convincing evidence has yet been obtained to link human coronaviruses with serious disease ..., but they are an important cause of that trivial but annoying disease, the common cold." This generalization changed drastically with the emergence of the severe acute respiratory syndrome coronavirus in 2002-2003 (SARS-CoV), and the National Institutes of Health (NIH) immediately sought the expertise of these two scientists at the time. Now, 17 years later, we still do not have an antiviral medicine or a vaccine against the novel coronavirus that originated in China, now designated as COVID-19 by the World Health Organization (WHO). On February 21, there were 75,567 cases and 2,239 deaths in China; and 1,152 cases outside China, with 8 deaths, according to the DirectorGeneral of the WHO. The two viruses appear to use the same gate (or "receptor") on host cells to infect them. Despite such expected similarities between new and old strains of the viru s, research on coronaviruses has not been a priority for the National Institute of Allergy and Infectious Diseases (NIAID). In the end, all that the Director of NIAID was able offer is "good healthcare" as a remedy for COVID19 infections. The major reason we do not have a cure for coronaviruses is that there has been no coordinated effort by the NIAID to establish long-term research programs focused on coronaviruses . Realizing the insufficient progress in this area, the NIAID announced on February 6 a "Notice of Special Interest to highlight the urgent need for research on the 2019 novel Coronavirus." Grants have indeed been awarded to some scientists since 2003, but such grants are highly competitive, with success rates of applications to NIAID between 14 and 18%, indicating that 82-86% of applicants are unable to obtain funding to carry out research. The time and effort spent on preparing grant applications to NIH are enormous, diverting these precious resources from actual research to what some scientists call "grantsmanship" (essentially, the ability to sell your idea to a review committee!). These "games scientist play" to procure funding are a hindrance to the progress of science. The fact that we do not have a cure or a vaccine against coronaviruses over the past 17 years since the SARS epidemic, attests to this detrimental effect . Development of a vaccine against COVJD-19tis also not straightforward. SARS was probably not considered by NIH to be an important pathogen on which to NIH-001216 spend resources. Even if the biomedical research community had developed a vaccine against coronaviruses, pharmaceutical companies would probably not have considered it a profitable endeavor. Therefore, it is essential for public funds to be used by NIH and the CDCto both discover an effective vaccine and to manufacture it. We need to ensure that long-term projects to develop antivirals and vaccines against coronaviruses and other infectious agents, including tuberculosis and influenza virus, are implemented and fully funded. We need to have a funding system that does not depend on the often unfounded criticism or whims of grant reviewers . Although the current peer review system is touted generally as the best way to allocate funding , it has never been tested scientifically against an alternative. While half of the NIH budget (currently $39 billion) may still be allocated for high-cost projects, including clinical trials , the other half should be awarded for periods of 10 years or longer to established scientists who have a track-record of scientific work, as well as to young scientists who are starting their first independent position . The budgets of these grants would be somewhat limited, but would provide uninterrupted funding and alleviate the stress of competing for renewals every 3-5 years. Scientists opting for these grants will not have to submit extensive grant applications. More importantly , this system will more than double the number of independent investigators . After a 10-12 year period, the scientific productivity (per grant dollar) of scientists on the classical grant system would be compared with that of scientists on long-term funding. After all, the way we choose the mode of science funding should conform to the way science progresses , by experimentation and analysis . NIH-001217 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:05:11 +0000 Robert Durr RE:Covid-19 We will be looking at this. ----------------- From: Robert Durr Date: Thursday, February 27, 2020 2:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 -------- (b)(6) ::;..,..-,= (b)(6 )1> Dr. Fauci, This may be terribly simp listic, but if Covid-19 binds to ACE2 recep tors in host cells, has anyone looked at ACE2 recep tor blockers as potent ially ameliorating disease severity or infectivity? Sincerely, Robert Alan Durr, M.D. NIH-0012 18 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 04:04:26 +0000 HMS-Faculty Affairs Senior Appointments Subject: RE: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6) Date: To: Dear Dr. Cotti: I am very sor ry, but I just do not have time to do this right now. coronav irus issues. Best regards, Tony I am inundated 24/7 with I hope thatyou understand. From: HMS-Faculty Affairs Senior Appointments Date: Thursday , February 27, 2020 1:59 PM To: Fauci>Anthony (NIH/NIAID) [E] ------(b = )- (~6)> Cc: Cott i, Dagmara ; Tekleab, Sarah Subject: Confidential Evaluation Request on behalf of Harvard Medical School Dean George Q. Daley, MD, PhD (b)(6] Dear Dr. Fauci, - Attached is a letter from George Q . Daley, MD, PhD, Dean of the Faculty of Medicine at Harvard University and Caroline Shields Walker Professor of Medicine, requesting your evaluation of H academic accomplishments. The fol lowing materials are also attached: (b)(6) curriculum vitae, an annotated bib liography of(b)(6)'self-selected 10 most significant scholarly works , and the criteria by which 'CbH 6>: qualifications are to be evaluated . Please confirm receipt of this communication and let me know if you will be able to complete an evaluation. When composing your evaluation, please address the questions in Dean Daley's letter . We would greatly appreciate receiving letters of evaluation by Thursday, March 26, 2020. We are grateful for your time and expertise and we apprec iate your conside ration of this request. Warm regards, Dagmara DAGMARACOTT I, PhD NIH-0012 19 Program Director for Academic Affairs Harvard Medical School I Office for Faculty Affairs Gordon Hall, 25 Shattuck Street, Suite 206 I Boston, MA 02115 office : 617.432.6889 I fax: 617.734.4382 I Hours: M-F 8:30am-4:00pm fa.hms.harvard.edu Executive Assistant : Sarah Tekleab Sarah Tekleab@hms.harva rd.edu I office: 617.432 .7438 NIH-001220 From: Date: To: Cc: Subject: This is really not true. Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:57:45 +0000 HJ Mai Billet, Courtney (NIH/NIAID) [El RE: Confirma tion of report It was taken vey much out of context. From: HJ Mai Se nt: Thursday, February 27, 2020 2:09 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Confirmation of report _______ _. (b)(6)> Dear Dr. Fauci, This is HJ from NPR again. I was wondering if you could confirm a NYT report that says the Wh ite House has instructed you not to say anything about the coronavirus outbreak without prior approval. Kind regards, HJ I HJ Mai I Editor, Morning Edition I hma i@npr.org ----- I NIH-001221 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:54:23 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Idea for coronavirus contention NIAID inquiries, Please _______ '> From: Blanco, Luz {NIH/NIAMS) [E] Date: Thursday, Febru ary 27, 2020 2:51 PM To: Collins, Francis (NIH/OD) (E] Cc: Gottesman, Michael {NIH/0D~)-:[~E]:-=====~(b)(6) > (b) ( _. ""'~""'(= >; Fauci, Anthony {NIH/NIAID) [E] (b Subject: Idea for coronavirus contention Importance: High Dears Dr Collins, Dr Gottesman, and Dr. Fauci: I am reaching to you with t his idea that might sound weird but I th ink it might be helpful. I have this idea to reduce the coronavirus infection and spread ing. It is very simple but can get more complex as well. (b)(5) (b)(5 . I do not have the capacity to work or promote these ideas but hope f u IIy you have the power for doing so. Thanks, regards Luz P. Blanco PhD. Staff Scientist SAB, NIAMS, NIH --------------- NIH-001222 Fauci, Anthony (NIH/NIAID) [El Fri, 28 Feb 2020 03:54:22 +0000 To: Cassetti, Cristina (NIH/NIAID) [El (b)( 4) info Subject: FW: Coronavirus: CONFIDENTIAL: Attachment s: image00l.png , 2018_Book_ UnderstandingTheHostl mmuneResp.pdf, Advances in Clinical Chemistry 2018.pdf, BBASR-2016.pdf, Ch-22-francisandtaylor-2017.pdf, chapter-2012.pdf, GSH2005.pdf, HIVclinical trial2015.pdf, HIVclinical trial2017.pdf, macrophages2012.pdf, macrop hages2013 .pdf , NKCELLS2008.pdf, NKCELLS2012.pdf, RBC-HIV paper_2014 .pdf From: Date: Please take a look at this. -----Original Message- ---From: ParikJ1, Purvi_ ________ (b.,... .,... )(=6)> Date: Thursday, Febrnary 27, 2020 10:39 PM To: Fauci, Anthony (NTH/NIAID) [E] Subject: Coronavin.1s: CONFIDENTIAL: ------~~ (b)(6); (b)( 4) info Hi Dr Fauci You must be swampe d with corona virus related correspondence but wanted to pass on some resea rch that may prove helpfu l with coronavirus_ This pham1acist also plans to meet with Trump administration in upcoming weeks . Jt may prove useful. l havent had a chance to dive deeply into the science of it so dont know efficacy but they are preparing a proof concept. Main researcher is Nayan Patel and his email is ________ Cb _ )_(_, 6) Sincererely, Purvi Parikh , M.D., FACP Allcrgy /lmrmmology Attending Physician Clini cal Assistant Profe ssor , Department of Medicine and Department of Pediatrics Division oflnfectious Diseases and Immunolo&'YDivision of Rh eumato logy Allergy and Asthma Associa tes of Murray Hill 212-685-4225 (office numb er) 212-696-5682 (fax) From: Purvi Parikh (b)( Date: Thursday, February 27, 2020 9:43:18 PM To: Parikh, Purvi Subject: Fwd: CONFIDENTIAL: (b) (4) info (EXTERNA L] Sent from my iPhone Begin forwarded message: NIH-001223 From: Heather Pixton (b) (6) Date: Februa 3, 2020 at 12:43:59 PM EST To: ___________ _ Subj ect: FW: Fwd: CONFTDENTTAL: (b)(6) (b) (4) info Hi Purvi, Here is the email from Dr Patel with his research and other relevant PubMed links. The body of the emai l provides an idea of what he has been working on and how he hopes to conu·ibute to the CWTentoutbreak. I would be happy to connect Dr Patel with you (or someone you suggesl) should you find the informa tion provided warrants further inquiry. Warm Regards, Heather Heather Pixton CSO Pharmacology & Compliance r CABODf [bttps://res.cloudinary.com/drasifo1s/image/upload/vl5449 l 0436/ 1130-cedrecfc.elI.jpg) Heather@CabodiCo.com L [https://res.cloudinary.com/drasifo 1s/image/upload/vl5449 l 0436/ l l 30-cedrec/web.ipg) http://www.bestefekt.com ----- (b)(6) From: Heather (b)(6) > Date: Monday , Februar 03, 2020 12:21 PM To: Heather Pixton --------. (b)( ..._--~~ Subject: FW: Fwd: CONFIDENTIAL : (b)( 4) info Sent from Mai l for Window s 10 -_,..,---------(b)( From: Cedrec Sumimoto (b'""" )(6) Tony, Obviously you are swamped and the country is likely safer for it ! I wanted to be sure you were up to date on our efforts re COVID-19. (b)(4 ) (b)(4) We have had discussions with our part ners at BARDAand have had contact with the Wh ite House. (b) (4) In the near future we will have a cocktail of antibodies ready for testing and we would be delighted to work with you and the NIH if that makes sense. If you would like to discuss further, please call my cell (b)(6) at anyti me. ----- Len * *** ** *** **** ******** ***** **** *** ** *** ********* **** **** **** *** ** **** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail, any dissemination , distribution or copying of this email, or any attachment hereto, is strictly prohibited . If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof . Finally, please note that only authorized representatives of Regeneron NIH-001227 Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ******************************************************************** NIH-001228 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 03:42:11 +0000 Phillips, Kyra RE:Confidential Than.ks, Kyra. -----Original Message ----From: Phillips, Kyra Date: Thursday, February 27, 2020 4:33 PM To: Fauci , Anthony (NIH/NIAID) [E] ...______ Subject: Confidential ------~~ = Cb _)_C _. 6l Dear Tony, This note is between long time colleagues. This entire Coronavirus sto1y, and the handling of it, has really escalated into an unexpected journey. [ want you to know how much I have respected you professionally and medically for nearly 20 years. I also wan t you to know that J have appreciated how we have communicated through the years about threats to om world's health and how honest and transparent you have aJways been. l know you are in a unique situation and I want you to know that 1 respec t that and would never put you in a situation with my co1Tes pondence that would j eopard ize you in anyway. With that said, I hope you can keep me informed, off the record if need be, so I ca n continue to cover this story honestly and fairly. With utmost respect, Kyra @KyraPbillips AB C News lnvestigative Correspon dent KyraPhillips.Com (b)(6) NIH-001229 From: Date: To: Cc: Subject: Fauci,Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:16:38 +0000 Alice Park Conrad, Patricia (NIH/NIAID) [E] RE: Time follow up Alice: I am so sorry that I have not gotten back to you. I have been inundated 18 to 19 hours per day. By the t ime I get to e-mail it is late at night. I will try to connect with you tomorrow. Best, Tony From: Alice Park Date: Thursday, February 27, 2020 5:17 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: Re: Time follow up ------~~ -------- (b)(6) Hi -- do you have a few minutes to talk about the following? Happy to chat whenever you're free. Best, Alice On Wed, Feb 26, 2020 at 11:50 AM Alice Park wrote: Hi Dr. Fauci -- have a couple of requests for you, one of which is to speak at our upcoming Time 100 Summit in April -- about COVID-19. I'l l be sending a formal invite but wanted to explore your interest and availability. Also wanted to speak to you about a story I'm work ing on concern ing the risk of community spread of COVID-19 in the US. Wanted to get your perspective on the CDC warning and where those cases might come from. Happy to chat whenever you 're free; I'm relatively free today and this evening. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME 212 522 9830 alice.park@time.com @aliceparkny NIH-001230 From: To: Fauci,Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:49:34 +0000 SuzanneBradley Subject: RE:URGENT Date: There is much misinformation. I actually bave not been muzzled at all by the Vice President. to fly domestically (b) ( ·. -----Original Message----From: Suzanne Bradley Date: Thursday , February 27 , 2020 5:32 PM ---------~~ ---------------~~= To: Fauci, Anthony (NTH/NTAID)[E] Subject: URGENT -------- And BTW, it is safe (b) ( > (b)(6) > Dear Dr. Fauci , J understand Vice President Pence has ordered you to not inform the public about Coronavirus without approval. This is quite terrifying, espec ially since Trump has already shown his desire to spread false or incomplete information about this public healtJ1 crisis. J'm planning to fly dom estica lly TOMORROW -------- Thank you, Suzanne Bradley NIH-001233 (b) ( ·. Is it safe?? From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:46:07 +0000 NIAIDODAM FW: question Let us discuss, but almost certain ly no. (b) (6) > From: Fleisher, Thomas {NIH/CC/DLM) [VJ Se nt : Thursday, February 27, 2020 5:36 PM ~= To: Fauci, Anthony {NIH/NIAID) [E]------(b)(6) Cc: Lang, David ; Kay Whalen ; Rebecca Brandt (AAAAI) Subject: question -------- --------- Tony, As you are acute ly aware , the COVID-19situation is on everyone's mind and accordingly there have been questions raised by members of the AAAAI about what the organization can do to provi de more guidance in this evolving situation. In light of this linked to the fact that our annual meet ing begins March 13 in Philadelphia, we have made the decision to have a 45-60 minute session in the main hall on Saturday (March 14) morning from 7:00-8:00 prior to the scheduled plenary session slated to start at 8:15. My question is whether you would consider taking the Acela up Friday evening returning Saturday morning to host this session w ith a presenta tion followed by a Q&A session. If that is not possible, would you be willing to provide a 10-15 minute (shorter if you deem that appropriate) video generated as close to the 14th as possible that we would have projected in the main hall as noted above . If the latter, would you have a suggestion of an ID person in Philadelphia who would be knowledgeable and could field quest ions following your video . I recognize t hat even if you are willing to come to Philadelphia, that circumstances could arise that would preclude you r traveling in which case we would ask for a video if at all possible . Finally, if neither option is possible, is there somebody in DC (includ ing NIH), Baltimore or Philadelphia who could provide the short review and then sit for 30-45 minutes of Q&A. I am well aware that this is last minute and you have been incredibly busy with issues related to th e pandemic, any help you could provide would be much appreciated by my colleagues and me. Regards, Tom Thomas A. Fleisher, M.D. Scientist Emeritus Department of Laboratory Medicine NIH Clinical Center Bethesda, MD 20892 (b) (6) (tel) 301 -402 -1612 (fax) The contents of this message,together with any attachments, are intended only for the use of the person(s) to wh ich they are addressed and may contain confidentia l and/or privileged information . Further, any medical information herein is confidential and protected by law. It is unlawful for unauthorized persons to NIH-001234 use, review, copy, disclose, or disseminate confidentia l medical information. If you are not the intended recipient, immediately advise the sender and delete this message and any attachments. Any distribution, or copying of this message, or any attachment, is prohibited. NIH-001235 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:43:32 +0000 NIAIDODAM FW: Invita tion to speak at National Academies workshop FMT Vaccines SOT 12.20.pdf Let us discuss. From: Pavlin, Julie Date: Thursday, February 27, 2020 6:04 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIA ID) [El!.=======~ (b..H=6)> Subject: Invitation to speak at Nationa l Academies workshop -------~= Dear Dr. Fauci, It is my pleasure to invite you to present at the National Academies of Sciences, Engineering, and M edicine workshop on "The Critical Public Healt h Value of Vaccines -Tackling Issues of Access and Hesitancy." This workshop will be held on May 28-29, 2020 at the Pan American Healt h Organization (PAHO) headquarters in Washington, DC. The statement of task for the workshop is attached. The 1.5-day workshop will provide a venue to examine the current state of vaccine preventable diseases and the impact of vaccine access and hesitancy on vaccine preventable diseases globally, as well as the multidimensional drivers and impacts of declining vaccine confidence . This workshop wi ll explore health systems, research opportunities , communication strategies, and policies that could be considered to address access, perceptions, att itudes, and behaviors towa rd vaccination. The workshop will be broadcast live over the web to an international audience, and is being hosted by the National Academies' Forum on Microbial Threats . Due to your in-depth expertise in this field, we would like to invite you to give a plenary presentation on the developmentof new vaccinesin the midst of an outbreak, specificallyon the prospects of a coronavirusvaccine.The primary audience for the event w ill be researchers, health practitioners, industry leaders, and policy makers in infectious diseases and global health, so we are looking to initia te this workshop with relevant discussions of barri ers to accessing vaccines. Your responsib ilit ies would be to prepare and del iver a 15-minute presentat ion. We would cover your travel expenses in accordance with U.S. federal government rules. We would be thankful to have your involvement in this workshop. Please let me know if you might be interested. I would be happy to answer any questions you may have. Thank you in advance for your time and considerat io n. We understand that th is is a very busy time and your calendar may be in flux. Best w ishes, Julie Julie A. Pavlin, MD, PhD, MPH Director, Board on Globa l Health Health and Medicine Division - Find us at nationa lacademies .org /HMD The National Academies of Sciences, Engineering, and Medicine NIH-001236 500 Fifth Street, NW Washin gton, DC 20001 Phone: 202-334-2171 Follow Us CIE The National Academi of G · M DIC! -------- ------------------ORGANIZING COMM ITTEE-THE CRITICALPUBLICHEALTHVALUE OF VACCINES-TACKLING ISSUESOF ACCESSAND HESITANCY HEIDI LARSON (Co-Chair), Professor of Anthropology, Risk and Decision Science, London School of Hygiene & Trop ical Medicine MATTHEW ZAHN (Co-Chair), Medical Director , Division of Epidem iology and Assessment, Orange County Health Care Agency KEVIN ANDERSON, Senior Program Manager, Chemical & Biological Defense Division, Science & Technology Directorate, Department of Homeland Security ALISON BUTTENHEIM, Associate Professor, Family and Commun ity Health, School of Nursing, University of Pennsylvania ANDREW CLEMENTS, Deputy Directo r, Pandemic Influenza and Othe r Emerging Threats Unit, USAID AMANDA COHN, Executive Secretariat, Adv isory Comm ittee on Immun izat ion Practices, US Centers for Disease Control and Prevent ion PETER DASZAK, President, EcoHealth Alliance EVA HARRIS, Professor and Director, Division of Infectious Diseases and Vaccino logy, Center for Global Public Health, University of Californ ia, Berkeley ELIZABETH D. HERMSEN, Head, Globa l Antim icrob ial Stewardship , Merck & Co., Inc. NONI MACDONALD, Professor, Department of Pediatrics, Dalhous ie University, Nova Scotia, Canada WALT ORENSTEIN, Professor and Associate Director , Emory Vaccine Center NIH-001237 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 28 Feb 2020 02:42:42 +0000 Jon Cohen Conrad, Patricia (NIH/NIAID) [El RE: Interview request--typo fixed Jon: I am drowning right now. However , I am always happy to speak with you. Cannot do it until I dig out from under. Hopefully, soon. Best, Tony ----- Original Message- ---From: Jon Coh en Date: Thursday, February 27. 2020 5:48 PM To: Fauci, Anthony (NTH/NIAJD) [E] Su~ject: Interview request- -typo fixed ------::-::-:-= (b)( > Dr.Fauci, J was most pleased to bear Sec. Azar 's commitment to "radical transparen cy." 1n that vein, l would like to interview you about COVID-19 for a Science magazine article! am preparing . Thanks in advance, Jon Cohen Science NIH-001238 From: Date: To: Cc: Subject: by White House Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 02:32:50 +0000 Billet, Courtney (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE:Question on report Dr. Fauci told he cannot speak with media unless cleared That is not what I said. I said for SARSthe virus went from bat to civet cat to human; for MERS it went from bat to camel to human. I said we did not know what the animal reservoir was for the jump from animal to human with the nove l coronavirus. Please tell her that. Thanks. -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Thursday, February 27, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E ] ..:.::====== ------~= (b)(6) (b)(6)> (b ~ ~~(6) "" Conrad, Patricia (NIH/NIAID) [E] (b) (6) > Subject: Fwd: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House Q from Donna Young re comments In VP pool report: Do they now know the novel coronavirus jumped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can provide to show that in formation? From: "Young, Donna" Date: Thursday, February 27, 2020 at 7:01:00 PM To: "Billet, Courtney (NIH/NIAID) [E]" < (b)(6) Cc: "Stover , Kathy (NIH/NIAID) [E]" (b)(6) _>, "NIAID NEWS(NIH/NIAID)" , "My les, Renate (NIH/OD) [E]" (b)(6) Subject: Re: Question on report Dr. Faucitold he cannot speak with media unless cleared by White House ------~~ Thank you. Also, can you please clar ify what was in the VP pool report today. Do they now know the novel coronavi rus j umped from a bat to a civet cat [skunk] served at feasts in China and then jumped to humans? Is that the source for certain? Or was he just giving an example? Is there something you can prov ide to show that information? Than k you again. NIH-001239 Donna Young Senior Reporter , Healthcare (Washington , DC) S&P Global News donna .young@sp global.com 301.216 .2433 desk Cb)(6) cell @DonnaYoungDC - 'the pharma diviner' http ://market intelligence .spg loba l.com/our-thinking/news .html -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:55 PM To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) ; Myles, Renate (NIH/OD) [El CbH ; Billet , Courtney (NIH/NIAID) [El Cb)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Can you just attribute to NIAID spox? I ask because he's on meetings and calls ..,, From: "Young, Donna" Date: Thursday, February 27, 2020 at 6:52:48 PM To: "Billet, Courtney (NIH/N IAID) [El" ;-l.======~~ (b)(6), "NIAID NEWS (NIH/NIAID)" Cc: "Stover, Kathy (NIH/NIAID) [El" , "My les, Renate (NIH/OD) [E]" (b)(6)> Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Thank you . Is Dr. Fauci stating it is not tru e? Do I attribute to him or you stating the New York Times report is not true? Thank you for your help. Donna Young Senior Reporter , Healthca re (Washington , DC) S&P Global News donna.young@sp global.com NIH-001240 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://mark etintelligen ce .spg loba l.co m/our-thinking/news .html From: Billet, Courtney (NIH/NIAID) [El Date: Thursday, February 27, 2020 6:39 PM (b)(6) -------- To: Young, Donna Cc: Stover, Kathy (NIH/NIAID) [E] (b)(6)>; NIAID NEWS (NIH/NIAID) < NIAIDNEWS@niaid .nih .gov>; Myles, Renate (NIH/OD) [El (b)( > Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Donna, so sorry, it's been a crazy day. We are not sure exactly where this came from. It's not true. From: "Young, Donna" Date: Thursday, February 27, 2020 at 5:32:22 PM To: "NIAID NEWS (NIH/NIAID)" (b)(6)>, "Stover, Kathy (NIH/NIAID) [E]" (bH6J>, "Myles, Renate (NIH/OD) [El " (NIH/NIAID) [El" (b)(6)>, "Billet, Courtney (b)(6) Subject: Re: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Hi. I'm still waiting for a response on th is. Could you at lest tell me me you are going to respond? Thank you. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.you ng@spglobal .co m 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' NIH-001241 http ://marke ti ntelliqence .s pg loba l.com/our -th i nkinq/news .htm I From: Young, Donna Date: Thursday, February 27, 2020 1:35 PM To: NIAID NEWS (NIH/N IAID) ; Stover, Kathy (NIH/NIAID) [El CbH6J>; Myles, Renate (NIH/OD) [El (b)(6) ; Billet, Courtney (NIH/NIAID) [E] (b)( > Subject: Question on report Dr. Fauci told he cannot speak with media unless cleared by White House Good Day: Could you please comment on this report from the New York Times that Dr. Fauci has been told that he must clear anything he plans to say about the coronavirus outbreak with the White House before he speaks to any media? https://www .nyt imes.com/2020/02/27 /us/ po lit ics/us -coron avi rus -pen ce.htm I "Dr. Anthony S. Fauci, one of the country's leading experts on viruses and the director of the National Institute of Allergy and Infections Diseases, told associates that the White House had instructed him not to say anything else without clearance." Has Dr. Fauci or any other NIH official been told by the White House t hey cannot speak to the media unless cleared by the White House? Please do le t me know. Thank you for your help. Donna Young Senior Reporter , Healthcare (Washington, DC) S&P Global News donna.young@spgloba l.com 301.216.2433 desk (b) (6) cell @DonnaYoungDC - 'the pharma diviner' http://ma rketintelligence .spg loba l.com/our-thinking/news .html NIH-001242 The information contained in this message is intended only for the recipient, and may be a confidential attorney-client communication or may otheiwise be privileged and confidential and protected from disclosure. If the reader of this message is not the intended recipient. or an employee or agent responsible for delivering this message to the intended recipient. please be aware that any dissemination or copying of this communication is strictly prohibited. If you have received this communication in error, please immediately notify us by replying to the message and deleting it from your computer. S&P Global Inc. reserves the right, subject to applicable local law, to monitor, review and process the content of any electronic message or informat ion sent lo or from S&P Global Inc. e-mail addresses without informing the sender or recipient of the message. By sending electronic message or Information to S&P Global Inc. e-mail addresses you, as the sender, are consenting to S&P Global Inc. processing any of your personal data therein . NIH-001243 To: Fauci, Anthony (NIH/ NIAIO) [E) Fri, 28 Feb 2020 00:4 7:19 +0000 Mar k Zuckerberg Subject: RE: From: Date: Mark: Thanks for the note . If we start in April ( ~6-7 weeks from now ) with a phase 1 trial of 45 subjects, it will take another 3-4 months to determ ine safety and some immunogenicity . The next step is phase 2 for efficacy . We may need help with resources for the phase 2 tria l if we do not get our requested budget supplement. I believe that we will be OK. If thi s goes off track, I will contact you. Many thanks for t he offer . Much app reciated . Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mar k Zuckerberg Cb)(6) Date: Thur sday, Febru ary 27, 2020 7: 16 PM ------~= To: Fauci, Anth ony (NIH/ NIAID) [E] Subject: _______ _. (b)(6)> Tony : I was glad to hear your statement that the covid -19 vaccine w ill be ready for human trials in six weeks. Are there any resources o ur found ation can help provide to pot ent ially acceler ate t his or at least make sure it stays on track ? Mark NIH-001245 From: Date: (b)(6) To: Subject: Thu, 27 Feb 2020 17:43:18 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Or. Fauci--Coronavirus comment 3/2 Healthline MEDIA Sent from my iPhone Begin forwarded message: From: Kristen Fischer Date: February 27, 2020 at 5:20:21 PM EST Cb)( To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= CbH6) Subject: Dr. Fauci--C oronavirus comment 3/2 Healthlin e ME DIA Hi there, I'm writing for Healthline abou t coronavirus and how the virus spread may be differen t in the Southern Hemisphere (they mention that in the story below). Care to weigh in? I'd love to know : I. W ill coro naviru s be any less severe in the Sout hern Hemisp here due to the summe r weather there at the moment? 2. W ill the virus spread in No rth America slow down due to geog raph y or wam1er weather at all? What can we expect in 3 months --and in one year as far as coronav irus in the U.S .? 3. Will it differ in how it spreads /tapers off in As ia, due to proximity of the outbreak? 4. Will this event ually be gone or will it be som ething that is a new health threat that could return in a year or so? 5. Any insight inl'o the outlook of coronavir us, how it will sprea d or how long it will be active? Lookin g for a brief email response by Monda y morn ing at 10a.m. Let me know if you can assist ! Warmly, Kris ten Fischer Kristen Fischer v,rww . kristenfischer .com (b) (6j Find your family fun at the Jersey Sbore --get yourfree weekly e-news letter today! See your produ ct or serv ice Re-viewed by Kr isten Fisc her NIH-001246 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 16:29:44 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Covid-19--Conference Call Invitation Let us di scuss. Likely do not have tim e fo r t his. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Buono, Lucia On Behalf Of Gopinath, Gita Date: Wednesday, February 26, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Gopinath, Gita ; Milesi -Ferretti, Gian Maria ; Celasun, Oya <0Celasun@imf .org>; Nabar, Malhar Shyam ; Christiansen, Lone Engbo ; Buono, Lucia Subject: Covid- 19--Conference Call Invitation -------::-::-=, On behalf of Ms. Gopinath: Dear Professor Fauci: We are contacting you in the context of the evolving spread of Covid-19, which is already impacting livelihoods and economic activity in several countries. As you may know, the IMF publ ishes forecasts of economic growth for member countries four ti mes a year, as we ll as macroeconomic pol icy recommendations. In that context, it would be invaluable for us to hear public health experts' views on the likely trajectory of the virus-the number of people that are likely to get infected in different countries and the likely time path. We would also benefit from heari ng experts' views on the optimal public health policy response in different types of countries (countries w ith stronger or weaker health systems, different development levels, etc.), and the implied resource needs. We are planning to set up a conference call with several experts to discuss these issues and were wondering if you would be available to join us. If you would be interested in joining, would you be able NIH-001247 to let my assistant Lucia Buono (lbuono@imf.org ) know of some dates and times that would work for you this week or early next week? We would be extremely grateful for any guidance you might be able to offer as we strive to do our part in helping member countries respond to the epidemic. Best regards, Gita Gopinath Economic Counsellor and Director Research Department International Monetary Fund NIH-001248 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 13:31:19 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (N IH/NIAID) [C] FW: The global health leaders call, Wednesday 4 March at 13:00 CET (b)(4) Swisscom Call code.pdf To: Subject: Attachment s: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6b From: RYAN, Michael J. Date: Thursday, February 27, 2020 7:55 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------ (b)(6); Jeremy Farrar (b) (6); Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) (b) (6); President I Resolve to Save Lives (b)(6) ------------ Tarik Mohammed Cc: SHOC ; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6h; MAHJOUR, Jaouad (b)( ; FALL, lbrahima Soce CbH >; GREIN, Thomas (b)(6) M INHAS, Raman (b)(6); COX, Paul Michael (b)( >; AL-SHORBAJI,Farah (b)(6) _>; POOLE, Marcia (b)(6); DRURY,Patrick Anthony CbH ; GRAAFF, Peter Jan ____ _ )_C6) Cb _ ,>; Dr VAN KERKHOVE,Maria (b)(6); KABIR, Sophia ""'::::====~~ NIH-001252 (b)(6)'> ; FARES,Christine Youssef (b)(6) -----Subject: The global health leaders call, Wednesday 4 March at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 4 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficult ies joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It wou ld be appreciated if you could kindly confirm your participat ion to Ms Sophia Kabir, email : CbH 6Jt; mobile no. (b)(6) ------- The agenda and background documents will be shared ahead of t he call. Best, M ike NIH-001253 From: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:44:07 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: [EXTERNAL) RE:Hardball Tonight Date: To: Subject: FYI. (b)( . ----- Original Message ----From: Matthews , Chris (NBCUniversal, MSNBC) Date: Wednesday , Febrnary 26 , 2020 2:39 PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: Re: [EXT ERNAL] RE: Hardba ll Tonight ------~~ When you can and are ready , Twould love to have you on Hardball anytime in the 7pm hour tonight , tomorrow or Friday. Sent from my iPhone > On Feb 26, 2020, at 11:34 AM, Fauci, Anthony (NlH/NlAID) [EJ ______ Cb_ H_, 6)> wrote: > > Chris: > I am always happy to be on your show . I am hearing that they want us to hold on doing any interviews for the time being since the POTUS might do a press conference tonight. > Tony And so the decision is still in flux. > > Anthony S. Fauci , MD > Director > National Institute of Allergy and Infectious Diseases Building 31, > Room 7A-03 > 3 LCenter Drive , MSC 2520 > National Institutes of Health > Bethesda , MD 20892-2520 > Phone (b) (6) > FAX: (301) 496-4409 -------- > E-mail: (b)(6) > The inf orma tion in this e-ma il and any of its attachments is confiden tial and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ie nt . Tfyou have received this e-mail in error plea~e inform the sender and delet e it from your mail box or any other storage devices. The National lm;titule of Allergy and Infectious Diseases (NIAID) shaJI not accept liability for any statements made that are the send er's own and not exp ressly made on behalf of the NIAID by one of its representatives. > > ----- Original Message ---- > From: Matthews , Chris (NBC Universa l, MSNBC) > Date: Wednesday, February 26, 2020 9:04 AM > To: Fauci, Anthony (NlH/NIAlD) [E) (b) ( > > Subject: Hardball Tonight ------~= > > Dear Tony- > > Coul d you come on tonight to address the coronavirus? We'd like to > have you on anytime in the 7 hour. (b) (6) > > Best, Chri s NIH-001254 > > Sent from my iPhone NIH-001255 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:35:33 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Can you chat? To: Subject: Please set this up. Thanks. From: Fox, Lauren Date: Wed nesday, February 26, 2020 5:41 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)c-c (= > Subject: Can you chat? Hey Dr. Fauci, I wanted to reach out because I am working on a big piece about the effort behind the scenes to contain the coronavirus and I was hoping you could talk on background about that, Best, Lauren Fox Lauren Fox Congre ssional Reporter CNN Politics Lauren.Fox@turner.com (b)(6) NIH-001256 From: Date: To: Subject: Coronavirus Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 04:34:46 +0000 Arturo Casadevall RE: My OpEd on the WSJ coming out Friday on convalescent serum fo r Arturo: Thank you for your note and for sending the Op Ed. Nice Job! I hope that all is well w ith you. Best, Tony From: Arturo Casadevall (b)(6)> Se nt: Wednesday, February 26, 2020 5:45 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: My OpEd on the WSJ com ing out Friday on convalescent serum for Coronavirus Dear Tony, I just had an OpEd accepted in the WSJ proposing the use of convalescent sera to stem the coronavirus epidemic. The text of the OpEd is below in blue font (scroll down). I am sure the WSJ will shorten it and edit it but at least you have an advance copy of it. I just wanted you to have it since the WSJ is read widely in DC and I don't want anyone blindsiding you with quest ions about it. As you know I have been long proponent of passive antibody therapies in infectious diseases and there is a huge body of historical data support ing this approach. Certainly, with modern blood banking techniques this option can be made quite safe and administration of a few cc' s of serum could confer immediate immun ity to those who will be exposed - like ER staff . I hope you agree with the message and like it. Thank you for all you are doing for the country and humanity . If you need me for anything in this crisis rest assured that I am here. Warm regards, Arturo From: Taranto, James Date: Wednesday, February 26, 2020 4:27 PM To: Arturo Casadevall (b)(6)> Subject: Re: Asking for a quick decision on the submitted OpEd on stemming coronavirus epidemic OK, we'll take this and aim to get it out in Fr iday's paper, though it will likely need some trimming for space. Dear Mr. Varadara jan, NIH-001257 I wonder if the WSJ is interes ted in my OpEd. I am trying to get a message out that conva lescen t serum (e .g . serum from people who recover) can be used to stem the coronavirus epidemic if admini stered to exposed people. This has been known for ove r a century, and is well accepted, but not wide ly known, even among experts today. There was one report that China was beg inning to stockpile serum but there has been almost no discuss ion of this option among world public health authorities . Although I can get this published in a medical journal my hope is to publish it instead in a venue of high readership since this is something that can be done today to stem the epidemic. I am hoping that given the econom ic consequences of the outbreak that the WSJ is interested . I included a brief bio below. Thanks for looking at this. Arturo Prop osed op-ed. To Stem the Coronavirus Epidemic use Survivors Blood. (b) (4) NIH-001258 (b)(4) Arturo Casadevall MD, PhD Author's brief bio Arturo Casadevall, M.D., Ph.D., is a Bloomberg Di stinguished Profes sor and Chair of the Molecular Microbiology and Immunology at Johns Hopkin s School of Public Health. He received his M.D . and Ph.D. degrees from New York University. He completed his internship/residency in internal medicine at Bellevue Hospital and specialized in Infectious Diseases at the Albert Einstein College of Medkine . The author of over 800 papers , books and chapters, bis major research interests are in fungal pathogenesi s and the mechanisms of antibody action. He is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Depu ty Editor of the Journal of Clinical Investigation and serves on several editoria l boards . He has served on severa l NIH committees including the NIA ID Strategic Plan , the Blue Ribbon Panel on Biodefense Research , the NAS panel tha t reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity . He was a Commissioner NIH-001259 in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas. He is currently the Chair the Board of Governors of the American Academy of Microbiology. He has received numerous honors including election to the American Society for Clinical Investigation , American Academy of Physicians , American Academy of Microbiology , Fellow of the American Academy for the Advancement of Science , American Academy of Alts and Sciences and the National Academy of Medicine . Arturo Casadevall MD, PhD Chair, Molecular Microbiology & Immunology Alfred & Jill Sommer Professor and Chair Bloomberg Distinguished Professor Johns Hopkins School of Public Health 615 N. Wolfe Street Room E5132 Baltimore, Maryland 21205 NIH-001260 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:48:12 +0000 Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff Date: To: (NIH/NIAID) [E] (b)(5) Thanks . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 5, 2020 10:15 PM To: Fauci, Anth ony (NIH/NIAID) [E]----(b)(6); --= (b-" H= 6J>; Lerner, Andrea (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E] (b)(6) (b) (5} Importance:High (b) (5l From: "DLGDESK (HHS/ASPR/OPP)" Date: Thursday, March 5, 2020 at 6 :19 PM --------~= To: "Stannard, Paula (HHS/I0S)" (b)(6) "Agnew, Ann (HHS/10S)" __. _ CbH >, "Trueman, Laura (HHS/IEA)" (b)(6)"Kadlec, Robert (OS/ASPR/I0)" CbH6) 1 >, "Bird, Catherine (OS/OGC)" CbH >, "Hittle, Taylor (HHS/ASFR)" CbH6J>, "Arbes , Sarah (HHS/ASL)" CbH6)>,"Murphy, Ryan (OS/ASPA)" CbH6)>, "Destro, Brenda (HHS/ASPE)" CbH >, "Nevel, Amy (HHS/ASPE)" CbH6J>, "Tobias, Constance (HHS/DAB)" CbH6J>, 11Giroir, Brett (HHS/OASH)" CbH >, "Schwartz, Erica (HHS/OASH)" CbH6J , "Severino, Roger (HHS/OCR)" CbH6J>, "Grigsby, Garrett (HHS/OS/OGA)" CbH6J>, "Kerr, Lawrence (HHS/OS/OGA)" CbH >, "Chang, Wi llia m (HHS/OGC)" CbH6J 1 >, 11Tait sman, Julie K (OIG/I0)" CbH6)>,"Gr iswold, Nancy (HHS/OMHA HQ)" (b)(6)>,"Rucke r, Donald (OS/ONC)" (b)(6J 1 >, "Johnson, ....;.,= Lynn (ACF)" CbH6>1>, "Meyers , David (AHRQ/ I00) " (b)(6) "McNellis, Robert (AHRQ/CEPI)" (b)(6)>, "Patel, Anita (CDC/DDID/NCIRD/0D)" (b)(6), 11 Et hier, Kathleen (CDC/DDID/NCHHSTP/DASH)" CbH6)>,"Brookes, Brady (CMS/DA)" (b)(6) "H inton, Denise (FDA/OC)" CbH6)>,"Cheever, Laura (HRSA)" (b)(6) ________ ---:-"""""".'"."."'::======~~~ -------- --------- --:-'."""'.'~-=====:...:... __ ==========:-;:~ ------------- ---------- NIH-00096 1 "Espinosa, Diana (HRSA)" Cb)( >, "Macrae, Jim (HRSA)" Cb)( >, "Weahkee, Michael (IHS/HQ)" CbH6)>,"McCollum, Jeffrey T (IHS/HQ)" CbH6)>, "Frazier, Francis (IHS/HQ)" Francis (NIH/OD) [El" CbH>, Anthony Fauci CbH6)>, Hilary Marston CbH6J 1>, "Mccance-Katz, Elinore (SAMHSA/OAS)" (b)(6) "Shuy, Bryan (OS/ASPR/10)" -----~~ CbH6)>, "Yeskey, Kevin (OS/ASPR/10)" CbH6), Rick Bright CbH6)>, "Disbrow, Gary (OS/ASPR/BARDA)" CbH6J>, "Phillips, Sally (OS/ASPR/SPPR)" CbH >, "Greene, Jonathan (OS/ASPR/EMMO)" CbH6), 11 DeBord, Kristin (OS/ASPR/SPPR)" CbH6)>, "Vineyard, Michael (OS/ASPR/10)" CbH6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" (b)(6), "Imbriale, Samuel (OS/ASPR/SIIM)" (b)(6), "Donne IIy, Kelsey (OS/ASPR/SPPR)(CTR)" CbH6)>, "Haris, Mariam (OS/ASPR/SPPR)(CTR)" CbH6)>, "Fucci, Michael (OS/ASPR/SPPR)(CTR)" (b)(6)>,"Roman-Stolte, Claudia (05/ASPR/SPPR) (CTR)" (b)(6) , "Austin, Meredith (uscg.mil)" CbH6J>, "Perdue, Christopher (OS/ASPR/SPPR)" CbH6)>, "Herrmann, Jack (OS/ASPR/OEA)"_ __:__ _:_======:: (b ~)(~6):,- ~R'o""'.' b_e_rt'""'.' Jo-:h-n-so- n (b)(6) ":':""'.'"-:---.---".""'.""':~~-:--:'"'.""."'.":====--__;_~ ~ ------- ---------------- ---------- Wong, Diana (OS/ASPR/SIIM)" CbH6J> , "Robertson, Lance (ACL)" CbH6)>, "Nicholls, Richard (ACL)" (b)(6) "Phillips, Christine (ACL)" CbH6)>, "Blatner, Gretta (OS/ASPR/BARDA)" CbH6)>, "Feeney, Kathryn (OS/ASPR/10}(CTR)" CbH6J>, 11ShirIe y, Mayo (FDA/OC)" CbH>, "Sheehy, Janice (FDA/ORA)" (b)(6)"McDaniel, Eileen (HHS/OMHA)" CbH6)>, --:----:-----::======~~~ Linda Lambert Cb)( >, "Gin, Julia (OS/ASPR/SPPR)" CbH6), "Adams, Steven A. (CDC/SNS/DSNS)" (b)(6),"Wolf, Laura (OS/ASPR/SIIM)" CbH6J>, "Lee, Scott (OS/ASPR/EMMO)" CbH6)>, "Cooper, Kevin (OS/ASPR/ORM)" CbH6)>, "Moudy, Robin (OS/ASPR/SPPR)" CbH6)>, "Lawrence, Theresa (OS/ASPR/SPPR)" CbH6J, "Baker, Michael (OS/IEA)" CbH6J> Cc: "Holland, Tara (OS/ASPR/EMMO)" CbH>, "Delvecchio, Paolo (SAMHSA/OMTO}" CbH6), "Lobos, Elisa (SAMHSA/OFR/0D)" >, "Bell, March (HHS/OCR)" CbH6), "Frohboese, -:-----:---:----:-::--::====:....:.__..:.,_ __ .:..,__..:,_~~ Robinsue (HHS/OCR)" (b)(6),"Knutson, Donna (CDC/DDNID/NCEH/OD)' (b)(6)"Mackay, Thomas (OS/ASPR/EEAA)" ;____;,_ __ ..:.,__...:____;,_.=-~~-----=~ .......~--~----"".'":"."':== Cb =H=6)'..... M_a_n.:::. g...: o'....: P_a_u....: I (....: H_H~S/:.... l~OS)" CbH6)>, "Blackford, Carol W. (CMS/CM)" CbH6J>, "Bradsher, Kris (HHS/ASL)" CbH6)>, "Payne, Skip (CMS/OA)" CbH6J, "Gettinger , Andrew (OS/ONC)" CbH6)>, "Abbey, Rachel (OS/OSCP)" CbH6)>, "Cosgrove, Sandra (OS/ASPR/EEAA)"-------~= CbH6)>, 11Cha put, Daniel (OS/ONC)" CbH6) (b)(5) 11 -------- -:========~......., = ----------- ------- ~====~~-~-----:-" · -------- NIH-000962 .-..----.-.-= Dear Disaster Leadership Group (DLG) Members , (b) (5) We are asking that you review this draft and provide feedback to us by 8 :00am on Friday, March 6. Please note that we are looking for subst antive feedback only . If you have any quest ions or concerns, please reach out to me a copy the DLGDESK@hhs.gov . ---------- Cb)(6) and kindly Thank you, Daniel Dodgen, Ph.D. Senior Advisor Office of the Assistant Secretary for Preparedness and Response (ASPR) Office of Strategy, Policy, Planning and Requirements {SPPR) HEALTHAND HUMAN SERVICES (DHHS) I O'Neill House Office Building DC 20515 o. (b)( --------- (b)(6) I www .phe .gov NIH-000963 I 200 C Street SW I Washington, From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 3 Mar 2020 11:12:55 +0000 (b)(6) (OS/IOS) RE: Single-cell RNA expression profiling of ACE2,the putative receptor of Wuhan To: Subject: 2019-nCov I bioRxiv Oh, I see what they are getting at. They examined at the single cell level the expression of RNA for ACH2, which is the receptor for the Coronavirus in the lung ,and found that when they looked at various demographic groups there was greater expression of this recep tor in Asian males. They are thus hinting that this is the reason why there was such an explos ion of infections in China. This is possible, but the lowest level was in Northern Ltalians and take a look at what is happening in Nort hern Ttaly. I do not mean to put the paper down since there may be some truth in it. However, this journal (bioRxiv) is not peer reviewed and the data are skimpy. Someone should do a more scholarly st udy. ----- Origina l Message ----From: (b) (6) (OS/1OS) (b) ( Date: Tuesday, March 3, 2020 5:54 AM-----~~ To: Fauci, Anthony (NIH/NlAID) [E] (b)(6) > Subject: Re : Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-oCov -------=,.,..,.= I bioRxiv They asked if this proved certain ethnic groups more likely to get the disease and 1 said I had never anything like that suggested to me by our leading scientists. > On Mar 2, 2020, at L0:44 PM , Fauci, Anthony (NIH/N[AJD) (E) > (b) ( wrote: I do not know what question they asked you about th is paper , but any question about this gene expression paper to a non-scientist wou ld be unfair and inappropriate. -----Original Message----From: Cb)(6) (OS/IOS) Cb)(6)> Date: Monday, March 2, 2020 9:55 PM To: Fauci, Anthony (NlH/NIAID [filJ Cb)(6)> ; Redfield , Robert R. (CDC /OD) Cb)(6) Cc: Harrison , Brian (HHS /IOS) (b) (6), Subject: Single-cell RNA expression profiling of ACE2 , the putative receptor of Wuhan 2019 -nCov I bioRx iv -------=~=-- Was asked about this on tv tonight. https: //www .biorxiv .org/co ntent/ 10.110 1/2020.01.26.9 19985vl NIH-001022 Fauci, Anthony (NIH/NIAIO) [El Tue, 3 Mar 2020 03:26:29 +0000 Collins, Francis (NIH/OD) [E);Giroir, Brett (HHS/OASH) Steele, Danielle (HHS/IOS);Tabak, Lawrence (NIH/OD) [E] RE: SARSCoV-2 in humanized mice From: Date: To: Cc: Subject: Ditto. From: Collins, Francis (NIH/OD) [E] (b)(6) Se nt: Monday, March 2, 2020 9:32 PM To: Giroir, Brett (HHS/OASH) Cc: Fauci, Anthony (NIH/NIAl ~ D:-'. ) [:::E':"" ] Steele, Danielle (HHS/10S) (b)( ; Tabak, Lawrence (NIH/OD) [E] (b)( Subject: RE: SARSCoV-2 in humanized mice ------~= ~:::::::::~ :::·>; --------- Larry has it right . Tony may want to add. Francis From: Tabak, Lawrence (NIH/OD) [El (b)(6) Date: Monday, March 2, 2020 8:14 PM -------=-=-=- To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) ~ [E:':" ) ====== ~ )~(~ (b 6)>; Fauci, Anthony (NIH/NIAID) [E] CbH >; Stee le, Danielle (HHS/10S) (b)(6) Subject: Re: SARSCoV-2 in humanized mice -------Brett, I hope this helps. Larry -------Date: Monday, March 2, 2020 at 7:25 PM From: "Giroi r, Brett (HHS/OASH)" < (b) (6) , To: "Tabak, Lawrence (N IH/OD) [E]" Cc: Francis Collins Danielle _ _:__;___;_::...:,~~"""'.'""--:---:--".-::::==------=..,..=, Anthony Fauci ---=======::::!..~~ (HHS/ 10S)" "Giroir, Brett (b)(6) 1>, CbH6)>, (b)(6) Subject: RE:SARSCoV-2 in human ized mice NIH-001025 (b)(6)>, (HHS/OASH)" "Stee le, Dear Larry, I appreciate your will ingness to cont inue to work on this and respond to the questions that I am receiving . V/r Brett Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Thu rsday, February 20, 2020 5:29 PM To: Giroir, Brett (HHS/OASH) Cc: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Ant hony (NIH/N IAID) [E] (b)(6); Steele, Danielle (HHS/10S) (b)(6)> Subject: Re: SARSCoV-2 in humani zed mice ~ :.:======;:~ -------Brett , I have discussed w ith both Francis and Ton ·----------------- (b) (5l W ith regard to your questions: (b) (5) NIH-001026 (b) (5) Hope this is helpf ul. Please let me know if you require additional info r mat ion . Best wishes, Larry From: "Giroir, Brett (HHS/OASH)" 0 ate : Thursday, February 20, 2020 at 12:32 PM To: "Tabak, Lawrence (NIH/OD) [E]" --------------- (b)(6) ..----.-.-= ;.....:. ___..!======~~Cc: "Stee le, Danielle (HHS/10S)" ---------Subje ct: RE: SARSCoV-2 in human ized mice (b)(6) (b)(6) (b)(5) Brett P. Giro ir, MO ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [El Date: Thursday, February 20, 2020 12:19 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) (b)(6) (b)( > (b)(6) ,> Subject: Re: SARSCoV-2 in humanized mice NIH-001027 (b) (5) Thanks Larry From: "Giro ir, Brett (HHS/OASH)" Date: Thursday, Februa ry 20, 2020 at 12:17 PM To: " Tabak, Lawrence (NIH/OD) [El" (b) (6) 1> ----------- ---------=--=-= ;.....:.-=======~~"Stee le, Danielle (HHS/10S)" ---------RE:SARSCoV-2 in human ized mice (b)(6) Cc: Subject: (b)(6) Larr (b)(5) Brett P. Giroir, MO ADM, USPublic Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Tabak, Lawrence (NIH/OD) [E] Date: Wednesday,February 19, 202011 :04 PM To: Giroir, Brett (HHS/OASH) Cc: Steele, Danielle (HHS/10S) Subject: FW: SARSCoV-2in humanized mice (b)(6) (b)(6) (b)(6) Brett, (b) (5) Thanks for your consideration, Larry From: "Hasenk rug, Kim (NIH/N IAID) [El" Date: Wednesday, February 19, 2020 at 5:50 PM ----------NIH-001028 (b)(6) ________ To: "Tabak,Lawrence(NIH/OD)[E)" ,__ Subject: SARSCoV- 2 in human ized mice (b)( 6) (b) (5) Hi Dr. Tabak (b) (5) Best regards , Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories National Institute of Allergy and Infectious Diseases National Institutes of Health 903 S. 4th Street Hamilton, MT 59840 (b)(6) Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives NIH-001029 Fauci, Anthony (NIH/NIAID) [E) Mon, 2 Mar 2020 00:48:25 +0000 Cassetti, Cristina (NIH/NIAID) [E];Giroir, Brett (HHS/OASH) Conrad, Patricia (NIH/NIAID) [El RE: COVIDand Chloroquine From: Date: To: Cc: Subject: Thanks, Cristina --------------~~ From: Cassetti, Cristina (NIH/NIA ID) [E) Se nt: Sunday, March 1, 2020 7:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) (b)(6)> -------- (b)(6) --------- Cc: Conrad, Patricia {NIH/NIA ID) [El Subject: RE: COVIDand Chloroqu ine Giroir, Brett (HHS/OASH) (b) (6) > Hi, NIAD doesn't have ongoing trials with chloroquine and I heard that such tr ials are being conducted in China. We are planning to evaluate chloroquine in animal models ASAP. If any the rapeutic with a good clinical safety profile ( like chloroquine) appears to be effective in vivo against COVID-19, we are planning to quickly add to them to the Remdesivi r therapeutic trial as another arm. Let me know if you have other questions . Kind regards, Cristina Cristina Cassetti, Ph.D. Deputy Director Division of Microbiology and Infectious Diseases Nationa l Institute of Allergy and Infectious Diseases, NIH 560 1 Fishers Lane, Room 7GS1 Rockville , MD 20852 Tel: (b)(6) (b)(6) -------- From: Fauci, Anthony {NIH/N IAID) [El Se nt: Saturday, February 29, 2020 8:20 PM (b)(6) NIH-001057 To: Giroir, Brett {HHS/OASH) (b) (6l> "":"::-"'.""":"::-::.::=====--=--c-:-= (b)(6)>; Conrad, Patricia (NIH/NIAID) Cc: Cassetti, Cristina {NIH/NIAID) [E] (b) (6)> --------- [E] Subject: RE: COVID and Chloroquine Importance: High Brett: Thanks for the note. you. Best, Tony I will run this by the people in our Program and get back to Cristina: Are we or anyone else doing anything with clinical trials and chloroquine for COVID-19? Please respond directly to ADM Giro ir . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------------=-,--== -------- From: Giroir, Brett {HHS/OASH) Date: Saturday, February 29, 2020 9:31 AM To: Fauci, Anthony {NIH/NIAID) [E) (b) (6)> (b)(6) Subject: COVID and Chloroqu ine You know the old data and the new data. New in vitro look promising. Do you have good visibility on the trials being conducted? Or is NIH runn ing any of these? Your time is precious, so 10 word response sufficient. NIH-00 1058 Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-001059 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 1 Mar 2020 22:35:38 +0000 To: Kadlec, Robert (OS/ASPR/10) RE: Your thoughts Subject: My thoughts - ----- (b) (5) Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------To: Fauci, Anthony (NIH/NIAID) [ E]------~~ -------Subject: Your thoughts From: Kadlec, Robert (OS/ASPR/IO) Date: Saturday, February 29, 2020 10:03 PM (b)( > CbH6)> Importance: High Tony I don't know if you saw t his but wanted to ask your thought. Cb)<5> Your t houghts always appreciated bob << File: CCDCEpi Report.pptx >> << File: The+Epidemiological+Characteristics+of+an+Outbreak+of+2019+ COVID-19)+-+China,+2020.pdf >> NIH-00 1073 Novel +Coronavi rus+Diseases+( From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:55:20 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/NIAID) [E] RE:HHSCOVID-19 Response· alignment of OPDIV/STAFDIVEfforts I would recommend Dr. Hilary Marston from my immediate office. hear ing with us From: Collins, Francis (NIH/O D) [ E] Date: Saturday, February 29, 202010:48 PM Larry should go to the (b)(6) ---------.., ~ Fauci, Anthony (NIH/NIAID) [ E] (b)(6) Cc: Tabak , Lawrence (NIH/OD) [E] (bH6)> Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts To: Hi Tony , Quick question - who would you suggest is the appropriate NIH representa tive for this ASPR-led trans-HHS effort to coordinate COVID-19 response? You and I will be testifying in front of the House Approps Subcommittee on Wednesday morning . Would it be best for Larry to represent NIH for the ASPR gathering (though he would normally attend the House hearing), or is there someone from NIAID that would be most appropriate? Thanks , Francis --------- From: Kadlec, Robert (OS/ ASPR/10) Date: Friday, February 28, 2020 10 :23 AM (b)(6) Tru eman, Laura (HHS/IEA) -------~= (b)(6)>; Rowell, Scott (OS/ASA) (b)( >; Bird, Catherine (OS/OGC) (b)(6b; Moughalian, Jen (HHS/ASFR) (b)(6) , ; Arbes, Sarah (HHS/ ASL) (bH6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (bH >; Giroir, Brett (HHS/OASH) (bH6)>; Severino, Roger ":":"':-:--:-:-'.:-=--::::-:-;====::::::.._;__ _ __,;_= (HHS/OCR) (bH >; Grigsby, Garrett (HHS/0S/OGA) ,,:___;_ _ _;_:====;: (b-;:; )(;;6);->"-". ;K ::-e-r-r,-:-L-awrence ( HHS/0S/OGA) --------(b..H=6); To: Charrow, Robert (HHS/OGC) (b)( ; Grimm, Christi A (OIG/10) ..... -----:=======-..:._~= (b)( __::_.!:::::======~~- (bH6J>; Griswold, Nancy (HHS/OMHA HQ) ---------- 0 p Divs (b)(6)>; Johnson, Lynn (ACF) (b)(6) Robe rt son, Lance _;__;_::::::~;;--=-----:::--:-:---:--:----:::-:-=. (ACL) (bH6)>; Khanna, Gopal (AHRQ/100) ___ _;___ (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6) Verma, Seema ":'":-:--:-:-~-:-::::=====~_:_-~~ (CMS/OA) (b)( Saxon, Bobby (CMS/CCIIO) ,,:____:_..:..:::==========::::...-----.-.c,.; (b)(6) Hinton , Denise (FDA/OC) ----------------- NIH-001117 (b)(6)>; Engels, Thomas (HRSA) ":'-----:---:---'.=======-..:.._ -=~ -------(IHS/HQ) < (b)(6)>; McColl um, Jeffrey T (IHS/HQ) CbH6) ; Weahkee, Michael ~....:...-.;.....:=====~~:;---(b)( 6)>; Frazier, Francis (IHS/HQ) (b)(6)>; Collins, __ :.,,.,.= Francis (NIH/OD) [El CbH6) Fauci, Anthony (NIH/NIAID) [E] CbH6)>;McCanceCbH6)>;Mars ton, Hilary (NIH/NIAID) [E] Katz, Elinore (SAMHSA/OAS) (b)(6); Krohmer, Jon (dot.gov) (b)(6) ~-".""""'.'"."'"'"'"-:"".:~~~=::::!...:,_ 1 -------- ; --------------- ________ Cc: Ford-Barnes, Arwenthia (OS/ASPR/IO) Cb)C6J1; Waters, Cicely _, (b)(6) (OS/ASPR/OEA) CbH6);Shuy, Bryan (OS/ASPR/IO) Subject: HHS COVI0-19 Response - alignment of OPDIV/STAFDIV Efforts Dear ASPRColleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead efforts across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. Please provide the following information to ASPR.HCSRTF@hhs .gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, t itle, and contact information • OPDIV/STAFFDIVname • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) NIH-001 118 • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001119 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 03:26:56 +0000 To: Collins, Francis (NIH/OD) [E] RE: HHS COVI0 -19 Response - alignment of OPDIV/STAFDIV Efforts Subject: Francis: You are correct about the Israeli vaccine. I cannot imagine that they would have a safe and effective vaccine deployable in 90 days. Tony From: Collins, Francis (NIH/OD) [E] Date: Friday, February 28, 2020 12 :56 PM --------- To: Fauci, Anthony (NIH/NIA ID) [ E].------(b)(6) (b)(6)> -,_.(b-_.,-; )(= >; Tab ak, Lawrence (NIH/OD) [E] Subject: FW: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts Hi Tony and Larry, See below for a new Health Care Resilience Task Force being convened by ASPR. The initial meeting overlaps with our House approps hearing. Tony, who shall we send to this one? FC P.S. to Tony- I'm gett ing a lot of buzz about the Israeli claim to have fast track vaccine: https:// israelb .org/2020/02/israel-to-have-coronavirus-vaccine-within-3-weeks/ It looks to me that they are conflating having something ready to put into voluntee rs for a phase 1 trial, and having full scale production ready to go for the global needs. That still seems like it's a year away. Am I right? From: Kadlec, Robert (OS/ASPR/10) Date: Friday, February 28, 2020 10 :23 AM To: Trueman, laura (HHS/IEA) _______ (b)(6) -,; Cb ..,... H=6)>; Rowell, Scott (OS/ASA) (b)( · Bird, Catherine (OS/OGC) (b)( >; Moughalian, Jen (HHS/ASFR) (b)(6)Arbes, Sarah (HHS/ASL) (b)(6) Murphy, Ryan (OS/ASPA) (b)(6)>; Destro, Brenda (HHS/ASPE) (b)(6);Giroir, Brett (HHS/OASH) <: (b)( >; Severino, Roger ":""":":--:"':"":'."':~=====::...-__,; ~ (HHS/OCR) CbH6)> ; Grigsby, Garrett (HHS/OS/OGA) NIH-001 124 CbH >; Kerr, Lawrence (HHS/OS/OGA) CbH6)>; --------Charrow, Robert (HHS/OGC) Grimm, Christi A (OIG/I0) (b)(6)>; Griswold, Nancy (HHS/OMHA HQ) --~--=========--.:__~= Johnson, Lynn (ACF) < ---~-"."'-::::====::!....:.. ___ .:.........:~ (b)( >; CbH6)>; Op Divs Robertson, Lance (ACL) (b)( >; (b)(6)>; Khanna, Gopal (AHRQ/10D) CbH6);Redfield, Robert R. (CDC/OD) ":"".'"'""'."":""':"':'.""':"-:-"=======~--..~ (CMS/OA} (1-:-: H-:S/7H::-: Q7) ======:::....:..-,; CbH6)>;Verma, Seema CbH >; Saxon, Bobby (CMS/CCIIO) ..,, (b..,... )(~6) Hinton , Denise ( FDA/OC) <_ _;___;_:::=========:::::...;_ 7 (b)(6)>; CbH6)>; Engels, Thoma s (HRSA) -co. CbH6?j>; Weahkee, Michael (b;., H=6)>; McColl um, Jeffrey T (IHS/HQ) ---------------------- (b)(6); Frazier, Francis (IHS/HQ) Francis (NIH/OD) [El (b)(6), ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID} [El -------Katz, Elinore (SAMHSA/OAS) (b)( (b)(6) Collins, > (b)(6); Mccance- (b)(6)>; Krohmer, Jon (dot.gov) Cc: Ford-Barnes, Arwenthia (OS/ASPR/10) (b)(6)>; Waters, Cicely --:-----:---:----:--:-::=~...:_ __ ...:_~ ~ (OS/ASPR/OEA) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6)> Subject: HHS COVID-19 Response - alignment of OPDIV/STAFDIV Efforts -------- Dear ASPR Colleagues, We are at a critical juncture in our nation's response to COVID-19. As we pivot from containment of the virus to mitigation of its impacts, it is imperative that HHS moves swiftly, transparent ly, and in a unified manner to protect lives and save Americans. The Secretary has charged my office to lead effo rt s across the Department to prepare and defend our health care system during the novel coronavirus outbreak through the Health Care System Resilience Task Force. To date, this task force has engaged with public and private sector stakeholders to broadly identify efforts that can be taken to help ensure preparedness in response to a domestic COVID-19 outbreak, and more importantly their gaps, challenges, and potential areas of need from the federal government. Now, we must build on that knowledge to expedite and execute a whole of HHS response to support protection of the health care system that spans public health, health care, and human services. Please join Dr. Kevin Yeskey, ASPR's Principal Deputy Assistant Secretary for Preparedness and Response, and Dr. Nancy Messonnier, CDC's Director of the National Center for Immunization and Respirato ry Diseases, on Wednesday, March 4 from 9:00 AM -10:15 AM , at the O'Neill House Office Building for a working session to align current activities and next steps to be executed as part of a coordinated HHS response to COVID-19. NIH-001125 Please provide the following information to ASPR.HCSRTF@hhs.gov no later than Monday, March 2 at 12:00 PM, and be prepared to share and discuss at Wednesday's session. • Your Designee(s) name, title, and contact information • OPDIV/STAFFDIV name • OPDIV/STAFFDIVcurrent and future top five priorities related to COVID-19 (priority leads, descriptions, timelines) • OPDIV/STAFFDIVkey activities and workgroups (current and under consideration) related to COVID-19 response (include activity/workgroup leads, key purpose, timelines) • OPDIV/STAFFDIVkey areas of concern or challenges identified to date • OPDIV/STAFFDIVcore competencies or other assets it can bring to COVID-19 response efforts We look forward to working with you on this critical effort to defend the nation's health care system. Thank you in advance for your support and participation. Respectfully, Bob Kadlec ASPR NIH-001126 From: Date: To: Cc: Subject: Att achments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 15:45:23 +0000 Zebley, Kyle (HHS/0S/OGA) Ker r, Lawrence (HHS/0S/OGA) RE: Current TF Agenda Draft/Request fo r AMA High -level Talkers Task Force VP Briefing 2-13-20 - with Fauci TP.docx Kyle: Here is a t alking point fo r t he messaging secti on. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Zebley , Kyle (HHS/05/0GA) (b)(6) sent: Thursday, February 27, 2020 9:11 AM (b)(6); To: Hall, Bill (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) Trueman, Laura (HHS/I EA) (b)( >; Johnston, Darcie (HHS/I EA) (b)(6)]; Arbes, Sarah (HHS/ASL) (b)( ; Morse , Sara (HHS/ ASL) (b)(6)>; Twomey, John K. (HHS/ASL) (b)(6)>; Pence, Laura ':': (H ""."'. H -:-: S:-:/A "."". S :"." L-:; ) :====::!-:....._~ (b.,... )(,;; > =======::~;;---::--" Cc: Mango, Paul (HHS/10S) (b)(6) ; Bird, Catherine (OS/OGC) (b)(6) Grigsby, Garrett (HHS/OS/OGA) ,__"."""""''""""":":-""':-::::==(b = )~(~ >; Kerr , Lawrence (HHS/0S/OGA) (b)(6); Redfield , Robert R. (CDC/OD) (b)( >; McGowan , Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Conrad, Patri cia (NIH/NIAID) [E) (b)( 6); Kadlec, Robert (OS/ ASPR/10) (b)( >; Shuy, Bryan (OS/ ASPR/10) (b)(6) Subject: Current TF Agenda Draft/Request for AMA High-leve l Talkers Import ance: High -------Good morning, NIH-001249 Attached, please find a current draft of an agenda for a TF Briefing fo r VPOTUSthis afternoon. Note that t his is a draft and is not final. However, in order to prepare the Secretary, can ASPA, IEA, and ASL please help with 2-3 high-level talkers each the Secretary could highlight under the External Activity/Messaging section of the agenda ? Could you please send to me and Dr. Larry Kerr by 11 AM t his morning? Apologies for t he quick turnaround . Dr. Redfield, Dr. Fauci, and Dr. Kadlec, please note your presence on the agenda and please be prepared to speak to the topics assigned. Let me know if you have any questions. Thanks for your help. Kyle Zebley Chief of Staff Office of Global Affairs (OGA) Office of the Secretary U.S. Department of Health and Human Services Direct: (b)(6)/Mobile: (b)(6) Confidential and pre-d ecisiona l communi cation NIH-001250 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 20:08:22 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: mitigation in communi t ies COVID-19 Targeted Layered Mit igation Strategy_lnterim.022820.pdf I assume that you are OK with the document that Garrett just sent around. See attached. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/DDID/NCIRD/00) Date: Sunday, March 1, 2020 2:59 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: mitigation in communities ------~= (b)( (b)( From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Sunday, March 1, 2020 2:59 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) > ---~~ Cb _ >_<.... ~ Schuchat, Anne MD (CDC/OD) (b)(6)> Subject: mitigat ion in communities Here are the basic high level principles of a miti ation strate y. NIH-00 1087 (b) (5) (b) (Sl (b) (5l NIH-001088 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 28 Feb 2020 03:02:24 +0000 Grigsby, Garrett (HHS/OS/OGA) Subject: RE: ----------------- It is a tough decision, (b) (5) (b)(5) ·, ------------ ________ .... From: Grigsby, Garrett (HHS/OS/OGA) Se nt: Thursday, February 27, 2020 5:27 PM (b)( To: Fauci, Anthony (NIH/NIAID) [E]-------=- > c-c=>; Kadlec, Robert (OS/ASPR/I0) (b)(6) ; Adams, Jerome (HHS/OASH) --------Cc: Harrison, Brian {HHS/I0S) (b)( (b)(6) •> Zebley, Kyle (HHS/0S/OGA) (b)( > (b) (5) Subject: FW: ----------------1mpor tance: High Gentlemen, Any problem with this - see Marty's below. Need to know asap as I'd like to forward to NSCimmediately. Many thanks! From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Date: Thursday, February 27, 2020 5:08 PM To: Grigsby, Garrett (HHS/05/0GA ) ------- (b)(6) ------ ........, = (b)(6 )> Cc: Walker, Allison Taylor. (CDC/DDID/NCEZID/DGMQ) (b)(6) McGowan , Robert (Kyle) (CDC/0D/OCS (b)( Roohi, Shahrokh (CDC/0D1D/NCEZID/DGMQ) (b)(6) Elvander, Erika (05/0GA) (b)(6)>; Zebley, Kyle (HHS/05/0GA) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6) ~~~= 00~ Hi Garrett, (b) (5) (b)(5) CDC intends Thanks, Marty (b) (5) NIH-001231 (b)(5) NIH-001232 From: Date: To: Subject: Fa11ci,Anthony (NIH/N IAID) [E) Thu, 27 Feb 2020 04:31:21 +0000 MsP RE;A note from Sharon Perlman Sharon: Thanks for your note. It was great to hear from you. All is wel l with me and my family. hope the same for you This whole coronavirus situation is rather exhausting since I am work ing 24/7 with no breaks at all. However , it needs to be done since this virus is a true t hreat to global heath. Best regards, Tony From: Ms P (b)(6) Date: Wed nesday, February 26 , 2020 6:07 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: A note from Sharon Perlman ------- (b)(6)> Hi Dr. Fauci, As I was watching my favorite CNN news show starring Chris Cuomo last night , to my delight, there you were! And again, this morn ing with John Berman and Alisyn Camerota on New Day. I do hope all that all is well with you and your family. We are all do ing fine. My (b)(6) NIH-001266 I would love to hear from you, when you have time. With best regards, Sharon NIH-001267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 04:27:18 +0000 Bennett Werner Conrad, Patricia (NIH/NIAID) [El RE: Clinical question, Sir.... Dear Drs. Werner and Ubl: --------------------------Thank you for your note. = (b~, = ,""' , \V~ (b)(6) ----- Original Message--_-_ --_______ _ From: Bennett Werner (b) ( > Date: Wednesday, February 26, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAJD) [E] .__ _____ -------=-::-=, _ )_C... · (b Su~ject: Clinical question, Sir. ... Dear Dr. Fauci (b)(6) By the way, we both feel you are an outstanding spokesperson and really appreciate both the work you do and your clear explanations on Public TV (and elsewhe re). Warm regards, Bennett E. Werner , M.D. F ACC FACP Cleveland Clinic Cardiology (b) ( Michelle D. Uhl, M.D. Cleveland Clinic - medical oncology (b) (6) NIH-001268 To: Cc: Fauci,Anthony (NIH/NIAID) [E) Thu, 27 Feb2020 04:06:03 +0000 Morgan Fairchild Conrad, Patricia (NIH/NIAID)[El Subject: RE: Covid-19 From: Date: Morgan: Thanks for the note and the offer to help. It would be great if you could tweet to your many Twitter followers that although the current risk of coronavirus to the American public is low, t he fact that there is community spread of virus in a number of countries besides China and including South Korea, Japan, Italy, Iran among others poses a risk that we may progress to a global pandemic of COVID-19. If that occurs we will surely have many more cases in the USA. And so for that reason, the American public should not be frightened, but should be prepared to mitigate an outbreak in this country by measures that include social distancing, teleworking, t emporary closure of schools, etc. There is nothing to be done right now since there are so few cases in this country and these cases are being prope rly isolated, and so go about your daily business. However, be aware that behavioral adjustments may need to be made if a pandemic occurs. Best regards, Tony From: Morgan Fairchild (b)( Date: Wednesday,February26, 2020 8:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid - 19 -----~~ (b)(6)> Hi Dr. Fauci. I'm reaching out to see if I can help in any way to get good information out to the public , as I tried to do with AIDS. I have almost 10D,000 Twitter followers and have been tweeting articles to them that I feel are helpfu l, but if you have any info I can help disseminate, please let me know. Also , a great job today and this week!! Hope you're well! Thanks! Best, Morgan NIH-001269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 27 Feb 2020 03:00:14 +0000 Laura Landerman-Ga rber RE: Dr Sheldon Wolff Dr Fauci NIH Follow up 2/26/20 --------------- (b)(6) Laura: Many thanks for your kind note . It was great to hear from you. Warm regards, Tony From: Laura Landerman-Garber Date: Wednesday, February 26, 2020 9:26 PM To: Fauci, Anthony (NIH/NIAID) [E] --------------~ Subject: Re: Dr Sheldon Wolff Dr Fauci NIH 2/26/20 (b)(6)> ~ (b)(6)> --------------- CbH6JFollow up Greetings from New Hampshire. Today I was watch ing the news and there you were , once again popping up in my life and making me not only smile by your kind and approachable style that I truly remembe r from the Cb)(6), but also taken care of by your expertise. Thank you for your medica l leadership during these days as the Coronavirus spread s. Please know that your legacy of research and practice will live on for generations to come! I hope that these complex days are soon quieted for us here in the US and around the Globe (b)( Ps Amazing to th ink that so many of my que stions were answered all those decades ago with you and Sheldon Wolff I remain forever gratefu l. Since I saw you last, CbH6)who you met, moved to DC and works at American Psychologica l Association. Cb)(6) . Life marches 011. I hope you and your family are well --------------------------------- Best, Laura Landerman-Garber, Ph .D. On Apr 7, 20 15, at 12: 18 PM , Fauci, Anthony (NIH/NIAID) [E] CbH6Jwrote: Laura: Thank you so much for your beautiful note . I do remember you and am so happy that you reached out to communicate with me. I am very pleased to hear that you are doing so well. You have "made my day" by your note . I wish you and your family all the best. NIH-001270 Warm regards, Tony ~~~------- From: Laura Landerman-Garber Date: Tuesday,April 07, 2015 10:31 AM To: Fauci,Anthony (NIH/NIAID)[E] Subject: Dr SheldonWolff Dr FauciNIH up (b)(6) -------------- (b) (6) See below please. Thank you!! Sent from my iPhon e Begin forwardedmessage: From: Laura Landerman (b)( Date: April 7, 2015 at 10:06 :28 AM EDT To: "niaidnews @nia id.nih.gov " Subject: Dr Anthony Fa uci/ NIH/ Dr SHeldon Wolff l (b)(6) ' followup Reply-To: Laura Landerman (b) (6) Greetings from NH. I am trying to contact Dr Fauci after many ~ears . I have followed his career like so man others do... (b)(6) I am not sure if this can find its way to Dr Fauci but I would so appreciate it if it could. To let him know that all those years ago , NIH-001271 Follow he left n outstanding impression on CbH6) ___ I want to thank him from the bottom of my heart . Sincerely , Laura M. Landerman-Garber , Ph.D. (b)(6) (b)(6) NIH-001272 Fauci, Anthony (NIH/NIAID) [E) Thu, 27 Feb 2020 02:57:57 +0000 LOUIS FORTUNATO RE: Dear Tony: Will you take the lead in the Coronavirus prob lem/ we always love you/Saw you on CNN/ From: Date: To: Subject: Lou: I do not believe that there Best regards, Tony is a chance to republish Harrison Practice . ------------------ From: LOUIS FORTUNATO Date: Wednesday, February 26, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ~= (b)(6) Subject: Fwd: Dear Tony: Will you take the lead in the Coronavirus problem/ we always love you/Saw you on CNN/ Begin forwarded message: (b)(6)> From: LOUIS FORTUNATO Subject: Fwd: Any Chance of Harri son Practice being updated and replaced on the market ? I loved it Tony/ Better than Harri son's Textbook Date: February 17, 2020 at 9:41:40 PM EST To: Cb)(6) Dear Tony Fauci MD: Any chance for Harrison Practice being republished again and updated with the newest Pathophysiology and Treatments? It was better than Harrisons Textbook/More Precise and Succinct Please email me/ I would greatly appreciate your response either wayYes or No// Dr Lou Fortunato (b) (6); Begin forwarded message: NIH-001273 ----------- From: LOUIS FORTUNATO (b)(6)> Subject: HERETONY IS ANOTHER CHAPTEROF MY FUTURE NUC MED BOOK Date: November 3, 2019 at 5:11:19 AM EST To: (b)(6) HERE TONY IS MY NOTES IN BONE IMAG ING FO R MY FUTURE BOOK LOU FORTUNATO NIH-001274 From: (b)(6) Date: Wed, 26 Feb 2020 20:24:59 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: [EXTERNAL]Gene-RADAR platform for Real time Mobile (POC)Coronavirus detection/ viral load monitoring/ Followup to our meeting at the ASPENideas festival - Please bandle. Sent from my iPhone Begin forwarded message: From: "Dr. Anita Goel , M.D., Ph.D. " (bH6)> Date: Februa ry 26, 2020 at 7:58:54 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: FW: [EXTERNAL! Gene-RADAR platform for Real time Mobile (POC) Coronavirus detection/ viral load monitoring / Followup to our meeting at the ASPEN ideas festival - ---------=-:-:-= Dear Dr. Anthony Fauci, It was a great pleasure meeting you all a couple of years ago when we were both speaking at the Aspen Ideas Festival. Some of my contacts at the CDC recently briefed me about the rapidly emerging threat of the coronavirus to the US and have been urging us to develop an app for detecting coronavirus with high sensitivity and specificity on our Gene-RADAR platform . Our platform has the ability to quantify vi ral loads in ' real-time' which would be a much more precise and accurate solution in deciding quarantine than the current thermometers or even the current CDC coronavirus test which has a very poor Limit of detection (ie low sensitivity). We have a strong track record of responding to previous pandemic threats and rapidly building Gene RADARapplications for Ebola and Zika and then getting them through clinical validation as per the the FDA EUA approval process. Our Gene-RADARZika test was FDA EUA certified right as the Zika crisis was coming to an end . I would love to work with you to see how we can help in your efforts to rapidly respond this deadly threat to the US and the world. Here are some of the capabilities of our platform that we believe could be an enabler for helping to stop this out break from becoming a full-fledged global pandemic. NIH-001278 to • Gene-RADAR platfo rm for Real time M obile (POC)Coronavirus detection/ viral load monitoring o Highly sensitive and specif ic - minimize false positives and false negatives o With very good LOD'swe could potent ially start to catch people presymptomatically and enable the early detection, early quaran ti ne would limit the spread and early intervention could lead to better outcomes o More precise viral load mon itoring could help determine when to release people from quarantine or ICU beds o Our platform's ability to quantify vial loads could change clinical trial endpoints fo r new drug candidat es or (repurposed drug formulation s), thereby accelerating FDA approvals for novel therapeutic regimen o We already have an ISO 13485 certified manufactur ing facility (currently in Boston) that we are prepared to move as fast as possible to ramp up our production We would love to work with you to repurpose our FDA approved platform for the above coronav irus applications assay and help your noble efforts to stop th is o utb reak from becoming a full blown global pandem ic that could costs t housands of lives and cause trillions of dollars of economic damage to the global economy. We would love to speak with you to br ief on o ur capabilit ies and discuss how we can qualify for some of the emergency funding being made available to help tackle this pandemic threa t . Happy t o j ump on a phone call to discuss furthe r how we can help How Nanobiophysics can Stop Ebolaand Other Global Pandemics • Forbes • Wired Magazine Best Wishes, Dr. Anita Goel, MD, PhD Chairman &CEO Nanobiosym ----------------------------------------------------------------www .nanobiosym .com email : (b)(6) Mobile : (b)(6) http ://www. people.fas.ha rvard .edu/~goel/ email: goel@physics.harvard.edu --------------------------------------------------------------Selected Media links: Nanobiosym Gene-RADAR® X Prize Grand Prize Winner Video NIH-00127 9 Dr. Gael's Article in Scientific American Worldview Nanobiosym Chairman &CEO Named 2018 Uber ELITEAward Winner FDA Grants Emergency Use Authorization for Gene -RADAR® Zika Test BBC Feature : The Genius Behind the "Tricorder that could revolutionize medicine" Nanobiosym Selected As One Of The Top Growth Stage Ventures By The 'Unreasonable ' Group Dr. Anita Goel, MD, PhD awarded 2019 SEEMA Entrepreneur of the Year Awa rd How Nanobiophysics can Stop Ebola and Other Global Pandemics • Forbes • Wired Magazine Nanobiosym Global Initiative Summit Website Wall Street Journal Washington Post Boston Globe GameChangers National Geographic Forbes Nanobiosym Space News CBS News Boston Business Journal CNN DailyMail Space.com Popular Mechanics Forbes US News and World Report W ired Daily Press CBC Radio Boston Globe STAT CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee. or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in a11yunauthorized manner. To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidentlal. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001280 CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate , nor distribute it to anyone else or use it in any unauthorized manner . To do so is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY: This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. CONFIDENTIALITY · This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use it in any unauthorized manner. To do so is strictly prohibited and may be unlawful . If you receive this email by mistake, please advise the sender immedia tely by using the reply facility in your mail software and delete it from your computer CONFIDENTIALITY : This email and attachments are intended for the above name only and are confidential. If you are not the intended addressee , or the person responsible for delivering it to the intended addressee, you may neither copy, disseminate, nor distribute it to anyone else or use It in any unauthorized manner . To do so Is strictly prohibited and may be unlawful. If you receive this email by mistake, please advise the sender immediately by using the reply facility in your mail software and delete it from your computer. NIH-001281 From: (b)(6) Date: To: Subject: Wed, 26 Feb 2020 19:24:48 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all ] Sent from my iPhone Beg in forwarded me ssag e: From: "Ander son, Liz" Date: February 26, 2020 at 6:57 :05 PM EST ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Cc: "Spitaln iak, Law·a" Subject: Interview request from WTOP [Please reply all] Good Even ing Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at W TOP . Are you available for a brief live interview (about 2 minu tes long) about wh at the latest COVID- 19 dev eloprne nts? During this evening' s press conference, Pre sident Trump said you two spok e about it. The Washington Post is also reporting that the CDC ha s been informed about the first corona virus case of unknown origin confirmed in North ern California. We'd also like to talk about that and what that coul d mean about the spre ad of this virus in the state s. We have the following time slots open tonight: 9:l0p 9:40p NIH-001282 10:lOp 10:40p 11 :I Op ll:40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895-5060 (newsroo m) landerson@wtop .com Twitter: @planetnoun http://wtop .com/autho r/ landerson/ http ://wtop .com/autho r/ liz-ande rson/ . 1 103.5 FM WTOP.COM NIH-001283 From: Date: (b)(6) Wed, 26 Feb 2020 19:24:09 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Interview request from WTOP [Please reply all) To: Subject: Sent from my iPhone Begin forwarded mes sage: From: "Anderson, L iz" Date: February 26, 2020 at 7:01:22 PM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Subject: RE: Interview request from WTOP !Please reply all] Wait- - I see you're at the press conference, too. If you have availability at one of the ti mes listed , we'd love to have you. Many thanks, Liz From: Anderson, Liz Date: Wednesday, February 26, 2020 6:57 PM To: (b)(6)> Cc: Spitalniak, Laura Subject: Interview request from WTOP [Please reply all] Good Evening Dr. Fauci, My name is Liz Anderson, and I'm working the editor's desk tonight at WTOP. Are you available for a brief live interview (about 2 minutes long) about what the latest COVID-19 developments? During this evening's press conference, President Trmnp said you two spoke about it. NIH-001284 The Washington Post is also reporting that the CDC has been informed about the first coronavirus case of unknown origin confirmed in Northern California. We'd also like to talk about that and what that could mean about the spread of this virus in the states. We have the following time slots open tonight: 9:l0p 9:40p 10:l0p 10:40p 11:l0p 11 :40p Many thanks for your time. Sincerely, Liz Anderson AE/Editor/Reporter, WTOP News 202-895- 5060 (newsroom) lande rson@w top .com Tw itte r: @planetnoun http ://wtop .com/au t hor/ landerson/ http://wtop .com/au t ho r/ liz-anderson/ 1 103.5 FM WTOP.COM NIH-001285 From: (b)(6) Date: To: Subject: and NIH Wed, 26 Feb 2020 19:22:28 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: AM 970 the Answer Radio Request Re: Coronavirus Response from POTUS Sent from my iPhone Begin forwa rded message: From: A lex Gan ett < agar rett @nycradio.com > Date: Februa ry 26, 2020 at 7:13:41 PM EST To: "Fauci , Anthony (NIH/NlAI D ) [E]" ---------=-:-:-= CbH6) Subject: AM 970 the Answer Radio Request Re: CoronavirusResponse from POTUS and NIH Hi Dr. Fauci, I hope you are well! Would love to welcome you to Kevin McCullough Radio on AM 970 the Answer tom orrow to discuss the steps the White House and the NIH are taking to combat coronavirus. Kevin is our drive-time host at 5 PM and he is nationally syndicated as well with 300+ affiliates fo r his broadcast! Look forward to hearing from you . Thanks Dr. Fauci! Alex Garrett Producer: Kevin McCullough Radio AM 570 the Mission WMCA: 3-4 PM AM 970 the Answer: 5-6 PM NIH-001286 From: Date: To: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 21:50:05 +0000 Laurencot, Elizabeth;Fauci, Anthony (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Cc: (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lane, Cliff Subject: RE: NEJM content proof (Fauci) Eli , (b)(5) Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 4:45 PM To: Fauci, An thony (NIH/NIAID) [El------~ (b~)(~6) Cc: Conrad, Patricia (NIH/NIA ID) [El (bH ; Lane, Cliff (NIH/N IAID) [E) [El (b)( > Subject: RE: NEJM co ntent proof (Fauci) ~-======~~ (b)(6)>; Eisinger, Robert (NIH/NIAID) [El (b)(6) Folkers, Greg (NIH/N IAID) -------- Dear Dr Fauci, Regarding the following information -(b)(5) Please clarify--- thank you! Best, Eli NIH-001287 From: Folkers, Greg {NIH/ NIAID) [E) [El -------- (b)~ > On Behalf Of Fauci, Ant hony (NIH/ NIAID) Date: Wed nesday, February 26, 2020 3:48 PM To: Laurencot, Elizabeth ; Fauci, Anthony (NIH/N IAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ~-~--~=== (b)( ":" [E :-:l.::=======. -------- ; Lane, Cliff (NIH/NIAI D) [El (b::: )(::: 6):!:.. ; _E_ is_ in.:::. ge~r~, ~ Robert (NIH/NI AID) [El (b)(6)>; Folkers, Greg (NIH/N IAID) (b ~~~(6) Subject: RE: NEJM content proof (Fauci) Dear Eli, (b)(5) NIH-001288 Thanks, Tony From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] CbH >; Conrad, Patricia (NIH/NIAID) [E] ~======'~~ (b)(6)>; ":": (N "'.".' l'."'." H/7N"."." IA '."'." l':"'. D):-:[~E]:-===~-~ Eisinger, Robert (NIH/NIAID) [El (b~H=6) (b)(6)>; Lane, Cliff Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will rev iew today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/N IAID) [E] Date: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) (b)(6)· Conrad, Patricia (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony "'.'--.---~~===:!._;__...:::..~= {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE: NEJM content proof {Fauci) (b)(6)>; Dear Eli, Here are my answers to you r queries, and co upl e other minor changes: (b)(5) NIH-001289 (b) (5) NIH-001290 (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives. NIH-001291 From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ = Subj ect : NEJM content proof (Fauci) Imp ort ance: High Dear Dr Fauci, Attached is the content proof of your editorial. Please rea d *A LL* of th e fo llowi ng instr uctions and inform ati on carefull y befo re you begin reviewing your proofs . First, please st op and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder . Your editoria l has been edited for grammar, consiste ncy, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication , we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publicatio n of your ed itorial. Please read the entire proof carefully, including all queries. Please return your query rep lies and proof corrections ** before 12pm (US Eastern) thi s Friday, February 28, 2020 **. Instruct ions are provided below . Note that you will be reading for content only; the article will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at th is stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. TO ANSWER THE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforwa rd, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-ma il message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article. Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! NIH-001292 Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READ THE PROOF : You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe .com/products/acrobat/readerma in.htm l ). This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distrib ution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended NIH-001293 recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001294 From: Date: To: Subject: (b)(6) Wed, 26 Feb 2020 15:29:21 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: Seeking Or. Fauci for coronavi rus webina r Let us discuss On Feb 26, 2020, at 11:59 AM, Conrad, Patricia (NIH/NIAID) [E] (b) C6Jwrote: ----------- Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he informat ion in this e-mail and any of its attachments is confiden tial and may contain sensitive information. It shou ld not be used by anyone who is nol the orig inal intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Chris Adams Date: Wednesday, February 26, 2020 11:01 AM To: Conrad, Patricia (NIH/NIAID) [E] ________ Subject: Seeking Dr. Fauci for coronavirus webinar --------~~ (b_H_6) Patricia: I hope you are doing well. Dr. Fauci has been a wonderfu l speaker for us in the past, and I'm reaching out to him today for a discussion on coronavirus. When the re are major news stories, we often will try to do a live webinar on the top ic with a leading expert or two. NIH-001295 This is something we would do in our stud io at our office near Dupont Circle. We normally do them for 45-60 minutes, and we take questions (visa Twitter) from our audience. The audience would be reporters who cover the topic, as well as others interested in the topic . It is a way to have an in-depth, thoughtful conversation about a pressing topic. Here are a couple we've done (the first is on Zika a few years ago): Zika panel discussion: https://nationalpress .org/topic/understanding -the -zikathreat/?st =O&t=&mm=Video Ted Koppel: https ://nat ionalpress.org/ t oolbox-topic/ lights-out -risks-t o-t he-power grid/?st =7042&mm =Video Autonomous vehicles panel discussion: https://nat ionalpress.org/top ic/wha t s-new-w it hautonomous -veh icles/?st =8474& t= Automat ion&mm =Story We'd like to do one of these on coronavirus . We'd love to have Dr. Fauci as our prime guest . We can schedule it around his demands, but would of course love to do it as soon as possible. We know he is in demand at this moment. But he is such a singular expert on the topic we'd love to have a discussion with him - one that would help get his message out to journalists (and others) who need to be informed to best cover the topic. Is it possible to check with Dr. Fauci to see if this is possible? Thanks, Chris Adams National Press Foundation NIH-001296 From: Date: (b)(6) To: Cc: Subject: Wed, 26 Feb 2020 15:01:39 -0500 Folkers, Greg (NIH/NIAID) [E) Eisinger, Robert (NIH/NIAID) [El Re: ASF and CLIFF------- DRAFT response to Eli at NEJM Please send this to Eli. Thanks On Feb 26, 2020 , at 12:49 PM, Folkers, Greg (NIH/N IAID) [E] (b) (6) wrote: ---------Dear Eli, (b)(5) NIH-001297 From: Laurencot, Elizabeth Se nt : Wednesday, February 26, 2020 11:54 AM To: Fauci, Antho ny (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6) >; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Eisinger, Robert (NIH/NIA ID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E) (b)(6) Subject: RE: NEJM content proof (Fauci) Importan ce : High Dear Dr Fauci, (b)(5) Thank you very much for your consideration! Best, Eli From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony (NIH/N IAID) [El ----- -----= (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El CbH >; Eisinger, Robert (NIH/NIA ID) [El (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, NIH-001298 Many thanks for your quick reply and for the clear list of responses regarding the proof . I will review today and will let you know if the re are any items needing further discussion. The current plan is for publication early Friday afternoon. As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli From: Fauci, Anthony (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 2020 7:37 AM To: laurencot, Elizabeth Cc: Folkers, Greg (NIH/NIAID) [El (b)(6); Conrad, Patricia (NIH/NIAIO) [El Cb)( >; Eisinger, Robert (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: RE;NEJM content proof (Fauci) Dear Eli, Here are my answe rs to your queries, and couple other minor changes: (b) (5) NIH-001299 (b) (5) NIH-001300 (b) (5) Than ks, Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Ant hony (NIH/NIAID ) [El Subject: NEJM conte nt proof (Fauci) Importance : High ------~~ Dear Dr Fauci, NIH-00130 1 (b)(6) Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt , so that we can be assured that your proofs did not end up in a spam folder. Your editoria l has been edited for grammar, consistency, readability, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict with Journal style or create grammatical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your editorial. Please read the entire proof carefully, inclu ding all queries. Please return your query replies and proof corrections **before 12pm (US Eastern) th is Friday, February 28, 2020**. Instructions are provided below . Note that you will be reading for content only; the article w ill be rendered for print after the content has been finalized . The Journal's senior medical editors w ill be reading your article at th is stage. If they have any additional comments or queries for you, I w ill forward them to you in the next few days. TO ANSWER THE QUERIES:The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions; please do **NOT** use e-annotation tools) and convey any additional changes as needed . TO RESPOND BY E-MAIL : If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there . You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do * *NOT* * use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-4347847 or at Med iasupport@ne jm.org . Again, please do confirm receipt at this time. Thank you very much for your efforts with these content proofs! Best, Eli NIH-001302 Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487-6547 elaurencot@nejm.org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file. Acrobat Reader is available free of charge at the Adobe Web site (http ://www .adobe .com/products/acrobat/readermain .html ). This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-001303 From: Date: To: Cc: (NIH/NIAID) [E];Folkers, Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Wed, 26 Feb 2020 17:33:08 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia Greg (NIH/NIAID) [E];Marston , Hilary (NIH/NIAID) [E] RE: remarks for White House press conference Fauci remarks Feb 26 - with minor edit .docx I have made a minor tweak . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Date: Wed nesday, February 26, 2020 12 :26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Billet , Courtney (NIH/N IAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [E) (b)(6J>; Conrad, Patricia (NIH/NIAID ) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6); Ma rston, Hilary (NIH/NIAID) [El (b)( > Subject: remarks for White House press conference ·'======~~ Dr. Fauci, Attached for review are proposed remarks (in bullet format) for t he White House press conference. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C NIH-001309 Bethesda , MD 20892 Direct: Cb)( Disclaimer: The information in this e-mail and any of its attachmentsis confidentialand may contain sensitive information. It should not be used by anyonewho is not the original intendedrecipient. If you have received this e-mail in error please informthe sender and delete it from your mailboxor any other storage devices. The National Institute of Allergy and Infectious Diseases shall not acceptliability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001310 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16 :49:43 +0000 Conrad, Patricia (NIH/NIAID) [El FW: BBC Radio What say you? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Paul Coletti Date: Wednesday, February 26, 2020 11 :47 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: BBCRadio --------- (b)(6) Dear Dr. Fauci, Newshour on the BBCWorld Service is today cover ing the US preparedness on the Coronavirus Would you be available for int erview on this topic? We're on air at 3pm eastern and could speak to you live at around 3:10pm or alternat ively we could record a few minutes between now and then . About 8 minutes duration and we've many ways to connect to get good audio (no video as we are radio) . If there is interest from your side then I'm on+ ------ Yours sincerely, Paul Coletti Tel: (b)(6) Tv. itter: @bbcworldservice, @pcoletti Newshour podcasts: www.bbc.eo.uk/ podcasts/series/newshour NIH-001311 (b)(6) BBC World Service listen live: www.bbc.eo.uk/worldserviceradio/on-air Newshour is the award-winning news and current affairs programme 011 BBC World Sen·ice English. the radio and 011/ine network which reaches 75 million listene,:f each week, including 11.5 million in the USA 011 National Public Radio. Paul Coletti Tel: Cb)(6) Twillcr: fa)bbcworldscrvice, @pcolettl Newshour podcasts: www.bbc.eo.uk/podcasts/sc1ies/newshour BBC World Service listen live: www.bbc.eo.uk/worldscrviceradio/on-air Newshour is the l/\Vard-11'i1111i11g news allll cw·rent affairs programme 011BBC World Sen•ice English, the radio a11d 011li11e network which reaches 75 million listene,~~each week, including 12.5 million in the USA 011 National Public Radio. NIH-0013 12 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:37:50 +0000 Johnson, Martin S. (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [E];Harper, Jill (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE:Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19Supplemental Request Martin : You and Hugh shoul d be on t he call. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martins. (NIH/NIAID) [El (b)(6) Date: Wednesday, February 26, 202011 :17 AM To: Fauci, Anthony (NIH/NIAID) [E] Cb~>; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6J>; Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIA IO) [E] (b)(6) Subject: Appropriators going to have a call at 3:30 in Larry's office with HHSOp divs on the COVID-19 Supplementa l Request ----------Tony, Appropriators going to have a call at 3:30 in Larry's office with HHSOp Divs concerning the 2020suplemental request. Larry wants someone from NIAID to also be on the call. Please advise who you want to attend . Thanks NIH-0013 13 Martin NIH-001314 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:36:36 +0000 Conrad, Patricia (NIH/NIAID) [El FW: SIBFinquiry Please say no to this. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Shannon Williams Date: Wednesday, February 26, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: SIBFinqui ry (b)(6J> Importance: High Dear Dr. Fauci, I am writing to inquire about your willingness to address the Society of Internat io nal Business Fellows (SIBF)as part of our webinar series. SIBFis a distinguished organization of nearly 1600 global executives and senior leaders. Our C-level global membership would appreciate getting your perspectives on the coronavirus outbreak. We are open to topics which could include ....What we know and don't know ...As business and community leaders what SIBFmembers can do to prepare and educate t heir employees ...Safety of travel, etc. We were thinking the webinar could be approximately 30 minutes in length (15 minutes of rema rks followed by 15 minutes of Q&A). SIBF'sCommun icat ions Manager could work with someone on your team to set-up the webinar. SIBFis a NIH-001315 non-profit, but we are able to provide a $2k honorarium to you or a charity of your choice . Thank you for your graciou s consideration and att ention to our request . It is our sincere hope that you w ill be able to participate. Best regard s, Mr. Shannon George Williams I Director of Programs Society of International BusinessFellows (SIBF) 715 Peachtree Street NE, Suite 200 Atlanta, GA 30308 P: (470) 378-1151 W : www.sibf.org NIH-001316 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 16:27:37 +0000 Conrad, Patricia (NIH/NIAID) [El FW: MSNBC Guest Request 2/26 FYI. Please hand le as you see fit. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hirsch, Nancy (NBCUniversal) Date: Wednesday, February 26, 2020 10:59 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: MSNBC Guest Request 2/26 --------::.:-=.. Hello Dr. Fauci I hope this finds you well and I am sure receiving numerous requests Would you be avail to join anchor Ari Melber tonight 6 pm EST to speak to Trumps presser and the latest on Coronavirus ? Thank you for letting me know if you can join soonest possible. Nancy Nancy Hir sch NIH-0013 17 The Beat with Ari Melber Mavericks with Ari Melber Booking Producer 30 Rockefeller Plaza I New York, NY 10112 (T) 212-664-4097 (C) (b)(6) .q,,MSNBC NIH-0013 18 From: Date: To: Subject: See below. Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:22:0 1 +0000 Eisinger, Robert (NIH/NIAID) [El;Greg Folkers FW: NEJM content proof {Fauci) ---------- (b)(6) I w ill need your help on thi s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Laurencot, Elizabeth Date: Wednesday, February 26, 2020 9:04 AM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Folkers, Greg {NIH/N IAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [El (b)(6)>; l ane, Cliff "."' (N - I-H-/ :N-IA - l~ D~ ) [~E]~===.;..~ (b~H=6) --------, ...,....,= Subject: RE: NEJM content proof (Fauci) Dear Dr Fauci, Many thanks for your quick reply and for the clear list of responses regarding the proof. I will review today and will let you know if there are any items needing fur ther discussion. The current plan is for publication early Friday afternoon . As I mentioned yesterday, there is a new article on Covid-19 that is also scheduled for publication that day, and the Journal editors would like you to mention it in your editorial. I expect to be able to send you a proof of that article sometime today. Best, Eli (b)(6) ________ From: Fauci, Anthony (NIH/N IAID) [E] Se nt: Wednesday, February 26, 2020 7:37 AM To: Laurencot, Elizabeth NIH-0013 19 _, Cc: Folkers, Greg (NIH/NIAID) [E] Cb)( >; Conrad , Patricia (NIH/NIAID) [E] ---:----:-~~= (b =)=(6) :!.. >..:.. ; _E_ is_ in.::::. ge~r;_ ,= Robert (NIH/NIAID) [E] ~ (b)(6) .>; Fauci, Anthony (NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: RE: NEJM content proof (Fauci) Dear Eli, Here are my answe rs t o you r que ri es, and couple ot her min or changes: (b)(5) NIH-001320 (b) (5) NIH-001321 Tha nks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:5 1 AM To: Fauci, Anthony (NIH/ NIAID) [E) (b)(6) Subject: NEJM content proof (Fauci) Importance: High ------~~ = Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully befor e you begin reviewing your proofs. First, please stop and take a moment now to confirm receipt, so t hat w e can be assured that your proofs did not end up in a spam folder. Your ed itorial has been edited for grammar, consistency, readability, adherence to Journal style, and clarity fo r nonspecialist readers. To expedite publication , we do not ask authors for specific approva l of routine changes; please read the enti re article to make sure your meaning has been retained. Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems. Finally, please note that a delayed or incomplete response may delay publication of your ed itorial. Please read the entire proof carefu lly, including all queries . Please return your query rep lies and proof corrections **before 12pm (US Eastern) this Friday,February28, 2020** . Instruct ions are prov ided below . Note that you will be reading for content only; the art icle will be rendered for print after the content has been finalized . The Journal's senior medical editors will be reading your article at t his stage. If they have any additional comments or queries for you, I will forward them to you in the next few days. NIH-001322 TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end. The query markers and the queries are linked, so you can jump back and forth within the file. Please respond to all the queries (see below for instructions; please do ** NOT** use eannotation tools) and convey any additional changes as needed. TO RESPONDBY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy) . Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, wh ich may lead to errors in your art icle. Please note that this material is confidential and embargoed until publication . If you have questions about our embargo policy, please contact NEJM Media Relations at 781 -434-7847 or at Mediasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts w ith these content proofs! Best, Eli Elizabeth Lauren<;:ot Senior Manuscript Editor New England Journal of Medici ne 617 -487 -6547 elaurencot@nejm .org TO READTHE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this fi le. Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readermain.html ). NIH-001323 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001324 From: Fauci, Anthony (NIH/NIAIO) [El Date: Wed, 26 Feb 2020 15:18:06 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: First in class, hemostatic drug - potential therapeutics for COVID-19 Attachment s: NIAID EEEV- SP16_ Jan 28, 2020 - Read-Only - Read-Only.pdf, JACCmanuscript Oct 2017 SP16 AM I (1).pdf , Serpin Pharma - Non-Confident ial Partnering Deck v29.pdf Please t ake a look at this. Thanks . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------, (b)( From: Cohava Gelber Date: Tuesday, February 25, 2020 8:45 PM To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Subject: First in class, hemostatic drug - potential therapeutics for COVID-19 Import ance: High ---------- .....,....,= Dear Dr. Fauci, (b) (4) NIH-001327 (b) (4) Please let us know how we can he lp. I have attache d a manuscript and company presentations for your review. Sincere ly, Cohava Cohava Gelber , PhD , MBA Execu tive Chairperson & CEO Serpin Pharma www .serpinpharma .com (b)(6) NIH-001328 Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 202015 :17:35 +0000 From: Date: Mehta, Nehal N. (NIH/NHLBI) [E) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers RE: Guidance for users of biologics in the age of Coronavirus. To: --------- Cc: Subject: I am sorry (b)( ·) Nehal, but I am really swamped right now and cannot make this a priority . I hope that you understand . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mehta , Nehal N. (NIH/NHLBI) [E] (b)(6)> Date: Tuesday, February 25, 2020 8:47 PM To: Fauci, Anthony (NIH/NIAID) [E)------~= (b)( > Subject: Fwd: Guidance for users of biologics in the age of Coronavirus. DearTony 1 wonder if you would be willing to participate in a short piece regarding use of biologics with looming Coronavirus for JAMA Dermato logy or JAMA Internal Medicine? Please see the email sent below to me by my colleague and collaborator Joel Gelfand from Penn. I understand there are fierce demands on your time but we would be happy to draft for your approval. Many thanks for your consideration! All my best, Nehal NIH-001329 Nehal N. Mehta, MD MSCEFAHA Lasker Senior Investigator Chief, Lab of Inflamm at ion and Cardiometaboli c Diseases National Heart, Lung and Blood Institute Bethesda MD 20892 Email Phone : (b)(6) """':====~~-(b)(6J1 Begin forwa rded message : Fro m: "Gelfand, Joel" -------------------------- (b)(6) Date: February 25, 2020 at 8:12:48 PM EST To: "Mehta, Nehal N. (NIH/ NHLBI) [E]" (b)(6) Subject: Guidance for user s of biologics in the age of Coro navirus. Dear Nehal, With the coronavirus border ing on a pandemic and the expectat ion that it will affect the US at some point, it seems to me we should be prepared to provide guidance to patients who are on im mune modulators for inflammatory disease. Specifically, many will wonder if patients should stop th eir biologic if the vi rus becomes prevalent in their commun ity. There w ill also be quest ions about stopping biologics in the setting of acute infectio n with coronavirus. Any thoughts on this? My specific inte rests relates to patients with psoriasis or psoriatic arthr itis on biologics but it's also relevant to patients w ith IBD, RA and other inflammatory diseases. Joel Joel M. Gelfand MD, MSCE Professor of Dermatology Professor of Epidemio logy Vice Chair for Clinical Research(Dermatology) University of Pennsylvania, Perelman School of Medicine https ://www .med.upenn.edu/gelfand/ NIH-001330 From: Date: To: Cc: (NIH/NIAID) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:14:43 +0000 Stover, Kathy (NIH/N IAID) [El Billet , Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW: Draft MA re: Fauci/Eisi nger/Redfield COVID-19 paper This look s fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the origi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover , Kathy (NIH/NIAID) [El (b)(6) Date: Tuesday, February 25, 2020 5:12 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Billet , Courtney (NIH/N IAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_C6);Conrad, Patric ia (NIH/NIAID) [E) (b)(6) --------, .....,..,= Subject: FORASF REVIEW: Draft MA re : Fauci/Eisinger/Redfield COVID-19 paper Hi Dr. Fauci, Please find attached for your review a draf t med ia availab ility about you r imm inent NEJM paper on COVID-19. We have name d you as the spokespe rson in t he MA. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Governmen t Relations National Institute of Allergy and Infec tio us Diseases National Institutes of Health 31 Center Drive, Room 7A17F NIH-001331 Bethesda, MD 20892 (b)(6) Media line: (301) 402 -1663 NIH-001332 From: Date: (b)(6) To: Subject: Wed, 26 Feb 2020 09:23:22 -0500 Thomas R. Frieden Re: FYI Thanks, Tom. On Feb 25, 2020, at 3:41 PM, Thomas R. Fr ieden ------------ Cb)(6)> wrote: Tony, Nothing you don't already know.... Tom (b) (6)> From: Tom Frieden Date: Tuesday, February 25, 2020 at 3:39 PM To: Tom Frieden (b)(6) Subject: A COVID-19 Pandemic is Inevitable. Now what? ------------- Dear Colleague, It's now clear that COVID-19 will become a pandemic. We don't know if it will be mi ld, moderate o r severe, or how many countr ies it will reach. As we shift from the initiation phase of the pandem ic to the acceleration stage, I've highlighted 8 things we must do now in a new CNN OpEd: htt p:// www .cnn.com / 2020/ 02/ 25/ health / coronavirus- pandemicfrieden / index. html Please share, and thank you for what you continue to do for pub lic health . All the best, Tom If you'd like to retweet, here's a link. NIH-001336 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 12:47:09 +0000 Collins, Francis (NIH/OD) [El RE: Milken outreach Thanks, Francis. It might be better for you to make an e-mail introduct ion and I will take it from there . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------- From: Collins, Francis (NIH/OD) [E] Date: Wednesday, February 26, 2020 7:32 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= = _ )_~... Cb ~> Subject: RE: Milken outreach He's at make an e- mail introduction? (b)(6) and ------ (b)(6) Want to reach out directly or shall I Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 6:43 AM To: Collins, Francis (NIH/OD) [El Subject: Re: Milken outreach (b)(6) (b)(6) Francis: Thanks for the note. Milken can help in a number of ways including directly supporting the VRC. Also, as we start looking for Pharma to step up with us, his connections could be helpful. Tony On Feb 25, 2020, at 12:58 PM, Collins, Francis (NIH/OD) [E] NIH-001337 ------- Cb)~ > wrote: Hi Tony, I'm sure you know Michael Milken. I've worked with him over many years, and though he is a somewhat controversial figure he has certainly helped NIH in many ways. He reached out to me last night to ask if there is anything he could do to help with the coronavirus vaccine effort. He had seen press reports that finding a pharma partner had been challenging - and wanted to volunteer his help in that regard, since he has deep connections in the private sector. He also said that he'd be glad to help with any philanthropic needs, both through his own resources and his influence over members of the Giving Pledge. Are there useful actions that I can suggest to him? FC NIH-001338 From: Date: Wed, 26 Feb 2020 10:59:30 +0000 To: *'@ ~ Subject: RE: Questions abou t the coronavirus-Chinese Fauci, Anthony (NIH/NIAIO) [E) Media Inquiry : See answers below in red From: $.~~~ Date: Wednesday, February 26, 2020 1:08 AM To: Fauci, Anthony (NIH/NIAID) [E) -----.. (b=H= > Subject: Questions about the coronavirus-Chinese Media Inquiry: Dear Dr Fauci, My Name is Paul Xin, I'm a journalist from Pengpai News(ThePaper) of Shanghai, which is one of the most important new medai in China. I 'm Sorry to bother you as you must be very busy. I noticed your comment about coronavirus on American media, I deeply hope you could answer few of my questions.Your answers will be very helpful to me. The questions are below. Thank you very much! Sincerly , Paul Xin 1/You said on CNN that US have had pandemic preparedness plan that developed in preparation for pandemic influenza . Could you provide some detai ls of this plan? The plan outlinesthe differences between containmentand mitigation. It speaks of the thing that shouldbe done if an outbreak occurs in the USA. Thes incluesocial distancing,useof telecommunicationand telework, temporarily closing schools, avoidingcrowed placessuch as indoor arenas and theaters. 2/To prepare for potent ial communities spread of coronavirus in US, do you thin k that US need take the measures similar with China? China was in the "reactive " mode of responding to an explo sion of cases in Wuhan Cityand Hubei provincewith spreadthroughoutChina. Chinahad to resort to very dramatic measuressuchas shutting down cities. The USAis now in a preparativemode and not a reactivemode and so our responseis muchdifferent than that of China. NIH-001339 $}!.;Ji ~;JUJr[i:i]/8"1~~Jr[i:i] cp,t,f~ ~~Wfrfijjfm ..t.;fifmN~cpns39~ NIH-001340 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 10:46:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Confirma tion from CNN's New Day Got it. Thanks . From: Conrad, Patricia (NIH/NIAID) [E) Date: Wednesday, February 26, 2020 5:40 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] -------=- (bc-H= > Subject: Fwd : Confirmation from CNN's New Day Firm for 650 am hit today at med arts as per below. Sent from my iPhone Begin forwarded message: From: "Figliola, Mike" Date: February 26, 2020 at 3:33:40 AM EST -------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)>, "Daniels, Ronnel (NI H/0D /0 RS)[CJ",,....;._;...__.;..;....:.......;::;: (b;:; )(56)'>,-::":-:R-:yl-an-d:-, K :-:e-n-:-(-:-N IH/0D/ORS) [El" (b)(6)>, Jonathan Bennett --------Farrar, Joy (NIH/OD/ORS) [E)'-------===~~.-------________ (b_H_6) (b)((;), "Jackson Subject: RE: Confirmation from CNN's New Day Hi everyone, This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Wednesday 02.26.20 at around 6:50am ESTto discuss: Coronavirus latest - are we facing an outbreak? You will be solo at 6:45am ESTfor the segments. John Berman, will both be conducting today's interview. Please arrive at the studio no later than 6:40am EST. Here is your studio confirmation: NIH-00134 1 SHOW MANAGER : VENDOR STUDIO #2018562 NIH Events Management (Medical Arts) Studio Info NIH Control Room numbers are 301-827-8478 and 8479 Encompass Booking and Circuit Number: Booking: 1-800-243-1995 Circuit: 36TBGS 104492 Our IFB: 30 1-496-1811 (we prefer to call into the station's IFB) Video : 1080i (59.94 ) - the audio is embedded . Please call the TOC with any technical questions at 301-827-8478 Please confirm you have received this and are all set to go! Best, M Mike Figliola Editorial Producer CNN's New Day 212-275-8161 mike.figliola@ turner .com CONF IDENTIALITY NOT ICE: This e-mail transmission, and any documents , files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient , or a person responsible for delivering it to the intended recipient , you are hereby notified that any disclosure , copy ing, distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Tha nk you. NIH-001342 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 01:32:22 +0000 Jon LaPook RE:CBSSunday Morning Jon: The message would have to be that the situat ion continues to evolve and people need to follow the news and the reports from CDC. For example , a few weeks ago if you wanted to travel to Japan or South Korea , it was fine since there were few is any cases there. Now both cotmtries have a travel alert that says "Avoid all but essential travel". You should tell people that travel to places with few or no reported cases is fine. Only when you have community spread (person to person to person) shou ld you be concerned about a specific travel destination. Also , you cou ld explain to people that pandemics evo lve when a new infectious disease is spreading by sustained community spread in multiple countries in different regions of the globe. Once a [)andemic erupts. it is virtually impossible for any country to be free of cases. Peop le need to understand that. You can mitigate the effects , but you cannot avoid having infections since you cannot shut off the country from the rest of the world. Also, you need to speak of the rea l and present danger of seasonal influenza every year. Do not let the fear of the unknown (i.e. a pandemic of a new infectious agent) distor t your evaluation of the 1isk of the pandemic to you relative to the risks that you face every day. The only thing that we can do is to prepare as best as possible and do not yield to wrreasonable fear. Best, Tony •··•-Original Message----From: Jon LaPook ,,;::;... ---~ (b ~)~(= > Date: Tues day, February 25, 2020 6:34 PM To: Fauci, Anthony (N1H/NlAID) [E] Subject: CBS Sunday Morning ------ ~~> (b)( Hi Tony, 1 have an unusual opportunity: the executive producer of CBS Sunday Morning has asked me to do a straight to camera shpiel about COVID-L9for this Sunday. 1did something similar when people are panicking about Ebola. You and 1have spoken enough about th is so that I feel comfortable with the basics. But I would love you to give some thought to whether there are any misunderstandin gs that you would like cleared up or information you would like disseminated. l would love to give some logical travel advice. I know there are so many unknown s, but r have had multiple people ask me whether they should cancel their upcoming to trip to ... you name it (ltal y, Israel, San Francisco). T know it comes down to risk/benefit , and - as you told me during the Ebola outbreak - people hav e all sor ts of vary ing leve ls of comfort with risk. But what do fac tually SAY to the 6 million people who will be watc hing people? :) Thanks, Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLa Pook NIH-001344 From: Date: (b)(6) Tue, 25 Fe b 2020 19:07:15 -0500 To: Subject: McNeil Jr, Donald G Re: thought from a kibb itzer ... You make some very good points , Donald. On Feb 25, 2020, at 4:48 PM, McNeil Jr, Donald G w rote : I was j ust watching the HHS briefing online, and thinking about an article I read this morning , and Bruce Aylward's description of what he saw in China, and a lot of videos I've w atched on the South China Morning Post website (they're doing great coverage .) . In China, we in the med ia tend to report the horr ors a nd the lockdown and the governme nt's early lies ... But the truth is that a lot of average Chinese behaved incredibly heroically in the face of the virus: 25,000 doctors and nurses wen t into Wuhan to help, knowing they might die. Average people gave up their stockpiles of masks so they could be shipped to Wuhan . Ne ighb orhood committees brought food to thousands of little old ladies and checked on them eve ry day, even as they asked them to stay behind their doors for fear of infection. Meanwhile , in America, people tend to act like selfish pigs interested only in saving themselves. How can I hoard a mask? Where's my vaccine? This morning , I read this appa lling article from A la bama . Here you have Americans com ing back from a horrifying experience overseas, and the President -- who is popula r in Alabama -- asks Alabama ns to take some of those fellow Amer icans in. There is zero risk because they're going to be housed on a naval base. And yet, the answer is "No! Keep them out!" And their legislators encourage it.... I dunno -- that's the kind of behavior I expect from my fellow New Yorker s, not from Alabama. If the virus arrives -- and we both know it wilJ -- America is going to have to do better than that. Like the Chinese, Americans are going to have to look out for each other the way we haven't since 9/ 11. Or maybe since World War II . But that's not the tone of the HHS briefings . Th ey're an aggressive, defensiv e, almost smart-alecky "we got this" tone. The only time the tone was right when you NIH-001345 were the third to take the mike and explain things to that kid shouting from the back without a mike about "What's the real message? What do we do?" Maybe there could be some thought given to mentally preparing Americans to work together in the face of the crisis? Quarantines are a very aggressive approach -- but they require a lot of compassion or the people quarantined suffer. I might get around to writing an article about this, but my editors keep grabbing me for minute by minute stuff and I'm way behind. Donald NIH-001346 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 18:59:02 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Surfactant Protein-D against coronavirus Please handle. Begin forwarded message: From: Marc Salzberg Date: February 25 , 2020 at 4:42:47 PM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Cb)(6J CbH6J Subject: Surfactant Protein-D against coronavirus Dear Dr. Fauci, We are developing a recombinant human form of Surfactant Protein-D (AT-100), an endogenous collectin w ith strong irnrnune-modu latory properties. AT-100 shows anti-inflammatory and ant i-infectious properties. CbH4> There are data indicatin that SP-D clears coronavirus (b)(4) While we are discussing this with a number of academic institutions, I was wondering, though, whether you and the NIH are interested to collaborate on eva luating AT-100 against coronavirus. Please let me know , if you are willing to schedule a phone ca ll with our Chief Medical Officer Dr. Paul Kingma and I to discuss. There is obviously a sense of urgency behind this request. Best regards, Marc Salzberg Airway Therapeutics , Inc. Marc Salzberg, MD President &CEO 1200 Johnson Ferry Rd., Suite 300 Marietta, GA 30068 Ph (b)( NIH-001347 : : AIRWAY ( • • THH"l..A I T ~ NIH-001348 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 18:33:00 -0500 David - Gmail Re: David Pyrce Reconnecting - Coronavirus Task Force David: Thanks for your note and your keen interest in this important challenge of coronavirus. The White House Task Force is chosen by the President upon the advice of his senior staff. I am afraid that there will not be any additionalmembers for now. Again, thank you for your interest. Best regards , Tony On Feb 25, 2020, at 5:29 PM, David - ----------- (b)( wrote: Hello Dr. Fauci, I know you are extremely busy and will get right to the point. I would like to jo in the coronavirus taskforce. I worked on the Ebola task force about six years ago, which had a similar sense of urgency, and recognize that assembling a SWAT team overnight is critically important in order to monitor, contain and mitigate the spread of the coronavirus, not just for the United States, but on a worldwide basis. I've done a significant amount of work in infectious disease vaccine development at a number of biotech firms (Vical, lnovio and lntrexon) in partnership with the NIH, Vaccine Research Center, DOD and the CDC. I also (b) (6) we discuss preparedness on a daily basis. Those conversations clearly indicate that the knowledge and expertise is severely lacking at both the academic medical center level, as we ll as the community health level. I believe my assistance can be deployed in several areas where my experience in virology , immunology, antivirals , Ebola, product development and strategic partnering could be of immediate value to research scientists, medical professionals and healthcare systems. 1. Identification of emerging therapeut ics. 2. Fast track emerging therapeutics from pre-clinical to IND and fast-track clinical trials. 3. Identify opportunities to accelerate the product ion of commercial quantities of therapeutic material. 4. Identify unique genomic fingerprints of responders and patients undergoing treatment to guide therapeutic selection and optimize interven tions. 5. Interface with public and/or institutional stakeholders on a worldwide basis (24/7) regarding safety procedures, diagnostics, therapeutic interventions, etc. 6. Other initiatives, representing areas where there is an immediate need to bring on board and deploy an individual with deep expertise, who can provide leadership , drop in and rapidly advance those initiatives . NIH-001349 With the urgently required , in order to provide a Navy SEAL like response , I would propose a consulting arrangement where I'm avai lable 24/7 , anywhere/a nytime , for as long as needed . Please let me know your thoughts . Here is a brief snapshot of my C.V. 1. SVP , Innovation and Chief Commercia l Officer - NantKwest (gene/cell therap ies , immunotherapeutics and molecular diagnost ics) 2. SVP, Innovation and Chief Commercia l Officer - NantHealth {A l/bioinformatics-based multi-omics based molecular diagnostics and neoant igen-based therapeutics) 3. Founder/CEO - Genomic Principles (neoantigen-based , individualized therapeut ic vaccines) 4. Founder/CEO Canton Biotechnologies {DNA-based therapeutics and vaccines) 5. Chief Business Officer - lntrexon {gene/protein-based therapeutics and vaccines) 6. Chief Business Officer - lnovio {gene-based therapeutics and vacc ines) 7. VP, Business Development - Vical (gene-based therapeutics and vaccines) . I know you are busy and you can feel free to forward th is emai l to the appropriate individual. I can also be reached by ce ll phone (b)(6) to discuss furthe r. Best Wishes, David (b)(6) NIH-001350 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 22:10:15 +0000 NIAIDODAM FW: Hello from ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Groslyn Burton Date: Tuesday, February 25, 2020 10:59 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Hello from ------ -==-(b)(6J> ---------- Dr. Fauci (b)(6) I apologize for the direct out of the blue message, however, my company The Asia Group has a pod cast called Tea Leaves and we would be interested in having you as a guest to speak about the Coronavirus. I mentioned to my CEO that you are the leading expert and that I had a connection with you. We would only take about 30-45 mins of your time and would be happy to work around your schedule if this is something that you would be willing to do. Below is a short description of the podcast and a link to our episodes. If able, I'd be happy to coordinate with your assistant. Looking forward to hearing back soon. Thanks, Groslyn "Foster" Burton Vice President, Culture and Values Executive Assistant to the Chairman Dr. Kurt M . Campbell, Chairman and CEO The Asia Group, LLC NIH-001351 202-350-3285 - Office Cb)(6) - M obile 202-750-29 44 - Fax ----- he Asia Group announc ed the launch of Tea Leaves, a new podcas t that will focus on the current affa irs, foreign policy, business, and arts of As ia. The podcasts' hosts, Dr. Kurt M. Campbell and Ambassador Richard Verma, will lead a series of revealing interviews with policymakers , business leaders, journalists, and artists exploring the most dynamic and consequentia l region in the world. In a j oint statement, Campbell and Verma said, "We wanted to share our passion for Asia with listeners , both accomplished Asia hands and those with a budding interest in the dynamic region. Our aim is to provide listeners with a greater understanding of the individuals who focus on and live in the region, and how Asia affects our world. " The ho sts bring sign ificant experience and expe rtise to the podcast. Campbell is CEO and Chairman of The Asia Group, and served as Assistant Secretary of State for East Asian & Pacific Affa irs from 2009 to 2013. Richard Verma is Vice Ch airman and Partner at The Asia Group, and served as the United States Ambas sador to India from 2015 to 2017. The first episode of Tea Leaves is now live on major podcast platforms , including iTunes , Stitcher, and Overcast. Subsequent episodes will be animated by conversat ions with the movers, doers, and thinkers who are driv ing today's Indo-Pacific. "We hope that you will subscr ibe and give our first episode a listen," sa id Campbell and Verma. Th e link to the podcast is available here: https://itunes.apple.com/us/podcast/the-tea leaves -podcast /id 135 5207045 NIH-001352 - From: (b)(6) Tue, 25 Feb 2020 16:08:53 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: The last Word with Lawrence O'Donnell Date: To: Subject: Let us discuss Begin forwarded message: From: "Shuster, Amy (NBCUniversal , MSNBC)" < amy.shuster @msnbc.com > Date: Februa ry 25, 2020 at 3:40:25 PM EST To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( , "Fauci, Anthony (NIH/NIAID ) [E]" (b)C --------~~ Subject: The Last Word with Lawrence O'Donnell Good afternoon, I wonder if Dr. Fauci could join our program this evening at 10 pm to discuss the best measures for the government and the American peop le to prepare for a coronavirus pandemic. Ali Velshi is hosting our show tonight on MSNBC. This would be a panel discussion this evening -w e're still working through details of the panel. Interview would be from 10-10:20 pm EST. Please let me know if anything would be possible tonight. Many thanks, Amy Amy Shuster Senior Producer The last Word 0. C. 212 -664-1657 (b)(6) NIH-001353 From: Date: (b)(6) To: Subject: Tue, 25 Feb 2020 14:03:48 -0500 Ziady, Hanna (NE) Re: Questions on coronavirus vaccine 45 people. It will take 3 to 4 months to complete. On Feb 25, 2020, at 11:12 AM , Ziady , Hanna (NE) wro te: Thanks very much for the quick response. Do you know at this stage when the phase 1 trial will be completed and how many people will participate in it? Many thanks, Hanna Hanna Ziady Writer I CNN Business 0: +44 207 693 1884 M: + (b)(6) @hannaziady From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 25 February 2020 at 15:58 ---------- (b)(6) To: "Ziady, Hanna (NE)" Subject: RE: Questions on coronav irus vaccine The phase 1 trial to determine safety for the mRNA vaccine platform that NIH is doing with Moderna is scheduled to start within 2 months (some time in April) . However, this is just the first step in attempting to have a vaccine available for use. Even proceeding at an emergency speed, a vaccine would not be available for use for at least 1 to 1.5 years. It is characterized as a "vaccine". Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-001354 Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ziady, Hanna (NE) Date: Tuesday, February 25, 2020 5:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Questions on coronav irus vaccine Dear Dr Fauci, Trust this mail finds you well . I have a few questions regarding the Moderna vaccine, which it wou ld be great to get your input on. Is it true that trials of the possible vaccine will start in April, but that, even if the first study is positive, the vaccine might not become wide ly available until next year because of the need for further studies and regulatory clearances? The company is characterizing this as a vaccine. Strictly speaking, what should it be referred to as? If you have time for a quick telephone call this morning as soon as you're able that would be great. Many thanks, Hanna Hanna Ziady Wri ter, CNN Business Office : +44 207 693 1884 (b)(6) Mobile : @hannaziady ------ Information in this email includ ing any attachments may be privileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. 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NIH-001356 From: Date: To: Subject: (b)(6) Tue, 25 Feb 2020 13:56:38 -0500 Conrad, Patricia (NIH/NIAID) [E) Re: cdc coronavirus This does not change anything I said this AM. It is perfectly compatible with what I said. No conflict at all. On Feb 25, 2020, at 1:32 PM, Conrad, Patricia (NIH/NIAID) [E] ----------- (b) (6)>wrote: Pis advise Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is nol the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jakaitis, Mike Date: Tuesday, February 25, 2020 1:26 PM To: Conrad, Patricia (NIH/NIAID) [E) Subject: cdc coronavirus ---------- (b)(6) The CDCtoday alerted Americans to begin to prepare for community spread of the coronavirus .....does t his changes Dr. Fauci's view on the virus? If so can he join us. If this doesn't change anything. We can use what he said this morning ....or if he wants to come on and ta lk about the new CDC warning ...we would like to speak to him. NIH-001357 From: (b)(6) Date: Tue, 25 Feb 2020 13:52:31 -0500 James Rae Re: touch screens transmitting Coronavirus To: Subject: Mr.Rae: Tha nk you for your note. Best rega rds, A.S. Fauci ------ > On Feb 25, 2020, at l: 36 PM, James Rae (b)(6) wrote: > > Dear Dr. Fauci> > Thanks for your tv appearance s to educate. > > Cell phone and other touch screens cou ld be a major vector of transmission for Corona virus . > > Please suggest frequent cleaning of devices with alcoho l on your next tv appearance. > > Keep up the good work. I've watched you over the years. Your public education is much appreciated. > > Best regards, > > Jim Rae > Boston area > (b) (6) mobile NIH-001358 From: Date: (b)(6) Tue, 25 Feb 2020 13:09:02 -0500 Emanuel, EzekielJ To: Cc: Subject: (b)(6) Re: lt may well dimin ish somewha t as weather gets warme r. However, there is no guarantee that this will occur. More likely that it will become seasonal and go down in our summer and resurge next winter On Feb 25, 2020, at 12:48 PM, Em anue l, Ezekiel J -------- (b)(6) wro te: To get 1 million deaths of 1957 would requi re 200 million infections at a death rate of 0.5 % . That seems high number of infections . But what is the worldwide seasonal flu death numbers if the USA has 50 ,000 deaths in a bad year and the 1957 number of deaths was 116 ,000 ? The WH O says 650 ,000 death s w orldwid e from seasonal flu. So this could be worse but by about 40 % not an order of magnit ude . Okay so I should be more concerned . And do you think it will go down in late spring with warme r weather? Ezekiel J. Emanuel , M.D., Ph.D . Vice Provost for Global Initiativ es Diane v.S. Levy and Robert M. Levy University Professor ----~~ Chair , Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Dire ctor, Health care Transformation Institute University of Pennsylvania Phone : (b)(6) Fax : 2 15-898-6567 From: Fauci,Anthony (NIH/NIAID) [E] ______ Date: Tuesday, February 25, 2020 12:32 PM To: Emanuel, Ezekiel J (b)(6)> Subject: RE: Zek e: NIH-001359 (b_H _ > (b)( ~ Ari is also calling me frequently . The virus has adapted itself very well to humans with considerable community transmission (certainly in China) now in other countries such as South Korea, Japan, Iran, Italy, etc. If it continues to spread via multiple generations of human to human transmission, then we will not be able to avoid considerable amounts of infect ions and spread in the USA. Seasonal influenza has a mortality of 0.1%. The calculated mortality of COVID-19 to about 2.5 %. It is probably lower since the denominator is likely larger than we appreciate due to asymptomatic infections . Even if the mortality goes down to 0.5%, that is still equivalent to a pandemic influenza of 1957 or 1968. In other words, it could be worse than you think. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E~mail : (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institut e of Allergy and Infectious Diseases (NIAi □) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Emanuel, Ezekiel J Date: Tuesday , February 25, 2020 10:47 AM To: Fauci, Ant hony (NIH/NIAID} [E] Subject: (b) (6) -----~~ (b)(6)> Tony, Ari is pestering me endlessly. What is your latest update and assessment on coronavirus? I still am having a hard time seeing this as serious as everyone else. Am I blind? Yes very transmissible but low mortality like flu in many ways-the elderly , those with comorbidities, and total impact is likely to be less than flu . Also travel restrictions are delaying but not stopping virus. NIH-001360 Am I missing something big or small? Thanks Ezekiel J . Emanuel, M.D ., Ph.D. Vice Provost for Global Initiatives Diane v.S. Levy and Robert M. Levy University Professor - ---~= Chair, Department of Medical Ethics and Health Policy ( 1111 ) -------- Co-Director, Healthca re Transformation Institute University of Pennsylvania Phone: Cb)(6) Fax: 215-898-6567 NIH-00136 1 CbH~ From: (b)(6) Date: Tue, 25 Feb 2020 13:04:40 -0500 Cassetti, Cristina (NIH/NIAID) [E] Fwd: DDP4 Inhibitors and ACE2 Inhibitors :: Spike Protein Bind ing in MERSand To: Subject: SARS Please bandle. Thanks Begin forwarded message: From: JoelMeyer (b) (6) Date: Februar y 25, 2020 at 12:32:24 PM EST To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)( Subject: DDP4 Inhibitors and ACE2 Inhibitors:: Spike Protein Binding in MERS and SARS -------=-c-= Dear Dr. Fauci, Is it possible that DDP4 and ACE2 inhibitors would be effective in preventing coronavirus entry and thereby 'de -rail' the infectious cycle? Thank you fo r your work and guidance to NIAID! Sincerely, Joel R.L. Meyer (b)( (b)(6) ------------------------------------------- https:/ /www .ncbi.nlm.nih.gov/ pmc/articles/ PMC5891363/ "Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERSCoV and SARS-CoV, respectively [1-5]" References 1. Masters , PS., Perlman , S. Coronaviridae in Field 's Virology. Knipe , OM., Howley, PM. , editors. Vol. 1. Lippincott, Williams &Wilk ins; Philadelphia: 2013. p . 825-858. 2. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 ; 88:5209-5212 . [PubMed : 24600003] 3 . De Wit E, van Doremalen N, Falzarano D, Munster VJ . SARS and MERS : recent insights into emergi ng coro naviru ses . Nature Rev Microbiol. 2016; 14:523-534. [PubMed : 27344959] NIH-001362 4. Greenberg SB. Update on human rhinovirus and coronavirus infections. Sem Respir Crit Care Med. 2016 ; 37:555-571 . 5. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016; 16:70-76 . [PubMed : 26855039) NIH-001363 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 13:02:20 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Doctor Radio followup special Please see if this is possible. Thanks Begin forwarded message: From: "Siege l, Marc" < Marc.Si ege l@nyul angone.org> Date: Februa ry 25, 2020 at 12:07: 19 PM EST ------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" Cc: "Conrad , Patricia (NIH/NIAID) [E]" Subject: Doctor Radio followup special (b)(6J: (bH6J > , Beth Ameen Hi Tony Am wonde ring if you might have a few minute s to join us by phone again this Friday between 3 and 4 on coronavirus Would mean alot. Ma rc Sent from my iPhone NIH-001364 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:25:40 +0000 To: Gary Simon Cc: Graham, Barney (NIH/VRC) [E);Ledgerwood, Julie (NIH/NIAID) [E];'Chen, Grace (NIH/NIAID) [E)';Conrad, Patricia (NIH/N IAID) [E);Mascola, John (NIH/VRC) [E) Subject: RE: Coronavirus vaccine From: Date: Tha nks, Garry . I w ill pass you r note on to the peop le w ho wil l be cond uct ing th e phase 1 vaccine tri al here at NIH. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Simon (b)(6)> sent: Tuesday, February 25, 2020 10:42 AM To: Fauci, Anthony (NIH/NIAID) [E)_______ (b)(6) ------~~ Cb _H_6); Fauci, Anthony (NIH/N IAID) [E] Subject: Coronavirus vaccine Dear Tony, samples to NIH for immune assays. gary Gary L. Simon, MD, PhD, MACP Walter G. Ross Profe ssor of Medici ne NIH-001365 Director, Division of Infectious Diseases Vice-Chairman, Department of Medicine (b)(6) F 202 741-2241 Confidentiality Note: Th is e- mail is intended only for the person or entity to which it is addressed and may contain infor mation that is privileged, confidential or otherwise prote cted from disclosure. Dissem inat ion, distri buti on or copying of this e-mail or the informat ion herein by anyone other than the intended recipient, or an employee or agent responsible for delivering the message to the intended rec ipient, is prohibit ed. If you have received this e-mail in error, please call (202) 741-3636 and destroy the original message and all copies. NIH-001366 From: Date: To: Subject: variants Attachments : Fauci, Anthony (NIH/NIAID) [E) Tue, 25 Feb 2020 17:15:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Collaboration proposal on -----------------= ----------------- = (b)(4) Macrogen (Dr. Jeong-sun Seo) letter to Dr. Anthony Fauci.pdf Please handle and res po nd to thi s person. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ogan Gurel, MD (b)(6J> Date: Tuesday, February 25, 2020 9:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> _...;...;...;;.::::====~~-:'.' Cc: Jeongsun Seo MD PhD (b)(6); Changhoon Kim PhD (b)(6); Moon -Young Shin (b)(6) Subject: Collaboration proposal o ------~~ ---------- --------------------- (b)(4 ) Dear Dr. Fauci, Greetings and thank you for all your outstand ing scientific and policy leadership regarding the evolving Covid-19 situation. I am writing to you from South Korea where, as you well know, we are experiencing a very difficult phase of the epidemic. Among t he several groups I have been engaged with to address this crisis, I am work ing w ith the genome sequencing company, Macrogen, w hich you may already be fami liar with (https ://dna.macrogen .com/eng /l . Dr. Jeongsun Seo, the Chairman of Macrogen, along with other company leaders and myself have been discussing (b)(4) (b) (4) NIH-001367 (b) (4) Barring the institution of any extreme travel restrictions, I am planning to visit the Bethesda area next week (Macrogen U.S.HQ is located in Rockville). I know you are extraordinarily busy but if yo u (or key colleagues) have time, I and other senior Macrogen colleagues would be happy to discuss the project, its necessary next steps, along with any other matters related to Korea as you wish. [Please note that I do not have any clinical symptoms or signs of Covid-19 nor any relevant contact history .] Thank you ve ry much for your attention to this matter and I hope that we may have a chance to advance this important project together. Please take care and thanks again, Ogan (b)(6) m:Ihttp ://www .linkedin.com/i n/ ogangurel NIH-001368 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:08:19 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ---------- (b)(6) Let us di scuss. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NEJM content proof (Fauci) Importance: High ------~~ = (b)(6) Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL* of the following instructions and information carefully before you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readabi lity, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections **before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001369 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001370 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001371 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 17:07:30 +0000 Eisinger, Robert (NIH/NIAID) [E];Greg Folkers FW: NEJM content proof {Fauci) N EJMe2002387 _Fauci_ Content2_Author. pdf ----------- (b)(6) Please tak e a look at thi s fo r me and proof to th e extent th at yo u ca n. Thank s. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Laurencot, Elizabeth Date: Tuesday, February 25, 2020 8:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: NEJM content proof (Fauci) Importance: High ------~= Dear Dr Fauci, Attached is the content proof of your editorial. Please read *ALL*of the following instructions and information carefully befor e you begin review ing your proofs. First, please stop and take a moment now to confirm receipt, so that we can be assured that your proofs did not end up in a spam folder. Your editorial has been edited for grammar, consistency, readab ility, adherence to Journal style, and clarity for nonspecialist readers. To expedite publication, we do not ask authors for specific approval of routine changes; please read the entire article to make sure your meaning has been retained . Note that we may be unable to make changes that conflict w ith Journal style or create grammat ical or other problems . Finally, please note that a delayed or incom plete response may delay publication of your editorial. Please read the entire proof carefully, including all queries. Please return your query replies and proof co rrections * * before 12pm (US Eastern) this Friday, February 28, 2020** . NIH-001372 Instructions are provided below . Note that you wi ll be reading for content only; the article will be rendered for print after the content has been finalized . The Journal' s senior medical editors will be reading your article at this stage. If they have any additional comments or queries for you, I wi ll forward them to you in the next few days. TO ANSWERTHE QUERIES: The proof contains in-line numbered query markers and a numbered list of queries at the end . The query markers and the queries are linked, so you can jump back and forth within the file . Please respond to all the queries (see below for instructions ; please do ** NOT** use eannotation too ls) and convey any additional changes as needed . TO RESPOND BY E-MAIL: If your corrections and your responses to the queries are straightforward, we encourage you to respond by replying to this message. Please copy and paste the list of queries into an e-mail message or a Word document and type your responses there. You may also include a list of changes (e.g., page 1, line 20, change xxx to yyy). Again, please do ** NOT** use e-annotation tools in the PDFfile; the marks are small and easy to miss, which may lead to errors in your article . Please note that this material is confidential and embargoed until publication. If you have questions about our embargo policy, please contact NEJM Media Relations at 781-434-7847 or at Med iasupport@nejm.org . Again, please do confirm receipt at this time . Thank you very much for your efforts with these content proofs! Best, Eli Elizabeth Lauren~ot Senior Manuscript Editor New England Journal of Medicine 617-487 -6547 elaurencot@nejm .org TO READ THE PROOF: You will need Adobe Acrobat Reader software (version 4.0 or later) to view this file . Acrobat Reader is available free of charge at the Adobe Web site (http://www .adobe.com/products/acrobat/readerma in.htm l ). NIH-001373 This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privi leged, and/or proprietary material. Any review, duplication, retransmission, distribution, or ot her use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-001374 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 15:55:19 +0000 Barasch, Kimberly (NIH/NIAID) [C] FW: The global health leaders call, Wednesday 26 February at 13:00 CET (b)(4)Swisscom Call code.pdf To: Subject: Attachments : Please print out for tomorrow AM. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: RYAN, Michael J. Date: Tuesday, February 25, 2020 4:10 AM To: Redfield, Robert R. (CDC/OD)--------------------~~ ------- (b)(6) Chris.Elias (b)(6); Jeremy Farrar ===================-~ Cb)(6) Fauci, Anthony (b)(6) Conrad, Patricia (NIH/NIAID) [E] (b)(6) ------- >; Lynn Banks __________________ (b)(6); Presiden t I Resolve to Save Lives Cb _)_(6) Tarik Mohammed Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. CbH6l>;MAHJOUR, Jaouad (b)( ·>; FALL, lbra hima Soce (b)( >; GREIN, Thomas (b)(6); MI NHAS, Raman (b)(6):>; COX, Paul Michael (b)(6); AL-SHORBAJI,Farah CbH6J .>; POOLE,Marcia (b)(6) ·>; DRURY,Patrick Anthony (b)(6J,.> ; GRAAFF,Peter Jan (b)( ; Dr VAN KERKHOVE,Mar ia (b)(6J:>; KABIR, Sophia ------------ ::=====~~ ------- NIH-001375 (b)(6) Subject: The global health leaders call, Wednesday 26 February at 13:00 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus . The teleconference will be hosted tomorrow Wednesday, 26 February at 13:00 CETand the dial- in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email: (b)(6); mobi le no. (b)(6) -----Best, Mike NIH-001376 From: (b)(6) Date: To: Subject: Tue, 25 Feb 2020 07:30:31 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Bloomberg Radio 2/25 Let us discuss Begin forwarded message: From: "Jameelah D Robinson (BLOOMBERG / NEWSROOM:)" Date: February 25, 2020 at 7:25:43 AM EST To: "NIAID NEWS (NIH/NIAID)" Cc: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) 1. Subject: Bloomberg Radio 2/25 Reply-To: "Jameelah D Robinson" Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene , Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah NIH-001377 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:27:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: NIAF and coronavirus Let us discuss. From: Elvis Oxley Date: Monday, February 24, 2020 9:42 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Eric Jia-Sobota Subject: NIAF and coronavirus (b-c)(c= 6) Dr. Fauci, I trust this email f inds you well. It has been a few years since we've seen one another on the Hill or at a NIAF event but hopefully we will rectify that soon. I know you have a lot on your plat e, especially with the coronavirus, but I am curious if you have five minutes for a call tomorrow so I can introduce you to my boss at BDO, Eric Jia-Soboda (https://www.linkedin .com/in/ eric-jia-sobota -02156036/ ). Eric is an expert in cost accounting for Life Sciences companies and he wants to glean your perspect ive on the likely structure of the emergency coronavi rus budget request so that NIH and others can maximize those research and implementation dollars at the most rapid pace. We would certainly appreciate your time. My best, Elvis ElvisOxley Managing Director Industry Specialty Services (b)(6)(Mobile) 703-245-8665 (Direct ) eoxley@bdo.com ----- BOO Greater Washington D.C. 8401 Greensboro Drive, Suite 800 McLean, VA 22102 www .bdo.com BDO USA, LLP,a Delaware limited liability partnership, is the U.S. member of BDO International Limited, a UK company limited by guarantee , and forms part of the international BDO network of independent member firms. BDO is the brand name for the BDO network and for each of the BDO Member Firms. IMPORTANT NOTICES The contents of this email and any attachments to it may contain privileged and confidential information from NIH-001383 BOO USA, LLP.This information is only for the viewing or use of the intended recipient. If you are not the intended recipient, you are hereby notified that any disclosure, copying, distribution or use ot or the taking of any action in reliance upon, the information contained in this e-mail, or any of the attachments to this e-mail, is strictly prohibited and that this e-mail and all of the attachments to this e-mail, if any, must be immediately returned to BOO USA, LLPor destroyed and, in either case, this e-mail and all attachments to this e-mail must be immediately deleted from your computer without making any copies hereof. If you have received this e-mail in error, please notify BOO USA, LLPby e-mail immediately. NIH-001384 Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 03:26:06 +0000 Tabak, Lawrence (NIH/OD) [E) RE: Close of Day Note for 2/24/2020 re: coronavirus preparedness From: Date: To: Subject: No, I did not see this. You should tell Jim Gillman to copy me on everything that relates to this issue since I am the one who will be dealing with the Congress, the President and the press about all of this. ---------------,;-, = From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 9:4 1 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) (b)(6)> Subject: FW: Close of Day Note for 2/24/2020 re: coronavirus preparedness Tony, I assume you have already seen this, but just in case.... Larry From: "Gilman, James (NIH/CC/OD) [E]" Date: Monday , February 24, 2020 at 5:50 PM --------~~ To: "Tabak, Lawrence (NIH/OD) [El" -------Subject: CbH6),"Gottesman, CbH6)> CbH >, Francis Collins Michael (NIH/OD) [El" Close of Day Note for 2/24/2020 CbH > re : coronavirus preparedness Francis/ Larry/ Michael: (b)(5) NIH-001385 (b) (5) Jim NIH-001386 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 23:38:09 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: LA Magazine/ Interv iew request Let us discuss. From: jmcgahan (b) (6l Date: Monday, February 24, 2020 6:03 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: LA Magazine/ Interview request ::;..,..-,= (b)(6)1> Dear Dr. Fauci, You and I haven't met. I'm a long-time wr iter for Los Angeles Magazine. We're doing a cover story for the April issue on the threat of the new coronavirus poses to the 10 mill ion inhabitants of metropolitan Los Angeles. Would you be available for an interview on Wednesday? Thanks, Jason NIH-001387 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 22:42:57 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Welcome packet & consent form From: Date: To: Subject: COVID-19 I Forum Att achments: room agenda .pdf I The Coronavirus Outbreak: Tracking 3.2.20 Consent form .pdf, 3.2.20 Forum welcome document .pdf, 3.2.20 Green Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Dweck, Kristen Date: Monday, February 24, 2020 5:34 PM To: Yip, Winnie Chi-Man Cc: (b)(6)Osborn, Elizabeth (b)(6) Lipsitch, Marc (b)(6) ----:----========~~-----""-""".""".---:-:=======~ >; Fauci, Anthony {NIH/NIAID) [E] _______ Cb _ H_6) ,;.. (N _I_ H;/_N_IA _ I_D.:.. ) .:... [E~) ===~:--:--:-:-- (b)(6) ; ..( N - 1-H-/:-N- IA _ I... D~) ".""' [E~) ===~:.:..._-- (b)(6)>; Conrad, Patricia Barasch, Kimberly (NIH/N IAID) Folkers, Greg (NIH/NIAID) [E] --------- (b _ )~(6)>; [CJ (b)(6) •>; Lerner, Andrea (b ~)~(6) Subject: Welcome packet & consent form Imp ort ance : High I The Coronavirus Outbreak : Tracking COVID-19 I Forum Good evening , Please find attached , The Forum welcome document , green room agenda and consent form . The welcom e packet includes information about our production along with what to wear while on camera. The Harv ard T.H. Chan School of Public Health consent form is required for productio n ofwebcast series. Please sign and scan a copy of the consent fonn back by March 2, 202 0. We look forward to an excit ing event! NIH-001388 Best, Kristen Dweck Kristen A. Dweck Digital Media and Engagement Manager, The Leadership Studio Harvard T.H. Chan School of Public Health 677 Huntingto n Avenue, Kresge 329 I Boston, MA 02115 o: 617-432-1268 I f: 617-432-1780 kdweck@hsph.harvard .edu ~ HARVARD ~ T.H.CHAN SCHOOL OF PUBLICHEALTH Join the conversation: The Forum I Twitter I YouTube I iPhone and iPad NIH-001389 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 22:34:05 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Re:Following up on NIH visit Date: To: Subj ect : W hat is t his? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 4:04 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)( 6) ; Hoffman, Hillary (NIH/NIAID) [El ------- (b) (6) > -------- Cc: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --=~ (b)(6) Seg re, Julie (NIH/NHGRI) [El Subject: RE: Re:Following up on NIH visit Dear Hillary , Thanks for you r email . I a m in de e d l st ill h opi n g app re ciate he back when we Warm regards ooki n g forward t o my NIH v isi t I migh t ge t some t ime wi t h Dr . might be b usie r than either of firs t sc he du le d my in t er v iew wi , Jason Jason Gale, MHlthSec Senior editor I Bloomberg News Level 30, 120 Collins St., Melbourne VIC 3000 NIH-001390 on F r i day, a nd am Fauc i, t h ough I ca n us expected to be t h him! Tel. (landline ) +61-3-9228-8783 I Mobile CbH6) @jwgale I Linkedin : http://www .linkedin .com/pub/jason-ga le/6/249/a56 F r o m: (b)(6) At : 02 / 2 5 /20 To ; Jaso n Ga l e (BLOOMBERG/ NEWSROOM ; ) Subjec t : RE: Re :F o ll owin g up o n NIH v i s i t 06 : 4 7 : 17 Hi Jason , Hope you have/had safe travels to DC this week ! I wanted to check in to confirm that you 're still planning on coming to visit us at NIH this Friday? Currently , Dr. Myles is holding 10am and Dr. Belkaid is holding 1:30pm to discuss their microbiome-related research with you. Dr. Fauci's schedule has been very fluid lately due to the coronavirus outbreak-we 'll likely need to check in with his assistant Patty Conrad on Thursday to see how his Friday calendar looks (unless you hear otherwise from Patty directly). Best, Hillary Hillary Hoffman, Ph.D. , Writer/Editor Office of Communications and Government Relations , NIAID , NIH 5601 Fishers Lane #6G38 Rockville , MD 20852 (b)(6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Tuesday , January 28, 2020 4:39 PM To: Hoffman , Hillary (NIH/NIAID) [E] CbH6)> Subject: RE: Re:Following up on NIH visit --------=-:= Sounds good . Many thanks. ----- Original Message ----------From: Hillary Hoffman To: JASON GALE At: 29-Jan-2020 08:38:46 ---------- Sounds good - I'll ask Dr. Myles to hold 1Oam, so you can chat with him before you meet Dr. Fauci at 11. We can re-confirm timing closer to the date. I'll tag along , and can make sure you get where you need to - you'll get to visit several different buildings, fortunately all close by! NIH-001391 From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Tuesday, January 28, 2020 4:32 PM To: Hoffman, Hillary (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit ------- -------= J> (bH 6 Hi Hillary Late night for me on 2019-nCoV ... Shall we say before DrFauci? Then I'll know better how to get to him. ~ Thank s a lot. Jason ________ ----- Original Message------------~= From: Hillary Hoffman ,__ To: JASON GALE CC: (b)(6) At: 29-Jan-2020 06:34:55 (b)( _, Hi Jason , Great speaking with you last week. I wanted to follow up to let you know that Yasmine Belkaid and Ian Myles-whose work we discussed on host-microbe interactions and developing a bacteria-based treatment for eczema, respectively-are willing to meet with you on Feb. 28. Here are links to some background info: • Dr. Belkaid's lab page , and recent NIA ID press release about a skin microbiome study from her lab • Dr. Myles' lab page, and NIA ID press release about findings from a Ph 1/2 trial assessing the R. mucosa treatment for eczema Dr. Belkaid is available at 1:30pm (her building is next to the Clinical Center, where you'll be meeting with Julie Segre I believe from 12-1ish). Dr. Myles' schedule is a bit more flexible, and he's currently available to meet either in the morning before you speak with Dr. Fauci or later in the afternoon after Dr. Belkaid (Dr. Myles is in the Clinical Center, about a 5 min walk from Dr. Fauci's building)- let me know if you have a timing preference. We can firm up times a bit closer to the date, but wanted to give you an update. NIH-001392 Best, Hillary Hillary Hoffman , Ph.D., Writer/Editor Office of Communications and Government Relations, NIAID , NIH 5601 Fishers Lane #6G38 Rockville, MD 20852 (b)( 6) (b)(6) From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Thursday , January 23, 2020 4:09 PM To: Hoffman , Hillary (NIH /NIAID ) [E] Cc: Routh, Jennifer (NIH/NIAID) [E] Subject: RE: Re:Following up on NIH visit Sorr y!! Ge t t ing on no w From: 01/ 24 /20 (b)(6) -------------08 : 07 : 4 8 At: To: J aso n Ga l e (BLOOMB ERG/ NEWSROOM : Cc: ( Subject Cb)(~ : RE: Re : Following up on NIH visit Hi Jason , Wanted to check that you're still able to join us this afternoon/morning -- and that you aren't having issues calling into the conference line. Jen and I are both on. Thanks , and hope to talk soon! Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM :) Date: Friday , January 17, 2020 3:02 PM To: Hoffman, Hillary NIH/NIAID) [E] (b)( 6) Cc: Routh, Jennifer (NIH/NIAID) [E] NIH-001393 (b)(6 )> Subject: RE: Re:Following up on NIH visit Awesome. Thanks a lot. ----- Original Message----From: Hillary Hoffman (b)(6) To: JASON GALE cc (b) (6) At: 18-Jan-2020 01 :31 :40 Hi Jason , Yes , 4pm next Thursday (8am Friday for you) works for us. I will send out a calendar invitation with call-in information later today. Enjoy your time off, and looking forward to speaking with you next week! Best, Hillary From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Thursday , January 16, 2020 6:24 PM To: Hoffman , Hillary (NIH/NIAID) [E] (b)(6)> Cc: Routh, Jennifer NIH/NIAID [E] '---,;- (b=H =6)> Subject: RE: Re:Following up on NIH visit Dear Hillar y, Than ks for your email . I am on vaca t ion Mon- NIH-001394 Thursday next week . Woul d a 4 pm call on Thur sday Jan . 23 (8 am Friday for me) work? I jus t saw ha p pened t o see this report , FYI : h ttp s : //med i ca l xpr ess . c om/news/2020 - 01 - gu t bacter i a park inson . h t ml ?fbc lid = I wAR20XNzDroX9za HhP 73A22 pK2zOP 2 cR Q6 YJ j dQo ic bKrNKr j oPrQ9Z0 I t' s a good exam p le of t he growing awareness that the Human Micro b iome Project is hel p ing t o p rovide of the complex int erac tions with various b iological processes that un derp in health and disease. Have a grea t weekend , jason From: (b)(6) At: 01/17/20 03 : 22 : 49 To: Jaso n Ga le (BLOOM BERG/ NEWSROOM : Cc: (b)(6) Subject: RE : Re:Following up on NIH visit Hi Jason, Great to hear of yourinterest in microbiomeand flu research. Jen and I would be happy to chat about what NIAID may be able NIH-001395 to offer in terms of subjec t matter exp erts and storylines in those areas. Might you be available for a short call next week between 4 -5pm EST on either Tues., Wed ., or Thurs . afternoon corresponding to 89am Melbourne time on Wed., Thurs. , or Fri. morning (assuming I've got my time zones correct)? If we can 't find a mutually convenient time , happy to continue discussions over email. Best , Hilla ry Hillary Hoffman, Ph.D., Write r/Editor Office of Communications and Government Relations, NIAID, NIH (b)(6) Media line : 301-402 1663 From: Jason Gale (BLOOMBERG / NEWSROOM :) Date: Wednesday, NIH-001396 January 15, 2020 11:56 PM To: Rancourt , Anne (NIH/NIAID) [E] (b)(6) Cc: Leitman , Laura (NIH/NIAID) [E] )(6) Hoffman , Hilla ry (NIH/NIAID) [E] (b)(6) ; Routh, Jennifer (NIH/NIAID) [E] (b)(6) Lave lle, Judi th (NIH/NIAID) [El (b)(6) Segre, Julie (NIH/NHGRI) [E] )(6) Subject: RE: Re :Following up on NIH visit Hi Anne, Thanks a lo t for yo ur ema il a nd your sugges t ions! After my last vi sit to NIH ( a nd mee t in g with Lisa Pr octor and J u l ie Segre yea r s ago }, we d i d t he attac he d s to r y on the gu t mic r obiome . We ' r e ve ry keen t o l oo k NIH-001397 at do in g a podcast ser ies on the microbiome (skin, gut , other anatomical b i ts ) a nd ho w it ' s informing our views on he a l t h, disease and the way we prevent a nd treat diseases . It would be coo l t o works ho p t hi s theme with you a nd your co ll eagues before my v i s i t , if you h ave some t ime? I cut my teeth in medica l sc ien ce writing on (bird) fl u and wou l d be interested in the re search Jeffrey Taubenberger 's lab is doing , but my un derstanding (and I could be wro ng) i s t h at t he re ' s still a lot of work to be done in producing a universa l flu NIH-001398 s h ot . I f suc h vacc in e candidates are st ill y e ars fro m en t e r in g clinical trials , we probab l y wou l d p u sh that lower down the list . Hop e t h at helps , and thanks again ! Jaso n Hi Jaso n, Ahead of yo u r visit , here are a f e w l abs that are doing innovative work a nd may present interesting backgrou nds t o become f u t u re stories , or in for m your report in g . For antimicrobial res i stance spec i f i ca ll y , Dr . Fa u ci is your best source . Bu t the below are exci t in g areas of researc h at NIAID , and may be a f i t for Prog n os i s . Le t me know if any of the below p i que your NIH-001399 in t eres t a n d we ca n s h are more detail a n d/or arrange time . • Skin microbiom e: NI AI D researc he rs deve l oped a t op i ca l therap y for eczem a that in vo l ves tr ea t in g skin with "goo d " bacter i a . If proven effective , t hi s strategy co ul d offer an inexpensi ve tr ea t men t that req u ires l ess frequen t applicati on t h an many c u rrent eczema medica t i o ns . A Phase 1 /2 tr i a l at NIH in d i cated NIH-001400 t h at t his no ve l therapy i s safe , a nd mos t participa nts experienc ed imp r oveme n ts in their eczema . NI H h as excl u sive ly l i ce n sed the technolo g y to Fo rte Bioscienc es t o adva n ce this pote n t i a l ne w therapy t h roug h fur t he r clinical deve l opme nt . • Gene therapy: NI AI D is developin g a nd app l y in g gene corr e ct i o n techniq u e s to tr ea t a NIH-001401 var ie ty of g enetic immune d i sord e rs . For example , NI AI D scientist s co deve l oped a lentivira l gene therapy to treat inf a n ts with XSCID , a rar e a n d fa ta l genetic immune d efi c ien c y . In c l ini ca l tr i a l s , the g ene t he rapy s uc cessfu lly restored t he immune systems of infants newly d i agnosed with XSCID , as we ll as olde r children a nd you n g adu l ts with the NIH-001402 co n d i t i o n wh o experienc ed comp l ex medical problems after receiving standard t h erapy . Mu stang Bio is h and l i ng commercia l deve l opme nt of the lentivira l ge n e t h erapy for XSCI D. • Flu: Dr . Jeffrey Taube nber ger is a 1918 in f l ue n za expert who sequenced the 1918 pandemic v i ra l ge n ome u sing arc hi va l autopsy specimens from t h e Armed Forces I n stitute of NIH-001403 Pa t holog y a nd frozen l ung b io ps ie s from 1918 fl u v i ct im s interred in permafros t . Lear ning about 1918 pandemic f l u ca n help us better prepare for a n d target fu t u re pa ndem i c strains . Dr . Taubenber ge r ' s lab is deve l op in g a so ca ll ed universa l fl u vaccine t h at incl udes 4 in act i vat ed infl u enza v i ruses and is expected to undergo clinical NIH-001404 t es t in g soo n. Also , Dr . Matt h ew Memoli l e ads NIAI D' s in f l ue n za challenge st u dies in whi c h healthy vol u ntee r s are pu rp os e ly exposed to infl u enza in a carefu ll y co n t ro l l e d e nv i ronme nt . Challenge stud i es offer a u niq u e oppor t u ni ty t o ask foc u sed q ues t i ons regard in g infl u enza vi r u s pat h oge n e sis and vaccine e ff i cacy in a cont r ol le d mann er . • Mosquitoe s: NI AI D' s NIH-001405 Laborator y of Malaria a nd Vector Research investiga tes disease transmitt ing insects and broad areas of malaria biology and pathogene sis . Dr . Tov i Le hma n st udies mosqui t o eco l ogy, covering broad popu l at io n biology questio ns re l evant to patterns of malaria transmiss ion a nd vector control . Recent l y , Dr . Le hman a nd colleague sin Mali found t h at a single NIH-001406 mosqu i t o ca n tra v el u p t o 2 00 mi l e s in a sin g le ni g ht wi t h t he ri g ht prevaili n g win d speed . Th e re s e a rc h involved collect in g f l y in g i n sects u sing s t i cky ne t s on h eli umfi ll ed ba ll oo n s s u spended at vary in g h e i g hts . • Eating for the immune system: Dr . Yasmin Be l ka i d is researc hi ng co nne c t i o ns b e t ween t he mic r obiom ~, nu t r i t i o n NIH-001407 , f at , a nd immunity . Thi s work is e ar l y stage , b ut pot en t i a l ly paradi gmshif t ing as she uncov ers co nnec t io ns bet ween d ie t a nd immunity , with im p l i cat i ons fo r us in g nu tr i t ion t o boos t immune in t erven t ion s , including vacc ine s . • RSV: Multiple r ese arc he rs are workin g to deve l op vaccines aga in st resp i rato ry sy n cyt i a l v i rus (RSV) so met hin g most NIH-001408 pare n t s h ave heard of , bu t i s no t covered by media . RSV u s u ally ca u ses mi l d cold - like symptoms in healthy ad u lts ; h owever , RSV can be s e r i ous , part i cu l a rly for in fa n ts a nd t h e elderly . I t i s t he mos t common cause of bro n c hi o l itis and pneumon i a in children yo u nger t h a n 1 in the US . Scientist s h ave spent decades try in g t o develop an urge n t l y n eeded safe and NIH-001409 effec t i ve vacci ne. One ca nd i date kn own as DS- Cavl developed by Dr . Barney Graham ' s t eam at NIAID ' s Vaccine Researc h Center has shown ear l y promise in a Ph as e 1 c li ni ca l trial . I' m CCin g my pub li c affa i rs colleagues who li aise wi t h t he se top i cs in case there i s fo ll ow up . Look in g forward to hopef u lly mee t in g you when you visit . Thanks , Anne From: Jason Gale (BLOOMBERG/ NEWSROOM :) NIH-001410 Date: Thursday , December 19 , 20 1 9 4 : 24 PM To: Ra n court , Anne (NIH/NIAID ) [ E] )(6) > Subject: Re : Followin up g on NIH visit Hi Anne , Tha nks for your ema il a nd offer to ass i s t wi t h o t h er in t e rv ie ws . I ' m "old sch ool ," and s ee mer i t in b u ilding relationships wi t h researchers and hearin g about t hei r work wi t hou t t he e xpec tat i o n of n ecessar il y g ettin g a sto r y . My interests ar e pr e tty eclectic -- from a nt imi crob i a l resistance to NIH-001411 a nes t hesi a . I f t he r e ' s some interesting stuff h appe nin g t h at hasn ' t been reported on in muc h d e ta il that speaks to t h e futu re of he a l t h care (that co ul d would fo r ou r Prog n os i s platform) , I 'd be keen t o hea r abo u t it . Ma n y t h a n ks aga in a n d happy holidays, Jason l Ut 01 T l . (1 . lJ.. "" (b)(6) l _ J.. l . - ·.<.l l I h t t p : //www . l i n kedin . com/p u b/ jaso n g ale/6/2 4 9/a56 NIH-0014 12 F rom : )(6) At : 1 2 / 20 / 1 9 0 2 : 54 : 3 0 To: Jaso n Ga l e (BLOOMBERG/ NEWSROOM : ) Subj e ct : Fo l low in g u p on NI H visit Hi J ason , I he a r d you ' ll be vi s i t i ng us a t NIH on Feb . 2 8 fo r an inte r v i ew wi t h Dr . Fa uci . Please le t me know if I can he l p connec t you with o t her e xp er t s whil e y ou are NIH-001413 here . I 'd be h appy to arrang e for you t o see a ny l abs or he ar from expert so n HIV or other d ise as es ju st let me k no w what you 're in t ere ste d in he ar in g and seeing Thanks Loo k in g forwar d to i t. Anne Anne Rancou rt, MPS Sec t io n NIH-001414 Chief , Office of Commun icatio ns and Govern ment Relati ons Nat ion al Ins t i t u t e of Allerg y and Infe c t ious Diseas es Nat ion al Instit u t es of Hea l t h Pronou ns : She/He r (b)(6) office (b)(6) mob ile (b)( 6) NIH-001415 Madonna 's Secret for Longevity Seen Aiding Bacteria Boom: Health 2012-05-08 21 :34:07 .963 GMT By Kaneko Matsuyama and Jason Gale May 9 (Bloomberg) -- The secret to Madonna's staying power may be surprisingly simple: gardening. What the pop star does involves no trowel or soil. Thanks to dishes of fermented soy beans , millet and brown rice prepared by her personal chef, Mayumi Nishimura , Madonna practices a form of inner horticulture -- cultivating her intestinal flora in a burgeoning alternative approach to health . Studies of the trillions of bacteria living on and in the body suggest the Material Girl , 53, may be onto something. By eating foods rich in fiber and laced with so-called good NIH-001416 bacteria , she may be encouraging helpful microbes to flourish in her bowel, aiding in food digestion and vitamin extraction and possibly staving off diseases from asthma to colon cancer . "This diet that Madonna is following is very sensible, " says David Topping, chief foodnutrition researcher at Australia's Commonwealth Scientific and Industrial Research Organization in Adelaide, who studied gut biology for 25 years . "The bacteria that live inside you are fulfilling very important functions ." While scientists try to understand the ecology of the bacteria and their interactions with diet and disease , companies are looking for ways to profit. The health benefits of gut germs have spawned a global market for products NIH-001417 that contain friendly bacteria , called probiotics , in the form of tablets or supplements added to foods by companies including Danone , Nestle SA, and Yakult Honsha Co. The market for supplemented dairy products such as Danone's Activia yoghurts and Yakult's fermented drinks , worth $14 .7 billion six years ago, will probably expand 32 percent to $33.5 billion by 2016 , Euromonitor International estimated last month. Quinoa, Not Coffee Studies published in the past year have linked certain bowel-dwelling bacteria to a stronger immune system , while others have been associated with autism and obesity. In one paper published in the journal Nature, scientists showed that a type of white blood NIH-001418 cell that produces antibodies only acquired its infection-fighting ability after spending time in the gut. Nishimura, who has cooked for cancer patients before being hired by Madonna , serves quinoa and other whole grains as staples , along with vegetables and soy sauce, she said in a telephone interview from New York. She also tries to offer seaweed every second day -usually sauteed or boiled. "We eat food processed as little as possible ," Nishimura, 55 , says of her dietary approach , known as macrobiotic. She doesn't recommend meat, dairy and coffee. An agent for Madonna didn't respond to a request for comment. Whole grains and fiber act as both food and fertilizer to the bacteria in the bowel, according to Mark Morrison , a NIH-001419 microbiologist with Australia's CSIRO in Brisbane studying ways to improve gut function and health. 'Terrific Interest' There are 10 times as many bacteria in the human intestinal tract as there are cells in the body. As coordinator of the Human Microbiome Project, Lita Proctor is helping to organize collaboration from hundreds of scientists around the world trying to map and study microbial communities living on the skin , in the mouth and bowel, and in other parts of the body. "It's extremely heartening and healthy to have so much attention now paid to the diet ," says Proctor, who works at the National Human Genome Institute in Bethesda, Maryland . Even so, Proctor says the research is still in its infancy, and products based NIH-001420 on partial understanding may not deliver what they promise . "That's not holding up the industry ," she says. "It's a very fluid , ill-defined area , but with a lot of terrific interest." Flowers and Weeds The term probiotic is vague and there's no accepted definition for it. Measuring results may be even more of a grey area and some supplements are destroyed by stomach acid before entering the gut , according to Proctor. Nishimura relies on fermented foods such as miso, soy sauce and tempeh to play the role of probiotics and says the benefits of her diet can be quickly noticed. "I feel better than I did 20 years ago," Madonna wrote in a preface to the cookbook her chef had published in 2010. "I am NIH-001421 very grateful to you for this." The garden analogy is helpful when it comes to describing the complex ecology of the bacteria living on humans, says Julie Segre, the lead investigator working on the skin microbiome at the National Human Genome Research Institute. "There are some flowers that make it easier for other flowers to grow in the same soil," Segre says. The most important thing is to keep out the invasive weeds, she says. 'Transpoosions ' When the weeds take over , Australian gastroenterologist Thomas Borody has a radical approach to reestablishing the balance of intestinal flora in his patients: he transplants fecal germs from disease-free individuals directly into the upper reach of the colon , in a pouch NIH-001422 known as the cecum. His Sydney clinic has done 1,800 of the procedures , which he jokingly dubs "transpoosions ," over 25 years. Borody , 62 , says the treatment has helped patients with ailments ranging from autism to pseudomembranou s colitis, a resilient infection that causes abdominal pain, loose bowel movements and fever. "The next day their diarrhea stops, " the doctor says . After the procedure , he asks patients to avoid treatments that may damage their gut flora. Three studies presented at the American College of Gastroenterology 's meeting in October indicate fecal transplants can help with bouts of diarrhea associated with the bacterium Clostridium difficile. NIH-001423 When Weeds Take Over Keeping inner bugs healthy is crucial because otherwise they risk taking over more than the garden . If intestinal bacteria aren't able to survive on the food their host consumes , the germs will try to feed on what they can find -- "mucus as well as anything else ," according to CSIRO 's Topping. That may lead to inflammatory bowel disease, a painful condition that can evolve into colon cancer , he says . Staving off disease is one reason people have turned to Nishimura 's cooking in the past. The chef, who prepared meals for cancer patients in Boston, says the diet helps with constipation, menstrual pain and body odor . When she first changed the way she ate, Nishimura says she also found that her NIH-001424 allergic skin rash improved . 'So Fresh ' Typically, Nishimura tailors her meals each day to suit the way her employer feels , she says, adding that Madonna prefers the chef herself to shop for ingredients. Popular dishes include seaweed in miso soup ; hijiki -- a type of brown seaweed served with carrots and onions and seasoned with soy sauce; and cooked oats for breakfast , Nishimura says . Whole grains demand harder work for bowel bacteria , which help the body extract vitamins and nutrients from food, because the insoluble fiber they contain is only broken down in the lower reaches of the digestive tract in a fermentation process that delivers different quantities and varieties of inflammation - NIH-001425 fighting short-chain fatty acids to the body's cells. There is "solid evidence" that microbes play a role in tuning the immune system , says Ian Lipkin, director of the Center for Infection and Immunity at Columbia University 's Mailman School of Public Health, where scientists showed in January that children with autism and gastrointestinal disturbances have a bacterial species not found in nonautistic children with tummy upsets. Madonna and others making similar diet choices may not know they 're pushing the science frontier. They may just feel better. "When you cut out animal products, white sugar and coffee for 10 days you start to feel the difference ," Nishimura said. "When I first began NIH-001426 this diet, I remember how my head became clearer, I woke up earlier and felt so fresh in the morning that I didn 't want to stay in bed." Madonna herself isn't lacking in stamina . Her world tour , which starts in Tel Aviv this month and ends next March , includes 75 concerts in Europe and North America . Her previous world tour was in 2008 and 2009 , when she also published six children's books and directed or produced two movies . For Related News and Information: Most-read healthcare stories : MNI HEA Bloomberg 's top health stories: HTOP Bloomberg 's top stories on Japan: TOPY Bloomberg drug database: BORG --Editors: Marthe Fourcade, Rick NIH-001427 Schine. To contact the reporters responsible for this story : Kanoko Matsuyama in Tokyo at +81-33201-3490 or kmatsuyama2@b lo om berg .net; Jason Gale in Melbourne at CbH6) or j .ga le@bloomberg .n et To contact the editor responsible for this story : Jason Gale at +656212-1579 or j.gale@bloomberg .n et. NIH-001428 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 22:33:02 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Virus Transmission Date: To: Subject: NIAID inquiries, please Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: DANIEL GAGNON Date: Monday , February 24 , 2020 3:49 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Virus Transmission ---------------~~ (b) (6) -------- (b)(6) > Hi Dr. Fauci: 1 have been a long time admire r of you in the field of modern medicine. This question l have relates to the current Coronavirus circulating around the world. For many years r have informed people that the ways a virus can be passed from person to person isn' t always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medical community though t that if someone were smoki ng and was an infec ted person that once they expel the smoke particles into the air that those micro s moke panicles may contain viruse s that were in the respiratory system ofan infected perso n. Everyone T mention this to don ' t believe that this is poss ible. Whal are your thoughts on this matter? lfso why hasn' t tbe medica l comm unity warned the public about this possibility as T stay away from all establis hments that allow smok ing on their prem ises . Thank you, Daniel Gagnon (b)(6) NIH-00142 9 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 19:55:2 1 +0000 Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] FW: interv iew with Dr Fauci From: Date: To: Subject: Here is th e reason for t he con f usion ., Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: RABIN, RONI Date: Monday, February 24, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: interv iew with Dr Fauci ------~~ -------- Cb)( > I 'm sorry -- I thought you had canceled this time this morning when you said you needed to reschedule. I'm so sorry . I'm in the middle of a meeting with editors at the Times about coronavirus coverage. On Mon, Feb 24, 2020 at 2:42 PM Fauci, Anthony (NIH/NIAID) [E] -------- CbH6)>wrote: Hi Roni, We just tried calling you a_ t !:::::==~ (b =-)~(6) :- for our 2:30pm ET interview w ith Dr. Fauci. Please give us a call as soon as possible at (b)(6) _ Thank you, Kim Kim Bara sch [CJ Office of the Directo r Nati onal Inst itu te of Allergy & Infe ct ious Diseases (b)(6) (b)(6) NIH-001433 From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:30 PM To: (b)(6) Cc: Deatrick, Elizabeth (NIH/NIAID) [CJ (b)(6)> Subject: interview wi t h Dr Fauci (CJ ----------- CbH ; Robinson, Whitney (NIH/N IAID) Dr Fauci can be available for your interview as per below on Monday Feb 24t h at 2:30 pm ET- 3:00 pm ET. Please let us know asap if that time works. The number to call for the interview will be (b'll - (6) Thank you, -patty Roni Rabin New York Times (b)(6) Roni.rabin@nyt imes.com Seeking: Phone interview Subject: asymptomatic transmission of coronavirus Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The Nationa l Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Discla imer: The informat ion in this e-mail and any of its attachments is confiden lia l and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. Roni Caryn Rabin New York Ti mes Staff Writer (212) 556-8314 NIH-001434 ----- Cell: (b)(6) NIH-001435 From: Date: To: Subject: Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 18:07:33 +0000 Doepel, Laurie (NIH/NIAID) [E] FW: ASF---- measles - aerosol / contact/ drople t 1-s2.0-51879625717301773-main.pdf From: Folkers, Greg {NIH/N IAID) [El (b)(6) Se nt: Tuesday, September 4, 2018 3:15 PM To: Fauci, Anthony (NIH/NIAID) [E]-----=(b)""'~= > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( 6); Doepel, Laurie (NIH/NIAID) [El Cb)( ; Eisinger, Robert (NIH/NIAID) [E] Cb H6J Folkers, Greg ~-':'""'."'.'"'.""'.""-:-:~ ;::::::==:::::.;_.....;;;.___; -..-.--.= (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/N IAID) [E] (b)( 6) Subjec t : ASF ---- measles - aerosol /contact/ droplet And per CDC -- rrequ ires airbornes precautions http s://www .cdc.gov/infect ionco ntrol/ba sics/tran smission-based-precaution s.htm l Table2 Ovel'lliew of the evide nce on trans mission routes of respiratory viruses based on expe rim ent al data and the transmi ssion route acco rding to infec tion prevention guidelin es V1rus Virus family" Transmission route Guidelines Expe-imental and observational data Measles virus Paramyxoviridas Aerosol [75-n ,78° ,79"]. Parainfluenza virus Paramyxovirfdas Limited data, contact (by fom ite) [83,841 ". HMPV RSV Pnevmoviridae Pnevmoviridae Limited data. c on tact (by fomite) " (30] Contact [89 .88] , ci'up let (88], ae rosol HCoV Coronaviridae Umited data , contact (by fomite) [~6 7] MERS-CoV Coronavlridae SAAS,CoV Coronaviridae Contact (84 ) • [89) • [91.. J. droplet (89] " . aerosol (917 . Contact [70 ) • [73,79, 101], drople t Rhin ovlrus Picomaviridae [73, 78°,79•, 1171, aerosol (76, 118] c (82 ) c.d, Contact [35.36.42 ]. aerosol [37 ,40 , 119). Adenovirus Ad8novlrf<1ae Contact [100] Influenza virus Orthomyxovirldae Droplet/aerosol [90,91"18 , 0 [100, 1011 droplet (103 1, aerosol (102 , 103 1 . [55,56,sr,59 ] Taxonom y was based on [621 airtlorne t ransmission is see mingly linked to: WIP [108], ' Blue Book ' (109), 'Red Book ' [110). CDC [3]and Up-To-D ate [111]. The conclusions reflect me conclusions from the auttlOrs . b Contact aerosol Contact aeroso l Contact Contact aerosol Contact Contact [3,110) , droplet [3 ,109-111 ], (3, 109-111 ). (3,109-111 ], droplet [3,109-111 ), (3,109). [3,110 .111). droplet [3,110 , 111]. [3,109-111 ), droplet [3,109 ,110], (109, 111]. (3,110.11 i), droplet [3,110,111]. (111]. drop let [3,111] Contact aerosol Contact aerosol Contact aerosol Contact aerosol [3,110,111 ), dropl et [3, 110, 111), (3 ,110, 111). [109-111 ], droplet [109,1 11). (109-111 ]. (3,109-111 ), droplet (3,109 ,11 OJ, (110, 111]. (109-111 ], droplet [3, 109-111 ), (3, 109-111 ). a b c on experimental data as presented in this table Supersp reade r events. Ona nosooomial situation). • Conclusions w ere drawn based on stability expe riments. d Aerosol-genera 6ng proced ure s Disclaimer: Any third -part y mMerial in thi s email has been shared under fair use provisions of U .S. cop y right law , without furth er verifi cation of its accura cy/ve raci ty_ It do es not necessarily repre se nt my views nor tho se ofNTAJD , NIT-I, HHS , or th e U.S. government. NIH-001442 From: Date: To: Cc: Subject: Fauci, Anthony {NIH/NIAID) [E] Mon, 24 Feb 2020 17:21:34 +0000 Van Hoof, Johan [JRDBE];Erbelding , Emily (NIH/NIAID) [E) Stoffels, Paul [JJCUS) RE: as26 based COVID-19 vaccine candidate Joha n : Thanks for t he note . I enjoye d and learne d fro m yo ur pr esentat ion thi s morn ing. The best way to keep in t ouch w it h NIAID wo uld be t hrou gh Emily and Barney. Best regards,. Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Van Hoof, Johan [JRDBE] Date: Monday, February 24, 2020 11:58 AM To: Erbelding, Emily (NIH/NIAID) [E),-------- Cc: Fauci, Anthony (N IH/NIAID) [E] Subject: as26 based COVID-19 vaccine candidate --------- (b)(6) (b =)~(= > -------- (b)(6) Stoffels, Paul [JJCUS) (b)(6) Dear Emily, Dear Dr. Fauci, First of all, I want to thank NIAID and its team for spending time with us going through the Janssen plans for Ad 26 COVID-19 vaccine development. In follow up of our call earl ier today, please find herewith the key action points I noted from our discussion. I would welcome your perspectives/comments, NIAID. Looking forward to your feedback, NIH-001443 as well as the best way to keep in touch with Best regards, Johan Johan Van Hoof, M.D. Managing Director , Janssen Vaccines and Prevention B.V. Global Therapeutic Area Head IDV, Vaccines, Janssen Pharmaceuticals R&D Phone E- mail Assistant Phone (b)(6) (b) ( Fax : +32 14 60 2841 (b)(6) (b)(6) ************************************************************************************* *********************************** ************************ Follow Up to Ad26 COVID-19 call with NIAID; February 24 th 2020 (b) (4) NIH-001444 (b) (4) NIH-001445 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:53:04 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF ------ - NEJM commentary -- change title? Date: To: Subject: You are correct. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------::-::-=, From: Folkers, Greg (NIH/NIA ID) [El Date: Monday, February 24, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Eisinger, Robert (NIH/NIAID) [E) ________ (b) (6)> (b)( (;)> ~=======~~ Cb _H_, ; Folkers, Greg (NIH/NIAID) [E] (b)(6)> Subject: ASF ------- NEJM commentary -- change title? (b)(5) Disclaim er: Any third -party mat erial in this email has been sha red for intern al use under fair use pr ovisions of U.S. copyri ght law, without furth er verific ation of its accurac y/veracit y. It does not necessaril y re pre sent my views n or th ose of NIAlD, NIH, HHS, or th e U.S. govern ment. NIH-00144 6 Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:51:09 +0000 To: Faye Li Cc: Billet, Courtney (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: RE: Interview Request from China From: Date: Faye : Thank you for yo ur not e. Please send me you r questions by e-mail and I w ill tr y t o answe r th em by e- mail. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Faye Li (b)(6)> Se nt: Monday, February 24, 2020 11:41 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Interview Request from China --------, --------- _...._..,= (b)(6) Dear Dr. Fauci, I'm Faye Li,journalist from the Portrait, a national magazine in China. My beat is science and technology. Since the outbreak of the 2019 novel coronavirus (COVID-19) in China, I'm covering feature stories about the outbreak, hoping to explain to readers what it is, especially since the virus is evolving daily at an unexpected high speed, and in so many confusing ways. Now in China we are getting conflicting information about the new virus and thus become confused about it. For example, we are seeing more and more cases that a patient with negative test results for 2 non-continuous days, still infected with the virus and tested positive afterwards. It makes the treatment really difficult because it seems hard to determine whether the patient is fully cured or not. Since you are an experienced immunologist, I'm wondering if you could share your insights with the Chinese readers and take an interview . The Interview could be via phone or email, whichever works fine for you. NIH-001447 If possible, I'd love to send you the questions before we talk. Since we have time difference, I might not be available dur ing the early afternoon (your time) but I could make it in the morning, noon and maybe late in the afternoon and evening (your time). I'm sorry for bothering you on this subject, but we face severe difficulty in understanding this new virus and taking measures properly. We have quite limited sources and perspectives for understanding this new virus . However, as a science reporter, I believe in a crisis of public health, the informat ion is the key for the public. They should have the opportunity to hear more perspectives from different specialists. Since you are experienced in fighting against so many viruses, especially SARS,I believe your opinions wi ll be inspiring to the readers. It would be of great help and great honor for us to invite you for an interview. A phone call interview would be preferred but if t ime doesn't work for you, is it possible for you to reply via email? I'll list all the questions in deta il. I could be reached by (b)(6) or ______ Best wishes, Faye The Portrait Beijing, China NIH-001448 Cb _)_C6) _, I'm looking forward to your reply. From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 16:01:59 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Call for Dr. Fauci Cristina , please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-=, From: Conrad, Patricia (NIH/NIAID) [El Date: Monday, February 24, 2020 10:46 AM To: Fauci, Anthony (NIH/NIAID) [El Cc: Barasch, Kimberly (NIH/NIAID) [C) (b) ( > (b)(6)> ~---:::======!.,._~~ Haskins, Me linda (NIH/NIAID) [El (b)((;)> ---------- (b)(6) >; Subject: Fwd: Call for Dr. Fauci Is this a friend or do u just want to pass to Cristina. Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Haskins, Melinda (NIH/NIAID) [El" 0 ate: February 24, 2020 at 10:40:37 AM EST To: "Conrad, Patricia (NIH/NIAID) (b) ( [E]" --------=- Cc: "Harr is, Kara (NIH/NIAID) [El" Subject: FW: Call for Dr. Fauci --------- From: Harris, Kara (NIH/NIA ID) [El Date: Monday, February 24, 2020 10:39 AM -------NIH-001449 (bc)( = > (b)(6)> (b)(6)> > To: Barasch, Kimberly (NI H/N IAI D) [ C] Cb)(6J> Cc: Correa, Meylin (NIH/NIA ID) [C] (b)(6J>; Forde, Michae l (NIH/N IAID) [C] (b)(6J>; McCullough, Claire (NIH/NIAID) [E] (b)(6J>; Haskins, Melinda (NIH/N IAID) [E] (b)(6) Subject: RE; Call for Dr. Fauci --------. ---------- a""S"'"7= Hi, KimI spoke to Dr. Jacobs directly . He said that Dr. Michael Lockshin is a good frie nd/fellow Cornell graduate (Dr. Jacobs also noted he went to Cornell) and gave him Dr. Fauci's number. Dr. Jacobs and Dr. Alexander Tarakhovsky, a virologist at The Rockefe ller Institute, would like to speak to Dr. Fauci about the coronavirus. They have a theory that there may be yeast invo lved because it is sticky and perhaps it came from the Chinese government. They want to share their ideas and perhaps start a U.S. government effort "similar to The Manhattan Project." They do not want funding. I thanked Dr. Jacobs for sharing his ideas and stated that I would pass along the message. Should Dr. Fauci wish to speak to them, Dr. Jacobs can be reached at the number below and Dr. Tarakhovsky can be reached at (b)(6) Please let me know if you have any question s. Thanks, Kara From: McCullough, Claire (NIH/NIAID) [E] (b)(6) Date: Monday, February 24, 2020 10:07 AM To: Barasch, Kimber ly (NIH/NIAID) [C] CbH6J> Cc: Harr is, Kara (NIH/NIAID) [E] (b)(6J>; Correa, Meylin (NIH/NIAID) [C] (b)(6)>; Forde, Michae l (NIH/NIAID) [C] (b)(6)> Subject: Call for Dr. Fauci --------~~ --------- Hi, Kim--I got some additional information from Dr. Michael Jacobs office. He is a dermatologist in New York City and said that Dr. Fauci is expecting his call. The secretary provided no further information. Dr. Michael Jacobs (b)( Thank you. Claire A. McCullough Legislative Affairs and Correspondence Management Branc h Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Hea lth 5601 Fishers Lane, Rm. 6F27 - MSC 9806 Bethesda, MD 20892 Tel : (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy NIH-001450 and Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID. NIH-001451 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 15:14:10 +0000 Billet, Courtney (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine 20-02387 Fauci-20-02387-Text.docx, Embargo-Guidelines-5.13.pdf, Production-and- proof.pdf fyi Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FAX: (30 I) 496-4409 E-mail: (b)(6) The i11formation in this e-mail and any of its attachments is confiden tial and may contai n sensitive info1111ation. It should not be used by anyone who is not the original intended recipie nt. If you have r eceive d this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage de vices . The National Institu te of Allergy and Infec tious Diseases (NlAlD) sha ll not accept liability for any statements made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representa1ives. -----Orig ina l Message----From: New England Journal of Medicine Date: Monday,Febrnary 24, 2020 10:00 AM To: Fau ci, Anthony (NlH/NIAID) [E] _____ ...,Cb)( >; Lane, Cliff(NlH/NIAlD) (b)(6) ; Redfield , Robert R. (CDC / OD) (b)(6) Subj ect: New England Journal of Medicine 20-02387 ------ "="'~ [E] -------Dear Dr. Fauci, Tha nk you for the aiiicle , "COVTD- 19: Nav igat ing the U nchartered," which the .Journal is plea sed to accept for pub) ication. Th is accept ance is made w ith the unde rstand ing that neither the artic le itself nor any part of its essentia l sub stance, tables or figures has been pub lished or will be s ubrni t1ed for publication elsew here before it appears in the J ournal. The accepta nce is also made with the understanding that all the auth ors, the data, and its pres entation meet the requirements as desc,ibed in the Recomme nda tions for the Conduct, Reporting , Edi ting and Publication of Scholarly Work in Medica l Journals (www .icm je.org). Please note that the acceptanc e of your comme ntary should be considered confide ntial infonnation to be shared only with your coauthors until its fina l publication. To ensure that no news repo rts about the article appear prematurely in any fonn, do not speak to the media, hold press conferences, or issue news re leases about your paper before the week of publication . You must receive an explicit commitment to w ithhold release of the information until the em bargo is lifted at 5:00 p.m. (Eastern T ime in lhe United States) on the day before. the date of publication. If there are any questions about this policy, you shou ld discus s them with the Editor. We assume that financial relationships creating possible conflicts of interest for all authors have been fully disclo sed to the Editor , including (but not limited to) any relevant rela tionships listed in the Open Payments database at NIH-001452 https://openpaymentsdata.cms. gov/sea rch/phys icians/by-name-and -location for physicians practicing in the United States. For information on what would qualify as a 'relevant' disclosure, please review tbe instructions on page l of your disclosure form. Authors are rem inded that all material published in the Journal is copyrig hted by the Massach usetts Medical Society, that by agreeing to have their manuscript published in the Journa l they !:,>rant to the Society full right and authority to sec ure copyright for the full tenn and any renewals or extensio ns thereof, and that pennission for reprinting must be obta ined in writing from the Journal. The Journal will edit your manuscript in accordance with its estab lished sty le. You will receive a proof of the ed ited manusc1ipt by e-mail; the proof stage will be your next opportunity to make changes . For important info1mation about production and proofs , see the attached document. In the meantime, please do not make any changes or send any new material to us. Tbank you for your contribut ion to the Journal. Sincerely yours, Eric J. Rubin, MD , PhD Editor-in-Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://W\vw.ne jm.org NIH-001453 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 14:22:21 +0000 To: Cc: Subjec t: (b)(6) Barasch, Kimberly (NIH/NIAID) [Cl;Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 Quarantine Ming: Thank you for your note and offer to help. I will ask my Staff Ass istant, Kim Barasc h, co set up a brief call for you to relate your impressions to me. Best regards , Tony Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bu ildin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institutes of Health Bethe sda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have 1·eceived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----- ~m 00~ Date: Sunday , February 23, 2020 7:52 PM To: (NlWNlAID) [El ..._ _____ Cc: Fauci, Anthony (b)(6) -------=-:-:-= CbH __. > Subject: COVID-19 Qua rantine Dear Dr. Fauci , My name is M ing Lei, a Division Director at the NIGMS . I am writing to you as a private citizen , to thank you for your leade rship in yet anoth er public health eme rgency, and to make myself ava ilable to you if you have the time for my in-person observations oftbe COVID-19 caused quarantine in Hub ei Province, China ; the evacuation of Amc1icans; and the quarantine in the US. (b)(6) As the virus sti ll roams around , and a possibili ty of caus ing a pandemic , I want to let you know that I am willing to share with you my direct observations in case such information is of value in the developing of our responses going forward, which you will undoubtedly playing a critical role. l will send you a reminder through my NIH email account, in case this message is put into the junk mail folder. Sincerely , NIH-001454 NIH-001455 From: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 14:03:36 +0000 Billet, Courtney (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Folkers, Greg (NIH/NIAID) [El;Conrad , Patri cia (NIH/NIAID) [El;Routh, Jennifer Date: To: Cc: (NIH/NIAID) [El Subject: Potential Patients RE: FORYOUR REVIEW:Draft Rollout, A ll Staff, and Statement on Preparing for w/ COVID-19 Loo ks fin e t o me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El Date: Monday, February 24, 2020 8:54 AM To: Fauci, Anthony (NIH/NIAID) [El -------= = i>; Marston, (b)( Hilary (NIH/N IAID) [El (b)( >; Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [E) ________ Cb _H_6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Subject: FW: FORYOUR REVIEW: Draft Roilout, All Staff, and Statement on Preparing for Potential Pat ients w/ COVID-19 Renate is asking that I confirm that Dr. Collins' changes (tracked in attachments) sync with what we 've been saying. They look ok to me . What say you? From: Coll ins, Francis (NIH/OD) [El (b)(6)> Date: Monday, February 24, 2020 6:45:07 AM To: Myles, Renate (NIH/OD) [El (b)(6); (NIH/CC/OD) [E] (b)(6); Fauci, Anthony (NIH/NIAID) [E] Tabak, Lawrence (NIH/OD ) [E] CbH6)> NIH-001456 (b)( >; Gilman, James Cc: Burklow, John (NIH/OD) [El CbH6)>;Hallett, Adrienne (NIH/OD) [El (b)(6)1 >; Allen-Gi fford, Patrice (NIH/OD) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] (b)(6); Davey, Richard (NIH/NIAID) [E] (b)( >; Palmore, Tara (NIH/CC/OD) [E] CbH >; Cohen, Justin (NIH/CC/OD) [E] (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Hi all, N icely done, Renate. I made a few edits in two of the documents, see attached. (b)(5) FC From: Myles, Renate (NIH/OD) [E] (b)( Se nt: Sunday, Februa ry 23, 2020 8:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------ =(b= H=6) Collins, Francis (N IH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [E] (b)(6)>; Hallett , Adrienne {NIH/OD) [E] (b)(6)>; Allen-Gi fford, Patrice (NIH/OD) [El (b)( >; Billet, Courtney {NIH/NIAID) [E] (b)(6); Davey, Richard {NI H/N IA ID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) (E] (b)(6)>; Cohen, Justin (NIH/CC/OD) [El (b)(6)> Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 (b) (5) Thanks, all. (b) (5) Latest rollout, all staff and statement are attached . Best, Renate From: Fauci, Anthony (NIH/N IAID) [E] ______ Date: Sunday, Februa ry 23, 2020 8 :15 PM To: Myles, Renate (NIH/OD) [E] _ )_C6) Cb _> Cb)( >; Collins, Francis (NIH/OD) [E] (b)(6JTabak, Lawrence (NIH/OD) [El (NIH/CC/OD) [El --.-.~-== Cc: Burklow, John (NIH/OD) [E] (b =)=(6) ~>--~ (b)(6)>; Gilman , James = (b)( >; Hallett, Adrienne (NIH/OD) [E] NIH-001457 Allen -Gifford, Patrice (NIH/OD) [E] (b)(6) Billet , (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6l; Palmore, Tara (NIH/CC/OD) [E] (b)(6); Cohen, Justin (b)(6) 1>; Courtney (NIH/NIAID) [E) (NIH/CC/OD) [E) (b)(6) > Subject: RE; FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Renate: The rollout plan looks fine except that I would include -------------- (b) (5) Thanks , Tony From: Myles, Renate (NIH/OD) [E] Date: Sunday, February 23, 2020 7:23 PM To: Collins , Francis (NIH/OD) [E]_____ (b)(6)> _.,.(b..._. )= (6); Tabak, Lawrence (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) ~ (bc--c )( =6)> [E] (b)(6)>; Gilman, James ":":' ( N--IH --/-:-:C-:C/-:-:0-:D:--: ) [~E]:-===..;__- Cc: Burklow, John (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) (b)(6)>; Allen-Gi fford, Patr ice (NIH/OD) Courtney (NIH/NIAID ) [E) [E) [E) (b)(6) ; Billet, (b)(6); Davey, Richard (NIH/NIAID) [E] (b)(6)>; Palmore, Tara (NIH/CC/OD) [E) (b)( Cohen, Justin (NIH/CC/OD) [E] (b)(6) Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High Good evening : At tached for your review are draft materia ls to communicate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD), including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potenti al Qs and will work with CCand NIAID folks to develop responses, but I wanted to get t hese products into review in the interest of time. Best, Renate Renate Myles, MBA DeputyDirectorfor Public Affairs Office of Communications and Public Liaison National Institutes of Health NIH-001458 Tel: ----- (b)(6) NIH-001459 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 24 Feb 2020 12:59:47 +0000 Leggio, Lorenzo (NIH/NIDA) [E] RE: Question from the Italian Embassy in DC re: coronavirus Lorenzo Thanks for the note. Unfortunately , I cannot be of any help to you since I myself have no access to this equipment. The best person to contact would be Dr . Robert Kadlec of ASPR at HHS. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail r (b) (6Y The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Leggio, Lorenzo (NIH/NIDA) [E] Date: Monday, February 24, 2020 5:55 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: (b)(6) (b)(6) ---------- ------~~ (b)( > Subject: Question from t he Italian Embassy in DC re: coronavirus Dear Dr . Fauci, I apologize in advance if I write yo u directly to ask this question. I know you are super busy but I thought you cou ld provide some guidance on someone I could contact about this matter. (b) (5) NIH-001460 (b) (5) I know this seems a very technical quest ion and I appre ciate you have many other things on your plate, so I hope you don't mind if I decided to reach you out. I do know that Filippo and his team will be very grateful for any gu idance that they could receive . Thanks in advanceLoren zo Lorenzo Leggio, M.D., Ph.D. Senior Investigator (Clinical), NIDA IRP and NIAAA DICBR Chief, Section on Clinical Psychoneuroendocrino logy and Neuropsychopharmacology , NIDA IRP and NMA DICBR Associate Director for Clinical Research, M edication Development Program, NIDA IRP Senior Medical Advisor to the Director, NIAAA Nationa l Institutes of Health 10 Center Drive {l0CRC/15330) Room 1-5429 Bethesda, MD 20892-1108 251 Bayview Blvd, Room 01A844 Baltimore, MD 21224 Office Phone: Cell: (b)(6) E-mail: --------- (b)(6) (Bethesda); ____ (b)_ C_ 6) (Baltimore) (b)(6) Confidentiality Notice: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and dest roy all copies of the original message. NIH-001461 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 12:42:02 +0000 STEWARTSIMONSON ____ (b_H_ (NIH/CC/BEP) [E] RE: Our story today Thanks, Stewart. We will do it again after Cliff returns from China and fin ishes his 14 day self-quarantine Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------~~ From: STEWARTSIMONSON Date: Monday, February 24, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E_______ (b) (6) > (b>_ <_ > Subject: Re: Our story today Thank you-he is grateful for your help, Tony. He is in a unwindable situation but he is doing what is right and with integrity . (b)( . As do I (b)(6). I really appreciate it. s On Feb 24, 2020, at 7:23 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- Stewart: Here is another article in which I strongly support Tedros. Tony NIH-001462 (b)(6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: John Lauerman (BLOOMBERG/ NEWSROOM:) Date: Mo nday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID ) [E) CbH6J > Subje ct: Our story today --------=-<'"-=-> Hi Dr . Fauci: here ' s o u r story you h ave n 't se en i t. on Te d ros to d ay , in case h ttps:/ / www. b lo omberg . c o m/n ews/fea tu res / 2 0 2 0 - 0 223/ c or o n av iru s - ne ws - who - d ire ct or - g ener a l - r ac e s - a g a in st ti me Th a n ks aga in get a c h ance Re gards , J L for a ll y our help wi t h t hi s o ne . Hop e we t o ta l k aga in soo n . John Lauerman , Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 251028 cell htt p://www . bIoom berg .com http://www .bloomberg .com/prognosis --------- NIH-001463 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon , 24 Feb 2020 12:24:0 1 +0000 John Lauerman RE: Our story today Thanks, John. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: John Lauerma n (BLOOMBERG/ NEWSROOM:) Date: Monday, February 24, 2020 7:04 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) -------=-:-:= Subject: Our story today Hi Dr . Fa u ci : h ere ' s o u r sto r y on Te dr os to d ay , in h a v en ' t s ee n it . https : // www. bloombe r g . com/news/features/2020 n e ws - who - d ir ector - g e n era l - races - against Th a n ks a g a in fo r a ll c h ance to ta l k a g a in Re gards , JL y o u r h e lp soon . with - 02 - 23/co r onavi r us - time thi s on e . Hop e we g e t a John Lauerman, Bloomberg News 3 Queen Victoria Street , London, UK tel. +44 (0) 2035 25 1028 cell ---------=-c-c-='I ______ Cb _>_<6) http://www .bloo mberg .com http://www .bloomberg .com /prog nosis NIH-001464 cas e yo u From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 25 Feb 2020 11:07:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [E] Subject: FW: ACT Additional reading material and developments Attachments: About ACT.Global and its Premium Purity.pdf, ATTOOOOl.htm,ACT CleanCoat February 2020.pdf, ATT00002.htm, ACT ECASystem Februar 2020.pdf, ATT00003.htm, Dr.Brill and Or.Steinmann - ACT CleanCoat Viruzidie englisch EN14476 08.01.2015 Logo Brill.pdf, ATT00004.htm Cristina: Please se if we can engage this person (Richard Tubb) and see what he has to offer. He used to be the White House physician Than ks, Tony From: Fauci, Anthony (NIH/NIAID) [E] Date: Monday, February 24, 2020 10:42 PM To: Biegun, Stephen E (b)( > Cc: Cassetti, Cristina (NIH/NIAID) [El (b)( ; Erbelding, Emily (NIH/NIAID) (El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: FW: ACT Additional reading material and developments --------- Steve: Thanks for the note. I do indeed know Dr. Tubb. He sent me similar material and I am going to connect him with our program people here at NIAIO to see if we can help in any way. Best regards, Tony From: Biegun, Stephen E (b)(6) Date: Monday, February 24, 2020 10:33 PM ------~~ To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Fwd: ACT Additional reading materia l and developments --------- Tony, I expect you know Or. Richard Tubb. He and I worked closely together in the White House 18 years ago. I have a lot of confidence in his judgment, and therefore am forwarding the materials he sent me for your considerat ion. I know nothing about the technologies involved, but I know this is a time to w rite off no good options. Warm regards, NIH-001378 Steve Sent from my iPhone Begin forwarded message: From: Richard Tubb (b)(6)> Date: February 24, 2020 at 8:47:23 PM EST To: "Biegun, Stephen E" (b)( , Robert Kadkec (b)(6) Subject: ACTAdditionalreadingmaterial and developments NIH-001379 (b)(6), From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:22:42 +0000 Marston, Hilary (NIH/NIAID) [E] FW: chloroquine in COVID-19 chloroquine.pdf Let us discuss Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)( Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 > ------~~ -------- (b)(6)> Dear Dr. Fauci, Is there any indication/data to substantiate this claim from China (attached publication) that ch loroquine/hydroxychloroquine can decrease COVID-19 infections and lung disease? Thank you, Philip Gatti, Ph.D. Pharmacologist FDA CDER OND Silver Spring, MD (b)(6) NIH-001430 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 24 Feb 2020 20:21:35 +0000 Marston, Hilary (N IH/NIAID) [E] FW: chloroquine in COVID-19 Chloroquine and SARS.pdf Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confiden tial and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 3:05 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: chloroquine in COVID-19 -------~= --------- (b)(6) Tony , Thanks fo r the quick response . There are data from 2005 showing inhibition of SARS infection and sp read from 2005 . Please see atta ched . Regards , Phil From: Fauci, Anthony (NIH/N IAID) [E) CbH > Se nt: Monday, February 24, 2020 3:00 PM To: Gatti, Philip (b)( > Cc: Lane, Henry C (NIH) (b)(6)>; Cassetti, Cristina G (NIH) Erbelding, Emily J (NIH) (b)(6)> Subj ect : RE: chloroquine in COVID-19 Phil: NIH-001431 ---------- CbH6J ; There are no data in this brief report and so I have no way of evaluating their claim. There are a lot of these types of claims going around. I would love to see their data. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb) (6) FAX: (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gatti, Philip (b)(6) Date: Monday, February 24, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: chloroquine in COVID-19 -------:,,:,--== -------- (b)(6) Dear Dr . Fauci, Is there any indication/data to substantiate this claim from China (attached publicat ion) t hat ch loroquine/hydroxychloroquine can decre ase COVID-19 infections and lung disease? Thank you , Philip Gatt i, Ph.D. Pharmaco logist FDA CDER ONO Silver Spring , MD (b)( 6) NIH-001432 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Wed, 26 Feb 2020 19:07:38 +0000 Tabak, Lawrence (NIH/OD) [E) RE: URGENT- Need your input (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tabak, Lawrence (NIH/OD) [E] (b)(6) Date: Wednesday, February 26, 2020 2:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ; Hallett, Adrienne (NIH/OD) [E] ________ Cb> _C_6); Conrad, Patricia (NIH/NIAID) [El (b)( > ------ -== Subject: Re: URGENT-Need your input Yes- that was the main thing- but any other issues that you can think of in our space? Thanks Get Out loo k for iOS From: Fauci, Anthony (NIH/N IAID) [El (b)(6) Date: Wednesday, February 26, 2020 2:04:38 PM To: Tabak, Lawrence (NIH/OD) (E] CbH6J>; Hallett , Adrienne (NIH/OD) (El (b)(6) 1>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: URGENT-Need your input --------- (b) (5) NIH-001304 Anthony S. Fauci, MD Director National Insti t ute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its represent atives . Fro m : Tabak, Lawrence (NIH/OD) [El Date: Wednesday, February 26, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( > Cb)(6)>; Hallett, Adrienne (NIH/OD) [El ---------- (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: Fwd: URGENT- Need your input I will join call- anything you want brought up? Larry Get Out loo k for iOS From: Pollard, Ashton (05/10S) (b)( > Date: Wednesday, February 26, 2020 1:44:56 PM To: Mango, Paul (HHS/10S) CbH6)>; Lenihan, Keagan (FDA/OC) Cb)( >; Tabak, Lawrence (NIH/OD) [E] Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (OS/ASPR/10) Zeb Iey, Kyle (HHS/0S/OGA) (b)(6)>; Charrow , Robert (HHS/OGC) (b)(6) ; -------- McGowan, (b) (6). Subject: RE: URGENT- Need your input Hi All , I am about to send this invite. Please confirm your attendance via email or by accepting the calendar invite. Thank you, Ashton -----Original Message----From: Mango , Paul (HHS/IOS) Cb)(6) Date: Wednesday, February 26, 2020 I :43 PM To: Lenihan, Keagan (FDA/OC) (b)(6) ; Tabak , Lawrence (NIH/OD) [E] (b)(6) ; McGowan, Robert (Kyle ) (CDC/ OD/OCS) CbH > ; Shuy, Bryan --------- ~= --------- NIH-001305 (OS/ASPR/10) Cb><; Zebley , Kyle (HHS/OS/OGA) (b)( > Charrow, Rober t (HHS/OGC) (b)(6) Cc: Pollard, Ashton (OS/IOS) Subject: URGENT- Need your input Team- Urgen t, how prio rity request: ' --------------------- (b)( (b) (5) Ashton will invite you to a 230pm call to discuss. Plea se organize your responses into bullet points to di scuss with the group. Sent from my iPhone NIH-001306 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 26 Feb 2020 18:25:04 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:Sec. Azar press briefing remarks Att achment s: 2 26 20 press briefing remarks - with Fauci edits .docx Here are my edit s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, February 26, 2020 1:12 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIA ID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( >; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Routh, Jennifer -:--.-----:-:---:--:;:::::::==-...:....--_;,~ (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( > Subject: ASF:Sec. Azar press briefing remarks -------- ------ -:-::~ These are SecAzar's remarks for press tonight . (Plan still evolving.) They are asking for our comments back by 2:45 pm. New content is highlighted to make it easier on reviewers . We're sending your talk ing points down there momentarily. From: Brennan, Patrick (05/ASPA) Date: Wednesday, February 26, 2020 1:07 PM ----------------~~ To: Conrad, Patricia (NIH/NIA ID) [E)~':":"":":"'.:-:-::-:-:=== (b)(6) (b =)=(6) ::.. >..; ; S"'"'. B= onds, Miche lle E. (CDC/00/0ADC) CbH6J>; Galatas, Kate (CDC/0D/OADC) CbH >; Billet, Courtney (NIH/NIAID) [E] =====--!_ Cb)(6):>;Michael, Gretchen (OS/ASPR/OEA) Cb)(6):>; Janik, Heather (FDA/OC) CbH6J>; Caliguiri, Laura (FDA/OC) NIH-001307 (b)(6J>; Lepore, Loretta (CDC/00/0CS) (b)( (HHS/OGC) (b)(6J>; Arbes, Sarah (HHS/ASL) (b)( >; Morse, Sara (HHS/ASL) (b)(6J>; Pence, Laura (HHS/ASL) (b)(6)>; Moughalian, Jen (HHS/ASFR) (b)(6); Shuy, Cait rin (HHS/ASFR} (b)(6); Trueman, Laura (HHS/I EA) (b)(6J v >; Mango, Paul (HHS/105) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)>; Kane, EIieen (OS/ASPR/OEA) (b)((;) ; Shuy, Caitrin (HHS/ASFR) (b)(6)>; Zebley, Kyle (HHS/OS/OGA) (b)(6) Grigsby, Garrett (HHS/OS/OGA) (b)(6J (b)(6)>; Cc: ASPA-Deput ies (b)(6)>; Foster, Timothy (OS/ASPA) McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)> Subject: For review by 2:45 PM: Sec. Azar press briefing remarks ":"."":".-:-:-:;-:-:-:-:-:;:::======-~~ ,..:..!:====="==~- Hi all , Attached is a draft of the Secretary's remarks for this evening 's potential press briefing. Some of this is ro te/ repeated from yesterday or this morning's testimony; I have put the new content in yellow to accelerate review. Please let me know if you have edit s to th is by 2:45 PM . Thank you ! Best, Patrick NIH-001308 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 26 Feb 2020 15:18:25 +0000 Billet, Courtney (NIH/NIAID) [E] RE: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed I do not have time for thi s. Sorry. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, February 25, 2020 10:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> -------=-=-~ (b)(6l>; Marston, Hilary (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad , Patricia (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [E] (b)(6lf>;Stover, Kathy "':'--.-----:-:---:-:::::===~-__:~~ (NIH/NIAID) [E) (b)(6) Subject: Fwd: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed This is an oped for Peter Navarro . We are asked for comments by 10am Weds. (Complicating things a little, he was apparently just on with Tucker Carlson stating parts of it verbat im . So, hopefully th is is accura te!) (b)(6)> From: "Brennan, Patr ick (OS/ASPA)" Date: Tuesday, February 25, 2020 at 8:27:03 PM To: "Conrad, Patricia (NIH/N IAID) [E]" (b)(6)>, "Bonds, Michelle E. (CDC/0D/OADC)" (b)(6)>, "Galatas, Kate (CDC/0D/OADC)" (b)(6)> , "Billet, Courtney (NIH/NIAID) [E]" (b)(6)>, "Michae l, Gretchen (OS/ASPR/OEA)" (b)(6) , "Janik, --------=c--,=, _H_e_ at_h_er_ (:_ F_ D.A..: /_O_C.:.. )'.'..!: =~~------- Cb> _<_6)>, "Caliguiri, Laura (FDA/OC)" CbH6J>,"Lepore, Loretta (CDC/00/0CS) " "':'-~::-:-::-::-::.======:...:...-~= (HHS/OGC)" --------- (b)(6), "Arbes, Sarah (HHS/ASL)" NIH-001325 CbH6J,"Stimson, Brian Cb)( >, " Morse, Sara (HHS/ASL)" (b)(6J>, "Pence, Laura {HHS/ASL)" (b)(6)>, "Moughalian, (b)(6)>, Jen {HHS/ASFR)" (b)(6)>, "Shuy, Caitrin {HHS/ASFR)" "Trueman, Laura {HHS/IEA)" (b)(6) v >, "Mango, Paul {HHS/10S)" (b)(6), "Johnston, Darcie {HHS/IEA)" (b)(6), "Kane, EIieen (OS/ASPR/OEA)" (b)(6)>, "Shuy, Caitrin (HHS/ASFR)" (b)(6)>, "Zebley, Kyle {HHS/0S/OGA)" (b)(6)>, " Grigsby, Garrett (HHS/0S/OGA)" (b)( .""".":"~=====~ = Cc: "ASPA-Deputies" , "Foster, Timothy (OS/ASPA)" ---------- (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)"------=- (b"""' )(= 6) Subject: For review by 10:00 AM Weds: Peter Navarro coronavirus op-ed Hi all , Attached is a draft op-ed from the WH's Peter Navarro regarding the administration's coronavirus response - covering PPE,vaccines, therapeutics, and diagnostics. There is a lot going on here so we'd like to have edit s/ recomm endati ons/ affirmativ e clea rance from FDA, CDC, NIAID, ASFR, and ASPR. Please send edits to me and Tim Foster by 10:00 AM tomorrow {Wednesday}. Thank you! Best, Patrick NIH-001326 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 26 Feb 2020 02 :19:38 +0000 Tabak, Lawrence (N IH/OD) [E) RE: LHHSappropriators coronavirus supplemental brief 3:30p Wednesday Date: To: Subject: Than.ks, Lany ! -----Original Message ----From: Tabak , Lawrence (NIH/OD) [E] (b) (6) Date: Tuesday, February 25 , 2020 9:0 l PM To: Fauci , Anthony (NIH/NIAID) [E] (b)( > Subject: FW : LHHS appropriators coronav irus supp lemental brief3:30p Wednesday -----~~= Tony, l will be able to do this . hopefully we can move this back in the correct direction. La rry On 2/25/20, 9:00 PM, "Cochran , Norris (HHS/ASFR)" Correc tion, Norris ---- ------------ (b)( wrote: (b) (5). Thank you in advance. > On Feb 25, 2020, at 8:55 PM, Cochran, Non -is (HHS/ASFR) > > Dr. Tabak , Neil - would you be available to brie --------- (b)(6) > wrote: (b)(5) (b) (5) We would ha ve CDC on the line as well. ASPR by phone or in person. We will be in person. Please let me know either way. Thank you in advance. > > Norr is NIH-001343 From: Date: To: Fauci, Anthony (NIH/NIAIO) [El Tue, 25 Feb 2020 03:46:47 +0000 Davey, Richard (NIH/NIAID) [El;Palmore, Tara (NIH/CC/OD) [E] (b)( ;Conrad, Patricia (NIH/NIAID) [El FW: 4 Add itional COVID-19 Asymptomatic Positive Indiv iduals Identified at ------- Cc: Subject: Travis AFB Rick/Tara: Please give me a call -----=~-::;---:---:-----:-:----:-:my office at (b)(6) If in the evening/night home phone is (b)(6). (b)(5Ji. If during business hours, please call call my cell phone at (b)(6). My Thanks, Tony ----------------=-c-= -------- (b)(6)> From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 24, 2020 10:40 PM To: Kadlec, Robert (OS/ASPR/10) (b)( >; Stecker, Judy (OS/10S) (b)( 6)> Cc: Harrison, Brian (HHS/10S) (b)(6); Fauci, Anthony {NIH/N IAID) [El (b)(6)>; Palmore, Tara (NIH/CC/OD) [El CbH6l>;Yeskey, Kevin (OS/ASPR/10) (b)(6); Greene, Jonathan (OS/ASPR/EMMO) ________ Cb _>_C6);Lee, Scott (OS/ASPR/EMMO) (b)(6)> Subject: Re: 4 Additional COVI0-19 Asymptomatic Positive Individuals Identified at Travis AFB thanks From: "Kad lec, Robert (OS/ASPR/ 10)" --------- (b)(6)> Dat e: Monday, Feb rua ry 24, 2020 at 10 :37 PM To: " Tabak, Lawrence (N IH/OD) [E)" (b)(6)> ---------:a = CbH6J>,"Stecker, Judy (OS/10S) " --------- Cc: "Harrison, Brian (HHS/10S)" (b)(6) Anthony Fauci CbH6)"Palmore, Tara (N IH/CC/OD) (E]" ---------Kevin (OS/ASPR/10)" , "Greene, Jonathan CbH6)>,"Yeskey, (OS/ASPR/E M MO)" Cb)( ·>, "Lee, Scott (OS/ASPR/EMMO)" (b)(6) Subject: RE: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB ---------Larry would be ------------------- From: Tabak, Lawrence (NIH/OD) [El --------- (b)(5J. (b)( Best Bob > Se nt : Monday, February 24, 2020 10:28 PM To: Kadlec, Robert (OS/ASPR/IO)_______ Cb _H_6)>; Stecker, Judy (OS/10S) (b)(6)> Cc: Harrison, Brian (HHS/10S) CbH6);Fauci, Anthony (NIH/N IAID) [El (b)(6) Palmore, Tara (NIH/CC/OD) [El CbH6J; Yeskey, Kevin ------~~ ---------- NIH-001380 (OS/ASPR/I0) ~..;.__..;._...;....!==~ (b:;:: )( 5"'">-; CbH6)> ; Greene , Jonathan (OS/ASPR/EMMO) L :-e-e-, S :--cott ( OS/ ASPR/EM MO ) Cb)(6)> Subject: Re: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB - Any idea on t iming? - please let me know --------------------- (b)(S ) Thanks Larry (b)(6) From: "Kad lec, Robe rt (OS/ASPR/ 10)" Date: Monday, February 24, 2020 at 10:26 PM To: "Stecker, Judy (OS/ 10S)" Cc: "Harrison, CbH6)> Brian (HHS/10S)" CbH6)>, Tara (N IH/CC/OD) [E]" --------- CbH6)>, CbH6)> , Anthony Fauci (b)(6) "Pa lmore, "Yeskey, Kevin (OS/ASPR/ 10)" "Greene, Jonathan (OS/ASPR/EMMO)" "Lee, Scott (OS/ASPR/EMMO)" Subject: FW: 4 Additional CbH6)>, " Tabak, Lawrence (NI H/OD) [E]" --------~~ CbH6)>, CbH6)1 COVID- 19 Asymptomatic Posit ive Individuals Identified at T ravis AFB (b) (5) From: Kadlec, Robert (OS/ASPR/I0 ) Se nt: Monday, February 24, 2020 10:19 PM To: Harrison, Brian (HHS/I0S) (b)(6)>; Stecker, Judy (OS/10S) (b)(6)> ; Mango, Paul (HHS/10S) (b)( >; Murphy, Ryan {OS/ASPA) =======~~ "'.""'"'---:'"'"""".'""".'.""'.-:".'.".:-:=== (b): (:6)::.. ;_ A_ r b_e...; s,~S=arah (HHS/ASL) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) (b)(6)>; Tabak, Lawrence (NIH/OD) (E] (b)(6)>; Redfield , Robert R. (CDC/OD) (b)(6); McGowan , Robert (Kyle) (CDC/OD/OCS) (b)(6)>; Trueman, Laura (HHS/I EA) (b)( ; Mougha lian, Jen (HHS/ ASFR) (b)(6)>; Johnston, Darcie (HHS/IEA) (b)(6)> Cc: Lee, Scott {05/ASPR/EMMO) (b)(6)>; Yeskey, Kevin (OS/ASPR/I0) (b)(6) 1>; Waters, Cicely (OS/ASPR/OEA) (b)(6)>; Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Greene, Jonathan {OS/ASPR/EMMO ) CbH >; Imbria le, Samuel (OS/ASPR/SIIM) (b)(6)>; Austin, Meredith (uscg.m il) (b)(6) 1>; Herrmann, Jack {HHS/ASPR/OPP) (b)(6) Ferro, Phil J. EOP/NSC CbH6)>; Ruggiero, Anthony J. EOP/NSC CbH6)>; Cavanaugh, Brian J. EOP/NSC (b)(6)> Subject: 4 Additional COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Importance : High --------- -~-~~===t.....:....-~~ ---------= ~ ========~-:;;---:--:-------:----:-:':-" ---------- Th is evening, we were advised by the State of California that 4 passengers from the Diamond Princess tested positive by the CDCfor COVID-19. NIH-00138 1 One ind ividua l who tested positive by the CDChad been tested positive in Japan and is already in hospital in CA. We are developing the following possible Courses of Act ion as the State of CA cannot absorb these 3 addit ional asymptomatic ind ividua ls: ..__ ________________________ NIH-001382 ""~'"'(""' (b S) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 18:46:26 +0000 Moughalian, Jen (HHS/ASFR) RE:Close Hold Review - Send comments by 1:40 pm Jen : I had cha nge d th e Thanks, Tony (b) (5) --------------- Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31 , Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b) (6>r> From: Moughalian, Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:43 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; McGowan, Robert (Kyle) (CDC/0D/OCS) (b) (6)>; Shuy, Bryan (os·~ ; A"."". S ~P-:: R-:'. / 1-:: 0':": ) ====~(b "")'""' (-=" ; Kadlec, Robert (OS/ASPR/10) (b)(6) •> ; Grigsby, Garrett {HHS/0S/OGA) (b)(6); Zebley, Kyle ~---::---:--'"""'":'-==-~ (HHS/0S/OGA) (b)(6) Lenihan, Keagan (FDA/OC) (b)(6)>; Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cochran, Norris (HHS/ASFR) (b)(6)>; Cabezas, Miriam (HHS/ASFR) (b)( >; Hittle, Taylor (HHS/ASFR) (b)(6) Subject: RE:Close Hold Review - Send comments by 1:40 pm ------~~ --------- Thanks for the quick response! From: Fauci, Anthony {NIH/N IAID) [El (b) ( > Se nt: Monday, February 24, 2020 1:42 PM To: Moughalian, Jen {HHS/ASFR) (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Shuy, Bryan (O ~S :-: / :--:A:-: SP :-:R:-: / :-: 10:-:)=====-~ (b"'" ) "C-="I ( >; KadIec, Robert (05/ ASPR/10) (b)( >; Grigsby, Garrett {HHS/0S/OGA) (b)(6) Zebley, Kyle ":"""."~:-:-:-:-:-":""'."'':'-::===~..:.........:::__;:;.,..,= (HHS/OS/OGA)______ Cb _>_C6); Lenihan, Keagan {FDA/OC) CbH6)>; ---------=-:--:= NIH-001439 Redfield, Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris (HHS/ASFR) (b)(6)> ; Cabezas, Miriam (HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: RE: Close Hold Review - Send comments by 1:40 pm --------Jen: See my sugges ted edits in red. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Moughalian , Jen (HHS/ASFR) Date: Monday, February 24, 2020 1:18 PM To: McGowan , Robert (Kyle) (CDC/O0/OCS) (b)( >; Kadlec, Robert (OS/ASPR/1O) (b)(6) (b)(6)>; Shuy, Bryan (OS/ASPR/IO) (b)(6) Grigsby, Garrett ------- (b) ( >; Fauci, (b=)(:6)~>;_Z=ebley, Kyle (HHS/OS/OGA) (b)(6)>; Lenihan, Keagan (FDA/OC) >; Redfield , Robert R. (CDC/OD) (b)(6) Cc: Cochran, Norris {HHS/ASFR) (b)(6); Cabezas, Miriam {HHS/ASFR) (b)(6)>; Hittle, Taylor (HHS/ASFR) (b)(6)> Subject: Close Hold Review - Send comments by 1:40 pm (HHS/OS/OGA)_~~==== Anthony (NIH/NIAID) [E) ------------------- Importance: High Close hold . Please see below draft 0MB language for a possible emergency supplemental request. Due to the fast moving nature of this process, please send comments by 1:40 PM. Numbers are still under discussion, and we will share more info in the daily update. NIH-001440 (b) (5) Jen Moughalian Assistant Secretary for Financial Resources (ASFR) US Department of Health and Human Services ----- (b)(6) (Office) ----- (b)(6) (Cell) NIH-001441 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 02:00:10 +0000 To: Myles, Renate {NIH/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 ----------------------From: Myles , Renate (NIH/OD) [E] Date: Sunday, Februa ry 23, 2020 8:56 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(5) Thanks. (b)(6) (b)(6)>; Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Gilman, James {NIH/CC/OD) [El (b)(6)1 Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne {NIH/OD) [El (b)(6)>; Allen-Gifford, Patrice {NIH/OD) [El (b)( >; Billet, Courtney (NIH/NIAID) [E) (b)( ; Davey, Richard {NIH/NIAID) [El (b)( >; Palmore, Tara (N IH/CC/OD) [El (b)(6)>; Cohen, Justin ":'" { N- IH - /':"':' C-:C/':"':' 0-:0 -:-:: ) [~E]:-=~ (b)(6) > Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Latest rollout, all staff and statement are attached. Best, Renate From: Fauci, Anthony {NIH/NIAID) [E] Date: Sunday, February 23, 2020 8:15 PM To: Myles, Renate (NIH/OD) [E] ; Collins, Francis (NIH/OD) [E] ; Tabak, Lawrence {NIH/OD) [E) ; Gilman, James (NIH/CC/OD) [El Cc: Burklow, John (NIH/OD) [E) ; Hallett , Adrienne (NIH/OD) [E) ; Allen-Gifford, Patr ice (NIH/OD) [El ; Billet, Courtney (NIH/NIAID) [E) ; Davey, Richard {NIH/NIAID) [E] ; Palmore, Tara (N IH/CC/OD) (E] ; Cohen, Justin {NIH/CC/OD) [El Subject: RE: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potent ial Patients w/ COVID-19 Renate : The rollout plan looks fine except that I would include Thanks, NIH-001603 (b)(6) Tony From: Myles, Renate (NIH/OD) [E] (b)(6)> Date: Sunday, February 23, 2020 7:23 PM To: Collins, Francis (NIH/OD) [E] (b)(6); Tabak, Lawrence (NIH/OD) [E] CbH6)>; Fauci, Anthony (NIH/NIAID) [El CbH6)>; Gilman, James (NIH/CC/OD) [El CbH6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Hallett, Adrienne (NIH/OD) [El (b)(6) 1>; Allen-Gi fford, Patri ce (NIH/OD) [El (b)(6); Billet, Courtney (NIH/NIAID) [E) (b)(6); Davey, Richard (NIH/NIAID) [El (b)(6); Palmore, Tara (NIH/ CC/OD) [E] (b)(6J>; Cohen, Justin {NIH/CC/OD) [E] (b)(6)> Subject: FORYOUR REVIEW: Draft Rollout, All Staff, and Statement on Preparing for Potential Patients w/ COVID-19 Importance: High ------~~ ----:-~---:-:===!.-..:.... _ ___:_~ ~ Good evening: Atta ched for your review are draft materia ls to commun icate NI H's preparation for potential receipt of patients with COVID-19 to the NIH Clinical Center (timing TBD),including: 1. Rollout plan 2. All staff emai l 3. Statement These materials were reviewed by Rick Davey, Tara Palmor e, and Courtney Billet. I am developing a list of potential Qs and will work with CCand NIAID folks to develop responses, but I wanted to get these products into review in the interest of time. Best, Renate Renate Myles, MBA Deputy Directorfor Public Affairs Office of Communicationsand Public Liaison NationalInstitutesof Health Tel: (b) (6) NIH-001604 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:14:18 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Important regarding CoronaVir us To: Subject: Please handle. ---------------- From: Date: Sunday, February 23, 2020 6:10 PM To: Fauci, Anthony {NIH/NIAID) [E] (b) (6) > ------~~ (b)( 6) -------- (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Subject: Important regarding CoronaVirus Respected Dr. Anthony It was great to know about you and your institution, for efforts in combating any emerging infectious disease. I am writing this email regarding our preliminary observation about the coronav irus genome . I wish to share with you we have foun d 12 mirro r DNA sequence wit hin the genome of Coronavirus . We have named it (MRl to MR12) . we are highly interested in MR2 as this mirror DNA sequence is absent in the human genome. (b)(4) I wish to add here t here are few studies which state t hat mirror DNA has the potentiality to fo rm H-DNA and later has a potent iality to induce mutations. We strongly believe a future study on mirror DNA can answer " Why some virus mutates faster? " "Can we stop them from mutating? (b)(4) (b) (4) I will be than kful to you, If you can give me your valuable t ime to discuss telephonically or through skype our ideas. I can be reached at (b)( . I look forward to hearing from you. with regards and Best wishes Dr Vikash Bhardwaj (PhD JNU India) Asst Professor Biotechnology Starex University Gurugram India. NIH-001605 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [El Sun, 23 Feb 2020 23:11:59 +0000 Lerner, Andrea (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El RE: COVID-19 clinical care team l am totally aware of all of this and have been directly involved in sening it up. You have my OK to partic ipa te to the extent that you desire. -----Original Mcssage----From: Lerner, Andrea (NTH/NJAJD)[E] _______ Date: Sunday, February 23, 2020 5:39 PM To: Fauci , Anthony (NIH/NIAlD) [E) _____ Subject: COVID-19 clinical care team (b _ )_ (_6) > _, (b ""' )""' (= > Dear Dr. Fauci , l got a call a few minute s ago from Veronique Nussenblatt , Chie f of the Clinica l Center ID Consult Service, regarding me being a part of the clinical care team of COVID-19 patients if they come to the NIH. She did not have any definitive infonnation but said there was a chance patients could be coming from California this week - this is the first J had heard of that, and l'm guessing you may know more about it than 1 do. The work would include either day or night shifts, likely a couple a week. People on the clinical care team are not instrncted to separate themselves from others and will be per tested for the virus daily when working clinically. l wanted to ask for your OK to do this clinical work - of course I will maintain my responsibilities in the office while doing so. Please let me know and happy to discuss further if you'd like. Sincere ly, Andrea Sent from my iPhone NIH-001606 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 21:35:02 +0000 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Crawford, Chase (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: Flip Cards I have gone over the Flip cards. I note that we have only 2 cards fo r Coronavirus. I want to have a separate flip fo lder for coronavirus with a ful l set of cards for the specific coronavirus hearings that are coming up. You should sit down with me and also work with Hilary to prepare this set of cards. They should contain all the current epi as well as the dollar numbers for the proposed supplemental budget that we are putting together- I will get asked about that and I have clearance from the department to talk about it. Also, I want a set of cards for what we are doing in the area of research, i.e. basic research (eg animal models, etc.), diagnostics, therapeutics (remdesivir trials in China, Japan, and Nebraska), and the whole menu of vaccines. In other words, I want an entire set of cards for coronavirus. That is what I am going to get asked in both the coronavirus hearings as well as in the NIH Appropriations hearing s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not ac cept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . NIH-001607 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 21:22:40 +0000 Jon LaPook RE:Coronavirus reality check How about a pastrami sandwich on rye and a potato knish? Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,,;:;-----~ (b~)~(6) = Date: Sunday , February 23, 2020 4:16 PM To: Fauci , Anthon y (NlH/NlAID) [E] Subject: Re: Coronav irus reality check ------~~ (b)( · Thanks , Tony. 1 would love you to cons ider my request to "tag along " with you some day - not to join you for meeti ngs (I would wait outside unless invited in) or listen in on conference calls but to chat with you in between to give people an inside look at how serio usly the gove rnm ent is taking the outbreak. And Tcould bring down a shmear from Barn ey Greengrass for lunch. How could you pass that up??? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS News Professor of Medicin e NYU Langone Health Tw itter @ DrLaPook On Feb 23, 2020, at 4:05 PM, Fauci, Anthony (NIH/NIAID) [E] .__ _____ Cb _H__> wrote: Jon : The current appearance of community transmissions in Japan , South Korea , Italy and Iran is troublesome . As I have repeatedly said over the past couple of weeks , if and when (looks more like when now) a numbe r of other countries besides China have sustained human to human transmissions , then we will be on the briJJk of a pandemic, NIH-001608 if not already there. The reason to say this is that when several countries have widespread transmissions, then spillover to other countries is inevitable since one cannot shut out the rest of the world and so you can expect increasing world-wide transmissions among progressively more countries. In esse nce , you will be expe1iencing a pandemic. We are not quite there yet, but we are getting disturb ingly close. It will soon be a matter of se mantic s regarding who would be willing to call it since it is not a mathematically precbe definition. I am not so sure that WHO will have the will to declare this a "pandemic" before a number ofrespected epide mi ologists around the world start rcfciTing publicly to it as a pandemic regardle ss of what WHO docs or does not declare. WHO will likely be behind the curve here and wi ll wait until it is patently obviou s what we are dealing with. Hope that this is helpful. Best, Tony Anthony S. Fauci, MD Director National lnstitute of Allergy and Infectious Diseases Building 31 , Room 7 A-03 31 Center Drive , MSC 2520 National lostitutes of Health Bethe sda , MD 20892-2520 Phone: ------ (b)(6) FAX: (301) 496-4409 E-mail: -------- (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive i11fom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook ,.:::;...----. (b ~)~(6) = Date: Sunday , February 23, 2020 3:47 PM To: Fauci , Anthony (NIH/NIAJD) [E] Subject: Coronavims reality check --------,;;..,....,. (b)( = Hi Tony, Why do I not think that this is a relaxing S1mday for you? NIH-001609 This definitely feels like an inflection point in the coronavirus outbreak - both in the unsurprising way it's spreading and the equally unsurprising misinfom1ation and public alann/panic we are seeing. Unsurprising but here we are. Can you give me a quick brain dump on where you think we are and how r can best inform the pub lic? Thanks, Jon P.S. please let me know whenever I can report that the outbreak is officially being called a pandemic. Jonathan LaPook , M.D. Chief Medical Correspondent , CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-001610 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 23 Feb 2020 20:01:51 +0000 Richard Allen Johnson RE: 2020.02.23 Sunday Dick: Transmission is definitely by respiratory droplet. Still unclear about aerosol transmission although there are anecdotal reports that this occurs similar to what we saw in individual episodes with SARSback in 2002-2003. Almost certainly contact transmission occurs with hand to mucosa (mouth, eyes, nasal mucosa). Unclear about fomites, doorknobs, etc. Virus can live for a couple of hours on certain inanimate objects. Virus definite ly isolated from stool and urine, but not sure of role in transmission. No information about Transm ission to fetus. Children have very low rate of infection . No good serologic test at this point although they are rapidly being developed . Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Richard Allen Johnson --------- Date: Sunday, February 23, 2020 2:32 PM To: Fauci, Anthony (NIH/NIAID) [E]-------.. (b)( > Subject: Re: 2020 .02.23 Sunday CbH > (b... )= (6>l>;Richard Allen Johnson Thanks, Tony. Please continue communication with me by email. But rest your voice for a short whlle. I am having tro uble understanding the exact mode of transmission of COVID-19. NIH-001611 -Sneeze or cough produces respiratory droplet or aerosolized respiratory secretion which make contract with upper or lower respiratory mucosa, which results in infection of human cells. Seems most likely. - What about contact transmission, contaminated hand to conjunctivae, nasal mucosa, or mouth - Fecal/oral - transmission to fetus -What are the diagnostic tests to confirm diagnosis of novel coronavirus? PCRof secretions? Who in the world has these test kit; who manufactures kit. -Are follow up serologies begin done? Interest ing questions to us and to Shelly Wolf if he were with us. Thanks, Tony. My voice is also a little raspy. Best, Dick On Sun, Feb 23, 2020 at 10:46 AM Fauci, Anthony (NIH/NIAID) [El -------- (b)(6) wrote: Dick: My voice is hoarse since I have been giving so many Congressional and White House briefings and TV and radio interviews. I just need to shut up for a while . Best, Tony From: Richard Allen Johnson ----------Date: Sunday, February 23, 2020 5:25 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ ______ (b)( Cb) _C6) _ > Subject: 2020 .02.23 Sunday Hi, Tony I continue to follow the Cobid-19 epidemic . What is the problem with your voice. It crackles like mine. I attribute mine to 'postnasal drip.' WHO and Dr. Tedros are looking much better on TV. He has the WHO logo in the background . His tie show be tighter . His slouch is better . He still puts his elbows on the table in front of him. Looking forward to lunch with you. Best, Dick NIH-0016 12 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 23 Feb 2020 15:56:48 +0000 To: Margolis, Leonid (NIH/NICHD) [E] Cc: Cassetti , Cristina (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Coronavirus tissue test system: a suggestion Thanks , Leonid. I will pass this on to appropriate associates. Best regards, Tony -------------~~ -------- From: Margolis, Leon id (NIH/N ICHD) [E] (b)(6)> Date: Sunday, Februa ry 23, 2020 5:50 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Coronavirus tissue test system: a suggestion Importance: High Dear Tony, As you may know, for many years we study HIV pathogenesis in human tissues ex vivo. (Among my many papers, there is one, may be not the best, but that I am most proud of. This is where my co-author is Dr. Fauci ©) (b)(5) Regards, Leonid Leonid Margolis, Ph .D. Head, Section of lnte rcellular Interactions Eunice Kennedy -Shriver National Institute of Child Health and Human Development Building 29B, Room 1H16D 29 Lincoln Drive Bethesda, MD 20892 Phone: (b)(6) Fax: 301-480-0857 (b)(6) e-mail: --------- NIH-001613 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:53:48 +0000 john won RE: KAMA John: Thank you very much for your kind note . I hope that all is well with you. Best regards, Tony From: john won (b) (6) > Date: Sunday, February 23, 2020 9:06 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: KAMA ------------- ..-.-,= (b)(6)> Dear Dr. Fauci, I hope you are doing well . Your participation during our Washington DC 20 17 convent ion was one of the most memorable events of our organization's history. United Stat es and t he world now turns to you for your help as Coronavirus crisis is becoming pandemic. All of us here at KAMA are thinking about you and all those affected . Thank you very much for all your contributions. Warm regards, John Won On Oct 24, 2017, at 10:42 AM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- John: Thank you for your kind note. It was a pleasure to be with you. Best regards, Tony From: john won (b)(6) Date: Tuesday, October 24, 20 17 10:12 AM To: Fauci, Anthony (NIH/NIAID) [E) _____ __..,_ (b_.. )(=6)> Subje ct: KAMA NIH-0016 14 (b)(6) Dear Dr. Fauci, Thank you very much for speaking to us at the 43rd Annual KAMAConvention . It was a tremendous privilege for all of us. You were also so kind to stay afterwards to take pictures with all those who asked. To be honest, having you there was very surreal. You symbolize the best of American medicine. I grew up idolizing your accomplishments as college and medical student. You saved and touched the lives of so many around the world . It is still hard to believe that I had this special opportunity to welcome you. We will continue to do our best to serve the pub lic and mentor medical studen t s. I hope you can speak to us again in the near future . Thank you very much. I hope you continue in your position for another 40 years. Warmest regards, John H. Won NIH-001615 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 23 Feb 2020 15:52:06 +0000 Julia Belluz RE: Comment? Julia: The appearance of community transmissions in Japan, South Korea, Italy and Iran is troublesome. As I have repeatedly said over the past coup le of weeks, if and when (looks more like when now) a number of other countries besides China have sustained human to human transm issions, then we are on the brink of a pandemic, if not already there. The reason to say th is is that when several countries have widespread transmission, then spill-over to other countries is inev itable since one cannot shut out the rest of the world and so you can expect increasing world-wide t ran smissions . Hence, you will be experiencing a pandemic. We are not quite there yet, but we are getting disturbingly close. I hope that this is helpful. Best, Tony From: Julia Belluz Date: Sunday, February 23, 2020 4:13 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6J> Cc: julia.belluz@voxmedia.com; Conrad, Patricia {NIH/NIAID) [E] Kimber Iy {NIH/NIAID) [CJ (b)(6) Subject: Comment? ------ -=~ --------- (b)(6J>; Barasch, Dear Dr. Fauci, Just over a week ago we talked for th is story about how the outbreak is likely larger than we know now : https://www .goog le .com/amp/s/www .vox.com/p latform/amp/2020/2/ 14/2113 4473/coronavirus outbreak -singapore-us-symptoms-pandemic Given the developments in Singapore, Iran, Italy, and on the Diamond Princess cruise ship, I'm just wondering how your opinion about the possibility of conta inment and how fast we are approaching a pandemic has changed. Do these developments suggest we've entered a new phase in the outbreak? If you have a few minutes to chat or email today, let me know. We'll be aiming to run a story on this today. Thank you for considering. Julia NIH-001616 On Feb 15, 2020, at 12:10 AM, Julia Belluz wrote: Thank you so much for making the t ime to comment at w hat I know is a crushingly busy time . As usual don't hesitate to ping if you have any further comments or questions ! Julia https :ljwww .vox.com/2020/2/14/21134473/coronav symptoms-pandemic irus-outbreak -singapore-us- Sent from my iPhone On Feb 14, 2020, at 1:21 PM, Fauci, Anthon y (NIH/NIAID) [E] (b)(6) wrote: --------- Julia: I just called you now {7:20 AM Washington , DC time) and got mvoice mail in German that I could not understand. You can call me at CbH Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representativ es. NIH-001617 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID)[E) Sun,23 Feb2020 14:26:22+0000 Theodore Li RE:Covid-19question Ted: Thanks for the note. Since she is 22 days out of Singapore she would be well beyond the 14 day quarantine used for people who are coming out of risk zones. And so although her risk is never zero, it is really very low . If she were coming from Japan or South Korea, which are experiencing an emerging outbreak, I might feel a litt le different, but Singapore has good infection control despite the number of cases in that country Given her history of recent Shingrix vaccination, I would wait another day to see if her fever breaks. I agree that I would keep her at home for now. I do not think it would come to that, but if you want to get testing done , it still would have to go to the CDCvia the Virginia department of health . Bottom line is that I wou ld sit tight fo r now and see how she does over the next day or so. If things change, do not hesitate to call or e-mail me. Best, Tony From: Theodore Li Date: Sunday,February23, 2020 9:11 AM To: Fauci,Anthony (NIH/NIAID)[E)-----Subjec t : Covid-19 question (b)(6)> --=(b"""" )(=6) Hi Tony, The wife of one of my patients received the Shingrix vaccine on Thursday 2/20 and developed fever to 101.4 the following day with malaise, headache, mild nausea (no respiratory symptoms). She's taken ibuprofen with transient temperature reduction; the fever and symptoms are the same today. BUT ... she and her daughter were in Singapore (b)(6)where they stayed at the ;....~========---=-=-:-= (b)(6), visited (b)(6) and the (b)(6). They then flew to Colombo, Sri Lanka before returning via Europe last (b)(6)to (b)(6). So her fever began 3 weeks plus 1 day after being in Singapore. I've to ld her to keep treating the fever and symptoms but to stay at home for now. The fever after Shingrix usually resolves after 2-3 days so I'd expect it to abate today or tomorrow. My question is whether there's enough of a concern, viz. the time in Singapore, for her to be tested for covid-19 . If so, what's the best way to conduct the testing? Or is it okay to see if her fever breaks by tomorrow? (You must be getting lots of these questions). Best, Ted ------ NIH-0016 18 From: Date: To: Cc: Fauci,Anthony (NIH/NIAIO)[E) Sun, 23 Feb 2020 04:27:10 +0000 Tabak, Lawrence (NIH/OD) [El Colli ns, Francis {NIH/OD) [El -------=-:-=,;Conrad, Patricia (NIH/NIAID) ------- [El Subject: (b)(6) Heads Up Larry : I need to speak with you tomorrow (Sunday) about a request that we (NIH) will get from ASPR(Kadlec) regarding the housing of asymptomatic coronavirus positive individuals. I am copy ing Francis since the discussion will ultimately get to him. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001619 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:06:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: OB Roberts Cb)~ > Date: Saturday, February 22, 2020 4:03 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus ------~~ -------- Cb)( > To: Dr. Fauci FM: Oliver B Roberts (b)(6) Dr. Fauci; I attended a small water seminar, put on by local (Seventh Day Adventist) medical professionals, in the mid 1970's at Elms Haven, California . This seminar taught the participants how to eliminate the flu with the use of water treatments, ie (steam baths, etc). I have now for these past 40 some-odd years, been taking two treatment 's; one in the evening and another in the middle of the night, whenever I have contacted the flu: AND have had the facilities to do so; and each time I was well the next morning. No temperature, no symptoms whatsoever. With the high rate that this Coronavirus is spreading, one can see what a great tool these treatments can be for medical professionals. To have those who are sick with the flu, complete ly free of all symptoms after two treatments would greatly ease the burden on Dr's and other medical professiona ls AND each facility. NIH-001627 Dr. I am asking for a few minutes of your time to explain this. I would like to share this with you and others. I just want to help by sharing what I learned and have been doing all these years. I feel so guilty, knowing this and not having a way to get this information to those needing it, when there so many out there sick and dying. Note: I have been trying to reach out, hoping someone wi ll hear me. Alas I do not have the education, pedigree nor the contacts: But you Dr. have all three! I ask not that you believe in me, but that you believe in these treatments. Thank You for your time, please feel free to contact me via email or by phone or text or even have someone up here talk with me. Sincerely; OB Roberts {Ben) NIH-001628 Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 21:04:58 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) Subject: FW: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help? - The New York Times From: Date: Please set up a call w ith Hannah Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------, .....,....,= (b)(6) From: Valant ine, Hannah (NIH/OD) [El Se nt: Tuesday, February 18, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Congratulations and time to speak: Researchers Are Racing to Make a Coronavirus Vaccine. Will It Help?- The New York Times Import ance: High --------- Hi Tony, I have been following this terrific work by NIAID scientists in the VRC- congratulations! htt ps://www .nyt imes.com/2 020/ 01/28/he alth/c oronavirus-vaccin e.htm l As you can imagine I am delighted see Dr. Kizzmekia Corbett playing a leading role in these activities . Most importantly she is de lighted with the mentorship, sponsorship and opportunity she has received at NIH, particularly from Barney Graham. (b)(6), (b)(S) Please let me know when you might be availab le to speak with me . Best, Hannah NIH-001629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 20:53:35 +0000 NIAIDODAM FW: CUGH Annual Meeting Let bus discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Thomas Quinn (b)(6) Date: Thursday, February 20, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-=--== (b)((;)> Cc: Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad , Patricia (NIH/NIAID) [E] (b)(6J>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6)>; Judith Wasserhei t Cb)<> Subject: CUGHAnnual Meeting -----:-~::======-~= Hi Tony, I know how busy you are but I wanted to give you a brief update on the Annual Conference of the Consortium of Universities fo r Global Health (CUGH) based in Washington, DC. Here is the link to the overall CUGH meeting which provides an overview of the whole conference https ://www .cugh2020 .org/program . As we discussed months ago you agreed to be in the opening day plenary session on April 18th , entitled "Emerging Infectious Diseases and their Impact on Global Health Security". The details and other speakersare listed below. I may try to organize a call of all speakers in a month to coordinate talks/topics as the session is 90 minutes with 5 speakers, and a lot of ground to cover, especially with the COVID19 outbreak. NIH-001630 Judy Wasserheit, copied here, would also like to invite you to a special session she is organizing on the coronavirus epidemic at the same CUGH conference in a latebreaker session on Sunday, April 19 (the second day of the conference) from 8:4Sam-10:1Sam at the Washington Hilton Hotel (Monroe Room). This talk would be slightly different from the plenary session and you could expand on COVID19 research prior ities and update on progress. We realize your schedule is very busy but your insights and knowledge on both of these topic s is unparalleled. If you cannot speak at the second session we would appreciate your recommendation as to an alternative who could address this latter topic. Thanks and all the best, Tom Plenary Session Details: Session Day: Saturday, April 18, 2020 Session Time : 11:30am-1:00pm Location: Washington Hilton Hotel, International Ballroom Panel Title: "Emerging Infectious Diseases and their Impact on Global Health Security" Short Panel Description: This Plenary Panel will highlight the continual threats of emerging and re-emerging infectiou s diseases, and their impact on global security for surveillance, detection, treatment and prevention of these diseases. Over recent decades, multiple epidemic events have underscored how highly vulnerable we are to viral threat s. Our world is globally connected-and an "emerging threat" in one part of the world can pose a threat everywhere and to everyone. About 75 percent of new human diseases are caused by microbes that originate in animals. These include HIV, influenza (including pandemic HlNl, HSNl , and H7N9), Severe Acute Respiratory Syndrome (SARS),Middle East Respiratory Syndrome-Coronavirus (MERS-CoV),Ebola, Marburg, and Nipah. The recent emergence of COVID from China clearly illustrates the magnitude , rapidity NIH-001631 and impact that a new infectious agent can have on global health security. This panel of leading experts will discuss the emergence of these microbial threats, and our ability to detect, respond and prevent future epidemics of these pathogens . Moderator(s) Info: Tom Quinn, Chief, NIAID, International HIV/STD Section and Man Charurat, Director, Division of Epidemiology and Prevention, Institute of Human Virology (IHV) Speaker(s) Info: 1. Anthony Fauci, Director, NIAID 2. Chikwe lhekweazu, Director General, Nigeria CDC 3. Peter Hotez, Dean, National School of Tropical Medicine, Baylor College of Medicine 4. Jonna Mazet, Executive Director, One Health Institute, and Pl, PREDICTproject, UC Davis 5. Jennifer Nuzzo, Senior Scholar, Center for Health Security, Johns Hopkins University NIH-001632 From: Date: To: Cc: (NIH/NIAID) [El Subject: Attachments : edits.docx Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:51:00 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg RE: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial NIAID press release COVID-19 treatment trial FOG- with fauci tracked See my minor tracked edits. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 3:55 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIA ID) [El (b)_C_ >; Folkers, Greg (NIH/NIAID) [El (b)(6)> Subject: FORASF REVIEW:Draft PR re: launch of remdesivir COVID-19 trial _______ Hi Dr. Fauci, Please find attached for your review a draft press release to announce the launch of the remdesivir COVID-19 treatment trial, which enrolled its first patient today. It's been reviewed by the following • • • • • • individuals/groups: FOG OCGR(Kathy Stover, Courtney Billet) DMID: Emily Erbelding, John Beige! OCR: Cliff Lane, Libby Higgs U Nebraska {Ch ristop her Kratochvil, Andre Kalil, comms dept) Awaiting comments from Gilead and WHO. NIH-001633 For ease of reference, the following is the quote we have drafted for your use: (b) (5) Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402- 1663 NIH-001634 To: Cc: Fauci,Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 20:38:12 +0000 Conrad, Patricia (NIH/NIAID) [El Routh, Jennifer {NIH/NIAID) [El Subject: RE: interview request: draft responses for Greek newspaper From: Date: Good j ob! See my minor edits in red. Thanks. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 4:57 PM ----------------~~ [El --------- (b)( To: Fauci, Anthony (NIH/NIAID) (b)(6) Subject: FW: interview request: draft responses for Greek newspaper Do you want to edit these ..greek paper/pring? Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nation al Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: Th e information in this e- mail and any of its attachments is confidential and may contain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it NIH-001635 from your mailbox or any other storage devices . National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Routh, Jenn ifer (NIH/NIAID) [E) CbH6J> Date: Friday, February 21, 2020 4:52 PM To: Conrad, Patricia (NIH/NIA ID) [E) ------~~ (b)(6)>; NIAID FOG Cc: NIAID COGCORE; NIAID Media Inquir ies Subject: int erview request : d raft responses for Greek newspaper Reporter: Theodora Tsoli Organization : Greek newspaper To VIMA (www.tovima .gr) Phone #(s): CbH6),thtsoli@tovima .gr Subject: COVID-19 Deadline: Monday 2/24 The reporter emailed questions for ASF. I have drafted proposed responses for his review , also attached. 1. Do you believe that SARS-COV2 is capable of causing a pandemic? Are you expecting many secondary transmissions of the virus outside China? A pandemic is generally defined as sustained transmission of a new pathogen in multiple regions of the world. COVID-19 does not yet meet that definition , and I hope that China and other countries in Asia with some transmission are able to contain the outbreak. However , it is possible that COVID-19 could become a pandemic. It would not be surprising to see additional secondary transmissions of the virus outside of China. 2. Chinese authorities are reporting a decline of new cases. Could we say that the virus has peaked and maybe it will slow down? When are you expecting to have a clearer picture about the evolution of this epidemic? Although the number of daily cases in China appears to have gone down , it is too early to tell if this is really a decline in the outbreak. 3. Could the virus become endemic and give seasonal outbreaks? If China is not able to contain the outbreak, it is possible COV ID-19 could become endemic and lead to seasonal outbreaks. However, it is too early to know the likelihood of this scenario. 4. What about its transmissibility? Some experts say that WHO is underestimating it's transmissibility. Could the reality be different maybe because, among other things, many cases stay undetected? Because of the many unknowns about SARS-CoV-2 , it is difficult to make any firm conclusions regarding overall transmissibili ty and severity. However , it appears to be much more transmissible than SARS. Also , there are likely asymptomatic COVID-19 infections that are not getting counted because people do not go to the doctor for testing or treatment if they are not sick. NIH-001636 s. Do you believe that the measures taken by China and countries around the world are adequate to stop SARS-COV2 spread? There is a lot of discussion about thermal cameras and travel restrictions for example. China has taken extreme measures to control the outbreak. Restricting the movement of 50 million people is unprecedented. However, it might ultimately have an effect on slowing transmission. Precautions implemented in the U.S. are not intended to detect every person with COVID-19 entering the country. Howev er, our approach has allowed us time to better plan and prepare our health system . 6. What is the key to stop the worldwide spread of the virus? Though we have mobilized a rapid research response to quickly develop effective countermea sures, right now, the outbreak response remains focused on the proven public health practices of identifying cases , isolating patients and tracing contacts. 7. In the northern hemisphere we have a flu outbreak - in Greece as well. Some experts say that this is the real danger and not the coronavirus. What is your view? I am always concerned about influenza . Every flu season , millions of people are at risk of getting very sick or dying. Currently people in the U.S. and most countries in the northern hemisphere are at a much higher risk of being exposed to influenza than SARS-CoV-2. However , the COVID-19 outbreak is an evolving situation and we are treating it as a very serious public health threat. 8. Many efforts are being in process for the development of a vaccine for the new coronavirus . Are you coordinating any of them and which ones? Are there any efforts more promising than others? Which platforms of vaccine development are more promising? When do you believe that we could have a vaccine available for clinical trials and then for human use? NIAID is exp loring multiple candidates and is on track to test an experimental messenger RNA (mRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinical testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recipients. It is important to realize that the development of investigational vaccines and the clinical testing to establish their safety and effectiveness takes time. A vaccine against the novel coronavirus will likely not be widely available for more than a year. 9. What about therapies? Dozens are being tried - from plasma to herbal medicines in China. Which are the most promising? NIAID is pursuing the development of antivirals and monoclonal antibodies for potential use against COVID-19. NIAID is preparing protocols for in vitro and in vivo studies of the antivi ral remdesivir, which has shown promise agains t other coronaviruses in animal models . NIAID also plans to evaluate Kaletra (lopinavir/ritonavir) and interferon-beta for their activity against SARS-CoV-2 . In addition, NIAID scientists are working to identify monoclonal antibodies with NIH-001637 therapeutic potential from stored SARS patient samples as well as COVID-19 patient samples . 10. Are the things we know about this new virus more than the ones we don't know? Which are the main questions about it that remain to be answered? New data are published about SARS-CoV-2 every day. However, we still have a lot to learn. For example, we do not know why there are so few cases among children, which is uncommon for a respiratory virus. 11. How worried should people outside China be about SARS-COV2? What is the biggest danger from this virus? . The risk to the general American public remains low at this time ; however , this could change and that is why we are treating the emergence of a novel coronavirus as a very serious public health threat. We understand that people may be worried . We ask that people not let fear or panic guide their actions. 12. Which are the protective measures anyone should take against the new virus? Do masks work? The vast majori ty of people outside of China do not need to wear a mask. A mask is more appropriate for someone who is infected than for people trying to protect against infection . Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)C Disclaimer : The informatio n in this e-mail and any of its attachments is confidential an d may contain sensitive informati on. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the se nder and d elete it from you r mailbox or any other storage dev ices. The National Institu te of Allerg y and Infectious Diseases shall not accept liab ility for any sta tements made that are sender's own and not express ly made on behalf of the NIAID by one of its rep resentat ives. NIH-001638 From: Date: To: Subj ect : Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:48 +0000 Cassetti, Cristina (NIH/NIAID) [El RE: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Cassett i, Cristina (NIH/NIAID) [El Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Erbelding, Emily (NIH/NIAID) [El CbH > Subject: Fwd: HHS Engages Sanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine ------~~ ~======= ~= ---------- This is the press release from ASPR, in case you need more information on the Sanofi CoV efforts Cristina Begin forwa rded message: --------- (b)(6) From: "Folke rs, Greg (NIH/NIAID) [E]" 0 at e: February 18, 2020 at 3:07 :21 PM EST Subject: HHS Engages Sanofi' s Recombinant Techn ology for 201 9 Nov el Coronav iru s Vaccine FORIMMEDIATERELEASE February 18, 2020 Conta ct: ASPR Press Offic e 202 -205 -8117 aspr m ed ia@hh s.gov NIH-001639 HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR,will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus . The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediately to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks ." BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexib ility to make millions of doses of vaccine quickly in an influenza pandemic. In 2016, BARDA added this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile. When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development , and in December 2019 the partners began focusing on increasing manufactu ring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment, or diagnostic for novel coronavirus infections; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHSand with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in development for Middle East Respiratory Syndrome (MERS) or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect, protect against or treat novel coronavirus infections. To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government NIH-001640 launched a single point-of -entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine. public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats . Within ASPR,BARDA invests in innovation , advanced research and development , acquisition, and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools , and non-pharmaceutical products needed to combat health security threats . To date, 54 BARDA-supported products have achieved regulat ory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scient ific communities, together with government and venture capital investment, to drive innovation that will strengthen our nation's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov. For more information on partnering with BARDAon developing medical countermeasures , visit www .medicalcount ermeasu res.gov, and for more on DRIVe, visit dr ive.hhs.gov . ### Note: All HHS press releases, fact sheets and other news materials are available at https://www .hhs.gov/news . Like HHS on Facebook @, follow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any thfrd-part y material in this ema il has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH, HHS , or the U.S. govern ment. NIH-001641 From: Date: To: Subject: Vaccine Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:41:42 +0000 David Willman FW: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Davi d : See press release below regardin g BARDA and Sanof i. Best, Tony Antho ny S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cassetti , Cristina (NIH/N IAID) (E] ---------Date: Saturday, February 22, 2020 2:26 PM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b '"'~..-. (6) = > ---------- Cc: Erbelding, Emily (NIH/NIA ID) [E) (b)(6) Subject: Fwd: HHS EngagesSanofi's Recombinant Technology for 2019 Novel Coronavirus Vaccine This is the press release from ASPR,in case you need more information on the Sanofi CoV efforts Cristina Begin forwarded message: From: " Folkers, Greg (NIH/NIAID) [E]" (b)(6)> Date: February 18, 2020 at 3:07:21 PM EST Subject: HHS Engages Sanofi's Recombinant Technology for 2019 Nov el Coronav iru s Vaccine NIH-001642 FOR IMMEDIATE RELEASE February 18, 2020 Cont act: ASPR Press Off ice 202-205 -8 117 asprm edi a@hh s.gov HHS EngagesSanofi's Recombinant Technologyfor 2019 Novel Coronavirus Vaccine Racing to develop a vaccine against the 2019 novel coronavirus, the U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response has engaged Sanofi Pasteur, the vaccines global business unit of Sanofi. The Biomedical Advanced Research and Development Author ity (BARDA), a component of ASPR, will provide expertise and reallocated funds to support the vaccine's development . Sanofi will use its egg-free, recombinant DNA platform to produce a recombinant 2019 novel coronavirus vaccine candidate. The technology produces an exact genetic match to proteins of the virus . The protein 's DNA will be combined with DNA from a virus harmless to humans, and used to rapidly produce large quantities of antigen which stimulate the immune system to protect against the virus. The antigens will be separated and collected from these cells and purified to create working stocks of vaccine for advanced development. "Flexibility and scalability are cornerstones of rapid response to an emerging infectious disease," said BARDADirector Rick A. Bright, Ph.D. "Using this proven technology, we can pivot immediate ly to address this new global health threat. Our goal is a licensed vaccine to provide long-term health security against this latest virus and prevent future coronavirus outbreaks. " BARDA has worked with Sanofi since 2004 and in 2009 began collaborating with Protein Sciences of Meridian , Connecticut, now owned by Sanofi, to develop a recombinant technology with the flexibility to make millions of doses of vaccine quickly in an influenza pandemic . In 2016, BARDAadded this vaccine to the U.S. National Pre-pandemic Influenza Vaccine Stockpile . When Sanofi purchased the company and its technology in 2017, BARDA continued working with Sanofi on pandemic vaccine development, and in December 2019 the partners began focusing on increasing manufa ct uring capacity for recombinant influenza vaccine in the United States, in accordance with a president ial execut ive order to enhance national security and the public health by modernizing influenza vaccines and technologies . This expanded collaboration with Sanofi is BARDA'ssecond program to focus on developing a novel coronavirus vaccine candidate in the past few weeks. There is currently no approved vaccine, treatment , or diagnostic for novel coronavirus infect ions; however, the U.S. Food and Drug Administration has issued an emergency use authorization (EUA) to enable emergency use of a diagnostic test developed by the Centers for Disease Control and Prevention. BARDAalso is working with counterparts across the government, including within HHS and with the Department of Defense. The team is reviewing potential vaccines, treatments and diagnostics from across the public and private sectors, particularly products in NIH-001643 development for Middle East Respiratory Syndrome (MERS)or Severe Acute Respiratory Syndrome (SARS),to identify promising candidates for development and licensure to detect , protect against or treat novel coronavirus infections . To obtain information about any potential products in development in the private sector that could be used in responding to the novel coronavirus outbreak, the U.S. government launched a single point-of-entry website for innovators and product developers to submit brief descriptions of their diagnostics, therapeutics, vaccines, and other products or technologies relevant to this new virus. Federal agencies are particularly interested in identifying products and technologies that have progressed into or beyond non-clinical studies, have established large-scale commercial Good Manufacturing Practices (cGMP) manufacturing capability, and/or have utilized a platform already approved by the U.S. Food and Drug Administration (FDA). BARDAalso opened an easy broad agency announcement, an EZ-BAA, specific to diagnostics that utilize platforms already cleared by the FDA, w ith a viable plan to meet requirements for the FDAto consider Emergency Use Authorization (EUA) within 12 weeks of an award. About HHS, ASPR, and BARDA HHS works to enhance and protect the health and well-being of all Americans , providing for effective health and human services and fostering advances in medicine, public health, and social services. The mission of ASPRis to save lives and protect Americans from 21st century health security threats. Within ASPR,BARDA invests in innovation, advanced research and development , acquisition , and manufacturing of medical countermeasures vaccines, drugs, therapeutics, diagnostic tools, and non-pharmaceutical products needed to combat health security threats. To date, 54 BARDA-supported products have achieved regulatory approval, licensure or clearance. BARDA DRIVe brings together the best ideas from the medical and scientific communities, together with government and venture capital investment, to drive innovation that will strengthen our nat ion's health security . To learn more about preparing for and responding to publ ic health emergencies, from new infectious diseases to natural disasters and bioterrorism, by visiting the HHS public health emergency website, www .phe.gov . For more information on partnering with BARDAon developing medical countermeasures, visit www .medicalcountermeasures .gov, and for more on DRIVe, visit drive .hhs.gov . ### Note : All HHS press releases, fact sheets and other news materials are available at https://www.hhs .gov/news . Like HHSon Facebook @, fo llow HHSon Twitter @HHSgov@, and sign up for HHS Email Updates . Last revised: February 18, 2020 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . 1t does not necessarily represent my views nor those of N.lAJD, NIH, HHS, or the U.S. government . NIH-001644 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 19:39:17 +0000 Kevin Thurm RE:Thanks From: Date: To: Subject: Kevin : M any t hanks for yo ur kind note. yo u. Mu ch appreciated. I hope that all is we ll w ith Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kevin Thurm Cb)(6) > Se nt : Saturday, February 22, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [El -------=-c-s-= CbH >; Fauci, Anthony (NIH/NIAID) [El (b) ( > -------- Subject: Thanks Tony Good afternoon. Just wanted to write and say how much I deeply appreciate your on-going public service; you've made extraordinary contributions over the course of your career and, as I've watched you on TV in the context of the current public health threat of the coronavirus , I know you're continuing to do so... No need to respond; you have a lot going on. From one citizen and a former colleague, extending my thanks and deep appreciation. Best wishes. NIH-001645 Kevin Thurm NIH-001646 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 19:36:40 +0000 Folkers, Greg (NIH/NIAID) [E] RE: For review: ASM presentation for 26Feb2020 ASM Public and Scientific Affairs Committee Meeti ng 2nd FINAL for 26Feb2020 .pptx I mistaken ly put it into my Documents. now Here it is, and I will put it into the OD Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Date: Saturday, February 22, 2020 2:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:For review : ASM presentation for 26Feb2020 ------~~ I don't see it in OD -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, February 22, 2020 1:49 PM To: Schneider, Johanna (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ,.;...;;.....:.....====::a: (b)(6)> -------~= (b)(6)> (b~) ;; ~ ;;>-; -= c -on_r_a~ d , Patricia (NIH/NIAID) [E] (b) (6) > Subject: RE: For review : ASM presentation for 26Feb2020 This is now "2 nd FINAL" in the OD folder. You just need to remove the instruction slides and do the required updates on several of the slides and then it is ready to go . Thanks. NIH-001647 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . ---------- From: Schneider, Johanna (NIH/NIAID) [El Se nt : Friday, February 21, 2020 4:05 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6) ------~~ ..:.::=======:~~ >; Conrad, Patricia (NIH/NIAID) [El --------- Subject: For review: ASM presentation for 26Feb2020 Dr. Fauci, Attached is the presentation to the American Society for Microb iology (ASM) Public and Scientific Affairs Committee on Wednesday Feb 26th. The top ics they have expressed interest in are: • NIAID Budget Request FY2021 • Novel Coronavirus • Progress on a Universal Flu Vaccine The talk is 30 minutes plus 15-20 for discussion. I've scheduled 30 minutes Monday morning at 10AM to review the slides with you as well. The presentation has been uploaded to the shared dr ive. As indicated we wil l update the necessary slides on Monday afternoon before sending them to ASM on Tuesday. Thanks, Johanna NIH-001648 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 19:33:57 +0000 Cassetti, Cristina (NIH/NIAID) [E] RE: Question Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------------=-,-:-= From: Cassetti, Cristina (NIH/NIAID) [El (b)(6)> Date: Saturday, February 22, 2020 2:22 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Erbelding , Emily (NIH/NIAID) [E)_______ (b)(6) ~=======~Cb_>_C6>l _. > Subject: Re: Questio n Hi Dr. Fauci, This effort is completely driven by BARDA. DMID is not involved. Crist ina On Feb 22, 2020, at 2:18 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: (b)( > Cristina: What is the relationship that we (DMID/NIAID) has with Sanofi in the development of a coronavirus vaccine? Are we funding them? Do we NIH-001649 have any agreement with them to develop a coronavirus vaccine, or is it BARDA who is dealing w ith them? Thanks, Tony Anthony S. Fauci , MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: Cb)(6) FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001650 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 18:32:37 +0000 Eisinger, Robert (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El Nabel NAS nom ination (b)(6) 2020 NAS Nomination - Section 44 - 02 -22-2020.docx Bob: Here is CbH6)NAS nomination. uploaded to the website. Thanks, Tony Let us touch bases on Monday to get it Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001652 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 14:08: 16 +0000 Marlene Colucci David Rubenstein;Ginni Rometty;Donahoe, John RE: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - To: Cc: Subject: Thank you ! Marlene : Thanks for the note. It was my pleasure, and I never m iss an opportun it y to interact with David. He is an incomparable interviewer. Best, Tony From: Marlene Colucci Date: Friday, February 21, 2020 2:40 PM To: Fauci, Anthony (NIH/NIAID) [E]_____ _____, (b).-.(=6)> __________ (b)( >; Cc: David Rubenstein (b) (6); Ginni Rometty _, (b) (6) > Donaho e, John Subject: Business Council - Dr. Anthony Fauci "fireside chat" with David Rubenstein - Thank you! Dr. Fauci, We wanted to send a quick note to thank you for join ing us today. Your discussion with David was so interesting and we ll received . The coronavirus alone was o n the minds of so many CEOsas it impacts thei r supply chain. David, it goes w ithout saying that you are the best interviewer! enterta ining . Wish ing everyone an enjoyable weekend! Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR NIH-001653 You make everything substanti ve and 'I ~ 1 BUSl ESS (. <. L \,( l L T : 202-298-7650 C: (b)(6) F: 202-785-0296 NIH-00 1654 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 22 Feb 2020 14:06:21 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: CoVid-19 In Infants Please hsandle. -----Original Message ----Fr om: JF K (b) (6) Date: Friday , February 21, 2020 2 :44 PM To: Fauci, Anthony (NIH/NIAID) [E]..._ _____ Subject: CoVid- 19 In Infan ts ------~~ _ )_ <.... (b Dr. Fauc i, Infants and childr en infected with CoVid-19 seem to be an anomaly. Could it be as simp le as childhood vaccinations? Are Chinese childr en vaccinated with anti malarial drugs such as Chloroqu ine phosphate , which is proving effective in older patients for CoVid-19? If infants and childr en are not getting severe infections, why? Jonathan F. King NIH-001655 Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 14:00:30 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov) FW: Session Planning fo r COVID-19 at CROI; Tuesday March 10, at 12:10 PM From: Date: To: Cc: Subject: Eastern Daylight Time fyi From: Kevin Bowen Se nt: Friday, February 21, 2020 6:31 PM To: Donna Jacobsen ; Zunyou Wu {CDC/DDID/NCHHSTP/DHPSE) (NIH/NIAID) [E] Brooks, John T. -'."";:::======~~ Fauci, Anthony (b)(6); (b)(6) '""""":-:-:-.:::=====::.....----------------- (b -...)""' (6) = El-Sadr, Wafaa M . (b)(6)>; Schooley, Robert (b)( ·; Schooley, Chip (b)(6)>; Eron, Joseph J Jr (b)(6)>; Genesis Regalado (b)( >; Barie, Toni C (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: RE: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time ========""'"';'"~;-' ==========!...;..~ ------------ Dear CROI Speakers and Moderators: We would like to schedule a planning call for next week to COVID-19 session at the 2020 Conference on Retroviruses and Oppor t unistic Infections (CROI). Please submit your availability using the poll at http://whenisgood.net/ksy42az . The poll should automatically adjust to your local time zone, but you can adjust the setting using the "Select your location" dropdown if needed. We will confirm the call as soon as possible. Regards, Kevin Bowen Program Director CROI Scientific Program and IAS-USAProduction From: Donna Jacobsen Date: Friday, February 21, 2020 1:37 PM To: Zunyou Wu (b)( >; John T. Brooks MD RaIp h S >; Fauci, Anthony (NIH/NIAID) [El Cc: Sharon Hillier PhD El-Sadr, Wafaa M. ~=======~:;;---(b)( ,> (b)(6)>; Barie, (b)(6) (b)(6)>; Kevin Bowen 'RobertT. Schooley, MD (b)(6)>; Eron, Joseph J J ,. (b)(6)>; Kevin Bowen ; Genesis Regalado ; Barie, Toni C _________ _ ; Schooley, Robert (b)(6) ---------------- NIH-001658 Cb)( >; Conrad, Patricia (NIH/NIAID) [E] CbH6J> -------------Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Import ance: High Dear Drs Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in this special session in on ly about 2 weeks. We are all very grateful , and know t his will be tremendously impactful for the CROIaudience. Below is the final list of present ations , although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afte rnoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly apprec iate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL LUNCHllllESESSIONONCXMJ 19 Tue. 3/ 10: 12:10 PM -1 :20 PM EASTE~ DAYLIGHTTIME Auditorium Preliminary Sess i onAgenda {Order andtalk.titlesto be confirmed) 1, FOCUSON THE EPIDEMIOLOGYOF COVID-19 AND EFFORTSIN CHINA a. zY.Jrt.qy. Wu, ChineseCenter for OiseaseContro~ China 1.5-minute live video (Skyll" or Zoom)updote from Ch'no 2. FOCUS ON THE GLOBAL EPIDEM IO LOGY OF COVI0 - 19 AN D EFFORTSTO CO NTROL TH E OVT6REA,C: a. John Brooks, VS Cente -----~ Cc: Marietta Ethier (NIH/NIAID) [E] ~=> (b)( (6 t Emily Lane ;>; Fauci, Anthony Subject: Re: Triple E letter Tony, my condominiumcommunity has established a program in which prominent members of the Washingtonarea are invited to make presentationson subjects of great public interest. Shown in the email below is a descriptionof this program. In this regard I have been asked to contact you to see, recognizing your incrediblybusy schedule, if you would be interested and able to provide an update on the Coronavirus situation to our residents. Most likely you _____________________ __., Cb ,)......, (6) If you have a potential interest in sharing your great expenise on this subj ect with our residents could you please have your staff contact Emily Lane who is copied on this email to explore possible dates and limes thal would work for you . Thank you so much for your consideration of this request. Ken On 2/2 1/20, 3:36 PM, "Emily Lane" ;Fauci, Anthony (NIH/NIAID) [El Subject: FW: Session Planning for COVID-19 at CROI; Tuesday March 10, at 12:10 PM Eastern Daylight Time Import ance: High Since this is a taping fo r his remark s - can hi lary do thi s call since she is doin g the slides? hate to waste ASFt ime on this with all our other moving part s....ju st a thought. Patricia L. Conrad Public Hea lt h Analyst and Special Assistant to the Director National Institute of Alle rgy and Infectious Diseases Th e Nationa l Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may conta in sensitive info rmatio n. It sh ould not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and de lete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NiAID ) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Friday, February 21, 2020 4:37 PM To: Zunyou Wu (b)( >; Brooks, John T. (CDC/DDID/NCHHSTP/DHPSE) (b)(6)>; Barie, Ralph (b)(6)>; Fauci, A nt hony (NIH/NIA ID) [El (b)( > ~=====~~ Cc: Sharon Hillier PhD --------------------------NIH-001662 (b)(6] . (b)(~ EI-Sadr, Wafaa M. ========-~;5""-:--'.~-:--. (b) (6); Schooley, Robert (b) (6); (b)(6J>; Kevin Bowen Schooley, Chip ";::::=======-~~-=..... _; ; Eron, Joseph J Jr Kevin Bowen ; Genesis Regalado (b) (6)> ; Barie, Toni C _, CbH 6));Conrad, Patricia (NI H/NIAID) [E] (b)(6) Subject: Session Planning for COVID-19 at CROI;Tuesday March 10, at 12 :10 PM Eastern Daylight Time Importance : High ______________ ---------~~ = Dear Ors Wu, Brooks, Barie, and Fauci: It is more than incredibly imp ressive at how all of you, in just the past few days, have rearranged your schedules and agreed to participate in th is special session in only about 2 weeks. We are all very grateful , and know this will be tremendously impactful for the CROIaudience. Below is the final list of presentations, although the order and titles may well change. We are hoping to have a conference call with the session liaisons and speakers next week if possible, to go over each of the talks to address the overall plan and discuss any overlap. Shortly we will send out a poll for availabi lity for early morning in China, early-mid afternoon in the US West Coast, and late afternoonevening in the US East Coast. If you can respond to the poll by Monday we would greatly appreciate it; things are moving quick ly. Many thanks again, All of us at CROI! SPECIAL WNCH111\E SESSION ONCOV[) 19 Tue, 3/10: 12:10 PM - 1:20 PM EASTE~ DAYLIGHT TIME Auditorium Preliminory Sc>:.ionAgendo (Orde1 1md tol k.title, to be con firmed) 1. FOCU~ON TliE EPIDEM IOLOGYOF COVID-19AND EFFORTSIN CHINA a. ?uoxouWu, ChineseCenter for OiseaseContro~China 15-minvte livevideo (Skypeor Z.oom)vpdatefromCh:fl(I 2. FOCUSON fHE GLOBAi.EPIDEMIOLOGY OFCOI/ID-19 AND EFFORTS TO CONTROLTHE OIJT6REA~ a. John Ofo<> k!I, VS Cent~o fo,- Di)C~ C<.mt,d,.USA 15-minute update 3. FOCUSON rHE VIROLOGY OF COROtl OVIWS6 OVERAL~MOLECULAR ASPECT S OF TRANSM ISSION TO HUMANS. PATHOGENES IS IN M ICE MODELStl NOPARALLE lS INIHUMANS,ETC a. Ralph Sar ic. Universityof North carolina, U SA 25-minute lecture 4, FOCUS ON N fA I0/HIH EFFORTS TO STUDY NOVE L CORONOV IRVSESAN O OEVElO P DIAGN OSTICS. TH ERAPEUTICS, ANO VACCINES a. Anthony Fauti, National Institute of AJlergyandInfectiousDiseases,. National InstitutesoJHea!th, USA 15-minute recordedupdate NIH-001663 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 12:06:10 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: DEARTONY: CORONAVIRUS Please handle. ----------------= ~ (b)(6)> From: Dr. Michael Jacobs Date: Friday, February 21, 2020 6:14 PM To: Fauci, Anthony (NIH/NIAID) [E] _..:....:....:.!:=======;= Lockshin, Michael MD (b)(6 )1> Cc: Alexander Tarakhovsky (b)(6); Dr. Michael Jacobs Subject: DEARTONY: CORONAVIRUS -------- (b)(6); ---------- (b)(6) > dear tony: i am a cornell medical school cum~ raduate. i am associate professor of dermato logy at wei llcornell in private practice. (b)(6) aIexand er tarakhovsky is (b)( and a professor at rockefeller university. he is a virologist. -----------------------=-~ ---.---.---:====~~-~-~----~-.---------- we have been fo llowing the corona virus pandemic closely, and a few days ago became alarmed at t he news that the chinese government is sterilizing their paper money from hube i province . we th ink that there is a possibility that the virus was released from a lab in wuhan, the biotech area of china. we also th ink that the vi rus might be complexed with another organism , such as a yeast or fungus, to make it more sticky. we would like to discuss this with you further. we feel that immediate action must be taken by united states scientists to try to neutralize this t hreat . please contact alexander and me at your earliest convenience at above emails or my mobile (b)(6) or office (b)(6) michael lockshin gave me you r email. ----- with kind regards michael jacobs NIH-001664 From: Date: To: Subject: Attachments : Please handle. Fauci,Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 11:49:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Cai & Garen 1995.pdf, Cai & Garen 1996 .pdf, Cai & Garen 1997.pdf Thanks . From: Garen, Alan (b)( > Date: Friday, Feb ruary 21, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Garen, Alan (b)(6)> Subject: coronavirus (b =)""' (6) => Dear D. Fauci, I want to suggest t hat NIAID arrange to collect serum samp les from Coronavirus patients who have survived a major infection and probably have genera te d antiviral antibod ies. My laboratory showed in the attached papers that such antibodies could be cloned from sera using a powerfu l technology called Phage Display. The project cou ld be initiated in this country with as few as 2 patients. Sincerely, Afan Garen, Yale Univers ity NIH-001665 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 11:39:57 +0000 Antoniak, Cynthia (NBCUniversal, MSNBC) Goldner, Shannah (NBCUniversal);Conrad, Patricia (NIH/NIAID) [E] RE: MSNBC Reconfirming No problem . Seeyou then. From: Antoniak, Cynthia {NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 6:39 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: MSNBC Reconfirming If you could get there by 7:3Oam ...that would be great! From: Fauci, Anthony (NIH/NIAID) [El (b)( > Date: Saturday, February 22, 2020 6:38 AM To: Antoniak, Cynthia (NBCUniversal, MSNBC) Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: [EXTERNAL)RE: MSNBC Reconfirming I have received this e-mail and confirm 7 :45 AM hit . What time do you want me at the studio? From: Antoniak, Cynt hia (NBCUniversal, MSNBC) Date: Saturday, February 22, 2020 5:49 AM ------~= To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Goldner, Shannah (NBCUniversal) ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: MSNBC Reconfirming Good Morning Dr . Fauci, I am just reconfirming you for your segment on MSNBC this morning with Kendis Gibson and Cori Coffin . You ore hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue . Topics: -Coronavirus-infected Americans flown home against CDCadvice ht tps://w ww.washingt onpost .com/h ealt h/ coro navirus- diamond-princess-cru iseamer icans/2020/02/20/b6f 54cae-52 79-11ea-b119-4faabac66 74f st or y.ht ml -Decision to quarant ine cruise ship-was that a misstep? -Long term effects of decision to bring U.S. passengers back NIH-001 666 Please reply that you got this . Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE: contact at the studio tomorrow/MSNBC intv --------=--:-~ We absolutely will do. Thank you so much and thank you for your patience. We will be in touch first thing in the morning . From: Conrad, Patricia {NIH/NIAID) [E] (b)((;) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC} ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morning. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your ma ilbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv ---------=-c-c-= NIH-001667 We won't have an exact hit time until the morn ing BUT as of now, it's 7:30am . It might be 7:35am but that is the hit time. Cyndi wi ll send it to you by Sam tomorrow. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE:cont act at the studio tomorrow/MSNBC intv --------- Will you or Cyndi send exact hit tim e toni ght ? What is th e approx . t ime we will get that? Patrici a L. Conrad Pub lic Hea lth Analyst and Speci a l Assist ant to the Direc tor Natio nal Institute of Allergy and Infect ious Diseases The Nationa l Instit ut es of Health 31 Cent e r Drive, M SC 2520- Roo m 7A03 Bethesda, M ary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Goldne r, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6) Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] (b)(6)> Subject: RE: contact at the studio tomorrow/MSNBC intv -------== ~-========:=..~~ ----------- --------- Thank you so much From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 10:35 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/ NIAID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/ NIAID) [C] (b)(6); Lavelle, Jud ith (NIH/NIAID) [E] CbH6J> Subject: [EXTERNAL]RE:contact at the studio tomorrow/MSNBC intv ----------- NIH-001668 Great - t hanks. Please j ust let us know th e exact him t im e and we w ill have him arr ive 20 mins pri or. His cell is CbH6)and (b)(6) mine is Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who Is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6J> (b)(6) Deatrick, Elizabeth (NIH/NIAID) [CJ Cc: Robinson, Whitney (NIH/NIAID) [CJ (b)(6)> (b)(6J>; Lavelle, Jud ith (NIH/NIAID) [E] _, Subject: contact at the studio tomorrow/MSNBC intv Importance: High --------= = __________ ----------- Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The number at the office is 202 -885 -4800. Also, Cyndi Antoniak will be in touch wit h you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her numbe r is 212-664 - 1450 and her email is Cynthia .ant oniak@nbc uni.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney {NIH/NIAID) [CJ CbH6)>;Deatrick, Elizabeth {NIH/NIAID) [C] NIH-00166 9 CbH6J>;Lavelle, Jud ith (NIH/NIAID) [E] [EXTERNAL) RE:hi and request for Dr. Fauci this w eekend on MSNBC ---------Subject: CbH6J> Hi Shannah Sat urday M ornin g betw een 7:30 am ET- 8 am ET is best for Dr Fauci and wi ll need to be from th e NBC Studi o at 4001 Nebraska Ave NW st udio . He has a hard st op no lat er th an 8:15 am. Please send us th e onsit e contact name and numb er and firm hit t im e wh en you can . Thanks, -patty Patricia L. Conrad Public Health Analyst and Special Assistant to the Directo r National Institute of A ll ergy and Infectious The Nat iona l Institutes Diseases of Hea lth 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received !his e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4 :17 PM To: Conrad, Patricia (NIH/NI AID) [E) (b)(6)> --------=-c--c= Cc: Barasch, Kimberly (NIH/N IAID) [CJ (b)(6J>; Deatrick, Elizabeth (NIH/N IAID) [C] (b)(6) Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's terr ific and yes, that studio is best if he can join us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIAID) [E) Date: Thursday, February 20, 2020 4 :16---------- (b)( PM To: Goldner, Shannah (NBCUniversal) Cc: Barasch, Kimbe rly (NIH/N IAID) (CJ (b)(6)>; Oeatrick, Elizabeth (NIH/N IAID) (b)(6) Subject: [EXTERNAL] RE:hi and request for Dr. Fauci this weekend on MSNBC NIH-001670 [CJ I am sure we can make one of these work - will let you know tomorrow . We would do from the NBC Nebraska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e Nat ion al Institutes of Hea lth 3 1 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryl and 20892 (b)(6) 301-496-4409 fax Disclaime r: The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability fo r any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thu rsday, February 20, 2020 4:12 PM -------- To: Conrad, Patricia (NIH/NIA ID) [E)~======= Cc: Barasch, Kimberly (NIH/N IAID) [C]________ (b)(6) ~= (b) =(=6):>~= :,_ Cb) _<_ Deatrick, Elizabeth (NIH/NIAID) [C] Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance: High Patricia, hi, I hope all is well with you. Is Dr. Fauci available this weekend to be on MSNBCto discuss the latest re Corona virus https ://www .washingtonpost.com/ health/co ronavi rus-diamond -pri ncess-cruisea mericans/2020/02/20/b6 f54cae-5279- l lea -bl 19-4faabac667 4f story .htm I We'd like him on eit her on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin, or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good fo r him, we'll make work. Thank you so much for yo ur help in this matter. All the best, Shannah NIH-001671 Shannah Goldner MSNBC W: 212 -664 -1289 C: Cb)(6) NIH-001672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 11:39:06 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: MSNBC Reconfirming I just did reconfirm with a copy to you. Did you not get it? --------- From: Conrad, Patricia (NIH/NIAID) [E) Se nt: Saturday, February 22, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [E] -------=Subject: Fwd: MSNBC Reconfirming (b)(6)> (be)(= > You need to respond to this . It's in your on box Sent from my iPhone Begin forwarded message: From: "Antoniak, Cynthia (NBCUniversal, MSNBC)" Date: February 22, 2020 at 5:49:00 AM EST ------~~ To: "Fauci, Anthony (NIH/NIAID) [E)" CbH6)> Cc: "Goldner, Shannah (NBCUniversal)" , "Conrad, Patricia {NIH/NIAID) (E]" (b)(6) Subject: MSNBC Reconfirming Good Morning Dr. Fauci, I am just reconfirming you for your segment on MSNBC this morning wit h Kendis Gibson and Cori Coffin . You are hitting at 7:45am from the NBC News Bureau at 4001 Nebraska Avenue. Topics: -Coronavirus-infected Americans f lown home against CDCadvice ht tp s:/ /www .washingtonpost .com/healt h/ coronavir us-diamond-princess-cr uiseamer icans/2020/02/20/ b6f 54cae-5279 - 11ea- b119-4faabac66 7 4f story .htm l -Decision to quaranti ne cruise ship-was t hat a misst ep? - Long term effects of decision to bring U.S. passengers back Please reply that you got this. Thank you! Cyndi From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 3:09 PM To: Conrad, Patricia (NIH/NIAID) [El -------~~ NIH-001673 CbH6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:contact at the studio tomorrow/MSNBC intv We absolutely will do. Thank you so much and thank you for your pat ience. We will be in touch first thing in the morning . From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Friday, February 21, 2020 3:04 PM To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC); Fauci, Anthony (NIH/ NIAID) [E] (b)( > Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Ok- I am adding Dr Fauci to this email - please confirm to both of us in the morn ing. Thank you Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Inst itute of Allergy and Infectious Diseases The Nat ional Institutes of Heal t h 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute or Allergy and Infectious Diseases (NIAID } shall not accept lia bility for any statement made that are sender's own and not expressly made o n behalf of the NIA ID by one of its represent atives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 2:55 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)( > Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: RE: contact at the studio tomorrow/MSNBC intv --------~= We won't have an exact hit time until the morning BUT as of now, it's 7:30am. It might be 7:35am but that is the hit time. Cyndi will send it to you by Sam tomorrow . From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:48 PM ---------NIH-001674 (b)(6) To: Goldner, Shannah (NBCUniversal) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Will you or Cyndi send exact hit time tonight? What is the approx. time we will get t hat? Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National In stitutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The info rmation in this e-mail and any of its attachments is confidenti al and may contai n sens itive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e -ma il in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID} shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:42 AM To: Conrad, Patricia (NIH/NIAID) [E]_______ """ Cb "H= '"" > Cc: Robinson, Whitney (NIH/NIAID) [CJ (NIH/NIAID) [CJ ,;__;_ _ ___;_,.;_;,_::::~(b;::: )( :::;: 6).------- (b)(6)>; Deatrick, Elizabeth (b)(6); Lavelle, Judith (NIH/NIAID) [E] Subject: RE: contact at the studio tomorrow/MSNBC intv Thank you so much (b)(6) From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, February 21, 2020 10 :35 AM To: Goldner , Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [C] (b)( Deatrick, Elizabeth (NIH/NIAID) [C) (b)(6) Lavelle, Judith (NIH/NIAID) [E] ---------- (b)(6) Subject: [EXTERNAL]RE: contact at the studio tomorrow/MSNBC intv Great -thanks. NIH-001675 Please just let us know the exact him time and we will have him arrive 20 mins prior. His cell is (b)(6) and ------- mine is (b)(6) ------- Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he information in this e-ma il and any of its attachments is confident ial and may contain sensitive information. It shou ld not be used by anyone who is not the origina l intended recipient. If you have received this e-ma il in error plea se inform the sender and delete it from your mailbox or any other storage devices. National Institut e of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives . From: Goldner, Shannah (NBCUniversal) Date: Friday, February 21, 2020 10:29 AM --------~= > Cc: Robinson, Whitney (NIH/NIAID) ~-========:::::..-:;;;-;,-=, [C] Deatrick, Elizabeth To: Conrad, Patricia (NIH/NIAID) [El (b)( (b)(6J>; (NIH/NIAID) [C) ,;_ ___ ;;>---------- ;_;_..;..==-(b~) :;,; ~ (b)(6); Lavelle, Judith (NIH/NIAID) [El Subject: contact at the studio tomorrow/MSNBC intv Importance : High Patricia, hi, The contact at the studio in the morning is Natalia Abrams. The numbe r at the office is 202-885-4800. Also, Cyndi Antoniak will be in t ouch with you in the morning and send you an email about the segment and just to touch base. If you need to reach Cyndi before she reaches you, her number is 212-664- 1450 and her email is Cynth ia.anton iak@nbcun i.com . Thank you so much for making the interview work out, we appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El (b)(6) Date: Friday, February 21, 2020 9:06 AM To: Goldner, Shannah (NBCUniversal) Cc: Robinson, Whitney (NIH/NIAID) [CJ CbH6J>; Deatrick, Elizabeth {NIH/NIAID) [C) (b)(6)>; Lavelle, Judith {NIH/NIAID) [E] NIH-001676 (b)(6) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci th is weekend on M SNBC Hi Shannah Saturd ay M ornin g betw een 7:30 am ET - 8 am ET is best for Dr Fauci and w ill need t o be fr om th e NBCStudi o at 4001 Nebraska Ave NW studi o. He has a hard stop no lat er th an 8:1 5 am. Please send us t he onsit e conta ct name and numb er and fi rm hit tim e w hen you can. Than ks, -patt y Patricia L. Con rad Public Health Analyst and Specia l Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Cente r Dr ive, M SC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 30 1-496- 4 409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of A llergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not express ly made on behal f of the NIAID by one of its representatives. From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:17 PM To: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Cc: Barasch, Kimber ly (NIH/NIA ID) [C] (b)(6)>; Deatrick, Elizabeth (NIH/N IAID) [C) (b)(6) --------~= Subject: RE: hi and request for Dr. Fauci this weekend on MSNBC That's te rrific and yes, that st udio is best if he can jo in us. Thank you so much. Shannah From: Conrad, Patricia (NIH/NIA ID) [E] Date: Thursday, February 20, 2020 4:16 PM (b)(6) To: Goldner , Shannah (NBCUniversal) Cc: Barasch, Kimber ly (NIH/NIAID ) [CJ (b)(6) ; Deatrick, Elizabeth NIH-001677 (b)(6) (NIH/NIAID) [C) Subject: [EXTERNAL]RE: hi and request for Dr. Fauci this weekend on MSNBC I am sure we can make one of these work - will let you know tomorrow. We would do from the NBC Nebra ska Ave NW Studio. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mai l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Goldner, Shannah (NBCUniversal) Date: Thursday, February 20, 2020 4:12 PM To: Conrad, Patricia (NIH/NIAID) [E] ---------=- (b"'"" )( =6) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Deatrick, Elizabeth {NIH/NIAID) [C] (b)(6)> Subject: hi and request for Dr. Fauci this weekend on MSNBC Importance : High Patricia, hi, I hope all is well wi th you. Is Dr. Fauci available this weekend to be on MSNBC to discuss the latest re Corona virus https://www .washingtonpost.com/health/coronavirus -d iamond -princess-cruiseameri cans/2020/02/20/b6 f54cae-5279- l le a-b 119-4faa bac6674f sto ry.htm l We'd like him on either on Saturday, in the 7:30am to 8am half hour, with Kendis Gibson/Cori Coffin , or on Sunday in the 12pm or 1pm hour with Alex Witt. Whatever day/hour that is good for him, we'll make work. Thank you so much for your help in this matter. NIH-00167 8 Allthe best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) NIH-001679 From: Fauci, Anthony (NIH/NIAID) [El Sat, 22 Feb 2020 02:39:22 +0000 To: Morens, David (NIH/NIAID) [El Subject: FW: So what do you guys think? (I no it 's not influenza, but a lot of your 2007 conclusions seem very valid now ...) Date: David: Please respond to this person. Thanks, Tony -----Original Message ----From: ----------------------------~~ 00( Date: Friday , February 21, 2020 9:32 PM To: Fauci, Anthony (NTH/NIAlD) [E] (b)(6) Subject: So what do you guys think ? (Tno it's not influenz a, but a lot of your 2007 conclusions seem very val id now ...) Dear David Morens, dear Anthony Fauci , J realise it is not an influenza virus, but the outlook of your 2007 paper ("The 1918 lntluenza Pandemic: Insights for the 21st Century") seems to me to be very valid for the current coronavirus outbreak. Or put differently - your statements and concerns from then mostly coincide with my thinking and wonies now ... :( . So a question - what is your thinking now? Are the hospitals you're affiliated w ith hiring additiona l staff (yet)? Any personal preparations? Good luck to you and all the best for those close to you, kind regards , Sean Scherer P.S. I guess part of the the reason I'm asking is, because I (a non-institutionally affiliated biologist), am in touch with the university-hospital here (b) ( Germany), but my concerns are so far falling on deaf ears ... But also just reading the paper and seeing others come to the same conclus ions - albeit on more theore tical grounds and multip le years ago - made me want to reach out. Plu 5 I guess I'm simp ly curious about what you think ! NIH-00168 1 From: Date: (b)(6) To: Cc: Subject: Fri, 21 Feb 2020 14:38:56 -0500 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Re: Work related question You are correct. No chance that I would accept. Thanks On Feb 21, 2020, at 2:23 PM, Billet , Courtney (NIH/NIAID) [E] Cb)(6) wrote: In the interest of fu ll disclosure: Stephanie Cb)(6) used to work here at HHS and is now a VP with the American College of Preventive Medicine . For the life of me I couldn't see you saying yes to a weekend trip to Denver in May, and I wou ld hate to have them waste their time sending an invite when they could be pursuing someone more likely to accept. Hope this is OK. From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, February 21, 2020 2:18 PM To: Stephanie Marshall Subject: RE:Work related question ----------~~ ------------- > (b)( Hi -good to hear from you! I hesitate to speak definitively for him and his scheduler, but to be perfectly honest I think it's really unlikely that'd he'd be able to accept a speaking invite for Denver. The schedule is insane for the foreseeable future and isn't letting up on the weekends. He's turning invitations down left and right, unfortunately - especially those involving travel! ------------- From: Stephanie Marsha ll Date: Friday, February 21, 2020 1:51 PM To: Billet, Courtney (NIH/NIAID) [E] ______ (b)(6) (b -=-= )'""' (6) = > Subject: Work related question Hi Courtney, I hope you're doing well despite the ongoing craziness whether it's coronavirus or politics. Yikes, these are unsett led t imes. I have a quick question for you. Our annua l meeting is May 14 - 17 in Denver. Many of the sessions are in place but there's talk about doing a session around NIH-001682 coronavirus and invit ing Dr. Fauci as the speaker. The meeting is a Thursday through Sunday and they 're look ing at inviting him to speak potentially on Sunday morning. Is this something he would even consider and would he commit this far out given everything that's going on? Any quick thoughts you might have would be helpful. Thank you, thank you! Have a great weekend. Stephanie NIH-001683 (b)(6) From: Date: To: Cc: Subjec t: Fri, 21 Feb 2020 10:40:17 -0500 Collins, Francis (NIH/OD) [E] Hallett , Adrienne (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [El Re: FYI on Senate staff visit Thanks, Francis. On Feb 21, 2020 , at 10:30 AM, Collins, Francis (NIH/OD) [E] (b)(6) Hi Tony, I got asked by Alex Keenan what the NIH needs for the coro navirus response. I said that this had been looked at with great care by you and your staff . If you are asking me for technical assistance, I said, we need about (b)(5)for FY20-21, and more in the long run. ASFRwas in the room but did not have a visible seizure. Just thought you'd want to know before you meet with the staffers later today. FC NIH-001684 From: Date: To: Cc: _______ -------~= Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 14:31:08 +0000 Donna Jacobsen Conrad, Patricia (NIH/NIAID) [E);Greg Folkers Cb _)_C6) _. );Marston, Hilary (NIH/NIAID) [E) RE: CROI COVID 19 Session; Tuesday March 10 lunch Donna: Thanks for the note . I will be able to provide a 15 minute video with slides that discusses the NIH/NIAID efforts to study the novel coronavirus and to develop countermeasures in the form of diagnostics, therapeutics, and vaccines. Your team can work with Patty Conrad, Hilary Marston and Greg Folkers on the logistics. In the meantime, we will prepare the video. Best regards, Tony Anthony S. Fauci , MD Director Nation al Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the origina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage device s. The Nationa l Institute of Allergy and Infectiou s Diseases (NIAID) shall not acce pt liability for any statem ents made that are the se nder's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Thursday, February 20, 2020 8:53 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch Importance: High Dear Dr Fauci: W e've had a lot of discussion around our COVID-19 session today. An idea t hat came up was possib ly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDT on Tuesday, March 10 if you have that time avai lable, or have you send in a video recorded present ation a day or 2 before that we can show at the session. Having some way to commun icat e the NIH-001685 high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is like ly not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https ://www .iasusa .o rg About IAS- USA : Established in 1992, the IAS-USA is a not-for-profit , professional education organization. The mission of the IAS -USA is to improve the prevention , treatment , care, and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infec tions through high-quality, relevant, balanced , and needs-orien ted educatio n and information for practitioners who are actively involved in medica l care . The organization's educational activities are particular ly intended to bridge clinical research and patient care . Confident iality Notice: This e-mail and its attac hments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing , or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanent ly delete this e-mai l and any attachments. From: Fauci, Anthony (NIH/N IAID) [E] ________ Date: Thursday, February 20, 2020 7 :12 AM _> Cb _C6) _ NIH-001686 To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, MD Sharon Hillier PhD --------======~~-:------:---:-:.:======~~ (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday March 10 lunch ------------- (b)(6) >; (b) (6) Hoxie, James --------- (b)(6); Kevin Bowen Donna: Thanks for t he note. Unfortunat ely, I need t o be in Washington, DC on March 10, and so I will regrettabl y have to decline your kind inv itation . Thank you f or thin king of me. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/ NIAID) (E] (b)(6) Cc: (b)(6); 'Elaine J. Abrams, M D Sha-ro- n ---:-'. H~il~lie_r_P ~h- D -;::::===:;....-----...:...--======. -------=-:--:= ------~==-------------~= -------=====~~------:;;::::====~~ (b)(6); Benson, Connie ------------- (b ~)~(6) ~ >;~H ~o- x~ie - ,~J-a_m_e_s___ -------- ;, (b)(6) _ (b)(6)>; Kevin Bowen Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID 19 at CROI. It wi ll be on Tuesday, M arch 10, during the lunch break ; the init ial general structure will be a 10to 15- minute overview (CDC), a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/ NIH is doing and planning. We thought that this being NIH-001687 one of the first large medical conferences in infectious diseases this year, that we address COVID 19 at CROI We know that this is terribly last minute , but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROI is in Boston, Mar ch 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics . Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donn a M. Jacobsen Executive Director /President Internationa l Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa .org ~ ACCME About IAS- USA : Established in 1992, the IAS-USA is a not-for-p rof it, professional education organization . The mission of the IAS-USA is to improve the prevention , treatment , care , and quality of life for people with or at risk of HIV , hepat itis C virus , or other viral infec tions through high-quality , relevant, balanced, and needs -oriented education and information for practitioners who are actively involved in medica l care . The organization's educational activities are partic ularly intended to bridge clinical research and patient care. Confident iality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for delivering this message to the intended recipien ts, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strictly prohibited . If you have received this transmission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001688 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 13:33:20 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: FDA Request FDA Clearance Letter.pdf, Nepal Corona Vi rus Paper.pdf Date: To: Subject: Attachment s: Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeff Fischer (b)(6) Date: Friday, February 21, 2020 8:30 AM To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) (b)( >; Khabbaz, Rima (CDC/DDID/NCEZID/0D) (b)(6)'> ; Fauci, Anthony (NIH/NIAID) [E)______ Cc: Chris Helm Subject: FDA Request -------- (b) (6) ..,... (b"'"" )( =6) > Ors Messonnier, Khabbaz, and Fauci, The Center for Devices and Radiological Health at the FDA suggested that we reach out to COVID-19 EUA develo ers to (b) (4~ (b) (4) NIH-001689 (b) (4) Respectfu lly, Jeff Jeff Fischer President Longhorn Vaccines and Diagnostics LLC 2 Bethesda Metro Center Suite 910 Bethesda, MD 20814 (b)(6) NIH-001690 Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202010:47:53 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Fwd: Notes for NIH.docx From: Date: To: Subject: Attac hment s: Pleasehandle. From: RICK SAWAYA (b)(6)> Date: Friday, February 21, 2020 1:48 AM To: Fauci, Anthony (NIH/NIAID) [E) .------ -,,Cb --. H= >; Cassetti, Cristina (NIH/NIAID) [E) (b)(6) Subject: Fwd: 2202020 Dr. Fauci: This is Dr. Rick Sawaya : Dr. Tom Betz is (b)(6) and his training is more in line with yours than mine. He submitted this mini-endorsement to you for me and my work. He has seen most of my works and the NIH data protocol from 2016-2017. I think his background gives credibility to my ideas and lends a public health opinion which I did not have until calling him . Hope you enjoy th is. I have treated cancers, herpes, acne easily with this stuff and honestly and confidentially it will do anything but your income tax. Thanks, Rick Sawaya M.D. (b)(6) call between 10am and 10pm EST, ---------- Forwarded message --------From: Tom Betz (b)(6) Date: Thu, Feb 20, 2020 at 10:32 PM Subject: Re: To: RICKSAWAYA ---------- (b)(6) Rick, I am attaching suggested notes for NIH. They may t hink we're both crazy but I imagine you have already been down that road and I'm interested to see what happens . Hang in there, NIH-001698 Tom On Tue, Feb 18, 2020 at 2 :01 PM RICK SAWAYA ---------- THIS HAS THE CELL WITH LEARS SIGNATURE ABOVE IT AND A CYSTEINE RANDOM DIAGRAM NIH-001699 (b)(6 b wrote: From: Date: To: Subject: Impo rt ance: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 02:42:07 +0000 NIAIDODAM FW: CROICOVID 19 Session; Tuesday March 10 lunch High Let us discuss. From: Donna Jacobsen Se nt: Thursday, February 20, 2020 8:53 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [El!. =======~ (b)(6)> (b""" )('=" 6)> Subject: RE: CROICOVID 19 Session; Tuesday March 10 lunch Import ance: High Dear Dr Fauci: We've had a lot of discussion around our COVID-19 session today. An idea that came up was possibly having you do something remotely. Either a live feed in from your office at approximately 1:05 PM to 1:20 PM EDTon Tuesday, March 10 if you have that time available, or have you send in a video recorded presentation a day or 2 before that we can show at the session. Having some way to commun icat e the high priority NIH/NIAID has on developing a vaccine and treatment would help bring the content togethe r. We know this is likely not possible, with the very short notice and your even more tremendously busy schedule around all of this. But it 's worth the ask. Please let me know if you think either of these is possible. And Patty, sorry for butchering your email address earlier . Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA Executice Manager, CROI 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 NIH-001700 https://www .iasusa.org About IAS- USA : Established in 1992, the IAS-U SA is a not-for-prof it, professional educat io n organizat ion . The mission of the IAS-USA is to improve the prevention , treatme nt, care , and qua lity of life for people with or at risk of HIV , hepatitis C virus , or other vira l infections through high-quality , relevant, balanced , and needs-orien ted education and information for practitioners who are active ly involved in medica l care . The organ ization's educational activities are particularly intended to bridge clinical research and patient care. Confid entiality Notice : This e-mail and its attachmen ts may contain priv ileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent respons ible for deliveri ng this message to the intended recipien ts, you are hereby notified that any review , dissemination , distribution , printing, or copying of this e-mail message and/or any attach ments is strict ly prohibited . If you have received this transmissio n in error, pleas e notify the sende r immediate ly and permanently delete this e-mail and any attachments. ---------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Thursday, February 20, 2020 7:12 AM To: Donna Jacobsen Cc: (b)(6) 'Elaine J. Abrams, M D Sharon Hillier PhD _..,,...===~~;--::-------::-----:---:======~ < (b)(6); Benson, Conn ie Subject: RE: CROI COVID 19 Session; Tuesday M arch 10 lunch (b)(6)] (b)(6) (b)(6)>; Hoxie, James ~ (b)(6) >; Kevin Bowe n Donna: Thanks for t he note . Unfortunat ely, I need t o be in Washingt on, DC on March 10, and so I will regrett ably have to decline your kind invit ation . Thank you f or thin king of me. Best rega rds, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-00170 1 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Donna Jacobsen Date: Tuesday, February 18, 2020 8:09 PM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> ---:-:-----:-:-::-.::::=t.....------------'="'""= Cc: (b)(6)'ElaineJ. Abrams, MD Sharon Hillier PhD Cb)(6) >; Hoxie, James (b)(6); Benson, Connie (b)(6); Kevin Bowen Subject: RE:CROICOVID19 Session;Tuesday March 10 lunch (b)(6) --------======~~-:-----:---:-.:======~ ~ ------------- --------- Dear Dr Fauci: As I mentioned on the phone, we just today decided that we will have a special session on COVID19 at CROI. It will be on Tuesday, March 10, during the lunch break; the init ial general structure will be a 10to 15- minute overview (CDC),a 25-min talk by Ralph Barac (UNC) about the viro logy of coronavi ruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large medical conferences in infectious diseases this year, that we address COVID19 at CROI We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update. CROIis in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication with details and work with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be able to join us. Best, Donna Donna M. Jacobsen Executive Director /President International Antiviral (formerly AIDS) Society-USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415-544-9400 https://www .iasusa.org NIH-001702 About IAS-USA: Established in 1992, the IAS-USA is a not-for-profit , professional education organization . The mission of the IAS-USA is to improve the prevent ion, treatment , care , and quality of life for people with or at risk of HIV, hepatitis C virus , or other viral infections through high-quality, relevant, balanced , and needs-oriented education and information for practitioners who are actively involved in medical care. The organization's educational activities are particularly intended to bridge clinical research and patient care. Confidentiality Notice: This e-mail and its attachments may contain privileged and confidentia l information intended solely for the use of the IAS-USA and the recipient(s) named above. If you are not the intended recipient, or the employee or agent responsible for delivering this message to the intended recipients, you are hereby notified that any review, dissemination , distribution , printing, or copying of this e-mail message and/or any attachments is strict ly prohibited . If you have received this transm ission in error, please notify the sender immediately and permanently delete this e-mail and any attachments. NIH-001703 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 21 Feb 2020 01:47:03 +0000 McNeil Jr, Dona ld G RE: question re the Wash Post story Donald: You know that I always answer your calls and e-mails, but this one I want to stay away from. Sorry. Best, Tony From: McNei l Jr, Donald G Date: Thursday, February 20, 2020 4:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: question re the Wash Post story ------~~ (b)(6) Now that I've had a chance to read the whole story -- after editors finished whirl ing --1 see it also contains these grafs: Are they accurate? Thanks During one call, the CDC's principal deputy direc tor , Anne Schuchat, argued agains t taking the infected Americans on the plane, according to two participants. She noted the U.S. government had already told passengers they would not be evacuated with anyone who was infected or showed symptoms. She was also concerned about infection control. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, who was also on the calls, recalled saying her points were valid and should be considered. But Robert Kadlec, assistant secretary for preparedness and response for the Department of Health and Human Services and a member of the coronavirus task force, pushed back: Officials had already prepared th e plane to handle passengers who might develop symptoms on the Jong flight, he argued. The two Boeing 74 7s had 18 seats cordoned off with 10-foot-high plastic on all four sides. Infectious disease doctors would also be onboard . On Thu, Feb 20, 2020 at 4:24 PM McNeil Jr, Donald G wrote: Hi, Tony: The Washington Post has just put up a story saying that the 14 infected passengers on the buses containing 238 American passengers from th e Diamond Princess were flown home AGAINST the CDC's advice . And that the States Department overru led the CDC on this. Can you confirm whether that's true? NIH-001704 Thanks ... Donald Story contains these cruc ial grafs: In Washington, where it was still Sunday afternoon, a fierce debate broke out: The State Department and a top Trump administration health official wanted to forge ahead. The infected passengers had no symptoms and could be segregated on the plane in a plastic-lined enclosure. But officials at the Centers for Disease Control and Prevention disagreed, contending they could still spread the virus . The CDC believed the 14 should not be flown back with uninfected passengers. "It was like the worst nightmare," said a senior U.S. official involved in the decision, speaking on the condition of anonymity to describe private conversations. "Quite frankly, the alternative could have been pulling grandma out in the pouring rain, and that would have been bad, too." Donald G. McNeil Jr. Science Correspon dent (i;~t:Xt\u Uork{;imts Tel: +l 212 556 1142 mcneil@nytim es.com Articles: https://www .nytime s.com/by /donald-g-mc neil-jr NIH-001705 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 2020 00:13:55 +0000 Richard Al len Johnson RE: 02.20.2020 Thursday Dick: Tha nks for the note. Always good to hear from you. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-c-c= From: Richard Allen Johnson Date: Thursday, February 20, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: 02 .20.2020 Thursday -------- (b)(6) (b)( >; Sandra Goldste in --------- (b)(6) Hi, Tony, ------------- (b) (6) this week. We watched a life size ASF as you discussed and reassured us about Covid-19. You are simply the best. Were you ru nning for president, I am sure t hat you would win the yote . Don't forget our lunch in Boston . Best, Dick NIH-001706 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:48:29 +0000 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El FW: Urgent- Phone Interview Request on Coronavirus Done! Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail i n error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Qi Zhang Date: Thursday, February 20, 2020 3:16 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Urgent- Phone Interview Request on Coronavirus ------~~ --------- = Dear Dr. Fauci, Good afternoon . I am Olivia Zhang with Caixin Media, which is the front-liner of the Coronavirus reporting in China. We spoke at the very beginning of the virus and I wanted to talk to you regarding the latest situation, especially from test, treatment point of view. I also left you a voice message. Feel free to call me via (b) ( whenever you're free . I look forward to hearing from you. Best, Olivia Qi ZHANG {Olivia) U.S. Correspondent Caixin Media Company Limited NIH-001707 Email: qizhang@caixin.com Mobile:-+(b)(6) Twitter: @zhang_qiii www .caixin.com I caixingloba l.com NIH-001708 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 23:28:04 +0000 Achenbach, Joel RE: quick question: when does an epidemic become a "pandemic" officially? It is impossible to predict at this point if the current outbreak will progress to a true pandemic. The future of this outbreak and whether it will progress to a pandem ic will be determined by two factors: 1) the degree to which China controls infect ions in China, which will ultimately impact how many infect io ns leak out to other countries in the world. 2) The success or not of other countries that have received travel-related cases from China in preventing the development of sustained transmission of infections in their own country. If these other countries are successful in containing the transmissions, then a pandemic will be avoided. If a large number of countries are unsuccessful in preventing sustained multi -generation transmissions , then we could witness the next pandemic . Anthony S. Fauc i, MD Dire cto r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel Date: Thursday, February 20, 2020 6:11 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: RE: quick question: when does an epidemic become a "pandemic" officially? Oh....and...the big question: How likely is it that covid-19 will become a pandemic? Would love an onthe-record assessment. Thanks...joel -------- (b)(6)> From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 20, 2020 6:06 PM To: Achenbach, Joel Subject: RE: quick question: when does an epidemic become a "pandemic" officially? NIH-001709 ICAUTION: EXTERNALSENDER Joel: There are many iteration s of t he definition of a "pandemic" . However , one that I use that is simple and under standable is as follows: An outbreak of a serious infectious disease with substantial global health consequences (usually one that has never before been experienced by the human populat ion) that is transmitted readily from person to person and where there is sustained transmission (i.e . mu ltiple generations of person to person to person) in mu ltiple countries and regions of the world. In this regard, the coronavirus outbreak in China is an "epidemic" in China, but it is not yet a pandemic since there is not "sustained" person to person transmission throughout the world. There are infections in other countries (more than 25 countries), but these started as travel relate d cases from China and although there are several human to human infections in these other countries, these infections have not yet been "sustained". If we start seeing sustained, multiple generations of transmissions in many countries throughout the world, then the outbreak will have progressed to fill the criteria of a true pandemic. Hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its atta chments is confidential and may contain sensitive information . It should not be used by anyone who is not the origi nal intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Achenbach, Joel NIH-001710 (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] Subject: quick question: when does an epidemic become a " pandemic " officia lly? Dear Tony Fauci: Hi! Busy times . Hope you are well. Can you explain to me how we will know if and when covid -19 has become pandemic, versus whatever you' d call the current situatio n? Just in general , what ' s the defin ition of a pandemic? Thank you ... best, Joel (and thanks for calling me back last weekend , sorry I missed you ) NIH-001711 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/ NIAIO) [E) Thu, 20 Feb 2020 16:45:39 +0000 M ichael Gerson RE:Tony, I'm still working on th is, but need your react ion Gerson wi t h minor Fauci edits .docx Mike: Thanks for sending this. It looks good . I have copied it to a WORD document and have made some minor suggested edits for your consideration. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michael Gerson (b)(6)> Date: Thursda y, February 20, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Tony, I'm still working on this, but need your reaction ------~~ Meanwhile , on the other side of the earth, th ere have been 73,000 cases of coronavirus and more than 2000 deaths. This leaves American hea lth experts hoping that the number of infections has been dramatically underreported. That is not a typo. If the current nu1nbers are close to accurate, it indicates a coronavirus mortality rate upwards of 2 percent. The morality rate for the seasonable flu is gen erally .1 percent. The mortality rate for pandemic flu is .3 percent. The particularly deadly flu pandemic of 1918 - NIH-001714 which took the lives of more than 100 million people around the world had a mortality rate of 1.8 to 2 percent. So, if 2000 deaths is the numerator, scientists hope that the denominator is actually much larger. And that is probable, given the likelihood that there are many more people who have the infection but don't know it, or are not showing symptoms. The good news? The outbreak started in a single location and seems largely contained there. There have been several hundred cases in more than 25 countries outside of China. But the overwhelming majority have been travel related. The containment measures of Singapore, Hong Kong and Japan - which have the most cases - seem to have been successful. Of the 15 American cases (before the arrival of the cruise ship passengers), 13 are travel related. The two others are spouses of people in that group. We still have not seen widespread, sustained transmission from person to person outside of China. The Chinese reaction to the virus has shown the weaknesses and advantages of authoritarianism. The immediate response of a system built on fear is to a problem like this one is denial and deception. No one wants to carry bad news. So local Chinese officials spent the first week of the outbreak - as the disease was spreading under the radar - insisting that the transmission of the virus was all animal to human. But only in a society like China could you have the effective lockdown of 50 million people, including the entire city of Wuhan, to slow the spread of the disease. Public health officials in most places - who are required to balance health needs with civil liberties - would not even consider such a measure. Yet it appears to be working. The danger? "All that is needed is for a few countries in the developing world that can't contain the coronavirus," Tony Fauci told me. "This could be the second wave of the pandemic." Pandemic diseases tend to attack the weakest links - the most vulnerable health systems - in the global chain. If there is sustained transmission in those places , says Fauci , "even countries with best practices will suffer." Countries in Africa are of particular concern. There are millions of Chinese in Africa, and many Africans study in China. Countries such as Ethiopia, Senegal and South Africa seem to be doing a good job at testing random samples for coronavirus in key cities. But Liberia? Guinea? Sierra Leone? Seldom has there been a stronger argument for American global engagement to strengthen African health systems, which constitute part of own immune system against pandemics. Seldom has there been a better NIH-001715 argument to abandon "America First" posturing and to recognize that our own fate is closely tied to the fate of other nations. Much about the future course of the disease depends on the answer to a scientific question: Is someone who has the virus but lacks symptoms - or has symptoms so mild they hardly notice - capable of transmitting the virus to others? "It looks like the answer is yes," says Fauci. Which would make the virus far harder to control. "We may find that the virus is highly transmissible, but less lethal than we thought in the beginning," Fauci told me . In this case, the danger would be similar to a particularly bad influenza. And the outbreaks could be seasonal, like the flu as well. "I would not be surprised if that happened," Fauci concluded. NIH-001716 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 15:15:05 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inquiry/suggestion re Corona virus-> Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alan DiCara Cb)(6) Date: Wed nesday, February 19, 2020 8:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: NIAID Ocpostoffice (NIH/NIAID } Subject: inqu iry/s uggestion re Corona virus-> -----~~ 2.19.2020 Dear Dr Fauci, Thanks so much for being who you are and for dedicating your life to protecting all of us. I write because I saw your interview on PBS tonight and had a question pertaining to denominators and numerators. Please know that I profess absolutely no expertise in areas pertaining to biology nor medicine nor disease and while I understood and agree with your estimation that the fatality rate of the Corona virus to date may be somewhat inflated of the number of cases is understated, I have a related NIH-001717 question for you regarding info I was able to find at this site https://www .worldometers.info/coronav irus/ Regarding data this site reports, among many things, and as one scrolls down, that the 'number of active cases' reported today is 57,228 and the number of these that are 'serious or critical' is 12,064. In a worst case scenario, and taking the 12,064 as the numerator and dividing it by a denominator of 57,228, we get 21 .08, or about 21 %, much higher that the 1% based on total deaths over total cases so far. Of course this is not fair but my question is this: can we know better how many of the patients (cases) who are 'serious or critical' and still being treated will recover? Thanks much for any replyAlan DiCara, Winsted, CT NIH-001718 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 20 Feb 2020 12:39:25 +0000 David Katz RE: CoronaVirus Epidemic -- a Thought David: Thanks for the note. I hope that all is well with you. Although allogeneic/semiallogeneic blood transfus io ns could be an interesting approach to serious COVID19 disease, there are a number of existing drugs such as remde sivir (nucleotide analogue) and Kaletra (protease inhib itor) that have some pre-clinical activity against the virus and these are now being tested in randomized clinical trials. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Hea lth Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: David Katz Cb)(6) Date: Wed nesday, February 19, 2020 6:02 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: CoronaVirus Epidem ic -- a Though t ------- (b)(6)> Dear Tony, It has been some time since we last spoke, but this current catastrophe has provoked my thinking about possible therapeutic interventions that could be immediately employed -- in advance of therapies/vaccines that will take NIH-001723 many months to create. And I need to share those thoughts with you. My suggestion is to treat actively-infected, and acutely ill, patients (under carefully controlled procedures) with allogeneic/ semi-allogeneic blood transfusions . The resulting GVHD response should theoretically combat, and eradicate the viral infection. I look forward to your thoughts on this suggestion. With best wishes to you and your family, David NIH-001724 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 10:51:23 +0000 To: Conrad, Patricia (NIH/NIAID) [El Cc: Mars ton, Hilary (N IH/NIAID) [El Subject: FW: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARD TELECONFERENCE TODAY FYI (b)(6)> ---------Date: Thursday, February 20, 2020 2:00 AM From: Amelie RIOUX To: As Sy (b)(6)>; Gro Harlem Brundtland (b) (6); 'Dzau Victor' ------- (b)(6); Chris Elias (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)(6); Fore Henrietta (b)(6l:>; Gao Fu (b)( ; Gashumba Diane (b)(6); Ilona Kiekbusch (b)(6); Suzuki Yasuhiro (b)(6) CbH6J ; Vega Morales Jeanette (b)(6); VijayRaghavan Krishna swam y (bT(6h ; Skvortsova Veronika (b)( Cc: (b)(6)Tore Goda! (b)( ; Godal, Tore (b)(6) Subject: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSED BOARD TELECONFERENCE TODAY Import ance: High =======:::'-= ======== ~= -.-:------======-- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLAND AND MR SY Dear Board Members, We would like to hold a teleconference of the Board today, 20 February at 13:00 Geneva time. The agenda for the call would be as follows: • Short update and stock taking on the coronavirus outbreak ; • Functioning of the Secretariat and improving effect iveness of the Board ; • Way forward Please note that this call wou ld be a closed discussion, for Board members only. We would appreciate if you could confirm your partic ipation to Amelie Rioux (at -------- We will share with you shortly the call-in details . Thank you for your support and continued engagement . We look forward to the call. With kind regards , Gro and As NIH-001725 (b)(6) From: Date: To: Subject: Thanks, Sharon. and integrity. Best regards, Tony Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 03:43:40 +0000 Sharon Rockefeller RE:This evening's broadcast It is always a pleasure to be on the PBS NewsHour. They are high on honesty From: Sharon Rockefeller Date: Wednesday, February 19, 2020 8:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: This evening's broadcast ------~~ (b)(6) Dear Dr. Fauci, Thank you, once again, for appearing on the PBS News Hour and for treating so many Coronavirus patients. Your gift of calm and clear explanations to normal people is unparalleled. Please do not exhaust yourself as you help so many others. (b) (6). Very sincerely , Sharon Sent from my iPhone NIH-001729 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 00:54:10 +0000 To: Crawford, Chase (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [El Subject: RE: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Attachments: Draft NIAID insert for COVID-19 hearings_to ASF - with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone . (b)(6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crawford , Chase (NIH/NIAID) [El Date: Wednesday, February 19, 2020 6:16 PM -----To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6) ~= (b)(6) Cc: Billet, Courtney (NIH/N IAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)( ; Haskins, Me linda (NIH/NIAID) [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [El (b)(6)> Subject: Requesting your assistance: Draft NIAID Insert for Upcoming Coronavirus Hearings Dr. Fauci: In preparation for the upcoming COVID-19 hearings of the House Committee on Energy and Commerce Health Subcommittee and the Senate Committee on Health, Education, Labor and Pensions, we have drafted the attached N1AID insert for inclusion in the combined HHS statement for the record. The Department plans to use the same combined statement for both the House and Senate hearings. NIH-001735 The attached draft ha s been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston , as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. The Deparb.nen t has asked to receive your statement by COB tomorrow, Feb . 20th . Thank you for your help. Cha se Chase Crawford, D.V.M., M.S. Public Health Analyst Legislat ive Affairs and Correspondence Ma nagement Branch Office of Com municat ions and Government Relations NIAID/NIH/DHHS Bldg. 31, Room 7A17, MSC2520 Bethesda, MD 20892-2520 (b)(6J Disclaim er: The information in this e-mail and ony of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infec tious Diseases shall not accept liability for any statements made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001736 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 19 Feb 2020 23:03:23 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: BioCentury coverage of mAbs to treat COVID-19 Please han dle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Karen Tkach Tuzman Date: Wednesday, February 19, 2020 5:56 PM -------=-:--:= To: Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: BioCentury coverage of mAbs to treat COVID-19 Import ance: High Dear Dr. Fauci, I hope all is well. BioCentury is doing a roundup of companies and institutions developing antibodies against the SARS-CoV-2 virus to treat patients with COVID-19. Since you told my colleague Steve Usdin NIAID is developing its own mAbs against the virus, we'd like to include informat ion about that program in our roundup . Would you or one of your colleagues be able to answer the following questions? Any information you could share by 5 PM Pacific Time on Thursday, Feb. 20 would be greatly appreciated . 1. Are your mAb candidates being developed against specific targets on SARS-CoV -2? If so, what are those targets? 2. What platforms or processes are you using to identify mAb candidates? 3. Do you have multiple mAb programs against SARS-CoV-2proceeding in parallel, and if so, how are they distinguished? NIH-001737 4. What is that status of each of your mAb programs? For example, have you nominated any lead candidates, are you awaiting patient samples, etc.? 5. Do you have any metrics on lead candidates available yet, such as neutra lization titers? If so, what are they? All the best, Karen Karen Tkach Tuzman, Ph.D. Head, Discovery & Preclinical Development Associate Editor, BioCentury Inc. 650-595-5333 x 144 (office ) www .biocentu ry.com Notice: This communication (including any attachments) constitutes an electronic communication within the meaning of the Electronic Communications Privacy Act, 18 USC2510, and its disclosure is strict ly limited to the recipient(s) intended by the sender of this message. This communication (including any attachments) contains proprietary information, is protected under U.S. and foreign copyright and other intellectual property law, and may contain confidential material for the sole use of the intended recipient. Any unauthorized review, use, disclosure, dissemination, copying or distribution of this communication (including any attachments), or any of their respective contents, is strictly prohibited. If you are not the intended recipient, please contact the sender by return email and destroy all copies of the original message. NIH-001738 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAI0) [E) Wed, 19 Feb 2020 20:27:04 +0000 Conrad, Patricia (NIH/NIAID) [El Greg Folkers (b) (6) FW: Invita ti on to Speak lnvitation_Dr. Anthony Fauci.pdf Patty/Greg: Let us discuss. ASF Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail · (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Crow, Hilary Date: Wed nesday, February 19, 2020 12 :35 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Speak -------- (b) (6)> Dear Dr. Fauci, I'm writing to share the attached invitation with you to speak at the U.S. Chamber Foundation's program on March 10 on the future of medicine. Our audience of CEOs, market leaders, and opinion leaders would be thr illed to learn more about your perspective on the future of medicine, current issues like the Coronavirus , and futu re challenges in health and med icine. Please let me know if you have any questions. I'm happy to schedule a quick call to provide more detail over the phone with you o r someone on your team. I hope you will be able to join us. NIH-001739 Best, Hilary Hilary Crow Executive Director, Programs U.S. Chamber of Commerce Foundation 1615 H Street, NW I Washington, DC I 20062-2000 Office: 202.463.5710 (b)( Mobile: ---G U.S.Chamber ofCommerce Foundation -~'& www .uschamberfoun dation .org NIH-001740 From: Date: To: Cc: (NIH/NIAID) [El Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 16:51:27 +0000 Marston, Hilary (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Handley, Gray Subject: RE: Invitat ion to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC If they accept two people, you should go with Gray. Obviously, you should make no commitments and when asked about policy issues, say that you will convey to me and we will get back to them. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marston, Hilary (NIH/NIAID) [E] (b)(6)> Date: Wednesday, February 19, 2020 10:09 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)( ; Folkers, Greg (NIH/NIAID) [El (b)(6); Handley, Gray (NIH/NIAID) [E) (bH Subject: Re: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC --------- Have you had a chance to discuss this world bank conference? You, Cliff and Libby received invites. As Gray has mentioned, this is a pledging conference, so we will need to be prepared to address funding (the person that attends wou ld need to be in sync with you on that). Obviously Cliff is on travel. Who would you like to have at the conference, if anyone? -h ilary NIH-001741 From: Anthony Fauci (b)(6)> Date: Friday, February 14, 2020 at 9:25 PM To: NIAID AM Subject: FW: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thu rsday, Februa ry 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Let us discuss. From: Feng Zhao Date: Friday, February 14, 2020 5:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------- --------- ~= (b)(6) Cc: (b)(6); Mu kesh Chawla ; Rocio Schmunis ; Adrienne Kate Mcmanus ; Gabrielle Lynn Williams ; WB Health Events ; Muhammad Ali Pate Subject: Invitation to the Consultation on Financing Coronavirus Disease 2019 (COVID-19) Vaccine Development I Thursday, February 20, 2020 I 9:30am to 1:30pm I World Bank Headquarters, Washington DC Dear Dr. Fauci, On behalf of the World Bank health team, in coordination with the Coalition for Epidemic Preparedness Innovations (CEPI),it is our pleasure to invite you to a half-day consultation on Financing Coronavirus Disease 2019 (COVID -19} Vaccine Development . The meeting is set to take place on Thursday, February 20, 2020 from 9:30am to 1:30pm at the World Bank Offices in Washington DC (located at 1818 H St NW) on floor C2, conference room MC C2-125. As you know, the novel Coronavirus outbreak, which started in Wuhan, China, is evolving rapidly. As of today, the number of confirmed cases has increased significantly to over 60,000 and the virus has reached 25 countries. The outbreak, a Public Health Emergency of International Concern (PHEIC), poses a threat to countries worldwide, especially those with weak health systems and low levels of pandemic preparedness. It is of urgent importance that we move quickly to finance the development of the appropriate countermeasures for a disease that risks becoming endemic across the globe. Two critical issues are necessary to address: i) immediate financing for the development and scale-up of a diversified portfolio of vaccines, and ii) financing the manufacturing and procurement of vaccine for global distribution. To enhance our discussions we are working on a background paper which we will share along with an agenda at the earliest. Recognizing the short notice, we will provide remote connection details for those unable to travel for the meeting. A working lunch will also be provided. We hope that you will be able to participate in this important meeting. Kindly confi rm your participation to Ms. Gabrielle Williams, Health, Nutrition and Population Global Practice, World Bank (wbheal t hevents@wo rl dbank.org ). Please do not hesitate to reach out with any questions . NIH-001742 Looking forward to your posit ive response. Best regards, Feng Zhao NIH-001743 Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 16:16:33 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Potentia l Speaking Engagement: Winter 2021 From: Date: To: Subject: Please RSVP sor ry no. Too busy. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Andrew Turley Cb)(6) Date: Wed nesday, February 19, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [El ,...:__:...._ _ _:__.:....:..!=::=~~---Cc: Andrew (b) (6J> Turl ey (b)(6)> Subject: Potential Speaking Engagement: Winter 2021 .. Dear Dr Fauci I know th ings must be impossibly busy right now with the current coronavirus issues but w anted to touch base to see whether you may be interested in a speaking engagement next Spring as part of our (b)(6) A bit about me : I am a (b)(6)Air Force Major General and retired SESfrom the Department of Defense. (b)(6) is an associate professor emeritus from the School of Medicine and Healt h Sciences at the George Washington University . We are both longtime adm irers. _____ .. consists of people drawn from a wide variety of backgrounds, including doctors, lawyers and many from the senior tiers of the finance and corpo rate worlds up to and including former CEOs and other executives (and even a few retired senior government folks like me). It is an active, well-read and learned community with a keen interest in current events . As an example, we have a very active Foreign Policy Association chapter that always draws folks from across the spectrum of political and policy perspectives for interesting and well -info rmed discussions. (b)(6) NIH-001744 Ou (b)( speaker series consists of presentations on a vast array of subjects, from literature and art to current events and public policy issues. Typically held on Tuesdays nights from December t hrough April, these sessions consist of a presentation of an hour or so followed by Q&A and general discussion. We always draw standing room only crowds. Recent and upcoming speakers have included: (b)(6) The recent coronavirus outbreak has captured the interest of the nation and the world. Our folks would be extremely interested in how organizations such as NIH respond and address these incredible challenges. A presentation by you about your work on t hese issues, from your groundbreaking work on AIDS onward or any other topic of your choosing, would be absolutely the height of our season. We pay transportation, lodging, an honorarium, and could even arrange for a round of golf at one of our outstanding golf courses! (Of equal importance is that we can offer you a brief respite from the cold of winter.). There are direct flights from Washington DC to West Palm Beach. We have openings in January, February and March 2021. We wou ld be deeply appreciat ive of your favorable consideration. Please feel free to contact me if I can answer any questions F. ANDREWTURLEY (b)(6) CELL: HOM E: NIH-001745 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 14 :42:50 +0000 Greg Folkers (b)(6) FW: Clip of Or. Fauci on NPR Good interview on NPR. Possible for Director's Page. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Lindsey Beall Date: Wednesday, February 19, 2020 8:22 AM To: Deatrick, Elizabeth (NIH/NIA ID) [C] ---------=(b.,.. )(= >; Pekoe, Ken (NIH/NIAID) [El (b)( Conrad, Patricia (NIH/NIAID) [El (b)( ; Fauci, Anthony ":" (N ""'."' 1"."". H"':" /N-:-1""'."' A~ID-:)-:[E~l ====----~ (b""" )("=",>; Ooepel, Laurie (NIH/NIAID ) [El (b)(6); --------- Fo Iker s, Greg (NIH/NIAID) [El (b)( ; Hoffman, Hillary (NIH/NIAID) [El (b)(6); Oplinger, Anne (NIH/NIAID) [El (b)(6); Rancourt, Anne ":': (N"".".' l'."':' H/7N .'"."."' IA '."".' l':". D):--: [~E):-===:::::.:._:,__,:;:~ (b..,... H= ; Lavelle, Judith (NIH/NIAID) [El (b)( ; Leitman, Laura (NIH/NIAID ) [E) (b)(6)•>; Stover, Kathy (NIH/NIAID) [El (b)( •>; Routh, Jennifer (NIH/NIAID) [El (b)( >; NIAID OD AM ; Awwad, David (NIH/NIAID) [CJ (b)(6) Cc: Osvald, Maria ; Fabry, Cynthia (NIH/NIAID) [El (b)(6); Meyl in Correa ; Ma rcia Bache ; Megan Schartner Subject: Clip of Dr. Fauci on NPR -------- -------- Good morning, Below is a clip of Dr. Fa uci discussing corona virus on NPR's Morning Edition. This clip aired earlier this morning . NIH-001746 https://app.criticalment ion .com/a pp/#/clip/publ ic/ 1b0d a 123-0cd? -40 12-90a6b82d27c73 l 91 ?show sentiment=fa lse Thanks, Lindsey From: Critical Mention Date: Wednesday, February 19, 2020 8:18 AM To: Lindsey Beall Subject: Critical Ment ion: Megan Schartner has shared a Radio Ment ion w ith you e critical • You're always on it w ith Critical Mention . e e ment1on Megan Schartner has shared a Radio Mention with you! From Megan Schartner (mschartner@scgcorp .com) NIH-001747 No Program Name Available Radio Program Name No Program Name Available Source WLRNFM Market OMA: 16 Miami, FL Time Feb 19, 2020 8:07 AM EST Clip Length 07: 16.852 it's morning edition from n. p. r. news on david green in culver city califomia and a militant in washington d. c. good morning in china the death toll from the corona virus has hit two thousand world leaders in public health officials are trying to contain it but new infections keep showing up earl golden for example he was a passenger on the diamond princess that's the cruise ship where hundreds of people got the virus we took an aquatic clues to also alone what went wrong who knew we were going and the crew and beautiful omar here's how he ended up in omaha earl his wife jerry were quarantined on that ship for twelve days in a felt fine the whole time but then the gun on a flight back to the u. s. and earl started feeling sick or wind burke from japan to this day about two hours into the flight they woke up with a high fever after napping a little bit and the doctors on board confirmed the and then on the flight landed he tested positive for the coronavirus he's recovering now in a bio contain mean unit at the university of nebraska's medical center he's going to have to spend fourteen days there and isolation well you know working %hesitation %hesitation catering we've heard on a but one of the two days of the different doctors each day i NIH-001748 didn't have a clue but got a little cough still you can you might want to debate left me and i'm a little to keep but maybe also because of the jet lag in the travels and everything else on top of it no it doesn't feel any different than you know recuperating from a regular coal earl's wave jerry hasn't been diagnosed with the virus is she's being monitored in a different part of the hospital but their case is a good example of some things we know and some things we don't know about how this virus is spreading so we have called doctor anthony fauci he's director of the national institute of allergy and infectious diseases good morning sir good morning so earl coleman was fine all those days on the ship then he gets on a plane and he gets a fever what does that tell us about how this virus is spreading well the virus has the ability to bind it to certain cells in your body particularly in your long so you can get anything from miles a symptomatic illness to a cough and a fever to some people about oh about twenty percent of the people come to the attention of medical than physicians in health care providers can get serious pneumonias requiring intensive care it sounds like this individual is on the %hesitation mild side of the illness because as he said it doesn't feel much more than just a common cold and as a matter of fact corona viruses in general prior to this all one of the causes of the common cold okay so what does that tell us i mean bleary often looking at the cases we're looking at a rising death toll which is tragic we look much less at the people like early say you know my voice is raspy a had a fever had a cough the years a wide range of stuff symptoms with this virus did do do we know why some people seem to be doing okay and other people are getting hit really hard well whether a couple things about that for the first thing is that any any kind of viral infection or any pathogen infection there's always a wide range of responses in the sense almost like a bill shaped curve some people get no sim is at all and we do have a symptomatic corona virus infection with this particular episode and then there's the bulk of people who get some sort of symptoms and then a small percentage of people do really really very poorly now that relates to the ability of the body to handle the virus and the one thing we know when it's not unique to this virus is that the elderly those with underlying conditions like chronic heart disease lung disease diabetes obesity they tend to get more complications much more than for example and otherwise healthy individual and that's the reason why if you look at the death rate which is around two percent for this disease at this time it is disproportionately high are among the elderly and particularly those who have underlying conditions this is interesting question carlin is wave terry presumably they work together the entire time they were quarantined right and if he gets the virus she does not did she just get lucky do some people have some sort of immune undefended don't it's a combination that's a good question it's a combination of both there is no virus that has one hundred percent attack rate even the most of infectious of all viruses like measles doesn't get a hundred percent of of %hesitation vulnerable people but respiratory viruses particularly things like influenza or the corona virus the attack rate is burying percentage and it was if he was really likely that his wife i don't think she necessarily had any on the line immune protection though that's possible the maybe some cross reaction of immune protection with other %hesitation microbes that she came into contact with but in most likely is as you suggest the luck of the draw okay interesting NIH-001749 and they got to patching wondered if you could clear something up because we've been hearing reports about so called super spread ours these you who spread the virus to a very high a number of other people and it sounds like a scary thing but and i just under is this a real phenomenon there that there are people who give the virus to more people than most and why is that happening well it is certainly the phenomenon of the super spreading israel we story with sars back in two thousand two and two thousand in three and they're episodes already with this particular new corona virus and it's a combination of two things it's an individual whose either at a particular moment in time shedding a very large amount of virus which makes it much easier to infect a group of people who are around him but you also see it sometimes in the hospital setting when you have a number of health care providers taking care of someone and that person is shedding a lot of virus so the short answer to your question is there are super spread is and it's a real phenomenon okay okay what we would you say at this moment is the most important or the most pressing question about this virus that we don't have answers to yet well what we don't know for sure we know that there are people who are infected will without symptoms or very minimal symptoms they hardly notice they're infected well we don't know is the extent to which people who have no symptoms are spreading it so we do know that this can occur because we have anecdotal documented cases of people who do not have symptoms who actually have infected someone usually a family member but we don't know the extent to which this cars in the broad component of this outbreak doctor anthony fauci the director of the national institute of allergy and infectious diseases sir thanks for joining us it was a pleasure to be with you Cntical Me111ionallows users to SP,archglobal TV Radio. Onlire News & Social from the United States Canada. and Eur:ipe watch video, edit and share coverage rere1ve real-lime emai alerts. build reports, and analyze coverage through word clouds and graphs. ·Nant lO learn more about Crittcal Menton? Sign up ror a den,c ~ - NIH-001750 NIH-001751 From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 19 Feb 2020 13:03:08 +0000 To: bdoherty@mrns.org Cc: lbaden@nejm.org;Fauci, Anthony (N IH/NIAID) [E];Redfield, Robert R. (C0C/O D); Lane, Cliff (NIH/NIAI D) [E];Eisinger, Robert (NIH/NIA ID) [E] Subject: RE: New England Journal of Medicine Editoria l Attachment s: H. Cliffo rd Lane's ICMJE-2013 - For Coronavirus Editorial Fauci et al -.pdf Briana: Cliff Lane has separately sent his signe d CTA. I am attach ing his ICMJE Form. And so you should have all the forms for all 3 authors: Fauci, Lane, and Redfield. Please let me know if you have any questions. Best regards , Tony Anthony S. Fauci , MD Directo r Nat iona l Ins titute of Allergy and Infectious Disease s Bui lding 31, Room 7 A-03 31 Center Driv e, MSC 2520 Nat iona l Institutes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation . It sho uld not be used by anyone who is not the orig ina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its repre sentatives. ----- Original Message ----From: Br iana Doherty Date: Monday , Febrnary 10, 2020 11:11 AM To: Fauci , Anthony (NlH /NlAID) [E] (b)( > Cc: lbaden @nej m.org Subject: New England Jou rnal of Med icine Edito rial ------~~ Dea r Dr. Fauci , I am delighted that you have agreed to write a signed editorial to accompany the article on the initial estima tes of key transm ission parame ters associated with nCoV -2019 virus by Li et al. The genera l purpose of the Journ al's editorials is to provi de the reader with an authoritative interpretation or elaboration based on the substance of the article. Since thi s substance is usually not within the average reader's special com petence, such readers wi ll particularly benefit if the editorial avo ids techn ical jargon, exp lains the artic le's contribution to a field of knowledg e, and em phasizes, whene ver possible, its clinical implications. Th e editorial commentary shoul d not be concerned excl usively with the article in question but rather should use the artic le as a starting point for a more genera l di scussion . Because editorials invo lve interpretation and opinion, you and your potentia l coauthor must be free of significant relevant financia l associations (including equity interest, regular consultancies, or major research support) with a company , or wi th a competi ng company , that stands to gain from the use of a product discus sed in the editorial. Please contact me immediately if you are conside ring a coauthor , sol can ensure that your candidate meets our NIH-001756 criteria. Additional information about disclosure of financial and other associations appe ars below this letter. Please bear in mind that your editorial represents your (and any coauthor's) personal opi nion. The Journal does not include statements of grant or other support or acknowledgments with editorials. Journal policy dictates that we must have on file a signed Copyright Transfer and Authorship Agreement from each author before a manu script can be accepted. Therefore, the enclosed form sho uld be signed by all authors and faxed to (781) 207-6529. Your editor ial is due at the Journa l on Monday, February 17, at the very latest if the deadlin e imposed by our p1inting schedule is to be met. If the editorial is to include a figure, please submi t the figure at least one week before the due date for the editorial itself. *** Additional *** information about preparing and submitting your editorial is given below; please read it carefully. The editors must reserve the right to edit (or even reject) your editorial, but whether we use it or not, the Journal currently offers a modest stipend of $300 . Thanks again for agreeing to write this editorial for the Journal. l look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New Eng land Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http:// www.ne jm.org LENGTH OF YOUR EDITOR IAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approx imately 4500 characters) . Note that we spell out tiia l names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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NIH-001759 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:37:58 +0000 Jon LaPook RE:Coronavirus It means that you are an outstanding and committed journal ist . Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : CbH6J FAX: (301) 496-4409 (b)(6) E-mail: The informat ion in this e-mail and any of its attachment s is confidential and may contain sensitive informat io n. It should not be used by anyone who is not the original intend ed recipient. If you have received thi s e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon laPook -------=-:-= (b)(6) Date: Wednesday, February 19, 2020 7:36 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Coronavirus -------~~ --------- CbH6) Got it . What does it mean that I'm waking up th inking about coronavirus? :) Jonathan LaPook, M.D. Chief Medi cal Correspondent, CBSNews Professor of Med icine NIH-001760 NYU Langone Health Twitter @DrlaPook On Feb 19, 2020, at 7:33 AM, Fauci, Anthony (NIH/NIAID) [E] CbH > wrote: -------- Jon: Your hypothesis is certainly possible, but I think unlikely. In a NEJM paper for which I have just written an editorial, there were 400+ patients and none younger than 15 years old. I am certain that children from birth to 15 years were exposed to and primed by coronaviruses multiple times and so if 2nd infection enhancement were an important issue, we should have seen it in children and adolescents 15 years old and younger. Just a thought, but anything is possible. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: CbH6J FAX: (301) 496-4409 E-mail: CbH6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Jon LaPook-------="'"'="CbH6J Date: Wednesday, February 19, 2020 7:26 AM To: Fauci, Anthony (NIH/NIAID) [E] ----------=-c-~ CbH6) ---------NIH-001761 Subject: Coronavirus Good morning, Tony, I woke up thinking this: given the relative sparing of young people during the COVID-19 outbreak, could something similar to what happens with dengue be going on? Could a second coronavirus infection - albeit with a genetically different variant than the first - bring about worse disease than the first? And, since up to a third of the common cold is caused by a variant of coronavirus, could older people somehow have been primed by an earlier coronavirus infection? Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBSNews Professor of Medicine NYU Langone Health Twitter @DrlaPook NIH-001762 From: Date: Fauci, Anthony (NIH/NIAIO) [El Wed, 19 Feb 2020 03 :41:52 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Redfiel d, Robert R. (CDC/0D);Cetron, Marty (CDC/DDIO/NCEZID/DGMQ) Cc: Billet, Courtney (NIH/NIAID) [E] Subject: FW: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Folks: You should take a look at this video (see link). The person, who is a Japanese in fectious diseases specialist, is a b it inarticu late in the beginn ing o f the video, but he provides a vivid and disturbing description of the conditions on the Diamond Princess. Tony From: Larry Washburn< (b)(6)> Date: Tuesday, February 18, 2020 9:43 PM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'c= 6J> Cc: Hodes, Richard (NIH/NIA) [El (b)(6) Subject: Todays report from Dr Iwata From Kobe univ on Diamond Princess SHIP COVID-19 Dr. Fauci, I am living in Japan (b)(6) and this morning I saw t his video released by Dr. Kentaro Iwata a infectious disease contro l.specialist Please have somebody on your staff review this ASAP short description of Dr lwata's 1 day visit on the ship. He has experience with Ebola, Sars etc . He describes an alarming condition that you and CDC must be aware of . Japan has no CDCand they tend to be very bureaucratic. https ://www .you tu be .com/wa t ch?v=vt HYZkl u Kcl &featu re=youtu . be I apologize if you already have this information . Respectfu lly Larry Washburn ______ _, Living in Japan (b)(6) NIH-001765 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01 :32:37 +0000 Conrad, Patricia (NIH/NIAID) [E);NIAID OD AM RE: CROI COVID-19 Session; Tuesday March 10 lunch I am not that excited about doing this. They have CDCdoing the Epi, which is fun. They have Ralph Bar ie doing the virology, which I easily can do , and they have me talking about what NI A ID is doing, which is important, but boring from a lecture standpoint. Greg: What say you? From: Conrad , Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Tuesday, February 18, 2020 8:22 PM To: NIAID OD AM Subject: Fwd: CROI COVID-19 Session; Tuesday March 10 lunch Sent from my iPhone Begin forwarded message: From: Donna Jacobsen Date: February 18, 2020 at 8:18:06 PM EST To: "Fauci, Anthony (NIH/NIAID) [E)" 1 Cc: "Conrad, Patr icia (NIH/N IAID) [E)" I CbH6>i, "Elaine J. Abrams, MD ____ ..;__ __ ..,;_......; __ ..:..;...:...::::::::e (b ;:;)="' c6) ::;; ij-"-:::S:ha_r_o_n_H-:: il".".' Iie _r_P :-:-" hD . ~=======:.~= (b)(6)1>, "Hoxie, James" ============-~~:--:----:--:-:. CbH6)], "Benson, Connie" ! CbH6)]>, Kevin Bowen ------------ Subject: RE: CROI COVID- 19 Session; Tuesday M arch 10 lunch (resending with Patty's correct email address) Dear Dr Fauci: As I mentioned on the phone, we just today decided that we w ill have a special session on COVID-19 at CROI. It will be on Tuesday, March 10, dur ing the lunch break; the initial general structure will be a 10- to 15- minute overview of the epidemic (CDC), a 25-min talk by Ralph Sarac (UNC) about the viro logy of coronaviruses, and a 10- to 15-minute summary on what NIAID/NIH is doing and planning. We thought that this being one of the first large med ical conferences in infec t ious diseases this year, t hat it is important that we address COVID 19 at CROI. NIH-001768 We know that this is terribly last minute, but the CROI Chairs and Foundation are hoping you are free to give the NIAID/NIH update . CROI is in Boston, March 8 to 11. If you think you would be able to do this, we will send a more formal communication w ith details and wo rk with Patty on the specifics. Thank you so much Dr Fauci; we hope you will be ab le to join us. Best, Donna Donna M . Jacobsen Executive Director /President International Ant iviral (formerly AIDS) Society - USA 131 Steuart St, Ste 500 San Francisco, CA 94105 415 -544-9400 https ://www.iasusa .org ~ ACCMf About IAS-USA : Established in 1992, the IAS- USA is a not-for-profit , professiona l education organization. The mission of the IAS-USA is to improve the prevention, treatment, care , and quality of life for people with or at risk of HIV, hepatitis C virus, or other viral infections through high -quality, relevant, balanced, and needs-oriented education and information for practitioners who are actively involved in medical care. The organizat ion's educational activities are particularly intended to bridge clinical research and patient care . Confidentiality Notice : This e-mail and its attachments may contain privileged and confident ial informat ion intended solely fo r the use of the IAS-USA and the recipient(s) named above . If you are not the intended recipient. or the employee or agent responsible for de livering th is message to the intended recipients , you are hereby notified that any review , dissemination, distribution, printing, or copying of this e-mai l message and/or any attachments is strictly prohibited . If you have received this transmission in error , please notify the sender immediately and permanently de lete this e-ma il and any attachments. NIH-001769 From: Date: To: Subject: Autoimmunity, Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:28:47 +0000 Retzlaff, Jon RE:ACTION: Invit ation to Provide Opening Remarks at the NIH-AACR Cancer, and Immunology Conference on March 23rd (on the NIH campus) Not inte rested right now. Too busy. Have Hugh or someone else do this. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Retzlaff, Jon Date: Sunday, February 16, 2020 6:12 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C) ------~~ ~-========~-==Conrad, Patricia (NIH/NIAID) [E) (b) (6}> (b)(6)> ---------- (b)(6)>; Subject: ACTION: Invitation to Provide Opening Remarks at the NIH-AACRCancer, Autoimmunity, and Immunology Conference on March 23rd (on the NIH campus) Dear Dr. Fauci , It's pretty clear that you have been ridiculously busy over the past month+ serving as our nation's top infectious disease doctor! Thanks so much for yom leadership and dedicat ion, Dr. Fauci! I'm actuallyreaching out to you on a topic other than the coronavirus,as I am writing on behalf of the co-chairs for an important NIB-American Association for Cancer Research (AACR) conference (the NIH-AACR Cancer, Autoimmunity, and Immunology Conference) that will be taking place on March 23-24, 2020 , on the NIH campus (in the Masur Auditorium in the NIH Clinical Center). The co-chairs would like to invite you to be the opening speaker on Monday, March 23rd . Dr. Sharpless will be the open ing speake r on Tuesday, March 24 th . Please see the attached draft agenda. NIH-001770 Now in its third year , the Cancer, Autoimm unity, and Immunology Conference focuses on: 1) understanding the biology of immune-related adverse events which have occurred in cancer patients trea ted with immunotherapies and how that might inform the study of autoimmune disease , and 2) defining the potential for the study of autoimmune disease to lead to greater understanding of the treatment and management of immune-related adverse events during and following cancer therapies. The goal of this interdisciplinary conference is to bring together people who might not typically interact to promote cross-fertilization for the betterment of both research and clinical care, which is why there are four NIH !Cs very much involved in the Conference, including: NCI, NIAID, NIAMS, and NIDDK. Chairing this effort on behalf of the AACR is Julie R. Brahmer, MD, Johns Hopkins Un ivers ity. From the NIH, we have Elad Sharon , MD, MPH, NCI; Ravi Madan , MD, NCI ; Connie Sommers, PhD, NCI; Howard Young , PhD, NCI; Katarzyna Bourc ier , PhD, NCI; Marie Mancini , PhD, NIAMS; Annette Rothermel , PhD , NIAID; and Lisa Spain , PhD , NIDDK. I know the diverse audience, including patients , researchers , clinicians, industry , regulators, and others, would be thrilled by your presence. Of couTse, we also know that you have pa1ticipated in the previous two conference on this topic, which underscores why they would love to have you participate again! Plea se let us know at your earliest convenience if you are interes ted and able to participate in the conference on Monday, March 23rd. ff you have additiona l questions or concerns, you can contact me at jon .retz laff@aacr.org or (b)(6) Thanks again , Dr. Fauci , and I look forward to hearing from you ! Jon Jon Retzlaff, MBA, MPA CHIEF POLICY OFFICER VICE PRESIDENT, SCIENCE POLICY AND GOVERNM ENT AFFAIRS Office of Science Policy and Government Affairs AmericanAssociation for cancer Research AAG FlNDINGCURES TOGETI;ER ' American Association for Cancer Research 1401 H Street. NW. Suite 740 I Washin gton . DC 20005 202-898-6499 I Direct jo n.retzlaff@aac r.org I 267-765-1087 Fax I (b)( Cell www .AAC R.org 11c miam•+:Pili Please note that this e-mail and any files transm itted w ilh it may be privileged , confidentia l, and protected from d isclosure under applicable law. This information is intended only for the person or entity to which it is addressed and may contain confidential or privileged material. Any review, NIH-001771 retransmission, dissemination, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is prohibited. If you received this in error, please contact the sender and delete the material from any computer. NIH-001772 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 00:23:40 +0000 To: Subject: Eisinger, Robert (NIH/NIAID) [E] FW: New England Journal of Medicine - 20-02387 FYI. Just to keep an eye on this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases BuiIding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 (b)(6) E -mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any stat em ents mad e that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -------- -----Original Message----From: New England Journal of Medicine Date: Tuesday, February 18, 2020 10:41 AM To: Fauci, Anthony (N1H/N1AID)[E] _______ (b)(6);Lane, Cliff(NIH/NIAJD) [E] (b)( >; Redfield, Robert R. (CDC/OD) (b)( .,....,....,.. __,_.....,....__,__. Subject: New England Journal of Medicine - 20-02387 _ -------~~ Dear Dr. Fauci, Thank you for submitting your manuscript, "COYID-19: Navigating the Unchartered" to the New England Journal of Medicine. Your manuscript has been fo1warded to members of our editorial staff, wbo will make an initial evaluation and decide whether it merits further consideration. You will be notified of the decision as soon as possible. Your manu script TD is 20-02387. Please mention th e abov e manuscript ID in all future conespondence or when calling the of.fice for questions. If there are any change s in yow· street address or e-mail addre ss, plea se log in to ScholarOne Manuscript s at h tt:ps://mc0 5.manuscr ip tcentra l.com/nejm and edit your user infom1a tion as appropriat e. You may al so view the sta tus of your manuscript at any time by checking For Authors section of the site. We are undert aking evaluation o f y our manu script with the understanding tha t neither the substance of the article nor the figures or tables have been published or will be submitted for publication elsewhere during the period of review. Please provide the editors with copies of other manuscripts by you or your coauthors addressing similar or related research questions that are in preparation or under consideration at other journals. This does not apply to abstracts published in connection with sdentific meetings or to news reports based on presentations at such meetings. The Journal's policy is explained more fully at http://www.nejm.org/page/author-center/editorial-policies. NIH-001773 Please call us at 617-734-9800 if you have any questions. Sincerely, Eric J. Rubin , MD, PhD Editor- in-Ch ief New England Journal of Medicine IO Shattuck Street Boston, MA 02115 (617) 734 -9800 Fax: (617) 739 -9864 http: // www .ne jm.org NIH-001774 Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 23:57:32 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [El RE: draft response fo r NBC on line Subject: See my minor tweek Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------________ --------:a ~aa, From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 18, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: draft response for NBC on line (b)(6) ,. (b)(6J> Ok any edits? Pis advise Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001775 (b)(6) From: Routh, Jennifer (NIH/NIAID) (E] Date: Tuesday, February 18, 2020 2:47 PM To: Conrad, Patricia (NIH/NIA ID) (E) (b)(6J1 >; OCPLPressTeam <0 CPLPressTeam@ o d. ni h.gov> Cc: NIAID COGCORE; NIAID Media Inquiries Subject: draft response for NBC on line --------------------------~~ Reporter : Jacqueline Stenson Organization: NBC online Phone #(s): Subject: COVI0-19 ------------------- (b)(6) NBC on line asked, "What is NIAID's position on whether the SARS-CoV-2is transmiss ible in asymptomatic people?" I would propose that we send a response to Jacqueline attributed to ASF: Early case reports indicate in certain circumstances SARS-CoV-2is transmissible in asymptomatic people. We do not know the extent to which asymptomatic transmissionis impacting the outbreak. However, we know that people w ith symptoms are usuallythe main driver of outbreaks of other respiratory diseases. Jennifer Routh [E] News and Science W riting Branch Office of Communications and Government Rela tions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ( Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-001776 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 23:32:19 +0000 Dennis Golden Monica A Golden RE:Coronavirus To: Cc: Subjec t: Denny and Monica: Many thank s for your kind note. l hope that all is well wi th you. Warm regards , Tony Anthony S. Fauci , MD Dir ector National Institu te of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Ins titutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete il from your mai lbox or any other storage devices. The National Institu te of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Dennis Golden ------- (b ~)~(= > Date: Tuesday , February 18, 2020 4:39 PM To: Fauci, Anthony (NlH/NlAID) [E] Cc: Monica A Golden Subject: Coronavirus ------~~ ---------- Tony, Our thoug hts and prayers are with you as you profe ssionally address the horrid coro navirus transmission. We salute you for not "s uga rcoating" or trying to be "diplomatic " about the Diamond Princess Cruises ship quarantine process . As always, you proved yourself to be a courageous, honest and ethical man. A man who has always done the right thing s . We standwith you ! In Hoc Signo Vinces, Denny and Monica Golden NIH-001777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 22:06:38 +0000 To: Selgrade, Sara (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E);Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E);NIAID OCGRleg Subject: RE: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings Attachments: Draft_NIAIO FY2021 Statement for the Record_to ASF- with Fauci tracked edits.docx Here it is. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Selgrade, Sara (NIH/NIAID) (E) (b)(6)> Date: Tuesday, February 18, 2020 4:18 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=(b=)(=6) Cc: Billet, Courtney (NIH/N IAID) [E) (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E) (b)( >; NIAID OCGRleg Subject: Requesting your assistance: Draft NIAID Statement for Upcoming Appropriations Hearings --------Dr. Fauci: In preparation for the upcoming NIH budget hearings of the House and Senate Appropriations Subcommittees on Labor, HHS, Education, and Related Agencies, we have drafted the attached NIAJD statement for the record, highlighting the topics that you previously selected. NIH-001778 We have a finn 3-page limit for the statement. It has been reviewed by the Divisions and Drs. Harper, Eisinger, Lerner, and Marston, as well as Courtney Billet, Martin Johnson, Greg Folkers, and Laurie Doepel. NIH OLPA has asked to receive your statement by this Wednesday, Feb. 19th. Please let us know if you would like us to request additional ti1ne for your review, given competing priorities. Thank you for your help. Sara Sara Selgrade, Ph.D. Section Chief for Legislative Activities Legislative Affairs and Con-espondence Management Branch Office of Communications and Government Relations NIATD/NTH /DHHS Bldg. 31, Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclui m e,-: The i1!formation in this e -mail and any wrote : Dear Tony, (b) (4) With best regards, Rao On Mon, May 1, 2017 at 9:40 PM, Fauci, Anthony (NIH/ NIAID) [E] ------- (b)( 6) wrote : Rao: ao Wo.Ll: he.n.ate..aadJo (b) (4)'--- ~ e t'i'ega"'fi , Tony From: Venigalla B Rao [mailto:, Cb) (6)J Date: Thursday, April 27, 2017 8:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Arthos, James(NIH/NIAID) [E]; ----Subject: Request =(b=)( = 6) NIH-001787 = (b) (4) Dear Dr. Fauci, This is Venigalla Rao from The Catholic University of America, Washington , DC. I have communicated with you a couple of times in the past years for different reasons. Having been involved in administrative duties (miniscu le compared to yours ), I can only imagine the demands on your time . I make this request despite this trepidation and I hope that you understand . (b) (4) Thank you for consideration. With best regards, Rao Dr. Venigalla B. Rao Professor and Chairman Department of Biology The Catholic University of America 620 Michigan Ave., NE Washington, DC, 20064 http://faculty.cua.edu/rao/ Phone: (b) (6) NIH-001788 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 202014:12:48 +0000 SuzannePeskin RE:Visiting ! Suzanne: Thanks for the note. lam very, very sorry, but I do not think that we w ill be able to connect on Sunday. The White House and HHS have me going 24/7 including Saturday and Sunday with the coronavirus crisis. I have seen my witi (b) (6) for a total of about 45 minutes over the past l 0 days. Hopefully , we can do this at some other opportunity , but th is is a very bad time. I hope that you understand. Best regards , Tony Anthony S. Fauci , MD Director National Jnstitute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301)496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachments is confidential and may cont ain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Jnstitute of Allergy and Infectious Diseases (NfAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Suzanne Peskin -------~ (b~)-(= Date: Monday , February 17, 2020 9:56 PM To: Fauci , Anthony (NTH/NTAID) [E] ._ _____ Subject: Visiting ! ------~~= (b_H_ > Hi Tony, r hop e all is well with you and your family. r know you are busy these days witb the Coro novir us, bu t was wonderin g if you' re in town this weeke nd! (b)(6llives in DC and works for Mary land CASA as a legal fellow . J'm com ing in Friday even ing and was planning on taking her down memory lane. She has heard so much about (b)(6) that I would love to introduce you two. (b) (6) 'e are free most of Sunday if you 're in town. It's been way too long. Would love to see you. Let me know if that is at all possible. Love, Suzanne Sent from my iPad NIH-001789 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 13:17:03 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b) (4) for coronavirus Date: To: Subject: Attachments : (b)(4) Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Li,Qiuhong (b) (6) Date: Tuesday, February 18, 2020 8:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: (b)(4) for coronavirus ---------- ------~~ -------- (b)(6)> Dear Dr. Fauci, I'm writing to you to seek advice on potential collaborations with NIAID-funded facilit ies or other private sectors to Cb)(4) (b) (4) NIH-001790 (b) (4) Please feel free to contact me if you have any questions . Best regards, Qiuhong Qiuhong Li, Ph.D , Dept. of Ophthalmology University of Florida Gainesville FL 32610-0284 Phone Email: (b)(6) ---- (b)(6) NIH-00179 1 From: (b)(6) Date: To: Subject: Tue, 18 Feb 2020 07:00:32 -0500 Collins, Francis (NIH/OD) [E] Re: Funds for CoV Francis: (b) (5) Tony On Feb 18, 2020 , at 6:22 AM , Collins, Francis (NIH/OD) [E] (b) <6J >wrote: Hi Tony, Larry and I will have our regular meet ing with the Secretary today . (b) (5) --- I will see you th is afternoon for our regular catch up, unless other events in our intensely busy lives intervene . Francis NIH-001792 =(b~)( =5) From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:15:14 +0000 Bernice Mika Huang RE: Singapore Coronavirus Updates To: Subject: Bernice: Thank you for this important update of information. Best regards, Tony -----------------.~ From: Bernice Mika Huang Date: Tuesday, February 18, 2020 4:40 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Singapore Coronavirus Updates (b)(6) -------- (bH > Dear Dr. Anthony Fauci, I'm Bernice ------ (b) (6) . I had read your online discussion details on USA Today which says: "Another thing that we don't know is why, w ith a respiratory-borne illness, are there virtually no children getting infected . I mean, there are no cases of kids less than 15 years old . Does that mean for some strange reason they're not getting infected, or the illness is so mild in child ren that we're not notic ing it? It's very clear the median age is 56 or 59." I thought it would be crucial to share updates on Singapore's coronavirus situation for your reference, because you are the expert who could help analyze the cur rent situation . Till date, in Singapore >< 6>have two young child ren who are infected: ONE YEAROLD "Case 76 is a one-year-old Singaporean who was among the group evacuated from Wuhan on Feb 9. The toddler was without symptoms when he boarded the flight back to Singapore. He was put under quarantine upon landing in Singapore, and was confirmed to be infected with COVID-19 on Sunday afternoon . Advertisement He is currently warded in an isolation room at KK Women's and Children's Hospital, said MOH." Quoted from https://www .channe lnewsasia.com/news/singapore/cov id19coronav irus-singapore -update-feb- 17-12441176 SIX-MONTH OLD "COUPLE, BABYAND MAID INFECTEDThe 28-year-old mother - whose infection was announced on Tuesday - works at Yong Thai Hang, a health product shop that primarily serves Chinese touris t s. Her husband, a 45-year-old Singaporean tested positive on Wednesday at about 2pm, and is currently warded in an isolation room at the National Centre for Infectious Diseases (NCID). Both have no recent travel history to China. The couple's child, a six-month-old boy, tested positive at the same time and is currently warded in an isolation room at KK Women's and Children's Hospital. The family's domestic helper was one of the confirmed cases on Tuesday. MOH said in an update on Thursday that the child NIH-001793 was not in any infant care facility and was cared for at home, prior to being admitted to the hospital." Quot ed from http s://www .channe lnewsasia.com/new s/s ingapore/w uhan-virus-coronavirus-singapore-numbe r-cases- 12395928 Thanks,Best Regards& God Bless, BerniceHuang (b)(6) Best Regards, Bernice NIH-001794 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:12:55 +0000 Sheeley, Colin (NBCUniversal) RE: NBC News Inquiry I know that it is frustrating for you, but they still have not changed the official number , even though we know that it is certainly more than 44. Sorry . From: Sheeley, Colin (NBCUniversal) Date: Tuesday, February 18, 2020 12:26 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: RE:NBC News Inquiry Thank you Tony, We heard th is evening that there were 169 new confirmed cases aboard the cruise ship . Do you know if this changes the "officia l public" number at all? Thanks, Colin From: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Date: Monday, February 17, 2020 8:19 AM To: Sheeley, Colin (NBCUniversal) Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal) ; Santana, Cristian (NBCUniversal) ; Mitchell, Alexander (NBCUniversal) ; DiCasimirro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subject: [EXTERNAL)RE:NBC News Inquiry Colin: Thanks for the note. The number 44 is in flux. When I checked a couple of days ago, the "officia l public" number was 44. However, it was clear that there was likely more than that since the results of the tests were st ill coming back on some individuals. And so, it is a of 44 infected from the cruise ship, but it is un certain how many more than 44 are infected . I do not know where the Americans are staying Best, minimum Tony NIH-001795 From: Sheeley, Colin {NBCUniversal) Date: Monday, February 17, 2020 3:36 AM To: Fauci, Anthony (NIH/NIAID) [E] ------ ~= (b)(6)> Cc: Chirbas, Kurt (NBCUniversal) ; Varela, Jay (NBCUniversal ) ; Santana, Cristian (NBCUn iversa I) ; Mitchell , Alexander {NBCUniversal) ; DiCasimir ro, Gemma (NBCUniversal) ; Studley, Joe (NBCUniversal) ; Metsch, Abigail (NBCUniversal) Subjec t : NBC News Inquiry Hi there, I'm reaching out on behalf of NBC National News -would you be able to confirm that 44 Americans aboard t he Diamond Princess cruises ship have tested positive for coronavirus? Also, would you be able to say where the Americans are staying as they are being treated for the virus? Please REPLYALL with your response, or give us a call at (212) 664-5222. Thank you, Colin NIH-001796 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 11:08:19 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNNi Interview Request: Anthony Fauci Let us discuss. From: Hynds, Joanna (NE) Date: Tuesday, February 18, 2020 5:49 AM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Cc: Pfeifer, Hazel ; Roobeek, Rosanne ; Avramova, Nina (NE) Subject: CNNi Interview Request: Anthony Fauci Dear Mr Fauci, I hope this finds you well. I'm writing to you from CNN International to see if you are available to join Becky Anderson on her prime time flagship show 'Connect the World' for a live interv iew on today to discuss the coronavirus. The show airs live between 10amET- 12pmET- do you have any availability dur ing these hours to come to a convenient bureau? We really loved having you on the show last Sunday! As the director of the National institute of Allergy and Infectious Diseases your insight is always great fo r our global audience. Migh t it be possible to arrange something? Background on CNN • CNN Int ernational reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN Int ernational is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN.com had 162 million unique readers globa lly per month and 114 million mobile reade rs a month, leading the BBC, Yahoo and New York Times . Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + Cb)(6) ( cell) joanna .hynds@turner .com NIH-001797 amthere go Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-001798 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 10:44:58 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Confirmation from CNN's New Day OK. Thanks. (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Tuesday, February 18, 2020 5:42 AM --------- To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: Confirmation from CNN's New Day Firm hit for this morning in med arts studio at 715 am Be in studio at 7 am Sent from my iPhone Begin forwarded message: From: "Steinfe ld, Alix" Date: February 18, 2020 at 5:13:08 AM EST To: "Figliola, Mike" , Jonathan Bennett (b)(6)> Cc: "Conrad, Patr ici... a..:, (_ N_IH..:. /_N_IA_I_D.:.. ) .:.. [E..:. )'.'..!==~~':'."""'-:--:--- (b-:) __, (6)>, "Daniels, Ronne! (b)(6) "Ryland, Ken (NIH/OD/ORS) [E)" (NIH/OD/ORS) [C]" ======= (b~)(~6)~>, "Jackson Farrar, Joy (NIH/OD/ORS) [El" (b)(6) Subject: RE: Confirmation from CNN's New Day Good Morning We have OR. ANTHONY FAUCI on New Day Hit Time; 715aEST IFB: 212.275.9225 PL: 212.275.9325 CONTROL: 212-275-9053 PO: 660980 Thanks Alix From: Figliola, Mike Date: Tuesday, February 18, 2020 5:12 AM To: Jonathan Bennett ----------- (b)(6) Steinfeld, Alix NIH-001799 Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) ; Daniels, Ronnel (NI H/0 D/0 RS) [ C] _:..___;_ ___;:....:.....::__::s: (b= )( .-.:: 6)~> ;- R -y'."" la-nd~,-K-en- ('."" N-1H/0 D/0 RS) [E] =======~ (b)(6)>; Jackson Farrar, Joy (NIH/OD/ORS) (b~)(~6) [E] Subject: RE: Confirmat ion from CNN's New Day Importance : High Add ing Alix who has that info Mike Fi g liol a Editorial Producer CNN's New Day (b)(6) mike .figl iola@turner .com CONF IDENT IALITY NOT ICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confidential informa tion that is legally privileged. If you are not the intended recipient , or a person responsible for de livering it to the intended recipient , you are hereby notified that any disclosure , co pying , distr ibution or use of any of the information contained in or attached to this message is STRIC TLY PROH IBITED. If you have received this transmissio n in error , please immediately notify us by reply e-mail at mike.fig liola@turner .com or by telephone at {917) 670 -9410, and destroy the origina l transmission and its attachments without reading them or savi ng them to disk. Thank yo u. ----------- From: Jonatha n Bennett 5 ent: Tuesday, February 18, 2020 5 :05 AM (b)(6) To: Figlio la, Mike Cc: Conrad, Patricia (NIH/NIAID) [El (NIH/ OD/0 RS) [ C] _.;...___; __ =======- CbH6>> ; Daniels, Ronnel :...;...;~= (b ~ ):::c (6) ~;-:R:-y :la-nd-:-,-:-: K-en- (:-:N'."."' I H/0D/0 RS) [E] (b)(6); Jackson Farrar, Joy (NIH/OD/ORS) [E] (b ~~;,;, (6) ~> Subject: Re: Confirma t ion fro m CNN's New Day Mike, Received and noted . What are the contro l room and and IFB numbers? Jonathan On Tue, Feb 18, 2020, 3:14 AM Figliola , Mike wrote : Hi eve ryone , NIH-001800 This is Mike with CNN's New Day. Hope you are well. This is to confirm Dr. Fauci will be a guest today, Tuesday 02 .18 .20 at around 7am EST to discuss: Latest on Americans who tested positive after evacuation from cruise ship; What we know about how coronavirus spreads https:// www.cbsnews.com / news/ transcript-dranthony-fauci-on-face-the-nat ion-februa ry-16-2020 / You will be solo at 7am ESTfor the segments. Alisyn Camerota and Jim Sciutto, in for John Berman, will both be conduct ing today's interview. Please arrive at the studio no later than 6:50am EST. Here is your studio confirmation: STUDIO INFO 2013424 THIS INTERVIEW WILL B E FROM their NIH MED ARTS STUDIO with a direct IFB connection Control Room numbers are 301-827 -8478 and 8479 Encompass Booking and Circuit Number : Booking : 1-800-243-1995 Circuit: 36TBGS104492 Our IFB: 301-496-1811 (we prefer to call into the station's IFB) Video : 1080i - the audio is embedded . Please confi rm you have received this and are all set to go ! Best, M Mike Figliola Editorial Producer CNN's New Day NIH-001801 (b)(6) mike.fiqlio la@turner .com CONFIDENTIALITY NOTICE: This e-mail transmission. and any documents. files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIBITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk. Thank you. NIH-001802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:08:59 +0000 Holland, Steven (NIH/NIAID) [E] RE: New Coronavirus Draft Messaging To: Subject: Short and sweet. Looks fine. Thanks. ________ _, , (b)(6) From: Holland, Steven (NIH/NIAID) [E] Se nt: Monday, February 17, 2020 10:05 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: FW: New Coronavirus Draft Messaging Tony , When you get a moment could I get your take on th is most recent iteration . Apolog ies for the intrusions. Thanks Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 301-402-7684 voice (b)(6) fax (b)( email Assistant lab: Eva Portillo (b)( email ___ Cb _)_(6) _ voice --- Assistant to SD: Beth Schmidt (b)(6) (b)(6) From: "Bailin, Heike (NIH/OD/ORS) [E]" Date: Monday, February 17, 2020 at 10:01 PM To: "Moss, Bradley (N IH/OD/ORS) [E]" ---------.. Cc: "Gottesman, Michae l (NIH/OD) [E]" (b)(6)> (b=)(=6) CbH6) 1 , Steven Holland "Schmitt, James (NIH/OD/ORS) IE]" ~=======~~CbH6J, --------~~ (b)(6) "Johnson, A lfred (NIH/OD) [E] " ---------- "Pa Imo re, Tara (NIH/CC/OD) [E]" CbH6)>," McGowan, NIH-001803 Colleen Cb)( (NIH/OD/ORS) [El" CbH6) , "Cullen, William (NIH/OD/ORS) [El" CbH6)>, "Newcomer, Derek (NIH/OD/ORS) [E]" CbH6)>, "Tosten, Timothy (NIH/OD/ORS) [E]" ========~~ =======~ (b);;(-;; 6)~ Subject: Re: New Coronavirus Draft Messaging Brad- thank you . I liked much of what you did . And thanks to all who've commented and edited . Your points are well taken. For the sake of clarity and effectively steering fo lks to OMS for the proposed ICP measures I favor focusing the message even more. Pease find attached OMS ed its: NIH-001804 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 03:05:47 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: COVID 19 Diamond Princess Patients Possible Transmission by Fomites SARSTransm ission Fomites Temperature and Humidity Variables.pdf Please have someone respond From: Angela Moore (b)(6);, Date: Monday, February 17, 2020 10:04 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ (b)( > Subject: COVID 19 Diamond Princess Patients Possible Transmission by Fomites I am a dermatologist but also a clinical researcher and scientist. I was reading all of the news regarding concerns and questions on how the fellow patients are being infected . A few questions arose, based on the NIH data on SARSCoronavirus , that has been much more stud ied, and most likely less viru lent than the current COVID 19, wh ich supposedly has HIV traits as well as t raits to increase transmission. I have wondered if COVID-19 is like Legionella, and possibly transmitted in the airborne water droplets in the air conditioning units of the Diamond Princess ship. Even with the SARSCoronavirus, it was shown to be infective on fomites for up to 28 days unless 40 degrees Celsius and 80% humidity, when it was then inactivat ed in a few hours (see the attached article). I am wonder ing if the trays of food, after being passed to passengers on the ships, were then washed in suboptimal conditions (NOT at 40 degrees Celsium for several hours at 80% hum idity) I AM concerned , that based on the reinfection of those in Wuhan, China, after they returned home, on whether 14 days of quarantine is enough, based on the modeling and studies on the SARSCoronavirus, and whether 28 days of quarantine may actually be needed. With the HIV virus component of COVID 19, one must also wonder if the T cells are being infected and passing the infection along with in an infected pat ient . In the U.S., we may need to beware of blood trans fusions from anyone infected, even asymptomatically, w ith COVID 19. I am sure that you have teams of clinicians and scientists working on this, and I don't know if any of the original scientis ts working on the SARSmodels are still around at Chapel Hill to perform these related studies and modeling . Angela Moore Angela Yen Moore, MD Arlington Center for Dermatology Arlington Research Center NIH-001805 711 East Lamar Blvd., Suite 200 Arlington , Texas 76011 phone 817-795 -7546 fax 817-226-7546 NIH-001806 From: Date: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 18 Feb 2020 02:48: 13 +0000 To: bdohe rty@mrns.org Cc: lbaden@nejm. or g;Redfiel d, Robert R. (CDC/OD); (b)(6) ;Eisinger, Robert (NIH/ NIAID) [E];Greg Fol kers (b)(6)·Conrad, Pat ri cia (NIH/ NIAID) [El Subject: RE: New England Journal of M edicin e Edito ria l Attachment s: NEJM Edito ria l - Fauc i et al - FINAL - 02-1 8-2020.docx Briana and Lindsey : As promised, lam attaching the invited Editorial related to the COYID-19 manuscript that we had discussed. Should l also submit it through the NEJM online website or will you talce care of this? We will send in the COi and authorship forms in the next day or 2. Please let me know if you have any questions. Thank you. Best regards, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious D iseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nat iona l Institutes of Health Bethe sda, M D 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mai l (b) (6) The informa tion in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the origina l intended recip ient. lf you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institu te of Allergy and lnfectious Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of ihe NIAID by one of its representatives. -----Orig inal Message----From: B riana Doherty Date: Monday, February 10, 2020 11: I I AM To: Fauci, Anthony (NIH/NTAlD) [El (b)( 6) > Cc: lbaden@nej m.org Subject: New England Jou rnal of Medicine Editorial ------~~ Dear Dr. Fauci, I am delighted t:hat you have agreed to write a signed editorial to accompany the article on the initial estimates of key transmission parameters associated with nCoV-2019 virus by Li et al. The general purpose of the Journal's editorials is to provide the reader with an authoritati ve interpretat ion or elaboration based on the substance of the article. Since this substance is usually not within the average reader's special competence, such readers will particularly benefit if the editorial avoids technical jargon , explains the article's contribu tion to a field of knowledg e, and emphasizes , whenever possibl e, its clinical implications. The editorial commentary should not be concerned exclusively with the article in question but rather should use the article as a starting point for a more genera l discussion. Because editorials involve interpretation and opinion, you and your potential coauthor must be free of significant NIH-001807 relevant financial associations (including equity interest, regular consultancies , or major research support) with a company, or with a competing company, that stands to gain from the use of a product discussed in the editorial. Please contact me immediate ly if you are considering a coauthor , so I can ensure that your candidate meets our criteria. 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The editors must reserve the right to edit (or even reject) your editorial , but whether we use it or not, the Journal currently offers a modest stipend of$300. Thanks agaw for agreeing to write this editorial for the Journal. I look forward to receiving it. Sincerely yours, Lindsey R. Baden, M.D. Deputy Editor New England Journal of Med icine IOShattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739 -9864 http ://www .nejm.org LENGTH OF YOUR EDITORIAL NEJM editorials should not exceed two printed pages. This means that your word count before editing should not exceed 750 words (approximately 4500 characters). Note that we spell out trial names and most other abbreviations for our readers, and we include trial registration numbers for any clinical trials mentioned; these will lengthen your editorial if you have not included them. 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Please e-mail your completed disclosure form to editorial @nejm.org. ln the event of publication, each author's submitted disclos ure form will be posted on the Web (with any dollar amounts redacted) . COPYRIGHT TRANSFER Each author must complete a copyright transfer agreement form. Please sign it and fax it back to 781-207-6529 as soon as possib le. TO SUBMIT YOUR EDITORIAL *** It is important that you follow the instructions below to ensure that your article enters the con-eel.queue. *** When you are ready to subm it your manuscript, please log in to the New England Journal of Medicin e - Manuscript Centra l site (http ://mc05.manuscriptcen tral.com/nejm). Your case-sensitive USER ID is afauci@niaid.nih.gov. For security purposes, your password is not listed in this message. If you are unsure of your password , please visit https://mc05 .manuscr iptcentral.com/nejm and enter your e-mail address in the "Forgot Your Password ?" field. Once you are logged in, the Main Menu will be displa yed. Please click on the Author Center, where you will find the manuscript listed under "Invited Manuscripts ." You can click on the "Continue Submission" button to begin submitting your article. NIH-001809 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:48 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros To: Subject: FYI From: John Lauerman (BLOOMBERG/ NEWSROOM:) Se nt: Monday, February 17, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [E]------ -= (b-c)(c= 6) Subject: Comments on Tedros BTW, I just saw t h at you tr ie d me ear lie r a n d I d idn ' t respond . I was in Geneva and evidently didn ' t have service . Hope we can connect t hi s t im e . Bes t number i s my desk , +44 2035 2 5 1 028 . Thanks aga in , JL From: John Laue rman (BLOOMBERG/NEWSROOM : ) At : 02/17/2 0 1 4 : 37 : 11 To: AFAUCI @N I AI D. NIH . GOV Sub j ect : Comments Hi Dr . Fauci on Tedros : I ' m work in g on a story about WHO DG Tedros a nd t h e work that he ' s doing to contain the coronavir u s epidemic . I ' m planning on disc ussing a number of themes , incl uding that respo nding t o outbreaks has become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of how important it is t hat countries be as ope n as poss ible about enco u rage that and participation d isease outbreaks , and t h at i t ' s t he DG' s job and mov e countries toward gr eater transparency in battling outbreaks . Would you ca r e to to comment on t he job t hat Tedros is doi ng in t he se areas? Ple ase giv e me a call at + 44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , John Lau er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Vrctona Street London UK -------~= te + l4 ,r) 20 2 12 •t:)11 http ://www .bloombe rg .com http://www .bloombe rg .com /prog nos is --------- (b)(6) NIH-0018 10 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:09:18 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Comment s on Tedros Please t ry to set up a call with John Lauerman From: John Lauerman (BLOOMBERG/ NEWSROOM:) Se nt: Monday, February 17, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c= 6) Subject: Comments on Tedros Hi Dr . Fauc i: I ' m work ing on a s t ory about WHO DG Tedros a nd t h e work that he ' s doin g to contain the co r onavirus epide mic . I ' m p l a nning on d i scuss in g a number of t h emes , in c l ud in g t h at respo n ding t o ou t breaks h as become t he mos t v i sib le job of t he DG in the past couple of decades . I ' d also like to explore the issue of h ow im porta n t i t is t h at coun t ries be as o p en as poss ible abo u t d isease ou tb reaks , a n d t h a t i t ' s t he DG' s job t o enco u rage that and move co u ntries toward greater transparency and participation in battlin g outbreaks . Would yo u ca r e to comme n t o n t he job t h at Te dros is do ing in t he se areas? Pl ease giv e me a call at +44 2035 251028 or let me know when and at what number to call you . Thanks and re ga rds , J ohn La u er man , Bloomberg News John Lauerman, Bloomberg News 3 Queen Victoria Street , London , UK tel. +44 (0) 2035 251028 cell http :// www .bloomberq.com http://www .bloomberg .com /prognos is -------~= ------------ (b)(6) NIH-001811 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 18 Feb 2020 02:02:35 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b) (5) Cristina: (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-0018 12 From: (b)(6) Date: To: Subject: Mon, 17 Feb 2020 20:56:50 -0500 Collins, Francis(NIH/OD) [E] Re: (b) (5 for SARS -CoV-2 ---------- (b) (5) On Feb 17, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6)>wro t e: Hi Tony, (b) (5) Francis NIH-0018 13 From: Fauci,Anthony (NIH/NIAID) [E) Tue, 18 Feb 2020 00:20:01 +0000 Townsend, Frances RE:This ongoing 2019 novel coronavirus, or COVID-19,outbreak has a number ... Date: To: Subject: Fran: Thanks for the note. You certainly have covered a lot of ground with your questions. you tomorrow. Best rega rds, Tony I look forward to seeing Anthony S. Fauci , MD Director National Institu te of Allergy and Iofectious Diseases Building 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethesda, MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sen der and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----from : Townsend, Frances Date: Monday, February 17, 2020 6:55 PM To: (b)(6) ; Shuy, Bryan (OS/ASPR/IO) Fa uci, Anthony (NlH/NIAID) [E) Cb)(6) Conrad , Patricia (NJWNIAlD)[E] (b)(6) (b)(6) Cc: Hanson, E lizabet h Subject: This ongoing 2019 no ve l coronavirus , or COVID -19 , outbreak has a number ... All: Below is an outline of questions for tomorrow at CFR . Sorry to get this to you late but it seems the news changes everyday. As you will see I focus mostly on coro navirus as 1 suspect that's where the interest will be but get to bio weapons toward the end. l am happy to take additional questions or suggestio ns. These sess ions go quickly and we ha ve time for Q and A so I doubt I will get through it all but wanted you all to have something to look at. Thanks again for doing this tomorrow. Best Fran NIH-0018 14 This ongoing 2019 novel coronavirus, or COVID-19 , outbreak has a number of historic firsts. It's the largest quarantine in world history with China locking down over 60 million people. It's the first mass repatriation of Ame1ican citizens into a quarantine , climbing over 1,000. Let's start with some quick basics: what is coronavirus? How contagious? What is the morbidity rate? How does it compare to SARs and MERs? More/less infectious? Lethal? Just to put this in perspective every year here in the US we deal with the flu. How many Americans on average die each year from the flu? But as I mentioned corona virus has resulted in a number of historic firsts , talk about what you expect could be our scientific firsts and what roadblocks do those scientific firsts confront? Over the years, global economic interdependence has grown in nearly every industrial sector, including health care. But that means our health care is also globally interdependent on other systems less equipped, less transparent and perhaps less responsible global actors . China closed the wet market where the coronavirus outbreak began on 1/l , gene sequenced the virus on l/9 so they could develop a diagnostic test but did not share the gene sequence with the global hea lth community until 1/ 12. How transparent and quick was the Chinese response? What should the have done that they failed to do? What were the consequences? China now claims more than 70K infected and almost 1800 deaths from the virus. But Jt has been widely reported that the Chinese have underreported both numbers. what are Countries international obligations to report accurately? To whom? How do you know the numbers are accurate? How does the cwTent outbreak impact the domestic medical supply chain? What steps could or should we consider to enhance supply chain resilience? What do the numbers suggest to you about what to expect regionally and worldwide? Have numbers peaked? Will they continue to 1ise? With the cruise ship there re now a total of 15 Americans infected. Do you expect additional cases? What scale? How prepared are we nationally? Locally? Looking back over the roughly past decade , emerging infectious diseases played a recurring ominous theme . Be it from HlNl, to ebo la, then Zika, and now the 2019 novel coronavirus, the threat is clearly not dissipating. When it comes to non-disease natural disasters , the Stafford Act provides a Disaster Relief Fund to enable immediate response. By comparison , there is a small Infectious Diseases Rapid Response Reserve Fund. Do we need a more Stafford Act-like mechanism to enable quicker response and research to these new threats? What other actions can we take to better prepare ? While often we see folks painting emerging infectious diseases and biodefense into separate categories , the truth is that there is significant crossove r in terms of preparedness and research. Understanding that this is a sensitive topic, could you talk about how we should approach these risks in a comprehensive manner that can achieve public health and national security objectives concurrent ly? I'd like to use this to transition to the topic of bio weapons which is what we originally planned to talk about. The landscape here has also transfom1ed. When BioShield was written and the Strategic National Stockpile established we worried about State actors deploy ing banned weapons like small pox; plague and hemorrhag ic fever. And you NIH-001815 still must prepare against those things as well as new and emerging threats like the toxins we have seen deployed by Russia and North Korea in more targeted assassinations. How do you stay ahead of these threats? Do we have the resources and surveillance that we need to stay ahead of the threat? And ensure the necessary vaccines and therapeutics? The ebola outbreak may be an instructive example , it seems to be coming under some control despite the precarious security situation in the Democratic Republic of Congo. But the ongo ing 2018 outbreak was the second largest in history following the 2013-2016 West African outbreak. As a result of these outbreaks, the United States government has pioneered new FDA-approved diagnostics and vaccines , with promising therapeutics seemingly around the approval comer too. What lessons can we draw from the ebola outbreaks? How do you work with and incentivize industry to develop what you need in the event of a catastrophic bio attack? And How do you make the best possible decisions about the stockpile? I always worried that because we are global leaders if there was a bio attack or outbreak anywhere in the world, others would look to us and to our stockpile for the answer. Are our global allies doing enough to prepare against these tbreats--whether they be manmade or natural? Are they maintaining adequate stockpi les of medical countermeasures and research bases--and should they be? Lastly (if we have time) ....the FBI recently arrested a Harvard scientist for accepting undisclosed grant money from China for scientific research. It bas now been reported that there are similar investigations at a number of US universities including Yale and MIT to name two and that the grant monies are in the billions. What are foreign governments looking for? Why in the US? Clearly a national security risk, is it a bio weapons concern? DISCLAIMER: This e-mail message and any attachments are intended solely for the use of the person(s) named in the message header to whom the email is addressed and may contain information that is confidential or legally privileged. rfyou are not the intended recipient , you are hereby notified that any dissemination , distribution, copying , or other use of this message or its attachments is strictly prohibited . Jf you have received this message in error , please notify the sender immediately and pennanently delete this e-mail message and any attachments (and any copies or printouts of the same). NIH-001816 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 20:29:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [El FW: COVID-1 letter to NIAID-ICIS.pdf Please res pond to th e m. Tha n ks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-m ail and any of its attachments is confidential and may contain sensitive info rmation . It should not be used by anyone who is not the o riginal intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fitzgerald, Kate Se nt: Monday, February 17, 2020 1:52 PM To: Fauci, Anthony {NIH/NIAID) [El Cc: Eleanor Fish Subject: COVI0-1 --------:a =a Dear Dr. Fauci, On behalf of the International Cytokine and Interferon Society, p lease find attached a letter from us as clinic ians and scient ists committed to deve loping and implementing therapeutic interventions targeted against global viral infection outbreaks. We propose that high priority be given to evaluating the therapeutic antiviral activities ofIFN -as/bc(clinically appro ved formulation s) against COVID - 19 which poses a potent ial threat to globa l health. Further informat ion is deta iled in the attached. Tbe ICJS would be happy to provide the scientific and clinical expe1tise for this program and welcome further discussion. In particular Dr. Eleanor Fish copied above has the track record and expertise in this area. Sincerely , Kate A. Fitzgerald IProfessor of Me dicine President I International Cytokine and Interfero n Society (ICIS) NIH-0018 17 www.cytokinesociety.org Join us @ Cytokines 2020 iCIS NIH-001818 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 17 Feb 2020 20:22:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Happenings Radio Q+A ... Date: To: Subject: Let us discuss. She called me up today and I told her to send me an e-mail since I was on a cal l. For discussion. (b) (5) Anthony S. Fauci, MD Director National Institu te of Allergy and Iofecrious Diseases Building 31, Room 7 A-03 31 Cen ter Driv e. MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) Tbe informa tion in tbis e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ----- Original Message ----From: cassidy @ happeningsmag.com Date: Monda y, Febrnary l 7, 2020 3: 15 PM To: Fauci, Anthony (NlH/NlAID) [E]_____ ""°' (b""" )(~6) > Subject: Happenings Radio Q+A ... Hi there, This is Cassidy G-D from Happenings Magazine & Radio in Kenosha , Wl- we ever so briefly spoke on the phone earlier today. l was reaching out with the hope of getting you on our radio program for a 20-30 min ute Q+A in which we would talk abou t the Coronavirus and more specifically the impact it is having on the Diamond Princ ess Cruise ship along with anything you would like to talk about regarding infectious diseases and or your position as director of the National Institu te of Allergy and Infectious Diseases . Please let me know if you ha.ve any interest in being on the air with us a.nd I wou ld be happy to provide further details. You ca n also get ahold ofme by our office phone at 262-564 -8800 . Ho pe you are well and I look forward to hearing back from you, Cassidy G-D NIH-0018 19 From: Date: To: Cc: (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 19:50:25 +0000 Cassetti, Cr istina (NIH/NIAID) [E] Erbeldi ng, Emily (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad , Patricia BMGF Cristina: I just spoke with Chris Carp and Trevor Mundel of the BMGF and they want to try and coordinate some of the things that they and we are doing regarding COVID-19. I told them to give you a call to set up a teleconference to discuss respective R & D agendas of NIAID and BMGF. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail ( Cb ) C6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-001822 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 17 Feb 2020 18:58:46 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Info from China Please have someone respond to this person. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Cen ter Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informatio n in this e-ma il and any of its attachmen ts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the orig inal intended recipie nt. lf you have received this e-mai l in eITor please inform the sen der and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jodie Dillman --------~ (b ~)~(6) => Date: Monday , February 17, 2020 12:42 PM To: Fauci, Anthony (NlH/NlAID) [E] Subject: Info from China ------~~ (b)(6) > Dear Dr. Fauci, lt is with trepidation that I reach out to you with information that has been shared with me regarding the real status of the Coronavirus in China. My information comes to me from a (b) (6) who has correspondence from a nurse in Harbin , Ch ina. Cb _~_(6) _. is here on an H l V visa, employed for the past seve ral yea rs at the international studen t program. _____________________________ ____ _ T have no reason to doubt the authent icity of the correspondence that she shared with me. This corresponde nce shows a lung X -ray, a glass containe r of bloody fluid removed from an infected lung, and a map of Harbin , China dep icting many areas of the coronaviru s outb reaks. The written correspondence reveals that the numbers bein g release d of confirmed deaths is drastical ly low due to the spread be ing too fast to test. Deaths in hospital hallway s and of medical staff is not being shared in order to preve nt pan ic. Protec tive gear is unavai lab le and the nurse w 1iting the correspon dence is fearfu l for her life . She states that there are five levels of screenings (tests?) before a person is reported as testing positive or o f being infected with the virus . If someone dies before being confirmed , these suspected deaths are covered up and not report ed. Report ed numbers, even of conftnned cases are gross ly undercounted . l figure you and our government realize the infonnation and numbers coming out of China are highly inaccurate, but this correspon dence on (b) (6) confirms it. I felt it was only ethical and moral to report this, despite Cb _)_(6) _, plea that the two people involved in the correspo ndence fear governmental retribution if it was discovered that they discussed or pas sed on this confidential information . ____ 1 report this and swear it to be true and confidential. l am tnisting it will help in some way and 11otjust stir panic. NIH-001823 Jolonda Dillman (b)(6) Sent from my iPhone NIH-001824 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202018:51:17 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementation of influenza surveillance system for COVID-19 To: Subject: outbreak. FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Se nt: Monday, February 17, 2020 1:19 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: Re: Al supplementat ion of influenza surveillance system for COVID-19 outbreak. -------::-::-=, -------- ps - feel free to contact me at this address, or my personal email address, that is (b) (6). again, I have no dog in this fight aside from wanting to avoid a large scale pandemic worldwide. And I'm sincerely hoping that we throw the rulebook out - and develop a new one - to deal wi t h this the same way we did when we dealt with the 1918-1919 pandemic. On Mon, Feb 17, 2020 at 10:09 AM Ed Peshko wrote: Dr. Fauci, Like you, I've been watching the COVID-19 out break with great alarm . Given the current data, I'm almost positive at this point that it will hit the US hard at some point and as a student of history that terrifies me. NIH-001825 So I'm hoping that your department has contacted the Bill and Melinda Gates foundation and see if you could make the following idea national or international. It is a supplemental health system based on Al and mobile technology and consists oftwo planks: First: - train an Al to be able to detect COVID-19 by measurements that can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart-phone application that does the following : - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone. - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID-19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now th is all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed literature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope this is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distributed to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hoping that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire-suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious . I just think that in this case it is prudent for us to be safe rather than sorry. Thanks much, NIH-001826 ~ NIH-001827 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202018:47:09 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Al supplementat ion of influenza surve illance system for COVID-19 outbreak. Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Ed Peshko Se nt: Monday, February 17, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Al supplement ation of influenza surveillance system for COVID-19 outbreak . -------=-:--:= --------- Dr . Fauci, Like you , I've been watc hi ng the COVID-19 outbreak with great alarm . Given the curre nt data, I'm almost pos itive at th is point that it will hit the US hard at some point and as a st udent of history that ter rifies me. So I'm hop ing that your department has contacted the Bill and Melinda Gates foundation and see if you co uld make the fo llowing idea national or international. It is a supp lemental hea lth system based on Al and mobile technology and con sists of two planks: First: - trai n an Al to be able to detect COVID-19 by measurements tha t can be done by cell phone (for example pictures of patients, recordings of patient's respiratory system) Second: - develop and release a smart -phone applicat ion that does the following: NIH-001828 - turns on location tracking so health authorities can see where the cell phone owner is. - allows for people to upload health measurements from their cell phone . - keeps TRACKof where the cell phone owner is. If that person then tests positive for COVID later on, it can then automatically figure out all the contacts of that person for the last 14 days. - notifies those contacts that they have been in contact with someone with COVID- 19, to isolate themselves and regularly test themselves. The goal would be to prevent hundreds of thousands of people from descending on hospitals and overwhelming them, and to allow for the CDCor other medical personnel to go OUT and get them - or isolate them for treatment in their own homes - rather than having them come in and infect everybody. Now this all hinges on the idea that Al could detect COVID-19 based on an audio recording or a simple picture and do it reliably, but I'm fairly sure that it can based of the peer-reviewed lite rature. It is not a difficult Al problem assuming that the microphone can pick up sounds well enough - if not, there are already integrated stethoscopes for cell phones that could be mass produced - and once developed to enough precision it could be deployed nationally or internationally fairly easily. For all I know something like this is already in the works but I haven't heard of anything like it - apart from the chinese app which AFAICTdoes not use any Al but DOESallow for automatic contact tracing. I sincerely hope th is is already in the works. Ultimately it could be used both for detection and treatment - assuming the current antivirals work out they could be distr ibuted to the same coordinates that positive diagnoses come in, perhaps by cheap drone so that nobody actually needs to be exposed to the virus to effect treatment . Anyways, thanks for your time and efforts. Personally I'm a software developer but I'm hop ing that perspective his helpful - for I view the fight against this virus as an INFORMATIONALfight. It's like a fire suppression system or food safety measures. Again, I have no clue whether or not this is already being done, and I apologize in advance if I'm missing something and this all seems obvious. I just think that in th is case it is prudent for us to be safe rather than sorry. Thanks much, Ed NIH-001829 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 202017:42:47 +0000 Conrad, Patricia (NIH/NIAID) [El FW: PBSNewsHour inquiry for today FYI Let us discuss after I get off the AMA call, which is going long From: David Coles Se nt : Monday, February 17, 2020 11:51 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: PBSNewsHour inqui ry for today ------~~ -------- (b)( > Dr. Fauci, Might you be available to update our viewers on the latest developments in the coronav irus story today/tonight? We are particularly interested in getting your evaluation of the passengers who have been released from two cruise ships. The first, in Yokohama, Japan, where over 300 Americans released from the ship have now arrived back in the US, to go into 14 days of quarantine. 14 of those people t ested positive at some point after leaving the ship, but before they boarded the plane . The second ship we want to focus on is in Cambodia. Something in the neighborhood of 1,000 passengers released from that ship have been reported to be in some state of travel to their homes, presumably around the globe. One woman who made it as far as Malaysia tested positive there and is hospitalized in Kuala Lumpur. We do know that the CDCis working with WHO and the cruise ship line to track down those traveling people . We would ve ry much like to hear from you what level of concern we should have over those many hundreds of people traveling right now, how well quarantine works, how important it is to maintain it , etc. We would also like to touch on the methods of containment and treatment being done inside China and how well those methods have worked. I realize it is a holiday, and that could complicate things. But please let me know whether you could consider this, Doctor, and we wi ll begin to work out the logist ics. Thank you. Very best regards, Dave David Coles Deputy Senior Producer, National Affairs () PBSNEWSHOUR 703 998 2104 NIH-001830 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon, 17 Feb 2020 16:35:20 +0000 Smith, Steven Re: i've been th inking about you image003.png Steven: Thanks for the note. Much appreciated. It has been 24/7 for me for the past 4 weeks. Hop e that all is well with you. Best, Tony On Feb 17, 2020, at 10:39 AM , Smith , Steven < ..... wrote: Having just come back from Australia where coronavirus is hands down a national emergency, I've been thinking about you again and all the good work you do to keep us safe. I was with someone who's a diplomat with the Australian government who said "it's much, much worse than the Chinese would have you believe. Much worse." Melbourne and Sydney were deserted almost immediately of Chinese tourists and students. I luckily flew through DOHA. Hang in there. It's always something. Steven Steven W. Smith (b)(6) ~ (b)(6) This message , including attachments, is confidential and may be privileged. If you received this in error. pleasenotify me by reply email and delete this messaae . (b)(6) NIH-00183 1 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 14:14:34 +0000 Conrad, Patricia (NIH/NIAID) [E) Re: Request from CNN's New Day image001 .jpg Thanks On Feb 17, 2020 , at 9: 11 AM , Conrad, Patr icia (NIH/N IAID ) [E] (b) (6) wrot e: Working on this from med arts for tomorrow as well. Just FYI Sent from my iPhon e Begi n forward ed message: From: "Figliola , Mike" Date: Februar y 17, 2020 at 8:42:38 AM EST To: "Conrad, Patric ia (NI H/NIAID) [E]" Subject: RE: Request from CNN's New Day ,--------- ---------- ~= (b) < Copy will be back soonest M Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike .figliola@turner .com CON FIDENTIALITY NOTICE : This e-ma il transmission , and any documents, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged . If you are not the intended recipient , or a person responsi ble for delive ring it to the intended recipient , you are hereby notified that any disclos ure, copy ing, distrib ution or use of any of the informatio n contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please NIH-001833 immediately notify us by reply e-mai l at mike.figliola@turner. com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. (b)(6)> From: Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:42 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day --------- Between 7 am - 7:50 am ET From: Figliola, Mike Se nt : Monday, February 17, 2020 8:40 AM To: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: Request from CNN's New Day ------- --------- Working on timing- ~~ > (b)( is there a preferred time? Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike .figliola@turner .com CONF IDENTIALITY NOTICE: This e-ma il transmission , and any documents , files or previous e-mail messages attached to it, may contain confident ial information that is legally privileged. If you are not the intended recipient, or a person responsible for delivering it to the intended recipient. you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figl iola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments without reading them or saving them to disk . Thank you. From: Conrad, Patricia (NIH/NIAID) [El Se nt : Monday, February 17, 2020 8:40 AM To: Figliola, Mike Subject: Re: Request from CNN's New Day Would hit time be I. The 7 am hour? Do I have exact time? Sent from my iPhone NIH-001834 (b)(6) On Feb 17, 2020, at 4:16 AM, Figliola, Mike wrote: Hi Patty, Mike with cnn and new day here Hope all is well We are interested in checking Dr Fauci's availability for Tuesday's show. May you let me know if he is avail and what time frame works best? Topic is Coronavirus Thanks! M Sent from my iPhone On Jan 30, 2020, at 10:05 AM, Figliola, Mike wrote: Hi Patty! Morning If we want Fauci for tomorrow, is he avail? Barring maj breaking news we are not planning to cancel Thoughts? M Mi ke Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner .com NIH-001835 CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delive ring it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at mike.fiq liola@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Figliola, Mike Date: Thursday, January 23, 2020 10:22 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Copy thank you! Mike Figliola Edito rial Producer CNN's New Day (b)(6) mike .fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission , and any documen ts, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike.figliola@turne r.com or by telephone at (917) 670-9410, and destroy the original transmission NIH-001836 and its attachments without reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, January 23, 2020 10:16 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Per our chat just now - can have him avail between 6 am - 8:15. Hard stop at 815 am ET Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectiou s Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behal f of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 10:02 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6) Subject: RE: Request from CNN's New Day Ok- we wont know until 1030a meeting - is it ok to hold 6 and 7a until then? Mike Figliola NIH-001837 Editorial Producer CNN 's New Day (b)(6) mike.figlio la@turne r.com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged. If you are not the intended recipient, or a person responsib le for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribu tion or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED . If you have received this transmission in error, please immediately notify us by reply e-mail at m ike.figliola@turne r.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thur sday, January 23, 2020 10:00 AM To: Figliola, Mike Subject: RE: Request from CNN's New Day Sorry to be a pain-if you think it will be in the 6 am hour - we might need to use a diff erent studi o ...if its in th e 7 am hou r we can use our remote studio ... Any thoughts as to which hour again, sorry Patricia L. Conrad Public Health Analyst and Special Assista nt to the Director Nation al Institute of Allergy and Infectious Diseases Th e National Inst itutes of Health 3 1 Center Driv e, MSC 2520 - Room 7A03 NIH-001838 Bethesda, M aryland 20892 (b)(6) 30 1-496-4409 fax Discla imer: The information in this e-mail and any of its attachments is co nfidential and may contain sensit ive informati on. It should not be used by anyo ne who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any othe r storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sende r's own and not expressly made on beha lf of the NIAID by one of its representatives . From: Figliola , Mike Date: Thursday, January 23, 2020 9:23 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Request from CNN's New Day Copy thank you Mike Figliola Editoria l Producer CNN 's New Day (b)(6) mike.figlio la@turner .com CONF IDENTIALITY NOTICE: This e-mail transmissio n, and any documents, files or previous e-mail messages attached to it, may contai n confidentia l information that is legally privileged . If you are not the intended recipient, or a person respons ible for delivering it to the intend ed recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICT LY PROHIBITED . If you have received this transmission in error, please immediately notify us by reply e-mai l at mike.figlio la@turner .com or by telephone at (917) 670-9410, and destroy the original transmission and its attachme nts withou t reading them o r saving them to disk. Than k you. NIH-00183 9 From: Conrad, Patricia (NIH/NIAID) [E] (b) ~ > Date: Thursday, January 23, 2020 9:18 AM To: Figliola, Mike Subject: RE:Request from CNN's New Day Checking now for all t imes between 69 will let you know soonest Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infe ctious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensit ive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Figliola, Mike Date: Thursday, January 23, 2020 9:10 AM To: Conrad, Patricia (NIH/NIA ID) [El (b)(6) Subject: RE:Request from CNN's New Day Hi again Could be back half of 7am but if this gets much worse we may play it higher in the hour - is there any time that doesn't work? Mike Figliola Editorial Producer CNN 's New Day (b)(6) NIH-001840 mike.fiqliola@turner .com CONFIDENT IALITY NOTICE: This e-mail transmission, and any documents, files or previous e-mail messages attached to it, may contain confidential information that is legally privileged . If you are not the intended recipient, or a person responsible for delivering it to the intended recipien t, you are hereby notified that any disclosure , copying, distribution or use of any of the information contained in or attached to this message is STRICTLY PROHIB ITED. If you have received this transmission in error , please immediately notify us by reply e-mail at mike.fiqliola@turner.com or by telephone at (917) 670-9410, and destroy the original transmission and its attachments withou t reading them or saving them to disk. Thank you. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Thursday, January 23, 2020 8:57 AM To: Figliola, Mike Subject: FW: Request from CNN's New Day Hi Mike - we can make this happen . The 7 am hour is best for us but will get back to you. do you have an idea of the hit t ime? need to make sure our nih studio is available. thx Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax NIH-00184 1 Disc laime r: The informat ion in this e-mail and any of its attachmen ts is confidential and may conta in sensitive informat ion. It sho uld not be used by anyone who is not the original intended recip ient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . Begin forwarded message: From: "Figliola , Mike" Date: January 23, 2020 at 8 :36:15 AM EST To: "Fauci, Ant hony (NIH/NIAID) [E]" (b)(6) Subject: RE: Request from CNN's New Day Hi everyone, This is Mike with CNN's New Day Hope yo u are well We would like t o invit e Dr, Fauci back to the program to discuss coronavirus Might he be availab le tomorrow We air 6-9am and happy to provide car service to and from the stud io wherever you are located . John Berman and Alisyn Camerota anchor f rom NY. Thoughts? best, M NIH-001842 Mike Figliola Editorial Producer CNN 's New Day (b)(6) mike.figliola@turner.com CONF IDENTIALITY NOT ICE: This email transmission, and any documen ts, files or previous e-mail messages attached to it, may contain confident ial informatio n that is legally privileged. If you are not the intended recipient, or a person responsible for deliver ing it to the intended recipient , you are hereby notified that any disclosure, copying , distribution or use of any of the information contained in or attached to this message is STRICTLY PROH IBITED. If you have received this transmission in error, please immediately notify us by reply e-mail at mike .figliola@turner.com or by telephone at (917) 670-9410 , and destroy the original transmission and its attachments w ithout reading them or saving them to disk. Thank you. NIH-001843 m NIH-001844 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 202013:50:10 +0000 Natalie Rahhal Kadlec, Robert (OS/ ASPR/10) FW: Comments re: 14 US passengers with coronavirus and updates To: Cc: Subject: Nata lie : I sent the incorrect e- ma il address for Dr. Kadlec. Here is the correct one. Tony From: Fauci, Anthony (NIH/N IAID) [E] Se nt : Monday, February 17, 2020 8:47 AM To: Natalie Rahhal (b)(6)> Cc: (b)( ·; Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Comments re : 14 US passengers with coronavi rus and updates --------- N ata lie: Thank you for your note. (b)( > Dr. Robert Kadlec, the Assistant Secretary for Preparedness and Response (ASPR) at HHS could either answer this question or point you in the direction someone who could. I am copying him on this e-mail. of Best regards, Tony (b)(6) From: Natalie Rahhal Date: Monday, February 17, 2020 8:28 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Comments re: 14 US passengers with coronavirus and updates ------------ ------~= Hi Dr Fauci, I hope this note finds you well and that you've gotten a little rest over the weekend, during what I'm sure is an inordinately busy time . Would you be able to elaborate on the measures taken to keep the 14 US evacuees who have coronavi rus from infecting others on board the plane? I know that remdesivir, under compassionate use, was given to at least the first Amer ican coronavirus patient, and last week NIH researchers published results early that it had preventive effec t s for macaques exposed to MERS. Has the US considered using this drug to protect those exposed to but not yet infected with coronavirus? Thank you, Natalie A Rahhal Acting USHealth Editor Daily lltail.com - NIH-001845 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001846 Fauci, Anthony (NIH/NIAI0) [E) Mon, 17 Feb 202013:24:34 +0000 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Doepel, Laurie (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID ) [E);Marston, Hilary (NIH/NIAID) [El Subject: RE:ASF ------ attached for your rev iew is draft abstract for Florence vaccine meet ing Attachments : Keystone abstract --transform ing vaccinology- - 3-16-2020 - with minor Fauci edits.docx From: Date: Greg: This looks great. I have made some min or edits that are trac ked in the document. accept these and then it is ready to go. Thanks. Please Best, Tony From: Folkers, Greg (NIH/N IAID) [El --------- (b)(6) Date: Wed nesday, February 12, 2020 1:47 PM ------~= To: Fauci, Anthony (NIH/NIAID) (E] Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( 6)> (b)(6) >; Doepel, Laurie (NIH/NIAID) [E] Eisinger, Robert (NIH/NIAID) [E) (b)( ; Folkers, Greg (NIH/NIAID) [E] CbH6J ; Lerner, Andrea {NIH/NIAID) [El (b)(6); Marston, Hilary {NIH/NIAID) [E] (b116)1> Subject: ASF ------ attached for you r review is draft abstract for Florence vaccine meet ing (b)(6)>; Disclaimer : Any third -party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracit) '. It does not necessarily repre sent my views nor tbose of NlAlD, NIH, HHS, or th e U.S. government. NIH-001847 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 16 Feb 2020 22:28:19 +0000 Jon LaPook RE:Coronavirus Jon: I have no idea what this guy is talking about. 1 have never said the RO was close to 5 or 6. The RO is about 2.0 to 2.2. Also, the situation is as we have discussed on several occasions . In the USA, the travel restrictions seem to be working with only 15 cases in the USA (13 travel and 2 spouses) . But, as I have said, this could change. Ifwe get substantial sustained transmission in a numbe r of countries throughout the world, including the developing world, then sooner or later there will be significant leakage of infect ed individuals into the US A since you can not restr ict inco ming travel from the w hole woild. T he way we might be able to avoid a real globa l pandemic is if t he non -Chfoa countr ies can co nta in the infect ions in their respec tive count ries before there is widely distrib uted sustained transmissions. Once w idely d istributed sustained transmissions happen, a g loba l pandemic is inevitable. What would a global pand emic mean? ft depends on the true rate s of morbidity and mortality. The curre nt ly repo rted mortality of COVI D-19 is about 21/o. However, there are seve ra l folds more cases than a re com in g to the official attention of h ea lth autho1ities, i.e . asymptomatic or minima lly symptomatic in fections . If yo u cou nt these, the denominator gets much larger and the case fa ta lity rate could drop to 1% of even 0 .5 % or less. If that is the case, then this could be a very severe seasona l flu (0.2% to 0.4% ; regular seaso nal flu is 0.1 %) or a typical pandemic lik e 1957 or 1968 (0.5% -0.9 %). We are not sur e w here it is goi ng to land . Hope this is helpful . Best, Tony Anthony S. Fauci, MD D irector National lnstih1te of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-252 0 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The informatio n in this e-mail and any of its attachments is confidential and may contain sensitive infom1at ion. It should not be used by anyone w ho is n ot the o rig inal intended recipie nt . lfyou have received this e-ma il in e rror ple ase inform the se nder and delet e it from your mailbox or any ot her storage devices. T he Nationa l Institute of Allergy and Jnfectio u~ Diseas es (NTAID) shall not accept liability for any stateme nts made that ar e the sender's ow n and not expr essly made on behalf of the NIAID by one of its representatives. ---- -Original Message- ---Fr om: Jon LaPook ______ __,(b""' )..,. (= > Date: Sunday, February 16, 2020 4:39 PM To: F auci, Ant hon y (NI H/NIAID) [El Subject: Coronavirus -------.,; == --------(b)( Hi Tony, l thought you would be interested to see a text (be lo w my ema il) I j ust got from a very smart Wall Street guy who has been filling me in on reaction there. l 've been doing my best on air to put the current situation in perspective communicating that the risk in the U .S . is still re lative ly low while letting viewers know the situation is fluid and could change. How would you sum up where we are now? Thanks , Jon NIH-001848 TEXT I JUST RECEIVED: "Doc, total panic mode setting in . Tony Fauci talking R nought at closer to 5 or 6. Good biotech guys saying it might not die down in April. People talking about 60% ofus will get it ; unstoppable in Africa. r can't scare people but this is really bad. I hate bothering you on this but I know I need to take my cue from what you will say on CBS" Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Health Twitte r @DrLaPo ok NIH-001849 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 21:16:02 +0000 Lucassen,Elisabeth B RE: Coronavirus patient--secure Elisabet h: Do yo u have t ime for a qu ick ph one call? Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lucassen,Elisabeth B Date: Friday, February 14, 2020 1:54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subj ect : Coronavirus patient--secure Impo rt anc e: High -------=---c-c= Dear Dr. Fauci, (b)(6) NIH-00185 0 (b)(6) ------- (b)(6) _ Any input would be mostappreciated.Many thanksin advance! Sincerely, ElisabethLucassen This message is intended for the sole use of the addressee , and may contain information that is privileged, oonfldential and exempt from disclosure under applicablelaw. If you are not the addressee you are herebynotified that you may not use, copy, disclose.or distribute to anyonethe messageor any information contained in the message.If you havereceivedthis messagein error, please immediately advise the senderby replyemail and delete this message. NIH-001851 From: Date: To: Cc: Attachments : accepted.docx Fauci, Anthony (NIH/NIAIO) [E) Sun, 16 Feb 2020 20:40:58 +0000 Redfield, Robert R. (CDC/OD) Greg Folkers (b) ( ·) nejmoa2001316.pdf, NEJM Editorial - Fauci et al - clean with Fauci edits Bob: As per our discussion, I am attaching the Editoria l together with the NEJM paper upon which t he editorial is base d . Please take a look and give your approval. Of course if you have any comm ents or edits, th ey are most welcome. As mentioned, the NEJM wants the manuscript by COB tomorrow (Monday). Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892 -2520 Phone: (b)(6) FAX:(301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001852 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 16 Feb 2020 20:20:29 +0000 Arthos, James (NIH/NIAID) [E) RE: one on one No prob lem. I am drowning in coronavirus and our meeting likely would have wound up being cancelled anyway. Hopefu lly, we will soon get back to some sort of normality in our meetings. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Arthos, James (NIH/NIAID) [El Date: Sunday, February 16, 2020 2:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -------=-,--=, Subject: one on one -------- (b)(6) Hi Tony , I'm very sorry to bother you when you are so busy. Regarding this Tuesday, we are on your schedule for a one on one and unit head meeting. something came up last minute andl am going to be away from Tuesday through Friday, so I won't be able to make either. Sorry for the late notice. Jim NIH-001853 From: Date: To: Fauci,Anthony (NIH/NIAIO)[E) Sun, 16 Feb 2020 20:17:53 +0000 Lane,Cliff (NIH/NIAID) [El Gr eg Folker s (b)(6)c, Conrad, Patricia (NIH/N IAID) [El Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth additional Fauciedits - 02-152020.docx, NEJM Editorial - Fauciet al - clean wit h Fauci edits accepted.docx Cc: Cliff ; I am attaching 2 documents: 1) The revised manuscript t hat Greg worked on in which I have added a number of t racked changes including deleting a substantial amount to get it between 800 and 900 words; and 2) A clean vers ion where I have accepted all the t racked changes (Greg's and mine). Right now I lik e it the way it is and would not change it much if at all. What it needs now is references. Greg will take a shot at adding the references . If you have references, please send them to Greg and me. In the meant ime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish. Than ks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-001854 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sun, 16 Feb 2020 19:19:00 +0000 To: Greg Folkers (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: NEJM manuscript Attachments: NEJM Editorial - Fauci et al - clean wuth addit ional Fauci edits - 02- 152020 .docx, NEJM Editorial - Fauci et al - clean wi t h Fauci edits accepted.docx Greg; I am attaching 2 documents: 1) The revised manuscript that you sent to me in which I have added a number of tracked changes includ ing deleting a substantial amount to get it between 800 and 900 words; and 2) A clean version where I have accepted all the tracked changes (yours and mine. Right now I like it the way it is and would not change it much if at all. What it needs now is references. Can you add up to 10 references? It might be easier for you to do that rather than Cliff. If not, I will send to Cliff and see if he can do it. In the meantime, I will send it without references to Bob Redfield for his review/approval. Let us discuss by phone if you wish . Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e -mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . NIH-001855 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 16 Feb 2020 12:12:58 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: COVID-19 therapy Please handle. ----- Original Message ----From: Cesare Cocchi _______ _.,(b ,..,, ~...,. (6) => Date: Sunday, February 16, 2020 5:18 AM To: Fauci , Anthony (NIH/NIAID) [E] ..._ _____ -----~~= (b _)_C_,> Subject: COVTD-19therapy Dear Doctor Fauci, J am a pediatrician from (b)(6) (IT) . J was wondering if high doses of vitamin A have been tried in the therapy of COVID- 19. Do you remember the cases of viral pneumonia due to measles that take place in African infants in the late seventies. Jt seemed to work. Many sorry to bother you. Have a good job! Best regards Cesare Coccbi MD NIH-001856 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 22:21:34 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: To VIMA newspaper-Greece-interview request-coronavirus FYI -----OriginalMessage----From: 0woropa Tcrw1c11 Date: Saturday , February 15, 2020 4:22 PM To: NlAID NEWS (NJH/NJATD) Cc: Fauci , Anthony (NTH/NIAID) [E] Subje ct: To VIMA newsp aper-Greece-interview (b)(6) > request-coronavirus Hallo My name is Th eodora Tsoli and I am a sc ience editor for the greck newspaper To VIMA (www .tovima.gr )one of the biggest Sunday papers in my country.I would like lo hav e,ifpo ss ible,a telephon e interview with dr Fauci on the corona virus outbreak for next Sunday' s paper.If he won't be ab le to speak ,could 1 sen d question s to which he could answer? Looking fotward to yo ur reply Thank you in advance Theodora Tsoli :EtaA0l'lKE arr6 to iPhone µou :E1iµavnK6: llapaKcu.ro8Eite111voi]1ccocrn anonoincrnc;1m8uvrov Important: Please read our disclaimer NIH-001857 From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Cc: (NIH/N IAID) [El Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 22:05:41 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia RE: FORASF REVIEW:Draft PR re: launch of ACTT 2 COVIO treatment study See my minor change of my comment in red. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: __ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)( 6)r> Date: Tuesday, May 5, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Billet , Courtney {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _ C6); Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW: Draft PR re: launch of ACTT 2 COVID treatment study ------ ::;..,..-,= ';::::=====~~ Hi Dr. Fauci, Please find at tached fo r your review a draft press release to announce the launch of the ACTT 2 COVID- 19 treatment trial (remdesivir and baricitinib). Below is your draft quote: "We now have solid data showing that remdesiv ir dimin ishes to a modest degree the time to recovery for people hospitalized with COYID-1 9," said NlAID Director Anthony S. Fauci, M.D. "AC TT 2 will examine if adding an anti-inflamma tory agent to the remdes ivir regimen can prov ide addi tional benefit for patients , including improv ing morta lity outcome s." The trial may start enrollment tomorrow. Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Attachme nts: Fauci,Anthony (NIH/NIAID) [El Tue, 5 May 2020 22:00:53 +0000 Cassetti,Cristina (NIH/NIAID) [El FW: COVID-19, (b)( 4) Bi rman_Fauci_Aza r_Adams_Hahn_letter _May _OS_2020.docx Please take a look at this. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A -03 31 Center Drive , MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please infonn the sender and delete it from your mai lbox or any other storage devices. The National Institut e of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Messag'-e_- -_-------~~ From: (b)(4 Date: Tuesday, May 5, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Azar, Alex M. (b)(6) > ; Adams , Jero me M .,_.,....,.._..,,...,,,,.........,...,..,.,.-,--,..,...., ------=-:--:-::, --------- (b) ( ; Hahn , Stephen (FDA) (b)(6) Subject: RE:COVID-19 , -------- (b)( 4) Dr. Anthony S. Fauci , M.D. Director , NIATD Mr. Alex M . Azar TI Secretary , HHS Dr. Jerome M. Adam s, M.D. Surgeon General , HHS Dr. Stephen M. Hahn, M.D. Commissioner of FDA , HHS Dear Dear Dear Dear Dr. Fauci , Mr. Azar, Dr. Adams, Dr. Hahn, (b) (4) (b)(4 From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 5 May 2020 21:17:33 +0000 To: Ma scola, John (NIH/VRC) [El Cc: Conrad, Patricia (NIH/N IAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Dieffen bach, Carl (NIH/NIAID) [E];Marsto n, Hilary (NIH/NIAID) [E];Billet, Court ney (NIH/N IAID) [E);Graham, Barney (NIH/VRC) [E];Marovich , Mary (NIH/NIAID) [E] Subject: RE: 0614G mutation paper (b) (5) Than ks, Jo hn . (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] CbH > Date: Tuesday, May 5, 2020 5:0 4 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)( ; Erbelding, Emily (NIH/NIAID) [E] (b)(6) ; Dieffenbach , Carl {NIH/NIAID ) [E] (b)( 6)f>; Marston , Hilary (NIH/NIAID) [E] (b)( >; Billet, Courtney (NIH/NIAID) [E] ------~= Cb _H _6); Graham, Barney (NIH/VRC) [El (NIH/N IAID) [El (b)(6) Subject: FW: 0614G mutation paper -----=~ (b)( 6)> ; Marovic h, Mary Tony, David M ontefio ri w ill be on CNN tonigh t related to t his paper - and sto ry in in majo r newspapers. spoke with David to get some advance info . The paper is out in BioRxiV. Few key points (b) (5) John Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Korber 81, FischerWM 1, GnanakaranS1, Yoon Ht, Theiler Ji, Abfalterer Wt , Foley 8 1, GiorgiEEi, Bhattacharya T1, Parke r M0 3, Partridg e DG4, Evans CM 4, de Silva Tl4,s, on beh alf of t he Sheffi eld COVID -19 Ge nomics Group #, LaBranche CC2, and Mont efiori DC2 Summary We have developed an analysis pipelin e to facilitate real-time mutation tracking in SARS-CoV-2, focusing initia lly on the Spike (S) protein because it mediates infect ion of human cells and is the target of most vaccine strategies and antibody-based therapeutics. To date we have identified fourteen mutations in Spike that are accumulating. Mutations are considered in a broader phylogenetic context, geographically , and over time, to provide an early warn ing system to reveal mutations that may confer selective advantages in transmissio n or resistance to interventions. Each one is evaluated for evidence of positive selection, and the implications of the mutation are explored t hrough structural modeling . The mutation Spike 0614G is of urgent concern; it began spreading in Europe in early February, and when introduced to new regions it rapidly becomes the dominant form . Also, we present evidence of recombination between locally circulating strains, indicative of multiple stra in infections . These finding have important implications for SARS-CoV - 2 transmission, pathogenesis and immune interventions . From: David Montefiori, Ph.D. Date: Tuesday, May 5, 2020 1:23 PM To: Mascola, John (NIH/VRC) [E]______ ----------- Subject: RE: 0614G John , (b)(6) --,;-(b"'""' )( =6) I thought you should know that the 0614G story is getting a lot of press attention today. I story came out in the LA Times this morning that probably started it all. It will likely be on CNN tonight , and maybe other networks. Just a heads-up. David From: Date: To: Subject: Attachments : Fauci, Ant hony (NIH/ NIA ID) [E) Tue, 5 May 2020 20:43:3 9 +0000 Bill et, Courtn ey (NIH/ NIA ID) [E];N IA ID OD AM RE: Dr. Anth o ny Fauci & Avi Schiffm an/T he Webby Awards Scri pt to honor Avi Schiff mann - 05-05-202 0.docx Here is my tracked version of the Schiffmann script. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6) > From: Billet, Courtney (NIH/N IAID) [E] Date: Tuesday, May 5, 2020 3:06 PM To: NIAID OD AM Subject: FW: Dr. Ant hony Fauci & Avi Schiffm an/The W ebby Awards -------- OK- so th is is the ask from the Webby awards : a short recorded video message. They have sent a propo sed scri pt below -- just an example - obvious ly we're free to change it . Avi is a pretty extrao rdinary kid . 17 years old I Here is th e site he create d, back in early January. He's aggregati ng data from W HO, CDC, and ot her sources: https:ljncov2019. live/ NBCToday st ory: https://www.toda y.com/parents/17-vear -old -built -website -track-coronavirus t175 245 New Yo rker art icle about him: https://www.newyorker.com/magazine/2020/03/30/the -high-schoolerwho-beca me-a-covid-19-watchdog From: lesley lesleycahill roy. com Date: Tuesday, May 5, 2020 2:32 PM To: Billet, Courtney {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E]________ > Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ==========:,::.:= HI Courtney, This would be a pre-recorded messagewith Dr Fauci solo . He would set up Avi's award and help to celebrate his Webby moment for him. Avi will be sending us his 5 word Webby speech which will then follow Dr. Fauci's intro . Below is a draft of the introduc tion for him, let us know if he would like to make any edits/changes. I've also attached the format for taping on his phone/computer. Please let me know if you need any additional information and hoping we can make it work . Thank you so much Best Lesley DR. FAUCI: I'm Dr. Anthony Fauci. Unfortunately, you've seen a lot of me lately . But thankfully, I'm here to present some good news and I'm excited for the opportunity to shine some light on one of the many young people who have stepped up and helped us throughout a difficult time. The 24t h Annual Webby Awards would like to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world. As we collectively navigate the severe impact of COVID-19, including the difficult, but critica l calls for nationwide social distancing, the Internet has become the lifeblood of people looking for accurate information about the novel coronavirus and the necessary steps to combat it. Since launching the site on December 29th, Schiffmann ' s tracking tool has been an invaluable resource that sounded the alarm on the virus and its spread, notably calling attention to its severity long before many global officials . At a time when the spread of misinformation can be so detrimental to our efforts, the site has provided over 600 million visitors wit h accurate real-t ime data. Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and the importance of measures to flatten the curve . For having the foresight to track the global spread of COVID-19 and for creating an essential website to provide real-time data about the virus to people everywhere , it is my great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. --------- On May 5, 2020, at 10:31 AM, Billet, Courtney (NIH/NIAID) [El wrote: (b)(6) Lesley- we've been discussing this. Can you tell us exactly what would be involved in this? How many minutes would you be looking for Dr. Fauci to speak? Would this be prerecorded, with Dr. Fauci solo? Or would it be done as a Zoom or something like that, wit h an interaction between Dr. Fauci and Avi? From: Billet, Courtney (NIH/NIAID) [El Date: Monday, May 4, 2020 5:31 PM To: lesley lesleycahillroy.com Cc: Conrad, Patricia (NIH/NIA ID) [E) (b)(6)> Subject: RE: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Lesley- thanks so much for reaching out. Avi is so impre ssive! I am connecting you with Dr. Fauci's assistant and scheduler, Patty Conrad, for follow-up. From: lesley lesleycahillroy.com Date: Monday, May 4, 2020 5:10 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: Fwd: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards ------ --= Hi Courtney, Hope you are staying well during these uncertain times . I am a Talent Producer for The Webby Awards and had reached out to Dr. Fauci regarding being involved in our "vir tua l" internet celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, educat ion, movement, comedy, all whi le inspiring audiences to take action to enact positive change. Avi Schiffman is being celebrated as our Person of the Year and we would be honored if Dr Fauci wou ld "virtually" present him his honor. The official letter is below and would love to discuss in more detail when you have a chance to review. Thank you Best Lesley Begin forwarded message: From: Les ley Cah ill Roy Subj ect: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards Date: May 1, 2020 at 12:13: 10 PM EDT To: CbH6) HI Dr Fauci I just wanted to follow up on below regarding Avi and The Webby Awards . Would be wonderful if you could be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahil lroy.com wrote: <6EDD370A-6106-4603-B55 7-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and t he family are all safe and healthy during t hese challenging times. Hailed by The New York Times as "the Internet's highest honor," The Webby Awards has been the premiere award fo r online excellence for over two decades, honoring t he companies and people who have critically shaped digital technology and culture . This year, due to the impact of the coronavirus The Web by Awards are moving t hei r renowned awa rd show to an on line experience . On May 19th, 2020, the 24th Annual Webby Awards will bring togetherWebby Winners from around the world in an Internet Celebration wh ich will showcase the artists, organizations, and creators using their platforms to imagine a better tomorrow through information, education, movement, comedy, all while inspiring audiences to take action to enact positive change . The 24th Annual Webby Awards are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.live to track the spread of COVID-19 across the world . We would be honored if Dr. Fauci would "virtually" present Avi with his award. As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing , the Internet has become the lifeblood for people looking for accurate information about the novel coronav irus. Since launching the site on December 29th , Avi Schiffmann' s tr acking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real -time data on the virus' spread, Schiffmann has helped peopl e around the globe understand COVID-19 and the necessity of upgrades to current health care systems and measures to flatten the curve. For having the foresight to track the global spread of COVID-19 and for creating a website to provide real -time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5Word acceptance speech in Internet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Awards will also take action, the impact of COVID-19 and government responses around the world, has brought the importance of voting into sharp focus . The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure voter turnout this November is the highest it has ever been . This partnership will integrate into all elements of this year's online celebration. Our thoughts are with all of you in this difficult t ime. Best LesleyCahill Roy (b)(6) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 5 May 2020 19:49:36 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El FW: unlikely Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Th e National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Konstantin Vulkov Date: Tuesday, May 5, 2020 3:42 PM To: NIAID NEWS (NIH/NIAID) Cc: NIAID Ocpostoffice (NIH/NIAID) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Harper, Jill (NIH/NIAID) [El Cb)( > -------Subject: Dear Sir/ M adam , My name is Konstantin Vulkov and I am Program director of the biggest Bulgarian private radio station, Darik radio (www .darikradio.bg). This is a news/talk radio station . I am a regular contributo r to Bulgarian National TV as w ell as several on line and print publ ications , editor -in -chief of egoist.bg as well as editor in-chief of the biannual Darik-owned publication called Dolce Far Niente . I am a document photographer as well , focusing mainly on portraits . I am covering the coronavirus pandemic extensively - visiting COVID-19units across the country, making my daily radio programme "Mind games", writing stories for our websites www.darikradio.bg. www.dnews.bgand egoist.bg. It would be an honour if I can make a short te leph o ne int erview with Mr. Anthony S. Fauci, M .D. Please let me know if I can call and make the interview . I promise I won't take more than 10 minutes of Mr. Fauci's time . Your help is much appreciated. Best, Konstantin *** Konstantin Vulkov Program Director Darik Radio 82, Dondukov blvd. Sofia 1504 Bulgaria From: Date: To: Subject: Fauci, Anthony {NIH/NIAID) [E] Tue, 5 May 2020 19:48 :10 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: AUSTRIA- Try to support - COVID 19 - Strategy Looks fin e. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID ) [E) Date: Tuesday , May 5, 2020 3:37 PM To: Fauci, Anthony {NIH/NIAID ) [E)_____ (b)(6) ---,;;(b..,.. ~= c > Subject: Re: AUSTRIA - Try to support -COVID 19 - Strategy Dr . Fauci, I will respond. Here is what I propose to say {in addition to thanki ng him) . Let me know if you'd change anything: (b) (5) Sincerely , Andrea From: "Fauci, Anthony {NIH/NIAID) [E]" (b)(6) Date: Tuesday, May 5, 2020 at 10 :40 AM To: "Lerner, Andrea (NIH/NIA ID) [E]" (b)(6) Subject: Fwd: AUSTRIA - Try to support - COVID 19 - Strategy -------. =, Not a crazy note. Please respond on my behalf. Thanks Begin forwarded message: Froml (b)(6) Date: May 5, 2020 at 8:19:48 AM EDT To: "Fauci, Anthony {NIH/NIAID) [E]" -------,; (b-,-.)(=6) Subject: AUSTRIA - Try to support - COVID 19 - Strategy Dear - highly respected - Dr. Fauci Why do I try to childishly support a respected expert and personally highly honored Gentleman like you - Dr. Fauxi ? Because for me - it is heartbreaking and unbelievably disturbing, what was and is going on in the course of the last 4 months in the USA. I talk about the USA, that relieved my country - AUSTRIA - 75 years ago from the hell of the NAZI-Regime - with American Lifes and Blood. With all my respect, my hopes, my passion, my tears, my mourningMay Grace and Blessing be with You and the USA. After running the numbers available on COVID 19 pandemic data - my experiences as an Economist led to following analysis and proposed strategy: COVID 19 is a true threat for humans >65 years of age with preexisting illnesses, but nearly influenza-like for humans< 65 years of age and humans> 65 years of age without pre -existing illnesses AUSTRIA: Deaths by age Deaths as of 100.000 inhabitants by age Germany- Death by age - men and women - mortality rat e in % Comparison - Italy and China . .,_ (3:fri,fi?@D~hr ---Id MJnntr untcr don To~n 1"\,t,"MII-,. Jr.;CC! --~-~~~~~- C..,,lt•lt-fent11 Obtt 80 J•hrt • 52,3% Proposed Strategy 1. Keep the virus 100% (totally) away from people older than 60 with pre-existing illnesses Identify, Testing, Shelter, Preserve from contact w ith v irus, Preserve from Hospitalizat ion and ICU 2 . Minimize possible contact with virus for people older than 60 without pre-existing illnesses Identify , Testing, Partial Stay at Home, Social Distancing,, Preserve from Hospitalization and ICU Once 1 and 2 are warranted: 3. Handle the rest of the population with care, but keep them going and working - as you would do in an influenza -season The criti cal fact or for furth er int ervent ion is th e capacit y of th e region ally available ICU-capacit y Interventions : Social Distancing, Masks, Testing, Tracing, Stay at home when ill, Quarantine at home when ill Respectfully Yours Gerald Glockenstein Ma . Gerald Glockenstein (b)(6) From: Date: (b)(6) To: Subject: Tue, 5 May 2020 10:47:11-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Please try to get clearance. This is tb.etop newspaper in Italy Begin forwarded message: From: Sarcina Giuseppe Date: May 5, 2020 at 8:03:29 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) Subject: Re: request of intervi ew by Giuseppe Sarcina, corriere della Sera --------=-=--= Inviato da iPhone Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the ital ian case with great attention. I wonder if you can grant me a short inte rview. I have sent an email march 21. But then I saw that you spoke with an other italian newspape r. So I would like to have a chance to have your voice for our Readers as well . Corriere della Sera is a newspaper based in Milano, Lombardy , The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6) Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere della Sera, the main italian newspaper. I understood that you are looking at the italian case with great attention. I wonder if you can grant me a short inte rview . That would be really helpful fo r our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) To: Tue, 5 May 2020 10:43:37 -0400 NIAIDODAM Subject: Fwd: Invitation to Participate in Book Project on COVID-19 L et us discuss. --------------------- (b) (5) Begin forwarded message: From: Dawinder Sidhu Date: May 5, 2020 at 8:14:12 AM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6) Subject: Invitation to Participate in Book Project on COVID-19 -------~~ Dr. Fauci, I hope this email finds you well . I am a professor at the University of Maryl and, an elected term member in the Counci l on Foreign Relations, and a former fellow at the Supreme Court of the Un ited States. I am writing because I am preparing a book, tentatively ent itled "Rebuilding America: A Blueprint for Post-COVID-19 America," consis tin g of essays by leading figures on (1) how COVID-19 has impact ed their particu lar field , and (2) how that field shou ld be reimagined in light of the crisis. The essays will reconsider all sectors of socie ty, includin g law, education, healthcare, fash ion, mus ic, etc. , and collectively will be the first comprehensive guide for post-coronavirus reconstruction efforts. I am very hopeful that you may be willing to contribute a short essay on how the curren t coronavirus has impacted public health policy , and how such policies can and should evolve moving forward. Only 50 industry leaders are being asked to contribute. Commitments have been secured from an impressive group, including a retired four-star general and a preeminent constitutiona l scholar. I very much hope you will take part in this inno vative projec t given you r historic and unparalleled contributions to the public' s understanding of the current crisis. With respect to logistics , I am hoping to receive commitments from all authors this month , with essays due within one month, and with the essays availab le through Amazon's expedited publishing platform rough ly one month after that. Each essay should be no more than 1,000 words , and I may offer light edits for the author's final approva l. A final note: all proceeds from the sa le of the book will be donated. I am very hopeful that you will give eve ry serious cons iderat ion to this invitation, and will lend your voice towards reirnagining and revitalizing a new America. Best, Dave Dawindcr S. Sidhu University of Maryland (b)(6) dss@umbc.edu From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 13:00:29 +0000 Lipkin, Ian W. RE:SARS-CoV-2 Thanks, Ian. I hope that you are we ll. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:--:= From: Lipkin, Ian W Date: Tuesday, May 5, 2020 8:39 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: SARS-CoV-2 (b)(6) --------- (b)(6) Tony, (b)( 4) This prompted the letter I sent to him last evening to which he responded this morn ing. I dont expect a response but wanted to keep you updated. We deeply appreciate your efforts in steering and messaging. Allmy best, Ian Ps . Skell ju st invested $SM in pilot ing the GI DEoN internat io na l capacity bu ild ing and surve illance netwo rk that includes Cliff and others in your intramu ral team . Begin forwarded message : From: Zh uChen Cb)(6)> Subj ect: Re :SARS -CoV-2 Date: May 5, 2020 at 8:16:23 AM EDT To: Lipkin, Ian W . ----------- (b)(6) > Dear Ian, Thank ou for our ema il detailing the (b) (4) (b) (4) -------------------- 4>. I shall keep you informed of any CbH progress in the coming weeks . Best, Zhu ---- ------------- Original ---------------------------~~ From: "Lipkin , Ian W "-~-- - -- -... ~---.-.---------Date: Tue, 5, 2020 06:06 AM To: "ZhuChen t Cb H ~ >; Subj ect: SARS-CoV -2 Ma y Cb _H.... Dear Zhu , The COVI D-19 pandemic poses an unprecedented threat not only to globa l public health but also to economic and political stability . Uncerta inty about the origin of COVID-19 pandemic is caus ing friction worldw ide, particular ly between China and the United States . There is agreement that th e causative agent , SARS -CoV -2 originated in a bat. There is also a high level of confidence that the virus was not deliberately modified in any labo ratory. What we do not know is the answers to two questio ns : (1) whether a precu rsor virus circulated in the human popu lation before it evolved to become a pandem ic virus and 2 whether a recursor virus 4> ada ted to humans by first passing through another animal. CbH (b) (4) With great affection, Ian W. Ian Lipkin, MD John Snow Professor of Epidemiology and Director Center for Infection and Immunity Mailman School of Public Health Professor of Pathology and Neurology College of Physicians & Surgeons Columb ia University 722 West 168th Street, 17th Floor New York, NY 10032 Voice : Cb) (6) Fax: (212) 342-9044 Email: CbH ~ droi oJstrntLveCoo cdinato~ (b)(6) www.cii .columb ia.edu Follow CII on Twitter: CII_Columb ia I Facebook : GIi.Coiumbia Frmn : Date: To: Eiubject: Attachments: Fauci, Anthony {NIH/N IAID) [E) Tue, 5 May 2020 12:40:52 +0000 Barasch, Kimberly {NIH/NIAI D) [C) FW: VP slides VP bri ef VRCSmay2020v2 .pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mascola, John (NIH/VRC) [E] Date: Monday, May 4, 2020 7:07 PM To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: VP slides --------------- (b)(6) --=:= ,.:::::=======6-:= ---------- Tony, here are slides, including changes we discussed. Patty and all have them. John From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 12:06:24 +0000 Harris, Mary (NIH/NIAID) [El RE:Thank you, Dr. Fauci, Thank you so very much ! Mary: Many t hanks fo r you r kind not e. It is much appr eciat ed. St ay we ll. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------------- (b)( > From: Harris, Mary (NIH/NIAID) [El Sen t: Tuesday, May 5, 2020 8:04 AM ~= To: Fauci, Anthony {NIH/NIAID) [El------(b)(6) Subject: Than k you, Dr. Fauci, Than k you so very much ! Dr. Fauci, I wanted to personally thank you for being the voice of reason, security , comfort and insight. (b)(6) As much as I miss bein g in the office, I am grateful to say my Director is Dr. Anthony Fauci and share with my family, friends, and church that if you said it, it's gospel. They can bank on it ! You have given comfort to my family and myself. You will never know how much ! I want you and those who in researchers who are hard at work withou t much rest but tons of sacrifice including that of your fami lies to find a vaccine, give the Natio n a sense of safety and security in this unprecedented time are great ly appreciated. My family, friend and myself are send our prayers for yo ur continued strength. Thank you doesn' t seem like enough . I couldn't be prouder to work at NIAID and specifically on the Simply Grateful, ih floor of Buildi ng 31. Mary Harris NIAID Travel Policy Specialist NIAID Travel Card Coordinator (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [El Tue, 5 May 2020 00:37:21 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: CORONA and BACTERIALSUPERINFECTION Attachments : 1918 influenza insight- fauci.pdf, ESPel arroz epidemol.pdf, Infection and lmmunity-2015-Rynda-Apple-3764.full.pdf, JClinsightco -infection.pdf, lancet.png, Mail Esp.pdf, mai l germany 1.pdf, piramide.png, PLEASEFORWARDTHIS MESSAGETO error.pdf, portugal.pdf, Predomi nant Role of Bacter ial Pneumonia as a Cause of Death in Pandemic Influenza - Dr Fauci.pdf, press usa.pdf, Recuperados.pdf, spanish f lu 1918 - eng original.pdf , tyska pres mail.pdf, US error message.pdf, Us mail 0408 .pdf, WHO-2019-nCoV-clinical-2020.4 -eng.pdf, virus piramdie eng.png Pleas e take a look and decide. Thanks. From: Ola Me lhus (b)( Date: Monday, May 4, 2020 12:25 PM To: (b)(6) (NIH/NIAID) [E] .------------------------- Fauci, Anthony (b)(6) Subject: CORONA and BACTERIALSUPERINFECTION Dear Doctors, I don't know if you have got this infomation. A truly deadly virus cannot spread very far . Why? Because people qu ickly get sick and die. In other words, they cannot spread the virus further , which is a prerequisite for a large spread like corona. Covid-19 has spread throughout the world. The premise is that it is not very dangerous, it causes mild symptoms for most people, many do not even notice that they were sick. But the virus has different phases in the body, after a while it goes into a resting phase, you fee l better, but the virus is still present and can pass on. Covid-19 is an optimally developed virus that spreads rap id ly around the world. But if it were really deadly, almost everyone would die. So far in our 4 billion long history, there have been no airborne viruses or bacteria. Yes, in the hollywood movie "outbreak" there was, but it was a movie. Why hasn't it? If it had existed, this planet would have been a dead planet without life. It would have killed all living. It is possible that there is somewhere else in the universe, but not here on planet Earth. Not now. Remember, this is not the first time a new virus is spreading in the world. What is happening now has happened earlier in our long history . But people are die you say. Yes, but the virus don't kill them . The virus open a "door" in the cell wall thats allows for bacterias, how always are present, to invade the body and create an aggressiv bacterial superinfection. That's what kills them . See, 1. Influenza and Bacterial Superinfection: Disease. Illuminating the Immunologic Mechanisms of Reducedsusceptlbllity (d1y 2-3 post-lAVI Increasedsusceptibility {clay6-7 post•IAV) FIG I Common pathw.!)'S of $umptibilit}'to postinfluenu bacterialsupennfectioru.Earlyafter influenu Virusinfection,miceshow reducedrusccpt.ibilityto supainfection that is at leastin pan due to lncreasedprodurtlon of IL- 13.This IL-I3-ricbem'lronmentdoes not permnIFN•'Yproduction.allo\'oingunaltered phagocytosls md clearance of bacteria. The rol, for either neutropbili. or macrophages (phagocytes) in lnnerbl dearance early dwing lnfluenu virus Infection Im not bttn hillyinvestigated.Progres.sionof inRu,nz:aviTUSinfl'Ctionresullsin increasrosu.1apnbilit)• to secondaryinftction.Typt I IFN (or lL-27)signaling initialedin respo03eto inlluenz.aVirusinftction rer.ultsin downrtgulatedproduction of IL-111 and 11-23and impairedtype 17 immunerespo~. Inhibitionof IL- 17and IL-ll nduces production of antimiaobW peptides. Type I IFN signal ing also reduces levels of neu trophil diemoattr.ict:mts Cxdl and Cxc12md can induce fonnation of NETs.lL-27rnduced during influenza virus infectionfurthersuppresses11..-17 producuon but stimulatesproductionof regulatory cytoklne IL-10,whichcontribwes to increasedsusctptibility to superinfection,presumablyby alterationof lh• anti-influenz;iinflammatoryrt5ponse.IAV, innuenu A virusin~ction. and thi s reports: 2 . Deaths from Bacterial Pneumonia dur ing 1918-19 Influenza Pandemic 3. The 1918 Influenza Pandemic: Insights for the 21st Century 4. Interactions between influenza and bacterial respiratory pathogens : implica t ions for pandemic preparedness 5. Survival duri ng influenza -associated bacterial superinfection improves follow ing viral- and bacterial-spec ific monoclonal antibody treatment 6. Predominant Role of Bacteria l Pneumonia as a Cause of Death in Pandemic Influenza : Implications for Pandemic Influenza Preparedness How can this happen? How can the doctors be so blind . I have a t heory about this and here it comes: My --- CbH6)was a psychologist. May she rest in peace in heaven. It seems that the corona virus has affected the brain more in a certain group in society, name ly politicians, doctors, journalists and other with power and positions in the society. The virus is not dangerous for this group, but it's opens a door in t he brain's cell wall that allows it to enter the fear center of t he brain. This door has been closed for many years. We haven't had any major wars and nothing has threatened them. They have felt invulnerable. Convinced of t heir own superior abil ity and grea t ness. Not only can they cont rol t he people, they can now control the climate by turning the carbon dioxide tap. If they close it, the temperature drops, if they open it the temperature goes up. They don't know tha t the sun is 109 t ime s as big as our planet. 109 times . It seams so small when we look up in the sky. They thought they could cont rol everything. Then came the VIRUS, they receive an abrupt awakening. They get sca red. Polit icans get sick and die. Doctors die. The brain is attacked by fear virus. They can no longer think clearly and logically. The pan ic is near, they are reminded of their own morta lity. Just like a virus in a computer. It's slows it down and it becomes unusable. Tha ts whats happen when a fear virus attacks the brain. Here where I live, there are panic over 1600 confirmed cases. The telev ison is talking "infected persons" when t here is "confirmed laboratory cases". It's two different things. Misleading the people . Why panic over 1 600 infected? Closing all not nessecary bui ssness, all school s, all excep t for supe rmarket, gas station, banks. You can't go out after 5.00 pm. If you do, you get arrested. Why? They are scared. Because the ruling class is afraid. Everyone with this masks. Doctors crying on television. The President with mask. They are scared . Doctors. Journalists. Polices. 2020. The year when the world got completely You have an medical obligation the truth. Kind regards, Ola Melhus crazy. to inform the world about From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [E) Tue, 5 May 2020 00:36:13 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Therapeu tics and vax NIAID SARS-CoV-2Tx and Vax overview.docx Please print out and put in folder labelled "COVID-19 Ther apeutics and Vaccines" From: Marston , Hilary (NIH/NIAID) [E]________ Date: Monday, May 4, 2020 12:32 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Subject: Therapeutics and vax Cb _H_6) (b= H=6)> (b)(6)•>; Barasch, Kimberly {NIH/NIAID) [CJ --------- For your Therapeutics discussion lat er to day From: Date: To: Cc: (b)(6) Mon, 4 May 2020 19:52: 45 -0400 Troye, Olivia EOP/NSC Hurst, Natalie R. EOP/OVP;Mascola, John (NIH/VRC) [E);Graham , Barney (NIH/VRC) [E);Francis Collins Subject: Re: Emai l connecting us Here they are. Thanks On May 4, 2020, at 7:46 PM, Troye, Olivia EOP/NSC (b)(6) Hi Dr. Fauci, Per our conversation, sending you a note. I'm copying Natalie who will he lp get them cleared in . Tha nk you! Olivia Olivia Trove Special Advisor to the Vice President for Homeland Security, Countert errorism, and North America Office of the Vice President, National Security Affairs Whit e House Coronavirus Task Force 0: (b)(6) I M: (b)(6) (Does not receive texts) (b)(6) (bX5) -PCI From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 21:05:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 Please see me about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Monday, May 4, 2020 11:18 AM To: ICDDIR-L@LIST.NIH.GOV Cc: Parker, Ashley (NIH/OD) [E) (b)(6); Whalley, David (FNIH) [T] _, (b)( >; Melencio, Cheryl (FNIH) [T) (b)(6J> Subject: Invitation to join (virtua lly) the ACTIV Leadership Meeting 5/6 ______ Dear Colleagues, As you may be aware, the Accelerating COVID-19 Therape ut ic Interventions and Vaccines (ACTIV) publicpr ivate partnership has been moving forw ard rapidly to address the global pandemic. We held our initial ACTIV leadership meeting on April 3rd including, NIH, FDA, BARDA, EMA, and industry heads of research and development . Four work ing grou ps were formed out of this meeti ng to focus on precli nical therapeutics, clinical therapeutics, clinical trial capacity, and vaccines. Although some ICs have representatives participating in t he working groups, we recognize there is a need to keep everyone looped in to the various activities and prog ress of the partnership, particula rly in view of all of the concurrent IC projects about COVID-19. The ACTIV working groups will be delivering t heir second report to the ACTIV Leadership Group on W ednesday, M ay 6, from 3:30-5:00 pm. I am writing to invite the ICDsto list en-in on this meeting. There will be a lot to cover during the meet ing and th e members of t he Leadership Group will be asking the questions . But to give a chance for us NIHers to discuss what has been presented, I am scheduling a separate ICD call for 5:05-5:30pm, immediately follow ing the ACTIV leadership meeting. If you are available to take part, please send your responses to David Wholley and Cheryl Melencio of FNIH (cc'd here) by noon tomorrow , May 5th . Once you confirm your attendance, Cheryl will send you a calendar invite for both the ACTIV leadership meeting and the ICD follow-up call. Best regards, Francis Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 15:28:08 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Need your help Covid-19 CAS-1O685 From: Date: To: Subject: I do not know this person. We should refer him to Brett Giroir. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, May 4, 2020 10:04 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Need your help Covid-19 CAS-10685 (b)(6) •> -=-:-= (b)(6)> Do you know this person? Patricia L. Conrad Public Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7AO3 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer : The informat ion in this e-mail and any of its attachments is confidentia l and may contain sens itive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: Harris, Kara (NIH/NIAID) [El Date: Friday, May 1, 2020 8:38 AM To: Conrad, Patricia (NIH/NIAID) [El (bH > Cc: Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; Haskins, Melinda (NIH/NIAID) -------Subject: FW: Need your help Covid -19 CAS-10685 >; Billet, Courtney (N IH/NIAID) [El ---------- [El (b)(6) Hi, PattyThis individua l states that he previously worked with Dr. Fauci and that he knows him. Please let me know if you would like Public Inquiries to handle . Thanks, Kara From: Ray Rosa (b)(6)> Date: Thursday , April 30, 2020 5:58 PM To: NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid. nih.gov> Subject: Need your he lp Covid-19 I am working with a group of physicians whom need your guidance on Serum Covid-19 tests. I need someone to call me so I can ask specific questions . I worked with Dr Fauci back in 1998 when I was in the Air Force. So he does know me. Ray Rosa is the name . Can you please call me. (b)(6) cell Scot from AOL Mobile Mail Get the new /\OL app· mail.mobile.aol.com From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Mo n, 4 May 2020 14:00:23 +0000 NIAIDODAM FW: inquiry Anot her one that he will probably want to do. (b)( From: Augustine M. K. Choi Date: Monday, May 4, 2020 9:21 AM ---------- To: Fauci, Anthony {NIH/NIAID) [E] -----Cc: Conrad, Patric ia (NIH/NIAID) [E] Subje ct; inquiry (b =)""'(6J => ---------- (b)( > Hi Tony, I can only imagine your schedule. Thank you for all you are doing for the country in our fight against this virus. Weill Cornell would like to invite you for a 3 min remarks to the Class of 2020 at their upcoming graduation if your schedule allows. The virtual graduation is on May 28th . We can tape your remarks at any time which fits your schedule, from now or up to right befo re May 28. If you able to accept this invitation, please let me know. If not, totally understandable and we would love to have you back again after covid subsides. Thanks again! Augustine M.K. Choi, M.D. Stephen and Suzanne Weiss Dean, Weill Cornell Medicine Provost for Medical Affairs, Cornell University Weill Cornell Medicine 1300 York Avenue, Suite F-113 Box 83 I New York, NY 10065 Telephone: 212-746-6005 Fax: 212 -746 -8424 Email: amc2056@med.cornell.edu From: Anthony Fauc i (b) (6) Date: Monday, March 30, 2020 at 12:19 PM To: Augustine Choi Subject: [EXTERNAL] RE: all wearing masks (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www .coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 4 May 2020 12:28:04 +0000 To: Corey, Larry Subject: FW: [EXTERNAL]RE: OK to contac t Joe Mene t ski to discuss opport unities for alignment/ col laborat ion on ACTIV act ivities ? As an FYI for the 9:00 AM meet ing. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dolsten, Mikael (b)(6)> Date: Monday, May 4, 2020 8:15 AM To: Collins, Francis (NIH/OD) [E] ~ -;:::=====:::::.., ;;-s-r;,= Cc: Fauci, Anthony (NIH/NIAID) [E] >; Mascola, John (NIH/VRC) [E] (b)(6)>; Lane, Cliff (NIH/N IAID) [E) CbH >; Lowy, Douglas (NIH/NCI) ":":"::-::=:======~ ~ [E) (b)(6) ; Jansen, Kathrin (b)( > Subject: Re: [EXTERNAL) RE:OK to contact Joe Menetski t o d iscuss opportunities for alignment/ collaborat ion on ACTIV act ivities? ------~ = Francis Thanks for the response We appreciate the federal initiative and opportunity to influence it's design . I know Kathrin Jansen (ccd here) from PFEis working w the team on t his. ________ ..... (b)(4 ) 4 CbH >It 's great to be collaborating w NIH-FDA for the best of our nation and global health. In the master protocol, I hope the work ing comm ittee is discussing (b) (5) (b)( 5) (b)(5) These are just two exampleswe can discusson Wednesday in the leadership meeting of times permits. (b)(5) I look forward to the meeting Best Mikael Sent from my iPhone On May 4, 2020, at 04:26, Collins,Francis(NIH/OD) [E]______ (b_ H_6)> wrote: Hi Mikael, Wow, sounds like you are making fantastic progress with the vaccine program, and we would certain ly not want to do anything to slow you down! I understand that you are evaluating several mRNA formats with BioNTech. If one of those turned out t o be ready for phase 11/1 11in late June, we would be most interested in the possibility of includ ing that in the master protocol. Please keep Tony and me in touch with Pfizer's progress, including which mRNA format you choose to move into advanced development. Hope to hear your voice at the ACTIVLeadership Group meeting on Wednesday . There will be a lot to ta lk about! Best, Francis Fro m : Dolsten, Mikael (b)(6)> Date: Sunday, May 3, 2020 6:26 PM To: Collins, Francis (NIH/OD) [El (b)( > Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? ------~ = Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b)(4) I will d iscuss w Kathrin Jansen if we may have an option to add one of ou r several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints, we can include that cross all studies Whethe r master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Wor ldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5:16 PM, Collins, Francis (NIH/OD) [El (b)(6)> wrote: Mats -------- Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial with adaptive design, multiple arms , and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be included - might Pfizer also join? 4 CbH>- I trust that compound is ----------------n the list of therapeutic candidates that the Clinical Therapeutics WG 0 of ACTIV is reviewing? They are supposed to put forward a tentative list for the Wednesday Leadership Group meeting. Ditto with the (b)(4 option! Looking forward to catching up soon! Best, Francis -------------------- -== From: Dolsten, Mikael (b)(6) 1> Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis {NIH/OD} [E] (b)( > Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid t imes. In the vaccine space we have progressed rapidly and are already in phase 1/2 studies dose escalation phase testing multiple format of mRNA vaccine . Key for us is (b) (4 . - (b) (4) How are things going w ACTIV. Any issues to discuss ? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] (b) (6)> wrote: Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Wholley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] _____ ----------- (b)(6) --,;Cb ..,.,. H=6) Cc: Dolsten, Mikael (b)(6); Prof Trevor M Jones CBEFMedSci (b)( >; Sogaard, Morten Cb)(6)> Subje ct : OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Francis, I hope you are having a good weekend . Quick question: Would you be OK if I/we reached out to Joe Menetski, who I understand leads many of the ACTIV efforts. We have come to know Joe very well as a great collaborator on the AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportun it ies for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 4 May 2020 10:53:14 +0000 Haskins, Melinda (NIH/NIAID) [El RE: EOP/OMB Alert: May Hearing Guidance What does this mean for the May 12 Senate Hearing? From: Haskins, Melinda (NIH/NIAID) [El (b)(6) Se nt : Monday, May 4, 2020 6:20 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Billet, Courtney {NIH/NIAID) [E] Subject: EOP/OMB Alert: May Hearing Guidance -----~~ (b)(6)> (b)(6)> I have highlighted in yellow the fundaments of the 0MB guidance below. Melinda From: Hallett, Adrienne (NIH/OD) [E] (b)( > Se nt : Sunday, May 3, 2020 9:54 PM To: OD-OLPA-Leg Contacts <00-0LPA-LegContacts@OD .NIH.GOV> Subject: Fwd: May Hearing Guidance FYI. New 0MB hear ing guidance. From: Yaworske, Jason A. EOP/OMB Date: Sunday, May 3, 2020 9:06 PM Cc: Ueland, Eric M . EOP/WHO ( ov p.eop.gov) ------------ (b) (6)> --------~ = __ __;_ __ -=======~~-- (b)(6)>; Hodgson, Christophe r (b)(6) Subject: May Hearing Guidance Importance: High Agency legislative affairs teams, (bX5)-PCI Thank you, and please let us know if you have any questions . Jason Jason Yaworske Associate Director for Legislative Affa irs Office of Management and Budget (b)(6) ( 0) (b)(6) (c) From: Date: To: [El Fauci, Anthony (NIH/NIAID) [E) Mon, 4 May 2020 00:50:18 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) Tabak, Lawrence (NIH/OD) [E];Parker, Ashley (NIH/OD) [E] Subject: RE:[EXTERNAL ] RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Cc: We need to find out precisely what he is ta lking about when he says "vaccine formats" and "refined formats". I really do not know what he is talking about. (b)(4),(b)(5) John/Cliff: Let us discuss this at our morning meet ing . Thanks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Sunday, May 3, 2020 8:03 PM To: Mascola, John (NIH/VRC) [E]______ --,;(b"'""' )( =6); Lane, Cliff (NIH/NIAID) IE] (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Cc: Tabak, Lawrence {NIH/OD) [E) (b)(6J>; Parker, Ashley (NIH/OD) [E) -------- (b)( Subject: FW: [EXTERNAL]RE:OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIV activities? Hi John, Cliff, and Tony , See note below, where Mikael Dolsten indicates Pfizer is planning to 4> CbH . He intends to discuss our master protocol possibility with Kathrin Jensen. am not qu ite sure what he means by "several vaccine formats". Does this timetable sound realist ic? Any suggestion about a response? Francis From: Dolsten, Mikael Date: Sunday, May 3, 2020 6:26 PM -----~~ To: Collins, Francis (NIH/OD) [E] ---------- ------- (b)(6) (b)(6) Subject: Re: [EXTERNAL]RE:OK to contact Joe Menetski to d iscuss opportunities for alignment/ collaboration on ACTIVactivities? Hi Francis We certainly enjoy taking part in ACTIV I will check if we did get our drugs on the lists below (b) (4) I will discuss w Kathrin Jansen if we may have an option to add on e of our several vaccine formats that is less advanced or a refined format of our most advanced in the master protocol etc If we can agree about shared key endpoints , we can include that cross all studies Whether master protocol or more advanced sponsor trials which helps comparison Happy to discuss w you and welcome your advice Mikael Mikael Dolsten, M.D., Ph.D. Chief Scientific Officer and President, Worldwide Research, Development and Medical Pfizer Inc. 235 East 42nd Street New York, NY 10017 On May 3, 2020, at 5 :16 PM, Collins, Francis (NIH/OD) [E] Mats -------- (b)(6) wrote : Hi Mikael, Thanks for your note and this update on exciting progress on several fronts. ACTIV is moving forward with gratifying speed and commitment. With regard to vaccines, tomorrow the ACTIV vaccines WG will be discussing a master protocol for a phase 11/111 trial wi t h adaptive design, multiple arms, and a shared placebo arm, aiming to launch on or about July 1. FDA is strongly supportive. The Moderna, Sanofi, and JnJ vaccines are likely to be inc lud ed - might Pfizer also join? I trust that compound is on the list -----------------f therapeutic candidates that the Clinical Therapeutics WG of ACTIV is reviewing? (b)( 4)- 0 They are supposed to put forward a tentative list for the Wednesday Leadership 4> option! Group meeting. Ditto with the CbH Looking forward to catching up soon! Best, Francis ----------- From: Dolsten, Mikael Date: Sunday, May 3, 2020 12:06 PM To: Collins, Francis (NIH/OD) [E] ______ (b)( .,,. (b""" )(=6) Subject: Re: [EXTERNAL]RE: OK to contact Joe Menetski to discuss opportunities alignment/ collaboration on ACTIV activities? for HI Francis I trust you are well but likely working too many hours as we all experience in the difficult Covid times . (b) (4) (b) (4) How are things going w ACTIV. Any issuesto discuss? I hope our PFErepresentatives in ACTIV are helping out well Pis let me know if there is anything particular to discuss or I can help you with Best personal regards Mikael Sent from my iPhone On May 3, 2020, at 10:49, Collins, Francis (NIH/OD) [E] wrote : -------- (b)(6) Hi Morten, Thanks for your note. It would be great to have this connection - but let me suggest that you start with David Whalley (cc'd here), as he oversees all four of the ACTIV working groups. Joe is the program lead for the group on preclinical therapeutics/repurposing. Best, Francis ----------- From: Sogaard, Morten Date: Sunday, May 3, 2020 10:46 AM To: Collins, Francis (NIH/OD) [E] ------=Cc: Dolsten, Mikael FMedSci ------!=======; (b)(6)> (b)'""(=6)> (b)(6); (b:;:: )(c"= 6);;---- (b)( ; Prof Trevor M Jones CBE Sogaard, Morten Subject: OK to contact Joe Menetski to discuss opportunities for alignment/ collaboration on ACTIVactivities? Francis, I hope you are having a good weekend. Quick question: Would you be OK if I/we reached out to Joe Menetsk i, who I understand leads many of the ACTIVefforts. We have come to know Joe very well as a great collaborator on t he AMP gene therapy initiative and It would be very easy I think working informally with Joe to look a bit more under the hood and identify/ map opportunities for alignment with the other initiatives. All the Best, Morten From: Date: To: Subject: Attachments: 5-08-2020 (videos) .docx Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:45:43 +0000 Greg Folkers (b)( 6) );Doe pel, Laurie (NIH/NIAID) [El Pitt and INC Commenc ement Remark s, generic 30-sec for UPitt and UNC SOM, - FINAL - for See attachment with remarks for UPitt and UNC. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL(tracking needs to be accepted) in the OD folder . Thanks . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21 :28:33 +0000 Greg Folkers (b)(6) ;Doepel, Laurie (NIH/NIAID) [El USUHS Commencement Remark s, USUHS 2-min -FINA L- for 5-16-2020 (Vid eo).docx See attachment with USUHS remarks . I have left the tracked changes showing so that you can see what I have done. Please accept these and then proof it. It is now marked FINAL {tracking needs to be accepted) in t he OD folder . Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 21:21:04 +0000 Greg Folkers (b)(6) );Doe pel, Laurie (NIH/NIAID) [El AMA Commencement Remark s, AMA 3-min - FINAL - fo r May 2020 (Video).docx See attachment with AMA remarks. I have left the tracked changes showing so that you can see what I have done . Please accept these and then proof it. It is now marked FINAL (tracking needs to be accepted) in the OD folder. Thanks. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:58:32 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) UCSF Commencement Remark s, UCSF SOM - FINAL- for May 2020 (Vide o) .do cx ________ .... Greg/Laurie: I am attaching the UCSF3 minute talk. I labeled it as "FINAL" and it is in the OD folder. However, I have left in the tracked changes fo r you to see what I did. Please accept the changes and then go over it one last time . I like it the way it is and so please no trivial corrections. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 20:11:08 +0000 Doepel, Laurie (NIH/ NIAID) [E);Greg Folkers (b)( ) Holy Cross Commenc ement Remark s, Holy Cross - FINAL- for 05-22-2020 (video) .docx The Holy Cross video script is in th e OD File mar ked as " FINAL". I have left the tracked changes showin g so tha t you will know w hat I have do ne. Please accept t he changes and tak e a final look. I am also attaching for your look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 18:34:28 +0000 Tromberg, Bruce (NIH/N IBIB) [E);'Sharpless, Ned From: Date: To: -----------, (b =~=(6)) ' Cc: Subject: Conrad, Patricia (NIH/N IAID) [E) RE:2 quick point s Thanks, Bruce. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Tromberg, Bruce (NIH/NIBIB) [E) Date: Sunday, May 3, 2020 2:28 PM To: Fauci, Anthony (NIH/NIA ID) [E) (b)( 6)> --------, a-s-r,= 'Sharp less, Ned (b)( ; (b)( 6) Cc: Conrad, Patr icia (NIH/NIAID) [E]_______ _ )_ <_ > (b Subject: Re: 2 quick points Hi Tony, Thanks! Hope you are doing well. This is basically exactly wha t we are working to facilitate wit h our RADx and digita l health (app) platform initiatives ...greatly expanding test ing and creating a digita l backbone to provide peopl e with way s to access tests and interpret results . For expanding test ing platforms, see https://www.nibib .nih.gov/news events/newsroorn/nih-mobil izes-national -innovation -initiative -covid-19-diagnostics We have > 700 applicat ions that have been started in just a few days. For the digital healt h (e.g. app) platform we 've put a lot of thought into the design and are hoping a contractor wil l be able to launch a pilot st udy of healthcare workers soon . Ned and I plan on issuing additional calls in this area w ith mul tiple institute s as stakeho lders in t he coming weeks. Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih .gov From: "Fauc i, Anthony (NIH/ N IAID) [E]" < (b)(6) --------Date: Sunday, May 3, 2020 at 1:55 PM To: "'Sharpless, Ned --------------------------~~ ~~~":""":"'.~========~;-----------Tro m berg, Bruce (NIH/N IBIB) [E]" ~-=========~ Cc: "Conrad , Patric ia (NIH/NIAID) [E]" ________ Cb _H_6J (b)(6) (b)(6)> 11 Subje ct : FW: 2 quick points Ned/ Bruce: I t hought that I w ou ld pass thi s on to you in case yo u have int erest. Thanks. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2 quick points (b)(6)> ------~~ -------- Dear Tony, (b)( > l. I had planned to wr ite to thank you for giving an interview (b)(6)for the Washingt on Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. was waiting for the chaos around you to subside before writing but... .. 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b) (6) As his email says, (b)(6) with Samsung's venture capital group, which has an idea for a future , comprehensive surveillance system for COVID-19 (b)(4) It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-orien t ed individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out Cb)< _ , and certainly nothing is more important these days t han COVID-19 and the outstanding wor k you are doing to manage it . All the very best, -Eric From: Warren, John [ma ilto Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren ------------ (b)(6)] Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bring at least the two of us together. -------- (b)(6)but I'm writing ------ (b)(6)Samsung'sventure capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has ident ified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optimal ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Sun, 3 May 2020 17 :56:39 +0000 NIAIDODAM RE:Dr. Antho ny Fauci & Avi Schiffm an/The Webby Awards From: Date: To: Subject: ????? Who is this person? Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------- From: Auchincloss , Hugh (N IH/NIAID) [El (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [El Date: Sunday, May 3, 2020 1:55 PM To: NIAID OD AM Subject: FW: Dr. Anthony Fauci & Avi Schiffman/T he Webby Awards From: lesley lesleycahillroy.com Date: Friday, May 1, 2020 12:13 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Dr. Anthony Fauci & Avi Schiffman/The Webby Awards HI Dr Fauci I just wa nted to follow up on below regarding Avi and The Webby Awards. Would be wo nderful if you cou ld be a part of this moment for him. Thanks so much Lesley On Apr 20, 2020, at 1:57 PM, lesley lesleycahillroy.com wrote : <6EDD370A-6106-4603-B557-7AAEE9A9EF79.png> Dear Dr. Fauci, I hope you and th e family are all safe and healthy dur ing these challenging times. Hailed by The New York Times as "the Internet's highest honor," The Web by Awards has been t he premiere award for on line excellence for over two decades, honor ing the companies and people who have crit ically shaped digital techno logy and culture. This year, due to the impact of the coronavirus The Web by Awards are mov ing their renowned award show to an onli ne experience. On May 19th, 2020, the 24th Annual Webby Awar ds wi ll bring together Webby Winners from around the world in an Int ernet Celebration whic h wi ll showcase t he artists, organi zations, and creators using th eir platforms to imagine a bette r tomorrow th rough informa t ion, educatio n, movemen t, comedy, all while inspiring audiences to take action to enact posit ive change. The 24th Annual Webby Awa rds are proud to honor Avi Schiffmann as the 2020 Person of the Year to recognize his creation of ncov2019.liv e to track the spread of COVID-19 across the world. W e would be honored if Dr. Fauci would "virtually" present Avi with his award . As we collectively navigate the severe impact of COVID-19 on the world and late calls for nation-wide social distancing, the Internet has become the lifeblood for people looking for accurate information about the novel coronavirus. Since launching the site on December 29th , Avi Schiffmann's tracking site was a necessary tool that sounded the alarm on the novel coronavirus and its spread, notably calling attention to its severity long before many global officials. By providing over 100 million visitors with real-time data on the virus' spread, Schiffmann has helped people around the globe understand COVID-19 and the necessity of upgrades to current health care systems and mea sures to flatten the curve. For having the fore sight to track the global spread of COVID-19 and for creating a website to provide real-time data about the virus to people everywhere, it is our great privilege to honor Avi Schiffmann as the 2020 Webby Person of the Year. The celebration will highlight the important work Avi and his fellow winners are doing, and will mark his hallmark Webby 5-Word acceptance speech in Int ernet history. Dr. Fauci's presenter speech could be recorded on his phone and we can send you through a script for him to review, edit and details for format and deadline. This year's Webby Aw ards w ill also take action, t he impact of COVID-19 and govern ment responses around the world, has brought the importance of vot ing into sharp focus. The Webby Awards has partnered with Vote.or and aim to check the voter registration status of 1 million voters in the United States, promoting the importance of voting to help ensure vote r turnout this November is the highest it has ever been. This partnership will integrate into all elements of this year's on line celebration. Our thoughts are with all of you in this difficult time. Best Lesley Cahill Roy (b)(6) From: Date: To: (NIH/N IBIB) [El Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:55:14 +0000 'Sharpless,Ned Cc: Conrad, Patricia (NIH/NIAID) [E) FW: 2 quick points covid contact tracing.pdf ------------ Subject: Attachments : (b)(6)';Tromberg, Bruce Ned/ Bruce: I thou ght that I wou ld pass thi s on to you in case you have int erest . Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen (b)(6) Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Ant hony (NIH/ NIAID) [E]_______ Subject: 2 quick points ------~~ Cb _H_ > Dear Tony, 1. I had planned to wr ite to thank you for giving an interview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it. I was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says (b)(6) Samsung'sventure capital group, which has an idea for a future, comprehensive surveillance system for COVID-19 (b)( 4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time (b)(6) to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric From: Warren, John [ma ilto ----------- (b)(6) Date: Thursday, April 30, 2020 6:52 PM To: (b)(6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us fro m meeting up because it might yet bri ng at least the two of us together. -------- (b)( ut I'm writing (b)(6)Samsung'sventure capital group and his team has what I th ink is an incredibly useful idea -----for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment t o him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on th e optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MD 21201 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 3 May 2020 17:53:55 +0000 Eric Otte sen RE:2 quick points Eric: Thanks for your note . No problem . I will forward this to people here at NIH who are pursuing such approaches. I hope that all is well with you. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Eric Ottesen Date: Saturday, May 2, 2020 8:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: 2 qu ick points (b)( > -------~~ --------- (b)(6) Dear Tony, 1. I had planned to write to thank you for giving an inte rview for the Washington Post last month. Your generosity with time was 'all Tony,' and I did appreciate it . was waiting for the chaos around you to subside before writing but ..... 2. Last evening I was asked to forward the message below to you. You might already know Jack Warren, Professor of Medicine and Infectious Diseasesat U. Maryland (b)(6) As his email says, (b)(6) Samsung's venture capital group, whic h has an idea for a future, comprehensive surveillance system for COVID-19 (b)(4) . It is interesting, but all I know is what I read in the power-point attached. I cannot imagine you would have time to look at it yourself, but perhaps it could be shared with other systems-oriented individuals working towards 'opening up' responsibly. (b)(6) Pardon me for stepping out of my normal NTD 'swim lane' but I did want to help out (b)~ _ , and certainly nothing is more important these days than COVID-19 and the outstanding work you are doing to manage it. All the very best, -Eric l=rom : Warren , John [ma ilta ----------Date: Thursday, April 30, 2020 6:52 PM To: (b)(6)] (b) (6) Subject: Jack Warren Eric A voice from the past. Covid-19 prevented us from meeting up because it might yet bri ng at least the two of us together. ------- (b)(6l b ut I' m writing .. ----- (b)(6) Samsung's venture capital group and his team has what I think is an incredibly useful idea for contact tracing for covid-19 as well as actually open ing the economy up again. The idea is contained within the attachment. I wonder if you still have any contacts with Anthony Fauci. Is so, could you see your way clear to forwarding the attachment to him? The group has identified some appropriate test manufacturers but is at the point where they need to know the spectrum so as to focus on the optima l ones. The thought was that Tony Fauci might be the best person to know what tests are in development stage. What are your thoughts? Don't worry about confidentiality; they want to widely share this idea so as to get it out as quickly as possible. Thanks Jack Warren MD Professor of Medicine Division of Infect ious Diseases University of Maryland School of Medicine Baltimore MO 21201 (b)(6) From: Date: To: Subject: Impo rt ance: Auch incloss, Hugh (NIH/NIAID) [E] on beh alf of Fau.ci, Ant hony (NIH/ NIAID) [E] Sun, 3 May 2020 17 :52:37 +0000 NIAIDODAM FW: INVITE- Ame rican College of Cardiolog y High From: Kim, Jonathan Ho-Youn (b)(6) Date: Friday, May 1, 20 20 3:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc; Ryan Meye r (b)(6) Roby n Snyde Subject: Re: INVITE- American College of Cardiology ------ ..,.....,..-= (b)(6) ------- (b)(6) Importance: High Dr. Fauci- Of course, I appreciate how busy you are, so just reaching out again on behalf of the American College of Cardiology as noted below. We were hopeful we could steal just an hour of your t ime in June for an important discussion on COVID-19 and exercise training. This is part of a virtual agenda for one of our national conferences (Care of the Athletic Heart) with outreach around the world given this is a part of the ACC educational platform. We hope th is is something you have the bandwidth for, and simply apprec iate your consideration. I hope to hear from you and thank you for all your service once again. My best, Jonathan Kim Jonathan H. Kim MD, MSc, FACC Chief of Sports Cardiology Department of Medicine, Division of Cardiology Department of Orthopedics Emory University Adju nct Assistant Professor Division of Applied Physiology Georgia Inst itute of Technology Team Cardiologist for Emory Athlet ics, Georgia Tech Athletics , Atlanta Falcons, Atlanta Hawks, Atlanta Braves, and Atlanta Dream Office Phone: Cb)(6) Research Profile: http: // medicine .emorv .edu/cardiology/emory-first- facultydjrectory/profi le.htmi?f=JKIM10 Email Cb)(6) From: Kim, Jonathan Ho-Youn Date: Thursday, April 16, 2020 3:46 PM To: (b)(6) Cc: ----======;----RyanMeyer Cb)(·>; RobynSnyder_____ Cb _>_<_,> Subject: INVITE- American Collegeof Cardiology Dr. FauciOn behalf of the American College of Cardiology (ACC), first I would like to thank you for your tremendous service throughout your incredible career and certainly during these present and challenging times. We are indebted to your service and thankful everyday we have you to help guide public health measures through the COVID-19 pandemic . I am a member of the Sports and Exercise Council for the ACC and the Course Chair for our annual ACC Care of the Athletic Heart Conference. Originally scheduled June 18-20, 2020 at ACC Heart House in Washington DC. I am also faculty at Emory University and direct our sports cardiology program in Atlanta. Of course, we have made the difficult decision to cancel our live meeting in June, but myself along with the staff at ACC are working very hard transitioning the course to a virtual course and agenda. This course will be a much shorter version and the agenda w ill all be pre-recorded and distributed as a 'live simulated version' on June 20, 2020. With the impact of COVID-19 on all aspects of life and society, in our academic world of sports cardiology, we are dealing with how COVID has impacted exercise and athletes. As you can imagine, there are a multitude of different issues and questions that colleagues are raising. One new session for our virtual agenda that we think will generate a lot of interest and is of high importance will be a panel discussion on sports, exercise, and COVID-19. We would like to get additional expertise on the panel from the ID/pub lic health and Sports Medic ine arenas, in addition to sports cardiology. Of course, there is no one that carries the expertise you do from t he ID and publ ic health perspective and we would be extremely honored if you could be a part of this one session and join our faculty for the course. Before getting into more details and a formal invite from the ACC, I wanted to first see if you had the bandwidth for this. Understanding you are as busy, if not busier, than anyone in the world right now. This session would be pre-recorded and we would certainly work to be flexible with anytime you had for this in early June to record. I hope this is something that could work- again we would be honored to host you virtually. Many thanks for considering, and hope to hear from you soon. Best, Jonathan Kim Jonathan H. Kim MD, MSc,FACC Chief of Sports Cardiology Departmentof Medicine,Divisionof Cardiology Departmentof Orthopedics Emory University Adjunct AssistantProfessor Divisionof Applied Physiology GeorgiaInstitute of Technology Team Cardiologistfor EmoryAthletics, GeorgiaTech Athletics, Atlanta Falcons,Atlanta Hawks,Atlanta Braves,and Atlanta Dream Office Phone: (b) (6) ResearchProfile: http://medicine.emory.edu/cardiology/emory-first-fac ultydirectory/profile.html?f=JKIM1O Email (b) (6) This e-mail message (including any attachments) is 'or the sole use of lhe intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the Intended recipient, you are hereby notified that any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 3 May 2020 17:50:45 +0000 Jon LaPook RE:Today's segment on CBSSunday Morning Jon: Tenific piece on ":No time to abandon science"! Keep up this great work . We need to stay on course. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and lofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E- mail: (b) (6) The informa1ion in this e-mail and any of its a1tachmen1sis confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbo x or any other storage devices. The National Institute of Allergy and Infectiou s Disease s (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Jon LaPook.-----(b =)..., -= (6) .,,, Date: Sunday, May 3, 2020 I :31 PM (b)(6) > To: Fauci, Anthony (NIH/NlAfD) [E)...,.._,.-,---,----Subject: Today's segment on CBS Sunday Morning Dear Tony, l hope (though would not bet my life that) you are getting at least a modicum of down time today. Here's a Iink to the segment l told you about. No commercial! htt:ps://www .youtube.com /watch?v-OjCohlBICgO [http://img.y outube.com /vi/OjCohlBICgO/O.jpg] Dr. Jon LaPook: No time to abandon science - YouTube www.youtube.com As we reach a point in the COVID-19 pandemic when some states are tempted to open sooner than health experts say they should, Dr. Jon LaPook notes thatthis ... Jon Jonathan LaPook, M.D. Chief Medical Correspondent, CBS Even ing News Professor of Medici ne NYU Langone Health (bXS) - PCP. (bX5) -PCI From: Date: To: Cc: Subject: Fauci, Anthony {NIH/N IAID) [E] Sun, 3 May 2020 17:23 :12 +0000 Paola Dama Conrad , Patricia (NIH/N IA ID) [E) RE: White House Coronav irus Task Force Dr. Dama : Thank you for your note. I am attaching a slide of the members of the USA Task Force and as you can see, Dr. Antonio Gio rdano is not a member. Best regards, A.S. Fauci White House Coronavirus Task Force Announced Jan. 29, 2020 Chair: VP Mike Pence Response Coordinator: Deborah Birx ■ Jerome Adams ■ Stephen Hahn ■ ■ Derek Kan ■ Alex Azar Stephen Biegun ■ Larry Kudlow ■ Robert Bla ir ■ Ch ris Liddell ■ Ben Carson ■ Steven Mnuch ln ■ ■ ■ Ken Cuccinelli Kelvin Oroegeme ier ■ Robert O'Brien Matthew Pott inger ■ Anthony Fauci ■ Robert Redfi eld ■ ■ Joe Grogan ■ Joel Szabat ■ Seema Verma Robert Wllkle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fro m : Paola Dama (b)(6)> Se nt : Sunday, May 3, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: White House Coronavirus Task Force Dear Dr. Fauci, I hope to find you well with this ema il. I take the liberty to write you because I have some concern about the misinformation that can discredit you r task and honors. On many occasions in tv and press, Antonio Giordano , Director of Sbarra Institute in Philadelphia, Keeps saying that he is a member of the USATask Force. I'm wondering if it's true. I work in UK, but I'm originally from Naples (Italy). I he ld my PhD in Carlo Croce's lab at OSU and I specialized in immunotherapy Currently I'm a research fellow at University of Sussex. at University of Chicago. I apologize if you find this email inopportune, the time is unfortunate, I grant you . I don't like t he idea that some people might take advantage of this very unpleasant moment for all the world. So I wish that I made a mistake this time. I'm also wondering if you are willing to release a brief in te rview. I stand with you and USA that I miss very much I really appreciate your time Thank you Kind Regards Ciao O Paola Dama, Ph D Molecula r Oncology and Pharmacology Universityof Sussex School of Life Sciences John Maynard Smith (JMS) Building Room 4B13 Falmer, Brighton BNl 9QG -------Email: Skype : (b)(6) ----- (b)(6) website www .taskforcepandora .com (b)(6) (USA) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 15:44:23 +0000 (b)( 6) Subject: Great phot o of Mommy and me in this article https://ww w. usatoday.com/story/ne ws/nation/2020/05/03/coronavirus-white-house -expert -dr- anthony-fauci-americans-trust/3042991 001/ Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) (b)( 6) FAX:(301) 4 6~09 E-mail: .__....,.,___ (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please info r m the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) Sun, 3 May 2020 10:30:04 -0400 To: Collins, Francis (NIH/OD) [E) Cc: Mascola, John (NIH/VRC) [E);Lane, Cliff (NIH/NIAID) [E);Wholley, David (FNIH) [Tl;Tabak, Lawrence (NIH/OD) [El;Denny, Joshua (NIH/OD) [E);Gebo, Kelly (NIH/OD) [Gl;lowy, Douglas (NIH/NCI) [El;Devaney, Stephanie (NIH/OD) [E];Adam, Stacey (FNIH) [T);Santos, Michael (FNIH) [T];Freire, Maria (FNIH) [T) Subject: Re: crazy idea (b) (5) On May 3, 2020, at 9 :47 AM, Collins, Francis (NIH/OD) [E] (b) (6) >wro te: Hi John, Cliff, and Tony, As we contemplate ways to stand up a master protocol that could enroll 50 - lOOK part icipants in a multi-arm COVID-19 trial th is summer, I wondered if (b)(5) --------------------- See below you think? (b) <5 . Francis From: Denny, Joshua (NIH/OD) [El Date: Saturday, May 2, 2020 11:22 PM To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [El Subject: Re: crazy idea (b)(6)> -------- -----~~ (b)(6) --------- (b)(6)> Hi Francis, This is exciting to hear! Fabulous to hear we may be approaching such a trial. What do (b)(5) Best, Josh Sent from my iPhone On May 2, 2020, at 8:34 PM, Collins, Francis (NIH/OD) [E] ------- (b) (6J>wrote: Hi Josh, - (b) (5l Francis From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 12:31:13 +0000 Handley, Gray (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE:form Jorge Pere z IPK Cuba Thanks. From: Handley , Gray {NIH/NIAID) [E] ________ Date: Saturd ay, May 2, 2020 11:04 PM To: Fauci, Anthony {NIH/NIAID) [El -------:aCc: Conrad, Patricia (NIH/NIAID) [El Subject: RE:form Jorge Perez IPK Cuba Cb _H_ (b.,.... H=6J> (b)(6)•> --------- Will send a reply tomorrow morn ing. I have spoken to State Department and have approved response . Someone w ill listen in. Will copy you. Gray From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, May 2, 2020 3:18 PM To: Handley, Gray {NIH/NIAID) [El Cc: Conrad, Patricia {NIH/NIAID) [El Subject: FW: form Jorge Perez IPK Cuba -------- (b) (6Jr> -------'='"'""'= --------- Gray: Wou ld you please handle this . Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Perez Avila, Jorge (b)(6) Date: Friday, May 1, 2020 12:13 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Subject: form Jorge Perez IPK Cuba ------~~ Cb> _C_6)> Dear Dr. Fauci Hello from Cuba. Have been a long time we haven't been in touch. Now the whole world is facing a new epidemic and in Cuba we are working in order to controling. We will like to re-new our contact regarding this disease Covid 19, we prepare a telephone conference in order to exchange ideas to have a better understanding to control the epidemic. This conference will be held from Cuba next tuerday 05/05/2020 at 4 :30pm Cuban time. In douse I am sending the topics. We will like to have you and Dr. Handle y in th is activity if it is possible to attend this conference. If you are in agreement we will like to know by answering this email and them we will you any other detail. If you have any other person to contac t in order to participate will be helpful! for us. Waiting for your answer. Dr. Jorge Perez IPK Cuba Preliminary program Objectives: Updating COVID-19 situation at global , regional and mainly in Cuba and USA To sharing data of how our two countries are facing this emergency including research studies , etc Topics for the discussion: • The main strategies that both countries are developing to face COVID-19 . • Diagnostic strategy • Clinical management in adults and children • Innovative Cuban biotechnology products incorporated into the treatment models used in the different stages of treatment • Some other research studies • Discussion Events and courses at the following address : http://instituciones.sld.cu/ipk/ To: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 20:17 :31 +0000 Cassetti, Cristina (NIH/NIAID) [El Subject: RE: From: Date: Thanks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Cassetti, Cristina (NIH/NIAID) [E] Date: Saturday, May 2, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Erbelding, Emily (NIH/NIAID) [E] --------= ~ (b)(6) (b)(6)> ~======:=:!~= Conrad, Patr icia (NIH/N IAID) [El ---------(b)(6)>; Subject: RE: Hi, I already reached out to Dr. Bolognesi and some of us in Program have a call scheduled with him to discuss th is propos al. I will let you know t he outcome. Kind regards, Cristina From: Fauci, Anthony (NIH/NIAID) [El Se nt: Saturday, May 2, 2020 3:39 PM To: Cassetti, Cristina {NIH/NIAID) [E] Cc: Erbelding, Emily {NIH/NIAID) [El (b)(6)) -------~~ ';========~CbH6>1; ~ Conrad, Patricia (NIH/N IAID) [E] __________ (b)(6) Subj ect: RE: Import ance: High (b)(6)> , Cristina: It would be a good idea for you to show this to a couple of other NIAID people for their opinion, and then out of courtesy to get back to Dr. Bolognesi one way or another. Thanks, Tony Anthony S . Fauci, MD Direc tor National Institute of Alle rgy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confiden t ial and may contain sens itive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represen tatives. From: Cassetti, Crist ina (NIH/NIAID) (E] Date: Thursday , April 30, 2020 11:36 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Cc: Erbelding, Emily (NIH/NIAID) [E) Subject: RE: (b)( > (b =)""'(6) => --------- (b)(6)> Dear Dr. Fauci, I reviewed this proposal (b)(5) (b)(5). (b)(4) (b) (5), (b) (4l informative ------------------------------to discuss the project directly with them. Wou ld you like for me to put together a small group at NIAID (b)(5) (w ith reps from DMID and DAIDS)to talk with Dr. Bolognesi and his colleagues? Kind regards, Cristina -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM To: Cassetti, Cristina (NIH/NIAID) [E] (b)(6) --------=-=-= ..!=======~~ Cc: Erbelding, Emily (NIH/NIAID) [E] (b)(6) (b)(6)> Subject: FW: Importanc e: High Cristina : Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ AIDS investigators from a few years back . He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: ------~~ Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b) (6)> On Behalf Of (b)(6) Fauci, Anthony ---------------~~ From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/ NIAID) [E] ______ (b)(6) Cb _)_(6J _ >; Barasch, Kimberly (NIH/NIAID) [C] (b)(6) Subje ct: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, wecould arrange a WebEx as an initial step. Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D ." Date: Monday, April 27, 2020 at 2:53 PM ----------"Matthias Gromeier, M .D." -----------~ Subject: Please review this draft-----------email to Tony--TX (b)(6) To: (b)( > Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The in formation in this electron ic mail is sensitive, pro t ected inform ation int ended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electr onic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared un less in compliance with Duke Health policies on confidentiality and/or with the approva l of the sender. Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 19:08:58 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Validated precise prediction of remdesivir's clinical efficacy on SARS-CoV-2 From: Date: To: Subject: viral load Please take a look at this and respond if appropriate. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: ldonae Lovetrue Date: Friday, May 1, 2020 2 :25 PM (b)(6)> ------~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Beigel, John (NIH) [E] (b)(6)> Cb H ; Booth, Mason (NIH/NIAID) [C] Kim, Sonnie (NIH/NIAID) [E] (b)(6) Subject: Validated precise prediction of remdesivir's clinical effi cacy on SARS-CoV-2viral load --------- (b)(6) Dear Dr . Fauc i, I'd like to share with you that the recent clinical trial results on remdesivir have validated our prediction of the remdesivir-specific post -treatment viral rebound in human COVID - 19 pat ients. More details can be found in our off icial announcement https ://b it. ly/RRemdesivir. This prediction of remdesivir's clinical efficacy on viral load made on Fe b. 23 2020 (b) (4) (b)(4) (b) (4) We appreciate and respectall the effortsyourhave made towardsthe COVID-19 pandemic. Bestregards, ldonae ldonae Lovetrue I CEO, Demiurge TechnologiesAG, Switzerland www.demiurge.technology This email and any attachments thereto may contain private, confidential. and privileged material for the sole use of the intended recipient. Any reV1ew,copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and pe, manently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposes only and is provided without any warranty of any kind, either expres1edor implied. While some mformat1on used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees 1t5ac..cur"cy01 completene55 nor accepts liability for any direct or comequential lo5se5arning from its use.Thank you From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 19:00 :06 +0000 Fetalvo, Ninio J. EOP/OVP RE:Back to CMS Ninio: Thank s for all your good work in th e White House . Stay safe and well. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. ----------- From: Fetalvo, Ninio J. EOP/OVP Date: Friday, May 1, 2020 3:12 PM To: (b)(6); Fetalvo, Ninio (CMS/OC} Subject: Back to CMS (b)( ----------- (b)(6) All, Today is my last day on detail to the Office of the Vice President. I am heading back to CMS to cont inue supporting the Trump Adm inistration's response to the coronavirus . It has been an incredible hono r serving the Vice President and the Coronavirus Task Force, and a pleasure working alongside all of you . I look forward to our o ngoing work together . Best, Ninio Ninio J.H. Fetalvo Personal: -----CMS: ________ (b ~)-(6) ~ I Cb _~_C6)I ___ Cb)(6) Cb _~_C6) _ From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 2 May 2020 18:27 :23 +0000 To: Johnson, M artin S. (NIH/NIAID) [E];Auchincloss . Hugh (NIH/ NIAID) [E];NIAID OCGRLeg;McGowan, John J. (NIH/NIAID) [E];Erbelding, Emily (NIH/NIA ID) {E];tane-, Cliff (NIH/N IAID) [E];Rotrosen, Daniel (NIH/N IAID) [E];Crum, Wayne (NIH/NIAID) [El ;Harper, Jill (NIH/NIAID) [El Cc: Eisinger, Robert (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Mar ston, Hilary (NI H/ NIAID) [El;Lerner, Andrea (NIH/N IAID) [E];Doepel, Laurie (N IH/NIAID) [El;Gilles, Sharon (NIH/NIAID ) [E];Routh, Jennifer (NIH/N IAID) [E];Stover, Kathy (NIH/NIAID) [E];Law, Kim (NIH/NIAID) [E]; Lee, Kun- Lin (NIH/NIAID) [E];Bushar, Nicholas (NIH/NIAID) [E];Schneider, Johanna (N IH/NIAID) [El Subject: RE: FY2020 - COVID-19 - Actua l and Forecasted Spending - W eekly Report Ending 4/24/ 20 Thanks , Mart in . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johnson, Martin S. (NIH/NIAID) [E] ________ Cb _> _C6) _ Date: Friday, May 1, 2020 7:40 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= (b)( ; Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> ; NIAID OCGRLeg ; M cGowan, John J. ":'--.-~""."""'.~====-..;._-_,,,:-=\ (NIH/ NIAID) [El _.:....._....:_:~==:e=,:;-----~--- (b)( >; Erbeld ing, Emily (NIH/NIAID} [El --:--"""".'"":"""'.":== (b =)=( 6) =-> ...: ;_L_a_ ne ...: ,_c_1i"" ff~( N = IH/ NIAID) [El (b)( ·; Rotro sen, Daniel (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El ; Harper, Jill (NIH/NIAID) [El (b)( > Cc: Eisinger, Robert {NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/ NIAID) [El (b)(6)>; Lerner, Andrea (NIH/N IAID) IE] Cb)( Doepel, Laurie (NIH/NIAID) [El CbH6)>;Gilles, Sharon (NIH/N IAID) [El Cb)( >; Routh, Jennifer (NIH/NIAID ) [El CbH6)> ; Stover , Kathy (NIH/NIAID) [El (b)(6}; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin ======e:="':;----' (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas {NIH/NIAID) [El (b)(6)v>; --------- Schneider, Johanna (NIH/NIAID) [E] (b)( Subject: RE: FY2020 - COVI0-19 -Actual and Forecasted Spending - Weekly Report Ending 4/24/20 Tony, YTD spending is $110.8M, increasing $24.lM from last wee k. Spending driven by implementation of3 epidemiological studies, ramp up of resources necessary for vaccine candidate testing and vaccine candidate development. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 24, 2020 7:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( >; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRLeg ; McGowan, John J. --:-:-:--.:-:-:-:-:-::-:--:-::".:.::::::====-.;._--. ~ (NIH/NIAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel --.--~~===:.:....._..:..__.;___..;, (NIH/NIAID) [E] (bH6l>; Crum, Wayne (NIH/NIAID) [E] (b)(6); Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon ------~~==:!....:.,. _ _;_...:.....~ (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6)> ; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicho las (NIH/NIAID) [El (b)(6J> ; Schneider, Johanna (NIH/NIAID) [E) (bH ,> Subject: FY 2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 4/24/20 --------=-:~ ---------Tony, YTD spending is $86 .7M , an increase of $8.3M from last week. Spending driven by foundat ional research including the characterizat ion of factors associated with severe disease, transmission dynamics, structural analysis of SARS-CoV-2 proteins . Small awards to support vaccine and therapeutic discovery. Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, April 17, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( ; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID OCGRLeg ; McGowan, John J. "":"--.----:-:--.:.::::::====:;._---, ~ {NIH/NIAID) (El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> ; Lane, Cliff {NIH/NIAID) [E] (b)(6); Rotrosen, Daniel ------~~ -------- (NIH/NIAID) [El (bH6l>; Crum, Wayne (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [El (b)(6); Doepel, Laurie (NIH/NIAID) [E] (b)(6); Gilles, Sharon ":"--.--.-:-.:-::====:...-_;_~~ (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [E] (b)(6); Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [El (b)(6)> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/17 /20 ---------Tony, YTD spending is $78.4M, an increase of $10.9M from last week including costs to evaluate the rapeutics in humans and NHPs, manufacture of a protype virus-like vaccine candidate developed by Taubenberger/Memoli, and spending to accelerate discovery of new therapeutics , vaccines and diagnostics . (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Se nt : Friday, April 10, 2020 8:22 PM ------~~ (b)( >; Auchincloss, Hugh (NIH/NIAID) [El NIAID OCGRLeg ; McGowan, John J. ..... -.----:-:-:-:-:;:::=====~--~~ (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>; (b)(6); CbH6) 1 >; Lane, Cliff (NIH/NIAID) [El Cb)( >; Rotrosen, Daniel (NIH/NIAID) [El CbH6); Crum, Wayne (NIH/NIAID) [El CbH6); Harper, Jill (NIH/NIAID) [E) (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6)::>; Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) Stover, Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [El (b)(6); Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 4/10/20 ":":""'-.-:-:-:----:-:-::--:;::::::="="".!_ ---------Tony, YTD spending is $67 .SM, unchanged* from last week . A summary is attached . I have also attached an updated budget plan reflecting our projected spending by research category by fiscal year. We are updating this weekly as we receive updates from the divisions on the timing of clinical trials, observat ional studies, natural history studies and research resource needs. We w ill report mid-week on our YTD spending which will be in sync with the data the Dept. extracts. Martin • The reason that we have reported no weekly increase is to match our reported spending with the financial information that the Department is now extracting from our accounting system. We have always included spending from our regular appropriat ion, as directed by the Department. Now the guidance from the Dept. has been updated to report only spending from the supplemental COVID19 appropriations. From: Johnson, Martin S. (NIH/NIAID) (E] Date: Friday, April 3, 2020 8 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] ,r------- =)- c='>; Auch incloss, Hugh (NIH/NIAID) [E] (b (b)(6J>;NIAID 0CGR Leg ; McGowan, John J. (b)( >; Erbelding, Emily (NIH/NIAID) [E] CbH6J> ; Lane, Cliff (NIH/NIAID) [E] CbH6J>; Rotrosen, Daniel (NIH/NIAID) [E] (b)(6l>; Crum , Wayne (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIAID) [E] (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El CbH >; Folkers, Greg (N IH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6J>; Marston, Hilary (NIH/NIAID) [E] CbH6l>;Lerner, Andrea (NIH/NIAID) [El (b)(6)>; Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon "".". (N ""'." l"."". H-:'. /N""'." l""'." A~ID'."'."' )":". [E ~]===..:....-:..,_ :::(b.,.., )(= >; Routh, Jennifer (NIH/NIAID) [E] (b)(6); ":":'"'."."."'.'"':"."".".""'."".":"":"7:":'--.:====::::....;.---::-,~ (NIH/NIAID) [E] Stover, Kathy (NIH/NIAID) [E] (b)(6)>; law, Kim (NIH/NIAID) [E] (b)(6); lee, Kun-Lin (NIH/NIAID) [E] (b)(6)>; Bushar, Nicho las (NIH/NIAID) [E] CbH6J ; Schneider, Johanna (NIH/NIAID) [E) CbH ,> Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 4/3/20 --------Tony, YTD spending is $67.SM, a weekly increase of $45 .9M mostly for initial fund ing for set-up of clinical tria ls for eva luat i.on ofremdesivir in patients with ear ly disea se stage and a placebocontrolled clinical trial of intravenous hyperimmune immunoglobu lin (IVIG) in patients with COVID-1.9. I've provided a summary spending plan the team worked on and a table for the $ l .532B that we have received in supplemental appropriations • $82 6M NIAID received 3/5/20 - the Coronavirus Preparedness and Response Supplemental Appropriation s Act • $706M NIAID received 3/25/20 - the Coronavirus A id, Relief , and. Economic Security (CARES) Act In the last document I've also included narrative summarizing activities funded by the $249 M Other NIH Institutes received in the CARES Act Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 27, 2020 7:39 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l>;Auch incloss, Hugh (NIH/NIAID) [E] (b)(6); NIAID 0CGR l eg ; McGowan, John J. (NIH/NIAID) [E] (b)( >; Harper , Jill (NIH/NIAID) [E] (b)(6)>; ------~~ ---:---~====::::!.:.--~~ Crum, Wayne (NIH/NIAID) [E] CbH6l>;Erbelding, Emily (NIH/NIAID) [El (b)(6); Lane, Cliff (NIH/NIAID) [E] (b)( >; Rotrosen, Daniel ":"' (N -:'l"."".' H/-:-N"."'."' IA "."".' l':"" D:--: ) [~E]:-====-_;__...;. (b "'"')~(6l> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (N IH/NIAID) [E] (b)(6)· Conrad, Patricia (NIH/N IAID) [E] CbH6l>;Marston, --------- Hilary (NIH/NIAID) [E] (b)(6)>; Lerner, Andrea (NIH/NIAID) [EJ Doepel, Laurie (NIH/NIAID) [E] (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6); Routh, Jennifer {NIH/NIAID) [E] CbH6J> ; Stover, Kathy (NIH/NIAID) [El (b)( >; Law, Kim (NIH/NIAID) [El CbH6J> ; Lee, Kun-Lin {NIH/NIAID) [E] CbH6J>;Bushar, Nicho las (NIH/NIAID) [El (b)(6J; Schneider, Johanna (NIH/NIA ID) [E) CbH ,> Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending- Weekly Report Ending 3/26/20 (b)(6) 1 ; --------Tony, YTD spending is $2 1.6M, a weekly increa se of $4.0M for clinica l trial site set-up for therapeutics, further vaccine development, small animal development, and therapeutic development (mAhs) and basic research. Most of the $50M -$60M we listed last week we expect to be awarded before March 31 . In many cases contractors have begun work without the award so as to not stall work. Early next week I' 11prov ide a summary spending plan for the addi tional $706M that NIAID rece ived in the suppl ementa l appropriation signed by the President today. Martin From: Johnson, Mart in S. (NIH/NIAID) [El Date: Friday, March 20, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J>;Auchincloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper, Jill (NIH/NIAID) [E] (b)(6J>;Crum, Wayne (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6)>; Lane, Cliff(NIH/NIAID) [El (b)( > Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El (b)(6J; Conrad, Patricia (NIH/NIAID) [El (b)(6J>; Marston, Hilary (NIH/NIAID) [El (b)( >; Lerner, And rea (NIH/N IAID) (El (b)(6); Doepel, Laurie (NIH/NIAID) [El (b)(6) ; Gilles, Sharon (NIH/NIAID) [El (b)(6J>;Routh, Jennifer (NIH/NIAID) [El CbH >; Stover , Kathy (NIH/NIAID) [El (b)(6)>; Law, Kim (NIH/NIAID) [El (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6)>; Bushar, Nicholas (NIH/NIAID) [E] (b)(6) Schneider, Johanna (NIH/NIAID) [E) CbH6J> Subject: RE: FY2020 - COVID-19 -Ac tual and Forecasted Spending - Weekly Report Ending 3/19/20 -----~~ ":"---:-----:-~=====!.-:.--~= --------- ---:-----===:!.:.,_ _ ____:~~ Tony , YTD spending is $ l 7.6M, a weekly increase of $3.SM for clinica l trial site set-up, therapeutic development (mAbs ) and basic research. (b)(5) We greatly appreciate all your hard work. Martin From: Johnson, Martin S. (NIH/NIAID) [E] Date: Friday, March 13, 2020 6:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auchincloss, Hugh (NIH/NIAID) [E] ---:---~-==== (b =)=(6) ~>....:. ;_N_IA _I_D_O~C~GR Leg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIAID) [El (b)(6); ""."":""::-'."."'"-:-=":--:-:"::.======-..;-~~ Crum, Wayne (NIH/N IAID) [El (b)(6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>;Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (bH6l>; Lerner, Andrea (NIH/NIAID) [E) ~~~~~== (b =)=(6) ::::=, > ..:, ;_o_o_e;_ pe_l,:.:L.,.., a=urie (NIH/NIAID) [El (b)(6)>; Gilles, Sharon (NIH/NIAID) [El (b)( >; Routh, Jennifer (NIH/NIAID) [E) (b)(6)> ; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Law, Kim (NIH/NIAID) [E] (b)(6)>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6); Bushar, Nicholas (NIH/NIAID) [E] (b)(6)>; Schneider, Johanna (NIH/NIAID) [E) (b)( > Subject: RE: FY2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/12/20 --------Tony, Since we our last report we have increased spending on the COV ID-19 response by $1.SM for a total YID spending of $14.lM. The $ I .SM increase is for the following: $ 1.0M awarded to set-up clinical sites at Emory and U. Washington Seattle for adaptable RCT of rerndesivir. $0.4M supported data analysis of rhesus animal model and grant to gain understanding of the host pathways that regu late viral gene expression and viral subversion of the host immune system. $0. lM funded vaccine development at VRC and DIR (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, March 6, 2020 5:31 PM ------~~ ---:----:-~====:!...:.--~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Auch incloss, Hugh (NIH/NIAID) [El (b)(6)>; NIAID OCGRl eg ; McGowan, John J. (NIH/NIAID) [E] (b)(6)>; Harper , Jill (NIH/NIAID) [El (b)( >; Crum, Wayne (NIH/NIAID) [El (b)(6) Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6J>; Conrad, Patricia (NIH/N IAID) [E] CbH ; Marston, Hilary (NIH/NIAID) [E] CbH6l>; Lerner, Andrea (NIH/NIAID) [El CbH6J; Doepel, Laurie (NIH/NIAID) [E] (b)(6) Gilles, Sharon -:-: (N -:-: l:-:H/";".' N"."'." IA -:-:1-:D:-: ) [:':". E]:-===::;.___;,~ (b ,....,. )-:-= (6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El CbH6J;Law, Kim (NIH/NIAID) [El CbH6J>; Lee, Kun-Lin (NIH/NIAID) [El (b)(6) Subject: RE: FY 2020 - COVID-19 -Actual and Forecasted Spending - Weekly Report Ending 3/5/20 Tony, Since we our last report we have increased spending on the COVID-19 response by $0.2M for a total YTD spending of $ 12.6M. The $0.2M increase is for vaccine candidate development at NIA ID Intramural Labs including RML. Costs are mostly for staffing and overhead and include a preclinical immunogen icity study designed to test the mRNA-1273 nCoV vaccine two -dose schedule in mice. The study will measure the immune response to this vaccine in an animal model in anticipat ion of clinical test in humans. (b)(5) Martin From: Johnson, Martin S. (NIH/NIAID) [El Date: Friday, February 28, 2020 11:57 AM To: Fauci, Anthony (NIH/NIAID) [E] CbH6>>; Auch incloss, Hugh (NIH/NIAID) [E] (b)(6)>; NIAID OCGRLeg ; M cGowan, John J. (NIH/NIAID) [El (b)(6)>; Harper , Jill (NIH/NIAID) [E] (b)(6); Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)( >; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6)1 >; Routh, Jennifer (NIH/NIAID) [El CbH6>>; Stover, Kathy (NIH/NIAID) [El CbH6>>; Law, Kim (NIH/NIAID) [El CbH6>>; Lee, Kun-Lin (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending - Weekly Report Ending 2/27 /20 ------~~ ----------:---~---::====::!......:.--~~ Tony, Since we our last report we have increased spending on the COVID- 19 response by $2 .3M for a total YTD spending of $ 12.4M. A recap of the $2.3 million spent in the last week is as follows : • $ 1.9M to set-up a Phase I trial (45 subjects) of the VRC/Modema mRNA platform candidate at Kaiser Pennanente Washington Heal th Research Institute (One of the VTEUs ) • $0.3M that supported University of Hong Kong research ers in the developme nt of a RTPCR test to detect SARSCo V2 from human samp les. The group has now shared the tests and relevant reage nts with over 30 labs globally to enab le diagn osis of COVID- 19. • $0.lM vaccine candida te development at NIAID Intramura l Labs (b)(5) Mart in From: Johnson, Ma rtin S. (NIH/NIAID) [El Date: Friday, February 14, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b.~= .,.. c6)>;Auch incloss, Hugh (NIH/NIAID) [El NIAID OCGRl eg ; McGowan, John J. -----.~~===~..:__--~ (NIH/NIAID) [El Harper , Jill (NIH/NIAID) [E] (b)(6)> ; (b)(6)>; (b)(6)>; Crum, Wayne (NIH/NIAID) [El (b)(6)> Cc: Eisinger, Robert (NIH/NIAID) [El (b)(6)>; Folkers, Greg (N IH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/N IAID) [E] (b)(6)> ; Marston, Hilary (NIH/NIAID) (E] (b)(6)> ; Lerner, Andrea {NIH/NIAID) (E) (b)(6)>; Gilles, Sharon (NIH/NIAID) [E] (b)(6) Subject: FY2020 - COVID-19 - Actual and Forecasted Spending as of 2/13/20 -------Dr. Fauci, Attached is a narrative we are updating weekly for NIAID's COV ID-19 response. The accomp anying spreadsheet summar izes the figures and includes a summa ry of our supplemental request. We' II provide an update by Thursday of next week. Martin Resource Planning and Mission Integration Branch (RPMIB) - NIAID NIH Bldg . 3 1 Room 7A47 Tel: (b)(6) From: Fauci, Anthony (NIH/N IA ID) [El Sat, 2 May 2020 18:22 :37 +0000 Fauci, Anthony (NIH/N IAID) [El Date: To: (b)(6) Cc: Subject: RE:RE: Zeke: Thanks for your note. CbH6)and I would love to get together with you all for dinner. Let us try to do so within a reasonab ly soon time frame. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E] (NIH/NIAID) [E] Date: Saturd ay, May 2, 2020 7:24 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: RE: ---------- ------~= -------- Email from Zeke Emanue l. Robert W. Eisinger, Ph.D. Special Assistant for Scie ntific Projects Immediate Office of the Director Nat iona l Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( (b)(6)> (b)( > On Behalf Of Fauci, Anthony ------------- From: Emanuel, Ezekiel J Date: Friday, May 1, 2020 8:04 PM (b)( > ~= To: Fauci, Anthony (NIH/NIAID) [E] Cc: Subject: Re: RE: ------------------- Tony You are national--internationa l --treasure . And we are depending upon your sanity and smarts. We can have you and CbH6)overfor dinner on the porch and order in from something. Anytime you are ready. Eze kiel .J. Emanu el, M.D., Ph.D. Vice Provo st of Global Initi atives Chair, Departmen t of Medical Ethics and Hea lth Policy -------- Levy University Professor Co-Director , Heal thcare Transformation Institute Perelman School of Medicine and The Wharton School University of Pennsylvania Phone: Cb> (6) (b)( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J Cc: Subject: RE: RE: (b)(6) ------------------- Zeke: (b)(6) (b)(6) Cb)(6) or (b)(6) Thanks for the note. Indeed, we do agree. I look forweard tochatting with you some time soon. Best, Tony > -------Date: Thursday, April 30, 2020 6:37 PM -==, Fauci, Anthony (NIH/NIAID) [E] ------------Subject: Re: RE: From: Emanuel, Ezekiel J (bH To: (b)(6)> Sorry for misreading what you said--1 think maybe I overin tepreted- -lots of f inance people called and seemed like I was a downer compared to you. But I think we agree. Are you and --- (b)(6) doing okay? Ezekie l J. Emanuel, M.D., Ph .D. Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy -------- Levy University Professor Co-Director , Heal thcare Transform ation Institute Perelman School of Medicine and The Wharton School University of Penn sylvania Phone: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] ______ Date: Thursday, April 30, 2020 5:33 PM To: Emanuel, EzekielJ (b)~ > Subject: RE: _)_C6) (b _> (b)(6) Zeke: I did not "strongly " endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and better drugs. I said that it was important because it proved in a well-powered, randomized , placebo-contro lled clinical tria l tha t one can suppress t he virus enough t o see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat with you about it. Best, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Emanuel, Ezekiel J (b)(6)> -------To: Fauci,Anthony (NIH/NIAID) [E]--------=-=~ ______ _> Cb _<_ > Date: Thursday, Apr il 30, 2020 2:12 PM Subject: Tony , I hope you and (b)(6) are doing well. You are doing an amazing job under difficult circumstances . And just know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir . Was it just a bit forced? My reading was the data were weak and in normal times for norma l disease it is not enough to to approve. And very unlikely to really impact COVID-19 disease pattern --regardless of supply issues. Stay safe Ezek iel J. Emanuel , M .D., Ph.D . Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Health Policy Levy Unive rsity Profe ssor Co-Director, Healthcare Transformat ion Institute Perelman School of Medicine and The Wharton Schoo l University of Penns ylvania Phone : (b)(6) -------- Cb)< ) From: Date: To: Subje ct: Fauci, Anthony (NIH/N IA ID) [E) Sat, 2 May 2020 18:00 :31 +0000 Hurst , Natalie R. EOP/OVP RE: Update - Whi te House Coronavir us Task Force Meet ing Thanks, Nata lie ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (bX5)-PCE From: Date: To: Cc: Subject: Faud,Anthony (NIH/N IAID) [E) Sat, 2 May 2020 17:57 :11 +0000 Conrad, Patricia (NIH/NIAID) [E) B~rasch, Kir,1bt?rly(NIH/NIAID) [C] FW: Greetings from India Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. (b)(6)> From: Prof. Chirantan Chatterjee Date: Saturday, May 2, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ----====!---~~= Cc: Deepak Bhatt Manager - Communicat ions Subject: Greetings from India -------::-::-:-= _________ ... (b)(6) Dear Dr Fauci, My greetings from India. I am a health econom ist and management professor at the Indian Institute of Management, Ahmedabad, India's premier management schoo l. Also, i am a avid fan of your work even fr om pre-covid19 days. I write to you requesting some time if possible to do a podcast of 45 minutes with you over zoom. The science and policy ecosystem in India i think would immensely benefit if you can offer your thoughts on what should be India's 12-month strategy going forward for COVID-19. We have done some recent podcasts relate dly and they are listed her (https://m .soundcloud.com/healthcastbycmhs/l. If you agree, and we are flexible all of May, my communication head Mr. Deepak marked in the email will arrange the zoom logistics and make it as seamless as possible for you. We w ill also go per your t ime zone conveniences and do this ov er webex/hangout/skype or phone call if t hat helps. It would be a del ight Dr. Fauci if you can j oin us in th e conversation, loo king forward to hearing from you. Our respectful namaste from India for all th e brave work you are doing. g My best, Chirant an ChIran tan Chatterjee (PhD, Carnegie Mellon ) 11Associate Professor (Economics & Business Polley) & ICICI Bank Chai r In Strategic Managemen t 11 Chairperson, Center fo r Managemen t of Health Services at IIM A 112019 -2020 Visiting Fellow, 20 18-2019 Campbell & Edward Teller Nati onal Fellow, Hoover Inst itu tion , Stanford University 11Office Address Wing lS F, Indian Institu te of Management 11Ahmedabad, 380 015 Gujarat, India ! I Skvpe: --- ~"-"'~ 11Email:____ _. =--= ____ _,_!?}-® I I Hoover Inst it ution Website I IIMA Official Website What is laid down, ordered,factual is never enough to erobrocethe whole truth: life alwaysspills over the rim of everycup. - Boris Pasterna k in Bridges to Infi nity: Th e Human Side of Mathematics (1983) by Michael Guillen From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 2 May 2020 12:08 :00 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIA ID) [E);Haskins, Melinda (NIH/NIA ID) [E]; Barasch, Kimberly (NIH/NIAID) [CJ Subject: FW : Congresswoman Sheila Jackson Lee invites your participation in a Virt ual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT Attachments : Dr. Anthony Fauci - Town Hall lnvite.pdf Please take a look at this . We obviously will have to get clearance through HHS and White House Leg. This is for Th ursd.iy .ind so we would need to submit soon. From: Coney, Lillie Date: Friday, May 1, 2020 11:23 PM ------------ (b)(6)> --------------~= .,;,__;_ _ __;,,..;;_:-======,;:~;-:-----:-::-::---.:======---=-=- To: Fauci, Anthony (NIH/NIAID) [E] (b)( Cc: Rushing, Glenn (b)( ; Coney, Lillie (b)(6) Subject: Congresswoman Sheila Jackson Lee invites your participation in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT ----------- ---------- May 1, 2020 Dr. Anthony Fauci, M.D. Director of the National Institute of Allergy and Infectious Diseases Department of Health and Human Services 5601 Fishers Lane Bethesda, MD 20892-9806 Dear Dr. Fauci: Thank you for your tremendous steadfast leadership during this pandemic and health crisis. Our nation has not faced a crisis of this magnitude since the 1918 Spanish Flu, but we will travel this journey together and defeat this virus . In the end, the nation will become stronger and more prepared. Your participation is requested in a Virtual Town Hall meeting hosted by ABC affiliate Channel 13 in Houston, Texas on Thursday, May 7, 2020 at 7:00 PM CDT. This town hall meeting will focus on testing and guidelines for re-opening our nation. It is scheduled to last an hour with 2 or 3 guests including yourself. Houston is the fourth largest city in the country and your knowledge and expert ise would be most helpful in our fight to keep our infection and fatality rates low for this entire region and the State of Texas . My offic e has been pushing testing and setting up testing sites since the first notification of the coronavirus . We currently have seven active testing sites and expanding each week to get to the mass testing necessary to flatten the infection rate . Thank you for your consideration of this request and I look forward to participating with you in the Virtual Town Hall meeting. Again, thank you for your leadership. Please RSVP or if you have questions regarding this request with Glenn Rushing, my Chief of Staff at .___ ____, CbH6)and Lillie Coney , my Chief Policy Advisor a Cb H6) Very truly yours , J Sheila Jackson Lee Member of Congres s Regar ds, Lillie Con ey Policy Director Congre sswoman Sheila J ackson Lee (TX-18) 2079 Rayburn HOB Washingto n , DC 205 15 (b)(6) From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Sat, 2 May 2020 12:01 :04 +0000 (b)(6) Subject: FW: RE: Let us try to do this next weekend. ~90n Behalf Of Fauci, Anthony From: Eisinger, Robert (NIH/NIAID) [E]..._________ (NIH/NIAID) [E] Sen t: Saturday, May 2, 2020 7:24 AM To: Fauci, Anthony {NIH/NIAID) [E]-----Subject: FW : RE: --=(b=)(=6) Email from Zeke Emanuel. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone : (b)(6) Email: (b)( From: Emanuel, Ezekiel J Sen t : Friday, May 1, 2020 8:04 PM To: Fauci, Anthony {NIH/NIAID) [E] -------- (b)( > ------~= Cc: Subject: Re: RE: ------------------- (b)(6)> (b)(6)> Tony You are national--internationa l --treasure. And we are depending upon your sanity and sma rts. We can have you and CbH6)overfor dinner on the porch and order in from someth ing. Anytime you are ready . Ezekiel J. Emanuel , M.D., Ph.D . (b)(6) or Vice Provost of Global Initiatives Chair, Departm ent of Medical Ethics and Hea lth Policy ______ Cb _>'_ <6j) Levy University Pro fessor Co-Dir ector , Hea lthcar e Transform ation Institut e Perelman School of Medicine and The Wharton School Univer sity of Penn sylvania Phone: (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 6:55 PM To: Emanuel , Ezekiel J _______ ,.... (b) (6lv > (b)(6)> ------------------ Cc: (b) ( > Subject: RE: RE: Zeke: Thanks for the note . Indeed, we do agree . I look forweard tochatting with you some time soon. Best, Tony From: Emanuel, Ezekiel J Date: Thursday, April 30, 2020 6:37 PM -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: RE: (b)( ------~~ (b)(6) > (b)(6)> Sorry for misreading what you said--1 think maybe I overin t epreted-- lots of finance people called and seemed like I was a downer compared to you. But I think we agree. Are you and ---- CbH6Jdoing okay? Ezekiel J. Emanuel, M.D., Ph.D. Vice Provost of Global Initiatives Chair, Depa1tment of Medical Ethics and H ealth Policy ______ Cb _>_ <) L evy University Professor Co-Director , Healthcar e Transform ation Institut e Pe relman Schoo l of Medicine and The Wharto n Schoo l Univer sity of Pennsylvania Phon e: ----------- (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 5:33 PM To: Emanuel , Ezekiel J Subject: RE: (b)( (b) ( > > Zeke: I did not "strongly" endorse it. I specifically said tha t it was not a knockout drug and was only a baby step in the direction of develop ing more and bette r drugs. I said that it was important because it proved in a well-powered, randomized , placebo-controlled clinical tria l tha t one can suppress t he virus enough to see a clinical effect, as modest as the effect was. I do not think I forced anything. Happy to chat w ith you about it. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Emanuel, Ezekiel J (b)(6) Date: Thursday, April 30, --------2020 2:12 PM Fauci, Anthony (NIH/NIA ID) [E]--------------- == Subject: To: (b)( 6) Tony, ---- I hope you and (b)(6) are doing we ll. You are doing an amazi ng job unde r difficult circumstances. And ju st know we prefer the "real" Tony to the Brad Pitt version!!! I am a bit perplexed by your seeming strong endorsement of remdesivir. Was it just a bit forced? My reading was the dat a were weak and in normal times for normal disease it is not enoug h to t o approve. And very unlikely to really impact COVID-19 disease pattern--rega rdless of supply issues. Stay safe Eze kiel J. Emanu el, M.D ., Ph.D. Vice Provost of Global Initiatives Chair , Departm ent of Medical Ethic s and Health Policy -------- Levy University Professor Co-Director, Healthcare Transformation Institute Perelman School of Medicine and The Wharton School University of Penn sylv ania Cb)< ) ----------....1 Phone: Cb> (6) From: Fauci, Anthony (NIH/NIAID) [El Date: Sat, 2 May 2020 02:04:00 +0000 To: Selgrade, Sara (NIH/NIAID) [El Cc: NIAID OCGRLeg;Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELP Hearing Attachments : 2020 .05.12 NIAID Senate HELPtestimony COVID 19 - with Fauci tracked changes.docx I am attac hing the document with minor tracked edits. Nice jo b! Thanks. From: Selgrade, Sara (NIH/NIA ID) [E) (b)(6)> Date: Thu rsday, April 30, 2020 5:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: NIAID OCGR Leg ; Billet, Courtney (NIH/NIAID) [El CbH6J>;Folkers, Greg (NIH/ NIAID) [E (b)( >; Conrad, Patricia (NIH/ NIAID) [E] (b)(6) Subject: Requesting your assistance : Draft NIAID Statement for May 12 Senate HELPHearing Dr. Fauci: In preparat ion for the upcoming May l ih COVID-19 hearing of the Senate Health, Educa tion , Labor, and P ens ions Committee (Chair : Sen. Lamar Alexander, R-TN), we have drafted the attached NIAID testimon y, bu ilding on your prior testimony on COVID-19. Dr s. Giroi r, Hahn, and Redfield also have been invited to the hea ring. We expect that your testimon y will be included as an insert to an HHS-wide testimony. At the request of NCH OD, we ha ve incorporated into the draft COVID19 activ ities across N IH . The testimon y ha s been reviewed by the Divi sions and Dr s. Lane , Harpe r, Marston, and Lerner , as well as Courtney Billet , Greg Folkers, Martin Johnson , and Lauri e Doepel. NIH OLPA has aske d to receive your testimony for clearance by tomorrow, if possi ble . Thank you for your help. Sara Sara Selgrade, Ph .D . Sect ion Chief for Legislative Activities Legislative Affairs and Con-espondenceManagementBranch Office of Communicationsand GovernmentRelations NIAJD/NIH/DHHS Bldg. 31,Room 7Al7, MSC 2520 Bethesda, MD 20892-2520 Phone: (b) (6) (b)(6) Disclaimer: The i11for111atio11in this e -111ail and a.11yof its altac/1111c11ts is co ,!fide:ntial and ,nay c:ontai n sensitive i11fon11,1tio11.it ,-,·l,ou/d not b e used by anyone who is not the original intended recipienl. lf you have rr?ceivedthis e-mail i11error please inform the sender and delete it from y our mailbox or any other storaw; devices. National Institute ofA!lerf!)' and Infectious Dise,ases shall not accept liabili(v,(orany slatements made !hat are sender's own and not e,xpresslymade 011behalf of ,he NJAID by one o/ils representatives , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Fri, 1 May 2020 15:28:23 +0000 Routh, Jennifer (NIH/NIAID) [El RE:cl ips Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/ NIAID) [E] (b)( > Se nt : Friday, May 1, 2020 8:56 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Billet, Courtn ey (NIH/NIA ID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( > Subject: RE:clips --------, .....,....,= --------Dr. Fauci- I have requested the full clips from our clipping service . I found t he following on line in the meantime: Today Show: https://www .today .com/video/ d r-a ntho ny-fa uci-rem d esivir-is-a-very -i m port ant -fi rst-step-in-fighti ngcoronavirus-82800 197863 CNN Town Hall (clip discussing federal "reopening" guidel ines): https://twitter .com/CNN/status/1256023483638669313 CNN Town Hall (clip discussing vaccines) : htt ps:// twitter .com / CNN/ status / 1256044817093558272 Thanks, Jen Jennifer Routh [E] News and Science Writing Branc h Office of Commu nications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sensit ive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statementsmade that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Friday, May 1, 2020 7:44 AM To: Routh, Jennifer (NIH/NIAID) [E] Subject: clips --------- (b)(6) ---------=--:-= > --------- (b)( Jen: Can we please make sure that I get the lip s from yesterday from NBC Today Show and CNN Town Hall with Sanjay and Anderson. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information_ It should not be used by anyone who is not the orig inal intended recipient_ If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices _ The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives_ From: Date: To: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Fri, 1 May 2020 12:26:55 +0000 Fauci, Anthony (NIH/NIAID) [E) Subject: FW: [El (b)( 4) Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email : (b)( From: Kalil, Andre C (b)(6)> Date: Thursday, April 30, 2020 8:12 PM To: Beigel, John (NIH) [El--:-:-::-:--:.=======.:.'"""'""-:-= (b)( ; Davey, Richard (NIH/NIAID) [El (b)( ; Lane, Cliff (NIH/NIAID) [El (b)(6)>; Proschan, Michael (NIH/NIAID) [E] (b)(6l>; Marston, Hilary (NIH/NIAID) [E] (b)( ·>; Fauci, Anthony (NIH/N IAID) [El (bH > Subject: RE: (b) (4) (b) (4) Thanks, Andre Andre Kalil , MD, MPH, FACP, FIDSA , FCCM Professor Department of Internal Medicine Division of Infectious Diseases Director, Transp lant ID Program Associate Editor. CMI. Official Journa l of ESCMID Editoria l Board. CCM. Official Journal of SCCM l' UNMC. -,- t(JltUt.• Univers ity of Neb raska Medical Center 985400 Nebraska Medical Center. Omaha. NE 68198-5400 (b)(6) I fax 402.559-5581 (b)(6) UNMC I Facebook I Twitter I You Tube I~ "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probabilities ..." Robert Ludlum - The Amb ler Warning From: Beige!, John (NIH) (E] -------- Date: Thursday, April 30, 2020 5:25 AM ------ (b)( > --,;-,,= To: Dodd, Lori {NIH/NIAID) [E] (b)(6)>; Kalil, Andre C (b)(6)>; Davey, Richard (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/NIAID) [E] (b)( >; Proschan, Michael (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6); Fauci, Anthony (NIH/NIA ID) [E] (b)( > (b)( 4 Subje ct: Re: ~====~~ ------------- Non-UNMC email (b) (4) John B eige), M.D. Associate Direc tor for Clinical Research Division o f Microbiology and Infectious Disea~es National Institute of Allergyand Infectious Diseases(NIAID) From: Lori Dodd CbH6)> Date: Thursday , Apr il 30, 2020 at 6:05 AM To: John Seigel (b)(6)>, (b)( >, =========~~ Andre Kalil Cliff Lane (b)(6)>, (b)(6), Hilary Mars ton (NIH/ N IAID) ,;..IE-=-]'..:: ' ====== Subject: RE: (b)(6)>, Richard Davey Michael Proschan ---------- (b)(6)> , "Fauci, Anthony (b)=C6) ::_--=-:-.,.,,,, (b)(4) -------------- Andrei like what you wrote, and partic ularly like the first two sentences. From: Beigel, Jo hn (NIH) (E] (b)( > Date: Thursday, April 30, 2020 5:53 AM To: Kalil, Andre C (b)(6)> ; Davey, Richard {NIH/NIAID) [E] (b)(6)>; Lane, Cliff {NIH/NIAID) [El (b)( >; Dodd, Lori (NIH/NIAID) [El (b)(6)> ; Proschan, Michael (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)>; Fauci, Anthony (NIH/NIA ID) [El (b)( > Subject: Re: (b) (4 Andr e, (b) (4) We too are open for further edits John John Beige), M.D. AssociateDirector for Clinical Research Div ision of Microbiology and Infectious Diseases NationalInstitute of Allergy and Infectious Diseases (NIAID) Phone: email::=.=====:: ~= From: Andre Kalil (b)(6)> Date: Thu rsday, April 30, 2020 at 3:19 AM CbH6J>, Richard Davey CbH >, Cliff Lane (b)(6), Lori Dodd CbH6)>,Michael Proschan ~=======~~ (b)( >, Hilary Marston (b)(6)>, "Fauci, Anthony "':'---:--:-:--:--:-::.====:::;_;,--..;...,; = (NIH/NIA ID) [E)" CbH6)> To: John Seigel Subject: -------------- (b) (4) Please let me know your t hough t s and suggestions. Andre Andre Kalil, MD, MPH, FACP, FIDSA , FCCM Professor Department of Interna l Medicine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journal of ESCMID Editorial Board , CCM , Official Journal of SCCM ~ UNMc· ~ f<)\U:,_. University of Neb raska Medical Center 985400 Nebraska Medical Center , Omaha , NE 68198-5400 ___ (b)_ (_, 6) I fax 402.559-5581 (b) (4) (b)(6) UNMC I Facebook[facebook.com) I Twitter (twitter.com) I YouTube [youtube.com)I Flickr [flickr.coml "Lucky? Obviously you haven't heard anything I've said . It was a matter of applying Bayes' Theorem to estimate the conditiona l probabilit ies. Giving due weight to the prior probabil ities ..." Robert Ludlum - The Amb ler Warning The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this information is prohibited. If you have received this e-mail by mistake, please delete it and immediately contact the se nder . The information in this e-mail may be privileged and confidential, intended only for the use of the addressee(s) above. Any unauthorized use or disclosu re of this informat io n is prohibit ed. If you have received this e-mail by m istake, please delete it and immediately contact the sender. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:25:50 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( ----------------=-:-:= From: Dani Bolognesi, Ph.D. Se nt : Thursday, April 30, 2020 8:13 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct : RE: -------- (b)(6) (b)(6)> TX Tony. Nice touch reminding fo lks of how AZT propelled the pharmas and great to see things moving with this beast! Sei un campione ! Dani From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, April 30, 2020 7:58 PM ------~~ To: Cassetti, Cristina (NIH/NIAID) [E:,.!: ] ======= Cc: Erbelding, Emily (NIH/NIAID) [E).__ _______ Subject: FW: (b) ( > (b =)~(6);',.>= Cb _H_6J Cristina: Please take a good look at th is. It is from Dani Bo lognesi, one of our top HIV/ A IDS invest igators from a few years back . He is a ser ious scientist. Let me know what you th ink. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) [E) (NIH/NIAID) [E] Date: Monday, April 27, 2020 6:57 PM ----------- (b) (6J> On Behalf Of Fauci, Anthony To: Fauci, Anthony (NIH/NIAID) [E].__ _____ Subject: FW: (b_H""""'"'" v> Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office o f the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Dani Bolognesi, Ph.D. Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= ----------------(b)(6) (b)(6)> (b)(6)>; Barasch, Kimberly (NIH/NIAID) [C] Subjec t : FW: Kimberly: Please see that t his reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getti ng together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) (b) (4). (b) (5) We are prepared to discuss this with you and your team at any time that is convenien t for you . As you may know, we are locked down here in the Research Triangle unt il May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opport unity to share th is with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M.D." Subject: Please review th is draft email to Tony -- TX (b)(6 )> ------------=-:-=, ------------(b)(6) Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . Allthe best, Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensiti •,e, protec ted information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immed iate ly by return electronic mail, and to delete it without further reading or retent ion . The informat ion is not to be forwarded to or shared unless in compliance with Duke Healt h policies on confidentiality and/o r wit h the approva l of the sender . Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Fri, 1 May 2020 12:10:09 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: ACTT pub lication High From: Date: To: Subject: Importance: Another email from Andre Kalil. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email (b)( From: Kalil, Andre C (b)(6)> Date: Friday, May 1, 2020 2:59 AM To: Seigel, John (NIH) [El ------~~ > ; Davey, Richard (NIH/NIAID) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6l; Dodd, Lori (NIH/NIAID) [E] (b)(6)>; Proschan, Mic hael {NIH/NIAID) [E) (b)(6) Marston , Hilary (NIH/NIAID) [E] (b)( ; Fauci, Anthony (NIH/N IAID) [El (b)(6) Subject: FW: ACTT publication Impo rt ance: High (b)( ======~~ Not my first choice, but I want to share the invitation email below with you. Andre Andre Kalil , MD, MPH , FACP , FIDSA , FCCM Professor Department of Interna l Medi cine Division of Infectious Diseases Director, Transp lant ID Prog ram Associate Edito r, CMI , Official Journa l of ESCMID Editoria l Board , CCM , Official Journal of SCCM If UNMC-.ut1BIUGHl !'MIA.· Uni vers ity of Nebr aska Medi ca l Cen ter 985400 Nebraska Medical Center , Omaha , NE 68198-5400 (b)(6) I fax402.559-5581 ===~ (b):..:c (= 6) UNMC I Facebook I Twitter I YouTube I Flickr "Lucky? Obviously you haven't heard anything I've said . It was a matter of app lying Bayes' Theorem to estimate the conditional probabilit ies . Giving due weight to the prior probab ilities ..." Robert Ludlum - The Amb ler Warning ------------------ From: (b) (4) Date: Thursday, April 30, 2020 1:03 PM To: Kalil, Andre C (b)(6) Subje ct: ACTTpublication Importance: High Non-UNMC email Dear Dr. Kalil, (b) (4) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: int erview request by Greek newspaper Ethnos FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX:(301)4 96~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: ru.:.,pyo<;ha¢u5ac; Date: Friday, May 1, 2020 6:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: inte rview request by Greek newspaper Ethnos ------ --=~ Dear Dr. Fauci, my name is George Skafidas and I'm a journal ist working for the Greek nationa l weekly ETHNOS (www.ethnos.g r). We would be very much interested in doing an interv iew with you, to be published in the Sunday edition of the paper, regarding the developments surrounding t he COVID-19 pandemic. Best regards EG>NOE George Skafidas Senioreditor, World Affairs tel: +30 210 6510550 mob: o, n>-ripocpopiE<;nou (b)(6) nEp1txovT01 aE OUTOTO µ~vuµo 11>-E>TO OUVKEKplµEVO nopoArimr, (-E<;). o, nAr,pocpopiE<;OUTE<; µnopEi VO KOAUnTOVTOI on6 EnlXEIPrJOIOKO ri 6>>.oon6pprJTOri oAAouc;v6µouc; KOiOEVEnlTpEOETOI VO OVOKOIVW9ouv -r'lnTfJ, anoyopt:U€TOI VO TO OVOKOIVWO"E:Tt, OVTIYPOljJE:"TE:, o,ovciµE:"TE: ri OIOTrJPriOE:TE: E:V6Awv ri EV UEPEI. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Fri, 1 May 2020 11:38:08 +0000 To: Subject: (b)(6) RE:Coronavir us: Covid 19 Ato: Thank you for you note . We will know soon whether hydroxychloroquine has any beneficial effec ts as the results of randomized, controlled trials become available. The pathogenesis of COVID-19 is sti ll an open question . You are correct in that ther e is a mor e recent tendency to use ventilators only as a very last resort since oxygenation rathe r than ventilation appears to be key to recovery. Best regards , Tony Anthony S. Fauci, MD Direc tor National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Inst itutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: gabriel stephens Date: Friday, May 1, 2020 4:53 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Coronavir us: Covid 19 ---------- (b)( ------~= _______(b)(6)>_. Hi Dr Fauci, Please find an audio attached of a doctor descr ibing the experience with regards to covid 19 in the hospital. She seems to suggest covid 19 is a virus tha t rather attacks the blood cell, le ading to respi ratory and other organ comp lications, hence they need to loom at tre atme nt in a differ ent light. In the UK some hospitals have moved away from using ventilators due to the high death rate of those on ventilators, and are rat her using ventilators for sleep apnea, as they are less invasive, and the resu lts are much much better compared to invasive ve ntilators There are some anecdotal observations I have also made. The infection rate in most African countries seem to be comparatively low, w hich could possibly due to the rate of testing being conducted. However t he death rates are also comparative ly very low. From in itial informat ion with regards to hydroxychloroquine and some antimalaria drugs usage, it was suggested that those who were alleged to have had some benefits had mild symptoms of covid 19. I know some clinical trials have shown hydroxychloroquine not to be effect ive in the treatment of covid 19 in very ill patients. However, my hypothesis is, are the low death rates in Africa linked to the fact that malaria is very prevelant in Africa, and lots of Africans take antimalarial drugs, making them less susceptible to covid 19, hence the low death rate. Is there a similar trend in other countries where malaria is prevalent? Is there an unintended benefit of taking antimalarial drug (or other medication) before covid infection, or at the onset, making people less susceptible to covid19 . As I said, this is based on anecdota l observations. Yours sincerely Ato Stephens From: Date: To: Fauci, Anthony (NIH/N IAID) [El Thu, 30 Apr 2020 23:58 :07 +0000 Cassetti, Cristina (NIH/NIAID) [El Erbelding, Emily (NIH/NIAID) [El Dani Bolognesi, Ph.D. Cc: Bee: Subject: FW: Attachment s: Brown et al submitted .pdf, NIH Presentation final.pptx, prepr ints202002.0147.v2 (1).pdf, Mosaheb et al 2020.pdf Cristina : Please take a good look at th is. It is from Dani Bolognesi, one of our top HIV/A IDS investigators from a few years back. He is a serious scientist. Let me know what you think. Thanks, Tony From: Eisinger, Robert (NIH/NIAID) (El (b)(6)> On Behalf Of (NIH/NIAID) [El Se nt : Monday, April 27, 2020 6:57 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Subject: FW: Fauci, Anthony (b)(6)> Email from Dani Bolognesi. Robert W . Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room ?A-03 Bethesda MD 20892 Telephone (b)(6)9 Email (b)( From: Dani Bolognesi, Ph.D.________ Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= ______ (b)(6)> Subject: FW: Cb _>_<6) _> Cb> _C6) _ >; Barasch, Kimberly (NIH/NIAID) [C] Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15 . If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportunity Allthe very best, Dani (b)(6) Best, to share th is with you ! Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." (bH6J> ------------,; ~ > Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeier, M .D." (bH Subject: Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows : (b) (4), (b) (5) We are prepare c!Tciaiscuss this wit h you and your tea at any time tnaf 1sconvenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step. All the best , Dani Best, Dani Sent from Dani Bolognesi The information in this electronic mail is sensitive, protected information intended only for the addressee(s). Any other person, including anyone who believes he/she might have received it due to an addressing error, is requested to notify the sender immediate ly by return electronic mail, and to delete it without further reading or retention. The information is not to be forwarded to or shared unless in compliance w ith Duke Health polic ies on confidentiality and/or w it h the approva l of the sender. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:35 :34 +0000 Jeremy Farrar ;Dzau, Vi ctor J.;George GAO Richard To: Cc: (b)(6);Hannon, Emma;Conrad, Patricia (NIH/NIAID ) [E];Teresa M iller de Vega; (b)( 6);Rebek a Yasmin CEPl;ben.t inker@cnn .com;Amanda.Sealy@cnn .com;Neel.Khairzada@turner.com;T ia.M iller@turner .com (b)(6)McGinnis, J. Michae l;Balatbat, Celynn e;Mun , Jenny; CbH ;Redfield , Robert R. (CDC/OD) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regard ing your Saturday April 25 part icipat ion ......."""'.""":--:'~~:--"'""":""':'".':""'."~-"'."-:".~----------===~~"'.:"""""---:"'-.-- ----- ------- Jeremy: Many thanks for the update. Please continue to keep me informed. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jere my Farrar _________ Date: Tuesday, April 28, 2020 10:39 Arvl Cb _>_<6) _ -------, --------- To: Fauci, Anthony (NIH/NIAID) [E] GAO (b)(6) > ~=; Dzau, Victor J. ; George (b)( (b)(6) Cc: Richard Hatchett (b)(6); Hannon, Emma ; Conrad, Patri cia "':'-""."'."":-'.'"-:-'.'-:-:"::.:=======:;....,. = (NIH/N IAID) [E] (b)(6); Teresa Miller de Vega ___ Cb _>_<6) _ ; Rebeka Yasmin - CEPI (b)( (b)(6) ; ben .tinker@cnn .com; ----- ~= Amanda .Sealy@cnn.com ; Neel.Khairzada@turner .com; Tia.M iller@turner. com; (b)( 6) McGinnis, J. Michael (b)(6)>; (b)( >; Mun, Jenny (b)( ; Redfie ld, Robert R. (CDC/OD) (b)( 6) Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 participation Quick update Update in confidence European network from this morning: 16 Paris, 2 Geneva, few Madrid last 10 days - nothing like this usually seen even with seasonal KD or TSS Barcelona have slightly different experience of 6 'Kawasaki' in last 2 weeks - couple now who have large coronary aneu rysms, as have one child South London and one in Bristol. Most UK PICU have 1-2 of these type of cases Phenotype seems Diarrhoea and abdominal pain, refractory shock then various degrees of heart invo lvement and inflammation ++ - several have had their normal appendix whipped out Most negative respiratory and stool PCRfor anything, some positive resp PCRCOVID - GOSH early case has seroconverted, but had immunog lobu lin We are establishing database UK and Europe and trying to define what the clinician features are and agree investigat ions. Notably , none in US reported (just 0/W Boston childrens who have been running shared international COVID experience web calls) and none in Rome, unsure about rest of Italy yet Does seem BAME preponderance-?? immune related or social phenomenon, in terms of deprivation prevalence and ability to isolate From: "F auci, Anthony (NIH/NIAID) (E]" Date: Monday , 27 April 2020 at 12:36 To: Jeremy Farrar (b)(6) CbH6) , Victor Dzau , George Gao (b)(6) > Cc: Richard Hatchett Cb) (6) "Hann on, Emma " , "Conrad , CbH6), Teresa de Vega Patricia (NIH/N IAID) [E]" Cb)(6) Rebeka Yasmin - CEPI Cb)(6) , "ben. tinker @cnn.com " , "Amanda.Se aly@c nn.com " , "Neel.Kbairzada(a),turner.com " , "Tia.Miller@turner.com " , Cb)(6) "McGinnis, J.Mic hael" , CbH6) >, ''Mun , Jenny" , CbH6l, "Redfield , Robert R. (CDC/OD)" ---------(b)( ---------> Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is there any more detail ed description of th e precise clinical manifestations? They describe a "mul t isystem infl ammatory state 11 • It is vasculitis or anything more specific ? Could be an infe ctiou s agent that has nothing to do with SARS-CoV-2infection even though some children are circum stanti ally inf ected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome, perhaps a Kawasaki syndrome- like disease. Please keep me inform ed if you hear any further inform ation . Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone· (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------=-=--== From: Jeremy Farrar Date: Monday, April 27, 2020 7:13 AM To: Fauci, Anthony (NIH/NIAID) [El GAO (b)(6)> (b)(6)> -------- (b)(6)>; Dzau, Victor J. ; George (b)(6) ____ ; Hannon, Emma ; Conrad, Patricia (b)(6); (b)(6) > ; Teresa Mil ler de Vega _,, (b)(6)· Rebeka Yasmin - CEPI (b)( t >; ben.ti nker@cnn.com ; Amanda.Sealy@cnn.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b) (6) McGinnis, J.Michael< M McGinnis@nas.edu>; (b)(6)>; Mun, Jenny (b)(6) Subject: Re: NAS Annual Meeting Sessionon COVID-19 -- Informat ion regarding your Saturday April 25 participation To be aware of- news over night so a huge amount of uncertainty - important for COVID19 now, and a potentia l concern for how we view immunity, prot ection, post-infectiou s immunopathology. https://www.hsj.eo.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496 .article https://t .co/Bj6YH U8zi From: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) > Date: Sunday , 26 Ap1i l 2020 at 19:52 To: Victor Dzau , George Gao CbH L---------~ Cc: Jerem y Farrar CbH , Rich ard Hatchett (b)(6) ----------- = CbH6) "Hannon, Cb)( >, Teresa de Vega CbH6) >, Rebeka Yasmin - CEP I (b)(6)"ben.tinker@cnn.com " , "Amanda.Sealy@cnn .com " , "Neel.Khairzada@turner.com " , "Tia.Miller@tumer.com " , (b)(6)"McGinnis, J.Mic hael" < MMcGinn is@nas.edu > , (b)(6)"Mun , Jenny" , (b)(6) Emma" , "Conrad , Patricia (NIH/NTAJD) [E]" Subject: RE: NAS Annual Meeti ng Sess ion on COV ID- 19 -- Information regarding your Saturda y Ap ril 25 participation It was a real pleasure to join all of you on this impor ta nt session. Many tha nks for inviting me. Anthony S. Fauci, MD Director National Institute of Alle rgy and Infectio us Diseases Build ing 31, Room 7A-03 31 Ce nter Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipie nt. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J. Date: Saturday, Apr il 25, 2020 3:59 PM Hannon , Emma ; Conrad, Patricia (NIH/NIA ID) [El (b)( ; rebeka.yasmin@cepi.net; ben.tinker@cnn.com ; Amanda.SeaIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6)>; Mun, Jenny (b)(6)>; haja.bally@cepi.net Subject: Re: NAS Annual Meeting Session on COVID-19 -- Informat ion regarding your Saturday April 25 part icipation ---------- ---------------------- Dear Jeremy, Tony, Sanjay,George, Susan and Richard, Thank yo u so much fo r your superh contri hutions. Ttwas a spectacu lar session- a trnl y inspi rin g one. I am grateful to all of you. Hope to see you soon. Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6)wrote: I am waiting for being connected and will use s lides w hich we re sent to yo ur office George '&.§ it IY:l iPhone t£ 2020~4 ~ 24 B . 0 I :49, Dzau, Victor J. '.ij'.~ : Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anyt hing you need from me. I also want to check whether you are planning to use slides. Wi ll you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor ------ PS, · (b)(6) , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Se nt : Thursday, Apr il 9, 2020 11:01 AM To: Mun, Jenny , ------~~ (b)(6) ; 'ben.tinker@cnn .com ' ; 'Amanda.Sealy@cnn .com' ; 'Neel . Khairzada@turner.com' ; (b)(6) 'Tia.Mi ller@turner.com' ; ______ .... Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regar ding your Saturday April 25 participation Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, l am sending this email in lieu of a call to prepare for the session. As you know , this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the vims, the state of diagnostic , treatment and vaccine development, and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a globa l leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic. • George Gao will discuss China's response to the pandem ic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COV ID-19 . • Sanjay Gupta will comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny Date: Wednesday, April 8, 2020 10:56 AM ben .ti nker@cnn .com'; 'Amanda.Sealy @cnn.com' ; 'Nee l.Khairzada@turner .com'; 'Tia.Miller@turner.com' Subject: NAS An nu al Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that will be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below. Please note that the session will be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NASYouTube channe l (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday, April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1 :30 pm EDT) to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting . We will list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medica l Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology, Perelman School of Med icine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk) . We can arrange for a training session this week or next week. If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any other questions, please let me know. Regards, Jenny Jenny Mun Membership Director National Academy of Sciences (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:19 :19 +0000 Alexander Patterso n RE: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Thanks, Alex! Mu ch apprecia t ed. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alexander Patterson (b)(6)> Cc: Daniel Lahart Subject: (b)( made a Video Game of Yo: "Fauci 's Revenge" Dear Dr. Fauci - My name is Alex Patte rson and I'm (b)(6) I made a v ideo game about you called Fauci 's Revenge. Link to play : https://beatthebomb .com/beatthevirus We are stream ing the Finals of a tournament live tonight at 8 PM EST o n Tw itch , FB, and YouTube. Twitch Stream Link (free to watch): https://www .tw itch.tv/beatthebomb1000 Also available on: Facebook : https://www.facebook .com/ BeatTheBomb/ YouTube: https ://www.youtube .com/channel/UCOyh7vo1knuKuaaCKUssAzA Please watch the Twitch Stream if you can! Otherw ise I will follow up tomorrow w ith a video! Media coverage of the Fauci's Revengein the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Heal th + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson~ Alex Patterson CEO BEAT TH E BOMB www.beatthebomb.com Follow us on instagram: @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work : 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:18 :45 +0000 (b)( 6) Grad made a Video Game of Vo: "Fauci's Revenge" Fauci's Revenge Game Logo.png (b)( 6) Att achment s: Yikes! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. _. _, (b)( 6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alexander Patterson Date: Thursday , April 30, 2020 11:26 Alvl To: Fauci, Anthony (NIH/NIAID) [E] Cc: Daniel Lahart Subject: (b)(6) made a Video Game of Yo: "Fauci's Revenge" Dear Dr. Fauci - My name is Alex Patterson and I'm (b)(6) I made a video game about you called Fauci's Revenge . Link to play : https:/Jbeatthebomb.com/beatthevirus We are str eaming the Finals of a tournamen t live to night at 8 PM ESTon Twit ch, FB, and YouTube . Twitch Stream Link (free to watch): httos://w w w.t w itch.t v/beatthebom b1000 Also available on: Facebook: https://www.facebook.com/BeatTheBomb/ YouTube: https:// w w w .yout ube.com/channel/UCOyh7vo1knu KuaaCKUssAzA Please watch the Tw itch Stream if you can! Otherwise I will follow up tomorrow w ith a video! Med ia coverage of the Fauci's Revenge in the News: • NBC New York Spectrum NY1 News Timeout New York News 12 New York Bushwick Daily Fox 5 Good Day New York To date we've raised over $6,150 for New York City's Public Health System (NYC Health + Hospita ls). We've created limited edition t-shirts (including a Fauci's Revenge one). We've donated 6,150 Protective Suits and 4,500 Gloves to the NYC Mayor's Office and face shields to Maimonides Medical Center. Men for others! Looking forward to be ing back in the halls soon at a Jug Night or Career Day. Enjoy the game! Best, Alex Patterson Cb)(6) Alex Patterson CEO BEAT THE BOMB www.beatthebomb.com Follow us on instag ram : @beatthebomb 247 Water Street, Suite 106, Brooklyn, 11201 work: 718-643-0200 I I cell: (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:14 :57 +0000 To: (b)( 6) Cc: Tromberg , Bruce (NIH/NIBIB ) [E];Sharpless, Norman (NIH/NCI) [E];Birx, Deborah L. EOP/NSC;Redfi eld, Robert R. (CDC/OD);Colli ns, Francis {NIH/O D) [E) ( CbH 6>11); Conrad, Patricia {NIH/NIAID ) [E] Subject: FW: Stanford National Daily Health Survey for COVID - "Open Up America Again" Attachments: 4.28.20 NDHSOverview Slides-Rusty-Fauci_ 1.ppt x Rod: Great to hear from you. Thanks very much for sending this . Very impressive! I will forward this to Bruce Tromberg and Ned Sharple ss who have been working on COVID-related apts . In addition, I have cc'd Deb Birx {Coordinator of the White House COVID-19 Task Force) as we ll as CDC Director Bob Redfield and Francis Collins. I hope that all is well with you. Stay well and safe. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Pett igrew, Roderic I Date: Thursday, Apr il 30, 2020 4:20 AM To: Anthony S. Fauci {NIH/NIAID) (b)(6) Subject: Stanford Nat ional Daily Health Survey for COVID - "Open Up America Again" ---------- ~= Hi Tony , Greetings from Houston, wher e the numb er of cases peak ed ~2 w eeks ago, dropped 35 -40% and see m ed to have plateaued since. Grea t to see you on TV and see t he na t ion (includi ng Brad Pitt©) get to know the rigorously informed, keenly rationale and consistent ly clear Tony your coll eagues have long known. (b) (4), (b) (5) Thank you , Tony . Very proud to know you. Kind regards ta ----(b)( . Rod Roderic I Pettigrew , PhD, MD CEO EnHealth I Health Science Center and College of Engineering Robert A Welch Professor and Executive Dean EnMed I Colleges of Medicine, Engineering and Houston Methodist Hospital Texas A&M University ALKEK Building ISuite 1103 2121 W Holcombe Blvd I Houston , TX 770?/J www.enmed.tamu.edu Ph:___ ...> Cb _<~ .- 1- ____ MAKING WHAT IF POS SIBLE Cb ...> _<~ ..... I whatif.tamu.edu From: Hofmann, Lawrence, M .D. Date: Tuesday, April 28, 2020 11:19 Atvl To: Pettigrew, Roderic I (b)(6) (b)(6) Cc: Pelc, Norbert J (b) (6) Subject: [EXTERNAL]NationalDaily Health Survey for COVID- "Open Up America Again" (b) (4), (b) (5) Best, R Lawrence "Rusty" Hofmann , MD Professor and Chief, lntervent ional Radiology Medical Director, Digital Health Integration Medical Director, Cardiac and lnte rventional Services @rustyhofmannMD (ml CbH6l Assistant: (b)(6) (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [El Thu, 30 Apr 2020 22:05 :19 +0000 Barillas, Carolina (N IH/NIAID) [El Auchi ncloss, Hugh (NIH/NIAID) [E] -------------------------- RE: (b) (5) Caroli na: Thanks for se ndin g thi s Best regards, ------ (b) (5) To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Baril las, Carolina (NIH/NIAID) [E] Date: Thursday , April 30, 2020 11:25 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh {NIH/ NIAID) [E] Subj ect: ------~= (b)(6) (b)(6)> ~-=======---~= (b)(6) (b) (5) Dea r Tony, (b) (5) All the best, Carolina (b)(S) (b)(5 From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 21:47 :05 +0000 To: Subject: (b)(6) FW: Autopsy data suppor t ing Remdesivir trial (b) (4) (b) (5) Take a look at t he Figures in th e manuscript. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Timothy Schacker Se nt : Thursday, April 30, 2020 1:10 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Autopsy data supporting (b)(6) -------~ ---------Remdesivir trial Tony.,__________________________________ = (b)(6l!> ~= (b) (4) Stay we ll (please) and thank you for all you are doing! Tim Timot hy Schacker , M.D. Vice Dean for Research , Medical School Director, Program in HIV Medicine Unive rsity of Minnesota Mail: MMC250 420 Delaware Street SE Minneapolis, MN 55455 FedEx/UPS: Mayo C688 420 Delaware Street SE Minneapolis, MN 55455 Phone: Cb)(6) Fax: 612-626-5599 (b)(6) email: ------- (bX5) -PCI (bXS) - PCP Fauci, Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 14:17:43 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Billet, Court ney (NIH/N IAID) [El Subject: FW: May th e Official Nobel documentary program at Swedish Television get an interv iew with you Dr Fauci about Covid-19 before May 7t h please? From: Date: Please get clearance and set it up if possible. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: .___,. ,._, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Johan Bergendorff Date: Thursday, April 30, 2020 9:56 AM ------ ::;..,..-,= To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Cc: NIAID NEWS (NIH/NIAID) ; Barasch, Kimberly (NIH/NIAID) ________ Cb _>_C6) _ >; Stover, Kathy (NIH/NIAID) [El (b)(6) ICJ Subject: May t he Officia l Nobel documentary program at Swedish Television get an int erview with you Dr Fauci about Covid-19 before May 7th please? Dear Dr . Fauci, I had the honor to interview you in april 2016 about the zika ep idem ic at your off ice for a program for national Swedish radio as their global health cor respondent. I hope I may have the ho no r again now Sir? I am now working as science corresponden t for the nat ional Swedish Te levis ion (non commercial public service, half the populat ion as daily viewe rs) in our official Nobel prize laureau t e documentary program "Vetenskapens Va rid" (the World of Science) and wonder if you have any chance to g ive us a 10 minute interview by web video before May 7th please? I would like to ask you two questions: What is most crucial now to suceed with an covid-19 pandemic exit in the US? How do you find the Swedish strategy against Covid-19 so far (Dr. Mike Ryan praised it yeasterday at the WHO press conference as a model for an exit strategy, what is your view)? In this one hour program aired on May 11th we will have other prominent scientists as well talking about exit strategies, among others Nobel prize winner prof. Paul Krugman, prof. Bengt Holmstrom MIT, prof. Angus Deaton Princeton, as well as Prof Gabriel Leung Dean University Hongkong etc. Here you can see the reports I did from my earlier interview with you about the zika epidemic in 2016 (in Swedish). News report: https://sverigesrad io.se/artikel/642089120 min docu men ta ry : https ://sverigesrad io.se/ avsnitt/712016 One option is that I send you a link for a web video Conference call. Another option is that I call you on the phone and your media department may have the oportunity to record a video of your anseers with HD quality that is better to air. Please let me know if you are available and when. Best regards, Johan Bergendorff Science correspondent, Swedish Television (b)(6) From: Date: To: Cc: Subjec t : result s Fauci, Anthony (NIH/N IAID) [E) Thu, 30 Apr 2020 13:31 :50 +0000 Julie.Steen huysen@thomsonreuters .com Greg Folkers Cb)(6) FW: Fauci says leak concern s fueled his W hite House reve lation of Gilead drug Juli e: You di d a goo d j o b in repo rtin g our conversati on last night . Thanks. Best regards, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig ina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6J> Se nt : Thursday, April 30, 2020 8:59 AM To: NIAID COGCORE; NIAID OCGRLeg ; NIAID OD AM Subject: Fauci says leak concerns fueled his White House revelation of Gilead drug results Health News April 30, 2020 / 1:07 AM/ Updated 4 hours ago Faucisays leak concernsfueled his White House revelation of Gilead drug results Julie Steenhuysen 5 Min Read CHICAGO (Reute rs) - Concerns over leaks compelled the top U.S. infectious disease of fi cial to reveal data on Gilead Sciences Inc's experimental drug remdesiv ir, t he first in a scientifically rigorous clinical tr ial to show benefit in t reating COVID-19. National Institute of Allergy and Infectious Diseases Director Dr. Ant hony Fauci attends a coronavirus response meet ing between U.S. President Donald Trump and Louisiana Governor John Bel Edwards in the Oval Office at the White House in Wash ington , U.S., April 29, 2020 . REUTERS/CarlosBarria The dramatic announcement by Dr Anthony Fauci in the Oval Office on Wednesday prompted concerns among scientists that the Trump administration was raising hopes about a coronav irus treatment before sharing the full data with researchers. As a cautionary example of inflating the potential value of a therapy, some pointed to President Donald Trump's repeated endorsements of malaria drug hydroxychloroquine as a treatment , with no evidence that it works . Newer data suggests the malaria treatments may carry significant risks for some sufferers of the respiratory disease caused by the virus. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), which is running the trial, said he took the first opportunity to get the word out that patients taking a dummy treatment or placebo should be switched to remdesivir in hopes of benefiting from it . He expressed concern that leaks of partial information would lead to confusion . Since the White House was not planning a daily virus briefing, Fauci said he was invited to release the news at a news conference with Louisiana Gov. John Bel Edwards(D). "It was purely driven by ethical concerns," Fauci told Reuters in a telephone interview. "I would love to wait to present it at a scientific meeting, but it's just not in the cards when you have a situation where the ethical concern about getting the drug to people on placebo dominates the conver sation ." An independent data safety and monitoring board , which had looked at the preliminary results of the NIAID trial, determined it had met its primary goal of reducing hospital stays. On Tuesday evening, that information was conveyed in a conference call to scientists studying the drug globally. "There are literally dozens and dozens of investigators around the wo rld/' Fauci said. "People were starting to leak it." But he did not give details of where the unreported data was being shared. Several scientists interviewed by Reuters felt the White House sett ing seemed inappropriate for the release of highly anticipated government-funded trial data on the Gilead therapy . They had expected it to be presented simultaneously in a detailed news release, a briefing at a medical meet ing or in a scientific journal, allowing researchers to review the data. Informat ion from various trials of remdesivir has been leaked to media in recent weeks . In a statement on Wednesday, Gilead said the NIAi D's much anticipated trial had met its primary goal, but gave no details . Data in a separate NIAID statement after Fauci spoke detailed preliminary results showing that patients who got the drug had a 31 percent faster t ime to recovery than those who got a placebo, cutting hospital stays by four days. The trial also came close to showing the drug helped people survive the disease, but the data fell just short of statistical significance. "I want to see the full data . I want to understand the statistics. I want to understand the benefit and risk. I want to understand the structure of the study, and all of it," said Dr. Steven Nissen, the chief academic officer at the Cleveland Clinic. "Am I encouraged from what I've heard? Yes, I'm encouraged . But I want to get a full understanding of what happened here, and not get it via a photo opportunity from the Oval Office ." Data Gilead released on its own trial of remdesivir drew less attention, as it did not compare outcomes between those receiving therapy and those who did not . Results from a third study in China suggesting remdesivir failed to help COVID-19 patients were released in the British medical journal the Lancet after review by a peer group of scientists . "That's the only thing I'll hang my hat on, and that was negative ," said Dr. Eric Topol, directo r and founder of the Scripps Research Translational Institute in La Jolla, California. He was unimpressed by remdesivir's modest benefit . "It was expected to be a whopping effect," Topol added . "It clearly does not have that ." At the Oval Office news conference, Fauci compared the study findings to AZT, the fi rst drug to show any benefit against HIV, decades ago. "We know that was an imperfect drug. It was the first step," Fauci said in the interview. "Similar to AZT, it's (remdesivir) the first baby step towards what hopefully will be a number of better drugs that will come in and be able to treat people with COVID-19. (This story has been refiled to correct spelling of "clinical in paragraph one) Reporting by Julie Steenhuysen; Editing by M ichele Gershberg and Clarence Fernandez Our Standards :The Thomson Reuters Trust Principles . 11 11 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAlD , NIB, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 10:20:32 +0000 STEWARTSIMONSO Cb)( Masur, Henry (NIH/CC/CCMD) [E);STEWARTSIMONSON RE:COVID-19 and Haiti From: Date: To: Cc: Subject: Bill: --------------------------------- (b)(6) Work with him. As per our prior conversation and as you know better than anyone, Haiti is struggling and I know that Stewart wi ll do whatever he can to assist you. Warm regards,' Tony From: STEWARTSIMONSON -----------Date: Thursday, April 30, 2020 5:44 AM To: (b)(6) (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E (b)(6)>; STEWARTSIMONSON Subject: COVID-19 and Hait i Masur, Henry (NIH/CC/CCMD) [E] .,,_~~~-=====--~ ~ ------- (b)(6) (b)(6) Dear Dr. Pape: I lead the World Health Organization (WHO) delegation to the United Nations and know of you through Tony Fauci and Henry Masur, (b)(6). For nearly 5 years immediately preceding my appointment at WHO,, I was an technical advisor at Hop ital Sacre-Cawr in Milot and remain in close contact with institution. Because of this, PAHO leadership asked me to join their COVID19 planning discussions related to Haiti. I understand from Henry that you have been appointed by MSPPto coordinate COVID-19 preparedness and response activities. If you have some time available on Friday, it would be good to talk via Zoom or Webex. I can arrange th is and would plan to have the PAHO deputy director as well as other PAHO officials on the line. Would you be available Friday afternoon for such a discussion? If not Friday, anytime over the weekend would also likely work on our end. Thanks so much for conside ring t his. With best regards, Stewart Simonson STEWART SIMONSON W ashington, DC/ N ew York Cb)(6) or (b)(6) Cb)(6)1S) IS) ------ (Switzerland) From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Thu, 30 Apr 2020 01:24:46 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Has anyone tried palivizumab (Synagis) Please respond. From: Rich May (b)(6) Se nt : Wednesday, April 29, 2020 10:21 AM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6) Subject: Has anyone tried palivizumab (Synagis) Good morning Dr. Fauci, Has anyone tried palivizumab (Synagis) on any new COVID-19 patients? Thank you for your time, --- Richard May, MD, PhD, D.H.Sc (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 22:42:24 +0000 Lerner, Andrea (NIH/N IAID) [El FW: NAO repl etion for Covid-19 Please t ake a look and respond if approp riate Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mel Cohen (b)(6) Se nt: Wednesday, April 29, 2020 1:52 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAD repletion for Covid-19 Import ance: High ------ -------- --=~ (b)(6)> Dear Dr. Fauci, Recent research has shown that SARS-CoV - 2 plays havoc with NAOfunction wit hin cells. Coronavirus Infe ct ion and PARPExpression Dysregulate the NAO Metabolome: A Potentially Actionable Component of Innate Immunity: http s://www .bio rxiv.org/content/10 .1101/2020.04.17.047480v3 The Molecular Story of COVID-19; NAD+ Depletion Add resses All Questions in th is Infection : https://www.preprints.org/manuscript/202003.0346/vl Other research has show n that NAD+ levels decline from aging and obesity, both significant factors in Covid-19 severity. But it has also been demonstrated that NAD levels can be replenished through oral administration of nicotin amide ribo side (NR) and nicotinamide mononucleotide (NMN). NR in particular has had several human studies demonstrating its safety and efficacy, and roughly 50 human studies listed on clinicaltrials.gov fo r all manner of disorders. There is at least one anecdotal repo rt of dramatic improvement in a Covid-19 patient after administration of NMN. NMN shows great promise in case studies of humans with COVID-19: https://alivebynature.com/nmn-shows-promise-for-treatment-of-covid-19-in-casestudies/?utm campaign=NMN%20for%20covid%20%28TqFTyz%29&utm medium=email&utm source= Main%20List& ke=eyJrbF91bWFpbCl61CJtZWx/l2.GlzdHJpYnVOZWwuY2EiLCAia2xfY29tcGFueV9pZCl61CJS bWROWFoifQ%3D%3D That article begins with the disclaimer, "There are no human trials that prove effectiveness of any NAO+ boost ing suppfements for preventing or curing COV/0-19." That is a problem . When I see the resources that have been wasted pursuing hydroxychloroquine, I am saddened to learn that there are no clinical trials of nicotinamide riboside as part of a treatment regimen for Covid-19. Can you do anything about getting such a study done? Regards, Mel Cohen (b)(6) From: Date: To: Subject: IN OD Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 22:01:22 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE:ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FOR REVIEW Now FINAL in the OD fo lder. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Wednesday, April 29, 2020 5:03 PM To: NIAID OD AM Subject: ASF----- slides for Business Roundtable, Friday 5-1-2020, 12-1 / FORREVIEW IN OD • This is a zoom call. • I think you will be able to use slides. • I have put in OD a draft "curtain-raiser" set that you could show to kick things off - or use them as TPs if you prefer. • I will update any epi or other numbers tomorrow night • The "ask"is below From: Silverberg , Kristen Date: Tuesday, April 14, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: invitation from BRT ------~ (b)( => Dr. Fauci, First, t hank you for everyth ing you are doing . I have always been grat eful for yo ur public service, but feel part icular ly indebted to you these days. To add to the debt ...Josh and I wanted to see if you would be willing to join a call with Business Roundtable CEOs. We have been doing COVID-19 calls with them every Friday at 1:30pm . Typically, about 100-125 CEOSof large, U.S.-based firms will join. They are all managing and planning for difficult issues around employee and customer safety . They would love to hear from you directly and to ask a few questions . It might also be a good place to deliver any messages you want them to hear. We completely understand if it isn't doable, of course. If you are able, we would love to host you sometime between 1:30pm -2:30pm this Friday (or any Friday on which your schedule wou ld allow it). Best, Kristen From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 15:09:44 +0000 Antho ny Fauci FW: Potential slides fo r Remdesivir presentation Remdesivir bullet slides - FAUCI - FINAL.pptx Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 11:02 AM To rc T. EOP/OVP ___ : Short, ..;_Ma ____ -- (b)'"'"' (~6)'>_________ --------~~ (b)(6),; __ 'Mi ller, Katie R. EOP/OVP' Subject: Potential slides for Remdesiv ir presentation Marc/Katie: Here are 3 slides that I might use in the press briefing. If necessary, I could make the presentat io n without them, but it might be clearer to have them just in case. Thanks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone Cb)(6) FAX: (301 496-4409 --------- (b)( 6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 29 Apr 2020 14:18:44 +0000 Billet, Courtney (NIH/N IAID) [E] RE:two things Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E (b)(6) Date: Wednesday, April 29, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6);; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Stover, Kathy (NIH/NIAID) [El CbH ; Rout h, Jennifer "'.".---:------:-~~==~_;_-~~ (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [El CbH > Subject: ASF: two things ------ --=-= Talked to FDA. They have w ritten (and cleared with Gilead) a new sentence in place of what we had in there about an EUA. Our release has been updated (attached) w it h the sentence highlighted below . ALSO: Bill Hall called me to ask if you had alerted the Secretary to th is (so the press release clearance process isn't t he way he first learns of it). I told him I wasn't sure. If you haven't done so, perhaps you wish to now? As part of the U.S. Food and Drug Administration's commitmentto expediting the development and availability of potential COVID-19treatments,the agency has been engaged in sustained and ongoing discussions with Gilead Sciences regarding making remdesiviravailable to patients as quick ly as possible , as a_p_propriate. Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 10:45:24 +0000 Billet, Courtney (NIH/NIAID) [El Cc: Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [El Subject: RE:please read, Gilead statement From: Date: To: Looks fine. Thanks. From: Billet, Courtney (NIH/NIAID) [E] Date: Wednesday, April 29, 2020 6:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El ; Conrad, Patricia (NIH/NIAID) [El ; Marston, Hilary (NIH/NIAID) [El ; Routh, Jennifer (NIH/NIAID) [El ; Stover, Kathy (NIH/NIAID) [El ; Lane, Cliff (NIH/NIAID) [El ; Erbelding, Emily (NIH/NIAID) [El Subject: ASF: please read, Gilead statement FYI- this will go out before markets open this morning: GILEAD SCIENCES STATEMENT ON POSITIVE DATA EMERGING FROM NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES' STUDY OF REMDESIVIR Foster City, Calif., April 29, 2020 - Gilead Sciences. Inc. (Nasdaq: GILD) is aware of the positive data emerging from the National Institute of Allergy and Infectious Diseases' (NIAID) study of remdesivir. We understand that the trial has met its primary endpoint and that NIAID will provide detailed information at an upcoming briefing. In addition to the NIAID trial, Gilead expects to share additiona l remdesivir data from the company's open-label Phase 3 SIMPLE trial in patients with severe COVID19 disease shortly. This study will provide information on whether a shorter, 5-day duration of therapy may have simi lar efficacy and safety as the 10-day treatment course evaluated in the NIAID trial and other ongoing tria ls. Gilead expects data at the end of May from the second SIMPLE study evaluating the 5- and 10-day dosing durations of remdesivir in patients with moderate COVID-19 disease. Gilead will continue to discuss with regulatory authorities the growing data set regarding remdesivir as a potential treatment for COVID-19. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Ap r 2020 03:09:03 +0000 To: Berkowitz, Avrahm J. EOP/WHO Subject: RE:Jared Kushner Defends Dr. Fauci After Fox News Host Criticises Top Coronav irus Task Force Expert Thanks , A vi. -----Original Message----From: Be rkowitz , Avra hm J. EOPfWHO (b)(6) Scot : T uesday , April 28, 2020 I 0:00 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH > Subject: Jar ed Kushn er D efend s Dr . Fauc i After Fox News Host Criticises T op Coronavirus Task Force Expert ------. ;;-s-r;o= Just wanted to share an article- all the best! Avi htt:ps://www.newsweek.conv'jared-kushner-defends-dr-fauci- fox-news-host-Iittle-tough-I 500339 Sent from my iPhone From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 29 Apr 2020 03:08:36 +0000 To: Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E);Routh, Jennifer (NIH/NIAID) [El;Erbelding, Emily (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: RE: DRAFTNIAID statement on remdesivir , ACTT 2 Attachments: SHORTENEDNIAID statement NEW NEW -with Fauci edits .docx See my minor edits. (b)(5) From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 10:40 PM To: Folkers, Greg {NIH/NIAID) [E) (b)( •>; Fauci, Anthony {NIH/NIAID) [E) CbH6>>;Routh, Jennifer (NIH/NIA ID) [E] CbH6);Erbelding, Emily (NIH/NIAID ) [E) CbH6l> ; Lane, Cliff (NIH/NIAID ) [E) (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)( > Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: DRAFTNIAID statement on remdes ivir, ACTT2 ------~ = From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 10:02 PM To: Folkers, Greg {NIH/NIAID) [El (b)(6);Fauci, Anthony (NIH/NIAID) [El (b)(6)v>; Routh, Jennifer (NIH/NIAID) [El (b)(6)>;Erbeldlng, Emily (NIH/NIAID) [E) CbH6)>; Lane, Cliff (NIH/NIAID ) [E] CbH6>> ; Marston , Hilary (NIH/NIAID) [E] Cb)( > Cc: Conrad, Patricia (NIH/NIAID) [E) Cb)( v> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 ------- -== (not sure what happened with spacing). Cliff- I got your suggestion too . I'll blend yours, mine, and Gregs and send a clean new one shortly. From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 10:01 PM To: Folkers, Greg (NIH/NIAID) [El (b)( >; Fauci, Anthony (NIH/NIAID) [E] (b)(6b ; Routh, Jennifer (NIH/NIAID) [El< CbH6)>; Erbelding, Emily (NIH/NIAID) [El (b)(6)>;Lane, Cliff (NIH/NIAID ) [El (b)(6); Marston , Hi la ry_(_ N_ I H.., /_ N-IA-1D ...)...[-E)-::::::===:::!...:~___.:.~ (b ~)~( > -------~ = Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 I took a crack at a revision as well. We can blend these. From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Tuesday, April 28, 2020 9:57 PM To: Fauci, Anthony (NIH/NIAID) [El .ef-----~ (b~)( =6J; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIA ID) [El (b)(6); Erbelding, Emily (NIH/NIAID) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [E] (b)(6):,. Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: RE: DRAFTNIAID statement on remdesivir, ACTT 2 Here is my suggested edit to the short version. ------- From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 9:21 PM To: Routh, Jennifer (NIH/NIAID) [El (b)(6); Billet, Courtney (NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID ) [El (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6); Marston , Hilary (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El (b)( > ------~~ ------- Subject: FW: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High Th anks for all your work. ange this. -------- From: Billet, Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7:29 PM To: Fauci, Anthony {NIH/NIAID) [E] -------= (b)(6) = (b)(6)> Cc: Routh , Jennifer {NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIA ID) [El (b)(6)>; Conrad , Patricia (NIH/NIAID) [El (bH >; Folkers, Greg (NIH/NIAID) [El (b)( >; Erbelding, Emily (NIH/NIAID) [El (b)(6)>; '.":"":":"::-'.'::"":-:-:::":--:::====--~~ Lane, Cliff (NIH/NIA ID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [El (b)(6) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance:High There are two versions for your consideration here, as discussed. From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:53:28 +0000 Lane, Cliff (NIH/NIAID) [El RE: Bullets Rendesivir bul let slides - FAUCl.pptx I added another bullet. From: Lane, Cliff (NIH/NIAID) [El _______ Date: Tuesday, April 28, 2020 9:51 PM To: Fauci, Anthony {NIH/NIAID) [El______ Cb _H_6) """ (b"""" )(=6) Subject: Re: Bullets Graph inserted. From: Anthony Fauci (b)(6 )> Date: Tuesday, April 28, 2020 at 9:47 PM To: "Lane, Cliff (NIH/NIAID) [E]" Subject: RE: Bullets -------=-:~ -------- (b)(6) ,> I made some m inor changes -------- From: Lane, Cliff (NIH/NIAID) [El Date: Tuesday, April 28, 2020 9:27 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Bulle ts --------- For comment (b)(6) (b)(6J> From: Fauci, Anthony (NIH/N IAID) [El Wed, 29 Apr 2020 01:50:16 +0000 Lane, Cliff (NIH/NIAID) [El RE: DRAFTNIAID statement on remdesivir, ACTT 2 ACTT 2 NIAID statement CB KSEEHM HCLl - with minor edits.docx Date: To: Subject: Attachments : (b)(5) I made some minor edits. From: Lane, Cliff (NIH/NIAID) [E] ______ (b _)_(_ > Date: Tuesday, April 28, 2020 9:44 PM To: Fauci, Anthony {NIH/NIAID) [E] -------=(b=)(=6) Subject: Re: DRAFTNIAID statement on remdesivir, ACTT 2 Attached for consideration. From: Anthony Fauci (b)(6)> Date: Tuesday , April 28, 2020 at 9:21 PM To: "Routh, Jennifer (N IH/NIAID) [E]" ------- [E]" -== (b)(6)>, (b)(6)>, "Folke rs, Greg (NIH/NIAID) [El" "Erbelding, Emily (NIH/NIA ID) IE]" (b)(6)>, Hila ry Marston --------Cc: "Conrad, Patricia (NIH/NIAID) [E]" "Billet, Courtney (NIH/NIAID) (b)(6) (b)(6), " Lane, Cliff (NIH/NIAID) [E]" --========:e:=~ (b)(6)> Subject: FW: DRAFT NIAID st atement on remdesivir, ACTT 2 (b)(5) Thanks fo r all your work. (b) (5) -------------------------- (b)(5) Please change t his. ------- From: Billet, Courtn ey (NIH/NIAID) [El (b)(6)> Date: Tuesday, April 28, 2020 7:29 PM {NIH/NIAID) [El (b)(6)> Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6) ,; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El~---:~-=== (b =)=(6) ::!.. >..:.. ; _Er~b_el~ding, Emily (NIH/NIAID) IE] (b)(6); Lane, Cliff (NIH/NIAID) [E) (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6) To: Fauci, Anthony ------= = Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 29 Apr 2020 01:21:27 +0000 To: Routh , Jennifer (NIH/NIAID) [E);Billet, Courtney (NIH/NIAID) [E];Greg Folkers (GFOLKERS@niaid.nih.gov);Erbelding, Emily (NIH/NIAID) [El; Lane, Cliff (NIH/NIAID) [El;Marston , Hilary (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: DRAFT NIAID statement on remdesivir, ACTT 2 Attachments: ACTT 2 NIAID statement CB KSEE HM.docx, SHORTENED NIAID statement .docx Thanks for all our work. However --------------------------this. Cb)(5). Please change (b)(6) From: Billet , Courtney (NIH/NIAID) [El Date: Tuesday, April 28, 2020 7 :29 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Routh , Jennifer (NIH/NIAID) [E) (b)(6h; Stover , Kathy (NIH/NIA ID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6); Folkers, Greg --------- -------=-:-= ":'----:-------:--:--:-.:==~ (NIH/NIAID) [E)~-~-==== Lane, Cliff (NIH/NIAID) [E] (b)(6)> (b= )(= 6l->:..... ; E~r_ be~lding, Emily {NIH/NIAID) [E) Cb)( >; Marston, Hilary (NIH/NIAID) [E) Subject: ASF: DRAFTNIAID statement on remdesivir, ACTT 2 Importance: High There are two versions for your consideration here, as discussed. (b)(6)>; From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Wed, 29 Apr 2020 00:56:02 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus info about a program that can help. BCA_id_Vl (wecompress.com) .pdf Please take a look and respond if appropria te -----Original Message----From: Alex Holbus .:-------(b ~)~(=6) Scot: Tuesday , April 28, 2020 6:59 PM To: Fauci , Anthony (N1H/NIAlD) [E] ------ --,;;..,....,-= CbH > Subj ec t: Cor onavirn s info about a pr ogram that ca n he lp. Dear Dr Fauci lt's a pleasure to send you this email my name is Alex Holbu s I am from the UK I currently live in Serbia or ex Yugoslavia. l am a Economist and Humanitarian. I can talk about my Biography but. at this time the subject I want to share with you I much more important. l n January 2016 1 sent a letter to Mr Trump (b) (6) telling him that 1was happy that he will bring change to America and the world and that ifhe needed my expertise that I wou ld help your count ry and the world. As 1 have not got any responses from him nor his people I can see that he might not be interes ted. But as I have been following you over the media and be read ing about your carrier as a Doctor I believe you know wha t your doing and would like to take this opportuni ty to help you and your country at this time when it' s the worst then ever before in the modem world. I have a program that can help with the co ronavirus in the way of identifying people and following there movement that can help you collect data faster and more suffic ien t. The progr am is based on an app so every one can use it. Countries in Europe are starting to use it by the end of May the Europe Union has made it mandatory that all member state, need to use it and the future members like Serb ia. So you w ill see attached a presentation about the program and if you or your country is interes ted please let me know and I will put you in contact with the company making this program. I did not send this email to you so we make money on people it's to help I ju st wanted to help. I will be contacting my contacts in the USA from Thursday morning but first 1wanted to talk with you and give you the opportunity to see if Mr Trump would interested in this program for your country. Tf nothing com es back from you anyway my friend and contact in the USA will talk with the white house but l want ed to do it the proper way by talking to you as you are the main medical person in the USA for the coronavirus . Anyway wish you and your country all the best and that the world will become a better place after this epidemic is over . Jt's one life one world one human we arc all one on this planet no one is bigger or better the all of us as human ity as one. Kind regards Alex Holbus Director at Real Five Compan y. From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 28 Apr 202017 :41:52 +0000 To: (b)(6) RE:worrisome Subject: Yes. Please call t o th eir att enti on. ___________ Cb _>_<6> It is merely a nasa l swab Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------- From: Date: Tuesday, April 28, 2020 10:32 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: worrisome (b)(6) (b=)(=6) From today's Medscape . https://www.medscape.com/viewarticle/929407?nlid=135287 MSCPEDIT&uac=71367AK&impl0=2361940&faf=1 5653&src=wnl newsalrt daily 200427 Older adults with COVID-19, the illness caused by the coronavirus , have several "atypical " symptoms, complicating efforts to ensure they get time ly and appropriate treatment, according to physicians. COVID-19 is typically signaled by three symptoms: a fever, an insistent cough and shortnes s of breath. But older adults - t he age group most at risk of severe complications or death from t his cond ition may have none of these characte ristics. Instead, seniors may seem "off" - not acting like themselves - early on afte r being infected by the coronavirus . They may sleep more than usual or stop eating. They may seem unusually apathetic or confused, losing orientation to their surroundings. They may become dizzy and fall. Sometimes, seniors stop speaking or simply collapse. (b)(6) Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 2020 17:39:34 +0000 Janet Tob ias;Conrad, Patricia (NIH/NIAID) [El RE: Riding along tomorrow am From: Date: To: Subject: OK Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Tuesday, April 28, 2020 12:46 PM To: Fauci, Anthony (NIH/NIAID) [El -----(b)(6) -------- (b =)(6)1 •>; Conrad , Patr icia (N IH/NIAID) [El Subject: Riding along tomorrow am Hi Tony and Patty : Would it be ok to do the 6:45 am ride to NIH tomorrow? We would also get there early to do one more paper throw. And last night was great! Janet From: "Fauci, Anthony (NIH/NIAID) [E]" <______ Date: Sunday, April 26, 2020 at 4:30 PM Cb> _<6) _> To: Janet Tob ias Subject: RE: Quick question My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M .D. From: Date: To: Subject: Attachme nts: Auchincloss, Hugh (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E] Tue, 28 Apr 2020 15:50:24 +0000 NIAIDODAM FW: Invitation from the Investment Community Letter of invitation_Dr. Anthony Fauci from UBS Investment Bank (1).pdf I don't think so. --------------------- -=~ From: Elizabeth Haenle Date: Tuesday, April 28, 2020 11:36 AM To: Fauci, Anthony (NIH/NIAID) [El (bH6J> Subject: Invitation from the Investment Community Dear Dr. Fauci, I am t he co-founder of SAGEWor ldwide, a global speaker and consulting company. I am reaching out on behalf of one of my partners, Robert Karofsky, Co-President of UBS Investment Bank, with an invitat ion to join the UBS Global response to Covid-19 in a live streaming moderated discussion on May 18. Alternatively your conversation could be pre-recorded to accommodate your busy schedule. At this critically important time in our nation's history, the investment community wants to help our nation fight Covid-19 and use our country's economic engine to find a cure and solutions for Covid-19. They also are thinking through how to help our nation's businesses going forward. Your expertise is important to this conversation . By way of background, I served in the White House for eight years in the Bush Administration as the Social Secretary to Vice President Cheney. In that capacity, I had the privilege of curating a range of discussions with global thinkers and thought leaders on the world's most pressing topics. At SAGE,we bring t hat level of excellence t o our business partners as we help curate discussions that have an impact on public awareness and investor sentiment, which is part icular ly impor tant as the U.S. responds t o Covid-19. Participants at the UBSGlobal Healthcare Conference provide critical funding to pharmaceuticals and healthcare research and are the businesses on the frontline of the Covid-19 healthcare response. Attached please find an invitat ion from UBS with further details of the event. I welcome the opportunity to hear from you at your earliest convenience, and thank you for your important work and dedication to our country's we ll being over the course of your distinguished career and service at NIAID. Warmest regards, Elizabeth Haenle Co-Founder, SAGEWorldwide Phone: (b)(6) Attachment 1 Elizabeth Haenle CmH!l. Co-founder and Presjdeot ------E: --------M: (b)(6) (b)(6) W: SAGEworldwide.com cotm This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This message contains confidential information and is intended only for the individual named. If you are not the named addressee you should not disseminate, distribute or copy this e-mail. Please notify the sender immediately by e-mail if you have received this e-ma il by mistake and delete this e-mail from your system. If you are not the intended recipient you are notified that disclosing, copying, distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Date: To: Subject: Au chincloss, Hugh (NIH/ NIAID) [E] on beh alf of Fauci, Ant hony (NIH/NIAID) [El Tue, 28 Apr 2020 14:46:56 +0000 NIAID ODAM FW: HIGH SCHOOL MUN CONFERENCE For d iscussio n From: Dane Cohn (b)(6)> Date: Tuesday, April 28, 2020 10:44 AM -----~= To: Fauci, Anthony (NIH/ NIAID) [El (b)( >; Barasch, Kimberly (NIH/ NIAID) [C] (b)(6); Conrad, Patricia (NIH/NIAID ) [El (b)(6) ; Fauci, --:---:----:----:--:--:-;::::::::::c.:..._ _ ___,:__~= An t ho ny (NIH/ NIAID) [E] (b)( 6) Subject: HIGH SCHOOL M UN CON FERENCE Dear Dr. Anthony Fauci , My name is Dane Cohn , and I am an (b)( 6). I have often listened to your inspiring words on the news and followed your assiduous work to help us through this pandemic. Our school participates in Model UN, an event in which high school studen ts represent various countries in debates on international issues from the past and present. Colorado's final Model UN conference was canceled , so our school (bH6) ) decided to host an online conference for the whole state of Colorado and beyond . Our team would like to formally invite you to give a short address (be it pre-recorded or live onlin e) to the student s during our opening ceremony . ----------- We hope that our conference will inspire the youth of our nation and the world to stan d up and fight for our futu re rather than resign their aspirations to lockdown . We host this conference because we see the importance of keeping our academ ic passions going while staying safe within the confines of our homes . We host this conference because we want to contribut e to the fight again st COVID -19 - money raised from our conference will go towards buying masks, food, and other resources for those wh o need it most. This is why we ask you , a hero during this troubling time, to speak to the students of our confer ence, who not only include the youth of Colora do , but also the youth of our country and w orld. Any type of address would be greatly and wholeheartedly appreciated. If your address is pre-recorded , we would appreciate it if we could receive it by May 1st, as our conference is the morning of May 2nd . We believe you can bring true inspiration into our hearts and minds . We know you are very busy, but if it were at all possib le to share with us even a short 2-3 minute pre-recor ded greeting and message to the students participating in this Model UN conference , it would be truly inspirational. Thank you so much for your time , we hope to hear from you soon . Most Respectfully, Dane Cohn and the entire --------- (b)( 6) Model UN Team From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 28 Apr 202011 :25:09 +0000 Haskins, Meli nda (NIH/NIAID) [El Conrad, Patricia (NIH/NIA ID) [El RE: Please advise LHHS Hearing w / Dr. Fauci -- Wednesday, May 6 8:30 AM would be good. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Haskins, Mel inda (NIH/NIA ID) [El Date: Tuesday, April 28, 2020 7:08 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Please advise LHHS Hearing ---------- ------~= (b) ( '> (b)(6)> (b)(6):> w/ Dr. Fauci -- Wed nesday, May 6 Let me know when you ' d like me to call please. CbH > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 28, 2020 7:04 AM To: Haskins, Melinda (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Re: Please advise LHHS Hearing ------- -,a-s-r= (b)(6)> (b)(6) w/ Dr. Fauci -- Wednesday, May 6 Let us chat by phone t his morning On Apr 28, 2020, at 5:51 AM, Haskins, Melinda (NIH/NIAID) [E] w rote: (b) ( > We do not know if the Dela uro hearing would be remote. The Senate HELPone would be in person w it h some form of social distanc ing. Sent from my iPhone On Apr 27, 2020, at 10:36 PM, Fauci, Anthony (NIH/NIA ID) [E) (b) (6) wro te : -------- E should make sure that we schedule it at a time of day that does not conflict with the COS visit. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Se nt : Monday, April 27, 2020 8:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Please advise LHHSHearing w/ Dr. Fauci -- Wednesday, May 6 ------ --=-<= This is the day of the VIP visit-whoever it is. VP or COS.Pis advise. And not sure if these are I person or not. I suspect remote right?? Sent from my iPhone Begin forwarded message: From: "Haskins, Melinda (NIH/N IAID) [E]" (b)(6) Dat e: Apri l 27 , 2020 at 8:10:52 PM EDT To: "Conrad, Patricia (NIH/NIAID) [E]" (b) ~ > Cc: NIAID OCGRLeg , " Billet , Courtney (NIH/NIAID) [E)" (b)( , "Harper, Jill (NIH/NIAID) [E]" (b)(6) Subject: Please advise LHHS Hearing w/ Dr. Fauci -- Wednesday, May 6 Patty, See below . Another hearing. Thank you, Melinda Sent from my iPhone Begin forwarded message: From: " Hallett, Adrienne (NIH/OD) [E]" (b)(6) Dat e: April 27, 2020 at 7:57:36 PM EDT To: "Haskins, Melinda (NIH/NIAID) [E]" (NIH/NIAID) [E)" (b)(6)>, "LaMontagne, Karen (NIH/OD) [E]" (b)(6)>, "Higgins, Lauren -( N - I-H/-:0-D"'."" )-:[E-:] ,:-:: ' ====~ (b ~) ~( > -------- Subject: Fwd: LHHS Hea ring w / Dr . Fa uci -W e dnesday, May 6 Guess they really are coming back. Begin forwarded message: From: "Steigleder, Stephen" (b)(6) > Date: April 27, 2020 at 7:41:56 PM EDT To: "Hallett, Adrienne (NIH/OD) [E]" (b) ( > Subject: LHHS Hea ring w/ Dr. Fa uci - - W ednesday, Ma y 6 Hi Adrienne, I hope you're doing well. I'm reaching out because Chair Delauro would like to invite Dr. Fauci to a hearing next Wednesday, May 6, with the House LHHSappropriations subcommittee . The focus of the hearing, not surprisingly, would be COVID-19. Members of the subcommittee wo uld very much like to hear from Dr. Fauci on anything related to COVID-19, but I think the main topics would be: • Mitigation and Testing; and • Progress on vaccines, therapeutics, and diagnostics, as well as necessary preparations to manufacture and disseminate a vaccine once it is ready. Chair Delaura is flexible about a starting time for the hearing on Wednesday , so she would be happy to accommodate a t ime that works for Dr. Fauci's schedule. Please let me know as soon as possible, so we can plan accordingly. Thanks so much, Stephen Stephen Steigleder House Appropriations Committee Labor/HHS/Education Subcommittee From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 28 Apr 2020 00:22:50 +0000 (b)(6) To: Subject: Attachments : FW: Remdesiv ir--good news 20-0006 _DSMB_primary _analysis_report_for _OMI D.pd f Cb _>_<_ > From: Erbelding, Emily {NIH/NIAID) IE] _______ Date: Monday, April 27, 2020 8:05 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""(6) = > Subject: Remdesivir--good news Ton'l,,_______________________________ --~ (b) (5) Emily Emily Erbelding, M .D., M.P.H. Director, Division of Microb iology and Infectious Diseases NIAID/N IH 5601 Fishers Lane Rockville, MD 20852 Tel: (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) Mon, 27 Apr 2020 22:56:59 +0000 Fauci, Anthony (NIH/NIAID) [E) [El FW: Brown et al submitted .pdf, NIH Presentation final.pp tx, prepr ints202002.0147.v2 (1) .pdf, Mosaheb et al 2020.pdf Email from Dani Bolognesi. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Dani Bolognesi , Ph.D. ----------------= -------- = (b)(6)> Date: Monday, April 27, 2020 6:09 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6l;Barasch, Kimberly (NIH/NIAID) [C] (b)( 6) Subject: FW: Kimberly: Please see that this reaches Tony as per our call today. TX in advance. Dani Hi Tony: In advance of getting together wi t h you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) (b) (4), (b) (5) We are prepared to discuss this with you and your team at any time that is convenient for you. As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEx as an initial step . Many thanks for the opportun ity to share this with you ! All the very best, Dani (b)(6) Best, Dani Sent from Dani Bolognesi From: "Dani Bolognesi, Ph.D." Date: Monday, April 27, 2020 at 2:53 PM To: "Matthias Gromeie r, M.D." (b)(6)> -----------~~ Subje ct : Please review this draft email to Tony--TX Matthias: Please review and edit the proposed email to Tony. (b)(6) Dani Hi Tony: In advance of getting together with you and your team, I am forwarding a short presentation for you guys to look at. The key elements are follows: (b) (4). (b) (5) We are prepared to discuss this with you and your tea at any time that is convenient for you . As you may know, we are locked down here in the Research Triangle until May 15. If it makes sense, we could arrange a WebEX as an initial step . All the best, Dani Best, Dani Sent from Dani Bolognesi The infor matio n in this electronic mail is sensitive, protected information inte nded only for the addressee(s). Any othe r person, including anyone who believes he/she might have received it du e to an address ing error, is requeste d to notify the sender imm ed iate ly by return electronic mail, and to delete it without further reading or retention . The information is not to be forwarded to or shared unless i n compli ance with Duke Health policies on confidentiality and/o r w ith th e approva l of the sender. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 22:17:19 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM RE: COVID/ Transportation Impacts Ok. Let us discuss forwarding to CDC> Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Ins titutes of Health Bet hesda , MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E-mail (b) (6) The informati on in this e-ma il and any of its attachme nts is confidential and may contai n sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. l f you have received this e-mail in erro r please inform the sender and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Diseases (NlAI D) shall not accept liability for any stateme nts made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Folkers, Greg (NlH/NlAID) (E] Date: Monday , Apri l 27, 2020 6:15 PM To: Fauci, Anthon y (NTH/NlAID) [E] --------= Subject: RE : COY ID/fransportation Impacts --------- (b)( --------- (b)( ; NJAID OD AM this seems like CDC issue They address some of the issues here: What Ridesbare, Tax i, Limo, and other Passenger Driv ers -for-Hire Need to Know about COVJD - 19 https://www.cdc.gov / coronavi ms/ 20 I 9-ncov / community / orga nizati ons/ ridesbare-drivers -for-h ire.htm I Communication Too lkit for Transpo1tat ion Parto el'S to Inform Road Travelers Monday, April 27, 2020 https: //www .cdc.gov / coronav irus/2019 -ncov /travelers /transportat ion-toolkit.htm l Cleani ng and Disinfect ion for Non-eme rge ncy T ranspo rt Vehicles Tuesday, Ap ril 14, 2020 https: //www .cdc .gov/ coronav iru s/? 019-ncov / community /orga nizations /d isin fectinQ.-transport-vch icles. h tm I -----Original Mcssage----From: [E] Conrad, Patricia (NIH/N IAID) [E] ....______ Date: Monday, Apri l 27, 2020 6:05 PM To: NIAID OD AM Subject: FW: COVID/Transportation Impacts -----Original Message----- (b)(6) ___, On Beha l f OfF auci, Anthony (NIH/NIA ID) From: Anthony Foxx Date: Monday, April 27, 2020 4:39 PM To: Fauci , Anthony (NIH/NIATD) [E] (b)(6) > -------~~ --------- (b)( Subject: COVID/Transportation Impacts Dr. Fauci: Thi s is Anthony Foxx, immediate former US Transportation Secretary, and Tgreat ly enjoyed our interactions (brief tho ughts they were) during my time in the last Admi nistrat ion. I write to request your help in advising the transportation community about how to manage through the present crisis, particularly as some areas are easing restrictions. I would welcome an opportunity to join you in a Q/ A, which could be valuable for rideshare companies (b) (6l), transit agencies, airlines etc. I would think that a I0-15 minute chat would do wonders. That said, I know you are terribly busy and have so many things to do but would appreciate any opportunityto help you get important infonnation out. This could be pulled together rapidly and done within the next week or so, Thanks for your attention to this matter. All my best, Anthony. Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 22:00:13 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Update - White House Coronavirus Task Force Mee t ing - 4.28.20 FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:57:57 +0000 Lusso, Paolo (NIH/N IAID) [El RE:Covid t hrombi From: Date: To: Subject: Than ks, Paolo . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------.....,....,= --------, (b)(6) From: Lusso, Paolo (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Kovacs, Joseph (NIH/CC/CCMD) (E] (b)(6) Masur, Henry (NIH/CC/CCMD) [E] (b)( ; Lane, Cliff (NIH/':':" N"."." IA ':""'. l':"' D:-"". )[ :'::' E:. ] ====::..,... (b,...., )( ,:;;, 6)> -~"."':=======~~ -------- Subject: Re: Covid thrombi Dear Tony, I talked with Dr. Viecca this morning who shared additional info rmation about his pro tocol. They started fr om the pathologica l observation that all patients dying of Covid- 19 pneumo nia had diffuse pulmonary microthrombosis . Since th ey detect ed almost exclusively white th rombi, they reasoned that they had to block platelet activation/aggregation, whi le heparin would be ineffective at that stage. Thus, they t reated a first group of five critica l pati ents with potent anti-aggregant t herapy (Tirofiban/ Aggrastat) and apparen t ly in all of t hem the p02 started to rise within less than 2 hours, they got off the vent ilators and went on to full recovery. Viecca is an intervent io nal cardiologis t (b)( 4) I sent copy of his protocol and contact information to Joe. Let m e know if I can be of any further help. All the best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmuno regulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: (b)(6) (personal) (b)(6) (lab) Fax: (301) 480 -5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. The Natio nal Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made tha t are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ******************************~ From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 21:57:23 +0000 -----~~ Collins, Francis (NIH/OD) [El Mascola, John (NIH/VRC)[E) Subje ct: FW : Revised Slid es Vacci ne Development Slides Revised Draft 042720.pptx ------- Attachment s: (b)(6) Pleas respond for both of us. I already cc' d you on an em ail t hat I sent to John wi t h a m inor comm ent about slide #2. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended re cipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Marks, Peter Date: Monday, April 27, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [El ------~~ -------- (b)( 6) -------- Cc: M ascola, John (NIH/VRC)[E] Subje ct : Revised Slides (b)(6) (b)( (b)( >; Collins, Francis (NIH/OD) [El > Dear Francis and Tony, Apologize that t he prior slides were too busy. John conveyed that message. Pleasesee t hese versions t hat may be more along the lines that you are loo king for . (b) (5) Best Regards, Peter From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 21:54:37 +0000 Schwetz, Tara (NIH/OD) [El RE: Flagging NIH Media Product for Release Tomorrow You could play the role in the movie of my medical school girl friend, which wou ld give you the possibility of working with Brad Pitt Q Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Schwetz, Tara (NIH/OD) [E] (b)(6) Date: Monday , Apri l 27, 2020 5:49 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Flagging NIH Media Product for Release Tomorrow ------~~ Now, you also have the answer to who would play you in a mov ie! © Tara A. Schwetz , PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- --,;-,-= ----- From: "Fauci , Anthony (N IH/NIAID) [E]" CbH6) Date: Monday, April 27, 2020 at 5:46 PM To: Tara Schwetz (b)( Subject: RE: Flagging NIH Media Product for Release Tomorrow Thanks, Tara. Pitt was amazing. One reviewer of the SNLshow said that Pitt looked "exact ly like me". That stateme nt made my year. (Q) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used by anyone who Is not the orig inal Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Schwetz, Tara (NIH/OD) [El (b)( > Date: Monday, April 27, 2020 5:11 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Marston , Hilary (NIH/NIAID) [E] (b)(6) ; Conrad, Patricia (NIH/NIAID ) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Myles, Renate (NIH/OD) [El (b)( ; Walsh, Elizabeth (NIH/OD) [El (b)(6) --------, .....,....,= Subject: Flagging NIH Media Product for Release Tomorrow Tony, Please see below and attached a ti me-sensit ive COVID-19 item for your awareness and sharing wit h t he rema inder of the Task Force, as appropriate. The plan is to release this tomorrow. Item 1: Title : Rapid Acceleration of Diagnostics (RADx) Initiative Activity Type : Funding of new research program Summary: W ith a (b)(5) investment from fede ral st imulus fund ing, RADx initiat ive w ill infuse fund ing into early innovation techno logies to speed deve lopment of rapid and widely accessible COVID-19 tes ting. At the same time, NIH will seek opportunit ies to move more advanced d iagnost ic technolog ies swiftly through the development pipeline towa rd commercialization and broad availabil ity. As part of the init iat ive, NIH is urging scientists and inventors with a rapid test ing tec hnology to compete in a nat ional COVID-19 test ing challenge for a share of up to $500 million over all phases for further deve lopmen t. The goal is to add tens of m illions per month of accurate and easy-to-use tests to all Americ ans by Fall 2020. Impact on COVID-19 Pandemic Response: RADx will accelerate the development, validation, and commercializ ati on of innovative new testing methods that can be deployed in point-of-care and home settings. These technologies are urgently needed to guide and inform safe return to work, schoo l, and life activities. Office : National Institute of Biomedical Imaging and Bioengineering Action Date: Solicitation announcement April 28, 2020 Type of Action: Research Program Award Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Do let me know if you have any questions. (Also, Brad Pitt?! Wow, that was a real ly nice shout out/thank you.) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ P: (b)(6) I M: (b)(6) From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Ap r 2020 21:48:46 +0000 Birx, Deborah L. EOP/NSC Redd, Stephen (CDC/DDPHSIS/OD);Hahn, Stephen Flagging NIH l'vledia Product fo r Release Tom orrow 2020 -04-27_COVID-19Week lyReport _ NIBIB OD_tas .docx Deb: As an FYI. This is an initia ti ve fr om NBIB/N IH on developm ent of POC diagnost ics for SARS-CoV-2. Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: (NIH/N IAID) [El Subject: Looks fine. Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 21:39:57 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASF REVIEW:Draft PR re: SARS-CoV-2 incidence in children Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 27, 2020 4:57 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb _> _C6) _, ; Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Subject: FORASF REVIEW:Draft PR re: SARS-CoV-2incidence in children ------= = Hi Dr . Fauci, Please find at tached fo r your review a draft release about the launch o f t he Human Epidemiology and Response to SARS-CoV-2(HEROS)study, which is intended to help determine t he percentage of children infected with SARS-CoV-2and the percentage of infected children who develop COVID. In addition , the study will examine whether rates of SARS-CoV-2infection differ between children who have asthma or other allergic conditions and children who do not. Your draft quote is as follows : 11 0ne interesting feature of this novel coronavirus pandemic is that very few children have become sick with COVID-19 compared to adults," said NIAID Director Anthony S. Fauci, M.O. "Is this because children are resistant to infection with SARS-CoV-2, or because they are infected but do not develop symptoms? The HEROSstudy will help us begin to answer these and other key questions." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7Al 7E Bethesda, MD 20892 Phone: (b)(6) E-mai l (b) (6) NIAID Media Line: (301) 402-1663 From: Date: To: Cc: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 21:04:24 +0000 Auch incloss, Hugh (NIH/N IA ID) [C) Conrad, Patricia NIH/NIA ID [E);Jean W Pape ---------~~ ----------- (b)( 6) (b) (4) Subject: Attachment s: Hugh: (b) (6), (b) (4) Please t ake care of it. Than ks, To ny Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not th e orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------------------------=-=--:-= --------- From: Date: Monday , April 27, 2020 3:0 1 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b) (4) (b)(6) (b)(6) To ny , (b) (4), (b) (6) Best, Bill JEAN W ILLIAM PAPE, M D Howard and Carol Holtzmann Professor of Clinical Medicine, Center for Global Health, Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, USA 402 East 67th Street, New York, NY 10065 Tel (Office) (b)(6) Director, Les Centres GHESKIO, 33, Blvd. Harry Truman, Port-au-Prince, Ha'iti. Tel (Office): Voip: (b)(6) (b)( From: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Date: Mon, 27 Apr 2020 16:09:04 +0000 To: NIAIDODAM Subject: FW: The National Organization of Ital ian Americans in Film & Television (NOIAFT) - Int erview Request Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor National Inst itut e of Allergy and Infectious Diseases The National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensi tive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Taylor Taglianetti Date: Monday, April 27, 2020 12:03 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [El ... Cc: Fauci, Anthony (NIH/NIAID) [El Subject: The National Organization of Italian Americans in Film & Television (NOIAFT) - Interview Request ________ .:=========~~ Dear Dr. Fauci, I hope this email finds you wel l. My name is Taylor Taglianetti and I am the founder of the Nationa l Organization of Italian Americans in Film & Television (NOIAFT). Our organization is so very proud of the work you are doing for our country and sends tremendous thanks for the hope and reassurance you have instilled during these trying times. It would be an honor to conduct a short inte rview with you. Our organization includes many young Italia n Americans breaking into the entertainment industry and with the coronavirus dramatically impact ing our field, I'd love to ask you a few questions about what the future of the entertainmen t business looks like. We'd be happy to send the questions in advance for your approval. If you don't have time for a phone call, the questions can be answered via email at your leisure . Thank you for your time and consideration. Sincerely, Taylor Taglianetti Founder, The National Organization of Italian Americans in Film & Television (NO/AFT) (347) 686-4968 www.noiaft.org taylor@noiaft.org (bX5)-PCl1 (bX5) -PCP. (bXS) - PCP. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 14:19:38 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Media query: CNN, re: ASF'sNASweb briefing on Saturday I was referring only to animal (macaque) models. I never said t hat it loo ked good in humans . Human clinical trials are ongoing to answer t hat question . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: Monday, April 27, 2020 9:30 AM To: Fauci,Anthony (NIH/NIAID) [E]------= (b) ""(=6J> Subject: Fwd: Media query: CNN, re: ASF'sNASweb briefing on Sat urday Pis advise Sent from my iPhone Begin forwarded message: --------- From: "Leifman, Laura (NIH/NIAID) [E]" Date: April 27, 2020 at 9:27:13 AM EDT -------~~ (b)(6),> To: "Conrad, Patricia (NIH/NIAIO} [E]" CbH6J>, NIAID FOG Cc: NIAID COGCORE, NIAID Media Inquir ies Subject: Media query: CNN, re: ASF's NAS web briefing on Saturday ----------- Elizabeth Cohen CNN Elizabeth.Cohen@turner.com Topic: Statement by ASF during Saturday NAS web briefing Deadline: urgent Hi Patty, Elizabeth would like to clarify something that Dr. Fauci apparently said about remdesiv ir during his NAS web briefing on Saturday. The transcribed segment of the talk that she is focused on says: "Remdesivir is the one that's gotten the most publicity. It is interesting that if you look at it in a prophylactic therapeutic model in MERScoronavirus infection, it looked pretty good. There was clinical benefits just reported a couple of weeks ago of SARScoronavirus 2 in rhesus macaques." She wants to clarify what Dr. Fauci meant by looking at remdesivir " in a prophylactic therapeutic model in MERS"-whether this means in an animal model or something else. It sounds like that phrase is referring to the RML study in which remdesivir successfully prevented disease in MERS-infected rhesus macaques, as reported in the Feb. 13 NIAID media availability pasted below . Is that correct? Best, Laura Remdesivir Prevents MERS Coronavirus Disease in Monkeys Results Support Testing Antiviral Against 2019 Novel Coronavirus February 13, 2020 The exper imen tal antiviral remdesivir successfully prevented disease in rhesus macaques infected with Middle East respiratory syndrome coronavirus (MERS-CoV),according to a new study from National Institutes of Health scientists. Remdesivir prevented disease when administered before infection and improved the condition of macaques when given after the animals already were infected. The new report from NI H's National Institute of Allergy and Infectious Diseases (NIAID) appears in the Proceedings of the National Academy of Sciences. MERS-CoVis closely related to the 2019 novel coronavirus (SARS-CoV-2,previously known as 2019-nCoV) that has grown to be a global public health emergency since cases were first detected in Wuhan, China, in December. Remdesivir has previously protected animals against a variety of viruses in lab experiments . The drug has been shown experimentally to effectively treat monkeys infected with Ebola and Nipah viruses. Remdesivir also has been invest igated as a treatment for Ebola virus disease in people. The current study was conducted at NIAID's Rocky Mountain Laboratories in Hamilton, Montana. The work involved three groups of animals: those treated with remdesivir 24 hours before infection with MERS-CoV; those treated 12 hours after infection (close to the peak time for MERS-CoVreplication in these animals); and untreated control animals. The scientists observed the animals for six days. All control animals showed signs of respiratory disease. Animals treated before infection fared well: no signs of respiratory disease, significantly lower levels of virus replication in the lungs compared to control animals, and no lung damage. Animals treated after infection fared significantly better than the control animals: disease was less severe than in control animals, their lungs had lower levels of virus than the control animals, and the damage to the lungs was less severe . The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoVand COVID-19, the disease that SARS-CoV-2 causes. Several clinical trials of remdesivir for COVID-19 are under way in China, and ot her patients with COVID-19 have received the drug unde r a compassionate use protocol. The Biomedical Advanced Research and Development Aut hority (BARDA), part of the U.S. Department of Health and Human Services, also provided support for this study . Gilead Sciences, Inc., developed remdesivir, also known as GS-5734, and collaborated in the research . MERS-CoVemerged in Saudi Arabia in 2012 . Through December 2019, the World Health Organization had confirmed 2,499 MERS-CoVcases and 861 deaths (or about 1 in 3). Because about one-third of MERS-CoVcases spread from infected people being t reated in healthcare settings, the scientists suggest that remdesivir could effectively prevent disease in other patients , contacts of patients , and healthca re workers . They also note the drug might help patients who are diagnosed with MERSor COVID-19 if given soon after symptoms start. ARTICLE: Ede Wit et al. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. PNAS DOI: 10.1073/pnas .1922083117 . WHO : NIAID Director Anthony S. Fauci, M .D., and Emmie de Wit, Ph.D., a principal investigator in NIAi D's Laboratory of Virology, are available to comment on this study. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 27 Apr 2020 14:11:59 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Antigen Mi croarray Please t ake a look and handle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------- --=~ From: Anderson, Cassandra (NIH/NI DDK) [E] Date: Monday, Apri l 27, 2020 8:17 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Coronavi rus Antigen Microarray -------- (b) (6)•> (b)(6)> Good morning Dr. Fauci, I work in NIDDK in bldg. 50 in the Laboratory Endocrinology and Receptor Biology. Thank you for all the information yo u have provided to our nation . I also want to say you are doing a terr ifi c job in handl ing the COVID-19 v irus, without you and your staff I don't know wher e our country would be. I received the ema il below this morning from Jiang Yufei from Sino Biological. Not sure why I was sent this email, but I tho ught of you and your staff . Please see the email below . Thank you again for all that you are doing to help keep us safe ! Stay safe! Cassandra Anderson Admin istrative Professional Bldg. SO Room 4133 301-402-7845 From: Yufei Jiang Date: Monday, April 27, 2020 8:04 AM To: Anderson, Cassandra (NIH/NIDDK) [E) Subjec t : Coronavirus Antigen Microarray ------------- (b)( > Hi Cassandra, Happy Day! I am excited to let you know that Sino Biological jus t released Coronavirus antigen Microarray (CoVAM) which belongs to our Sinommune™ Mu ltiplex Antigen Microarray product line. You may get more details from the following link: https ://www. sinobio logica I.com/ research/virus/ coronavi rus-array Currently the standard pre-printed CoVAM array is sold in the unit of slide, 16 arrays/slide. In each array there are 65 antigens related to the viruses that can cause upper respiratory tract infections including the most recent SARS-CoV-2.The list price is $3,200/slide . Please contact me for how to place the order if you are interested or need more information. So far, this array has mainly been used for two purposes: 1) Sero-surveillance studies of COVID-19 infect ion, and 2) Evaluating antibody reactiv ity in animals (monkeys and mice) after vaccination . Please be advised that our array is for research use only (RUO), not for the diagnostic purpose which needs the FDA approval. After you run the samples on the slide, you may read the slide on the following compatible machines: https://www.innopsys .com/en /lifesciences-products/m icroarrays/innoscan https://www.moleculardev scanners#gref ices.com/produc ts/additional -products/genepix-microarray-systems- https://www.agilent .com/en /produ ct/cgh -cgh-snp-microarray-platform/cgh- cgh-snp-microarrayscanners-equipment/surescan-m icroarray-scanne r-228493 Thanks. -Yufei Yufe i Jiang, PhD Manager, NY, MD, DC, VA Sales & Business Development Sino Biological US Inc. 1400 Liberty Ridge Dr., Suite 101 Wayne, PA 19087 Celli (b) (6) Email: yufei jia ng@sinobiological.com www.sinobiological.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 14:11:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Otto e Mezzo - Ita lian Show Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representative s. From: Torchia Patrizia Date: Monday, Apri l 27, 2020 8:05 AM To: Fauci, Anthony (NIH/NIAID) [E] --------, .....,....,= --------- (b)(6) Subject: Otto e Mezzo - Italian Show Dear Mr. Fauci, I'm Patrizia Torchia, I'm a journalist and I am a member of the team on the It alian show Otto e Mezzo, hosted daily by journa list Lilli Gruber on La7 channel. I'm reaching out to invite you in our show. Mrs. Gruber would be honored to have you, Dr. Fauci explore in more depth the challenges Coronavirus has forced th e world to face. Can make this happen? Below is Lilli Grube r's bio and a brief descript ion of the show. WHO : Lilli Gruber is the editor-in-chief and host of Italy's most influential political daily talk show, "Otto e mezzo", airing on prime-t ime on La7 TV. She's received Italy's most prestigio us journalism awards for her work and was the first woman to ever conduct the prime -time News broadc ast in Italy (RAI TV, 1987). As a foreign correspondent she covered most of last 30 years' maj or world events, from the fall of t he Berlin wall to 9/11 to the Iraq war. Beside her te lev ision work, Ms. Gruber wrot e eleven bestseller books includ ing "Eredita", which was top seller for 20 weeks and ran 14 reprints. In 2004, Ms. Gruber won a head-to-head campaign against Silvio Berlusconi by a large margin of votes and was elected to the European Parliament. There, among other appointments, she was the Head of the EU Delegation to the Gulf States and Yemen and a member of the EU Delegation to Iran. "Otto e m ezzo" Italy's most influential political daily ta lk show shown on prime-time on La7 TV. Through interviews with elected political figures and candidates for office, commentators, and journal ists, the show focuses on international political news and economy wi th a special focus on Italy and Europe. Beginning in 2008 "Otto e Mezzo" became Lilli Gruber's way to keep her commitment to holding those in power accountable by asking questions and touching on topics citizens are curious about. Otto e Mezzo airs Monday to Saturday from 8:35pm to 9:10pm. Within this time-frame Paolo Pagliaro's news column "II Punto" stands out for accuracy and thoughtfulness by pulling the thread on the highest rated issues in an agenda. During the current season Otto e Mezzo has become Italy's most watched political talk show reaching an average of 7.3% of share wi t h 2.5 million viewers per day. Production location( s): La7 studios, via Umberto Navaro 32, Rome, Italy Presen t ed by : Lilli Gruber Origina l net w or k: La7 Executiv e produ cers: Stefania Bucciarelli Directed by: Lorenzo Font ana www.live.la7.it www.ottoemezzo.la 7 .it Twitt er: @OttoemezzoTW) Face book : Ottoemezzola7) Thank you in advance for t he considering. Looking forward to hearing from you. Patty Torchia Otto e Mezzo (b)(6) Fauci, Anthony (NIH/N IA ID) [E) Mo n, 27 Apr 2020 14:08:24 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Fauci and PayPal From: Date: To: Subject: Not really. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad , Patricia (NIH/NIAID) [E] Date: Monday, Apri l 27, 2020 9:54 AM To: NIAID OD AM (b)(6) Subject: FW: Fauci and PayPal Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liab ility for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. ___________ ... From: Fetalvo , Ninio J. EOP/OVP (b)(6) Date: Monday, April 27, 2020 9:51 AM To: Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: Fauci and PayPal ----------------- == (b)(6) FYI-Defer to you on this. From: Miller , Amanda Date: Monday, April 27, 2020 9:18 AM To: Fetalvo , Ninio J. EOP/OVP__________ (b ""'~"'(= 6) Cc: Walters, Lindsay Subject: [EXTERNAL] Re: Fauci and PayPal Hi Ninio, We are wondering if Dr. Fauci would like to have a taped Skype conversation with PayPal CEOand President Dan Schulman to talk about safety measures, health and science tied to COVID-19. We wou ld air the conversation during a global employee all hands to o ur 23,000 employees and then we could syndicate parts of it externally on our social channels. Thanks for any help in reaching Fauci's team . Thanks, Amanda Amanda Christine Mill er Senior Director, Corporate Communications 408.219.0563 @PayPalNews • PayPal Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 14:07:40 +0000 Lerner, Andrea {NIH/NIAID) [E] RE: From: Date: To: Subjec t : (b) (4) ------------------------ Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: {301 496-4409 E-mail: (b)( The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intend ed recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Lerner, Andrea {NIH/NIAID) [E) Date: Monday, April 27, 2020 10:05 AM To: Fauci, Anthony {NIH/NIAID) [E) -----Subjec t: Re: (b)( --------- > -= (b-s-r )( =6) ------------------------ (b)(4 I will make sure they get a response! Fr om : "Fauci, Anthony (NIH/NIAID) (E]" Date: Sunday, April 26, 2020 at 8:43 PM To: "Lerner, Andr ea (NIH/NIAID) [E]" Subject: FW: Upd ate: --------- (b)(6) > ----------=-:-:-= Cb)(6) (b)(4 -------------------------- Please respond to this person. Thanks. From: Kircheis Dr. Ralf Se nt: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Ste phanie {NIH/NIAID) [E)_________ --------~~ Cb _H_6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Cc: '-:-""'."""".~-:----::== Subje ct: Update: 1mportan ce: High (b=) =(6) :::::..: ; K :.:.: i.:..: rc:.:. h~e.:.: is..:D:.;. r.:.. . :.:. Ra :.;l.:.. f< ..:R =K =i= rc=h=e= is:= @:::s:::: y:::: nt=a=co :::: 1 :1. :::::: d:::. e>____ ------------------------ Dear Dr. Fauci, dear Dr. Coomes, ,.._,,._, (b)( 4) thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19research team. Has the project already been initially evaluate d by the team? Are there any quest ions or need for additional information? (b) (4) Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen Gru~en / Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syntacoll.de Phone : +49 9441 686048 s~ntacoll Syntacoll GmbH, Donaustrasse 24, 0·93342 Saal a. cl. Dcnau Tel: +499441 / 68 60 0, Fax: +49 9441/6860 30 Handelsreg ister : Amtsgericht Regensburg - HRS 1612 USt- JdNr. DE 128580796 Gesch3ftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Jhnen zustehenden Rechten, finden Sie unter wwwsvotacon. deJdatenschutz Von: Coomes, Stephanie (NIH/NIAID) [El Ge send et : Montag, 13 . Apri l 2020 02:37 An: Kircheis Dr. Ralf Betr eff: RE: ____________________ -------------- (b)(6) Cb _H_4)_,_ C_ H b _5) Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the National Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID's Office of Scientific Coordination and Program Operations, I am pleased to respond . I want to thank you for reaching out to share this informat ion and let you know that your mes:;age ha:; been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordinat ion and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infect ious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville, MD 20892 (b)(6) (b)(6) Disclaime r: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inally intended recipient. If you have received th is emai l in erro r, please inform t he sender and delete it from your mailbox or any ot her storage devices. The Nationa l Institu te of Allergy and Infectious Diseases shal l not accept liability for any statements made that are the sender 's own and not express ly made on behalf of NIAID by one of its represe ntatives . From: Kircheis Dr. Ralf ') Date: Wednesday, Apr il 8, 2020 2:49 AM To: Fauci, Anthony (NIH/NIAID) [El ..------ (b)( ~ > --,.(b.._)= c >; Billet, Courtney (NIH/NIAID) [El (b)(6)>; NIAID Ocpostoffice (NIH/NIAID) Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)(6>i>; Foster, Erin (NIH/NIAID) [El (b)(6) Foster, Sarah {NIH/NIAID) [El CbH >; Vasilenko, Olga {NIH/NIAID) [El (b)( >; Vasquez, Aurelio (NIH/NIAID) [El CbH >; Vostal, Alexander (NIH/VRC) [Fl (b)(6J>;VazquezMaldonado , Nancy (NIH/NIAID) [El (b)( >; Austin, James (NIH/NIAID) [El CbH '>; Agulto, Liane (NIH/NIAID) [E] CbH6J; Deckhut, Alison (NIH/NIA ID) [El (b)(6) Kircheis Dr. Ralf -------- ---------- Subject: WG: 1mportance: High ------------------------ (b) (4), (b) (5) (b) (4), (b) (5) Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some pote nt ially impo rtant exper imenta l data and a new proposa l for treatment of COVID-19 patients with acute respiratory distress syndrome and o rgan failure. Sorry fo r the broad distribution but I wanted to make sure tha t my message reaches you. (b) (4), (b) (5) (b) (4). (b) (5) Please forward this mail to the colleages you cons ider relevant for evaluation, discussion and consideration for your clinical strategy for COVID-19 . Please let me know if additional informations are necessary. To my person: I have MD PhD degree and have many years experience in phar maceutical development {Boehringer lngelheim ), Biotech {lgeneon , Aphton , Virolog ik GmbH) {for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll {part of lnnocoll). I am providing this information personally in order to help to find a treatment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis {MD PhD) (b)(6) rkircheis@svn ta coll .de (b) (4), (b) (5) (b) (4). (b) (5) Mit freundlichen Grur..en / Kind regards Dr. Ralf Kircheis Director R&D Research & Development Mail: RKircheis@syntacoll.de Phone: +49 9441 686048 s~ntacoll Syntacoll CmbH, Donoustrasse 24, D 93342 Saa l a. d. Dcnau Tel: +49 9441 / 68 60 O, Fax: +49 9441 / 68 60 30 Handelsregister: Amtsgericht Regensburg - HRB 1612 USt-ldNr DE 128580796 Gescha~sfuhrenn: Dr . Alexandra Dietr ich Unsere Hinweise zum Datenschutz, insbesondere zu den Ihnen zustehenden Rechten, finden Sie unter www .syntacoll .de/da tenschutz (bX5) -PCP. From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 27 Apr 2020 12:33:44 +0000 To: Jeremy Farrar Subject: RE:NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 part icipati on Thanks, Jeremy. I saw the report in the Post from Saturday. These children had mostly respiratory disease and diarrhea . I wi ll check with t he docs at DC Children's Hospital about the presence of " mult isystem inf lammatory state". This could just be the advanced stage of their disease compatible with advanced SARS-COV-2 Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . _________ .... From: Jeremy Farrar Date: Monday, Apri l 27, 2020 7:38 AM To: Fauci, Anthony (NIH/NIAID) [E] _____ GAO (b)(6)> (b)(6) --,a(b.~= ,... c6)>; Dzau, Victor J.; George (b)(6) ; Hannon, Emma ; Conrad, Patricia >; Teresa Miller de Vega (b)( >; (b)(6); Rebeka Yasmin - CEPI (b)(6); ben.tinker@cnn.com; Amanda.Sealy@cnn.com; Neel.Khairzada@turner .com; Tia.Miller@turner.com; (b) (6) McGinnis, J. Michael ; (b)(6) Mun, Jenny ; (b)( Redfield, Robert R. (CDC/OD) (b)( '> Subject: Re: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation ========-=-~(b)( ---- Thanks Tony- have asked for that and wi ll share as soon as I can. -----~= I believe the re have been reports in the Washington Post. https://www .washingtonpost .com/local/new-dc-hospital-numbers-suggest-kids-do -face-some-riskof-coronavi rus-hospitalization/2020/04/25/Se 78c268 -86fe-11ea-878a-86477 a724bdb story.html From: "Fauci, Anthony (NIH/NIAID) [E]" Victo r Dzau , Geo rge Gao (b)( (b)(6) Cc: Ric hard Hatchett Patricia (NIH/NIAID) [E]" ---------- " ann n, Emma" , "Conrad, Cb)<>, Teresa de Vega Cb>< , Rebeka Yasmin - CEPI "ben.tinker@cnn.com" , ------------- (b) (6) "Amanda. Sealy@cnn .com " , "Neel. Kha irzada@turne r.com " , "Tia.Miller@turner.com " , (b)(6) "McGinnis, J.Mic hael" , (b)(6)"Mun , Jenn y" , CbH6)"Redfield , Rob ert R. (CDC/OD)" (b)(6)r------------ Subject: RE: NAS Annual Meeting Session on COVID-19-- Information regarding your Saturday April 25 participation Jeremy: Thanks for the heads up. Is t here any more detailed description of the precise clinical manif estation s? They describe a "mul t isystem inflammatory state 11 • It is vasculitis or anything more specific? Could be an infectious agent that has nothing to do with SARS-CoV-2 infection even though some children are circumstantially infected with SARS-CoV-2orit could be a post-SARS-CoV-2 inflammatory syndrome , perhaps a Kawasaki syndrome-like disease. Please keep me informed if you hear any further information. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Jeremy Farrar ________ (b _)_(_ 6)> Date: Monday, April 27, 2020 7:13 AM ~= To: Fauci, Anthony (NIH/NIA ID) [E]------_______ (b _H_6); Dzau, Victor J.; George GAO (b)(6) > (b)(6) Cc: Richard Hatchett Hannon, Emma ; Conrad, Patricia "':""""-:---"".'"":"-:.:=======-~~ (NIH/NIAID)[E] (b)(6) Teresa Miller de Vega (b)(6) ; _,, (b)(6)· Rebeka Yasmin - CEPI (b)( >; ben.tinker@cnn.com; Amanda.Sealy@cnn.com: Neel.Khairzada@turner.com; Tia.Miller@turner.com; (b) (6); McGinnis, J.Michael< MMcGinnis@nas.edu>; (b)(6)> ; Mun, Jenny ; (b)(6) Subject: Re: NASAnnual Meeting Session on COVID -19 -- Information regarding your Saturday April 25 pa rticipat ion ____ --=====~--~--~--~:----:--~ To be aware of - news over night so a huge amount of uncertainty - important for COVID19now, and a potenti al concern for how we view immunity, protection, post-infect ious immunopathology. https://www .hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-beemerging-in-children/7027496.article https://t.co/Bj6YHU8zi From: "Fauci, Antho ny (NIH/NIAID) [E]" (b)(6) Date: Sunda y, 26 April 2020 at 19:52 To: VictorD zau , George Gao ______ ...--------~ Cc: Jerem y Farrar (b)( 6} , Rich ard Hat chett _________ = (b _> _<6) _ "Hanno n, E mma" , "Conrad , Patricia (NIH /NIA ID) [E]" (b) (6)>, Teresa de Vega (b) (6)>, Rebeka Yasm in - CEPI (b)( , "ben. tinker@cnn.com " , "Amanda.Sealy@cnn.com " , "Neel.Khairzada@turner.com " , "T ia.Mi ller@t urner.com " , (b)( 6) "McGinni s, J.Mi chael" , ---------------- CbH6) >, "Mun, Jenny" , (b)( 6) Subject: RE : NA S Annual Meeting Sess ion on COVID-19 -- Information regardin g your Saturda y April 25 participation It was a real pleasure to join all of you on this important session. Many thanks for inviting me. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX : (301) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dzau, Victor J.< VDzau@nas.edu> Date: Saturday, Apr il 25, 2020 3:59 PM To: George GAO (b)(6) Cc: Fauci, Anthony (NIH/NIA ID) [E] ----------------~~ ; Hannon , Emm a ; Conrad, Patricia (NIH/NIA ID) [El ------------------------- (b) (6) ben.tinker@cnn .com; Amanda.Se aIy@ cn n.com ; Neel.Khairzada@turner.com ; Tia.Miller@turner.com ; (b)(6) McGinnis, J.Michael< MMcGinnis@nas.edu >; (b)(6J>; Mun, Jenny (b)(6); haja.bally@cepi.net Subject: Re: NASAnnual Meet ing Session on COVID-19 -- Informat ion regarding your Saturday April 25 ------ participation Dear Jeremy, Tony, Sanjay, George, Susan and Richard, Than k you so much for your sup erb contributions. It wa s a spectacular sessi on- a tmly inspirin g one . I am grateful to all of you . Hop e to see you soon . Warm est regards, Victor On Apr 25, 2020 , at 1:22 PM, George GAO ------- CbH6) > wrote: I am waiting for being connected and w ill use slides which were sent to your office George ~§ ilt1¥-JiPhone 1±2020~4 Fl24 B . ~Ji: 0 l :49, Dzau , Victor J. Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really looking forward to this panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00-3:30 pm ET. There is tremendous excitement and enthusiasm, and registrat ion is through the roof. I am sending this note to do a last minute check to see if there is anything you need from me . I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I would greatly appreciate it if you wou ld respond to this email. Best, Victor PS, (b)(6) my special assistant, will be sending you additional information about the session logistics short ly. From: Dzau, Victor J.< VDzau@nas.edu> Date: Thursday, Apr il 9, 2020 11:01 AM (b)(6); 'ben .tinker@cnn.com ' ; ---------'Amanda.Sealy@cnn.com ' ; 'Neel. Khairzada@turner .com' ; 'Tia.Miller@turner .com' ; 'hujr@chinacdc.cn' (b)(6) Subject: RE: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 par t icipa t ion Dear all, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are , I am sending this email in lieu of a call to prepare for the session. As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVlD-19 response. I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic , treatment and vaccine development , and the importance of commun ication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandem ic. Then , I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration . I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the VvHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China 's response to the pandemic and lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristics of SARS COV2, insights into its pathobiology, immunity and development ofa pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wtll comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Following remarks from each panelist, we will have a moderated discussion amongst ounelves - I will ask you a set of questions ( 15 mins) and then we will take questions from the web (25 mins). To prepare me to be your moderator , please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun, Jenny sent: Wednesday, April 8, 2020 10:56 AM To: (b)(6) 'ben .tinker@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Nee l.Khairzada@turner.com'; 'Tia.Miller@turner .com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Dear Speakers: I am the logist ical contact for the COVID-19 session that will be held as part of the Ann ual Meet ing (online) program on Saturday, Apri l 25 at 2:00 pm EDT Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session wi ll be live webcast and the general publ ic will also be able to watch t he session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting. We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday , April 25 at 1:30 pm EDT) to allow the technical staff to check connect ions and prepare for the session. Detai ls on how to connect will be sent before t he meeting . We w ill list you in our promotional materials as noted below . If this is incorrect , please let me know . Anthony S. Fauci, Directo r, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microbiology , Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient with Zoom and other on line meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a training session this week or next week. If you wou ld like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions , please let me know. Regards, Jenny ********************~*********** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:45:27 +0000 (b)(6) Subject: SNL revi ew OKAY, so here is something even better than having Brad Pitt portray me on SNL. It is a recent review of Pitt ' s performance in which the TV reviewer said : " Kicking things off, the Oscar winner dropped jaws during the cold open with his monologue about President Donald Trump's recent (and concerning) comments about COVID-19. "Good evening, I'm Dr. Anthony Fauci," Pitt began his monologue and looked nearly identical to the director of the Nationa l Institute of Allergy and Infectious Diseases." Someone said Pitt looked "nearly identical" to me. Yikes!! Q Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Be thesda, MD 20892-2520 Phone: Cb)(6) FAX : (301 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 18:37:57 +0000 Barnes, Freddie RE:Appr eciation Freddie: Many thanks fo r your kind note . It is much appreciated . Best regar ds, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barnes, Freddie Date: Sunday, April 26, 2020 10:48 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Appreciation ------~~ Dr. Fauci I just wanted to express my profo und appreciat ion to you for your work during this COVID-19 pandemic. I especially appreciate how you have spent considerable time and capital reaching out to the Black and brown communities. I saw exerts of your snapchat w ith W ill Smith and saw nearly all of your interview on the Breakfast Club. I regret I have to send an email to you re this matter. But t his is the day we live in. Minority communities continue to be over-looked in crises and the impact of such crises on their respective communities. For you to be int entional about keeping the minor ity communities in th e loop is commendable, especially since these communities will be absorbing the disproport ionate share of the sicknesses and deaths coming from COVID-19. Thanks for all of what your are doing in keeping the nation informed. Thanks for informing based on the facts, data, and truth. Take care and "Cover your six." Email correspondence to and from this address may be subject to the North Carolina Public Records Law and may be disclosed to third parties by an authorized state official. From: Date: To: (HHS/OASH) Fauci, Anthony (NIH/NIAID) [E) Sun, 3 May 2020 13:29:53 +0000 Adams, Jerome (HHS/OASH) --------~~ ---------- CbH6) 1Giroir, Brett (b)(6) Cc: Subject: RE: High touch points (b) (5) From: Adams, Jerome (HHS/OASH) --------~= Date: Sunday, May 3, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) (E]------ (b) ( "> (b)(6J>; (HHS/OASH) (b)(6)> Cc: CbH6J Subject: Fwd : High touch points ---------- (b)( ; Giroir, Brett Please see short thread below. Senator Young reached out to me about this and I forwarded to CDC. As (b)(5 Jerome VADM Jerome Adams 20th US Surgeon General Begin forwarded message: From: "Adams, Jerome (HHS/OASH)" 0 at e: May 3, 2020 at 7:32:46 AM EDT To: "Jernigan, Daniel B. (CDC/DDID/NCIRD/1 D)" .;._.:...::~~--Cc: "Schuchat, Anne MD (CDC/OD)" (b)(6) --------- __ (b)( > (b)(6)> Subj ect : Re: High touch po ints Thank ou. (b) (5) (b) (5) Please keep me posted . And should I refer the senator to you or someone at CDCto close the loop? Thanks! J VADM Jerome Adams 20th US Surgeon General On May 2, 2020, at 7:08 PM, Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) (b)(6)> wrote : ------ ADM Adams: Thank s for sending this. There has been a lot of guidance on disinfection and cleaning, notably some very recent collaborative work we have done with EPA(https://www .cdc.gov/coronavirus/2019-n cov/communi ty/ reo penguidance.html) . Attached are two documents focused on re-opening America with emphasis on cleaning and disinfection, including high-to uch surfaces. Also below are a number of websites that address cleaning and disinfection which point out the importance of disinfecting high-touch locations like doorknobs. They give guidance how to clean them, but they don't address methods fo r using a paper towel or Kleenex to first turn the knob and then discard the towel. (b)(5) Thanks Dan. Daniel B. Jernigan, MD MPH Director, Influenza Division; HHS CDC Lead, FEMA-HHS COVID-19 Response Captain, USPHS(RET) National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention 1600 Clifton Rd NE, Atlan ta, GA 30329 Phone (b) (6) , Cell (b) (6) (b) (6) www.cdc.gov/flu ------- https://www.cdc.gov/coronavirus/2019-ncov/community/disinfectingbu ildi ng-facil ity. html https://www.cdc.gov/coronavirus/2019-ncov/prevent-gettingsick/disinfecting-your-home.html https://www.cdc.gov/ coronavirus /2019-ncov / community/disinfectingbu i ldi ng-facil it y-H.pdf Date: Friday, May 1, 2020 5:35 PM --------Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) .:.._~~~--Schuchat, Anne MD {CDC/OD) > (b) (6)> From: Adams, Jerome (HHS/OASH) To: Cc: Subject: High touch points __ (b)( Dr. Jernigan, I got a message from a Senat or asking why we didn't have specific reopening recommendations for "high touch" points like door knobs/ handles/ elevator buttons . The Senator sta ted that (b) (5) Jerome VADM Jerome Adams, M D, MPH 20 th U.S. Surgeon General From: Date: Fauci, Anthony (NIH/N IA ID) [E) Thu, 30 Apr 2020 22:37 :05 +0000 Hahn, Stephe n;Debi Birx;Redfie ld, Robert R. (CDC/OD);Verma , Seema (CMS/OA) RE:Serology Studies in Germany To: Subject: Than ks, St eve ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)( •> Date: Thursday, April 30, 2020 6:34 PM To: Debi Birx (b)(6l>; Redfi eld, Robert R. (CDC/OD) Seem a (CMS/OA ) (b)( >; Fauci, Anthony (NIH/NIAID) [E) --------- (b)( , (b)(6) Subject: Fwd : Serology Studies in Germany Interesting information from Germany --------- (b) (6)> From: Shuren, Jeff Date: Apr il 30, 2020 at 5:46 :27 PM EDT To: Hahn , Stephen (b)(6J>, Shah, Anand (b)( >, Guram, Jeet Lenihan , Keagan ___ ....:,__:...,__..!:::=~~~---........!=====~~-->, Rom, Colin ======== (b)(6J>, (b)( (b~)(~6)~>-- Subject: Serology Studies in Germany FYSAregarding serology studies being conducted in Germany, including status of tests to be used for t hose studies. This is the follow up to what I sent you last week . (b)( 5 From: Hoshi, Ryan (b)(6) Date: Thursday, April 30, 2020 3:17 PM To: Shuren, Jeff (b)(6) Cc: Nalubola, Ritu O'Leary, Brendan (b)(6); louati, Claudia (FSN)* .:=:::::========~~ .;.....!:::========~;;-" (b) < >; Torres, Melissa A StenzeI, Timothy (b) ( > Subject: FW: PLEASEREVIEW» Meeting Notes - Call with ----------- (b)(5 (b)(5) (b)(S ) (b) (5) Thank you, Ryan _____ Ryan A. Hoshi , Ph.D. Int ernat ional Po licy Analyst .,_ (b) (6)1 mobil e I Center for Devices and Radiological Cb)(6) Health I_______ Cb .., .).,.., (6) .., I phon e U.S. FOOD& DRUG ADM IHISTUTION Excellent customer service ,s ,mporta~t to us Please take a moment to provl:fe feedback regarding the customer service you have received click here for survey From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 27 Apr 2020 14:14:36 +0000 To: Halkovich, Townshe nd Connie Subject: RE:Appr eciation to my hero --Dr. Fauci--our country 's voice of reason in th ese unsett ling, uncertai n t imes--We NEED YOU!!!! Please don' t leave us now wh en w e need you most!!! Conn ie: Many t hanks fo r you r kind note . Mu ch appreciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Halkovi ch, Towns hend Connie Date: Monday , April 27, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b)(6) (b ""'~""'(6) = > Cc: Halkovich , Tow nshend Connie (FDA/OC) (b)(6) Subject: RE:Appreciat ion to my hero -- Dr. Fauci--our country 's voice of reason in these unsett ling, uncertain t imes--We NEEDYOU!!!! Please don 't leave us now w hen we need you most!!! Wher e is Dr. Fauci? I know where Dr. Fauci is-I saw him on SNL- remarkably he looked like Brad Pitt - except [to many of us] Dr. Fauci is better looking . Smile, wink Why? We look with our hearts I remember someone asked Dr. Fauci [in jest ] who would he like to represent him in a movie ...Dr. F. said Brad Pitt . Well - Dr. F. Your dream suggesti on came t rue. But, in ma ny of ou r hear ts- NO ONE can take t he place of our beloved , we ll respected, honored Dr. Anthony Fauci !!! ! God Bless Amer ica, God Bless Dr. Fauci !! ! From: Halkovich , Townshend Connie Se nt : Friday, Ma rch 13, 2020 11:06 AM (b) (6)> To: 'anthony .fauci@nih.gov ' (b)(6) Cc: Halkovich , Townshend Connie Subject: Appreciation Dear Dr. Fauci: 1st & foremost - please keep you rself healthy ....get more rest than 3 hrs/nigh t.© Why? We need you! THANK YOU for all you r very informat ive updates . YOU are voice of reason...in t ime of coronavirus fear ...you give us hope ...saying that action is what is needed ... not fear! You are someone w e can be proud of ...you provide service we can coun t on!!!! God bless You & Your Family!! ! Warmest Regards from: Connie Leigh Townshend Halkovich, Management Analyst, 410-867 -0878, #FDA OIMT D10 Proud: Peo le & Service ou can count on!© (b)(6) My Wish 4 U: Peace, Love. Laugher -blessed Z work with U ALL! Abe Lincoln: "folks are as happy as they choose 2be" -B happy all circumstances -H ope all well with you, yours--ifnot, pretend it is. FDA M ission: Responsible for protecting public hea lth by ensuring safety, efficacy/sec urity of human & vet. drugs, biol. products, med. devices, aur nation 's food supply, cosmetics, & products that emit radiation. D10 Mission: -Provide excellent implementation, aperatian , maintenance of IT {equipment, services} to promote FDA's Public Health Mission. D/0 Vision: Provide state -of-the -art IT services-inclusive of surrounding policy, planning, customer service, in tegration, & oversight necessary to make the mission successful & sustainable. From: Fauci, Anthony {NIH/N IAID) [E) Date: To: Tue, 5 May 2020 22:26:27 +0000 Foikers, Greg (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Stover, Kathy (NIH/N IAID) [E);Routh , Jennifer (NIH/N IAID) [E];Awwad , David (NIH/NIAID) [C] Cc: NIAID OD AM Subject: RE:ASF RE: Dr . Fauci video reque st: Public Service Recognit ion Week Attachment s: ASF pub lic service recognition - w ith tracked edits -05-0 5-2020 .docx 0 See minor tr acked changes. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (N IH/ NIAID) [E] Date: Tuesday, May 5, 2020 6 :16 PM CbH > Cb ~H=6)>; Stover, Kathy (N IH/NIA ID) [E] To: Billet, Courtney (NI H/NIAID) [E] -----~ CbH6J> ; Routh, Jennifer {NIH/ NIAID) [E] David (NIH/NIA ID) [C] CbH 6>1;Awwad, CbH6J> Cc: NIA ID OD AM Subject: ASF RE: Dr . Fauci v ideo request: Pub lic Service Recognition Wee k ASFHere is a sho rt script for Public Serv ice Recognition Week . We agreed to do a short video ASF - can u tweak as needed? David, could u record in some format that is easy? Cell phone or other I just learned they want by COB tomorrow << File : ASF public service recogn ition.docx >> From: Seigfreid , Kim (NIH/OD) [E] CbH6J> Date: Monday, Apri l 27 , 2020 4:30 PM To: Billet, Courtney (NIH/NIAID) [E] --------=-~ --------Cc: (b)(6J>; Stover, Kathy (NIH/NIA ID) [E] Routh, Jennifer (NIH/ NIAID) [E] (b)(6)> Fine, Amanda (NIH/OD) [E] Cb)( >; Polimeni, Lydia (NIH/OD) [E] (b)(6) (b)(6)>; Subject: Dr . Fauci video requ est : Public Service Recognition Week Hi there, Please see below. HHS is taking over the Partnership for Public Service IG accoun t next week for Public Service Recogn ition Week . They asked if Dr . Fauci would be willing to do a short 30-second or less prerecorded video thanki ng public servants for their work . It would be featured during the takeover , and also on NIH's other sm handles next week . It can be taken on a cell phone as sm does not require higher resolution . Let me know if you would like to accept or decline the request. Many thanks , Kim Kim Seigfreid Social Media Lead NIH Office of Communications and Public Liaison ph: (b)(6) (b)(6) From: Muhammad, Janell (HHS/ ASPA) (b)(6), Date: M onday, Apri l 27, 2020 4:10 PM To: Seigfre id, Kim (NIH/OD) [E] CbH6J> ; Channer, Am ber (OS/OASH) CbH6J>;Foster, Timothy (OS/ ASPA) CbH6)> ---------~~ ---------Cc: Palczewski, And rew (HHS/ASPA) --------- (b)(6J>; Sherman, Jennifer (HHS/OASH) Wi lker, Michael (HHS/ASPA) (b)( 6) (b)(6); CbH6J>;Pratt, Michael (OS/ASPA) (b)(6) Dine, Brooke (HHS/ASPA) Subject: Public Service Recognition Week Hello All, Hope eve ryone is ho lding up well ! OHR is taking ov er the Partnersh ip for Public Service (PPS) lnstag ram account during Public Service Recognit ion Week (May 3-9, 2020). The OHR team has reached out about want ing to develop a senio r leade r " mashup " video -perhaps including the DepSec. T They asked about the feasibility of this request. They also inquired about perhaps Dr. Fauci and the SG doing a pre-recorded video thank ing public servants for their work. I wanted to gathe r the troops so we can identify what all is being planned for this week of recognition and provide a POCfor OHRif the request is feasible . Happy to set up a call, if tha t is needed to discuss further . Thanks, Janell Janell Muhammad ASPA Digital Engagement (Team Lead) U.S. Department of Health and Human Services Email: (b) (6) Office: (b) (6) iPhone: Cb) (6) HHS on Facebook I HHS on Twitter I HHSLatino From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 5 May 2020 21:58:55 +0000 Adams, Jerome (HHS/OASH) RE:Update on Sara Alert What do you mean by ------------------------ (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Adams, Jerome (HHS/OASH) Date: Tuesday, May 5, 2020 2:49 PM To: Birx, Deborah L. EOP/NSC -------- (b)( > ""' Cb .H"""' .,...6J ; Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: FW: Update on Sara Alert Importance: High (b) (5) Jerome VADM Jerome Adams, M D, MPH 20th U.S. Surgeon General From: Jarris, Paul (b)(6J> Date: Friday, May 1, 2020 7:29 PM To: Adams, Jerome (HHS/OASH) CbH6)> ...;..::=======-~:a;Cc: W right, Janet (HHS/OASH) CbH6) -------~~ ---------- Subject: Update on Sara Alert Importance: High Dear Jerome, I hope you are well. Thank you for all you are doing to represent public health and our nation. It is very comforting knowing you are informing the nations COVID-19 response. I wanted to give you an update on called Sara Alert, the software program I am leading at MITRE. Sara Alert is being provided free of any costs and deployed in state, tribal, and local health departments to support public health in contact tracing and active monitoring of individuals in isolation and quarantine. We are engaged with ASTHO, NACCHO,CSTE,and the application is hosted live on APHL's AIMS platform. Sara Alert officially launched on April 3 and is currently supporting multiple jurisdictions including Commonwealth of the Northern Mariana Islands, Danbury, CT, and the State of Arkansas. It is also being rolled out in Washington, Arizona, Pennsylvania, Virginia, Maine and Vermont. We are getting ready to launch in additional jurisdictions over the next couple of weeks. We have recently responded to questions we were told came from the White House so I wanted to make sure you have background materials. I imagine you are the person that the President and Vice President would turn to for information. I am happy to arrange any briefing mater ials or demo that would be helpful for you to respond. As I mentioned previously, Sara Alert is a standards -based, open source tool that automates the process of mon itoring individuals exposed to or infected w ith COVID-19 (or any disease, it's configurable) - and wi ll serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations. Best wishes to you. Stay healthy for all of us. Paul ABOUT SARA ALERT In response to the COVID- 19 pandemic, the MITRECorporat ion, a not-for-profit that works in the publ ic interest, developed Sara Alert, a standards-based, open source tool in partnership with national public health organizations. Sara Alert automates the process of monitoring individuals exposed to or infected with COVID-19 (or any disease, it's configurable) - and will serve as an enduring national resource to contain disease. Sara Alert is free for use by public health organizations . • Sara Alert allows public health officials to import and enroll individuals (or households) at risk of developing or infected with COVID-19. • Individuals enter their symptoms daily via web, text, email or phone, allowing public health officials to focus on high risk and non-reporting individuals . • The web-based tool enables increased efficiency in tracking cases, leading to earlier containment of the virus and reduction of burden on public health resources. • Sara Alert is a national system and allows transferal of monitorees across jurisdictions for tighte r contact tracing. Sara Alert launched on April 3 and is now supporting multiple jurisdictions . Sara Alert YouTube Video : https://youtu.be/lQxAuNsg-RA Paul E. Jarris, MD, MBA Chief Medical Advisor Health Transformation Center MITRECorporation (b) (bJj (b) (6)] Off ice ====;::~ (b)( 6)] Mobile ----- From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sun, 3 May 2020 17:45:26 +0000 Lane, Cliff (NIH/NIAID) [El;Collins, Francis (NIH/OD) [El Lowy, Douglas (NIH/NCI) [E);Mascola, John (NIH/VRC) [El RE:Gallo and OPV (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) ( > From: Lane, Cliff (NIH/NIAID) [El Se nt : Sunday, May 3, 2020 1:22 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Lowy, Douglas (NIH/NCI) [El (b)(6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6) >; Mascola, John {NIH/VRC) [El (b)(6)> -------- -----~~ -------Subject: Re: Gallo and OPV Francis, (b)( 5) Cliff On May 3, 2020, at 12:55 PM, Collins, Francis (NIH/OD) [El _______ Hi all, Cb _H_6) wrot e: I'm a bit at a loss to know how to respond to Bob Gallo. Francis From: Gallo, Robert ---------- (b)( > Date: Sunday , May 3, 2020 12:07 PM ------~~ To: Collins, Francis (NIH/OD) (E] ..._______ Cb _) _(6) Subject: RE: Your query to Dr. Kadlec Dear Francis, It was a pleasure to hear from you, and yes, it has been a long time since we met or even spoke. Moons ago I was set to write to you after reading your wonderful book, but I ended up instead speaking with others about it. I should add at this point that I did not quickly respond to your email of a few days ago because I simply missed it. It is true that I strongly suggest that OPV be quickly (already it is not quickly) brought forward for induction of a strong innate immune response to prevent or markedly reduce SARS-CoV-2infection and/or severity until the field obtains a proven safe and efficacious vaccine producing a long lasting, adaptive immunity . OPV is very safe (notably for OPV 1 and 3 as bOPV which we will use and completely safe in a vaccinated population), simple, cheap, rather obvious, yet unique among the massive number of vaccines many (maybe most) of which are the same or at least if not exactly the same aiming at the same mechanism (targeting the spike and searching for the putative correlate of neutralizing Abs.). OPV should work for a few months and possibly longer. Also it should be working multip le times so I think could cover more than a few months, giving us time for a proven vaccine of adaptive immunity, which might be very long lasting as is hoped. In the main the WHO comments are correct. Of course we sought and have letters of support from them as well as from many others . Though they are again supportive in their notes to you, there is one item that surprises me. They add that there was no clinical efficacy results as yet. They know or certainly should know that there is plenty of clinical data for this concept with BCG,OPV, and live Measles vaccine. Needless to say this is what turned me on during our regular Global Virus Network (GVN)conference calls. (Incidentally GVN is an organization I have thought of bring ing to your attention. I th ink you would find it impressive and useful) . I would be happy to share with you the clinical observations with OPV if you wish. I would like to take a small diversion, but I suspect you are aware of these things. My colleagues and I respect the WHO because of its representation and because we have colleagues/friends there as well. However, sometimes bureaucracy of a massive degree leads to inaction or even much worse-- political expediency. I won't bother you with details of these unless you ask, but I had such experiences with HTLV-1 which we discovered in 1980 as the 1st human retrovirus and which cause not only the highest incidence of cancer(% of infections) of any virus and other fatal diseases as well but mainly in less developed countries (plus Japan) and again with HIV in 1984. Behavior was not beneficial. Perhaps it will be of relevance in the future because a few at WHO took a position to remove OPV (Sabin) in favor of IPV (Salk) in their polio eradication scheme. It was a huge failure. As my FDA collaborator, Konstantin Chumakov, says "Blessed be Bill Gates" because he saved OPV and saved the day and in so doing has produced a still better OPV. There is indeed data also for BCGas well as live Measles though I know less of the latter. BCG is less available, requires injection, harder to make, not as safe, and we think unlikely to be as effective as OPV. Nonetheless, we favor its use too. The mechanisms will be similar. You asked whether monkey trials are planned. For several reasons definitely not -though we are planning some monkey experiments, but not large enough for "clinical" conclusions. The main reasons are: 1) cost; 2) that billions not thousands or millions have received OPV safely and in our collective view (and we know the studies pretty well) protection has been clinically shown; 3) In a pandemic we wished to move quickly (so far we must say that has not been achieved). A typical monkey vaccine study will take time, but 4) in this case it would be a huge amount of lost time as monkeys require great doses of polio for infection and monkeys have to be trained to drink their orange juice. It would be hard to imagine that such studies would even give us useful information. On a final digression Francis I have had 36 years of on/off experiences with glycosylated spike proteins-their analyses immunologically and especially regarding use in vaccines and developing neutralizing Abs. I believe it will be a mistake to put most eggs in that basket. The risks: shortened antibody half life; 2) protection NOT correlating with neutralizing Abs; 3) sometimes hazards from them. Admittedly, they might work, but I trust and hope that not everything is going in this bag. If you wish to discuss this again I will be available. Finally, I hd no idea you were into vaccines or SARS-2nor any part of CoVID-19 disease, but I am very happy to learn this. Thanks. Bob Gallo From: Collins, Francis (NIH/OD) [E] (b)( > Date: Thursday, April 30, 2020 5:00 PM To: Gallo, Robert Cb)(6J> Cc: Disbrow, Gary (OS/ASPR/BARDA) CbH6J>; Kadlec,Robert (OS/ASPR/I0) Cb)( >; Tabak, Lawrence (NIH/OD) [E) CbH6J>; Shuy, Bryan (OS/ASPR/I0) Cb)( >; Johnson, Robert (OS/ASPR/BARDA) Cb)( >; Mascola, John (NIH/VRC)[E) (b)(6b ; Lane,Cliff (NIH/NIAID) (E] (b)(6J> --------Subject: You r query to Dr. Kadlec CAUT ION; Tbis message 01iginnted from II oon UMB, UMSOM, FPI , or UMMS cmnil sys tem . Wheth er the sender is known or not known, hover over any links before c]jcking and use caution opening attachments. Dear Bob, It's been quite a while since we've chatted. Bob Kadlec asked me to respond to your query about the possible use of OPV to activate innate immunity and provide COVID-19 protection. Has t his been tested in a non-human primate model? I note the recommendation below that says a clinical trial is planned - can you tell me more about that? As you can imag ine, we are all flat out on the vaccine development pathway! Franc is The use of oral polio vaccine(OPV) to prevent SARS-CoV2(Polio Eradication Campaign) There is no ev idence that ora l poliovirus vaccine (OPV) protects people against infection with COVID-19 virus. A clinical trial address ing this question is planned in the USA, and WHO w ill evaluate the evidence when it is available. In the absence of evidence , WHO does not recommend OPV vaccination for the prevention of COVID-19. WHO continues to recommend OPV as part of essentia l immunization services to prevent poliomyeli tis and as part of global polio eradication efforts. There are experimental signals from various studies over the years that OPV has non-spec ific effects on the immune system. These effects have not been well charac t erized and the ir clinical relevance is unknown. Such non-specific effects may not be limited to OPV, as other live vaccines have also been associated with noneffects (such as BCGvaccine against tuberculosis). specific protective No n live vaccines in contrast do not seem to have the same effects. The exact mechanism of non-specific be elucidated protection induced by live vaccines needs to f urther. Clinical studies could begin immed iately because the vaccines in question involving off-label are licensed and have an excellent safety record. Clinical tria ls use of various drugs licensed for other indications are currently underway. The existing scientific rationale suggests that the same should be done for OPV and other live vaccines. A study is currently be ing discussed with various including the US FDA,the outcomes of which partners and vaccine manufacturers, will be carefully assessed to determine potential use in the context of the spread of SARS-CoV2 until the time when specific vaccines and antiviral therapies are ready. From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10:28 AM To: Gallo, Robert CbH6l;Collins, Francis (NIH/OD) IE] (b)(6); Tabak, Lawrence (NIH/OD) [E] (b)( >; Shuy, Bryan {OS/ASPR/10) (b)( > Subject: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me. I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to br ing industry academia and government to consider scientific base approaches That you have described. Dr Collins has organ ized a vaccine group and I assess could be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert wrote: ---------- (b)(6)> Dear Dr. Kaldec , I have not heard from you in over a week. You mentioned getting back to me in a day or two. l ime is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely stimulation of innate immunity safe vaccine with powerful lasting several weeks, which can be given a second or third time, and with a historical track record of preventing other infections from entirely different RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some months, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely. I don't understand delays or apparent lack of interest . Who can possibly be against this? If you hear of hypothetical prob lems we can show you that these are false . Just ask the questions, and we can give you the evidence. However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you w ill pardon the expression . Some have been against th is who defend their old and fai led position on polio eradication w ith their promotion of the use of the inactivated polio virus vaccine. Please note that in the US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a complication and BILLIONShave received it . No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2 spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere . There are countries outside the US wanting to move fast on th is. We are waiting for your reply . Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbio logy, UMB, School of Medicine , Baltimore, And Co-founder and International Science Advisor of the Global Virus Network (GVN) From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Thu, 30 Apr 2020 15:17:01 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E);Lane,Cliff (NIH/NIAID) [El Cc: Subje ct: Tabak, Lawrence (NIH/OD) [El RE: Respone Francis: Thanks for th e not e. I will let Cliff speak for himself , (b) (5 ' (b) (5) --------you wish. 5> but I w ill let him speak for him self . We can discuss further if Cb>< Best , Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------- (b)(6)> From: Collins, Francis (NIH/OD) [El Date: Thursday, April 30, 2020 10:58 AM To: Mascola, John (NIH/VRC) [El (b)( >; Lane, Cliff (NIH/NIAID} [El (bH ; Fauci, Anthony (NIH/NIAID) [El (b)(6)•> Cc: Tabak, Lawrence (NIH/OD) [El (b)( > Subje ct: FW: Respone ------~~ --------- Hi John, Cliff, and Tony, Ignore the silly part of the message be low, where (b)(5) -:-~============~ ~ . But let me ask you guys whether Francis From: Collins, Francis (NIH/OD) [E] Date: Thursday, April 30, 2020 10:55 AM To: Kadlec, Robert (OS/ASPR/10) -------..,,.,..., = ~======~~ Cc: Tabak, Lawrence (NIH/OD) [El (b)(6); Disbrow, Gary (OS/ASPR/BARDA) (NIH/OD) [El (b)(6) Subje ct: RE: Respone Bob, I I I I .: .. • • .. • • I • I • I I >; Shuy, Bryan (OS/ASPR/10) (b)( >; Johnson, Alfred I (b) (5) • I I• • I Francis From: Kadlec, Robert (OS/ASPR/10) (b)(6) Date: Thursday, April 30, 2020 10 :28 AM To: Gallo, Robert (b)(6)>; Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [El (b)(6)> ; Shuy, Bryan (OS/ASPR/10) -------- (bH6J; (b)(6) Subje ct: Re: Respone Dr Gallo thank you for your note and I appreciate you reaching out to me . I have copied Dr Collins and Dr Tabak to consider the ACTIV forum they have created to bring industry academia and government to consider scientific base approaches That you have described. Dr Collins has organized a vaccine group and I assesscould be the best and fastest place to discuss your concept. I am sure they will connect with you soonest Best Bob Kadlec. Sent from my iPhone On Apr 30, 2020, at 10:02 AM, Gallo, Robert ---------- (b) (6)> wrote: Dear Dr. Kaldec, I have not heard from you in over a week. You ment ioned getting back to me in a day or two. Time is passing. I am asking you to look at OPV 1 plus 3 serotypes as a bivalent, completely safe vaccine with powerful stimulation of inna t e immunity lasting several weeks, which can be given a second or thi rd time , and with a historical track record of preventing other infections from entirely differen t RNA viruses (such as protecting against influenza). Therefore, it should be really helpful for some mon t hs, and I think get us past a second wave of SARS-CoV-2, and help people return to work safely . I don't understand delays or apparent lack of inte rest. Who can possibly be against this? If you hear of hypothetical problems we can show you that these are fa lse. Just ask the questions, and we can give you the evidence . However , no answer from you suggests no interest and must quickly make alternative pathways. I am though quite surprised and fear you are receiving "fake news" if you will pardon the expression . Some have been against this who defend their old and failed position on polio eradication wit h their promotion of the use of the inactivated polio virus vaccine. Please note that in t he US between 1962 and 1985 we received (safely) the oral polio (OPV). Moreover, if vaccinated already there has not been a single case of a comp lication and BILLIONShave received it. No it will not last long as innate immunity is short lived, but we strongly believe that we can break the back of the SARS-CoVID-2spread. Also note that this is what Bill Gates is doing now in India and much of the Eastern hemisphere. There are countr ies outside the US wanting to move fast on this. We are wait ing for your reply. Robert Gallo Director, Institute of Human Virology, Professor of Medicine and Professor of Microbiology, UMB, School of Medicine, Baltimore, And Co-founder and International Science Adv isor of the Global Virus Network (GVN) (b)(6) From: Date: To: Subject: Attachments : Wed, 29 Ap r 2020 13:39:44 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: ASF: For review ASAP: draft Sec. Azar Remdesivir statement 4 29 20 remedesivir.docx, ATTOOOOl.htm Cann ot do right now. Go without me Begin forwarded message: From: "Billet, Courtney (NIH/NIAID) [E]" (b)(6) Date: April 29, 2020 at 1: 11: 19 PM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" Cc: "Routh , Jennifer (NIH/NIAID) [E]" (b)(6) , "Stover, Kathy (NIH/ NIAID) [E]" (b)(6) "Lane, Cliff (NIH/NIAID) [E]" (bH6) >, "Marston, Hil ary (NIH /NIAID) [E]" (bH6) >, "Conrad,Patricia (NIH/NIAID) [E]" (b)( >, "Folkers , Greg (NIH/NIA.ID) [E]" --------=-::-:-= (b)(6) > Subject: ASF: For review ASAP: draft Sec. Azar Remdesivir statement From: Fritz, Craig (NIH/OD ) [E] Date: Wednesday, April 29, 2020 10:38 AM To: Billet, Courtney (NIH/NIAID) [El -------= (b)( (b""" )("=" 6>r>; Stover, Kat hy (NIH/N IAID) [El (b)(6) Routh, Jennifer (NIH/N IAID) [ El (b)( > Cc: Burklow, John (NIH/OD) [El (b)( ; Myles, Renate (NIH/OD) [El (b)(6) ; Fine, Ama nda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; NIH News Clearance (NIH/OD) Subject: FW: For review ASAP: draft Sec. Azar Remdesivir statement Importance: High -------- Hi all - please let us know if you have any comments to the attached. Thanks ! Craig Fro m : Brennan, Patrick (OS/ASPA) (b)(6)> Date: Wednesday, April 29, 2020 10:33 AM To: Fritz, Craig (NIH/OD) [El CbH6J>; Burklow, John (NIH/OD) [El (b)(6)>; Myles, Renate (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El CbH >; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Charrow, Robert (HHS/OGC) (b)(6) Cc: Pence, Laura (HHS/ASL) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6);,; Pratt, Michael (OS/ASPA) (b)(6);,; Blakeman, Scott (05/ASPA ) (b)(6)> Subject: For review ASAP: draft Sec. Azar Remdesiv ir statement NIH and Mr . Charrow, Below and in the attached is a draft statement from the Secretary regarding the Remdesivir trial - please let me know as soon as you can if this looks OK. (I pulled the frontmatter from the NIH press release.) Thank you! - Patrick (b) (5) Patrick Brennan Director of Speechwriting Department of Health and Human Services Office: Cb)(6) I Cell Cb)(6) Frmn: Date: To: Eiubject: Attachments: Fauci,Anthony {NIH/NIAID) [E) Wed, 29 Apr 2020 01:56:42 +0000 (b)(6)v FW: DRAFTdocument for WH Briefing Tomorrow Development-Medical-Countermeasures-WH-B riefing 29 Apr il.pptx Here it is. From: Collins, Francis (NIH/OD) [E] Cb)( '> Date: Tuesday, April 28, 2020 8:08 PM To: Fauci, Anthony {NIH/NIAID) [E) (bH > Subject: FW: DRAFTdocument for WH Briefing Tomo rrow ------ == Hi Tony, Francis From: Mango, Paul (HHS/1OS) CbH6)> Date: Tuesday, April 28, 2020 7:26 PM To: Collins , Francis (NIH/OD) [E] CbH6)>;Kadlec, Robert (OS/ASPR/1O) CbH6)>;Fauci, Anthony (NIH/NIAID) [E] Cb)( >; Marks, Peter {FDA/CBER) CbH6);Woodcock, Janet (FDA/CDER) CbH >; Tromberg, Bruce (NIH/NI BIB) [E] CbH6) Subject: DRAFTdocument for WH Briefing Tomorrow -------::-,--:=, ----------- --------~~ Thank you all for your timely responses for contributions to this today. Please give this a look and let us know if there is anything glaringly out of place. We will have time to address edits du ring and after our 930am check in tomorrow. The Secretary may or may not use page 1 du ring his introdu ctory remarks. Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 18:14:04 +0000 To: Gibbo ns, Gary(NIH/NHLB I) [E] Cc: Koroshetz, Walt er (NIH/NINOS) [E); (b)(6) ;Auch incloss, Hugh (NIH/N IAID) [CJ (b)(6) ;Coll ins, Francis (NIH/ OD) [E) (b)(6) ;Tabak, Lawrence (NIH/OD) [E];Conrad, Patricia (NIH/N IAID) [E);Barasch, Kimberly (NIH/NIAID) [C] Subject: Thrombotic phenomena in COVID-19 From: Date: Gary: In follow -up of our recent conversation regarding the growing evidence that the extremely catastrophic course of many patients with COVID-19 seems to me pathogenically associated with the find ings of microthrombi in the lungs and often a mu lt isystem process resembling DIC. In addition, there have been growing numbers of cases of indiv iduals (some young and otherwise healthy) who have had unexplained strokes , only to find out t hat they actually have 5 COVID-19. I (bH ~ (b)( 5) I -----Best, l (bH 5 Thanks. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phon e: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Auchincloss, Hugh (NIH/NIAID) [E]on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 26 Apr 202017 :42:12 +0000 NIAIDODAM FW: Invitation to Webinar as keynote speaker. I wou ldn't think so. From: Secretary ARP (b)(6)> Date: Saturday, Apr il 25, 2020 2:07 PM ------To: Fauci, Anthony (NIH/NIAID) [El Subject: Invitation to Webinar as keynote speaker. --------- ~= (b)(6) To, Anthony S. Fauci, Office of the Director, Nationa l Institute of Allergy and Infect ious Diseases, National Institutes of Health, 9000 Rockville Pike, Bldg 31, Room 7A03, Bethesda MD 20892 Subject: Invitat ion to Webinar as keynote speaker. Dear Sir, On behalf of ASSOCIATIONOF REGISTERED PHARMACIST(An association working for Pharmacy Profession and having more than 2000 membe rs) in collaboration with Divine Internationa l, Gwalior (A Pioneer Pharmacy Institute) I am pleased to invite you to our Web inar having THEME "CHALLENGESAND OPPORTUNITIESFOR PHARMACISTIN THE PRESENTEPIDEMIC COVID-19" that will be held from 2nd May 2020 to 3rd May 2020. This Web inar is the get toge ther of Pharma professionals through the we b. The vision of this Webinar is to Aware, Prepare and strengthen our Pharmacy professionals in our country to th is epidemic COVID-19 for present and future aspect and exports more real istic ideas and present scenario of this epidemic COVID-19. You are one of the legends of Pharma Expert of our country, it is a great pr ivilege for us to see if you share yo ur experience with us, we rea lly expect and want t hat you join our Web inar and share with us th e great exper ience of you r life, we want to learn something from you so that we can create a great ideas, opportunity, and roll of Pharma profession al for our country in th e present scenario . We wou ld be pleased to have you present at th is point at this web inar to listen to what the role and importance in the Pharmacist advancement and thei r impact on our society and daily life we would also love to hear your thoughts and opinion about the Pharma professional that is a dream of our pharmacy fraternity . Therefore you are requested to send your recorded Lecture/ presentation of 30-40 min Sincerely, Thanks RajeshSinghJadon Secretary (National) Association of Registered Pharmacists Gwalior MP Mob: (b)(6) Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 15:43:25 +0000 From: Date: To: (b)(6) Subject: Attachments : From: RE (b) (6), (b) (4) (b) (6), (b) (4) --------------------------------- Date: Sunday, April 26, 2020 11:32 AM To: Fauci, Anthony {NIH/NIAID) [E]______ Subject: FW: (b) ( > """ (b"""" )(=6) (b)(6), (b)(4) To work on at home From: Ulrich, Connie M Date: Saturday, Apr il 25, 2020 2:35 PM To: Cynda Rushton (b)(6)>; Subject (b)(6) (b)(6) (b) (6), (b) (4) Hi Christine and Cynda, I finished my sectio n and unfortunately have to keep changing the COVID numbers! I will add some thoughts to the last section . Not sure how much we can add there but maybe some reflections would be helpful. Enjoy the sunshine today! I Best. Connie From: Date: To: Cc: Bee: Subject: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 02:57:3 1 +0000 Collins, Francis (NIH/OD) [El Tabak, Lawrence (NIH/OD) [E] Mascola, John (NIH/VRC) [El (b)(6) RE:agenda for Kadlec et al., Sun noon meeting -----~~ ------- Francis: Sorry that I took so long to respond . (b) (5)1,,., (b) (5) (b)(5) [ et us connect by phone first th ing in the A M> Thanks, Tony From: Collins, Francis (NIH/OD) [El Se nt : Saturday, Apr il 25, 2020 2:55 PM -----~~ To: Fauci, Anthony (NIH/NIAID) (El '°. ._______ (b) (6)·> Cb _H_~ ; Tabak, Lawrence (NIH/OD) (E] (b)(6)> Subject: RE: agenda for Kadlec et al., Sun noon meet ing (b) (5) From: Collins, Francis (NIH/OD) (El Date: Saturday, Apr il 25, 2020 2:49 PM To: Fauci, Anthony (NIH/NIAID) (El ------~~ (b)( 6) -------- (b)(6)>; Tabak, Lawrence {NIH/OD) [E) Subject: agenda for Kadlec et al., Sun noon meeting Hi Tony and Larry, For the meeting tomorrow at noon (currently invitees are Kadlec, Disbrow, Johnson, Woodcock, Marks , and us three), I would propose the following framework : (b) (5) (b)( 5) Thoughts? Tony , should Francis --------------------- (b) (5) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 01:22:2 1 +0000 Corey MD, Larry Conrad, Patricia (NIH/NIAID) [El -------------- RE: (b)( Let us talk tomorrow (Sunday). I am sorry that I did not get back to you today. From: Corey MD, Larry _______ Cb _) _(6) Date: Saturday, Apr il 25, 2020 5:36 PM To: Mascola, John {NIH/VRC) [E] ______ Cc: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Re: --,;(b""'"' H= > -------- --------------- Agree. ______________ (b)(6)!; Collins, Francis (NIH/OD) (E] (b)(6) _> Cb _ <_6l Sent from my iPhone On Apr 25, 2020, at 1:59 PM, Mascola, John (NIH/VRC) [E) wrote: ------ (b)(6) (b)(6)> seem reasonable Sent from my iPhone On Apr 25, 2020, at 15:54, Corey MD, Larry --------- (b)(6) wrote: A do have to say I am surprised . but ok From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6l; Mascola, John (NIH/VRC) [E) (b)(6)> Cc: Collins, Francis {NIH/OD) [E] (b)(6) Subject: Fwd: New England Journal of Medicine 20-13479 Let us discuss next steps Begin forwarded message: (b)(6) (b)(6) From: Date: To: Cc: Subjec t : Sat, 25 Apr 2020 13:05 :04 -0400 Collins, Francis (NIH/OD) [E) Tabak , Lawrence (NIH/OD) [E] Re: White House Task Force Briefing Monday (b) (5) On Apr 25, 2020, at 11:42 AM, Collins, Franc is (NIH/OD) [E] (b)(6): FC From: Collins, Francis (NIH/OD) [E) Se nt : Saturday, April 25, 2020 10:36 AM To: (b)( (OS/IOS) (b)( Cc: Tabak, Lawrence----:-:: (N"'."'. l".""'. H"7. /0::"". D :-:)-:[~E]:.====--------=[E] (b)(6)>; Pence, Laur a (HHS/ASL) Brian (HHS/10S) (b-:)(-:-= 6); Fauci, Anthony (NIH/NIAID) (b)(6J>; Wood, Gretc hen (NIH/OD) (b)(6) McManus, Ayanna (N IH/OD) [E] -------Subject: FW: White House Task Force Briefing Monday (b)( ; Harrison, (E] (b)(6J Hi Mr. Secretary, (b)(5)-Prn Glad to speak with you about how best to handle, if (b)(6) Francis (b)(5)-PCE (bX5)-PCI From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 14:25:16 +0000 Conrad, Patricia (NIH/NIAID)[E) FW: Italy Covid-19 La Stam pa is one of the two most important newspapers in Ita ly. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Mastro lilli Paolo Date: Friday, April 24, 2020 10 :08 AM To: Fauci, Anthony (NIH/NIAID) [EJ( Subject: Italy Covid -19 -------- 1, -------- Dear Doctor Fauci, My name is Paolo Mastro lilli, I am the US Bureau Chief for the Italian daily La Stampa. I am writing because we would appreciate very much the opportunity to have a phone or wr itten Q&As interview with you to discuss the Covid 19 pandemic. Considering the difficult situation Italy is experiencing, the help President Trump is send ing to Italy, and the plan to open America again, it would be very helpful for Italy to hear from your experience and competence t o address the Covid 19. We think that your advices would be very helpfu l to help our country and our citizens in dealing with the pandemic . We understand that you are very busy and this request has no deadline. La Stampa is a leading Italian daily, it is owned by the Agnelli Elkann family, owner of Fiat Chrysler as well. I am also a contributor for the Vatican Radio and the official news portal of the Holy See, I would share the interview with them as well, if you like. My cellphone number ief CbH 6Y Please let me know if you need any further information. Best regards Paolo Mastrolilli e II presente messagglo (inclusi gli allegati) contiene informazloni riservate esclusivamente al destinatario/ai destlnatari lndicato/i nel messaggio, ed protetto dalla legge. La diffusione, distribuzlone e/o la copia del contenuto del presente messaggio da parte di qualsias i soggetto diverso dal destinatario severamente vletata ai sensi dell'art. 616 c.p. e delle vigenti normative in materia di protezione dei datl personali . Se non siete i destinatari del presente messaggio, vi preghiamo di distruggerlo e di darcene immed ial a comunicazione inviando un messaggio di ritorno all'indirizzo e-ma il del mittente. e This message (including any attachments) contains confidential information inte nded only for the reclpient(s) named above, and is protected by law. Any disclosu re, distribution and/or copying of this message by any subject different from the named recipient(s) is strictly prohibited according to art 616 c.p, and to the applicable data protection laws . If you are not the intended recipient, please delete this message and inform us immediately about the deletion by sending a message lo the sender's e-mail address. From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 10:33:49 +0000 Holland, Steven (NIH/NIA ID) [E] Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] RE:Successful Submission of a Manuscript to Science (abc4208) To: Cc: Subjec t : Thanks, Steve. -----Original Message----From: Holland , Steven (NIWNIAID) [E] Scn t: T hur sday, April 23 , 2020 11:48 PM To: Fauci, Anthony (N1H/NIAlD) [E] _':======= Cc: Marston , Hilary (NIH/NJ AID ) [E] -----------:a-,-= -----(b)( (b =~~ - (6) ~ (b)( ; Lerner , Andr ea (NIH/NT AID) [E] (b)(6) Subject: FW: Successful Submission of a Manuscript to Science (abc4208) This is the acalabrutinibpaper today submitted to Science. NEJM was interestedbut wanted a month delay to be sure about the results but some of the authors (Not the NIAID one) balked and have gone elsewhere. Just keeping you in the loop. Steve Director, Divisi on of Intramural Research Nat ional Institu te of Allergy and Infectious Diseases National Institute s of Hea lth Bldg. IO/ l IN248 MSC 1960 Bethesda, MD 20892-1960 (b) ( voice .,. 3..,.. 0-l-..,. 4"'" 80 ,.... -...,. 45 ""'0,..,. 7 fax (b)(6) Assistant lab: Eva Portillo ____ ____ (b)(6) (b)( _,, voice Assistant to SD: Beth Schmidt _,, (b) (6) (b)(6) voice On 4/ 23/20, 1:59 PM, "Lionakis, Michail (Nll-1/NIAID) [E]" ________ (b _)_(6J _> wrote: Attached the submitted paper, which wil l be deposited to MedRx iv.org today I think. Mihali s On 4/23/20, I :34 PM, "science_editors@aaas.org" wrote: ManuscriptTitle: Inhibition of Bruton Tyrosine Kinase in Patients with Severe Covid-19 Author: Lionakis Manuscript Number: abc4208 Dear Dr. Lionakis: You are listed as a coauthor on the above manuscript,which has recently been submitted to Science. According to Science policy, all authors must have seen and approved the submission of their manuscript. If you have seen the manuscript and approved its submission, no action is necessary. Tfyou have not read this paper or do not approve its submission to Science, please let us know as soon as possible. Please refer to the manuscript number listed above in any correspondence (you can just reply to this message) . You can see the status of your manuscript at any time by logging into your account at the Science Journals Submission and lnfonnation Portal at https://cts.sciencemag.org. If you do not yet have an account, please go to https://cts.sciencemag.org/scc /#/ forgot-passwo rd and use the email at which you received this correspondence because that is linked to your manuscript. Then, follow the prompts to set your password and login. After login, you can access your manuscript and monitor its status. Once you are registered, we encourage you to link your account to your ORCID ID, an identifier that facilitates the correct attribution of your publications to you. To learn more about ORCID or to obtain an ORCID ID, visit their site at: http ://orcid.org. Your manuscript is now undergoing an initial screening to detennine whether it will be sent for in-depth review. If the manuscript is sent to review , its status will change to "To Review". Sincerely , The Editors Science From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Fri, 24 Apr 2020 01:58:36 +0000 Greg Folkers (b)(6) FW: HIVR4P postponed to 17-21 January 2021 FYI. See yellow highlighted request. From: HIVR4P- Secretariat Se nt : Thursday, April 23, 2020 11:23 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E~ ) -------~= (b) (6) > =======~ =;Dieffenbach, Carl (NIH/NIAID) [E] Subject: HIVR4P postponed to 17-21 January 2021 HIV RESEARCH FOR PREVENTION Cb.PETOWN SOUTHAFRICA·17-21JANUA'.-lV 2021 Dear Dr. Fauci , As the research commun ity responds to the global challenges of the COVID-19 pandemic, HIV prevention science matters as much as ever. Our priority as organizers of the HIV Research for Prevention (HIVR4P) conference remains the safety and wellbeing of all participants . After careful consideration, we have decided to postpone the HIVR4P conference to 17-21 Janua ry 2021 . Updated details for the session(s) are listed below : Session titl e: Sess ion type: Suggested presen tation title/topi c: Sess ion descr ipt ion: Session date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accompl ished ; Much to do -An overview on HIV prevention research Today's plenary sets the stage for the conference week ahead, outlining the big-picture chal lenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today , the opportunities and obstacles ahead and priorities for action moving forward . Monday, 18 January 2021 -16:00-18:00 Meet the Expert s lunches We invite you to host an informal table discussion at a Meet the Experts lunch on 20 January 2021 , 12:00-13:00. Daily meet the expe rts lunches provide early-ca reer investigators and community advocates with valuab le opportunities for informal , in-depth exchange with experts represen ting a cross-section of research issues, implementation challenges and HIV-affected communities. Please reply to this email by Wednesday, 6 May if you are still available to deliver this important presentation and, if so, please also include a photo and a brief biography. We are acutely aware many researchers and research organizations with critica l studies and submissions to HIVR4P are now also heavily engaged in the COV ID-19 response. Our hope is that postponing the confe rence , rather than presenting it virtually in October, will allow for the broadest participation to foster knowledge-exchange, debate and direction-setting in the field of HIV prevention research that HIVR4P is known for. Thank you for your consideration. Since rely , HIVR4P - Secretariat HIV Research for Prevention W: ------Avenue de France23 I CH-1202 GenevaI Switzerland (b)(6) HIVR4P Conferenc e 117-21 January 2021 I Cape Town , South Afri ca HIVR4P.org 0 @HIVR4Px 0 /HIVR4P From: HIVR4P- Secretariat Sen t : 21 February 2020 16:57 To: (b) (6) Cc: Bargavi Thyagarajan Subject: HIVR4P 2020 - Invitation to present ---------------------- (b)(6) HIV RESEARCH FOR PREVENTION UF>i OWN. ~JTH Af~ICA · 11-·&OCTOB~ 2020 Dear Dr. Fauci, We are writing with great pleasure to invite you to present at the 4th HIV Research for Prevention Conference (HIVR4P 2020 ) in Cape Town, South Africa, from 11-15 October 2020. HIV Research for Prevention is the only global scientific conference focused exclusively on the challenging and fastgrowing field of HIV prevention research. HIVR4P fosters interdisciplinary knowledge-exchange on HIV vaccines, microbicides, PrEP, treatment as prevention and biomedical interventions as well as their related socia l and behavioura l implicat ions . Details for the session(s) are listed below: Session title: Session type : Suggested presentation title/topic: Session description: Sess ion date and time: HIV prevention 2020 - Where are we now and where are we going? Opening plenary Much accomplished ; Much to do - An overview on HIV prevention research Today 's plenary sets the stage for the conference week ahead, outlining the big-picture challenges we face in research, product development and access to prevention . Speakers will provide diverse perspectives on the state of the field today, the opportunities and obstacles ahead and priorities for act ion moving forward. Monday , 12 October 2020 - 16:00-18:00 Meet the Experts lunches We invite you to host an informal table discuss ion at a Meet the Experts lunch on 14 October 2020, 12:00-13:00 . Daily meet the experts lunches provide early-career investigators and community advocates with valuable opportunities for informal, in-depth exchange with experts representing a cross-section of research issues, implementation challenges and HIV-affected commun ities. As an invited-speaker , you would be eligible to receive: • Complimentary conference registration ; • Roundtr ip economy airfare arranged through the HIVR4P travel agency; and • Accommodation at one of the hotels pre-blocked by the conference secretar iat. To accept this invitation , please reply to this email by Thursday, 27 February and include a photo and a brief biography . Please find also attached for your record the official invitation sig ned by the HIVR4P 2020 Co-Chairs. We ask that you please send any questions to the HIVR4P Secretariat at secretariat@hivr4p.org . Thank you for your consideration. We look forward to you joining us in Cape Town! Sincerely , From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Fri, 24 Apr 2020 01:30:49 +0000 blonda quir ico RE:estimation of dynam ics of COVID-19 in USA new simulations at 23 Apri l 2020 Thanks. From: blonda qu irico Se nt : Thursd ay, Apr il 23, 2020 5:02 PM To: Fauci, Ant hony {NIH/NIAID) [E] ------ (b) (6)> (b)(6 b -------- ~= (b)(6)>; COPPIET ERS'TWALLANT Yves Subject: est imat ion of dy namics of COVID-19 in USA new simulations at 23 Apri l 2020 Tony, We send you our simu lations. Best regards. Quirico Le mercred i 22 avril 2020 ecrit: a 00:09:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E) (b)(6) > a Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: blonda quirico Cb)(6) Date: Tuesday , April 21, 2020 11:18_ A _M ____ To: Fauci, Antho ny (NIH/N IAID) [E] ~~ Cb)( ; COPPIETERS'T WALLANT Yves (b) (6)> Subject: Re: estimation of dynamics of COVID-19 in USA new simulations at 21 April 2020 Tony, Professor COPPIETERS and I, we send you our new simulations : In summary, the USA COVID-19epidemic model says : - the final size of epidemic= more than 85061 0 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35520; - end of epidemic=+/- 19-28 June 2020 (we use two methods) ; - morta lity at the end of epidemic : ** if death rate 5% = +/- 42.530 deceased people (for the moment the death rate= 5%) ** if death rate 10% = +/- 85.060 deceased people You reached 91, 1 % of the theorical logist ic curve . Best regards . Quirico 00 32 475 48 68 42 Le dimanche 19 avril 2020 ecrit: Quirico : a 15:57:50 UTC+2, Fauci, Anthony (NIH/NIAID) [E] Cb)( > a Thanks again! Please keep this information coming to me. Best regards, Tony ------------ From: blonda qu irico Date: Sunday . April 19, 2020 5:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) -=-<'"= CbH >; COPPIETERS'T WALLANT Yves ------- Subject: Re: estimation of dynamics of COVI D-19 in USA new simulations at 18 April 2020 Tony, We send you our new simulations. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic = more than 779000 people infected and detected; - date of epidemic peak=+/- 7 April 2020 with theorical new cases - in one day during this peak - about +/- 35063; - end of epidemic=+/- 4-13 June 2020 (we use two methods); - mortality at the end of epidemic : ** if dead rate 5% = +/- 40000 deceased people ** if dead rate 10% = +/- 80.000 deceased people You reached 87 .5 % of the theorica I logistic curve. Best regards. Quirico 00 32 475 48 68 42 Le lundi 6 avril 2020 a 03:32:35 UTC+2, Fauci , Anthony (NIH/NIAID) [E]______ _>_C6) Cb _ > a ecrit: Dr. Bionda: Thank you for sending me this information. I appreciate it. Best regards, Tony From: blonda quirico .....,,.,=-e-..,,....,,-,,--,:,-,-,---- (b)( .... Date: Sunday , April 5, 2020 9:23 PM To: Fauci, Anthon NIH/NIAID) [E] -----~~ (b)(6)> (b)( >; COPPIETERS'T WALLANT Yves ------- Subject: estimat ion of dynamics of COVID-19 in USA Professor Anthony FAUCY, Sorry to disturb during the COVID-19 in USA. But I would you inform about the COVID-19 in USA. I'm medical doctor in Belgium. With my teacher Professor Yves COPPIETERS ( Ecole de sante publique - ULB Brussels) , we make simulations about the COVID-19 for many countries. In summary, the USA COVID-19 epidemic model says: - the final size of epidemic=+/- 462760 people infected and detected; - date of epidemic peak = +/- 1- 2 April 2020 with theorical new cases - in one day during this peak - about +/- 28390; - end of epidemic = +/- 15 May 2020; - morta lity : ** if dead rate 5% = +/- 23140 deceased people ** if dead rate 10% = +/- 46275 deceased people If you are interrested by our simulations, you can contact us. Best regards. Dr Quirico BLONDA (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 24 Apr 2020 00:50:12 +0000 (b)(6) Subject: FW: The Tablet I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. You have got to read this!!! --------- (b)(6)> From: Folkers, Greg {NIH/NIAID) [E] Date: Thursday, April 23, 2020 7:21 PM To: NIAID COGCORE ; NIAID OCGR Leg ; NIAID OD AM Subject: The Tablet I find myself thinking back to his fathe r, Stephen Fauci, whose drugstore our family relied on back in the 1950s. https://thetablet.org/only-in-print-dr-faucis-roots-in-dyker-heights/ ~ I 0,A™F uz, I jiQ!ftACi vs THE~LET Nt:WS O.PINIO.N PJUUSHa SCHOOLS SPORl'S AIIOUNI> THC OIOCES£ CCIIIONAVUtU.S Only in Print; Dr. Fauci's Roots in Dyker Heights :.,,,, a 2Q'20 D CJSCJ CATHOLIC NEWS SERVICE RiMQIOUS tOUcallon COfflinUtsin dlffnntfOffllal Ou!lnQPllldem.tC 81$hop" ,~ ~ IJ•Qt Peru to QU4td tnaigenou$ PlilOOI NudelltS $ J ,,t 20•ll 4uc• ,_.,,_ a1t11,,ucll00/l Pf~ FJU>er~ Ill U ~an t;,m ty OWNld • ,,..g1,bomood pl,.rmKf ,n Oy/(fl' i-.gt,ta/ ISa 19$4 f}<8<1,;atecl tl>t Jew.I WtOOI(Phelo COIIIWf of FIM:I t;Jm#f) From the Neighborhood by Frank Derosa Frank DeRosa retired as Associate Publisher of The Tablet and director of the Diocesan Public Information Office in 2008 When I see Dr. Anthony Fauci on the TV screen explaining expertly everything we need to know about the coronavirus pandemic, I find myself thinking back to his father, Stephen Fauci, whose drugstore our family relied on back in the 1950s. Steve Fauci was the neighborhood pharmacist. The Fauci Pharmacy stood on the southwest corner of 13th Ave. and 83 rd St., in the Dyker Heights section of Brooklyn, diagonally across from the Shrine Church of St. Bernadette. We lived two blocks away on 85 th . Long ago parishioners like me remember what the store looked like, the soda fountain that ran along the right wall, the telephone booths at the left close to the entrance and the counter straight ahead down the center. Whenever my mother sent me there, Mr. Fauci would be behind the counter, but it was a family enterprise. They lived in an apartment above the store, and if the patriarch wasn't serving you, his wife, Eugenia, or daughter, Denise, was there. Young Anthony, I've since learned, pitched in too, his father sending him out on his bike to deliver items to customers. I've never met the man who has become the most important medical voice in the country. Nor have former parishioners that I've spoken to about him in recent days, like boyhood pals Anthony LoFrisco, from 80th St., now in Connecticut, and Bob Orlando, who lived on 84th, now a New Jersey resident, as well as Bishop Gerald Barbarito of the Palm Beach Diocese, from 11th Ave. But each remembers the pharmacy as a Dyker Heights institution. While we don't know him personally, in a sense he's become everyone's friend. With his steady television presence, he's imparted his vast knowledge and straightforward advice in a trademark, sometimes gravelly or raspy, Brooklyn accent that has endeared him to people far and wide. You can't be anything but proud of someone of his prominence who came from the parish. Anthony became known as Tony, as he tells it, when Father Flanagan, principal of Regis High School, decided to call him that on his first day as a freshman. The name stuck. Tony took buses and trains to the Jesuit school in Manhattan, including the old Sea Beach Express. He traveled 70 minutes each way, did three hours of homework, captained the basketball team and excelled in the classroom. I remember hearing that when Tony was a high schooler, he had a parttime job working in St. Bernadette's rectory, answering the phone and doing whatever else parishioners wanted him to do to put them in touch with one of the parish priests. In those days, the rectory had a priestly bonanza. There were four of them. Because St. Bernadette's School had not yet been established, Tony went to Our Lady of Guadalupe School, where he was taught by Dominican Sisters. It was, and is, St. Bernadette's neighboring parish. Like most kids, he loved sports. He played CYO baseball and basketball. At Dyker Park on 86th St., he and his friends developed skills in imitation of their heroes. A Yankee follower living in the midst of Brooklyn Dodgers fans who adored The Boys of Summer, he's said his favorite players were Joe DiMaggio and Mickey Mantle. Tony's father and mother married at 18, after they graduated from New Utrecht High School. Steve went on to Columbia to study pharmacy. Sometime after he opened his pharmacy, he became friends with Father Al Varriale, one of St. Bernadette's beloved parish priests. At one point, Steve, as a parent, and the priest known as Father V, who directed the parish's robust CYO sports program for youths, shared a concern. It was the easy availability of indecent and immoral publications that they knew was a threat to the moral development of young people. So, with the approval and support of the Diocese of Brooklyn, together they formed a diocesan commission against pornography. Both men are now long gone, and so is the commission, but it was a good idea, though it did not survive them. Remarkably, just a few houses up the block from where Steve established his pharmacy, lived the Pellegrinos, another family of St. Bernadette's parishioners that produced a renowned medical professional. The eldest son, Edmund, became a bioethicist, a "preeminent" one, as one newspaper described him after he died. But he was more. He helped develop medical programs at Kentucky, Stony Brook and Tennessee Universities. Later, he took on the presidency of The Catholic University of America. Then, after completing his tenure there, he became, as physician and philosopher, the director of the Kennedy Institute of Ethics at Georgetown University. Though years apart in age, both Dr. Fauci and Dr. Pellegrino became Hippocratic stars, nurtured on the same block. Only in Brooklyn, I say, not without bias. Steve Fauci was known by members of his extended family and friends for his personality, kindness, sense of humor and wit, and for telling good stories. So they said in comments after he died in 2008. Tony appears to have inherited Steve's gene for lightheartedness. His daughter once told the Washington Post that her dad could be a "goofball ... he works hard and does his thing, but he comes home and he's singing opera in the kitchen and dancing around." That kind of calm can help a man maintain his balance as he deals with the pressure of talking to millions of people every day about the complexity of a global pandemic. As one newsman said, "When Fauci appears on the screen, you turn up the volume." He once said the Jesuits at Regis and Holy Cross College taught him the importance of "precision of thought and economy of expression." That's what he delivers every day: accurate information given concisely. That's Tony Fauci, now a national treasure. And to think, he came from the neighborhood. Dr. Anthony Fauci TOSLOW EAD He graduated from Regis High School and the College of Holy Cross. He graduated number one in his class at Cornell Medical School in 1966. He completed his medical residency at New York Hospital In 1984, he became director of National Institute of Allergy and Infectious Diseases, a position he holds today. Front row, kneeling U.it1lc \ or Cr~ l r-,,,.,, St~\, was on Date: Thursday, April 23, 2020 8:31 PM To: Fauci, Anthony {NIH/NIAID) [E] ------ Subject: ~= -------Another Possible Tool in The Fight Against SARS -CoV-2 (b)(6)> ? Dr. Fauci---Forgive the crude and unsolicited manner in which I am attempting to reach out to you but I don't reall y KNOW any other way! I am not a medical doctor nor am I a principle investigator. I am just a Cytologist employed in the Anatomic Pathology department at LA County-USC Medical Center here in Southern California. But I have been read ing a lot- -- and in my own exploration I have come across several articles which suggest the possibility of using a class of agents called SPHINGOSINE-1-PHOSPHATERECEPTOR AGONISTSin combination with antivirals like oseltamivir (or perhaps Remdesivir?) to treat both the viral pathogen responsibl e for the current pandemic as well as the runaway immune response of the host leading to the oft fatal cytokine storms. Apparently these compounds have been approved for flare-ups of multiple sclerosis, and have even been tried on Alzheimer's patients. The commonly known drug is FINGOLIMOD. But these papers that I have cited for you below seem to indicate that structural analogs of this compound could be important in damping down the dysregulated pro -inflammatory cascades which seem to be leading to DIC, alveolar exudates and diffuse alveolar damage, capillary leak syndrome and ultimately the multiple organ failure that is killing an unacceptably high number of people. The fly in the ointment Dr. Fauci here is that these 5-1-PR agonists have only been demonstrated to be effective in non-human primates and other mammals. And much of these studies on these compounds has been done not on coronaviruses but on influenza viruses . So it would be a gamble. But is that not how we have learned much about human health and disease is by the gracious sacrifice of our anim al cousins? And might it not be a general effect that these sphingosine derivat ives have on viral sepsis so that maybe what works for influenza might work for the coronavirus? In the dire situation that many of the most critically ill COVID 19 patien ts find themselves, it seems they are on the pr ecipice of a rapid demise once they begin to show certain key laboratory resu lts---(sp ikes in 0-DIMER, C-Reactive Protein, Serum Ferritin, prolongation of prothrombin and APTT, increased card iac troponin 1, surges in IL-6, IL-7, monocytic and macrophage chemo-attractant cytokines etc) . W ith pat ients isolated by these aberrant lab values, the window may be narrow but it may be a time where application of antiviral compounds in combination with t hese inflamma t ory mod ulat ors could have a striking impact on mor t ality? Indeed maybe even TWO different antivirals with diff ering mechan isms of action in combination with these S1-PRAgonists would even be better. And the possibilit ies of other combinat ions of course would be there for further exploration . Fully cognizant of the Hippocratic Oath to 'first do no harm' I still believe that at least the medical rat ionale is sound for the inclusio n of these agents int o the possible arsena l of therapeutics for the more severe COVID 19 patients. Please refe r below to t he st udies I found particularly helpful or promis i ng. Perhaps yo u can put together some 'teams ' to further explore investigate these opt ions?? We all appreciate everyt hi ng you have done, and continue to do ! Gary Radin https://www .sciencedirect.com/science/article/pii/S0140673620303056 https ://www.pnas.org/ conte nt/108/29 /12 018 https://www .clinical key .com/# !/con tent/p layContent/1-s2. 0S0042682214000063 ?return ur l=http s:%2F%2Flinkinghu b.elsevier .com%2 Fretrieve%2Fpii%2FS0 042682214000063%3Fshowall%3Dtrue&referrer= Suppression of cytok ine storm with a sphingosine analog prov ides protection against pathogenic influen za virus I PNAS Human pandemic H1N1 2009 influenza virus rapidly infected millions worldwide and was associated with significant mortality. Antiviral drugs that inhibit influenza virus replication are the primary therapy used to diminish disease; however, there are two significant limitations to their effective use: ( i) antiviral drugs exert selective pressure on the virus, resulting in the generation of ... www.pnas.org https://www.thelancet.com / journals/lancet/article/PIISOl 40-6736(20)30566-3 /fu lltext 1 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study - The Lancet The potential riskfactorsof older age, high SOFAscore,and d-dimer greater than 1 µg/ml could help cliniciansto identify patientswith poor prognosisat an early stage. Prolongedviral shedding providesthe rationalefor a strategy of isolationof infected patients and optimal antiviral interventionsin the future. www.thelancet.com https://www.ncbi.nlm.nih.gov /pmc/articles/PMC317 6439 / Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection PubMed Central (PMC) Cytokine storm during viral infection is a prospectivepredictor of morbidity and mortality,yet the cellularsources remain undefined. Here, using genetic and chemicaltools to probe functions of the S1P 1 receptor,we elucidate cellularand signaling mechanisms important in initiating cytokine storm. While S1P 1 receptor is expressedon endothelial cells and lymphocytes within lung tissue ... www.ncbi.nlm.nih.gov From: Fauci, Anthony (NIH/N IAID) [E) Date: Thu, 23 Apr 2020 22:47 :07 +0000 To: Billet, Courtney (NIH/N IAID) [E];Greg Folkers Patricia (NIH/NIAID ) [E];Routh, Jennifer (NIH/NIAID) [El Cc: Barasch, Kimber ly (NIH/NIAID) [C] Subject: FW : Sammies recognition th is year - congratulations Attachments: AFauci, NIH.pdf ---------- (b)(6} ;Conrad, Please take a look at this and let us discuss. Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Max Stier Date: Thursd ay, Apr il 23, 2020 2:57 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Barasch, Kimberly (NIH/NIAID) [C]_________ --------,;- = (b)( 6)> Cb _H_ ; Sammies Subject: Sammies recognition t his year- congratulat ions Dr. Fauci: I hope you are healthy and well. The Partnership for Public Service is honored to inform you that we have selected you as a fi nalist for the 2020 Samuel J. Heyman Service to America Medals, otherwise known as the Oscars of government service. You were nominated by Francis Collins for your o utstanding career at NIAID and th e wor k you are currently do ing on behalf of th e American people to prepare, inform and protec t lives in our country and around the wor ld during th is uncertain time . Your work truly embod ies th e best of governm ent tha t we strive to recognize through t he Sammies program. Attached, I've included the profi le we have drafted to summarize yo ur work and accomplishments both for recognizing you as a fina list and for having the select ion committee vote for the award recipients . Should you have any edits or wish to add a personal quote, please send those to us at your convenience. We will be releasing your profile publicly with the rest of the final ists on Sunday, May 3 . Again, thank you for the work you do on behalf of the NIH and our country. Best, Max Stier President and CEO Partnersh ip for Public Service Fauci, Anthony (NIH/N IA ID) [El Thu, 23 Apr 2020 22:37 :35 +0000 To: Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Subject: FW: NAS Annual Meet ing Session on COVID-19 -- Information regarding your Satur day April 25 part icipation From: Date: FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of it s representatives. From: Dzau, Victor J. Se nt : Thursday, Apr il 23, 2020 1:49 PM To: Fauci, Anthony (NIH/NIAID) [E] ----------------~~ (b) Cc: Hannon, Emma ; Conrad , Patr icia {NIH/NIAID) [El (6); (b)(6) 'ben.t inker@cnn .com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Kh air zada@t urner .com' ; 'Tia.Mille r@turner.co m' ; (b) ( >; McGinni s, J. Mic hael ; (b)( (b)(6) ; Mu n, Jenny ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regard ing you r Saturday April 25 part icipation ------; ~,s, =======~ -------- Dear Jeremy, Tony, Sanjay, George, Susan, and Richard, I'm really look ing for w ard to th is panel on COVID-19 at the NAS Annual Meeting on Saturday, April 25th at 2:00 -3:3 0 pm ET.There is tremendous excitement and enthusiasm, and registr ati on is thr ough the roof . I am sending this note to do a last minute check to see if there is anything you need from me. I also want to check whether you are planning to use slides. Will you be sending your slides to us to project or use the share screen feature to advance your own slides? Regardless, it would be helpful to me if you could send me your slides for my preparation. I wou ld greatly appreciate it if you would respond to th is email. Best, Victor ------ PS, Cb)~ , my special assistant, will be sending you additional information about the session logistics shortly. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM ---------------~ ~ (b)(6)>; Hannon, Emma ; ---:---:-:--:-:--:-:---:-======:...;_--=~ (b)(6)>; 'T.MillerdeVega@wellcome.ac _________ .. =========.~;;;--:-:-'conradpa@niaid.nih.gov ' .uk' 'jsi@cepi.net ' (b)(6) 'rebeka.yasmin@cepi .net' (b)( 6) >; 'b en.tinke r@cnn.com' ; 'Amanda.Sealy@cnn.com' ; 'Neel.Khairzada@turner .com' ; 'Tia.M iller@turner .com' ; (b)(6) Subject: RE: NASAnnual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation (b)(6)>; Dear all, Thank you for agreeing to participate in a spec ial late breaking session on the COVID-19 pandemic at the NAS annual meeting . Knowing how busy you are, I am sending this ema il in lieu of a call to prepare for the session. As you know, this is a 90 minute sess ion which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response . I plan to hold an engaging discussion that covers the whole experience on dealing with this pandemic - from US to internat ional, to preparedness and response , the biology of the virus, the state of diagnostic , treatmen t and vaccine development, and the importance of communication. I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for ilJustrat ion. I hope that each panelist will provide their own perspective and spea k to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss tbe US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019 - 20 coronavirus pandemic. • George Gao will discuss China's responseto the pandemicand lessons learned for the rest of the globe. • Susan Weiss will discuss the viral characteristicsof SARS COV2 , insights into its pathobiology , immunity and developmen t of a pan-CoV antiviral. • Richard Hatchett will discuss the deve lopment of new vaccines and treatments against COVID-19. • Sanjay Guptawill commenton the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. Followingremarks from each panelist, we will have a moderateddiscussion amongst ourselvesI will ask you a set of questions (15 mins) and then we will take questions from the web (25 mins) . To prepare me to be your mode rator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, Apri l 8, 2020 10:56 AM (b) (6) ; --------------------------- 'ben.tinker@cnn.com'; 1Amanda.Se aIy@c n n.com'; 'Neel.Khai rzada@turne r.com' ; 'Tia.Miller@turn er.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday Apri l 25 participa t ion (b)(6) Dear Speakers: I am t he logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have pro vided additional details below. Please note that the session w ill be live w ebcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We w ill need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your review and submission. Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below . If this is incorrect, please let me know . Anthony S. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, Wellcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications. I am attaching a 'speaker guidelines' f ile in case you have any questions on how best to prepare for and stage your remote talk . We have technical staff available to help you become familiar with Zoom and its settings -such as "sharing your screen" (if you have slide presentations that need to be shown during your talk). We can arrange for a t raining session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************* ************* Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: [El Subject: ----- Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:36 :33 +0000 Cassetti, Cristina (NIH/N IAID) [E);Lerner, Andre a (NIH/NIA ID) ;Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/N IAID) [El FW : New sheet COVID.docx -=-a=, (b)(6) Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-O3 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Dani Bolognesi, Ph.D. Date: Thursd ay, April 23, 2020 1:01 PM To: Fauci, Anthony (NIH/ NIAID) [El Cc: Conrad, Patr icia (NIH/ NIAID) [E] Subject: FW: New sheet (b)( 6) ------== ~=======-~ = Hi Tony : I hesitate to bother yo u with th is as I am sure that you are inundat ed w ith requests of this sort over and abov e everyth ing else you are do ing whic h is tr uly magnific ent. I beli eve th at th ere is something of potentia l importance in what is commun icated below but you are in the best position to tell me wh ethe r it could fit in the toolb ox you are assembling for COVID 19 in both th e short and longe r term . I have to acknowledge our fr iend Bob Gallo for triggering this (b) (4) (b) (4) Reaching out to you to see if you think this approach has merit. Since your time is so precious, I do not expect you to review this but perhaps you can forward to one of your trusted colleagues. PPS. loved the interview with Coach K! Con un forte abbraccio I Dani From: Date: To: Subject: Min imized Coro naviru s Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 22:25 :14 +0000 (b)( 6) FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump I MSNBC http s://bit. ly/2yynEPf I may have already sent this to you, but I do not think so. It is short (6 minutes) but it has a segment that shows me 37 years ago. Yikes!!! You will get a chuckle. Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- (b)(6) From: Barasch, Kimber ly (NIH/NIAID) [CJ Date: Thursday, April 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it.ly/2yyn EPf ------~~ -------- Kim Barasch [Cl Office of the Director National Institute of Allergy & Infectious Diseases (b)(6) (b)(6) (b) (6)> From: Folkers, Greg {NIH/NIAID) [E) Date: Tuesday, April 21, 2020 11:06 PM Subject: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing- Long Before Trump Minim ized Coronav irus I MSNBC https :ljbit.ly /2yynEPf -------- Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 22:14 :31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses Scientists_to_Stop_COVID19_2020_04_23_FINAL.pdf Email below from David Liu. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone (b)(6) Email: (b)( From: David Liu (b)( Se nt: Thursday, April 23, 2020 6:01 PM To: Collins, Francis {NIH/OD) [E] (b)( >; Fauci, Anthony {NIH/NIAID) [E] (b)(6); Lane, Cliff (NIH/NIAID) [El (b)( >; Austin, Christopher (NIH/NCATS) [E] (b)(6 )'>; Whalley, David (FNIH) [T] (FNIH) [T] (b)(6); Tabak, Lawrence (NIH/OD) [El Cc: Michael Rosbash (b)(6)>; Ramnik Xavier (b)(6)>; EDWARD SCOLNICK (b)(6); Stuart Schrei ber (b)(6)>; Michael Z Lin (b)( 6) >; Ben Cravatt (b)(6J>; Thomas Cahil l (b)(6) R. Scott Kemp (b)(6) Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses ------=-::-:-= __:....:......:..!::::====~~ '.=========~-= = ":"'""~----:~----:.==::....;.-=-:~ -----~=--- Dear Francis, Anthony , Cliff, Christopher, David, Maria , and Lawrence, I hope you are all well. Attached is the updated set of four proposals on: 1) Rapid repurposing of antiviral drugs to treat COVID-19; 2) Expedited development of neutralizing monoclonal antibodies to t reat COVID-19; 3) Rapid COVID-19 vaccine development; 4) Risk-reduced ways to reopen schools and businesses, and the healt hcare system changes that are needed to enable them. We hope you find these updated proposals useful , and would be happy to engage in any way that could be helpful. Sincerely yours , Ben Cravatt (Scripps), Lynn Goldman (GWU),Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash(Brandeis), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merk in Institute ofTransformative Technolog ies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of th e Natu ral Sciences and Prof essor of Chemistry & Chemical Biology, Harvard Unive rsity 75 Ames Street Cambridge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [E] -------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partnership called ACTIV (for Accelerating COVID-19 Therapeutic Interve ntions and Vaccines), but it has t aken on most of the points you raise in sections 1- 3 of your letter. I share your hopes that remdesivir will show benefit, and the current large NIH-sponsored RCT has completed enrollment and shou ld reveal results in about a month. But of course we want to t est multiple other interventions - both small molecules and antibody-based therapies, so we need our tria l system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prioritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with full engagement by FDA). Best regards , Francis From: David Liu Cb)(6) Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)( •>; Collins, Francis(NIH/OD) [E] (b)(6) (b)(6)>;Ramnik Xavier Cc: Michael Rosbash --------...!::===~~----___,. -----":'"":'~~---:::====== (b =):;:(~;~EDWARDSCOLNIC _K --=====~~ Schreiber -----=== (b 'a's ~::;(6) ~---- (b)(6)>;Michael Z Lin ~= CbH ; Ben Cravatt Subject: A proposal to stop COVID-19 and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen -scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposa Is (attached) to produce safe and effective COVID-19 therapeut ics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces the risk of future COVID-19 outbreaks . We hope you find these ideas interesting, and might be willing to share this set of proposa ls with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through emai l routes that his standard inbox may be too overwhelmed for our proposa l to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an ant iviral drug to treat COVID-19 patients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individua ls; (3) How to develop COVID-19 vaccines on an expedited t ime scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michae l Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Mer kin Institute of Transformative Technolog ies in Healthcare Director of th e Chemical Biology and Thera peut ic Sciences Program Core Institut e M ember and Vice-Chair of th e Faculty, Broad Institute Investigator, Howard Hughes Med ical Instit ute Thoma s Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:47 :13 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Whit e House Coronavir us Task Force M eet ing - 4.24.20 FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 21:40 :33 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Updat e: Wh ite House Coronaviru s Task Force M eet ing Heads-up! Change in schedule for t omorrow. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (bX5) -l'U Fauci, Anthony (NIH/N IAID) [El Thu, 23 Apr 2020 21:29 :50 +0000 To: Fauci, Anthony (NIH/N IAID) [El Subject: FW: MSNBC: See Dr. Fauci's Stunning Pandemic Warn ing - long Before Trump Min imized Coro naviru s I MSNBC http s://bit. ly/2yynEPf From: Date: https://bit. ly/2yyn EPf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barasch, Kimberly (NIH/NIAID) [C] ---------- (b)(6) Se nt : Thursday, Apr il 23, 2020 9:04 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: MSNBC: See Dr. Fauci's Stunni ng Pandemic Warn ing - Long Before Trump Mi nimized Coronavirus I MSNBC https ://b it .ly/2yyn EPf ------~~ -------- Kim Barasch [CJ Office of the Director National Institute of Allergy & Infectious Diseases (b)( 6) (b)(6) From: Folkers, Greg (NIH/NIAID) [E] --------- (b)( 6)> Date: Tuesday, April 21, 2020 11:06 PM Subje ct: MSNBC: See Dr. Fauci's Stunning Pandemic Warning- Long Before Trump Minim ized Coronavirus I MSNBC https://bit .ly/2yynEPf Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. Tt does not necessarily represent my views nor those ofNTAID, NIB , HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Thu, 23 Apr 2020 14:34 :36 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Thank you, and... image002.png, ATT0000l.htm, PasstheMic Expert Outreach.pdf, ATT00002.htm Let us discuss Beg in forwarded message: _________ .. From: Gay le Smith Date: April 23 , 2020 at 1:49 :04 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ----------=:--:--:-=(b)(6) Cc: Tom Hart Subject: Thank you, and ... Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American, a former colleague, a long-time admirer and student of your wisdom - thank you. We are all safer because of you, and the world will be a better place because of you. Again. As you know , I am now leading the ONE Campaign. We' ve been quite active wi t h the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Africa . We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of t he places we work. It won't surp rise you that of particular urgency amongst our partners in Africa is that facts and information get to people across the continent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we will ask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to ta lk about the critical elements needed to flatten the curve and slow t he spread. Or Idr is Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have t he answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact . As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turn ing over their platforms for the day, celebrity influencers will be donating one of their biggest assets - their followers - to YOU,giving you the platform you need (and we all need) to tell the world why a global response is critical. Because none of us are safe until all of us are safe. We wi ll work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North America, Europe and Africa, and help create content that both part ies are happy with . We are now confirming our talent partners, and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact wou ld be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions . Ideally we would like to get this off the ground in early May, so are hoping to confirm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do . All my best to you, Gayle Gayle Smith ONE.ORG I President & Chief Executive Officer I------- (b)(6) I Twitter I Facebook I lnstagram ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that eve ryo ne, everywhere can lead a life of dignity and opportunity . From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 18:25 :56 +0000 Simmon s-Butler, Kirk (NIH/NIA ID) [C] Re: Thank you Dr. Fauci! image001.png , image002.gif To: Subject: Attachments : Kirk: Thank you for yom· kind note. Much appreciated. Best regards , To ny On Apr 23, 2020, at 2:16 PM , Simmons -Butler , Kirk (NIH/NIAID) [C] Cb)( wrote: Greetings Dr. Fauci, I just wanted to take a moment to personally thank you for all of your support and leadership during these unprecedented times. I am proud to be a part of the NIAD family and you represent us and the country well ! God continue to bless and keep you and your family! Thank you again sir! Regards, Kirk Kirk D. Simmons-Butler, M.S. Assistant Facility Manager 14DNR. Charles River Laboratories Inc. NIH/NIAID ----~~ (Office) (b)(6) (fax) (301) 761-6013 Charles River website - www.criver.com The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storagedevices. The National Institute of Allergyand Infect iousDisease(NIAID) shallnot acceptliability for any statement made that are the sender'sown and not expresslymade on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Friday, March 27, 2020 11:55 AM To: NIAID Announcements Subject: Platelet Donations Down are Down Amid Coronavirus Outbreak -- Please Donate Dear Colleagues: The NIH Platelet Donor Center has an urgent need for healthy individuals to give lifesaving platelets to patients. The need for platelet donations is especially acute now with the coronavirus pandemic. While social distancing and increased telework are necessary to contain and slow the spread of coronavirus, we have seen a marked decline in platelet and blood donations for our patients. To alleviate this shortage, NIAID and the Department of Transfusion Medicine (DTM) are co-sponsoring a two-week Platelet Drive from March 30 -April 10. Platelet collections, as well as whole blood and Double Red Cell donations, can only be made at the NIH Blood Bank on campus in Building 10, Room 1(713 Monday t hrough Friday from 8 :00 am to 5:00 pm. The Platelet Center at Fishers lane is temporarily closed and plate let collections are now on the main campus through at least the next 30 days. This move helps to ensure that blood donors are protected by visitor screening, minimizing possible exposure to individuals at risk. What is a double red cell donation? A double red cell donation enables donors to donate two units of red blood cells in one visit. During a procedure called apheresis, whole blood is separated through a cell separator and red blood cells are collected. The remainder of the blood components are returned to the donor along with saline to replace the lost volume. I encourage participation of all employees who are eligib le to provide a donation to benefit our NIH patients. I understand employees may be hesitant to participate under the current conditions, but I would like to reassure you that blood donation is a safe process. Additiona l precautions have been put in place at our Blood Bank to help prevent the spread of infection and protect the health of donors and staff . Thank you to all who support our quarterly platelet drives. Your efforts provide a lifeline for our patients . Those who participated in the last drive are now eligible to help once again. In appreciation of your dedication to helping others, NIAID grants admin istrative leave to any NIAID federal employee who donates platelets at the NIH Blood Bank. Specifically, you will be granted 4 hours of administrative leave to be used immediately following your platelet donation appointment. As always with such activities, please notify your supe rvisor for approval prior to donating at the NIH Platelet Center .. Contractor employees should speak directly to their contract companies to determine what leave options are available . Please contact the Donor Center at 301-496-4321 to schedule your appointment. let the Donor Center staff know you are with t he NIAID Platelet/Double Red Cell Drive. They will answer eligibility questi ons and provide information about the donation process. Thank you for consider ing donat ing during t his stressful t ime. Best regards. Sincerely, A.S. Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone (b)(6) FAX:(301) 496-4409 -------- E-mail: (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID)shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAI D by one of its representatives. ~ CHARLES RIVER lABOAATORIES From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 23 Apr 2020 17:39 :48 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Subject: FW : Wellness Initiat ive Proposal Attachme nts: Wellness ln iti ative_POC_Sundar .zip, Wellness Initiative Proposal_Sundar .pdf, Managing Anxiety Around COVID-19 March 27 {007) .pdf --------~~ ---------- Please take a look at th is and handle. ---------------- ~= From: Sundar, Sachin {NIH/NIAAA) [F] Date: Thursday, April 23, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Subject: Wellness Initiative Proposal (b)( > (b)(6)> Dear Dr. Fauci, I have an idea regarding science commun icat ion and wellness . Here's a rough proposal and proof of concept . At fu ll effect , I think it could have noteworthy potential. (b) (5) Thank you for your time . Respectfully, Sachin Sundar From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:25 :22 +0000 Stephen L. Hoffman RE:Follow Up Thanks Thanks, St eve. I appreciate your not e. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stephen L.Hoffman Date: Wednesday, April 22, 2020 9:56 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Follow Up Thanks -------::-::-:-= (b)( > Dear Tony, I hear continuously from people from all walks of life how grate ful they are for your presence on the COVID-19 team . You are perform ing an incredible service to our country and the world. Thanks again, Steve Stephen L. Hoffman, M .D. Chief Executive and Scientific Officer Sanaria Inc. 9800 Medical Center Dr. ste 209a Rockville MD 20850 tel: (b)(6) (work) tel : (bH (mobile) fax: 301-770-5554 E-Mail: slhoffman@sanaria.com www .sanaria.com From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 13:00 :55 +0000 Redfield , Robert R. (CDC/OD) All ison Arwady ;David Barr;Conrad, Patr icia (NIH/N IA ID) [E) FW: Dr. Fauci asked m e to send Chicago question Workforce _ Proposal_ Chicago_Ap ril2020. pdf Bob: Please take a look at this . This question evolved from a te leconference that I had 2 nights ago with people "in the t renches" including Alison Arwady (Chicago ). The question is what w ill be the relationsh ip between the public health workforces at the federal and local levels. Youi had spoken of the CDC people that will be assigned locally and that will help build up a local workforce. How will COD interact and relate to the locals. Is there any possibility of Federal funding of their proposal (see attachment). If not, do you have any suggestions for them? I can discuss this with you today at the Task Force meet ing. Thanks. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496 -4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) Date: Wed nesday, Apr il 22, 2020 3:53 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: Dr. Fauci asked me to send Chicago question -------------- Pis advise . (b)(6) ..,.....,...= From: Allison Arwady Date: Wednesday, April 22, 2020 3:42 PM To: Conrad, Patricia (NIH/NIAID) [E]________ --------~ (b)(6) = Cb _>_<.,.> Subject: Dr. Fauci asked me to send Chicago question Dear Patty, Last night on his call with public health leaders from cities across the country , Dr. Fauci asked me to send him/you my follow -up question from Chicago: How will the necessary public health workforce expansion (e.g. for wide-scale case investigation, contact tracing, linkage to care, community testing, and vaccination) be supported at the federal leve l? Our unders tanding is that state or local ju risdictions will be able to deve lop their own workfor ces rather than supporting a single workforce at the federal level, and we agree with this approach , but it would be very helpfu l to understand next steps and potential timelines, particularly as the reopening drumbeat gets louder. For example, Chicago has developed a local plan/proposal (attached) that would meet our local needs, help address some of our underlying race and economic equity concerns, and build on our existing community and clinical partnerships. We have shared it with some partners, but it is not at all clear how/whether/when/how much funding might be available. Given the need to quickly expand our workforce and plan ahead, it would be very helpful to get a sense of: a. How much funding/support might be available, and how that will be determined b. Whether funding might come through HHS/CDC(our preferred mechanism), FEMA, or another mechanism c. Will support be available in weeks or months ...and for how long-we are strongly advocating for 5 years, similar to what was done for Ebola d. Any other information about how our local or state plans need to be adapted to fit into federal thinking on this approach Thank you so much; I deeply apprec iate Dr. Fauci taking the time to meet with us directly and hear our concerns. Allison Allison Arwady, MD, MPH Commissioner Chicago Department of Public Health (b)(6) H EALT HY C H IC A GO From: David Barr ------------ (b)(6) Date: Wednesday, April 22, 2020 8:47 AM Percak, Jeffrey M --:-:-:--:=====~~~-------Conrad, Patricia (NIH/NIAID) [El Demetre Daskalakis Mushatt, ======~~- >; Barasch, Kimberly (NIH/NIAID) [C] Preetha (DOH) Duchin, Jeff ....:..=========~~----------------To: Al lison Arwady (b)(6); Anthony (NIH/NIAID) [El (b)(6)>; Fauci, (b)(6)>; (b)(6)>; (b)(6)>; (b) (6)>; (b)( 6) David M Iyengar, (b)(6) (b)(6) Subject: Notes from call with Dr. Fauci Hello - Thank s for all for a very informa tive and sobering discussion last night. I've provided bullets below to capture the main points. Please add or change as needed. I've kept this relatively short but can supply a full recording of the call if you want it. We will have another call next Tuesday. David PPE supplies: - whi le hospitals are in better shape than a few weeks ago, significant shortages remain at longterm care facilitates , skilled nursing facilitates , outpatient settings like doctors' offices and urgent care clinics, shelters, prisons. Gowns are the biggest problem, but gloves, masks and shields are also short. Doctors offices are closing for lack of PPE. - each city is trying to solve these shortages in a short-term , piecemeal way. They need a longe rterm solution to stab ilize availability. Outpatient settings are looking to health departments to provide supplies , something HDs are not set up to do. - testing in most places still requires PPE use (e.g. no avai lability of anterior nasal swabs) and the PPE shortages are severely limiting testing scale up. - even at hospitals , supply limitations make re-opening elective surgerie s and other procedures impossible at this stage. - If considering re-opening businesses, this will drastically increase PPE needs to a whole new secto r. TESTING challenges: - Each city reported that, despite improvements, a very limited number of tests are being perfom1ed compared to need. - Supply shortages are the biggest challenge: swabs, PPE, sample kits, reagents are the biggest obstacles. Not clear where this is going to come from or who is responsible for addressing problems. - Private labs limit number of sample kits distributed each week . In places where public labs are available, there is a push to get providers to use the public labs. But many places don't have public labs. - There is no clear guidance on how to prioritize who gets tested first. So, in some places, that means that people at lower-risk are being testing but people at greater risk (due to symptoms , exposure , high-risk living /work environment, etc) are not being testing. Guidelines are needed to help prioritize where testing resources are used first. - Public testing produces skewed results . Testing becomes available only to those who can make an appointment and who can drive to the site. This means many lowerpriority people get tested but high-priority people do not. This skews understanding of positivity rates. - Some labs are underutilized - but the reason is that there are breakdowns in the supply chain that make it difficult to test people and get tests to the labs. (e.g .) (b) <4) - Reimbursement is an obstacle. CMS offering to cover test costs ($100 per test) would help get labs to do more testing. It would not solve the problem , but it would help. - Proliferation of unvalidated antibody tests is causing confusion. High rates of false results, misinterpretation of what results mean (e .g. telling people who test antibody positive that they must quarantine for two weeks). Ch icago spends a lot time shutting down these testing sites as they make things harder and use up supplies. - there is increasing pressure to reach a target nwnber of tests performed each day in order to get to 're-opening'. But the number needed is contextual based on the environment, population there isn't one 'right' number for everywhere. - Need better public messaging on difference between virology and serologic tests. - Current testing capacity is no where near what is needed to make informed decisions about reoperung. TESTING: reporting challenges - CwTent PoC tests have no link to provide results to health departments . Many outpatient facili ties and SNF s have no system for repo rting test results to HDs. Need electronic link for reporting PoC test results. - While aggregate positive tests may be reported, negative result'>are not. - Impossible to really understand population levels of infection because ( 1) number of tests perfom1ed is too low and (2) not testing the 'right' people - Every one is pushing for rapid scale up of an tibody tests, but we still don't know what the results of these tests mean and bow to apply them to policy development. - CDC and NIH will each coordinate sere-surveys. No details on CDC approach yet. NIH study is up. Still not clear how to use the results of these studies , but useful to collect data now and apply it as knowledg e grows. Locally-coordinate aero-surveys can be helpful but only if tests are highly validated . The Future: - How many tests should we being doing? How much PPB/testings /beds/staff will be needed in the coming year? Next winter, we will face dual flu and COVID outbreaks, without stable testing capacity, how will we differentiate between the two? - What are the plans for contact tracing? Who will recruit and train? Is there a federal p lan or guidelines for this? How will it be paid for? What do we do to effectively isolate those infected? This e-mail , and any attachments thereto , is intended only for use by the addressee(s) named herein and may contain legally privileged and/or confidential information . If you are not the intended recipient of this e-mail (or the person responsible for delivering this document to the intended recipient ), you are hereby notified that any dissemination, distribution, printing or copying of this e-mai l, and any attachment thereto, is strictly prohibited. If you have received this e-mail in error, please respond to the individual sending the message, and permanently delete the original and any copy of any e-mail and printout thereof. From: Date: To: Cc: (NIH/N IAID) [El Subject: study Fauci, Anthony (NIH/NIAID) [E) Thu, 23 Apr 2020 12:53:24 +0000 Stover, Kathy (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad, Patricia RE:FORASFREVIEW:Draft PRre: launch of hydroxychloroquine /azithromycin Looks fine. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Stover, Kathy (NIH/NIAID) [El (b)(6) Date: Wednesday, April 22, 2020 3:56 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Billet, Courtney (NIH/NIAID) [E) (b)( ·; Folkers, Greg (NIH/NIAID) [E) (b)(6)>; Conrad, Patricia {NIH/NIAID) [E) (b)(6) Subject: FORASFREVIEW:Draft PRre: launch of hydroxychloroquine/azithromycin study ------ --=-= ·'======~~ -------- Hi Dr. Fauci, Please find attached for your review a draft press rel ease describing the launc h of the ACTG hydroxychloroqu ine/azithromycin study for COVID-19. NIAID will issue the release after the first participant(s) has enrolled, which is currently anticipated around May 1. The following is the quote we have drafted for you: "We urgently need a safe and effective treat ment for COVID-19. Repurposing existing drugs is an attractive option because these medications have undergone extensive testing, allow ing t hem to move quickly into cli nical trials and accelerating thei r potential approval for COVID-19 t reatment ," said NIAID Director Anthony S. Fauci, M .D. "Although there is anecdota l evidence t hat hydroxychloroquine and azithromycin may bene f it peop le with COVID-19, we need solid data from a large random ized, control led clinical trial to determ ine whether this experimental t reatment is safe and can improve clinical outcomes. " Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch Nationa l Institute of Allergy and Infectious Diseases(NIAID) Office of Communications and Government Relat ions Nationa l Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mai Cb)(6) NIAID Med ia Line: (301) 402-1663 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Thu, 23 Apr 2020 11:54 :41 +0000 Corey MD, Larry (b)( ;Masco la, John (NIH/VRC) [E] Conrad, Patricia (NIH/NIA ID) [E);Fauci, Antho ny (N IH/NIA ID) [E] NEJM m anu script COVID vaccine editoria l_ prefinal April2 1_7pm fsc - w ith minor Fauci edits. docx Larry/John: I have gone over the changes that Francis has inserted and I have edited some of them. Please accept his changes and my edits of them (or any additional edits that you have) and then it is OK to send in . Please let me know if you have any questions. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 11:13 :29 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: seeking your advice on a COVID-19 question Email from Pardis Sabeti. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( (b)(6) From: Pardis Sabeti Se nt: Wednesday, April 22, 2020 9:47 PM To: Fauci, Anthony (NIH/NIAID) [E)--------=(b) :--: (6) => Cc: Collins, Francis (NIH/OD) [E] (b)(6) Subject: Re: seeking your advice on a COVID-19question ---------- ------- Awe, thank you, here for you two any time, and grateful for the enormous positive impact you have on the world, Pardis On Wed, Apr 22, 2020 at 9:43 PM Fauci, Anthony (NIH/NIAID) [E] Thanks, Pardis. ------- It was great to spend time with you and your colleagues. Warm regards, Tony From: Collins, Francis (NIH/OD) [E] ______ Cb> _C _6)> Date: Wednesday, April 22, 2020 8:44 PM To: Pardis Sabeti (b)(6)> (b)( > Cc: Fauci, Anthony (NIH/NIAID ) [El Subject: RE: seeking your advice on a COVID-19 question -------- Hey there Pardis, You are much too kind - but we are grateful for YOU and your team! It was fun to talk science for a litt le whi le. Q (b)(6)> wrote: We learned a lot. Best, Francis From: Pardis Sabeti (b)(6 )> Date: Wednesday, April 22, 2020 8:38 PM ------ To: Collins, Francis (NIH/OD ) [El Cc; Fauci, Antho ny (NIH/NIAID) [El ==> (b)( (b)(6)> Subject: Re: seeking your advice on a COVID-19 questio n Dear Francis and Tony, Thank you for a great conversation. Jacob, Bronwyn, and I stayed on a moment after you left and talked about how inspired we are by each of you and by the camaraderie between you two . Jacob added thos e two are national treasure s, and Bronwyn and I whol eheartedly agreed. Grateful for you both, Pardis On Wed, Apr 22, 2020 at 8:21 AM Collins, Francis (NIH/OD) [E] Hi Pardis, -------- (b)(6):> wrote: See attached paper that argues there may be a significant difference in virulence of the COVI0- 19 clade that predominates on the west coast compared to the east coast. Tony Fauci and I would like to kno (b) (5) Also attached is a MedRxiv preprint that describes major differences in pathogenicity of different viral st rains. I just got this (b)(5) Can I talk with you later today after yo u have a chance to review this? Thanks, Francis Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Healt h Broad Institute of MIT and Harvard Howard Hughes Medical Institute Assistant: Phone:_.!===~ (b)(6) (b~ H~----------- Website: www .sabeti lab .org Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard T.H. Chan School of Public Health Broad Institute of MIT and Harvard Howard Hughes M edical Institute ,...!:==~~:;:;;------------ CbH > Assistant Phone: (b)(6) Website : www.sabetilab.org ------ From: Date: (b)(6) Thu, 23 Apr 2020 07:09 :44 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: invitation to New Zealand conversation To: Subject: Sent from my iPhone Begin forwarded me ssag e: From: Pat Brittenden < info@blindfi sh.medi a> Date: April 23, 2020 at 12:02: 13 AM ED T ,------To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: invitation to New Zealand conversation -------- --;;-~ (b)( Good afternoon Dr Fauci, We are intere sted in seeing if you would be ava ilable for a chat via Zoom to New Zealand abou t COVID- 19 The US is an essential part of the NZ economy contr ibuting between $1.5 and $2 billion dollars annually from tourism alone and we would love to have a conversation about where the US is at, how COVID-19 is being dealt with, and the future of things that could lead up to opening our borde rs again. We're happy to have you for any length of time, but if you hav e 10-20 minutes that would be amazing. Thank you for what you are doing in thi s global event, I hope we can connect sometime soon Sincer ely, Pat Brittenden www. theDOC.nz www .patbrittenden.com /abou t (b)(6) From: Date: (b)(6) Thu, 23 Apr 2020 07:08:26 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h LeadersCall, Thursday, 23 April, 14:30 CET To: Subject: Sent from my iPhone Begin forwa rded me ssage: From: "KABIR, Sophia" (b)( > Date: April 23, 2020 at 6:54:46 AM EDT To: SHO C , Office of the Director-Genera l , "Redfie ld, Robert R. (CDC /OD) " (b) (6) (b)( (b)(6) "Felicity Harvey , "Chris.Elias" , (b)(6). , (b)(6) "Fauci, Anthony (NIH/NIAID) [E]'' "GREIN , Thomas" "COX , Paul Michael" -----"SCHWARTLANDER, Bernha rd F ." (b)( (b)(6)., , "MINHAS, Raman" "Conrad,Patricia (NIH/NIAID) [E]" --------. Jaouad" (b)( , "FALL, Ibrahima Soce" ----------. (b)(6) (bH6) >, "MAHJOUR , (b) (6), "Thomas (b)(6) (b)(6) , Preside nt I Resolve to Save L ives ,-------(b) (6), "Amadou.SAL L" (b)(6) "AL- (b)(6) SHORBAn, Farah" 1--c,~ Robynn Leidig "DRURY, Patric k Anthony" (bH · , (b) (6), "Dr VAN KER.KHO VE, Maria" (b)(6) ----------------- "GRAAFF , Pe ter Jan" CbH6), "POOLE , Marcia" Cb)(6) , Tarik Mohammed Cb)(6) Carlos ~ (b)(6) ~ , Ryan Morhard (b)(6) "BRIAND, Sylvie" CbH6) , "MORGAN, Oliv er' "Ha JTi es, Jenny" CbH , "Awwad, David (NIH/NIAID) [C]" CbH6) >, "SIMONSON, Stewart" CbH6) "SINGER , Peter Alexander" CbH , "Jayatunga , Wikum" Navarro Co lorado ------ -------- (b)(6) "Julie.HA LL" RIOUX , "SHIN, Young-Soo" "SMITH, Ian Michael" Raymond Bruce J." Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, BernhardF." ....____ _,, CbH6)"MAHJOUR, Jao uad" CbH , "FALL, Ibrahima Soce" CbH , "GREIN, Thoma s" CbH6J >, "MINHAS , Raman" CbH6) , "COX, Paul Michael" ____ CbH6J, "AL-SHORBAJI, Farah" CbH >, "POOLE , Marcia" CbH6l , "DRURY, Patrick Anthony" CbH · , "GRAAFF, Peter Jan" CbH6J, "Dr VAN KERKHOVE , Maria" Cb> <6J, "FARES, Christine Youssef' ------ (b)(6) Subject: RE: Global Health Leaders Call, Thursday, 23 April, 14:30 CET Dear colleagues, Apologies for the mistake in the below subject line. The meeting starts at 14.30 CET, as mentioned in the email. Kind regards, Sophia From: KABIR, Sophia Date: Thursday, April 23, 2020 10:51 AM To: SHOC ; Office of the Director -General ; (b)(6) (b)(6) , "'.'--~==::!.....::..__ _____ , TLANDER , Be .:_ ___ rd F. ..!::::======~ (b)(6); (b::-= )( ~6);- MINHAS, MAHJOUR,Jaouad (b)(6); FALL,lbrahima Soce :..--.....:=======::;..,:-:-=(b)( ; 'Elhadj SY' ; 'Thomas R. Frieden' (b)(6); 'Lynn Banks' (b)( ·; 'President I ======"=~ -------- (b)( 6) AL- n Leidig' (b)( ·; DRURY, ~-:-::-:-:::--:-:---:--;::::=====:::,;...--,;-s-= r VAN KERKHOVE,Maria (b)( 6) (b)(6) SMITH, Ian Michael (b)( Cc: SHOC; Office of the Director-Gen eral ; SCHWARTLANDER,Bernhard F. (b)(6) ; MAHJOUR, Jaouad (b)(6)r>; FALL, lbrahima Soce (b)(6); GREIN,Thomas (b)(6J'c> ; MINHAS, Raman (b)(6); COX, Paul M ichael (b)(6); Al -SHORBAJI, Farah (b)( ; POOLE,Marcia (b)(6) >; DRURY,Patrick Anthony (b)(6)·> ; GRAAFF,Peter Jan _____ (b _J~(6) ~;_Dr VAN KERKHOVE,Maria _______ (b _~_<_.·>; FARES, Christine Youssef (b)(6) Subject: Global Health leaders Call, Thursday, 23 April, 14:00 CET ====~~- ::::::=====~-= ====~~ ::::::=====~~ -----===~~~ Dear colleagues, Ahead of the Global Health leaders Call at 14.30 CETtoday, please find an epidemiological update and analysis attached , in addition to the "Consideration s in adjusting public health and social measures in t he context of COVID-19" inte rim guidance document, which was publ ished on the WHO website on 16 April. Please find below, t he key questions for your consideration and input. 1. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rtant? 3 . What should be the priorit ies for the 1-2 weeks? 4. Any other issues you see as important? You will be able to connect via t he Webex connection below. If you experience any technical difficulties, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 or via email: shoc@who.int. Best, Sophia Meeting number (access code): Meeting password (b) (6), (b) (4) ------ (b)(6),(b)(4) ------- Thursday , April 23, 2020 2:00 pm I (UTC+02:00) Brussels , Copenhagen, Madrid, Paris Join meeting Join by phone Tap to call in from a mobile device (attendees only) (bH6JTZERLAND Toll SToll Global call-in numbers From: Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 02: 16:12 +0000 Alice Park FW: Time follow up MedRxiv_ Mutat ions impact pathogenicity SARS-CoV-2_ Lanj uan Li et al. 2020 .04.14 ..pdf Alice: Here is anot her manuscript. Tony From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu,23 Apr 2020 02:11:27 +0000 Lou lgnarro RE:Greeti ngs- NOT urgent Lou: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards, Tony From: Lou lgnarro (b)( sent: Tuesday, April 21, 2020 5:38 PM To: Fauci, Anthony (NIH/NIAID) [E] -------= Subject: Gr eet ings- NOT urgent (b,.,.. )(=6) Hi Tony, This is Lou lgnarro from UCLA. You and I shared the stage in the "Shoe" at the Ohio State University a few years ago, where you gave the Graduation Address to the undergraduate seniors . I was on stage with you, to receive an award for my basic biomedical research which resulted in my being awarded the Nobel Prize in Medicine in 1998. I recall the nice conversations we were enjoying with Sanjay Gupta while robing for the event. Thanks for the tru ly spectacular job you are doing, regarding the coronavirus pandemic. We Nobel Laureates especially regard your work as the most important during our lifetime. Thank you and God bless. My best wishes, Lou lgnarro From: Fauci, Anthony (NIH/NIAID) [E] Thu, 23 Apr 2020 01:50:03 +0000 Conrad, Patricia (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] FW: letter from the Governor of Puerto Rico Dr. Anthony S. Fauci, MD[2].pdf Date: To: Cc: Subject: Attachments: Heads up for a call from the Puerto Rican Health Minister. From: Pablo L. Pena Antonmarch i Date: Wednesday, April 22, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b =)""'(6) => Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6):>; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6J>; Jennifer M. Storipan ; Juan L. Negron ; Maria del C Reyes Crespo ; Antonio L. Pabon Batlle Subject: letter from the Governor of Puerto Rico Importance: High ---------- Dear Dr. Anthony Fauci: I am sending yo u for you r attention a letter from the Governor of Puerto Rico Hon. Wanda Vazquez Garced. Cordially, Pablo L. Pena Antonmar chi Executive Assistant Ledo . Antonio Pabon Batlle Chief of Staff Office La Fortaleza . * ., LA PORTALEZA NOTA DE CONFIDENCIALIDAD:Esta transmisi6n electr6nica cont iene informaci6n perteneciente a la Oficina del Gobernado r, que es confidencial, privilegiada y/o privada bajo las leyes aplicables. Solamente podra ser util izada par la persona o entidad a la cual se dirige. Si usted no es el destinatario intencional, se le notifica que se prohibe cualquier uso, disem inaci6n o copia de esta comunicaci6n. Si usted recibe esta comunicaci6n por erro r, favor de notificar al remit ente y eliminar este correo electr6nico de su sistema. CONFIDENTIALITYNOTE: This electronic transmission contains information belonging to the Governor's Office, which is confidential , privileged and exempt from disclosure under the applicable law. It is intended solely for the use of the individual or entity to which it is addressed. If you are not the intended recipient, you are hereby notified that any use, dissemination, or copying of the communication is strictly prohibited. If you have received this communication by error, please notify the sender and delete this e-mail from your system. From: Date: To: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Thu, 23 Apr 2020 01:40:52 +0000 Alice Park;Conrad, Patricia {NIH/NIAID) [El RE:Time follow up Viral Clades Brufsky 42020 Accepted Final.pdf Alice: It was great working w ith you today. Here is the reference. I believe that it will be in the Journa l of M ed ical Virology . It has been accepted, but is no yet in print. Best regards, To ny From: Alice Park Date: Wednesday, April 22, 2020 6:30 PM To: Fauci, Anthony (NIH/NIAID) [El ;Conrad, Patricia {NIH/NIAID) [El Subject: Time follow up Dear Dr. Fauci -- many thanks for your time today; we are thrilled to have you as part of the TIME 100 Talks, which will go live tomorrow. In the meantime, I wanted to double check the reference to the study you mentioned about the east and west coast strains and their potentia l difference in virulence. Realize it's preliminary, so just wanted t o confirm any references we make to it. I checked the biorxiv and medrx iv but didn't find the citation. Would appreciate the journal if it was pub lished . Many thanks! Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny From: Date: To: Cc: Subject: Attachment s: Fauci, Anthony (NIH/N IAID) [El Wed, 22 Apr 2020 16:29:19 +0000 -----~~ Collins, Francis (NIH/OD) [El Corey MD, Larry (b)(6) CbH6lMascola, John (NIH/VRC) [El FW : "final draft" COVID vaccine editorial _ prefinal April21_7pm.docx Francis: Here is t he paper th at I mention ed to you and t hat w e are plannin g to submit to the NEJM. I have put you r name on it as the senior author. If you are comfort able wit h th at , we will go wit h it. Please tak e a look at th e manu scrip t and make any comment s or edits t hat you see fit. Thanks, Tony Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:09 +0000 Billet, Courtney (NIH/N IAID) [E] Greg Folkers (b)( 6) ;Conrad, Patricia (NIH/NIAID) [El RE:Request for Dr. Fauci + Ryan Zimm erman Pros For Heroes I COVID-19 Relief From: Date: To: Cc: Subject: Fund I w as t hinking t he very same t hing. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Billet, Courtn ey (NIH/NIAID) [E) Date: Tuesday, April 21, 2020 8:43 PM To: Fauci, Anthony (NIH/NIA ID) [El Cc: Conrad , Patr icia (NIH/NIAID) [E] ------ (b)(6) (b)(6) > ::;..,..-,= (b)(6)> ~======~ = >; Folkers, Greg (NIH/NIAID) [E] ---------(b)( Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Ps - what do you want to bet you get invited to throw a first pitch next year? From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:38 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Cc: Conrad, Patricia (NIH/NIAID) [E) """' (b..,.. ~= c6)> (b)(6) •> ; Folkers, Greg (NIH/NIAID) [E) (b)(6)> Subject: FW: Request for Dr. Fauci+ Ryan Zimmerm an Pros For Heroes We're a "go" on this . I'll circle back with his rep tomorrow. I COVID-19 R@lief Fund On Apr 21, 2020, at 6:50 PM, Billet , Courtney (NIH/NIAID) [E] w rote : -------- (b) (6) > Hi guys - as a huge Nats fan, Dr. Fauci very much wants to do this chat with Ryan Zimmerman. Can I get a green light to work on this with them? I'll get the q's but it will be the same general theme as with Steph Curry, YESNetwork, etc. From: Judee Ann Williams Se nt: Tuesday, April 21, 2020 5:54 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E] --------=-s-= (b)(6) Subject: Re: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes Fund I COVID-19 Relief Absolute ly! We would 100% be able to work aro und that and avoid any association of fund raising. We wou ld set this up however he will be most comfo rtab le, seed questions in advance, etc. and shed a light on what is most helpfu l. Will wait to hear and if you need anything else ju st let us know . Thank yo u so much ! From: "Billet, Courtney (NIH/NIAID) [E]" Date: Tuesday, Apr il 21, 2020 at 4:41 PM --------- To: Judee Williams Cc: Christine Lancman , (b)(6) "Routh, Jennifer (NIH/NIA ID) [E]" (b)(6) Subject: RE:Request for Dr. Fauci + Ryan Zimmerman Pros For Heroes Relief Fund I*Exte rnal Send er* I COVID-19 Hi - thanks for your message - we will check and someone will get back to you in the next few days. One caveat is that as a Federal official, Dr. Fauci cannot be associated with fundraising in any way . Please confirm that is someth ing you would be able to work around? From: Judee Ann Williams Date: Monday, Apri l 20, 2020 5:21 PM To: Routh, Jennifer {NIH/ NIAID) [E] (b)(6)>; Billet, Courtney (NIH/N IAID) [E] (b)( > Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennife r & Courtney Hello! Our fr iends fr om Ste ph Curry's team passed along your contact info rmat ion t o us and we work at CAA whe re we represent Wor ld Series Champion, Ryan Zimmerman. Ryan wanted to exp ress his grat itude first & fo remost to Dr. Fauci, the ent ire te am and all thos e beh ind th e scenes working arou nd the clock. Ryan recent ly launc hed the Pros for Heroes Covid-1 9 Fund last week, w ith more tha n 30 pro fessional athle tes suppo rting and over $300,000 raised across 1,400 separate dona t ions. (>www .prosforhe roes.org<). Since its launch last Tuesday, contribut ions from the Pros For Heroes Fund have go ne directly :awards PPE needs throug hout th e Inova hospita l netw ork t hroug hout the m id-Atlantic and have helped provide meals t o those cr it ical care fron t -line workers - keeping these front -line heroes covered at work and comfortable at home . If Dr. Fauci was up to it, Ryan would love to host eithe r a short 15 minute Q&A on his Facebook to continue raising awareness for how we need to be respon ding to the ongoing crisis. Or even simply thank Dr. Fauci for the tire less work he is doing and shine a light on how fo lks can support these critical fron t line workers. We are also open to what you th ink w ould work best ! Wou ld there any openings that w ould work best? We know Dr. Fauci is big baseball fan, and of course we are all huge fans of his! If we can ever be support ive or help navigat e anything in the wo rld of pop cultur e, please do not hesitate t o ask. Warm est w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 2 12-277 -5294 I M: (b)(6) I Washington, DC NEW YORK - LONDON -NASHVILLE-M UNICH - LOSANGELES-BEIJING - SHANGHAI >https://www .caa.com/< Pros For Heroes "Teamwork is th e ability t o come t ogeth er tow ards a common goal. We are looking forward t o at tra cting as many supporters t o help join this cause and give back as much as we can to tho se who have given us so much," said Washington Nationa l All-Star, Ryan Zimmerman, th e fu nd's fo under. Social Links: >https://www.instagram.com / prosforheroes/< >http s://twitter.com/prosforheroes< Today Show: >https://www.today.com/video/ryan-zimmerman-talks-pros-for hea lth-care-wor ke rs-82 2026935 77< -heroes-fund -for -feeding- Washington Post Launch Article: >https://www.washingtonpost .com/sports/2020 / 04/ 14/nationals-ryan-zimmerman-startsfund-hea Ith-care-workers -with- lO0k-gift/ < This e-mail and any files transmitted with it are intended solely for the use of the individual or entity to whom they are addressed. 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If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited. CAA is committed to ensuring that clients are free to do their best work without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to >https://www .caa.com/legal/sexualharassment-guidelines-caa-clients< to learn more about their rights, and how to report violations. From: Fauci, Anthony (NIH/N IA ID) [El Date: Wed, 22 Apr 2020 00:29:33 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Subject: FW: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations aff ect dead liness of strains, Chinese study finds ------- More on mutations From: Fauci, Anthony (NIH/NIAID) [E] Sen t: Tuesday, April 21, 2020 1:58 PM To: Graham, Barney (NIH/VRC) [E)------=(b=H=6) Subject: FW: SCMP: Coronavirus's abi lity to mutate has been vast ly underestimated, and mutat ions affect deadli ness of strains, Chinese study finds Not peer reviewed, but w hat do yo u t hink? Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg {NIH/NIAID) [E] (b)( > Date: Monday , Apri l 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vast ly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The most aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier stra in imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic . Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the wor ld . Professor Li Lanjuan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported. These muta tions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity, " Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the first hard evidence that mutation could affect how severely t he virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation. She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predominant varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse. But the weaker mutation did not mean a lower risk for everybody, according to Li's study. In Zheji ang, two pat ients in their 30s and 50s who contracted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit. This finding could shed light on differences in regiona l mortality. The pandemic's infection and death rates vary from one country to another, and many explanations have been proposed. Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof . The issue was further complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type. In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the stra in they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development , while urgent, need to take the impact of these accumulating mutations ... into account to avo id potential pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown ,accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually invo lved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new. They found some of these mutations could lead to functional changes in the v irus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity. To verify the theory, Li and colleagues infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also kil led the cells the fastest. It was an unexpected result from fewer than a dozen patients, " indicating t hat the t rue diversity of the viral strains is still largely underapprecia ted," Li wrote in the paper. -Professor Li Lanj uan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuha n, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month . By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach t hat could generate a result quickly . The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been over loo ked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient , which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper . Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Informat ion Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful information," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectable symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Fauci, Anthony (NIH/NIAID) [El Date: Wed, 22 Apr 2020 00:16:44 +0000 -----~~ To: Collins, Francis (NIH/OD) [El (b)(6) Subject: FW: For your attent ion Attachments : COVAX2020-A GLOBALEFFORTfor the ACCELERATED DEVELOPMENT, PRODUCTIONand EQUITABLEACCESSto COVID-19 VACCINES_16Apr2020_0RAFT.docx ------- See attachment (b)(5) that Hilary sent me. ________ _, (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Tuesday, April 21, 2020 7:44 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: For your attent ion (b)(6) (b) (5) From: Anthony Fauc i Cb)<> Date: Tue sday, April 21, 2020 at 7:30 PM To: Hila ry Marston (b)( v> Subject: FW: For your attention Have you heard of this on any of the calls where you represent me?? From: Collins, Francis (NIH/OD) (El (b)(6) Date: Tuesday, April 21, 2020 7:28 PM To: Fauci, Anthony (NIH/ NIAID) (El--------=- (b""" )(= ; Lane, Cliff (NIH/N IAID) (El Tabak, Lawrence (NIH/OD) (El (b)(6)>; Freire, Maria (FNIH) (Tl ; Wholley, David (FNIH) (T) Subject: FW: For your attention -------- (b)( ·; Hi all, See note below from Victor Dzau about a g loba l effort on COVID-19. I can't tell if this is more than a fund-raising effort. I know we have Gates reps on our ACTIV working groups- this p lan come up , David ? Francis From: Dzau, Victor J. Date: Tuesday, April 21, 2020 4:10 PM To: Collins, Francis (NIH/OD) [El ------=Cc: Kanarek, Morgan Subject: For your attenti on (b'""' )( =6) has any of Dear Francis, Congratulat ions on your launch of Public Private Partnership to speed COVID 19 vaccine and treatment options. This is very timely and much needed. Kudos to your leadership . I am sure you are aware of a global coordinating effort to accelerate vaccines, diagnostics and therapeutics. I have been part of the conversation and planning along with Jeremy Farrar, Richard Hatchett , Seth Berkley, Chris Elias, Paul Stoffels etc . Recently WHO, Gates Foundation and European Commission have been leading the planning. This has advanced rapidly and is in the final stages in development that wil l be soon announced. It has involved European Commission, Germany, Japan, UK, Norway , France, Saudi as well as Gates Foundation, WHO, World Bank, Wellcome Trust, GAVI, Global Fund, CEPI,GPMB and private sector industry . The initiative will begin with a Pledge conference for $8B as a starting point. This will be led by President van der Leyen and is co-chaired by the above country leaders. This will occur on M ay 4 . In addition by the end of this week or early next week there will be an announcement on the global coordinating structure with w ill involve Gates, WHO etc . I am writing to be sure that you and the White House are aware of these upcoming events . Can you share this information with the White House? Besides you, who else should I share this information with? I will be happy to send you background documents if you wish . Please call me anytime. Best, Victor From: Date: To: Eisinger, Robert (NIH/ NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 21 Apr 2020 23:10:36 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Consideration of IM COVID Immune Globul in for Prevent ion of COV ID-19 Subject: Infect io n Attachment s: Prophylact ic Intramuscular COVID- IG - Oxman.pdf, FURTHERARGUM ENTS IN FAVOROF INTRAMUSCULARCOVID-IGVersion 4 - Oxman.pdf Email from Gary Noble, advisor to Bob W indom in the 1980s. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Off ice of the Director National Institute of Allergy and Infectious Diseases Nat ional Institutes of Health 31 Center Drive, Room 7A-03 Bethesda M D 20892 Telephone: (b)(6) Email : (b)( From: Gary Noble (b)(6) Date: Tuesday, Apr il 21, 2020 4 :56 PM To: Fauci, Ant hony (NIH/ NIAID) [E] (b)(6)> Cc: M cGowan, John J. (NIH/ NIAID) [E] (b) (6); Conrad, Patricia (NIH/ NIAID) [E] (b)(6J·; Oxman, M ichael (b)( · Subject: Consideration of IM COVID Immune Globulin for Prevention of COVID-19 Infection -----~= -------- Dear Tony, I will always remember our amazing collaboration during the HIV/AIDS days in the 1980s , when I served as AIDS Advisor to Bob Windom , the DHHS Assistant Secretary for Health during President Reagan's administration. And now, I am delighted and amazed to wat ch you so adroitly maneuver the COVID-19 scientifi c policies and keep them front and center in the current White House!! Cb><6>\, Michael Oxman, has worked ---------------with John Zaia at City of Hope , and a Mayo/ Hopkins /Michigan State consortium for a tria l of IM COVID-IG as a prefe rred method for treatment and prevent ion of COVID-19. This week , Mike expects to complete the protocol for a placebo (normal IG)-controlled trial of IM COVID-IG prophylaxis in at-risk healthcare workers who are engaged in direct patient care at UCSD, but they need a modicum of support. Mike asked if I would reach out to see if NIAID might provide of support for this effort, using IM, as opposed to IV, COVID-IG. I've copied Mike, who has provided the attached background information. Tony , with all my respect and admiration for what you are doing for the U.S. and for all of us. Gary Gary R. Noble, MD, MPH, MA (Oxon) From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 22:14:24 +0000 NIAIDODAM FW: Invitation to Speak at UC Berkeley COVID-19 Hackathon Date: To: Subject: Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Saahil Chadha Date: Tuesday, April 21, 2020 11:00 AM _, To: Fauci, Anthony (NIH/NIAID) [E] CbH6)> Subject: Inv itation to Speak at UC Berkeley COVID-19 Hackathon ------~~ _______ Dear Dr Fauci, My name is Saahil , and I'm a director at Cal Hacks , a student organization at the University of California, Berkeley. This upcoming weekend, we will be hostingh ack:now , a 36-hour global online hackathon to foster innovative and technical solutions to tackle the challenges faced around the current COVI D-19 pandemic. We're projected to have 1,500 participants from around the world. I'm reach ing out to invite you to be our opening ceremony speaker. Specifically , this Friday night, April 24 , from 7-8pm Pacific Daylight Time , we're going to be hosting the opening ceremony of our event. At this time , we want to inspire our hackers to help solve global challenges relate d to health and community. We would be absolutely honored if you would join us to speak at our opening ceremony for just a few minutes to share your experiences with and response to the COVID-19 pandemic. Your unique perspective and expanse of knowledge makes you the most qualified person, and we would be humbled to include you as our opening ceremony speaker. Please let us know if you are able to accept this invitation. Stay safe , Saahil Chadha (b)(6) Calhacks .io From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 2020 22:06:57 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El RE: Message for Dr Anthony FAUCI OK. Please take care of this. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Folkers, Greg (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:31 AM To: Conrad, Patricia (NIH/NIAID) [El --------,;(b)(6) (b)(6) (b"'"'"' )(=6):>; Fauci, Anthony (NIH/NIAID ) [El Subject: RE: Message for Dr Anthony FAUCI I wou ld be extreme ly grateful to you if you can provide me with the most recent and pertinen t scientific and population data concerning cov id-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b)(6)_ Not exactly sure what he wan ts but I can send him some links that will get him the latest CoV info from pubmed, prepr ints, CDCetc From: Conrad , Patricia (NIH/NIAID) [El Date: Tuesday, April 21, 2020 11:16 Atvl To: Fauci, Anthony (NIH/NIAID) [E]-------= Cc: Folkers, Greg {NIH/NIAID) [El _______ Subject: FW: Message for Dr Antho ny FAUCI Can we direct her somewhere? Gray? (b)(6)> (b) ""' (= 6)> CbJ _C6) _ Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAIO by one of its representatives . ------------------ From: Jean-Louis Touraine Date: Tuesday, April 21, 2020 11:06 AM To: Conrad, Patricia (NIH/NIAID) [E]________ (b)( > (b "")'""' (6) = Subject: Potential SPAM:Message for Dr Anthony FAUCI I wou ld be very grateful to you if you can forward the following mail to Dr Anthony FAUCI. Many thanks. Sincerely yours, Pr Jean-Louis TOURAINE,Lyon and Paris, France. Dear Tony, You may remember, that we have met repeatedly and worked in parallel and in association, during the early years of the HIV epidemic . You and I have been trained in immunoly. Both of us are much sollicitated to help facing and f ighting the covid-19 epidemic . During the past years, as well as recently, I have followed with great interest and respect your accomplishments and your advices in the fights against epidemics. I would be extremely grateful to you if you can provide me with the most recent and pertinent scientific and population data concerning covid-19. I know how extremely busy you are but maybe a collaborator of yours whether he can send me the data via e-mail (b) (6) This will allow me to give more documented informations to the French President and Government. Cooperation between countries will be crucial against covid-19 as it has been against HIV and other agents. I look forward to seeing you again in quieter times. Many thanks and very best personal regards. Jean-Louis TOURAINE, M.D., Ph. D., M.P. Ce message, ainsi que les pieces jointes, sont etablis, sous la seule responsabilite de l'expediteur, a !'intention exclusive de ses destinataires ; ils peuvent contenir des informations confidentielles . Toute publication, utilisation ou diffusion doit etre autorisee prealablement. Ce message a fait l'objet d'un traitement anti-virus. 11est rappele que tout message electronique est susceptible d'alteration au cours de son acheminement sm Internet. Yous pouvez consulter le site de l'Assemblee nationale l'adresse suivante : http://www.assemblee-nationale.fr a From: Fauci, Anthony (NIH/N IA ID) [El Date: Tue, 21 Apr 2020 21:39:30 +0000 -----~~ To: Colli ns, Francis (NIH/OD) [El (b)(6) Cc: Myles, Renate (NIH/OD) [E);Burk low , John (NIH/ OD) [E);Billet, Courtney (NIH/N IAID) [E);Conrad, Patricia (NIH/ NIAID) [E] Subject: FW: STAT: Director of U.S. agency key to hel ming vaccine deve lopme nt leaves ro le suddenly amid coro naviru s pandemic https://bi t. ly/ 2XRZqKa (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6) > From: Folkers, Greg (NIH/N IAID) [E) Date: Tuesday, April 21, 2020 3:01 PM Subject: STAT: Director of U.S. agency key to helmi ng vaccine deve lopment leaves role sudde nly am id coro naviru s pandemic ht t ps:// bit .ly/2XRZqKa -------- Director of U.S. agency key to helming vaccine development leaves role suddenly amid coronavirus pandemic By Nicholas Florko @NicholasFlo rko April 21, 2020 Rick Bright HHS WASHINGTON - Rick Bright, one of the nation's leading vaccine development experts and the director of the Biomedical Advanced Research and Development Authori ty, is no longer leading the organization, officials to ld STAT. The shakeup at the agency, known as BARDA,couldn't come at a more inopportune time for the office, which invests in drugs, devices, and other technologies that help address infectious disease out breaks and which has been at t he center of the government's coronaviru s pandemic response. Bright, whose departure was confirmed by th ree industry sources and two current Trump admin istration sources, will instead move into a narrower role at the National Institutes of Health overseeing a similar but lim ited public-pr ivate part nership aimed at vaccine development. Gary Disbrow, Bright's former deputy at BARDA,wi ll serve as the acting director of the office, an HHSspokesperson confirmed to STAT. BARDAwas expected to play an even larger role in the coming months; Congress more than tripled BARDA's budget in the most recent coronavirus stimulus package. Already, the office has a role in some of the splashiest Covid-19 projects, including partnerships with Johnson & Johnson and Moderna Therapeut ics, both of which are developing potent ial Covid-19 treatments . Related: This tiny federal agency was built to respond to a crisis like coronavirus. Now that it's here, is BARDA ready? BARDA has been plagued with management issues virtually since its creation in 2006, with much of the criticism aimed at a contracting department that some say is unresponsive to industry partners. The office has only had two permanent directo rs since its creation in 2006. Bright has led the organization since 2016. None of the sources articu lated the reason for Bright's departure, though several mentioned recent chafing between Bright and Bob Kadlec, the HHSAssistant Secretary for Preparedness and Response, which has oversight over BARDA. An HHSspokesperson confirmed that Bright will work on a recently announced NIH public-private partnership with 16 drug makers aimed at develop ing vaccines and treatments for Covid-19. "Dr. Rick Bright will transfer the skills he has applied as Director of the [BARDA)to the [NIH) .... Dr. Bright brings extensive experience and expertise in facilitating powerful pub lic-private partnerships tha t advance the health and well -being of the American people," the spokesperson said. Bright did not immed iately respond to requests for comment. Bright's career has largely centered around vaccine and drug development . His work at the Centers for Disease Control and Prevention focused on influenza viruses, antiviral drugs and tests . He has also worked in the biotechnology industry and served as an advisor to the World Health Organization. Before becoming BARDAdirector, he led the agency's Influenza and Emerging Infectious Diseases Division. Lev Facher contributed reporting. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NlAID , NlH , HHS, or the U.S. government. From: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 21 :18:24 +0000 To: Crawford , Chase (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E); McGowan , John 1. (NIH/NIAID) [ E];Ha rper, Jill (NIH/NIAID) [E];Gilles, Sharon (NIH/NIAID) [E);Lane, Cliff (NIH/NIAID) [E];John son, Martin S. (NIH/NIAID) [ E);Marston, Hil ary (NIH/NIA ID) [E];Bill et, Courtney (NIH/NIAID) [E] Cc: Haskins, Melinda (N IH/NIAID) [E];Selgrade , Sara (NIH/NIAID) [E) Subject: RE: Atte ntion: COVID-19 legislative package bill text released Date: Thanks. Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawfo rd, Chase (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [E) --------- (b)(6)> -------,;; CbH = >; Auchi ncloss, Hugh (NIH/NIAID) [E) (b)(6J> ; McGowan, John J. (NIH/NIAID) [E] "':"':"".".'.""."".~======--.J i':":"' 11":"'.' ( N"."'.' l'.""." H/":"'.' N':":"' IA "."". l~D:-: ) [~E:-:: ] ==~~--= (b=H~ >; Gill es, Sharon (NI H/N JAi D) [ E] = >; """-:--:-:--:-:::====:::::::......:..._~ Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Johnson, Martin S. (N IH/NIAID) [E] __;__ __;__,;___..;..:,~'=i-':-:----:-::-:--::-:-:" . (b)( ; Marston, H ilary (NIH/NIAID) [El (b)( -C-o -ur-tn_e_y'"'.' (_ N_ IH'"'.' / _N_IA-ID -:-)'"'.' [--: El~!,;._--....,;_ _ _;,(b,.:) ~(6) _ Cc: Haskins, Melinda (NIH~/ "."'. N-:-: IA-:-: 1D ~):-:[~E:-:: l ====--- ; Bille t, (b '""' )"'~= 6); Selgrade , Sara (NIH/NIAID) [El (b)(6) Subject: Atte ntion: COVID-19 legislative package bill text released Importance: High Good Afternoon, At 4p.m. today (4/21), the U.S. Senate is expected to hold a vote by unanimous consent on the "Paycheck Protection Program and Health Care Enhancement Act" (bill text attached). In particular please note that the legislat ive package includes the following supplemental appropriations for diagnostic testing (pages 13-15 of attached) : • NIH/OD - not less than $1B to develop, validate, improve, and implement testing and associated technologies; to accelerate research, development, and implementation of point of care and other rapid testing; and for partnerships with governmental and non-governmental entities to research, develop, and implement the activities outlined in this proviso. • funds in the preceding proviso may be transferred to the accounts of the Institutes and Centers of the National Institutes of Health for the purposes specified in the preceding proviso • the transfer authority provided in the preceding proviso is in addition to all other transfer authority available to the NIH • NCI - not less than $306M to develop , validate, improve, and implement serological testing and associated technologies for the purposes specified under this paragraph in this Act: • NIBIB - not less than $S00M to accelerate research, development, and implementation of point of care and other rapid testing related to coronavirus: • CDC - not less than $1B for surveillance, epidemiology, laboratory capacity expansion, contact tracing, public health data surveillance and analytics infrastructure modernization, disseminating information about testing, and workforce support necessary to expand and improve COVID-19 testing • BARDA- not less than $1B for necessary expenses of advanced research, development, manufacturing , production , and purchase of diagnostic , serologic, or other COVID-19 tests or related supplies, and other activities related to COVID-19 testing at the discretion of the Secretary • FDA-$22M to support activities associated with diagnostic, serological, antigen, and other tests, and related administrative activities We will keep you updated on any developments related to this legislation. Please let us know if you have any questions. Thanks, Chase From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 21:01:27 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Ryan Zimmerman (b)(5)- PC If cleared, I would love to. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Tuesday, April 21, 2020 4:43 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6l>;Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b)( ·; Folkers, Greg "'.'"' (N --1-H/-:N--IA--ID ~)-:-[E ::":' ]=====:!.;___...;._ =(b= )(6) ~ ------ == Subject: Ryan Zimmerman Would you be interested in do ing something with Ryan Zimmerman? Format TBD. We' ll pursue further discussion if you give the green light. From: Billet, Courtne y (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 4:41 PM To: Judee Ann Wi lliams Cc: Christine Lancman ; Routh, Jennifer (NIH/NIAID) [E) (b)(6) Subject: RE: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Hi - thanks for your message - we will check and someone w ill get back to you in the next few days. One caveat is that as a Federal official , Dr. Fauci cannot be associated with fundrais ing in any way . Please confirm that is something you would be able to work around? From: Judee Ann Williams Date: Monday , April 20, 2020 5:21 PM To: Routh, Jennifer (NIH/NIAID) [E] -------~~ (b)(6); Billet, Courtney (NIH/NIAID) [E] (b)(6)> Cc: Christine Lancman Subject: Request for Dr. Fauci+ Ryan Zimmerman Pros For Heroes I COVID-19 Relief Fund Jennifer & Courtney Hello ! Our friends from Steph Curry's team passed along you r contact info rmation to us and we work at CAA where we represe nt Wor ld Series Champion, Ryan Zimmerman . Ryan wa nt ed to express his gratitud e first & fo remost t o Dr. Fauci, the entire team and all those behind the scenes wo rkin g around the clock. Ryan recent ly launched the Pros for Heroes Covid-19 Fund last week, with more than 30 pro fessiona l athletes supporting and over $300,000 raised across 1,400 separate donat ions. (www.prosforheroes.org). Since its launch last Tuesday, contributions from the Pros For Heroes Fund have gone direct ly towards PPEneeds throug hout the Inova hospital netwo rk throug hout the mid Atlantic and have helped provide mea ls t o those critical care front -line wo rkers - keepi ng these front -line heroes covered at wor k and comfo rtab eat home. If Or. Fauci was up to it, Ryan would love to host eit her a short 15 minute Q&A on his Facebook t o continue raising awareness for how we need to be responding to th e ongo ing crisis. Or even sim ply t hank Dr. Fauci for the tir eless work he is doirg and shine a light on how folks can support th ese cr it ical fro ntline workers. We are also open to what you think would wo rk best I Would there any ope nings that would work best? We know Dr. Fauci is big baseball fa n, and of course we are all huge fans of his! If we can ever be support ive or help navigate anyth ing in the world of pop culture, please do not hesitate to ask. Warmes t w ishes, Judee Ann Judee Ann Williams I Co-Head, CAASocial Impact T: 212-277-5294 I M (b)(6) I Washington, DC NEW YORK· LONDON -NASHVILLE·MUNICH - LOSANGELES-BEIJING · SHANGHAI https://www.caa.com/ Pros For Heroes "Teamwork is the ability t o come together towards a common goal. We are looking forward to attracting as many supporters to help join this cause and give back as much as we can t o those who have given us so much," said Washington National All-Star, Ryan Zimm erman, the fund's founder. Social Links: https://www.instagram.com/prosforheroes/ https ://twitter. com/prosforheroes Today Show: https://www.today .com/video/ryan-zimmerman-talks -pros-for -heroes-fund -for-feeding -health-careworkers-82202693577 Washington Post Launch Article: https ://www. wash i ngton post. com/sports/2020/04/14/nationa care-workers-with- lO0k-gift/ ls-ryan-zi mmerma n-sta rts-fund-hea Ith- This e-mail and any files transmitted with it are intended solely for the use of the individua l or entity to whom they are addressed. If the reader of this e-mail is not the intended recipient or the employee or agent responsible for delivering the message t o the intended recipient, you are hereby not ified that any use dissemination, forwarding, printing or copying of this e-mail is strictly prohibited . CAA is committed t o ensuring that clients are free to do their best wo rk without experiencing harassment and want to ensure they have the relevant resources they need. Clients can go to https://www.caa.com/legal/sexua lharassment-guidelines-caa -clients to learn more about their rights, and how to report violations . From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:44:40 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Court ney (NIH/NIA ID) [E);clane@niaid .nih .gov RE:urgent: CNN request Cliff should do thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E) Se nt : Tuesday, April 21, 2020 4:41 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Fwd: urge nt: CNN request --------- -------~= --------- (b) (6):> (b)(6) Sent from my iPhone Begin forwarded message: --------- From: "Conrad, Patricia (NIH/NIAID) [E]" Dat e: April 21, 2020 at 4:31 :46 PM EDT To: "Billet , Courtney (NIH/NIAID) [ E]" Subje ct : Fw d: urgent: CNN request Sent from my iPhone Begin forwarded message: ------~~ -------- (b) (6)> (b)(6)> (b)(6) From: " Billet, Courtney (NIH/NIAID) [E]" Date: April 21, 2020 at 2:49:39 PM EDT To: "Con rad, Patricia (NIH/NIAID) [E]" Cc: "Routh, Jennifer (NIH/NIAID) [E]" ..:======= -------~~ (b)(6) (b ~):::;, (6) ~ Subject: FW: urgent : CNN request Patty - can you please check with Dr. Fauci if he'd like to speak to Elizabeth Cohen about the treatment guidelines. From: Lane, Cliff (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 2:48 PM To: Billet , Courtney (NIH/NIAID) [E] (b)( ; Pau, Alice (NIH/NIAID) [E] (b)(6)> Cc: Doepel, Laurie (NIH/NIAID) [E] (b)(6); Masur, Henry (NIH/ CC/CCMD) [E]_.:...__..:....:_.:..== (b "'": )::"'" (6) ~;-M_y_le-s,- R-e-na_t_ e ,_ (NI H/0 D) [ E] ------- ------~= (b)(6)> Subject: Re: urgent: CNN request I think Dr. Fauci would want the option of first refusal. He has anticipated he will be asked about these. From: "Bi ll et, Courtney (NIH/ NIAID) [E]" Date: T uesday, Apr il 21, 2020 at 1:35 PM To: "Pau, Alice (NIH/NIA ID) [E]" -------= ---------- Cc: Laur ie Doepe l 11 (NI H/CC/CC MD ) [E '":]-::-: :.::======;;, [E]" .;....:.--=====~~-- (b)(6) Cb =H=6J> CbH6)>,"Masur, Henry (b,;::: )(~6), " Lane, Cliff (N IH/NIA ID) CbH6),"Myles, Renate (NIH/OD) [E]" (b)( 6)> Subject: RE: urgent: CNN request HI Alice - thanks for sending this along. We will confer about how best to handle media requests about the guidelines - we're calling them NIH guidelines and the press release came from NIH, so I'd like to involve the NIH media office in this, hence I've cc'd Renate Myles . I think it's sort of an unsettled question as to who the spokespeople will be. Drs. Lane and Masur - do you have a preference? Also, who is Claire? (The person who forwarded the CNN request to you and Dr. Masur. Would be good to have a last name so we can confer with her as needed going forward.) ------- From: Pau, Alice (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 1:24 PM (b)(6)> To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Cc: Doepel, Laurie (_ N_IH..:.. / _N_ IA_ID ....: )..:[....: E]:..!=-:-=;:-----."'."""."9 (b _)_C6) ~ Masur, Henry (NIH/CC/CCMD) [E] (b)(6)>; Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: FW: urgent: CNN request .;.:::======~~ Hi Courtney, Please see below the request from CNN. Per Laurie, I will forward other reques t s to you. Thanks, Alice From: COVID19 Treatment Guidelines Date: Tuesday, April 21, 2020 at 1:06 PM To: Henry Masur (b)(6),Alice Pau (b)(6)> Subject: Fw: urgent: CNN request Hi Henry and Alice, I am not sure how we want to handle interview requests like this. Would someone on the Panel want to/be allowed to speak to the press about the guidelines? I am happy to politely declin e if we want to handle it that way. It is nice to see that we are being picked up by the press already though. I am glad peop le are already expressing interest. Just let me know! Claire From: Nigam, M inali Date: Tuesday, April 21, 2020 4:03 PM To: COVID19Treatment Guidelines Cc: Cohen, Elizabeth ; Fine, Amanda (NIH/OD) [E] (b)( > Subjec t : urgent: CNN request To the NIH Covid- 19 Treatment Guidel ine Team: My name is Minali Nigam and I work with Elizabeth Cohen at CNN Health . We wanted to reach out and request to speak with someone over the phone involved with the NIH treatment guidelines for covid19. Please let us know as soon as possible for an availab le time today. We appreciate your help, as we inform our viewers of important health information. Best, Minali Dr. M inali Nigam CNN Health (b)(6) (bXS) -PCl1 (b)(5) - Pe l (bX5) -PCI (bX5) -PCI (bX5)-PCI (bX5) -PCI (bX5) -PCI (bX5) -l'U From: Date: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202019 :42:03 +0000 To: Birx, Deborah L. EOP/NSC;Hahn, Stephen;Redfield , Robert R. (CDC/OD) Subject: FW: SCMP: Coro navirus's ability to mutate has been vast ly underestimated, and mutations aff ect dead liness of strains, Chinese st udy finds See below Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci @niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Monday, April 20, 2020 1:53 PM Subject: SCMP: Coronavirus's ability to mutate has been vastly underestimated, and mutations affect deadl iness of strains, Chinese study finds China/ Science Coronavirus'sability to mutate has been vastly underestimated, and mutations affect deadlinessof strains, Chinesestudy finds • The mos t aggressive strains of Sars-CoV-2 could generate 270 times as much viral load as the least potent type • New York may have a deadlier strain imported from Europe, compared to less deadly viruses elsewhere in the United States Stephen Chen in Beijing Published: 10:41pm, 20 Apr, 2020 Updated: 1:33am, 21 Apr, 2020 A team led by Professor Li Lanjuan has studied how the novel coronavirus mutates and possible implications for the pandemic. Photo: EPA-EFE A new study by one of China's top scientists has found the ability of the new coronavirus to mutate has been vastly underestimated and different strains may account for different impacts of the disease in various parts of the world. Professor Li Lanj uan and her colleagues from Zhejiang University found within a small pool of patients many mutations not previously reported . These muta t ions included changes so rare that scientists had never considered they might occur. They also confirmed for the first time with laboratory evidence that certain mutations could create strains deadlier than others. "Sars-CoV-2 has acquired mutat ions capable of substantially changing its pathogenicity," Li and her collaborators wrote in a non-peer reviewed paper released on preprint service medRxiv.org on Sunday. Li's study provided the f irst hard evidence that mutation could affect how severely the virus caused disease or damage in its host. Li took an unusual approach to investigate the virus mutation . She analysed the viral strains isolated from 11 randomly chosen Covid-19 patients from Hangzhou in the eastern province of Zhejiang, and then tested how efficiently they could infect and kill cells. The deadliest mutations in the Zhejiang patients had also been found in most patients across Europe, while the milder strains were the predomina nt varieties found in parts of the United States, such as Washington state, according to their paper. A separate study had found that New York strains had been imported from Europe. The death rate in New York was similar to that in many European countries, if not worse . But the weaker mutation did not mean a lower risk for everybody, according to Li's study . In Zheji ang, two patients in their 30s and 50s who cont racted the weaker strain became severely ill. Although both survived in the end, the elder patient needed treatment in an intensive care unit . This finding cou ld shed light on differences in regio nal mortality . The pandemic's infection and death rates vary from one country to another , and many explanations have been proposed . Genetic scientists had noticed that the dominant strains in different geograph ic regions were inherently different. Some researchers suspected the varying mortality rates could, in part, be caused by mutations but they had no direct proof. The issue was f urther complicated because survival rates depended on many factors, such as age, underlying health conditions or even blood type . In hospitals, Covid-19 has been treated as one d isease and patients have received the same treatment regardless of the strain they have. Li and her col leagues suggested t hat defining mutations in a region might determine actions to fight the virus . "Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations ... into account to avoid pote ntial pitfalls," t hey said. Li was the first scientist to propose the Wuhan lockdown.accord ing to state media reports. The government followed her advice and in late January, the city of more than 11 million residents was shut down overnight. The sample size in this most recent study was remarkably small. Other studies tracking the virus mutation usually involved hundreds, or even thousands, of strains. Li's team detected more than 30 mutations. Among them 19 mutations - or about 60 per cent - were new . They found some of these mutations could lead to functional changes in the virus' spike protein, a unique structure over the viral envelope enabling the coronavir us to bind with human cells. Computer simulation pred icted that these mutations would increase its infectivity . To verify the theory, Li and colleague s infected cells with strains carrying different mutat ions. The most aggressive strains could generate 270 times as much viral load as the weakest type. These strains also killed the cells the fastest. It was an unexpected result from fewer t han a dozen patients, "ind icating that the true diversity of the viral strains is still largely underappreciated," Li wrote in the paper. Professor Li Lanjuan is a leading Chinese epidemiologist. Photo: Xinhua The mutat ions were genes different from the earliest strain isolated in Wuhan, where the virus was first detected in late December last year. The coronavirus changes at an average speed of about one mutation per month. By Monday, more than 10,000 strains had been sequenced by scientists around the globe, containing more than 4,300 mutations, according to the China National Centre for Bioinformation. Most of these samples, t hough, were sequenced by a standard approach that could generate a result quickly. The genes were read just once, for instance, and there was room for mistakes. Li's team used a more sophisticated method known as ultra-deep sequencing. Each building block of the virus genome was read more than 100 times, allowing the researchers to see changes that could have been overlooked by the conventional approach. The researchers also found three consecutive changes - known as tri-nucleotide mutations - in a 60year-old patient, which was a rare event. Usually the genes mutated at one site at a time. This patient spent more than 50 days in hospital, much longer than other Covid-19 patients, and even his faeces were infectious with living viral strains. "Investigating the functiona l impact of this tri-nucleotide mutation would be highly interesting," Li and colleagues said in the paper. Professor Zhang Xuegong, head of the bioinformatics division at the National Laboratory for Information Science and Technology at Tsinghua University, said ultra-deep sequencing could be an effective strategy to track the virus' mutation. "It can produce some useful info rmation," he said. But this approach could be much more time consuming and costly. It was unlikely to be applied to all samples. "Our understanding of the virus remains quite shallow," Zhang said. Questions such as where the virus came from, why it could kill some healthy young people while generating no detectab le symptoms in many others still left scientists scratching their heads. "If there is a discovery that overturns the prevailing perception, don't be surprised." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 202018:01:06 +0000 Jim Yong Kim RE:My art icle Jim : Very nice pape r! Thanks f or sending it . Best, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)( 6) FAX: (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representatives. From: Jim Yong Kim Sen t: Monday, April 20, 20 20 3:00 PM To: Fauci, Anthony {NIH/NIAID) [E] ------- ~= (b)(6):> Subject: My article Tony, Hope you're well and thank yo u again for all that you are doi ng. I got this out today in the New Yorker and I'll be ta lking to most of the Democra tic caucus today about w hat we're do ing in Mass and the developing worl d. Hang in there and let me know if there is anything more I can do . Mass is tough but we're going to have a 1000 contac t tra cers very soon . Every day we learn so much, wh ich is why it's so im po rt ant for everyone to get started . Jim From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 202017 :43:2 1 +0000 EDWARD SCOLNICK Mascola , John (N IH/VRC) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston , Hilary (NIH/N IAID) [El Subject: Attachment s: RE:for your consideration Scient ists_to_Stop _COVID19_ 2020_04_ 15_ FINAL.pdf Ed: Thank you for your note and for sending this. The outline that you provide is exactly in sync with what we are already doing and have definitive plans to do with regard to classic antivirals , monoclonal antibodies, and a variety of vacci ne candid ates. As you know, the candidate developed here at Nll-1 in collaboration with Moderna is well inco phase I crials and at lease 2 ochers are encer ing into phase 1 trials. Best regard::;, Tony Anthony S. Fauci, MD Director National Tnslitu te of Allergy and Infectious Di seases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 Nat iona l Tnslitutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ien t. If you have received this e-mai l in error please infonn the sender and delete it from your mailbox or any other storage devices. The Nat iona l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: EDWA RD SCOLNICK (b)(6) Date: Sunday, April I 9, 202 0 5: 18 PM To: Fauci, Anthony (NIH/N IATD) [El T""'!"'~~-!""' (b_) _C6) ,..>________ Cc: David R. Liu (b)(6) ; Schreiber, Stuart _______ Cb _)_(6) _,> ; Ramnik Xav ier ___________ Subject: for your consid erat ion ------~~ ~~ (b)(6) ; Michael Rosbash Cb _)_(_ 6) Tony . I hope your mail box is not so full that lhere is room for this. A group of concerned scient ists from different parts of the country was organized to tr y to encap sulate and focus tbe national effott against Covid. This document has been share d with the White House although we are not sure if it has had any effect on their plans. It has also been shared with The Gates Foundation and a few other business and academic leaders . We rhink we have been fairly comprehens ive in our cons iderations and recommendations . I hope you will find this helpful. We would greatly appreciate a conversation with you after you have had an oppo1tunity to digest the content of the proposal. lfthere is anything else we can do to help you in this National emergency, we stand ready to help. When I was at Merck ,we led the successful effort to make HIV a manageable disease and we dramatically lowered the death rate as a result of the dmgs we made ,and the first triple therapy trial during the HIV pand emic. We hope we can help do the same for The Covid Pandemic Best wishes Ed scolnick From: Fauci, Anthony (NIH/N IA ID) [El Tue, 21 Apr 202015 :12:29 +0000 Grady, Christine (NIH/CC/BEP) [El FW: Thank you Date: To: Subject: See part about you. Anthony Q S. Fauci, MD Director National Institute of Allergy and Infectious Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 Diseases National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (30 96~ 09 E-mail: (b)(6) The information m t 1se-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patric ia (NIH/NIAID) (E] Date: Tuesday, April 21, 2020 11:07 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( --------- ------~= _______ ..... > (b)(6) Subject: FW: Thank you This is a cute note ...you can skip most of it and see highlight - that is the cute part Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive informat ion . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Instit ute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----Original Message----From: JOAN HUSSEY (bH6l Date: Tuesday, April 21, 2020 9:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you --------,;- s--=, ---------=-:- = --------- (bH 6)> Dear Dr. Fauci, I just wanted to say thank you for everything you are doing to educate us in this country , and keep us safe during this horrendous coronavirus pandemic. I can't even begin to imagine how difficult it is to maintain your composure and persevere with your focus, bei ng constant ly in the public eye and also trying to expert ly guide a president who seems more preoccupied with his own image (and sound of his own voice), and political aspirations than with the actual well being of his country's citizens. By now, it should be perfectly clear to us t hat we can't have a healthy economy wi t hout a healthy population. (b)(6) I (bH ~ We all have been diligent about staying at home I (b)( ~ ordering food and other t hings to be delivered to our house (we all wash our hands 'religiously') . (b)(6) is the only one of us who occasionally goes to a grocery store or drug sto re if necessary and t hen, he always wears a mask, gloves, and keeps at least six feet between himself and anyone else, and gets in and out as quickly as possible. In addit ion, (b)( 6) are so intent on keeping me we ll and alive, we haven't even, any of us, physically visited with each other , in person, inside our house for months . In the past two months, I've been outside only four times - twice on our deck and twice in my car, dropping off a couple of shopping bags at a friend's house and at CbH 6) group home - both times leaving the bags in the dr iveway, and then driving right back home . I'm so t hankful for FaceTime, but we miss hugs and kisses. I know all this must sound extreme, and it is, but I'm terr ified of becoming a statistic so we're doing whatever we can to stay healthy for ourselves and one another. -------- (b)( 6) Cb H(i)jMy family is hearing what you're saying and taking your advice. -----I'm sorry this email is so long but my intention, more than anything, is to thank you for your wisdom and advice, both grounded in years of experience. I worked at NIH for about 25 years - in the CC, in NCI, and in Human Genome. I met you once, briefly , about 40 years ago(+/ -) in Bldg. 31's fitness room . I had been working in the CC,in the Patient Activities Dep't. (on the POBout - and inpatient units)at the time. I was incorrectly using a piece of equipment and you were kind enough to come over and show me the correct way to use it. I recognized you immediately , and have never forgotten that experience and how gracious you were . I'm well aware from the news that you are up against some very tough people and some very tough times but please know you also have an army of grateful followers in this country who are comp letely convinced that what you are advising is in their very best interest. Thank you again for all you've done for all of us over the years. My family and I are more grateful than I can e> On Apr 19, 2020 , at 10:34 PM , Charles TvlcCall > --------- (b)(6) > wrote: > Dear Tony and Dan, > > (b) (4) > > > Thank you for cons idering this idea. Be safe. > > > > Cash > > > > Sent from iPad > Charles (Cash) McCall, MD > Professor oflntema l Medicine, Translational Sciences , Microbiology & Immunology > Wake Forest University School of Medic ine > Wake Forest Biotech Place, su ite 350, room 3W-007 > 575 N. Patterson Avenue > Winston-Salem , NC 27101 > (bX5) -PCI From: Fauci, Anthony (NIH/N IA ID) [E) Date: Mo n, 20 Apr 2020 15:03:51 +0000 To: Conrad, Patricia (NIH/NIA ID) [E) Subject: FW: A Nat ional Test ing Action Plan by the Rockefeller Foundation: Embargoed ti ll m idnight Monday Apr il 20 Attachments: RF National COVID-19 Testing Act ion Plan_LASTFINAL_04.20.2020.docx Set up Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)( 6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: O'Connor, Eileen Date: Monday , Apri l 20, 2020 7:47 AM To: Fauci, Anthony (NIH/NIA ID) [E] ; Anthony .s.fauci@n ih.gov; AFAURCl@niaid.nih.gov Subject: A Nat iona l Test ing Action Plan by the Rockefeller Foundation: Embargoed t ill m idn ight Monday April 20 Dear Tony: Thank you for all you are doin g. Not sure you r emembe r me Cb) ~ we talked a lot when 1 was at CNN. I have not wanted to bother you but wanted to make sure you had the National Testing Action Pla n that we have put together with top researchers from all the various roadmaps, etc. l joined The Rockefell er Foundat ion after working in Afghanistan and Pakistan with State and coerced Christy Feig to join me. We would be happy to get on a call today w ith Raj and Jonathan Quick and other autho rs like Mike Pellini and Mark McLellan and Rick Klau sner. ----------------- Given our history with public health and our abil ity to convene, we hoped we could help by working out a consensus plan . I have been briefing Caleb McCarry at the White House. We have worked with industr y to also figure out the solution s to the supply chain issues and the other logistical issues. We are going to put $10 million into helping this standup. This plan doesn't just say what we need but the steps to get it done to open more safely. Please let me know if you would like a call. Regards Eileen Eileen O'Connor Senior Vice President Communications, Policy and Advocacy The Rockefeller Foundation Office: 212 852 8436 Mobile: Cb> C6J eoconnor @rockfound.org www.rockfound .org (For sched uling purposes, please contact my assistant, (b)( CbH6),at From: Date: To: Subject: Att achm ent s: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 14:22:57 +0000 Anderson, Jennifer (NIH/NIAID ) [E] FW: Potential Postbac IRTA Fellowship CV4.19.pdf Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Monday, April 20, 2020 9:00 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Potential Postbac IRTA Fellowshi p --------=-:-:= > --------- (b)( (b)(6) (b)(6 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mo n, 20 Apr 2020 11:58:51 +0000 Billet, Courtney (NIH/N IAID) [E] RE:ASF: Today's YES Network interview Than ks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: Billet, Courtney {NIH/NIAID) [E) (b)( > Se nt : Monday, April 20, 2020 7:55 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) (b)( ; Folkers, Greg (NIH/NIAID) [E] --------- Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: ASF: Today's YESNetwork intervi ew You have an interview t oday with Jack Curry of the YES Network (Yankees) . Just last night, The NY Post ran a story that includes Jack among the many sports broadcasting stars that have come out of Fordha CbH6);Jack and I have t alked about this). Thought you might like to see it. Parts of your interview are also going to run on Michae l Kay's show, and Kay also features prominent ly in this piec e. How Fordham has produced a generation of sports media stars April 19, 2020 I 4:04pm I Updated April 19. 2020 I 9:16pm John Giannone , Michael Kay and Mike Breen; Chris Carrino Co urtesy of M ichael Kay, Chris Carrin o Long before he was an electee to the Basketball Hall of Fame , Mike Breen was an intimidated 18-year-old freshman attending a workshop at Fordham's renowned college radio station, WFUV, in the fall of 1979. Breen felt sheepish next to the juniors and seniors leading the seminar and contemplated delaying the start of his broadcasting training. Soon, a couple of upperclassmen, including future NBA writer Dave D' Alesandro, made him feel more comfortable. But he still didn't have any friends until one day on campus he saw a confident sophomore trying to sweet talk a young woman. "I know you like me," he said. "I can see it in your eyes." The woman responded by saying she would not date him if he were the last man on earth. She essentially was saying, " See ya" .. . to Michael Kay. That is how Breen first became friends with Kay. "For him to have the confidence to do this in front of everybody with this beautiful student , I thought, 'Man, this guy has a great sense of humor ,'" Breen said. Four decades later, Breen and Kay are still good friends. Michael Kay and Mike Breen Courtesy of Michael Kay Fordham, the private Jesuit university in The Bronx that launched the legendary Vin Scully, for decades has been a powerhouse sportscasting pipeline , especially in New York. And the school ties that first united Breen and Kay are webbed throughout the industry . Fordham is the alma mater for the voice of the NBA Finals/Knicks (Breen, Class of 1983), the Yankees' lead TV play-by-player/ESPN New York afternoon radio host (Kay, '82), the voice of the Giants (Bob Papa, '8 6), the radio voice of the Nets (Chris Carrino , '92) MSG 's John Giannone ('86) , YES' Jack Curry ('86) , WFAN's Paul Dottino ('86) and YES/ESPN's Ryan Ruocco ('08). And that's just New York-based sportscasters. For good measure, the schoo l produced CBS' Spero Dedes ('01), ESPN's Tony Reali ('00) and the Washington Nationals' Charlie Slowes ('83). There are many more, and not just in front of the camera. If you need a field producer, Jim Johnson ('86) works for ESPN. A radio engineer? WF AN's Chris Majkowski ('89) will set things up. Media relations? Louis Ban-icelli ('09) is leading things at MLB Network. Like everyone else, they are all dealing with the halt of sports due to the coronavirus pandemic. It is a jan-ing timeout for people so used to being on the run. ~ Ryan Ruocco, Mike Breen Courtesy of Ryan Ruocco Take Carrino, who has done so much to raise money and awareness for facio scapulo humeral dystrophy (FSHD), a form of muscular dystrophy that afflicts him. A fundraising event was supposed to take place in March at a Ne ts game at Barclays Center. His 10th annual fundraising dinner, correspon ding with his 50th bi1thday, was slated for August, and now is in question. "I don't know if it is going to be safe to have people together still," Carrino said. "Are the restrictions going to be there in terms of how many people can gather in one place? The other aspect of it for me is: How comfortab le am I asking peop le for money when I know the economy and certain businesses are affected so badly?" Ruocco was supposed to get married in Italy in June. He and his fiancee, Andrea Ferzoco, are now going to punt the wedding until June 2021. "It sucks," Ruocco said. "Arldrea and I were so excited and so were our guests. We have been feeling all the joy leading us to this. There are people dealing with much more dire circumstances than rescheduling a wedding. That is kind of the perspec tive we have tried to take." While most of the successful sports media alumni are worried about the current direction of Fordham and WFUV because of a de-emphasis on sports during the pandemic , to a man they say how Fordham molded them and led them to where they are today. They were helpe d by famous names such as the legendary Marty Glickman, a mentor , and Stan Fischler, who taught classes. Then there were the less famous, equa lly instrwnental figures in the program, such as Bob Ahrens, who ran WFUV as its executive producer during many of these notable students' formative years. John Giannone punting at FordhamCourtesy of John Giannone The experiences that they shared forged many of them , such as Breen and Kay, into close friends. Giannone went to Fordham after being recruited to be a punter on the football team. During training camp his freshman year, he quickly figured out the third-string punter would never see the field. He went to Kay, then the WFUV sports director as a senior, to try to help on the station. Kay said Giannone could do stats for him during the football season. Kay went on to work at The Post, and later helped Giannone land an entry-level position at the paper. When Giannone transferred into television at CNN/Sports Illu strated, it was through a Kay connection. And Giannone landed at MSG Network after Kay left to become the TV voice of the Yankees when YES Network began. When it was Giannone's turn as WFUV spo rts director, he made Papa and Curry a play-byplayer and an analyst when they were sophomore s. WFUV also got its staff access to locker rooms at places like Yankee Stadium and Madison Square Garden to learn the craft next to profes siona ls at the highest level. That remains largely true today. "WFUV allowed you to believe you were a profes sional broadcaster before you really were," Curry said. "We were in the heart of New York City, and, even ifwe weren't Marv Albert, we felt as if what Marv Albert was doing for the Knicks, we were doing for Fordham." There is a lineage that unites. Carrino learned how to describe the geography of a ba sketball court from Glickman. Later , Carrino returned to Fordham and taught Ruocco the same lessons. These days, at some Nets games, Ruocco is on TV , sitting next to Carrino, calling the game on the radio. Jack Curry Courtesy of Jack Curry Papa also was mentored by Glickman. Papa and Carrino each were told by their fathers that if they majored in communications, they would have to pay for schoo l themselves. Both ended up in the Business School , but had their eyes on WFUV the whole time. Carrino ended up working as a producer for Papa , beginning when Papa hosted a tailgate show on WF AN . Carrino eventually followed Papa as the radio voice of the Nets. The Fordham sports alums want everyone to be safe during this time get back to what they love to do. and they can't wait to "I 'm desperate to get back to work ," Breen said. "I'm hoping there is NBA basketball. This is the best time of the year ." From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 11:14:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: the Strategy document COVIDvaccine editorial_prefinal April19 wfigure.docx To: Subject: Attachme nts: Email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Corey MD, Larry Date: Sunday, April 19, 2020 11:45 PM To: Fauci, Anthony (NIH/ NIAID) [El (b)(6)> ------~~ -------> Cc: Mascola, John (NIH/VRC) [E] --------Subject: the Strategy document (b)( ·>; Conrad, Patricia (NIH/NIAID) [El (b) ~ (b)( >; Miner PhD, Mindy (b)(6) Here is the working draft of the article for the NEJM . It, in my opinion, reads really well . I have embellished it today with a figure that conceptual ly outlines what we are talking about; the old axiom that a picture is worth a thousand words . The editorial guide lines of the NEJM has 2 potential categories. One is Perspectives which is 1200 words an 5 references . We are at 1750 words and I t hink losing 500 words takes away a lot from the message . The other category is a special report wh ich is over 2500 words and allows lots of references ( 40) I think this is best and was one reason I thought about adding the conceptua l fig ure which does outli ne in a single picture what we are talking about . Tony, If you feel its best to have Francis on this paper we both support it . Your call . I do however lean on includ ing Francis . I would say politicly to achieve our goal and bring all these companies into the ten t while you are away at the White House having him buy into t his plan through the ACTIVprog ram seems important to us . I think we get to our goal if he is out there publ icly embracing this; using the NIAID networks labs DSMB and the correlates programs . This type of granula rity really puts him deep into understanding what we are doing . If this means you are first and he is last author we are ok with that, For me I need to have him use me for interfacing with the company in defining these collabo rations . If you were present all the time this would be unnecessary , but as he will be the link with BARDA linking him to John and I increases the likelihood of success. (b)(6) Ok enough .. as they say on the news Goodnight .. Larry From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/N IAID) [E) Mo n, 20 Apr 2020 02:39:49 +0000 'Thomas Quinn' FW: Fauci pho to Fauci ISSTDR1983.pdf Thanks, Tom! From: From: Thomas Quinn (b)(6)> Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) (E]-----Cc: Hunter Handsfield Subject: FW: Fauci photo -------- ~= (b)(6)> Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis . Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives - 1983 in Seattle ). All the best, Tom (b)(6) Stay healthy! From: Hunter Handsfie ld Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Quinn Subject: Fauci photo (b)(6) Hi, Tom . Going through old boxes I came across this, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him . Cheers- Hunter H. Hunter Handsfield, MD Professor Emeritus of Medicine Center for Al OSand STD University of Washington Phone +1 206 935-5225 Mobile (b)(6) From: Date: To: Subject: Attachme nts: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:58:31 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Fauci photo Fauci ISSTDR1983.pdf Email from Tom Quinn to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Thomas Quinn (b)( Date: Sunday, April 19, 2020 6:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hunter Handsfield Subject: FW: Fauci photo ------~~ (b)(6) Hi Tony, It was great to see you and present our work to you this last Friday. I really enjoyed our discussion and feedback. As I said on zoom, we all really appreciate your leadership in the COVID-19 crisis. Thank you for providing the guiding way through this . (b) (4) In the meantime, your photos are getting passed around and Hunter Handsfield wanted you to have this one (from the HIV archives-1983 in Seattle). All the best, Tom (b)(6) . Stay healthy! From: Hunter Handsfie ld (b)(6) Date: Sunday, April 19, 2020 at 3:52 PM To: Thomas Qu inn Cb H6J> Subject: Fauci photo Hi, Tom . Going through old boxes I came across t his, from 5th ISSTDR, Seattle 1983. Give Tony my greetings if you forward to him. Cheers- Hunter H. Hunte r Handsfi eld, MD Professor Emeritus of Med icine Center for AIDS and STD Univers ity of Washington (b)( 6) Phone ➔ Mob ile Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Mon, 20 Apr 2020 01:56:21 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: A proposal to stop COVID-19 and reopen our schools and businesses From: Date: To: Subject: Email from David Liu to FC with a cc to you . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Alle rgy and Infectiou s Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: David R. Liu (b)(6) Se nt : Sunday, April 19, 2020 9:08 PM To: Collins, Francis {NIH/OD) [E] Cc: M ichael Rosbash -------::-::-=, > _:_....:....::....:.!===-=---::--(b)(6)>; Ramnik Xavier EDWARD SCOLNICK (b)( (b)(6l>; Stuart Schrei ber (b)(6) >; Ben Cravatt ======~~ (b)(6J>; Lane, Cliff (NIH/NIAID) (NIH/NCATS) [E) (FNIH) [T) (b)( (b)(6)>; Michael Z Lin ; Fauci, Anthony (NIH/NIAID) [E] [El (b)(6) •>; A usti n, Christopher (b)(6J>; W ha lley, David (FNIH) [T) CbH6J;Tabak, Lawrence (NIH/OD) [El (b)( (b)(6J>; (b)(6); Freire, Maria CbH6J>;Thomas Cahill > Subject: Re: A proposal to stop COVID-19 and reopen our schools and businesses Thank you, Francis, for your speedy re ply. Please let us know if we can help ACTIV, Fauci, or any other leaders who might want to engage. Best, David David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Technolog ies in Healthcare Broad Institute Core Institute Member and Vice-Chair of the Faculty Director of the Chemical Biology and Therapeutic Sciences Program Howa rd Hughes Medical Institute Investigator Harvard University Professor of Che mistry and Chemical Biology 75 Ames Street Cambrid ge, MA 02142 On Apr 19, 2020, at 8:48 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Dear David et al., Thanks for forwarding this ve ry thoughtful document, which presents a series of important recommendations - most of which I agree with. I don't know if you saw Friday's announcement (attached) of the new public private partne rship called ACTIV (for Accelerating COVID-19 Therapeutic Interventions and Vaccines), but it has taken on most of the points you raise in sections 1 - 3 of your letter. I share your hopes that remdesivir w ill show benefit, and the current large NIH-sponsored RCT has completed enrollment and should reveal results in about a month. But of course we want to test multiple other interventions - both small molecules and antibody-based therapies, so we need our trial system to be optimized like never before. I will share your letter with the leaders of ACTIV, who are working with unprecedented speed to prio ritize the next set of therapeutic candidates as well as pushing vaccine development programs to adopt exceptionally creative trial designs to test safety and efficacy (with fu ll engagement by FDA). Best regards, Francis From: David Liu (b)(6)> Date: Sunday, April 19, 2020 5:20 PM To: OD Labc (NIH/OD) (b)(6) ; Collins, Francis (NIH/OD) [E] (b)(6) Cc: Michael Rosbash Ramnik Xavier -------...!:===~~-----------~~ EDWARDSCOLNICK (b)(6)>; (b)(6)>; -:--:-".":""""--;;:::========~~ Schreiber (b)(6) ----==== Michael Z Lin (b)(6)>; (b)(6); Stuart Ben Cravatt (b ~ )~(6) ~----- Subjec t: A proposal to stop COVID-19and reopen our schools and businesses Dear Francis, I hope you are well. I write on behalf of a group of citizen-scientists, most or all of whom you know. Motivated solely by our desire to help defeat the serious threat our nation and the world now faces, we wrote a set of four actionable, non-partisan proposals (attached ) to produce safe and effective COVID-19therapeutics and vaccines in the shortest possible timeframe, and to reopen our society in a manner that reduces t he risk of future COVID-19outbreaks. We hope you find these ideas interesting, and might be willing to share this set of proposals with Dr. Tony Fauci, along with our willingness to discuss any part of the proposals with him if we can be helpful. We understand from our efforts to contact Dr. Fauci through email routes that his standard inbox may be too overwhelmed for our proposal to reach him. The four proposals attached describe: (1) How to rapid ly repurpose an antiviral drug to treat COVID-19 pat ients; (2) How to expedite the development of human antibody drugs to treat patients and to provide short-term protect ion for healthy individuals; (3) How to develop COVID-19 vaccines on an expedited time scale; and (4) How to reopen our businesses and schools in a manner that reduces the risk of future outbreaks and deaths. Thank you for any help or thoughts you might be able to provide. Sincerely yours, Ben Cravatt (Scripps), Lynn Goldman (GWU), Akiko Iwasaki (Yale), Scott Kemp (MIT), Michael Lin (Stanford), David Liu (Harvard/Broad), Michael Rosbash (Brande is), Stuart Schreiber (Harvard/Broad), Ed Scolnick (Broad), Jonathan Simons (PCF),and Ramnik Xavier (MGH/Broad) David R. Liu Richard Merkin Professor and Director of the Merkin Institute of Transformative Techno logies in Healthcare Director of the Chemical Biology and Therapeutic Sciences Program Core Institute Member and Vice-Chair of the Faculty, Broad Institute Investigator, Howard Hughes Medical Institute Thomas Dudley Cabot Professor of the Natural Sciences and Professor of Chemistry & Chemical Biology, Harvard University 75 Ames Street Cambridge, MA 02142 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 01:25:42 +0000 bgertz@wash ingtontimes.com Mi ller, Katie R. EOP/OVP;Short, Marc T. EOP/OVP Scientific paper on origin of coronav irus From: Date: To: Cc: Subjec t : Bill : Here are the li nks to the scientific papers and a commentary origins of SARS-Cov-2. about the scientific basis of the The proxima l origin of SARS-CoV-2. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med. 2020 Apr;26(4):450-452. do i: 10.1038/s41591 -020-0820-9 . No abstra ct availa ble. A Genomic Perspective on the Origin and Emergence of SARS-CoV-2.Zhang YZ, Holmes EC.Cell. 2020 Apr 16;181(2):223-227 . do i: 10.1016/ j .cell.2020 .03.035. Epub 2020 Mar 26. Also this statement from Eddie Ho lmes ht tp s:/ / bit. ly/2 yml UGe Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. On Apr 19, 2020, at 2:21 PM, Bill Gertz wrote : Katie, Dr. Fauci on Friday said he would share a scientific paper with the press on the origin of the coronav irus. Can you please help me get a copy of that paper? Thanks in advance. Bill Gertz National Security Correspondent @Bil!Gertz I direct 202-636-327 4 TheGertzFile .com 3600 New York Ave NE I Washington DC, 20002 The inform ation contained in t his electronic transm ission is intended for t he exclusive use of the individuals to whom it is addressed and may conta in informat ion that is pr ivileged and confidentia l, the disclosure of which is proh ibited by law. If the reader of th is transm ission is not the intende d recipient , you are hereby not ified that any disseminat ion, distr ibut ion or copying of th is commun icati on is str ictly prohibited. In addit ion, any unauthor ized copying, disclosure or distribut ion of the materia l in th is e-mai l and any attachments is strict ly forbidden. From: Date: Fauci, Anthony (NIH/N IAID) [El Mo n, 20 Apr 2020 01:22:40 +0000 Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl RE: IMPORTANT To: Cc: Subjec t : Thanks Greg. Patty: Please respond to Dr. Dzau's questions . Thanks, Tony From: Folkers, Greg (NIH/NIAID) [El ------- Date: Sunday, April 19, 2020 7:06 PM To: Conrad, Patricia (NIH/NIAID) (El ----- (b)( > (b ~ ) ~(6)'>; Fauci, An t hony (NIH/NIAID ) [ El (b)(6) ------- Cc: Barasch, Kimberly (NIH/N IAID) [C] Subject: RE: IMPOR TANT (b)( Patty I had spoken to ASFabout using a few slides and he said yes/ I will have them done short;y • V Dzau: I will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic. Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited number of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below . • Jeremy Farrar wi ll discuss the global response to the pandemic , drawi ng from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board . • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019-20 coronavirus pandemic . • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARSCOV2, insights into its pathobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta wil l comment on the health system response to the pandemic and challenges related to communication and public engagement in responding to COVID-19. From: Conrad , Patricia (NIH/NIAID) [E] Date: Sunday, April 19, 2020 7:01 PM ------ ----~ To: Folkers, Greg (NIH/NIA ID) [E] ~----- (b)(6l> = (b _H_'?)>; Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/ NIAID) [E] (b)(6)> ------ (b)(6)>;Barasch, Kimberly (NIH/NIAID ) [C] Subject: FW: IMPORTANT We need to discuss tomorrow on our daily meeting/call - do you want to do slides. Again this event is on a Saturday and is tentat ive as we do not know when the TF meeting will be scheduled that day. So - if you can do it - will you use slides? So if you cant do th is - do you want a surrogate and who? I w il l make sure David is o n board f or zoom . From: Dzau, Victor J.< VDzau@nas.edu> Date: Sunday, April 19, 2020 3 :11 PM -------~~ Cc: Fauci, Anthony (NIH/NIAID) [E] ~=====:--=--;-~:!,._-----------~~ To ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Mun, Jenny Subject: IMPORTANT ---------------- (b)(6) Dear Patty, I hope this finds you well. I know how terribly busy Tony is and I hate to trouble him, however, the NAS Annual Meeting panel on COVID-19 is less than a week away and my team needs answers to the questions below . Can you call this to his attention or assist him in providing the signed form and requested informat ion? We hope to have this by Tuesday {4/23) morning, if possible. • Please provide a cell number where you can be reached in case you do not connect in time {if you prefer, you can provide the number of your assistant if they w ill be able to reach you directly by cell or at home). • Will you have slides to display during your ta lk? • Are you able to use Zoom 'share your screen' to show the slides directly during your talk or do you need someone from NAS to show your slides for you? • Will you need a test session with our Zoom techs? Please let me know as soon as possible as staff are available to hold training sessions through Monday, April 20 (9 AM to 5 PM EDT). • If you would like to promote your participation in our meeting on social media, please let me know the contact of your social media contact from your institution . Finally, because this is going to be a remote meeting, we would like panelists to log into Zoom 30 minutes before the session starts- that is at 1:30 pm ET to go over the technology and any last minute speaker prep. So far, more than 800 Academy members have registered for the meeting and there wil l be additional members of the public and possibly the press tuning in. Best, Victor (bX5)-PCl1 Fauci, Anthony (NIH/NIAID) [E) Sun, 19 Apr 2020 03:29:42 +0000 Peter Daszak RE:Thank you for your public comments re COVID-19's origins From: Date: To: Subject: Peter: Many thanks for your kind note. Best regards, Tony ------------------~~ (b)(6) From: Peter Daszak Date: Saturday, Apr il 18, 2020 9:43 PM To: Morens, David (NIH/NIAID) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( 6) > Cc: Stemmy, Erik (NIH/NIAID) [E] (b)(6)•>; Erbelding, Emily (NIH/NIAID) [El (b)(6) (b)(6)> ; Aleksei Chmura Subject: Thank you for your public comments re COVID-19's origins Importance: High ---------- --------- ------------ Tony (cc'ing David so that you might pass th is on to Tony once he has a spare second) As t he Pl of the ROl grant publ icly targeted by Fox News reporters at the President ial press briefing last night, I just wanted to say a persona l thankyou on behalf of our staff and collaborators, for publicly stand ing up and stat ing that the scientific evidence supports a natural origin for COVID-19 from a bat-tohuma n spillover, not a lab release from the Wuhan Institu te of Virology. (b) (7)(A) From my perspective, your comments are brave, and coming from your t rusted voice, wi ll help dispel the myths being spun around the v irus' origins . Once this pandemic's over I look forward th anking you in person and let you know how important your comments are to us all. Cheers, Peter (b) (7)(A) From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sun, 19 Apr 2020 01:23:00 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: cotton swabs Followup email from Jake Tapper. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Jake Tapper (b)(6) Date: Saturday, Apr il 18, 2020 4:53 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Re: cotton swabs ------- (b)(6)> Got it Thanks On Sat, Apr 18, 2020 at 4 :52 PM Fauci, Anthony (NIH/NIAID) [E] ------- CbH > w rote: This is w hat I was ref errin g t o. They are not ready fo r pr ime tim e, since th ey have to get th e right med ia and w rapp ing. Subje ct: Qtip announcement https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-gatesfoundation-unitedhealth-group-guantigen-and-us-cotton Coronavirus (COVID-19) Update: FDA, Gates Foundation, UnitedHealth Group, Quantigen, and U.S. Cotton Collaborate to Address Testing Supply Needs The U.S. Food and Drug Administrat ion announced a further expansion of COVID-19testing options through the recognition that spun synthetic swabs- with a design similar to Q-tips - could be used to test patients by collecting a sample from the front of the nose. As part of this effort, U.S. Cotton, the largest manufacturer of cotton swabs and a subsidiary of Parkdale-Mills, developed a polyester-based Q-tip-type swab that is fully synthetic for compat ibility with COVID-19 testing. Harnessing its large-scale U.S.-based manufacturing capabil ities, U.S. Cotton plans to produce these new polyester swabs in large quantities to help meet the needs for coronavirus diagnostic testing. "This action today demonstrates the ingenuity that results from the FDA working in partnership with the private sector . The Trump Administration has been working side-by-side with our industry partners to fight this pandemic, and today is a great example of that work. We appreciate work by UnitedHealth Group, Quantigen, and the Gates Foundation to perform and support the clinical studies necessary for this advancement. We also want to acknowledge U.S. Cotton's efforts to manufacture a new type of swab for COVID-19 testing tha t can be produced at scale. We appreciate the work of these collaborators to consider how these test supplies could be broadly distributed to meet not only the testing needs of t he United States but also global needs around the pandemic. All of these actions by th ese American organizations will help continue to expand our testing capability," said FDA Commissioner Stephen M. Hahn, M .D. This finding that spun synthetic swabs could be used for COVID-19 test ing is based on results from a clinical investigation that represents a collaboration between the FDA, UnitedHealth Group, the Gates Foundation, and Quant igen. The type of test ing at the front of the nose used in th is study is notable because it allows self-collection by patients the reby limiting exposure of healthcare providers; it is more comfortable fo r patients and it can be performed by a swab t hat is more readily available and manufacturab le at scale. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6} The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Fauci, Anthony (NIH/N IA ID) [El Date: Sat, 18 Apr 2020 22 :21 :02 +0000 To: Corey MD, Larry;Conrad, Patricia (NIH/NIAID ) [El Mascola, John (NIH/VRC) [E) Cc: RE: Subject: Attachments : (b)(6) COVIDvaccine editoria l_16April 7pm - with Fauci edits.docx Larry: I have gone over th e manuscript and have mad e a number of edits that are tracked into the attached document. Please take a look, accept the changes (unless you have issues with them) , add the references and then let us discuss next steps, i.e. add or not Francis to authors and where in the order. John: Please also give it another good look. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Corey MD, Larry (b)(6);, Date: Saturday, Apr il 18, 2020 12:34 AM To: Conrad, Patricia (NIH/NIAID) [El-------~ (b)( =>; Fauci, Anthony (NIH/NIAID ) [El (b)(6)> Cc: Mascol a, John (NIH/VRC) [El Subject: work ing draft of NEJM Cb >0'1> Here is the workin g dra ft . My manuscript ty pist too tired to work tonight so it reflects several changes I made tonight ; it should be readable ; Larry From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:40:34 +0000 Auchincloss, Hugh (NIH/NIA ID) [C) Conrad, Patricia (NIH/NIAID) [E);Greg Folkers FW : You are a Hero (b)(6) --::--:-:-----;=======-== --------- (b)(6)) Please see me about thi s on Monday. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------------=-=~ --------- From: Kathy Ireland Date: Tuesday, April 7, 2020 4 :56 PM To: Fauci, Anthony (NIH/NIAID) [E Subject: You are a Hero (b)(6) (b)(6) Dear Dr. Fauci, Thank you for everyth ing you 're doing for Amer ica and the world. I'm wr it ing to you today, rather than calling, because it 's impossible to imagine the degree to wh ich leading science duri ng this COVID-19 pandem ic is impacting your life and your fami ly. Please know, that your wisdom and passion brings so much comfort to millions, including our family and me, specifi cally. You may recall from our previous talks, that (b)(6) What a vicious virus, Dr. Fauci ... unlike anything I've ever seen. In addition to my work as Ambassador for the Elizabeth Taylor AIDS Foundation, it is also an honor and responsibility to serve as International Youth Chair for the Nationa l Pediatric Cancer Foundation . In that position , people approach with questions for our government t hat I am uncomfortabl e giving opinion s on in ignorance. So reluctant to bother you - I'm seeking to learn who at the NIH I should bring this to ? (b)(4) Thank you so much for all that you do . Always, Kathy From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 20:21 :32 +0000 To: (b)(6) (b)(6) Subject: Attachments : FW: article and bb rim The Mentor Who Mad e Dr. Anthony Fauci - WSJ - large text.pdf This article about my relations hip with Shelly Wolff is worth reading Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Building 31, Room 7 A-03 Diseases 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Barton Haynes, M.D. Date: Thursday, Apr il 16, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: article and bb rim --------, .....,..,= (b)(6) Hi tony: Glad this worked out. Wonderful article. Great trib ute to both you and Shelly. But the socks in the last picture ....... (b)(6) So when the pandemic is over or when you are down there and want a break, I can put you in touch wi th him to see the Regis bb goal. He has been following your career for many years. Very nice fellow . Thanks for all you are doing Tony , it on ly sounds like it is getting more and more difficult . But you are doing an amazing job .... So proud of you and that ._______ Best Bart Cb _>...,. < From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 20:12:02 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [El FW: From Jack Curry/ YES Networ k (Yankees) Have we decided t o set t his up. Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIAID) [E) (b)(6) Se nt : Thursday, Apr il 16, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6>:>; Routh, Jennifer (NIH/NIAID) [E] (b)(6); Folkers, Greg {NIH/NIAID) [E] (b)(6)> Subject: ASF: From Jack Curry/ YESNetwork (Yankees) ------~~ --------- Jack Curr y (broadcaster with the YESNetwork, which is like MASN, but for the Yankees) is appealing to you as a New Yorker and lifelong Yankees fan for a 10-minute interview via Zoom. Jack covered the Yankees for 22 years at the NYT. The interv iew would run on YES(largest regional sports network in the country) as the focus of one of the or iginal shows they are producing 3x/week called "YES,WE'RE HERE." It would be ru n across all of their social med ia platfo rms (reach of over 1M). They would also air clips on the M ichael Kay Radio Show (TV play-by-play announcer for the Yankees), which is simulcast on YESand is the highest-rated drive time talk show in New York. Questions below , including a few at the end about your lifelong baseball fandom . Is this someth ing you' d be willing to do? If so we will seek clearance. POSSIBLEQUESTIONS DOCTOR FAUCI , I KNOW YOUR DAYS ARE FILLED WITH OFFERING ADVICE AND COU SEL TO SO MANY PEOPLE ABOUT THE CORONA VIRUS. WITH THE SOBERING POSITION WE HA VE BEEN IN FOR A WHILE, WHAT WOULD BE YOUR MOST URGENT MESSAGE TO AMERICANS? THE PHRASE 'FLATTENING THE CURVE' HAS BECOME COMMONPLACE IN OUR VERNACULAR IN RECENT WEEKS. HOW MUCH CLOSER ARE WE GETTI G TO FLA TTENJNG THE CURVE? YOU'VE SAID SEVERAL TIMES THAT THE VIRUS IS THE CLOCK. WHAT IS THE VIRUS TELLING YOU ABOUT THAT TIME FRAME? AS THE COUNTRY TR TESTO WORK ITS WAY BACK, THERE HAS BEEN SPECULA TTON ABOUT HOW PROFESSIONAL SPORTS CAN RETURN. WHAT ARE YOUR THOUGHTS ON HOW, FOR INSTANC E, MAJOR LEAGUE BASEBALL WOULD BE ABLE TO ST ART ITS SEASON? BASEBALL IS A SPORT 1N WHICH SHAKING HANDS IS AS COMMON AS BALLS A D STRIKES. NOT JUST IN BASEBALL , OBVIOUSLY, BUT IN LIFE OVERALL , HOW MUCH DO YOU ADVOCATE NOT SHAKIN G HANDS ANYMOR E? THE NEW YORK TIMES REFERRE D TO YOU AS THE EXPLAINER-IN-CHIEF IN COM PLIMENTING YOUR ABILITY TO SPEAK BLUNTLY AND TRUTHFULLY. SO HOW SHOULD AMERICANS PLAN ON BEHA YING AS WE MOVE FORWARD IN THESE UNCERTAIN TIMES? AND ... lF DR FAUCI WAS COMFORTABLE WITH IT, A COUPLE OF QUESTIONS ABOUT HIS BASEBALL FANDOM ... WITH ALL THAT'S HAPPENING AROUND US AN D YOUR IMPORT ANT ROL E IN IT , JT MlG HT SEEM TRJTE TO DISCUSS BASEBALL. BUT I KNOW YOU'VE BEEN A YANKEE FAN FOR MORE THAN 70 YEARS. AND I WOULD LIKE TO ASK YOU A FEW BASEBALL QUESTIONS. WHEN AND HOW DID YOUR YANKEE FANDOM BEGIN ? YOU WERE A YOUNGSTER WHE THE YANKEES WON 5 STRAIGHT WORLD SERIES TITLES FROM 1949-1953, THE ONLY TIME THAT'S EVER HAPPENED IN BASEBALL HISTORY . WHAT ARE YOUR MEMORIES OF THOSE YEARS? HOW HAS YOUR BACKGROUND IN SPORTS HELPED YOU IN YOUR ROLE WITH THE NIALD? AND, FINALLY, YOU ' VE SPOKEN ABOU T HOW NEW YORK IS THE EPICENTER OF THE VIRUS. FOR NEW YORKERS WHO ARE LOOKING FOR SOME LIGHT AT THE END OF THE TUNNEL , WHAT WOULD YOU SAY TO THEM? (b)(6) From: Date: To: Subject: Mon, 27 Apr 2020 07:00:08 -0400 Barasch,Kimberly (NIH/NIAID) [CJ Fwd: The global health leaders call, THURSDAY30 April at 14.30 CET FYI Begin forwarded message: Fr om : "RYAN, Michael J." (b)(6J> Date: April 27, 2020 at 5:34:56 AM EDT To: SHOC (b)(6) , Office of the Director-General , "Redfield Rober t R. CDC/OD " (b)(6) (b)(6) (b)(6)David Heymann (bH6l>, "Felicity Harvey (b)(6) "Chris .Elias" (b)(6) (b)(6) , "Fauci, Anthony (NIHINIAID) [E]" (b)(6)"COX,Paul M_ichael" "SCHWARTLANDER, BemhardF." Raman" _________ __,, ------- "GREIN , Thomas" (bH > , (bH6l, "MINHAS , (b)(6J i.....;_ ~= "Conrad, Patricia (NIH/NIA ID) [E]" ------. (bH6J ~, "MAH JOUR, Jaouad" (b)(6J , "FALL, Ibrahima Soce" (b)( , "Thomas R. Friede n" (b)(6) Lynn Bank s (b)(6) , President I Reso lve to Save Live s , "Amadou .SALL" SHORBATI, Farah" "DRURY, Patrick Anthony" -------- , Robynn Leidig (b)(6)> , (b)C6lt> , "Dr VAN KERKHOVE, Maria" (b)(6) (b)(6)"POOLE,Marcia" "GRAAFF, Peter Jan" (b)(6)TarikMohammed -------- (b)(6) Navarro Colorado _____ _, Ryan Morhard_____ Carlos ~ ___, Cb)(6)~ "BRI AN D, Sylvie" Cb>< , "MORGA N, Oliver' , (b)(6) "Harries, Jenny" (b)( , "Awwad , David (NIH/NW D) [C]" Cb)(6), "SIMONSON, Stewal1' CbH6) "SINGER, Peter Alexande r" (b)(6) "Jayat unga, Wikum" (b)(6) "Julie.HALL" -----,, CbH6)>, "KABIR, Sophia" RIOUX CbH6)>, Ame lie (b)( (b)(6) , "SHIN, Young-Soc" (b)(6) Feng Ding (b)(6) ------------ ASMA , Samira" (b)(6) Cc: SHOC , Office of the Dir ector-Genera l , "SCHWARTLAN DER, Bernhard F ." ______ Cb)C6) , "MAHJOUR, Jaouad'' Cb>< , "FAL L, lbrabima Soce" (b)(6) , "GREIN, Thomas" Michael" ___ ..,, "POOLE, Marcia" CbH6) , CbH6) , "MINHAS, Raman" Cb>< , "AL-SHORBAJI, Farah" CbH6) , "DRURY, Patrick Anthony" , "COX, Paul CbH6), (b)(6) , "GRAAFF , Peter Jan" CbH6)>, "Dr VAN ------KERK.HOVE , Maria" Cb> (6) , "KAB IR, Sophia" Cb)< , "FARES, Christine Youssef' Cb)< ------"AYLWA RD , Ray mond Bruce J." (b)(6) , "SMITH, Ian Michael" (b)(6) Subject: The global health leaders call, THURSDAY 30 April at 14.30 CET Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference w ill be hosted on THURSDAY, 30 Apr il at 14:30 CETand Zoom detai ls are copied below . If you experience any technical difficulties joining th is conference call, please contact the WHO HQ EOCoperator at: +4122791 5533 It would be appreciated if you could kindly confirm your participation to Ms Sophia Kabir, email (b)(6); mobile no. (b)(6) The agenda and background documents will be shared ahead of the call. Best, Mike Join Zoom Mee ti ng https:// w ho.zoom .us/j l Cb)(6),Cb)(4~ Meeting ID: (b)(6), (b)(4) Password: H6>,(bH4> Dial by your location +41 43 210 71 08 Switzerland +4143 210 70 42 Switzerland 0 800 561 252 Switzerland Toll-free 0 800 002 622 Switzerland Toll-free +l 253 215 8782 US {Tacoma) +l 213 338 8477 US {Los Angeles) 888 475 4499 USToll-free 877 853 5257 USToll-free +33 7 5678 4048 France +33 1 7095 0350 France 0 800 944 049 France Toll-fr ee 0 800 940 415 France Toll-fr ee Meeting ID: (b)(6) , (b)(4) Find your local number: https://who.zoom.us/u/ae Join by SIP Cb)(6), Cb)(4~@zoomcrc.com I FZfwUgUc Frmn: Date: Fauci,Anthony {NIH/NIAID) [E) Mon, 27 Apr 2020 10:54:50 +0000 Duchin, Jeff RE:High Praise To: Eiubject : Jeff: We ll- deserved recognition of your fine work. Best regards, Tony Keep it up. -----------------=-=--== From: Duchin, Jeff Sen t : Sunday,April 26, 2020 11:58 PM To: Fauci,Anthony (NIH/NIAID) [E] Subject: High Praise (b)(6) -------- CbH6)> Tony - in a recent shoddy "investigative journalism " piece about our work here in Seattle (https://www.seattletimes.com/seattle-news/times-watchdog/why-the-seattle-soundersgame-went-on-desp ite-coronavirus-emergency/) the reporter referred to me as being to the Seattle area what Anthony Fauci would become to the country. So despite the crappy reporting he bestowed upon me the highest of praise and rem inded me again of the incredible service you are doing for our count ry . Hang in there and tak~ care of your self. We need you . Jeff Why the Seatt le Sounders game March 7 went on X despite coronavirus emergency As virus fears grew, public officials and sports execs debated health risks - and PR messages - but let 33,000 into a March 7 Sounders match. At what cost? www.seattletimes.com Jeffrey S. Duchin, MD (he/him) Health Officer and Chief , Communicable Disease Epidemiology & [mmunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave , Suite 1250, Seattle, WA 98104 Tel: (206) 296-4774; Direct E-mail: (b)(6) ,; Fax: Cb)(6) (206) 296-4803 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mo n, 27 Apr 2020 02:47:49 +0000 To: Shapiro, Neil (NIH/OD) [E];Collins, Francis (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Johnson, Alfred (NIH/OD) [El;Hallett, Adrien ne (NIH/OD ) [El Subje ct: RE: NIAID fac ilities in the CARESAct spend plan I suggest tha t _________________________ Cb _H_6) From: Shapiro, Neil (NIH/OD) (El (b)(6)> Date: Sunday, April 26 , 2020 10:32 PM To: Collins, Francis (NIH/OD) [El ______ (b ""'),..., (6) = >; Tabak, Lawrence (NIH/OD) (El (b)(6)>; Fauci, Anthony (NIH/NIAID) (E) (b)( ; Johnson, Alfred ":".":"~'.:"":"':-:":':'-:=====-..;,_~= (NIH/OD) [E) (b)(6)>; Hallett, Adrienne (NIH/OD) [E) < CbH > Subject: NIAID facilities in the CARESAct spend plan Importance: High Francis and Tony, I have been working to get OMB/ASFR clearance for the 3rd Supplemental spend plan, and have encountered a hitch with 0MB concerning the VRC/RML proposal. They say they (b)(5J ---------------Neil (b)(5) Thanks, Fauci, Anthony (NIH/N IAID) [El Mo n, 27 Apr 2020 02:46:32 +0000 Collins, Francis (NIH/OD) [El RE: New England Journal of Medicine 20-13479 From: Date: To: Subject: Yes, please. From: Collins, Francis (NIH/OD) [E] ------Date: Sunday, April 26, 2020 10:32 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~ -------- (b)( '> = (b)(6)> Subject: FW: New England Journal of Medicine 20-13479 Want me to call CbH6)? From: Corey MD, Larry (b)( > Date: Sunday, April 26, 2020 1:44 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Fauci, Anthony (NIH/NIAID) [El CbH6);Mascola, John (NIH/YRC) [El (b)(6).> Subject: RE: New England Journal of Medicine 20-13479 -------- I think it would be very helpful , I see no downside .. ------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 26, 2020 6:38 AM To: Fauci, Anthony (NIH/NIAID) [El------= (b) ""'(6) = >; Mascola, John (NIH/VRC) [El (b)(6); Corey MD, Larry (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------- If it would be helpful, I'd be glad t o do the outreach to Holden Thorp- Tony and I can discuss. Francis From: Fauci, Anthony (NIH/NIAID) [El< (b)(6)> Date: Sunday, April 26, 2020 8 :37 AM To: Mascola, John (NIH/VRC) [E] (b)(6)>; Corey MD, Larry Collins, Francis (NIH/OD) [El (b)(6)> Subject: RE: New England Journal of Medicine 20-13479 --------,; All good options. Let us go with Science first. =, If they do not want it , I am certain that Science Translational Medicine will take it. I will discuss with Francis and John. From: Mascola, John (NIH/VRC) [E] (b)(6)> Date: Saturday, Apr il 25, 2020 5:59 PM To: Corey MD, Larry (b)(6)>; Collins, Francis (NIH/OD) [El -------- (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: New England Journal of Med icine 20-13479 In looking at NEJM, they have had 4 COIVD-19 perspect ives in last 6 weeks, and they may have impacted their thinking. Agree with talking to editors . If inte rest in Science or Nature, suggestions below. Priscilla Kelly, editor at science emai led me Science, we could check with her. If Nature, Ursula Weiss. a w hile about their interest in papers. So if inte rest in John From: Corey MD, Larry (b)( Date: Saturday, Apr il 25, 2020 5:50 PM To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] -------= > = ~======~= --------- (b)(6) >; Mascola, John (NIH/VRC) [E] Subject: Re: New England Journal of Med icine 20-13479 You and Tony decide . Science or Nature accomplish the same but it seems we need a discussion with the editor first to explain the importance of the manuscript. Sent from my iPhone On Apr 25, 2020, at 2:18 PM, Collins, Francis (NIH/OD) [El ------- (b)(6)> wrote: Very surprised. Do you want me to push back? Francis From: Corey MD, Larry (b)( > Date: Saturday, April 25, 2020 3:55 PM To: Fauci, Anthony (NIH/N IAID) [E] ______ ------~= Cb _H_6J>;Mascola, John (NIH/VRC) [E] (b)(6) Cc: Collins, Francis (NIH/OD) [E] (b)(6J: Subje ct: RE: New England Journal of Medic ine 20-13479 A do have to say I am surprised . but ok -------- (b) (6)> From: Fauci, Anthony (NIH/N IAID) [E] Date: Saturday, April 25, 2020 12:53 PM To: Corey MD, Larry (b)(6)>; Mascola, John (NIH/VRC) [El (b) ~ > Cc: Collins, Francis (NIH/OD) [El (b)(6) Subject: Fwd: New England Journal of Med icine 20-13479 Let us discuss next steps Begin forwarded message: From: New England Journal of Medi cine Date: April 25, 2020 at 12:31:26 PM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Subject: New England Journal of Medicine 20-13479 Reply-To: " editorial@nejm.org " Dear Dr. Fauci, I am sorry to info rm you that your submission , "A Strategic Approach to Successful COVID-19 Vaccine Development," has not been accepted for publication in the Journa l. It was evaluated by members of our editorial staff. After considering its focus, content, and interest, we made the editorial decision not to consider your submission further . We are informing you of this promptly so that you can subm it it elsewhere. Thank you for the opport unity to consider your submission. Sincerely yours, Eric Rubin, M .D., Ph.D. Editor-in Chief New England Journal of Medicine 10 Shattuck Street Boston, MA 02115 (617) 734-9800 Fax: (617) 739-9864 http://www.nejm.org From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 27 Apr 2020 00:48:28 +0000 Adrian Hill Hildegund Ertl;Sarah Gilbert;Redfield, Robert R. (CDC/OD) RE:COVID-19 vaccine Adrian: Thank you for you note. Sorry that I took a few days to get back to you, but I have been swamped. It is good to know of your work on t he chimpanzee adenoviral vectors . The biosafety classification of viral vectors in the U.S. is within the purview of the CDC, and so I have copied CDC Director Bob Redfield on this e- mail. He would be able to point you in the right direction. Best regards, Tony From: Adrian Hill Date: Monday, April 20, 2020 6:16 PM (b)(6) -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hildegund Ertl (b)(6); Sarah Gilbert Subject: FW: COVID-19 vaccine _________ .. (b)(6)> (b)( > Dear Dr Fauci (b)(4) Thank you for your consideration of th is at an exceptionally busy time . Yours sincerely Adrian Hill Professor Adrian V. S. Hill Director, The Jenner Institute Nuffield Department of Medicine University of Oxford Old Road Campus Research Building Oxford OX3 7DQ Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:45:21 +0000 Marston, Hilary (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El FW: 260 County Models of COVID-19 Outbreaks across the US From: Date: To: Cc: Subject: Please see me or give me a call about this. From: Rubin, David M (b)(6)> Date: Tuesday, April 21, 2020 9 :04 PM To: Fauci, Anthony {NIH/NIAID) [E]_______ Cc: Offit, Paul Thank s. (b """' ),,.., (6>: => ---------- (b)(6); Tasian, Gregory E (b)(6J>; Huang, Jing (b)( 6) > Subject: 260 County Models of COVID-19 Outbreaks across the US Hi Dr. Fauci, Jon Yewdell suggested I contact you directly to expedite a briefing on the new county-level models t hat our center, Policylab, at CHOP, will be releasing tomorrow. He shared with us your note below about including Ambassador Birx and Bob Redfield as well. We'd be happy to do so, and had been in touch with Ambassador Birx last week. We have also stayed in contact with the analytics team led by Irum Zaidi and Chuck Vitek. I am also taske d to Governor Wolfs crisis team in Pennsylvania and shared the data with the Governor today. Let us know next steps for arrang ing a video conference. Will arrange our schedule at your convenience. Will have Ors. Paul Offit, Greg Tasian, and Jing Huang join from our team . Best, Dave David Rubin, MD MSCE Director of Population Health Inno vation Dir ector of Policy Lab Children's Hospital of Philadelphia Office: (b) (6) Cell: (b) (6) www.policvlab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Pro fessor of Pediatri cs Perelman School of Medicine University of Pennsylvania From: "Yewdell, Jon (NIH/NIAID) [E]" Date: Tue sday, April 21, 2020 at 8:55 --------PM To: "Rubin, David M" cc: Paul Offit ----!:====~~--- --------- (b)( (b)(6)> · CbH6)> Subject: David, At this point, I think it is best to contact Tony directly. He's at (b)(6) Good luck! JOll Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NIAID, NIH Truth ·wins: A Practical Guide to Succeeding in Bion1edical Research free eBook download of my book Link to Ohio State Science Sunday video on scientific method From: Rubin, David M -------- (b)(6) Date: Tuesday, April 21, 2020 8:43 PM Jon (NIH/NIAID) [E] --------=(b=)(=6) Cc: Offit, Paul (b)(6) Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy To: Yewdell, Hi Jon, Paul forwarded me your email back to him. Our team would be happy to present to him, Ambassador Birx, and Bob Redfield . We have shared t he models with Governor Wolf in Pennsylvania today, and they are informing strategy here . The 260 county models will post to our Policylab website tomorrow . Of note, Paul and I had spoken to Ambassador Birx in the last couple of weeks, and we have been in contact with Irum Zaidi, Chuck Vitek, and the analytics team. Let us know how would be best to set up a group webinar to present the information. Or feel free to connect us directly with their schedulers. Think the models illustrate the low margin of error in the large cities for resurgence risk, even as other less densely populated counties may be tolerant to reopening strategies. Dave David Rubin, MD MSCE Director of Population Health Innovation Director of PolicyLab Childr e n's Hospital of Philad elphia Office: (b) (6) Cell: (b) (6) www.uo1icylah.cho_p.eduI @PolicyLahCHOP Children's Hospital of Philadelphia Professor of Pediatric s Perelman School of Medicine University of Pennsylvania ~V"'-' Per elman Schoo l of rvtt.-cli cini.: l}l\l\ ► 1\1 'r From: Paul Offit 1/r1,,,10,, • CbH6)> Date: Tuesday, April 21, 2020 at 5:46 PM To: "Rubin, David M" Cb)(6) Subject: Fw: Heads up from Paul Offit and David Rubin on po licy memorandum to reopen economy Tony has seen our memo. His response is below. (b)( > From: Yewdell, Jon (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 5:45 PM To: Offit, Paul Subject: FW: Heads up from Paul Offit and David Rubin on policy memorandum to reopen economy --------- Tony neve r ceases to amaze me . ... See immediate reply below Jonathan Yewdell MD, PhD Chief, Cellular Biology Section Laboratory of Viral Diseases NTAID, NTH Truth Wins: A Practical Guide to Succeeding in Biomedical Research free eBook download of my book Link to Ohio State Science Sundav video on scientific 1nethod From: Fauci, Anthony (NIH/NIAID) [E] Cb> <6l > Date: Tuesday , Apri l 2 l, 2020 5 :06 PM To: Y ewdell , Jon (NIH/NIA ID) (E] CbH ·> .__...,,.,..= Cc: Shaffer, Meredith (NIH/NIAID ) [E] CbH ; Conrad, Patricia (NIH/NIAI D) [E] CbH >; Barasch, Kimberly (NIH/NIA ID) [C] ---------=-~ (b)(6) Subject: RE: Heads up from Pau l Offit and David Rubin on policy memorandum to reopen economy Jon: Thanks for the note. It would be even better if they could p resen t no t only to me, but to Deb Birx and Bod Redfi eld. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 (b)(6) E-mail -------- The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Yewdell, Jon (NIH/NIAID) (E] (b)(6) Date: Tuesday, Apri l 21, 2020 4:29 PM = To: Fauci , Anthony (N IH/N[A[D) [E] -------~ (b)( 6) ..._~~ Cc: Shaffer, Meredith (NIH/NIAID) [E] (b)(6) Subject: Heads up from Paul Offit and David Rubin on policy memorandum to reopen econom y Tony, Paul and David asked me to pass this on to you. Forwarded message from David: "I think the time has come , with our models on 260 counties across the country relea sing in the next 48 hour s, to offer Tony Fauci, and potent ially other ta sk force member s, a previ ew of the work. Our models have incorporated local area differences due to weather, population and social distanc ing. Th ey reveal that the large, densely popula ted cities will stru ggle to re-op en , and are not well aided by weather effect s given their density. However, in less densely popula ted areas, in which case count s are lower , wea ther has been a mitigating factor. These latter countie s may have better success when they re-open assuming they are smart about workplace safety and have testing and surveillance strategies in place" Dave David Rubin, MD MSCE Director of Pop ulation Healt h Inn ovation Director of Policy Lab Children 's Hospital of Philad elphia Office: (b) (6) Cell: (b)(6) m,vw.policylab.chop.edu I @PolicyLabCHOP Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine University of Pennsylvania From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 27 Apr 2020 00:43:24 +0000 Young, Neal S {NIH/NHLBI) [E) RE:Lambris Thanks, Neal. Best regards, Tony From: Young, Neal S {NIH/NHLBI) [E]_______ Se nt: Wednesday, April 22, 2020 8:07 AM To: Fauci, Anthony (NIH/NIAID) [E) ------= Subject: FW: Lambris Cb> _<_.> (b)""'(6J = > Dear Tony 'Forwarding to you at the request of two colleagues, experts in anti -complemen t therapies . Thanks, and 'stay health y. Neal CbH6)> Date: Tuesday, Apri l 21, 2020 at 2:43 PM To: Skype CbH6) (b)(6) Cc: Antonio M Risitano -------Subj e ct : Lambris From: "John D. Lambris" Hi Neal, I hope all is well and you are staying healthy . (b)(4) Could you please bring us in contact with Antony Fauci t o see if he can help our program? All the best and Stay Healthy John From: Date: To: Subject: Inhibitors Attachm e nts : Fauci, Anthony {NIH/NIAID) [E] Mon, 27 Apr 2020 00:42:34 +0000 Lerner, Andrea {NIH/NIAID) [E] FW: Update: Inhibit cytokine storm in COVID-19 patients by Proteasome (b) (4) Please respond to th is person. Thanks. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 22, 2020 9:41 AM To: Coomes, Stephani e (NIH/N IAID) [E] _________ (b ::-; ),.,. (6) = >; Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Cc: (b)( Kircheis Dr. Ralf Subject: Update : Inhib it cytokine storm in COVID-19 patients by Proteasome Inhibitors Importance: High Dear Dr. Fauci, dear Dr. Coomes, thank you for your reply from 13. April with the notice that the information has been shared with NIAID's COVID-19 research team . Has the project already been initia lly evaluated by the team? Are there any questions or need for additional information? • I have summed up the relevant data regarding the use of proteasome inhibitors for treatment of COVID-19 patients with acute lung and systemic organ failure in a position paper, please find a Preview draft attached. • With regard to currently ongoing t rials with monoclonal antibodies against the IL-6 receptor, i.e. tocilizumab or sarilumab: These approaches go into the same direction as the present suggestion, however, inhibit ion of NF-KB by proteasome inhibitors could provide the unique potential to inhib it the release of multiple cytokines simultaneously, in particular strongly proinflammatory cytokines including IL- 1, IL-6, T N Fa and chemokines, such as MIP-1 and CXCL1. • This simultaneous inhibition of multiple cytokines/chemok ine seems to be advantege aus compar ed to single ta rget approaches {as wit h the mAb) to compensate fo r redundant and synergistic effects of multiple cytokines released during highly pathogenic CoV o r HSNl infection . Looking forward to hearing from you. Kind regards, Ralf Mit freundlichen GrU~en / Kind regards Dr. Ralf Kircheis Director R&D Research& Development Mail: RKircheis@syntacoll.de Phone:+49 9441 686048 s~ntacoll <:;ynt:ittnll hmhH, Onn::u,c:tr;ic;c;.p ?4, n-CJ~~? Tel: +499441 / 68 60 Hande lsregister: o, Fax: Amtsgericht <:;(4;\l ;;:1 rl l1tn.::u.1 +49 9441 / 68 60 30 Regensburg· HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhrerin: Dr. Alexandra Dietr ich Unsere Hinweise zum Datenschutz, lnsbesondere zu den Ihnen zustehenden Rechten, flnden Sle unte r www .syntacoll.de/ datenschutz Von: Coomes, Stephanie (NIH/NIAID) [E] Gesendet: Montag, 13. Apri l 2020 02:37 (b)(6) An: Kircheis Dr. Ralf Betreff: RE:Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Dear Dr. Kircheis, Thank you for your recent email to Dr. Anthony Fauci. Your message was forwarded to the Division of Microbiology and Infectious Diseases (DMID) at the Nat ional Institute of Allergy and Infectious Diseases (NIAID). As a member of DMID 's Office of Scientific Coo rdin ation and Program Operations, I am pleased to respond. I want to thank you for reaching out to share this informat ion and let you know that your message has been shared with NIAi D's COVID-19 research team . Sincerely, Stephanie Stephanie M. Coomes, Ph.D. Health Scientist Administrator Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health 5601 Fishers Lane, Room 7G68 Rockville. MD 20892 (b)(6) V Disclaimer: The informat ion in this email and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the originally intended recipient. If you have received this email in error, please inform the sender and delete it from your mailbox or any other storage devices. The National Institu te of Allergy and Infectious Diseasesshall not accept liability for any statements made that are the sender's own and not expressly made on behalf of NIAID by one of its representatives. From: Kircheis Dr. Ralf Date: Wednesday, Apr il 8, 2020 2:49 AM ------ == To: Fauci, Ant hony (NIH/NIAID ) [El (bH >; Billet, Courtney (NIH/N IAID) [El ______ (b _)_C6) _ >; NIAID Ocpostoffice (NIH/NIAID) <0CPOSTOFFICE@niaid .nih.gov> Cc: Fischer, Elizabeth (NIH/NIA ID) [El (b)( >; Foster, Erin (NIH/NIAID) [El (b)( >; Foster, Sarah (NIH/NIAID) [El (b)(6); Vasilenko, Olga (NIH/NIAID ) [El (b)(6>:>; Vasquez, Aureli o (NIH/NIAID) [El ________ (b _)_C6) _,; Vostal, Alexander (NIH/VRC) [Fl (b)( >; VazquezMa ldonado , Nancy (NIH/NIAID ) [El (b)(6); Austi n, James (NIH/NIAID) [El 4 (b)( ·>; Agulto , Liane (NIH/NIAID) [E] (b)(6)>; Deckhut, Alison (NIH/NIAID ) [E] (b)(6)>; Kircheis Dr. Ralf Subject: WG: Inhibit cytokine storm in COVID-19 patients by Velcade Bortezomib Importance: High Inhibition of cytokine storm in COVID-19 patients with acute respiratory distress syndrom by PROTEASOME INHIBITORS e.g. Velcade {Bortezomib} Dear Dr. Fauci, dear Madams/Sirs, I want to bring to your attension some potentially important experimental data and a new proposal for treatment of COVID-19 patients with acute respiratory distress syndrome and organ failure . Sorry for the broad distribution but I wanted to make sure tha t my message reaches you. Similarly as has been described earlier for SARS-CoV, MERS-CoV (Channappanavar& Perlman, 2017) , H5Nl and some heavy HlNl Influ enza A infections, also COVID-19 patients have been reported to show significantly increased systemic cytok ine release (i.e. cytoki ne storm), particularly those patients with lung failure or system ic organ failure (Chao/in Huang et al. Lance t vol 395, 2020, ref 1). Previous studies at VirologikGmbH, Erlangen, Germany, in colabo ration with the Friedrich-Loefflerlnstitut, Tuebingen,Germany have shown, that HSNl (or alternatively LPS) -induced Cytokinestorm in vivo can be inhibited by applicationof ProteasomeInhibitors (E. Haasbach et al, Antivira l Res. 91, 2011, ref. 2), via the inhibition of translocationofthe NF-icBtranscriptionfactor to the nucleus (see Fig. below ). The mechanism of NF-KB inhibition by proteasome inhibitors is well described, and works via the inhibition of t he protea soma I degradation of t he cytosolic inhibitor IKB, this way keeping NF-KB bound in the cytosol and there by inh ibit ing t he otherwi se induc ed (by cyto kine or LPS- or RNA vi rus) translocat ion of NF-KB to the nucleus where it would initiate the transcr ipt ion of many cytok ines. This effect of proteasome inh ibitors seems to wo rk in most cell ty pes, we could demonstrate this effect in several different cell types (including macrophages) after stimulation w ith TN Fa in vitro and in HSNl (or LPS)treated mice in vivo (see manuscript and Figs. attached) . Inhibition of NF-KBby proteasome inhibitorsprovidesthe unique potential to inhibit the release of many cytokinessimultaneously, in partic ular strongly pro inflammatory cytokines IL-lex.,IL-6,TNFa.,MIP1fL.) (w hereas some other cytokines involved in ant ivir al immune response, such as IFNy probably seem to be not/less affected (because of diffe rent transcription pathway) . Importantly, beside t he anti-inflammatory activity, prot easome inhibitors showed also significant antifibrot ic activity (Lueftenegger et al., manuscript and figs attached) , which may be also important in the treatment of COVID-19 patients with heavy lung disease. Furthermore, there have been several publications showing tha t in particular early phases of the replication cycle of Corona virus seem to be dependent on interaction with the ubiquitin-proteasomal system (UPS) of the host cell, and were effectively inhibited by selective 20S proteasome inhibitors (such as Velcade) (Wang et al. Viro logy J 2010 , 7:99 (ref . 3}; M. Raaben et al. J. Virology, 84(15), 2010, ref. 4). There are several registered proteasome inhibito rs (Bortezomib (Velcade Gt ) e.g. produced by Mill ennium Pharmaceuticals (i.e Takeda Oncology); Carfilzomib (Kyprolis®), lxazomib (Ninlaro ®)) for treatment of multiple myeloma and Mantel cell lymphoma, i.e. there are registered drugs with well known side effects available to be tested in small clinical studies for evaluation of their therapeutic efficacy in COVID-19 patients with heavy lung disease and other organ failure. Noteworthy: in contrast to the chronical oncological indications where up to 8 trea t ment cycles (and sometimes even more) are applied, it seems plausible that just one or two treatment cycles of proteasome inhibitors might be sufficient to downregulate the cytok ine storm in COVID-19 patients, which would be associated also with much lower side effects. Early first experience on efficacy could be gained from compassionate use applications in heavily ill COVID-19 patients very quick ly. Beside the registered application forms, i.e. infusions, probab ly also inhalative application should be tested as well, because it may be better suited to reach the respecti ve target cells in the lung, i.e. alveolar epithelial cell and alveolar macrophages. There are multiple inhalative devices available, e.g. the Handyhaler by Boehringer lngelheim used for Spiriva (for COPD treatment). Alt hough t here are still many open questions, the potential to control the cytokine storm-induced heavy lung and other organ failure by using already registered drugs, ie. proteasome inhibitors may be a real chance to get an additional treatment option , hopefully decreasing the cases necessary for artificial aeration. Pleaseforward this mail to the colleages you consider relevant for evaluation, discussion and consideration for your clinical strategy for COVID- 19. Please let me know if additional info rmations are necessary. To my person: I have MD PhD degree and have many years experience in pharmaceutical development (Boehringer lngelheim ), Biotech (lgeneon, Aphton, Virologik GmbH) (for reference see also PubMed Kircheis r) currently leading R&D activities at Syntacoll (part of lnnocoll). I am providing this information personally in order to help to find a t reat ment for COVID-19 patients . Looking forward to getting feedback from you, With kind regards, Ralf Kircheis (MD PhD) (b)(6) rkircheis@synt acoll.de (b)(6) Pis inhibit TNFa. Induced nuclear NFicB translocation control • PI inhibi t TNF« induced nuclear Nft.B cranslocation in a variety of cells, Including tumor cells, stellate ceUs and macrophages @ VIRO LoGI K Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13. Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses. Haasbach E1, Pauli EK, Sprange r R, Mitzner D, Schubert U, Kircheis R, Planz 0. Author information Abstract The appearance of highly pathogenic avian influenza A viruses of the H5N1 subtype being able to infect humans and the 2009 H1N1 pandemic reveals the urgent need for new and efficient countermeasures against these viruses . The long-term efficacy of current antivirals is often limited , because of the emergence of drug-resistant virus mutants. A growing understanding of the virus-host interaction raises the possibility to explore alternative targets involved in the viral replication. In the present study we show that the proteasome inhibitor VL-01 leads to reduction of influenza virus replication in human lung adenocarcinoma epithelial cells (A549) as demonstrated with three different influenza virus strains, A/Puerto Rico/8/34 (H1 N1) (EC50 value of 1.7 µM}, A/Regensburg/O6/09 (H1 N1v) (ECSOvalue of 2.4 µM) and A/Mallard/Bavaria/1 /2006 (H5N1) (EC50 value of 0.8 µM). In in vivo experiments we could demonstrate that VL-01-aerosol-treatment of BALB/c mice with 14.1 mg/kg results in no toxic side effects, reduced progeny virus titers in the lung (1.1 ± 0.3 log 10 pfu) and enhanced survival of mice after infection with a 5-fold MLD50 of the human influenza A virus strain A/Puerto Rico/8/34 (H1 N1) up to 50%. Furthermore, treatmen t of mice with VL-01 reduced the cytokine release of IL-a/~, IL-6, MIP-1 ~. RANTES and TNF-a induced by LPS or highly pathogen avian HSN1 influenza A virus. The present data demonstrates an antiviral effect of VL-01 in vitro and in vivo and the ability to reduce influenza virus induced cytokines and chemokines. Copyright© 2011 Elsevier B.V. All rights reserved. PMID:21777621 DOl :10.1016/j.antiviral.2011.07.006 [Indexed for MEDLINE Mit freundlichen Grul?,en/ Kind regards Dr. Ralf Kircheis Director R&D Research & Deve lopment Mail: RKircheis@syn tacoll.de Phone: +49 9441 686048 s~ntocoll Syntaco ll GmbH, Donaustrasse 24 , D-93342 Saal a . d. Donau Tel: + 49 9441 / 68 60 o, Fax: + 4 9 9441 / 68 60 30 Hande lsregister: Am t sgeri cht Regensburg • HRB 1612 USt· ldNr. DE 128580796 Geschaftsfuhre rin: Dr. Alexand ra Dietr ich Unsere Hinweose zum Datenschutz, insbesondere zu den Ih nen zustehenden Rechten, fi nden Sie unte r wwwsvotacoll de/datenscbut2 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 27 Apr 2020 00:40:50 +0000 Xizhong, Cui (NIH/CC/CCMD) [El RE:remdesivir and Present's wor ds on disinfectant Brian: Thank you for your note. (b) (5) Best regards, Tony --------------=-=--== -------- (b)( > From: Xizhong, Cui (NIH/CC/CCM D) [E] Date: Sunday, April 26, 2020 8:36 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: remdesivir and Present's words on disinfectan t Dear Dr. Fauci, I am an investigator in CCMD, CC, National Institutes of Health, I am studying coronav irus infection in animal models on preclinical treatment. I was a doctor when I was in China, now I am just a preclinical invest igator on infectious diseases. (b) (5) (b) (6), (b) (5) Best wish to you and be safe. Thanks your efforts to all Americans!! Brian X. Cui, MD, Ph.D Critical Care Medcicine Department Clinical Center National Institutes of Health Phone: (b)( From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [EJ Sun, 26 Apr 2020 23 :13:59 +0000 Folkers, Greg (NIH/ NIAID) [E) Re: Keynote Spea~er- Keystone Vac:cinology eSymposia (direct ions to record & upload t alk) Attachment s: image00 l. png, image002.png, image003.png, image004.png, imag e00S.png Agree. On Apr 26, 2020, at 6:38 PM, Folkers, Greg (NIH/NIAID) [E] (b) (6) wrot e : I think Hilary is closest to this and shou ld get the assignm ent From: Fauci, Anthony {NIH/N IAID) (E] (b)(6)> Date: Sunday, Apr il 26, 2020 5:12 PM To: NIAID OD AM Subject: FW : Keynote Speaker- Keystone Vaccinology eSymposia (directions to record & upload tal k) Greg and t eam: Let us di scuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. Fro m : Kristina Horton Date: Friday, April 24, 2020 4:06 PM To: Fauci, Anthony (NIH/N IAID) [El .--------,.(b._.., )(= > (b)( > Cc: rino.r.rappuol i@gsk.com; Conrad, Patricia (NIH/NIAID) [El Subjec t: Keynote Speaker- Keystone Vaccinology eSymposi a (directions to record & upload ---------- talk) Greeti ngs Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia: Vaccinology in the Age of Pandemics : Strategies Against COVID19 & Other Global Thr eats , a virtual conference which will be held on, Monday , June 15 and Tuesday, June 16, 2020 . Understand ing how busy you are right now, we would like to make this process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we w ill work with your schedule . Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccino logy: COVID-19 Emergency and Conside rations for the Next Decade o Please rev iew your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk reco rding , by Monday, May .1.!l.Click here to learn more about recording your presentation . Our media team can assist you with record ing on your personal computer. • Similar to the face -to-face conference , we env ision approx imately 50-60 minutes for the keynote lecture . For questions about the scientific progra mming of this meeting, please contact Dr. Rappuoli at rino.r.rappuoli@gsk .com and I will serve as the administ rative/logistics contact at KristinaH@KeystoneSymposia.org. Best, Kristina Kristina H. Richardson, MS Scienti fi c Advisory Board Coord inator Administrative Assistant: CSO& Global Developmen t + (b)( 6) I kristinah@keystonesymposia.org POBox 1630 I Silverthorne I CO80498 I USA (regular mail only) 160 USHighway 61 Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800 .253.0685 I www.keystonesymposia.o rg Visit virtual.keystonesymposia.org to view our digital content . KEYSTONE'" SYMPOSIA' o n M o le c ul a r a nd Ce llul a r Bi ology Accc/crari ng Life Scie nce Discovery DIVERS I TY IN THE SCIENTIFIC 0 0 0 WORKFORCE KEYS IONE11A SYMPOS~ 011Molecular an V1cellular JloJ01y Aee.,...IAMM• •IY■lllff DIMM._, •• 1NI KIIITIPIC ·••11,oac■ From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sun, 26 Apr 2020 23 :13:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: Attachments : Gayle__ Re: Thank you , and ... image002. png Cb _ >_<6) _ and so I would like to do it if they clear it On Apr 26, 2020, at 7 :08 PM , Conrad, Patri cia (NIH/NIAID) [E] Cb)(6) wrote: You sent this to me on Friday but we have not had a chance to discuss. (bXS)- l'U Please advise if you want to do this - again, adding others here as well.. -p From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, April 26, 2020 5:44 PM To: Folkers, Greg (NIH/NIA ID) [El [El CbH6)> ------ (b)(6) == (b)( >; Conrad, Patricia (NIH/NIAID) Cc: Barasch, Kimberly (NIH/N IAID) [C) (b)(6) Subject: FW: Thank you, and ... Have we discussed thi s already? Gayle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 CbH6J Phone : Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives . From: Gayle Smith Date: Thursday, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Tom Hart Subje ct : Thank you, and ... ------= --------- ""7 (b)(6) :, Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now more than ever. As an American , a former colleague, a long-time admirer and student of your wisdom -thank you . We are all safer because of you, and t he world will be a better place because of you . Again. As you know, I am now leading the ONE Campaign. We've been quite active w ith the ONEWorld Campaign, dedicated to the fight against this newest virus, and focused on Afr ica. We've made some progress on debt, and next up is a foc us on ensuring that a vaccine, when it comes, is available to everyone. One of the things we want to do is educate people, in all of the places we work. It won 't surprise you that of particular urgency amongst our partners in Afr ica is that facts and information get to people across the continent, but we also know t hat more facts are needed everywhere. So next month we are going to launch #PassTheMic, where every day for 19 days we willask a celebrity to turn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about t he critical elements needed to flatten the curve and slow t he spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can illustrate the imp act COVID-19 will have across Africa and what that means for the rest of the world . We know artists wan t to be helpful right now, but that it is hard to know what to do. And we know there are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and until it is beaten everywhere we are not in the clear. We need a global response plan and we need it now. By turning over th eir platforms for the day, celebrity influencers will be donat ing one of their biggest assets - their followers - to YOU, giving you the platfo rm you need (and we all need) to tell the world why a global response is cri tical. Because none of us are safe unt il all of us are safe. We will work with each expert/celebrity pair to personalize the content to our and our celebrity partners' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with. We are now confirming our talent part ners, and so far are getting a terrific response . We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be maximal. I'm attaching more information about the campaign. Please let me know what you think and if you have questions. Ideally we would like to get th is off the ground in early May, so are hoping to conf irm folks by April 28th at the latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle I President & Chief Executive I Twitter I Facebook I lnstagram Gayle Smith ONE.ORG Officer I ------- (b)(6) ONE is a global movement campaigning to end extreme poverty and preventable disease by 2030 so that everyo ne, everywhere can lead a life of dignity and opportunity . From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :50:57 +0000 Broas, Timothy Grady , Christine (NIH/CC/BEP) [El RE:Greeti ngs Tim: Thank you for your kind note . It was great to hear from you. I hope tha t all is well with you and your family and that we get a chance to reOconnect when the situation begins to return to some form of normal ity .. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Broas, Timothy Date: Thursday, April 23, 2020 10 :26 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Greetings ------- == (b)(6) Dear Tony: It's been a long time. Honestl y, I can't remembe r when we last saw each other. I recall that wonderful day we went to the Nats game together, a lthough I cannot remembe r who else came with us. And of course I will always remember when you came to my Partners in Health fund raiser and introduced Paul Farmer. I will never forget yours eech (and neither will Paul!). Ooce oo~ I apologize for dropping out of touch . Those events were so many yea rs ago, (b) (6) no? So much has happened and changed since then , and now, seeing you and listening to your wise words and advice every day, I am reminded that we need to reconnect, when it's safe and you have time . We have so much to catch up on! I have been meaning to write to you or call you , but I had misplaced your email address and phone numbers. I hope this address works and this message reaches you . Meantime, thank you for your service to our country , indeed the world . You have been a solid, wise, steady voice, Tony , and , despite all the naysayers and fools on social media , you have earned the respect of billions of people. I am very proud of you , and am humbled and honored that I can call you my friend . I hope you and your family are well, and staying safe . The Broas family is doing well, thanks in no small part to your dai ly advice and objective analysis . T hank you! Please let me know if there is anyth ing I can do for you or your family. Looking forward to seeing you on the other side of this, and having a good catch up. Who knows, maybe at a Nats game? Best regards, Tim BRYAN AMBASSADOR(RET) TIMOTHY M. BROAS timothy .broas@bclplaw.com CAVE LEIGHTONnr11~~pr= +1 202 sos611s M: PAISNER ul!,! ---- (b)(6) BRYAN CAVELEIGHTON PAISNERLLP. 1155 F Street NW, Washington, DC 20004-1357 bclplaw.com COVID-19 / CORONAVIRUS RESOURCES ► This electronic messageis from a law firm. It may containconfidential or privileged information. If you received this transmissionin error, please reply to the senderto adviseof the error and delete this transmission and any attachments. We may monitor and recordelectronic communicationsin accordancewith applicable laws and regulations. Whereappropriatewe may also sharecertain information you give us with our other offices (including in otller countries) and select third parties. For further information (includingdetails of your privacy rights and how to exercisethem), see our updatedPrivacyNoticeat www.bclplaw.com. From: Date: To: Cc: Subjec t : Att achment s: Fauci, Anthony (NIH/N IAID) [El Sun, 26 Apr 2020 21:44:20 +0000 Greg Folkers Cb H 6);Conrad, Patricia (NIH/NIAID) [El Barasch, Kimberly (NIH/NIAID) [Cl FW: Thank you, and ... PasstheM ic Expert Outreach.pdf Have we discussed thi s already? Gayle -------- (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail=--__,. _. _, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gayle Smith Date: Thursd ay, April 23, 2020 1:48 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Tom Hart Subject: Than k you, and ... ---------,~ --------(b)(6) Dear Tony, I have always felt reassured when the good Dr. Fauci speaks, and now mo re than ever. As an American, a former colleague, a long-t ime admirer and student of your w isdom - t hank you . We are all safer because of you, and the world will be a better place because of you . Again. As you know, I am now leading the ONECampaign. We've been qu ite active with the ONEWorld Campaign, dedicated to the fight against this newest v irus, and focused on Afr ica. We've made some progress on debt, and next up is a focus on ensuring that a vaccine, when it comes, is available to everyone . One of the things we want to do is educate people, in all of the places we work . It won't surpr ise you t hat of particular urgency amongst our partners in Afr ica is that facts and informat ion get to people across the cont inent, but we also know that more facts are needed everywhere . So next month we are going to launch #PassTheMic, where every day for 19 days we w ill ask a celebrity to t urn his or her social media channels over to an expert on COVID-19 for one day. So Julia Roberts might turn her Twitter account to you to talk about the crit ical elements needed to flatten the curve and slow the spread. Or Idris Elba could give up his lnstagram to the head of the African CDCso that he can ill ustrate the impact COVID-19 will have across Africa and what that means for the rest of the world . We know artists want to be helpful right now, but that it is hard to know what to do. And we know th ere are experts like you out there who have the answers. We've thought about this a lot at ONE and wanted to do something we felt would truly have an impact. As we look ahead we know COVID-19 does not know borders and unt il it is beaten everywhere we are not in the clear. We need a global response plan and we need it now . By turning over their platforms for the day, celebrity inf luencers will be donating one of their biggest assets - their followers - to YOU, giving you the platform you need (and we all need) to tell the world why a global response is crit ical. Because none of us are safe until all of us are safe. We w ill work w ith each expert/celebrity pair to personal ize the content to ou r and our celebrity partners ' audiences - in North Amer ica, Europe and Africa, and help create content that both parties are happy with . We are now confirming our ta lent partners , and so far are getting a terrific response. We know you're a busy man, so we've planned it so that the amount of time on your end would be minimal. But the impact would be ma>:imal. I'm attach ing more informa ti on about the campaign. Please let me know what you t hink and if you have questions. Ideally we would like to get t his off the ground in early May, so are hoping to confirm folks by April 28th at t he latest. Our team will be in touch with your office to follow up. Thanks as always for everything you do. All my best to you, Gayle Gayle Smith I President & Chief Execut ive Officer ONE.ORG I I Twitter I Facebook I lnstagram ------- (b)(6) ONE is a global moveme nt campa igning to end extreme poverty and preventable disease by 2030 so that everyone , everywhere can lead a life of dignity ancl opportunity. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21:36:37 +0000 Lusso, Paolo (NIH/N IAID) [El RE: Potentia l t reatment breakthrough fr om Milan Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)( > From: Lusso, Paolo (NIH/NIAID) [E] Se nt: Sunday, April 26, 2020 5:09 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)(6) Subject: Re: Potent ial t reatment breakthrough from Mi lan -----== .,...:.....:.-!====~~.. Dear Tony : I am trying to reach the Pl of the study, but on a Sunday afternoon/evening I doubt I will be successful. should be able to get mo re information tomorrow morning and pass it on to you, Cliff and Joe Kovacs. Allthe best, Paolo Paolo Lusso, M.D., Ph.D. Chief, Section of Viral Pathogenesis Laboratory of lmmunoregul at ion Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: --==~ (b)(6) (personal) (b;:; H:;;; 6)-:-: (1""""'. ab) Fax: (301) 480-5291 E-mail: -------- (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original int ended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infect ious Diseases(NIAID) shall not accept liability for any statement made th at are the sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: "Fauci, Anthony (NIH/NIAID) [E]" (b)(6) Date: Sunday , Apr il 26, 2020 at 3:47 PM To: "Lusso, Paolo (NIH/NIA ID) [E]" (b)(6) Cc: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: RE: Potential treatment breakthrough from Milan ---------=-~ Thanks, Paolo. (b)( S) (b) (5) Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- From: l usso, Paolo (NIH/NIAID) [E]_______ Date: Sunday, April 26, 2020 12:22 PM Cb _ H_ 6) (b)(6) To: Fauci, Anthony (NIH/NIAID) [E] Subject: Potential treatment breakthrough from Milan ---------- Dear Tony: (b) (5l Congratulations to Brad Pitt for impersonating you! All the best, Paolo From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :17:22 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [Cl FW: Wa shington Post story re: Sammie s finalist s Please set up an interview as requested below. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Davidson, Joe Date: Friday, April 24, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [El -------~~ (b)(6) Cc: (b) (6) Subject: Washington Post story re: Sammies finali sts Hello Tony, Congratu lations on being a Career Achievement finalist for the Samuel J. Heyman Service to Am erica Medals (Sammies ). I'm writing a Federal Insid er column about th e finalists and would like arrange a telephone interview with your for the sto ry. My questions include : Why did you j oin th e federal service? Is ther e one example or anecdote that makes you particularly proud of you work? What do you like most about your job? What do you like least about your job? Why would you recommend, or not, your agency and/or the federal governmen t to those seeking career advice? I know this is an incred ibly bus y time for you. I appreciate that th e life and death issues related to the coronavirus are mor e important than any award. Nonetheless, I hope you can spare 10 or 15 minutes for a telephone interview on Tuesday or Wednesday, April 28 or 29. I can also make other days that week work. Thank you. Best, Joe Joe Davidson, columnist The Washington Post 1301 K Street, NW Washington, DC 20071 202.334 .6415 - work ----- (b) (6) - cell joe.davidson@washpost.com Twitte r : @JoeoavidsonWP Website: wapo.st/JoeDavidson From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:14:32 +0000 Greg Folkers (b)(6) (b)( ;Grady, Christine (NIH/CC/BEP) [E] FW: COG - Helen Branswell/STAT request / challenge studies ------- Please have her speak with Chris and/or Cliff. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . Th e Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 24, 2020 3:04 PM To: NIAID COGCORE Cc: NIAID OD AM Subject: COG - Helen Branswell/STAT request/ challenge studies Helen would like to speak w it h someone (ASF,Cliff , C Grady?) to discuss current thinking here on challenge studies for COVID-19. Not sure of deadl ine. (b)(6) helen .branswell@statnews.com Disclaimer : Any third-party mate rial in thi s email has been shar ed for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor those of NIAID, NCH,HHS, or the U.S. governmen t. From: Date: To: Subject: upload t alk) Attachments : Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21:12:06 +0000 NIAIDODAM FW: Keynot e Speaker- Keystone Vaccino logy eSymposia (direct ions to reco rd & Vaccino logy eSymposia_ DRAFTProgram Description & Schedule.pdf Greg and team: let us discuss. Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Kristina Horton Date: Friday, Apri l 24, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: rino .r.rappuoli@gsk .com; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Speaker- Keystone Vaccinology eSymposia (di rectio ns to reco rd & uplo ad talk) ------- == Greetings Dr. Fauci: Thank you for agreeing to participate as the keynote speaker for the Keystone eSymposia : Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats, a virtual conference which will be held on, Monday, June 15 and Tuesday, June 16, 2020. Understanding how busy you are right now , we would like to make th is process as easy as possible. We are hoping to receive pre-recorded talks by Monday, May 18. Please keep us apprised on your timeline and we will work with your schedule. Here are the details on next steps. Next Steps: • Keynote Talk Title: Transforming Vaccinology : COV ID-19 Emergency and Cons idera tions for the Next Decade o Please review your talk title and return any changes. Changes can be made up to two-weeks prior to the event. • Please follow this link to upload your talk recording, by Monday, May 18. Cl ick here to learn more about recording you r presenta tion . Our media team can assis t you wit h recording on your pers onal compute r. • Sim ilar to the face -to-face confe rence, we envision approximate ly 50-60 minutes for the key note lecture . For quest ions about the scien tific programming of th is meeting , please contact Dr. Rappuo li at rino .r.rappuo li@gsk.com and I will serve as the administrat ive/logistics contact at Kristi naH@KeystoneSympos ia. Org . Best, Kristina Kristina H. Richardson, MS Scientific Advisory Board Coordinat or Administrative Assist ant: CSO& Global Development _,, I kristinah@keystonesymposia.org (b) (6) _____ KEYSTONE ~ SYMPOSIA o n M o l ec ul a r a nd C el l ul a r Bi o l ogy Acc elerating Life Science Discovery DIVERSITY IN THE SCIENTIFIC WORKFORCE POBox1630 I Silverthorne I CO80498 I USA(regular mail only) 160 US Highway6, Ste. 200 I Silverthorne I CO80498 I USA (courier only) 970.262.1230 I 800.253.0685 I www.kevstonesymposia.org Visit virtual.keystonesymposia .orgto view our digital content. oe o o Fauci, Anthony (NIH/NIAID) [E) Sun, 26 Apr 2020 21:11:15 +0000 Hahn, Stephen FW: Thank You! (FDA Submission: EUA200258) From: Date: To: Subject: Attachments : 2AML- COVID-19_ACCREDITATION 1 PAGER.PDF, IMG -20200330 -WA0002 .jpg Steve: They have contacted me, but have you seen this? many that you see. I am sure that it is one of Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Eli J. Safdieh CbH6)> Date: Friday, April 24, 2020 4:12 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) __ ;...;;...;.::======"::::;:;;;-:---Subject: Re: Thank You ! (b)(4 ) ) ---------- Dear Dr. Fauci, Hope all is we ll. Since this crisis has begun, I have been working (b)(4) Best Regards, Eli J. Safdieh From: "Conrad, Patricia (NIH/NIAID ) [E]" _;__ _ _;_;;_;;_.:::=;~c,""------Anth on y (NIH/NIAID) [E]" (b)(6) Date: Thursday , March 19, 2020 at 10:59 AM To: EliSafdieh Subject: RE: Thank You! (bH6)> Dr. Fauci wanted me to thank you for you note. Best regards, Patricia L. Conrad (b)( > on behalf of "Fauci, Public Health Analyst and Special Assistant to the Director National Inst itute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may contain sensi tive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it rrom your mailbox or any otner storage oevices. National 1nslilute or Allergy ano 1nrec11ousDiseases (NIAID ) snau not accep1 liability ror any statement made that are sender's own and not expres sly made on behatr or the NIAID by one or its representatives . From: Eli J. Safdieh ______ _, (b)(6)> Date: Thursday, March 19, 2020 5:13 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You! -------~~ --------- (b)(6) Hi Dr., Hope all is we ll with you and your family. You are a symbo l of integrity, nationalism , human ity, brilliance and perseverance. God bless you in all that you do for our country, fo r human beings and society. We are praying for your success in mitigating and destroying this epidemic! Best Regards, Eli J. Safdieh From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 26 Apr 2020 21:06:30 +0000 Dieffenbach, Carl (NIH/NIAID) [El RE:Documents as discussed Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui lding 3 I, Room 7 A-03 31 Center Drive , MSC 2520 National Institu tes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infectious Disease s (NlAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Dieffenbach , Carl (NlH/NIAID) [E] Date: Friday, April 24, 2020 6: 13 PM To: Fauci, Anthony (NTH/ NlAID) [E] Subject: FW: Documents as discussed ----------------=-:,-:-= -------- (b)( (b)(6) > Dr. Fauci , l feel compelled to let you know directly when ever l talk to or correspond w ith an [C Director. I know you asked him to reach out. Just closing the loop. Carl ----- Original Message- ---From: Dieffenbach, Carl (NTH/NTATD) [E] Date: F1;day, April 24, 2020 6: 11 _PM ______ ~= To: Singer, Dinah (NIH/NC[) [E] ______ Cb _> _ <_ ; Sharp less, Norman (NII-I/NC I) [E] (b)( > Cc: Fauci , Anthon (NTH/NTAlD) [E] (b)(6) Auchincloss , Hugh (NTH/NIATD) [E] (b) (6)> ; Erbelding , Emily (NIH/NIAID) [E] (b) (6) ; Cassett i, Cr istina (NIH/NIAID) [EJ...._____,, __ ,___ Cb _) _(6).> Subject: Documen ts as discussed Dinah and Ned, Jt was a pleasure talking to you about what you are considering . As we discussed, here is the NIAID Strategic Plan that was just published , and two models of funding opportunity announcements for you to consider as models. I also think the Cancer Centers have aspects of collaboration , shared facilities, and research focus that you can borrow. So much of what NlAlD has built is modeled on the Cancer Centers. NWD strategic plan for COYID-19 https: //www .nia id.nih .gov /site s/ default / tiles/ NIA ID-COY 10-19-Strategic-P lan-2020. pdf Current Cente rs for ATDS Research FOA htips://grant~.nih.gov/grants lguide/pa -fi les/par-20-1 06.html Thi s is a very old RF A. Tam sending it because it wa s NTAID's first attempt to build rese arch capacity for the Level 3 and Level 4 pathogens after the Anthrax events. The current versions of the RF As have been limited competitions and are a Jess relavant. https: //grants.nih .gov/ grants /guide/rfa-fi lesirfa-ai-04-032.html With best rega rds, Carl Carl W. Die ffenbach, Ph.D. Director Division of AIDS, NIAID 560 l Fishers Lane , Room 8D34 {he, him, his) Rockville , MD 20852-983 l Phone: (b) (6) Ce ll: (b)(6) Fax: (240) 627-3466 The informa tion in th is e-mail and any of its attachm ents is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have rece ived this e-mail in en-or please inform the sen der and delete ii from your maibox or any other storage devices. The NfAID shall not acc ept liability for any statem ent made that are the sender 's own and not expressly mad e on behal f of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 21 :05:18 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Interview - john lauermann From: Date: To: Subject: Yes. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496~ 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------, .....,....,= From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, April 24, 2020 7:12 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Interview - john lauermann Impo rt ance: High (b) (6)•> (b)(6) ~=======~ (b)(6l>= Ok to schedu le? This is cleared From: Joh n Lauerman 1 8 : 46: 1 6 To: Cc: (BLOOMBERG/ NEWSROOM : ) At : 04/1 4 /20 (b)(6) (b)(6) (b) (6) ' (b)(6) Subject : RE : Inte r view Hi J ennife r et a l : He r e ar e a few q ues ti ons fo r Dr . Fa uci . Scientists from the Un i versity of Bri s tol found that the coronavirus has u ne x p ec t ed t endenc y t o large mut a t i ons in t he spi ke protein when its grown in monkey cells . This ha d been seen b efore as a virus t h at was u n wi ll i ng t o mutat e . Does a n y co n cer n s about vaccine design a n d effec t ive n ess? I t n ow appears a n t ibodies to for this? Has any implications i nves t i gati n g sequesters in t h is crea t e t h at some peop l e wh o recover from Cov i d h ave n o t h e SARS-Cov2. Wh at are t h e poss i b l e ex p l a n at i o n s it occurre d in other vira l d iseases? Does it have fo r the e ffectiveness of vaccines? Is NIAI D t hi s? I s th ere a poss i b il ity t h at t he v i rus cells ? An o t h er fea tu r e of coro n av i ruses appears t o be ra p i d l y wa nin g immunity . Has this been seen in any NIAID experiments? What does t his s u ggest abo u t the vir u s ' s ability to evade the immu ne syst em? A l ab or at ory at Oxford h as suggested that , if al l go es we ll , t h e y may be f ini s h ed with p h ase 3 t r i a l s in 5000 p eo p l e by t h e fall , which co u ld mean as early as Septe mber . Does that so u nd realistic to you? Some compa ni es are aski n g regu l ators t o ma ke sure t h at safe ty standards are u pheld for ma ker s of Covid vaccin e s , and that c o r ne rs aren ' t cu t . Is i t wor t h cut t ing some safe t y co r ne rs t o ge t a Cov i d vacc ine read y for distr i bution? How ma n y p eo p l e s h ou l d t he Mod erna va cc i n e be t es t ed 3? How l o n g wou l d you e x p ec t t h o s e t r i als t o tak e? Th a n ks very muc h, 2035 25 1 028 h o p e we ca n se t t hi s up soo n . All At : 0 4 / 12 / 2 0 ------------La u er man (BLOOMBERG/ NEWSROOM : ) E'rom : To: John Cc: (b)( 6) .----- Cb _H__ 6J I in i n p h as e best , JL +44 22 : 38 : 36 (b)( ~ ' (b)( 6) Subject : RE : Inte r view Hi John - sorry we are still trying to get somethi ng arranged. Could you send your questions . Thanks, Jen Jennifer Routh [E] News and Science Wri ting Bran ch Office of Comm unications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclai m er: The informat ion in this e-m ail and any of its attach ments is confiden tial and may conta in sens itive informat ion . It should not be used by anyo ne w ho is not the original intended recipient. If yo u have received th is e-mail in error please inform the sender and delete it from you r mailbox or any other storage dev ices. The Nationa l Instit ute of Alle rgy and Infect ious Diseases shall not accep t liabi lity for any state ments made tha t are se nde r's own and not express ly made on behalf of til e N IAID by o ne of its represen tatives. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sun, 26 Apr 2020 21 :00:27 +0000 Conrad, Patricia (NIH/NIAID) [E);Folker s, Greg (NI H/NIAID) [El RE: BOLIVIAN COVID-19 GUIDELINES I cannot co-aut hor anythi ng with th em. Make sure t hey do not slip my name in. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb) (6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ----------------=-o:-= -------- From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Saturday, Apr il 25, 2020 7:20 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6) > (b)(6); Folkers, Greg (NIH/NIA ID) [E) Subject: Fwd: BOLIVIAN COVID-19 GUIDELINES Sent from my iPhone Begin forwarded message: -----------------------~ = From: Qu ispe Cornejo Armin Alvaro Dat e: April 25, 2020 at 5:30 :30 AM EDT To: "Conrad, Patricia (N IH/NIAID) [E]" {NIH/N IAID) [C]" (b)(6)> Subject: BOLIVIANCOVID-19GUIDELINES Dear Ms. Patricia Conrad (b)( (b)( >, "Barasch, Kimberly > Dear Ms. Kimber ly Marie Barasch I hope you are well desp ite the current devastat ing world pandem ic. The Bolivian Society of Intensive Care together with the Bolivian Healthcare Ministry are writing the national guidelines for the manageme nt of COVID-19 in the critically ill patient, an issue that is an emergency worldwide and may become disastrous in the low-middle income countr ies of Latin America if not managed since the beginning with prec ise , accurate and uniform approaches . With our team in Erasme University Hospital in Brussels , Belgium, toget her with Professors Jean - Louis Vincent, Fabio Taccone, Jean Charles Preiser, Jacques Creteur, etc., we are preparing the mate rial with other Bolivian and Mexican intensiv ists , internists , infe ctologists, imagenologists. I wonder if Dr. Anthony Fauci would honor us coauthoring and reviewing our last version of some chapters of our guidelines. Best regards , SPE - CORNEJO, ~dicine PhD fellow (Fell.) ritica f UNA MJ - J beto/og[a - Educaci6n - SIZ member 1 I- Erasme 8177 ■ Cliniquesunlve,silair~d Ro 11£d lf n 11k 808 . 8 S \WM.erasme.ulb.ac.b Erasme I- Lien vers Disclaimer ■ Cllniquesuniversitair~sde Bruxelles ~outedr '"" lk 808 8 10708 ux lie'> sv.ww.erasme.ulb.ac,be From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sun, 26 Apr 2020 20:12:5 1 +0000 Alb ert i Saverio RE:spreading determinants of SARS-CoV-2 Thank yo u ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ------------ (b)( From: Alberti Saverio Date: Sunday, April 26, 2020 9:10 AM ---------~~ To: Auchincloss, Hugh (NIH/NIAID) [E] Subje ct : spreading determinants of SARS-CoV-2 ----------- (b)(6) Dear Tony, we are all witnessing the great effort your collabo rators and yourself are investing over this pandemic emergency . As you well know, in Europe and Italy we had the unfortunate priv ilege of having been first hit hard by t he pandemic, after China. We had t he opportuni ty of meta -analyzing data from 170 .000 patients in European countries , for associated determinants of the spread ing fo rce of COVID-19 . If this may provide a useful, albei t non gratifying, contr ibution for the US and other countries, we wou ld feel we had done our job . best wishes Saverio Prof. Saverio Alberti Genetica Medica Dipartimento di Scie nze Biomediche Universita di Messina Po liclinico "G. Martino" via Conso lare Valer ia 98 125 Messina (b)(6) Skype: email : ----- (b)(6) i ______,.. (b)(6) From: Date: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:58 :06 +0000 (b)(6) To: Subject: RE:Covid 19 Double Mechanism . By Dr Brogna Carlo Thank you for sending this. Best regar ds, AS Fauci Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------------=-:-=, -------- (b)(6) From: c.brogna@libero .it Date: Friday, April 17, 2020 7:51 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Covid 19 Double Mechanism . By Dr Brogna Carlo Dear Dr A. Fau cy, we don' t know each other. I was born (b)(6) I am a simple doctor in Medicin and live in a remote Italian region. I am no one . I trust in God that you can read my paper, being published. I send it to you to anticipat e the exit times becaus e I trust that we can really unders tand what Covid 19 is. Being nobody , I did what nobod y would have done. I used the few tools I had available and questioned all the papers and data published so far. I describe what the dual mechanism of the Covid-19 can be. I anticipate that the resu lt conclusioni is not to my credit but I have been helped. I wish you a good read. May God bless us. Sincerely w ith love, Dr. Carlo Brogna M.D. (b)(6) Italia Avellino -lsernia From: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:56:13 +0000 To: Goletti Delia Cc: Fabrizio Cantin i; (b)(6) Lerner, Andrea {NIH/NIAID) [E];Cassetti, Cristina {NIH/NIAID) [E];Marston, Hilary {NIH/N IAID) [E];Greg Folkers (b)(6) Subject: RE: impact of bari citini b in COVID-19-an off label study CONFIDENTIAL Date: Thank yo u, Delia. I appreciate t he info rmat io n. Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidentia l and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representati ves. From: Golett i Delia (b)(6h Se nt : Friday, Apri l 17, 2020 8:03 AM To: Fauci, Anthony {NIH/NIAID) [E] -------~= Cc: Fabrizio Cantini (b)(6) (b)(6} Subj ect : impact of baricitinib in COVID-19-an off label study CONFIDENTIAL dear dr Fauci, good morn ing. I hope you are fine. Apologies to dist urb you but it may be of your interest . I saw in the web t hat you {NIAID/Fauci)( https ://investor. Iii ly .com/news-releases/news-release-details/Ii lly-begi ns-cli n ica1-testing-the rapies-covid-19 ) will be support a tria l using Baricit inib as part of the ACTTtria l ... I collaborated with Fabrizio Cantini {he reads in cc), a reumathologist of Prato to write a letter to J Infection {pdf attached). He conducted an off- label study in patients with mild -moderate pneumonia with COVID-19 [(SpO2) >92% at room -air, and rat io arterial oxygen part ial pressure/fractional inspired oxygen {PaO2/FiO2) 100-300 mm Hg] to evaluate the impact ofbaritinib {tablet 4 mg/day) in terms of safety, clinical respiratory improvements, discharge, ICU tr ansfer in 2 we eks; these pati ents received also lopinavir/ritonavi r therapy. The last consecutive patients with moderate COVID-19 pneumonia receiving standa rd of care therapy (lopinavir/ri tonavir and hydroxychloroquine) admitted before the date of the fi rst baricitinib -treated patient served as controls. The results of this off-label study, with the limit of not been a RCT,are encouraging: 1. Safety: only 1/12 case of transaminase elevation at day 10, likely due to lopinavir ritonavir coadministration because baricitinib is mainly renal secreted 2. Respiratory improvement : Sp02 and ratio arterial oxygen partial pressure/fractional inspired oxygen (Pa02/Fi02) significant ly improved; 3. Discharge in 7/12 vs 1/12 4. ICU transfer (0/12 vs 4/12) I do hope it may be a useful, although I am aware that it is a very preliminary info for you. Thank you for your attent ion. All the best Delia -------- Oa: Fauci, Anthony (NIH/NIAID) [E] 1nviato: giovedl 16 aprile 2020 00:02 A: Goletti Delia (b)(6) Oggetto : RE: Italian press...for you! (b)(6) Delia: Thank you very much for sending these. Best regards, Tony From: Goletti Delia (b)(6)> Date: Wednesday, Apri l 15, 2020 2:51 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,a Subject: Italian press...for you! (b..,.. )= (6) Dear dr Fauci, I disturb you only to let you know that the Italian press is with you! Dr Ippolito asked me to cont ribute to prepare a document in support of you which I did with all my hearth . I gave my very minor contribution in supporting the scientific journalist, but with a lot of proud for you . If you do not have it, below are the some of the links in your favor . https://apnews.com/27feaca21519a5eaf555c01313d33b91 https://apnews.com/b59d0a2c4c53f1c63a074b0d375fec23 https://www.nytimes.com/aponl ine/2020/04/15/world/europe/ap-eu-virus-outbreak-italy-fauci.html https://www .nytimes.com/aponline/2020/04/15/business/ap-virus-outbreak-the-latest.html https://www.washingtonpost.com/world/europe/italian-virus-hospital-offers-fauci-work-if-trump-fireshim/2020/04/15/9b9afac0-7f16-11ea-84c2-0792d8591911 story.html https:// a bcnews .go. com/Health/wireStory/italian-virus-hospital-off ers-fa uci-work-trump-fires-70160122 https://www.ilfattoquotidiano.iU2020/04115/coronavirus-direttore-spallanzani-scrive-a-mattarella-econte-il-licenziamento-di-fauci-sarebbe-un-disastro-e-non-solo-per-usa/5770793/ https://www.repubblica.it/salute/med icina-ericerca/2020/04/15/news/per favore non silurate anthony fauci-254087254/ https://www.sanitainformazione.it/politica/emergenza-covid-19-negli-usa-anthony-fauci-rischia-illicenz iamento-lappello-di-ippolito-spallanzani/ https://www.adnkronos.com/fatti/cronaca/2020/04/15/coronavirus-pazienti-dimessi-dallospallanzan i pu DuaZKkoJ NyLCZ 11DlgPN .html all the best Delia Da: Goletti Delia ______ lnviato: domenica 12 aprile 2020 19:57 A: Fauci,Anthony (NIH/NIAID) [E] Oggetto: R: all my gratitude and an update ____, (b) (6)> Thank you for your time! Best regards Da: Fauci,Anthony (NIH/NIAID) [E) -------- (b)( > lnviato: domenica 12 aprile 2020 19:53 A: Galetti Delia (b)(6) Oggetto: RE:all my gratitude and an update Delia: Many thanks for your kind note. It is much appreciated. I am pleased to see that you are getting involved in COVID-19 work. Keep up your excellent work. Best regards, Tony From: Goletti Delia (b)(6) Date: Sunday,April 12, 2020 11:02 AM To: Fauci,Anthony (NIH/NIAID) [E] ----Subject: all my gratitude and an update --:a(b)""'(= 6).> dear dr Fauci , apologies to write you in these busy days. It is only to express all my gratitude for what you have done in your life to fight infectious diseases and what you are doing now for COVID-19. Your efforts and achievement are in front of the whole world and for me it is a great honor to have been with you in 1992-1996 at the time of HIV fight. As I told you many times , you are a model of excellence! Only to keep you updated in my life, I am fine , and I mainly work as an ID specialist and scientist at the same place in Rome, the Nationa l Institute for Infectious Diseases L. Spallanzani. I am doing 2 days a week outpatients TB clinic and I run a small laboratory on TB research. However , given the pandemia, I shifted the lab activities on COVID-19, in particular on: 1. the role of coinfection (COVID-19 coinfection with tuberculosis, or COVID - 19 coinfection with HIV) on the modulation of the in vitro immune specific-response to SARS-CoV-2, or M. tuberculosis or HIV in cells from COVID-19 patients at different clinical stage 2. in vitro evaluation of the immunological and virological effect of baricinib, an anti-JAK1 and -JAK2 drugs, used in reumathoid arthritis , that has shown using BenevolentAl 's proprietary artificial intelligence-derived knowledge graph , as an agent that reduces the SARS-CoV-2 endocytosis into target cells potentially inhibiting the entry. Moreover , I would be happy to contribute in any activity you may think I am useful. I wish you a happy Easter in this blessed day. Thank you for your attention and fo r having had the possibility of working with you that has been crucial in my personal and professional life. All the best Del ia Delia Goletti, MD, PhD Clinica l Inves tigator , Labo rat o rio d el Vecch io, Room 13 Head of Translat ional Research Uni t Department of Epidemiology and Preclinical Research National Institute for Infectio us DiseasesL. Spallanzani Via Portuense 292, Roma 00149 Italy Tel:___ (b) (6), Fax: +39-06-5582-825 E-mail addr ess ( http://www .inmi .it/ ri cerca t r aslaziona le .htm l; h ttp://www. Profes sor of Patho logy, Unicarnillus University Rome, Italy in m i.it/ ricerca tras lazionale e nglish.ht ml Visiting Professor, Centre for lmmunobiology, B!izard Institute, Que en M ary Un iv(?fSity of London, UK ® LN ICAMILLUS Top Ital ian Wom en Scientist From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Apr 2020 14:41:5 1 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Expert U.S. pan el develops NIH treatment guideline s for COVID-19 Please send me our press release related to the guidelines Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Tuesday, April 21, 2020 8:46 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Lane, Cliff (NIH/NIAID) [E] (b)( ; Folkers, Greg (NIH/NIAID) [E] (b)(6); Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 ------ ::;..,..-,= --------- Your thoughts o n Cliff et al do ing a COCAcall about the new guidel ines? (COCA= CDC'sClinician Outrea ch and Commun icati on Activity) From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 8:37 PM To: Lane, Cliff (NIH/NIAID) [E]______ (b)(6) Cc: Pau, Alice (NIH/NIAID) [E)______ (b)(6) ------~~ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [E] Cb _H_6)>; Doepel, Laurie (NIH/NIAID) [E) Subject: RE: Expert U.S. panel develops NIH treatment guidelines for COVID-19 (b)(5) -----------------------to night .... (b)(5 We don' t have t o decide this From: Lane, Cliff (NIH/NIAID) [E] -------- (b)(6) Date: Tuesday, April 21, 2020 8:20 PM ------,;= Masur, Henry (NIH/CC/CCMD) [E] ---------- To: Billet, Courtney (NIH/NIAID) [E] (b) (6) > (b)(6)>; Cc: Pau, Alice {NIH/NIAID) [E_______ Cb) _~... 6) Doepel, Laurie (NIH/NIAID) [E) (b)(6)> Subject: Re: Expert U.S. panel develops NIH t reatment guidelines for COVID-19 (b) (5) From: "Bi lle t, Courtney (NIH/NIAID) [El" Date: Tuesday, April 21, 2020 at 3:49 PM (b)(6) L To: "Lane, Cliff (N IH/NIAID) [E]" CbH6)j, "Masur, Henry (NIH/CC/CCMD) [E]" (b)( > Cc: "Pau, Alice (NIH/NIAID) [El" (b)(6), Laurie Doepel (b)(6) Subject: FW: Expert U.S. panel develops NIH treatment gu idelines for COVID-19 Please advise? (b) (6)> From: Hall, Bill (HHS/ASPA) Date: Tuesday, April 21, 2020 3:46 PM To: Billet, Courtney (NIH/NIAID) [E] (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 -------- -----~~ Would Cliff and company want to participate in a COCAcall that CDCcould put on? From: Bonds, Michelle E. (CDC/0D/OADC) ------ (b)(6)> Date: Tuesday, April 21, 2020 2:44 PM To: Hall, Bill (HHS/ASPA) (b)(6) Subject: FW: Expert U.S. panel deve lops NIH treatment guidelines for COVID-19 I see the NIH treatment guidelines news release is out. Are you still interested in hosting a COCAcan on these guidelines? Subject: FW: Expert U.S. panel deve lops NIH treatment gu idelines for COVID-19 Just out, press release from NIH: Expert U.S . panel develops NIH treatment guidelines for COVID -19 04/21/2020 11:30 AM EDT "Living document" expected to be updated often as new clinical data accrue. ExpertU.S. panel developsNIH treatmentguidelinesfor COVID-19 "Living document" expected to be updated often as new clinical data accrue. Colorized scanning electron micrograph ofan apoptotic cel l (green) infected with SARS-COV-2 virus particles (orange), isolated from a patient sample. Image captured at the N LAID Integrated Research Facility {lRf) in F01t Detrick . Maryland.N/A/D A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COV ID-1 9). These guidelines, intended for healthcare providers , are based on published and preliminaiy data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for patients during the rapidly evolving pandemic. The guidelines are posted online (covid 19treatmentguidelines.nih.gov) and will be updated often as new data are published in peer-reviewed scientific literature and other authoritative information emerges. The guidelines consider two broad categories of therapies currently in use by healthcare providers for COVID-19: antivirals , which may target the coronavirus directly, and host modifiers and immune-based therapies , which may influence the immune response to the virus or target the virus. The panel 's conclusions about treating COVJD-19 with various agents that fall into these two classes of therapies are distilled in summary recommendations. Subsequently , the document provides background information about each agent-such clinical trials, and known interactions with other drugs-that as clinical data about its use, ongoing forms the basis for the Recommendation. Tables briefly outline the same information. The guidelines also describe the evaluation and stratification of patients based on their risk of infection and severity of illness. Recommendations in this section address best practices for managing patients at different stages of infection, for example: • Outpatients who are either asymptomatic or who have mild to moderate symptoms and are selfisolating • Inpatients with severe illness or critical disease Special considerations for pregnant women and for children who are infected are also included. A comprehensive section of the guidelines addresses a range of considerations for clinicians caring for the most c1itically ill hospitalized patients. This section includes multiple recommendations for patients needing critical care, including infection control procedures, hemodynamic and ventilatory support, and drug therapy. Finally, the guidelines include recommendations concerning the use of concomitant medications. These include statins; corticosteroids;non-steroidalanti-inflammatory drugs; and certain drugs used to conlrnl hype rtension, known as ACE inhibitors and ARBs. The treatment guidelines panel is co-chaired by Roy M. Gulick, M.D., chief of the Infectious Disease Division at Weill Medical Hospital of Cornell University, New York City; H. Clifford Lane , M.D., clinical director of the National Institute of Allergy and lnfectious Diseases, National Institutes of Health; and Herny Masur, M.D., chief of the Critical Care Medicine Department at the NIH Clinical Center. Members of the guidelines panel, appointed by the co- chairs, were chosen based on their clinical experience and expertise in patient management, translationa l and clinical science , and/o r the development of treatment guidelines. They include 30 experts drawn from U.S. healthcare and academjc organizations,federal agencies, and professional societies. About the National Institutes of Health (NIH) : NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the p1imary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more informat ion about NIH and its programs, visi t www.nih.gov. From: National Institutes of Health (NIH) Date: Tuesday, April 21, 2020 12:32 PM = To: Bedrosian , Sara (CDC/0D/OADC) ----~ (b)(6) Subject: Expert U.S. panel develops NIH treatment guidelines for COVID-19 Hav ing 1rouble view ing this emai l'.' View it as a Wch oage. You are receiving 1his message because you are subscribe:!10 News Releases for Na1ional lnstitu1es of Heallh (NIH). Expert U.S. panel develops NIH treatment guidelines for COVID-19 04/21/202011:30AM EDT "Living document" expected to be updated often as new clinical data accrue. Update Your E-mail Address I Add Subscriptions I Unsubscribe If you have questions or problems with the subscription service, please contact subscriberhelp .govdelivery.com . For all other inquiries about NIH programs and activities, please contact Ask NIH . Before writing, please view our Freguently Asked Questions page , our Health Information page, or Search our website. This service is provided to you by the National Institutes of Health . NIH ...Turning Discovery Into Health ® This email was sent to eri7@cdc .gov using GovDelivery Communications Cloud on behalf of: Nationa l Institutes of Health (NIH) · 9000 Rockville Pike · Bethesda MD 20892 · 30 1-496-4000 I TTY 30 1-402-9612 D From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 24 Apr 2020 01:11:10 +0000 To: Marks, Peter;Collins, Francis (NIH/OD) [El Cc: Mascola, John (NIH/VRC) [E);Disbrow, Gary (OS/ASPR/BARDA);Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) Subject: RE:Vaccine Development Attachments: Warp Speed Brief Deck 0800 042220 .pptx Peter: Happy to discuss at your convenience - sooner rat her than later . Let us make sure that we ----------------------- (b)(5) CbHS l . Happy to discuss this in deta il with you. Best regards, Tony From: Mar ks, Peter Date: Thursday, April 23, 2020 5:50 PM To: Collins, Francis (NIH/OD) [El -----(b)(6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) CbH > (b =),,.., (6J = >; Fauci, Anthony (NIH/NIAID) [E] (b)(6J; Disbrow, Gary {OS/ASPR/BARDA) Subject: Vaccine Development Dear Francis and Tony, I know that you have heard murmuring about Proj ect Warp Speed. We had a call today w ith John Mascola, Carl Dieffenbach, Hilary Marston, Mary Marovich and Emily Erbelding to go through t he proposal and discuss how it could feed into the ACTIV effort. Cb)(SJ They suggested that I contact you to try to set up a brief call to go over the plan. I am attaching a slide deck that provides an overview and am happy to find the time whenever you are available. Thanks so much for consideri ng, Peter From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/NIAID) [El Wed, 22 Apr 2020 00:29:08 +0000 Collins, Francis (NIH/OD) [El,------;;, Cb "'"" H= Viral Clades Brufsky 42020 Accepted Final.pdf Viral Clades Brufsky 42020 Accepted Final.pdf Here is the paper fro m Pittsbu rg on the mutations. commentary from China on another study I will send on separate e-ma il the From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 21, 2020 3:43 PM = To: Graham, Barney (NIH/VRC) [El-------~ CbH6)> Cc: Mascola, John {NIH/VRC) [El (b)(6) Subject: FW: Viral Clades Brufsky 42020 Accepted Final.pdf This is rea lly gett ing inte rest ing. See att achm ent. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6)> Date: Tuesday, April 21, 2020 3:28 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Redfield, Robert R. {CDC/OD) (b)(6)>; Debi Birx (b)(6)> Subject: Viral Clades Brufsky 42020 Accepted Final.pdf ------~~ ----- Sorry for all of th e emails. I spoke to Adam who is an oncologist . I t hought th is might be of int erest. Steve Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:29:10 +0000 Birx, Deborah L. EOP/NSC RE:Sero logy Test Calculator From: Date: To: Subject: (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Birx, Deborah L. EOP/NSC (b)(6)•> Date: Tuesday, April 21, 2020 4:06 PM (b)( To: Hahn, Stephen (b)(6)>; Fauci, Ant hony (NIH/NIAID) [E] _:...:...:..!:====~;:--Redfield, Robe rt R. (CDC/OD) (b)(6)>; Giroir, Brett (OS) (b)(6)l> Subject: Re: Serology Test Calculator (b)(5) Deb CbH > Date: Tu esday, April 21, 2020 at 3:23 PM To: "Birx, Deborah L. EOP/NSC" CbH6)>,"Red fi eld, Robert R (CDC)" ____ From: "Hahn, St ephen" ---------~~ ======== (b ')( ;::' ~6) CbH6) , "Fauci, Anthony S (NIH)" Cb _H_6)>, "Giroir , Brett (OS)" Subject: Fwd : Serology Test Calcula t or From: Shuren, Jeff (b)(6) Date: April 20, 2020 at 6:26:14 PM EDT To: Hahn, Stephen (b)(6)>, Lenihan, Keagan ----------- (b)(6)>, Shah, Anand (b_H_6)>, Rom, Colin...________ Subje ct : Serology Test Calculator _________ (b_~_<~ Attached is a very rudimentary calculator that you are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negative predictive value of individual serology tests and the use of two tests by plugging in the known or estimated sensitivi ty, specificity, and population prevalence of COVID-19. (b)(5) From: Date: To: Subject: Att achments: Fauci, Anthony (NIH/N IA ID) [E) Tue, 21 Apr 2020 20:28:43 +0000 (b)(6) FW: Serology Test Calculator Calculat or for PPV and NPV for indiv idual tes ts and comb ined protect ed.x lsx I w ill call you about thi s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6):> Se nt : Tuesday, April 21, 2020 3:23 PM To: Debi Birx (b)(6); Fauci, Anth ony (NIH/NIAID) [E] ---:---:-:-::-:~-:::-:-;;::::::===-~ ___ ;....;....;..:::=~~,----Redfie Id, Robert R. (CDC/OD) (b)( 6)•> ; Giroir, Brett (OS) CbH > Subj ect: Fwd : Serology Test Calculator (b)(6) -------- ---------- (b) (6)> From: Shuren, Jeff Date: Apr il 20, 2020 at 6:26 :14 PM EDT To: Hahn , Stephen (b)(6), Lenihan , Keagan ___ .....:__:....____,!=~~~--__ ___:,_ _:::, _~~~~------(b)( 6), Rom, Colin (b)(6)> ---------Subject: Sero logy Test Calculato r (b)(6J>, Shah, Anand --------- Attached is a very rudimentary calculator that yo u are welcome to share with the WHTF/HHS serology WG to calculate the positive predict ive value and negat ive pred ictive va lue of individual serology tests and the use of two tests by plugg ing in the known or estimated sensitivi ty, specificity, and population preva lence of COVID-19 (b) (5) Calculator for Positive Predictive Value (PPV) and NeQative Predictive Value (NPV) for individual tests and combined Prevalence 5.0% Test 1 Test 1 %Pos1 %Neg1 PPV1 for NPV1 for Sen1 Sp1 (Test1 =pos) (Test1=pos) (Test1 =neg) (Test1 =neg) 97.0% 93.2% 11.3% 42.9% 88 .7% 99.8% Test 2 Test2 %Pos2 %Neg2 PPV2 for NPV2 for (Test2=pos) (Test2=pos) Sen2 Sp2 (Test2=neA) l(Test2=neA) 8.2% 53.7% 91.8% 88.0% 96.0% 99.3% Combined %Pos (Test1 =pos, Test2=pos) 4.5% PPVfor (Test1=pos, Test2=pos) 94.3% %Discordant (Test1 =pos, Test2=neg) 6.8% NPVfor (Test1 =pos, Test2=neg) 91.4% %Neg (Test1 =neg) 88 .7% NPV for (Test1 =neg) 99.8% From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 18 Apr 2020 22:21:37 +0000 To: Hahn, Stephen Cc: Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Caliguiri , Laura (FDA/OC);Lenihan, Keagan (FDA/OC);Shuren, Jeff (FDA/CDRH);Lane, Cliff (NIH/NIAID) [E];Shah, Anand (FDA/OC) Subje ct: RE:medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California Great idea! Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hahn, Stephen (b)(6):> Date: Saturday, Apr il 18, 2020 6:19 PM ------~~ To: Fauci, Anthony (NIH/NIAID ,..: )~[_; E):.::======-~ Cc: Birx, Deborah L. EOP/NSC (b)( >; Redfi eld, Robert R. (CDC/OD) (b)(6); Kadlec, Robert (OS/ASPR/1O) (b)( ; Caliguiri, Laura (FDA/OC) (b)(6); Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff ":"'""-:--------:-:=======:!.:...-~____; (FDA/CDRH) CbH6>:; Lane, Cliff (NIH/NIAID) [E] (b)(6) ; Shah, Anand (FDA/OC)_;..:======::;: (b:;::, )(c=: 6);-' Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, Californ ia Team, Anand Shah, Deputy Commissioner, reached out to t he Stanford investigator s on our behalf. Very interesti ng informa ti on regarding their research and the test that they are using. They are interested in partnering with us. I'll let Anand give the detai ls. Anand will be reaching out to the MGH fo lks, as we ll. Steve (b)(5) (b)( 6) From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 3:38 :39 PM EDT To: Hahn, Stephen (b)(6) (b)(6) Cc: Birx, Deborah L. EOP/NSC (b)(6)>, Redfield, Robert R (CDC) Kadlec, Robert P (OS) (b)(6), Caliguiri, Laura (b)(6), Lenihan , Keagan (b)(6)>, Shuren, Jeff (b)(6)>, Lane, Henry c (NIH) .__ _____ _ ~_(6) Cb _ > Subject: RE: medRxiv: COVID-19 Antibody Sero prevalence in Santa Clara County, Califo rni a .....:.----=====~~~--:~ -=======~~-- --------- Steve: John Ioann idis is the one that most of us know. people could reach out to . Thanks, Tony He is the person one of your Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892 -2520 Phone : (b)(6) FAX : (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received t his e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)(6) Date: Saturd ay, Apr il 18, 2020 3:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Birx, Deborah L. EOP (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6J>; Kadlec, Robert (OS/A5PR/IO} (b)(6)>; Caliguiri, Laura (FDA/OC} (b)(6)> ; Lenihan, Keagan (FDA/OC} (b)(6); Shuren , Jeff (FDA/CDRH) (b)(6); Lane, Cliff (NIH/NIAID) [El (b)(6) Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California ------~~ __ ;_;;_.;..::;:======~ ~ "'.'"""'--:-------.=====:::_:---,_,.....,_; We can certainly work with them . Does anyone know any of these folks? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: April 18, 2020 at 10:51:33 AM EDT Cb _H_6) (b)(6) To: Hahn, Stephen Cc: Birx, Deborah --::-::-:--::-:-::-:-:.:===:------~= L. EO _:.P/_N_S_C.!::=====-=~:--~Cb _H_6) Kadlec, Robert P (OS) Lenihan, Keagan C (NIH) ______ Redfield, Robert R (CDC) (b)( >, (b)(6), Caliguiri , Laura (b)(6)>, (b)(6) Shuren, Jeff (b)(6)>, Lane, Henry Cb _H_6J Subject: RE: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California St eve: Thanks for th e quick reply. The dat a from th e Stanford group ------- (b) (5) Thanks, Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Hahn, Stephen (b)( > Date: Saturday, Apr il 18, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E]____ ~_ Cb _) ~ (6) ~>~ Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfie ld, Robert R. (CDC/OD) (b)(6)>; Kadlec, Robert (OS/ASPR/1O) (b)(6)>; Caliguiri , Laura (FDA/OC) (b)( v>; Lenihan, Keagan (FDA/OC) (b)(6); Shuren, Jeff L;-: ( F :::D-:A-:-: /C:::D:--:R-:-: H-:-:; ) ====:::!:::...:..:.:...;.,, (b;;. )(;..;, 6) ------~= ---------- Subject: Re: medRxiv: COVID-19 Ant ibody Sero prevalence in Santa Clara County, California Tony, (b) (5) (b) (5) (b)(5l. Steve From: Fauci, Anthony (NIH/NIAID) [E] Date: April 18, 2020 at 10:03:32 AM EDT To: Hahn, Stephen (b) (6) Cc: Birx, Deborah L. EOP/NSC Kad Iec, Robert P (OS) (b)(6)> (b)(6) (b)(6)>, Redfield, Robert R (CDC) ------- (b)(6) Subject: FW: medRxiv : COVID-19 Antibody Seroprevalence in Santa Clara County, California Steve: (b) (5) Thanks, Tony From: Folkers, Greg (NIH/NIAID) (E] (b)(6) Date: Friday, April 17, 2020 5:44 PM Subject: medRxiv: COVID-19 Antibody Seroprevalence in Santa Clara County, California COVID-19 Antibody Seroprevalence in Santa Clara County, California Eran Bendavid, Bianca Mulaney, Neeraj Sood, Soleil Shah, Emilia Ling, Rebecca BromleyDulfano, Cara Lai, Zoe Weissberg, Rodrigo Saavedra, James Tedrow, Dona Tversky, Andrew Bogan, Thomas Kupiec, Daniel Eichner, Ribhav Gupta, John Ioannidis, Jay Bhattacharya doi: https://doi .org/10.1101/ 2020.04.1 4 .20062463 • Abstract • Info / History • Me t rics • Preview PDF Abstr act Background Addressing COVID-19 is a pressing health and social concern . To date, many epidemic projections and policies addressing COVID-19 have been designed without seroprevalence data to inform epidemic parameters. We measured the seroprevalence of antibodies to SARS-CoV-2 in Santa Clara County. Methods On 4/3 -4/4, 2020, we tested county residents for antibodies to SARS-CoV-2using a lateral flow immunoassay. Participants were recruited using Facebook ads targeting a representative sample of the county by demographic and geographic characteristics. We report the prevalence of antibodies to SARS-CoV-2in a sample of 3,330 peop le, adjusting for zip code, sex, and race/ethnicity . We also adjust for test performance characteristics using 3 different estimates : (i) the test manufacturer's data, (ii) a sample of 37 positive and 30 negative controls tested at Stanford, and (iii) a combination of both. Results The unadjusted prevalence of antibodies to SARS-CoV-2 in Santa Clara County was 1.5% (exact binomial 95CI 1.11-1.97%), and the population -we ighted prevalence was 2.81% (95CI 2.24-3.37%). Under the three scenarios for test performance characteristics, the populat ion prevalence of COVID-19 in Santa Clara ranged from 2.49% (95CI 1.80-3.17%) to 4.16% (2.58-5.70%). These prevalence estimates represent a range between 48,000 and 81,000 people infected in Santa Clara County by early April, 50-85-fold more than the number of confirme d cases. Conclusions The population prevalence of SARS-CoV-2 antibod ies in Santa Clara County implies that the infection is much more widespread than indicated by the number of confirmed cases. Population prevalence estimates can now be used to calibrate epidemic and mortality projections. From: Date: Fauci, Anthony (NIH/N IAID) [E) Tue, 21 Apr 2020 03:05:43 +0000 clane@niaid.nih.gov FW: FYI- " Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" To: Subject: Go for it. Congratulations!!! Q From: Hall, Bill (HHS/ASPA) (bH > Date: Monday, April 20, 2020 10:07 PM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b)""' (6) = > Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6J>; Myles, Renate (NIH/OD) [E] (b)(6); Burklow , John (NIH/OD) [E) (b)(6) Subject: Re: FYI- "Coronavirus Disease 2019 {COVID-19)Treatmen t Guidelines" -------Hi Tony, ---------------- (bX5)PCP.. I've told John B/Renate/Courtney that everything can post first thing tomorrow morning. Best regards, Bill From: Fauci, Anthony (NIH/NIAID) [E]______ _ )_C6J (b _ > Date: Monday, April 20, 2020 11:53 Afvl To: Miller, Katie R. (ovp.eop.gov) (b)(6); Short, Marc T. EOP/OVP (b) ( > Cc: Birx, Deborah L. EOP/NSC (b)(6)>; Redfield, Robert R. (CDC/OD) (b)( 6)j>; Billet, Court,_ n-ey- (':"'." N'.".". IH ""." /':"."' N'."."' IA '."". l~D:-: )[ :--: E':"': ] ===~-(b ""' );,(6) = ; Hall, Bill (HHS/ASPA) (b)(6) J>; O'Malley, Devin M. EOP/OVP (b)(6); (b)(6) ===== (b=)(=6)~1J>;.; = Lane, Cliff {NIH/NIAID) [E] (b)( ; Myles, Renate (NIH/OD) [E] --------r::-:-:= ---------- ----------=-:-~ ---- ====~ ~ ~===~~ == (b)( 6)j Subject: FYI - "Coronavirus Disease 2019 (COVID-19)Treatment Guide lines" Katie/Marc: Just as an FYI - "The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines" that were developed here at NIH, and a copy of which I provided to Deb Birx and ult imate ly to Mark Meadows is moving forward . Mark Meadows (b)(5) (b) (5) ----------------------------- (bH 5> Press release w i I1come from NIH w ith clearance through the appropriate channels (see attachmen t as an FYI). I anticipate that this will happen in th e next day or two . Thanks. Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- Fauci, Anthony (NIH/N IA ID) [E) Mo n, 20 Apr 2020 23:05:49 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ask to highlight the incredib le work of key federa l workers From: Date: To: Subject: Corr ect again. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: FAX: (30 (b)( 6) 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 20, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El CbH >; Billet, Court ney (NIH/NIAID) [El _,, (b)(6)>; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer (NIH/NIAID) [El (b)(6) _______ ------ == Subject: RE: ask to highlight the incredible work of key federal worke rs (b) (5) From: Fauci, Anthony (NIH/NIAID) [E] CbH > Date: Monday , April 20, 2020 4:52 PM To: Folkers, Greg (NIH/NIAID) [El ------- --== (b)(6) Billet , Court ney (NIH/NIAID) [E] (b)(6) ; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6) -------- Subject: RE: ask to highlight th e incred ible work of key federal worke rs I agree. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6)3 FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg {NIH/NIAID) [E] Date: Monday, April 20, 2020 4:52 PM To: Billet, Courtney (NIH/NIAID) [E]; NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] ; Routh, Jennifer (NIH/NIAID) [E] Subject: RE:ask to highlight the incredible work of key federal worke rs (b)(5) From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Monday, April 20, 2020 4:40 PM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E] (bH >; Routh, Jennifer (NIH/NIAID) [E] (b)(6)> Subject: FW: askto highlight the incredible work of key federal workers (b)(5) Any suggestions? From: Boyse, Natalie (OS/ASPA) (b)(6)> Date: Monday, April 20, 2020 4:28 PM To: Billet, Courtney (NIH/NIAID) [E] (bH >; Myles, Renate (NIH/OD) [E] ______ (b) _C6) _ >; Burklow, John (NIH/OD) [E] (b)( > Cc: Bird, Catherine (OS/OGC) (b)(6);Brennan, Patrick (OS/ASPA) (b)(6)> ------ ::;..,..-,= Subject: FW: ask to highlight the incredible work of key federal workers Hi John, Renate and Courtney - (b)(5) Let me know if you have any questions re: this request. I am avai lab le and happy to chat this afternoon. Thanks, Natalie Natalie Boyse Special Assistant, Immediate Office of the Secretary U.S. Department of Health & Human Services M,____ _ From: Baldw in, Brittany L. EDP/WHO (b)(6)> Date: Monday , April 20, 2020 3:00 PM To: Boyse, Nata lie (OS/ASPA) (b)(6) Subject: ask to highlight the incredible work of key federal workers --------~~ Hi Natalie - reat talking ·ust now . (b)(S)~ (b) (5) (b) (5) Please do not hesitate to reach out with questions! Brittany L. Baldwin Special Assistant to the President Speechwriter 0: (b)(6) ----- C: (b)(6) From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 12:01:43 +0000 Collins, Francis (NIH/OD) [E);Mascola, John (NIH/VRC) [E) Conrad, Patricia (NIH/NIAID) [E);McManus, Ayanna (NIH/OD) [E];Wood, Gretch en (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Barasch, Kimb erly (N IH/NIAI D) [C] Subject: RE: Pursuant to My Email on Friday I agree. Let us do it another time. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- > ------~:-:-= -------- From: Collins, Francis (NIH/OD) [ E] Date: Monday, April 20, 2020 4:59 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) (b)( CbH >; Mascola, John (NIH/VRC) [E] Cc: Conrad, Patricia (NIH/NIAID) IE] CbH ; McManus, Ayan na (NIH/OD) IE] Cb H 6)>; Wood, Gretchen (NIH/OD) IE] CbH6);Tabak, Lawrence (NIH/OD) IE] CbH >; Barasch, Kimber ly (NIH/NIAID) [C] (b)(6) Subject: RE: Pursuant to My Email on Friday With apologies , I jus t real ized that the ACTIV Vaccines working group (wh ich involves John in a sign ificant way, and will be joined today by Tai Zaks from Modern a) meets this morning from 9 -10 am. Probably we need to pick another ti me for this pow -wow about the CVP? Francis From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 19, 2020 9:41 PM ------=-cc-:-=(b)(6) To: Collins, Francis (NIH/OD) [E] CbH6J> 1 ; Mascola, John (NIH/VRC) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J; Tabak, Lawrence (NIH/OD) [E] CbH6J;Barasch, Kimber ly (NIH/NIAID) [C] (b) (6) > Subject: RE: Pursuant to My Email on Friday Patty: Please see if we can incorporate this call into our regular ly scheduled 9:00 AM call that actually includes some of the same cast of people. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) [E] < (b)(6)> CbH6J>;Mascola, John (NIH/VRC) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J>;McManus, Ayanna (NIH/OD) [E] CbH6J 1>; Wood, Gretchen (NIH/OD) [E] CbH6J>;Tabak, ~ Lawrence (NIH/OD) [E] (b)( v> Subject: RE: Pursuant to My Email on Friday ---~--"':"""""""':"".~==-.:......-_;_ __ Ill Can we have a phone call about this tomorrow at 9:15 am? Anyone else to include (Emily? Cliff?) Francis -------- From: Fauci, Anthony {NIH/NIAID) [El Date: Sunday, April 19, 2020 9:30 PM To: Mascola, John (NIH/VRC) [El ______ (b)(6) (b)(6)> --,;Cb H= '"" 6J>; Collins, Francis (NIH/OD) [El (b)(6) Cc: Conrad, Patric ia {NIH/NIAID) [E] ---------Subject: RE: Pursuant to My Email on Friday Francis: (b) (5) Best, Tony From: Mascola, John (NIH/VRC) [E] _______ Date: Sunday, Apri l 19, 2020 4:24 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) ------~= -------- Cb _>_C6) CbH >; Collins, Francis (NIH/OD) [E] --------- Cc: Conrad, Pat ric ia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday CbH > << File : Cov Vaccine Program HHS (draf t) 19April20.pptx » Tony, Francis, (b)(5) (b)(5) Happy to discuss. John (b)(6) --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) (b)(6) (b)(6),>; Collins, Francis (NIH/OD) [El =======--=:-;;--' CbH6J;Mascola, John INIH/VRC) [El CbH6J>;Bright , Rick (OS/ASPR/BARDA) CbH6J ; Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) (b)(6); Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; =======~~ --------- ---------=:-:-= Redfie Id, Robert R. (CDC/OD) CbH6J>;Messonnier, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) CbH6J>;Dareshori, Zack (HHS/10S) (b)(6) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (OS/10S) CbH6)>;Shuy, Bryan (OS/ASPR/10) (b)(6) CbH6J;Wolinetz, Carrie (NIH/OD) [E] Subject: Pursuant to My Email on Friday ----------------- ------------------ I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. This represents just a first step of many steps that first outlines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft.doc>> From: Cc: Fauci,Anthony (NIH/NIAID) [E) Mon, 20 Apr 2020 01:34:55 +0000 Mascola,John (NIH/VRC)[E) Conrad, Patricia (NIH/NIAID) [El Subje ct: RE: Pursuant to My Email on Friday Date: To: OK. Let us discuss tomorrow. (b)( > From: Mascola, John (NIH/VRC) [E] Date: Sunda y, April 19, 2020 6:11 PM To: Fauci, Anthony (NIH/NIAID) [E) < ".:::::======6-:--:= Cc: Conrad, Patricia {NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday --------- -------:a= Tony, One key point that may be easie r to review w ith 5 min call , whenever you get the chance. (b)(5) John From: Mascola, John (NI H/VRC) [E] Date: Sunday, April 19, 2020 5:13 PM To: Collins , Francis {NIH/OD) [E] Cc: Conrad, Patricia (NIH/N IAID)"":' [~ E]~=====---=- -------::-:--:-= (b)(6)> Subject: RE: Pursuant to My Email on Friday Francis, (b)(6) , (b"'"" )(= 6); Fauci, Anthony (NIH/NIAID) [E] (b) (5) If still not so clear , feel free to call. John (b)(6) -------- From: Collins, Francis (NIH/OD) [E] Date: Sunday, April 19, 2020 5 :04 PM -------~ (b)(6) = To: Mascola, John (NIH/VRC) [E] (b)( > ":'"":.:::=======..,.._ Cc: Conrad, Patricia (NIH/NIAID) [E] (bH6J>; Fauci, Anthony (NIH/NIAID) --------- (b)( 6) > [E] Subject: RE: Pursuant to My Email on Friday Hi John, Thanks for your thoughtful note. (b) (5) (b) (5) Francis From: Mascola, John (NIH/VRC) [E] < Date: Sunday, April (b)(6)> -------19, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------ -------- ~=>; (bH --------- Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Friday Collins, Francis (NIH/OD) [E] (b)(6)> << File: Cov Vaccine Program HHS (draft) 19April20.pptx » Tony, Francis, (b) (5) Happy to discuss. John (b)(6) From: Kadlec, Robert (OS/ASPR/IO) ---------Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/IO) ___ _;_ _ ___;_ _;_.:._.:.__.:._.:..:::::=====: (b)(6) CbH6)>;Collins, Francis (NIH/OD) [El Cb ~>:;; <6) ~>"""'"'.. ; Mascola, John (N IHNRC) [El 6b ; Bright , Rick (OS/ASPR/BARDA) CbH CbH6) ; Fauci, Anthony (NIH/NIAID) [El (b)(6)>; Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Patrick, Vanessa (OS/ASPR/BARDA) (CTR) (b)(6)1>; Moughalian, Jen (HHS/ASFR) CbH6)>; Redfield, Robert R. (CDC/ODJ CbH6>;>; Messonnie r, Nancy (CDC/DDID/NCIRD/OD) CbH6)>;Lane, Cliff (NIH/NIAID) IE] CbH6);Marks, Peter (FDA/CSER) CbH6);Yeskey, Kevin (OS/ASPR/IO) CbH6J> Cc: Harrison, Brian (HHS/IOS) CbH6)>;Dareshori, Zack (HHS/IOS) (b)(6J>; CbH6)>;Conrad, Patricia (NIH/NIAID) [E] Stecker, Judy (05/105) CbH6)>;Shuy, Bryan (OS/ASPR/IO) (b)(6) CbH6)>;Wolinetz, Carrie {NIH/OD) [E] =========~~ ---------- --------~~ ---------- -------Subject: Pursuant to My Email on Friday ---------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow . I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represente d in t hese products. This represents just a first step of many steps that first out lines a concept that will then be operationalized int o a histor ic effort for not only the Department and agencies w ho will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob << File: Vaccine strategy-200411-v 13.pptx >> << File: Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .doc» From: Date: Fauci, Anthony (NIH/N IA ID) [E) Wed, 22 Ap r 2020 14:55:57 +000 0 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C] FW: Coronavirus Quest ions for th e Offic e of th e Surgeon General To: Cc: Subjec t : Please make sure th at I call thi s person t omorrow ------------- (b)( Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) MEDCOM (USA) Se nt : Tu esday, April 21, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE: Coronavirus Questions for th e Office of the Surg eon Gener al ------~~ ---------- Dr. Fauci, Thank you for responding to my request for information. (b)(6) Please be safe. (b)(6) (b) (6) My cell phone number is (b)(6)-. ---------------------- r/ (b)(6) From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Tuesday, April 21, 2020 12:49 PM Cb_H_6) To: (b)(6) M_ E_ DC _O _M __:_ (U_S_A.:.! ) ==~~---Cb _H _6) Cc: Lerner , Andrea (NIH/NIAID) [E] (b)(6) Subjec t: [Non-DoD Source] FW : Coronavirus Questions for the Office of the Surgeon General --------- All active links contained in this email were disabled. Please verify the identity of the sender, and confirm the authenticity of all links contained within the message prior to copying and pasting the addres s to a Web browser. (b)(6) Thank you for your note . Shown below are my answers to your questions. hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition , maintaining connections with fami ly and friends (via phone calls, email, or video chatting) while physically socially distancing is very important . 2. Can COVID-19 be contracted from a corpse? Infect ion control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDC provides guidance on this issue here:Caut ionhttps:// www.cdc.gov /coronavirus /2019-ncov /hcp/guidancc-postmort emspecimens.html < Caution-https://www.cdc.gov/coronavirus/2019-ncov /hep/guidancepostmortem-speci mens.html> 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question , persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDC are effective. _ Caution-https: // www.cdc.gov /coronavirus/2019-ncov /hcp/ infection-controlrecommendation s.html?CDC _AA _refVal =https%3A %2F%2FCautionwww .cdc.gov %2Fcoronavirus%2 F20 l 9-ncov%2f infect ion-control %2Fcontro lrccommcndations.html < Caution-https :/ /www.cdc.gov/coronavi rus/2019-ncov /hcp/i nf ectioncontrol-recommen dations. html?CDC_AA_reNal= https%3A %2F%2FCautionwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Finfection-control%2Fcontrolrecommendat ions.html > In cases where inadequate PPEis worn , or if is not put on/ t aken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is th e most important th ing we should be do ing, other t han social distanc ing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one' s face with unwashed hands are cr itical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night, regard ing COVID-19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection. We are in that reality now, and what keep s me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best rega rds , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: 301 496-4409 (b)( 6) E The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender' s own and not expressly made on behalf of the NIAID by one of its representatives. _F_ ro_m_:.!::::======~ (b=)(~6) MEDCOM (USA)___________ (b) (6) Cb _>_< _ _ >> Se nt : Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavir us Questions for the Off ice of th e Surgeon General -------------------- ~~ > > (b)(6) Dr. Fauci, ----, (b)( ~= , the antiterror ism and insider threat office r for the Office of the Surgeon General I am (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty-four years, and this is new to me . I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens . I have a few questions for you: 1. How do you recom mend I reassure our staff on dea ling w ith the stressors of COVID-19? 2. Can C0VID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racting C0VID-19? 4. Are masks and gloves tru ly effective, if so, why are so many medical professionals contracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regarding C0VID-19? Thank you for your time and please be safe. r/ ------ Antiterror ism and Inside r Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) Cb)(6) (b)( (b)(6) ~NIPRNet: ~SIPR Net: Leve I I Antiterror ism Awareness Training: Caution-http://jko .jten .mil/courses/at! 1/launc h. html < Cautionhttp ://jko.jten .mil/courses/atl 1/launch. html > -------------------------------- Organizational Mailbox: Cb)(6) < mailto To submit contracts for AT/OPSEC review: Caut ion Caution(b) (6) > (b) (6).,..>___ Cb)~ _. Caution- "Not on My Watch" CONFIDENTIALITY NOTE: Thi s electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recip ient , and may not otherwise be distributed, copied or disclosed . The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediate ly by returning the electronic transmission and then immediately delete this transm ission, includ ing all attachments, without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this informat ion is Personal Data and must be protected from publ ic disclosure. From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 21 Apr 2020 17:48:36 +0000 To: (b)(6)1 Lerner, Andrea (NIH/NIAID) [El FW: Coronavirus Questions for the Office of the Surgeon General Cc: Subject: (b)(6) Thank you for your note. Shown below are my answers to your questions . hope that you find them helpful. 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? This is indeed an unprecedented and stressful time. Stress can often come from the unknown. In times of stress it is critical to take care of one's physical health, by eating well, getting enough sleep, and exercising. In addition, maintaining connections with family and friends (via phone calls, email, or video chatting) while physically socially distancing is very important. 2. Can COVID-19 be contracted from a corpse? Infection control measures should be undertaken when dealing with deceased individuals with known or suspected COVID-19. The CDCprovides guidance on this issue here: https ://www.cdc.gov / corona virus/20 l 9-ncov /hep/guidance-postmortem-specimens.html 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracting COVID-19? Clinical trials are underway to determine if hydroxychloroquine is effective in preventing COVID19 in exposed persons. Until we know the answer to this question, persons who take hydroxychloroqu ine on a daily basis for another medical condition should consider themselves vulnerable to COVID-19 and take appropriate and recommended measures to protect themselves. 4. Are masks and gloves tru ly effective, if so, why are so many medical professiona ls contracting the virus? I believe that infection control strategies which include proper use of personal protective equipment (PPE)as recommended by the CDCare effective._ https://www.cdc.gov /coronavirus /2019-ncov /hcp/infection-controlrecornmendations. h1rnl?CDC AA reNal=https% 3A %2F%2Fwww .cdc .gov%2Fcoronavirus%2F 20 l 9-ncov%2F infcction-control%2Fcontrol-recommcndations.h tml In cases where inadequate PPEis worn, or if is not put on/taken off according to proper procedure, the risk of contract ing COVID is increased. In addition, healthcare workers on the front lines can be exposed if they encounter a patient who is not initially suspected of having COVID-19 without PPE,especially if they are exposed to aerosol generating processes. 5. What is the most important thing we should be doing, other than social distancing? Social distancing is key in order to avoid coming into contact with someone with COVID-19, but washing one's hands often (or using an alchohol-based hand sanitizer) and avoiding touching one's face with unwashed hands are critical as well, especially when coming into contact with surfaces that may have been touched by others or public places. 6. Finally, wh at keeps you up at night; regarding COVID-·19? I have said in the past that what keeps me up at night is the possibility of a pandemic respiratory infection . We are in that reality now, and w hat keeps me up at night is the response, a major part of which is the development of an effective vaccine and treatments for COVID-19. Best regards, Tony Anthony S . Fauci, MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It should not be used bV anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. MEDCOM (USA) Se nt: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General From: (b)(6) ------~ ----------~ (b)(6) Dr. Fauci, I am (b)(6) the antiterror ism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command . I have been in government for nearly thirty-four years, and this is new to me. I see and hear the concerns of many people . You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- -=-=-:= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to contracti ng COVID-19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls contracting the v irus? 5. What is the most important th ing we should be do ing, other than social distanc ing? Finally, what keeps you up at night, regarding COVID-19? Thank you for your time and please be safe. _____ .... r/ Antiterrorism and Insider Threat Officer Office of the Surgeon General and U.S. Army Medica l Command Mission Assurance and Protection Division Fort Sam Houston, TX 78234 Cell phone: (b)(6) (b)(6) , z (b)( s ':-'. N:-:-: IP:::: R::--:: N -:-e-:t-;: : =======--s SIPRNet: ... Cb "'>"" C6l ------------- Level I Antiterrorism Awareness Training: http ://jko. jten.mil/courses/atl1 /launch.htm l Organizational Mailbox: (b)(6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENTIALITY NOTE: This electronic transmiss ion, includi ng all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be distributed, copied or disclosed. The contents of the transmission may also be subject to intellectua l property rights and all such rights are expressly claimed and are not waived. If you received this transmission in error, please notify the sender immediately by returning the electronic transmission and then immediately delete this transm ission, including all attachments, without copying, distributing or disclosing same . "PRIVACY ACT INFORMATION " In compliance with the Privacy Act of 1974 , this information is Personal Data and must be protected from public disclosure. From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 18 Apr 2020 20:35 :32 +0000 Lerner, Andrea (NIH/N IAID) [El Conrad, Patricia (NIH/NIA ID) [E);Greg Folkers FW : Coronavirus Quest ions for th e Offic e of th e Surgeon General --------- (b)( 6) Please fa shion some responses t o his quest ions f or me t o send back t o him Thanks . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made o n behalf of the NIAID by one of its representatives. From: (b)(6)USARMY MEDCOM ---------- (USA) (b)(6)> Date: Tuesday, April 14, 2020 9:13 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Coronavir us Questions for the Office of the Surgeon General Dr. Fauci, I am (b)(6) the antiterrorism and insider threat officer for the Office of the Surgeon General (Army)/ U.S. Army Medical Command. I have been in government for nearly thirty -four years, and th is is new to me. I see and hear the concerns of many people. You are the voice of reason for mi llions of concerned citizens. I have a few quest ions for you: --- :::-c-r,= 1. How do you recommend I reassure our staff on dealing with the stressors of COVID-19? 2. Can COVID-19 be contracted from a corpse? 3. If someone has been a user of Hydroxychloroquine for years, are they susceptible to cont racti ng COVID- 19? 4. Are masks and gloves tru ly effective , if so, why are so many medical professiona ls con tracting the virus? 5. What is the most important th ing we should be doing, other t han social distancing? Finally, what keeps you up at night, regard ing COVID-19? Thank you for your time and please be safe. r/ Antite rrorism and Insider Threat Officer -----Office of the Surgeon Gene ral and U.S. Army Medica l Command CbH 6) , Mission Assurance and Protection Division Fort Sam Houston , TX 78234 Cell phone : (b)(6) z (b)(6) s ':N:'7': IP::-: R ::-: N :-:e --:t-:: =======~--IS::ISIPRNet: (b --~,,_, (6) ------------ Leve I I Antite rrorism Awareness Training: http://jko.jten .mil/courses/at! 1/launch .html Organizational Mailbox: (b)( 6) To submit contracts for AT/OPSEC review: (b)(6) "Not on My Watch" CONFIDENT IALITY NOTE : This electronic transmiss ion , including all attachments, is directed in confidence solely to the person(s) to whom it is addressed, or an authorized recipient, and may not otherwise be dist ributed, cop ied or disclosed . The contents of the tr ansmiss ion may also be subject to intellect ual property rights and all such rights are expressly claimed and are not waived . If you received this transmission in error, please notify the sender immed iately by returning the electron ic transm ission and then immediately delete this transm ission, includ ing all attachments , without copying, distribut ing or disclosing same . "PRIVACY ACT INFORMA T ION" In complianc e with the Privacy Act of 1974, th is information is Personal Data and must be protected from public disclosure . From: Date: To: Subje ct: Fauci, Anthony (NIH/NIAID ) [E] Sat, 18 Apr 2020 19:51:12 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: COVID-19 - Potential Treatment Please t ake a loo k and handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX:(301)496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Benoit Ponton Date: Friday, April 17, 2020 8:57 AM To: Fauci, Anthony (NIH/N IAID) [E] Cc: Con t act Subject: COVID-19 - Poten tia l Trea tment ------~~ Cb)(6) COVID-19 - Potentia l Treatment April 17, 2020 Nation al Institu te of Allergy and Infectious Diseases, Nationa l Inst itu tes of Health 31 Center Drive MSC 2520 Building 31, Room 7A03 Bethesda , MD 20892-2520 C/0 Anthony S. Fauci, M .D. Hello Dr. Fauci, (b)(6) In the current state of medical knowledge and research in the pharmaceutical industry, there is no short- or medium-term solution to prevent disease or cure patients with SARS-Cov-2(COVID19). With this letter, I would like to make you aware of the preventive and curative potential of essential oils (EOs); lives could be saved. Scient ific aromather apy: use of aromatic compounds extracted from plants - essential oils - for medical purposes; 'hard' science of nature, based among other things, on in-depth knowledge of organic chemistry. We are not talking about perfumery or occult sciences. According to Mr . Dominique BAUDOUX,an internationally known Belgian pharmacist and "a romatologist": there is a multitude of research on the antiviral properties of essential oils. The results are impressive and indisputable . Here are some viruses for which we have real data: ■ ■ ■ ■ ■ ■ ■ ■ Severe acute respiratory syndrome virus SARS-Cov(it is a coronavirus) The H1Nl flu virus Avian influenza virus type H5Nl and subtypes H7N3 and H9N2 The anti-infectious bronchitis virus (IBV) Herpes simplex virus HSV Dengue virus DEN Newcastle disease virus NOV Junin virus (an arena virus responsible for hemorrhagic fever) Source: https://www.pranarom.com/blog/guide-des-huiles-essentielles/les-huiles-essentiellesefficaces-contre-lecoronavirus-vrai-ou-faux : See references 1 to 28 below . To add meat to the bone, if you visit the Nation al Cent er for Biotechnology Information (U.S.) : ■ You will find nearly 225 000 references on "essential oil." ■ See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil You will find approximately 22 000 references on "essential oil+ viral." See: https://www.ncbi.nlm.nih.gov/search/all/?term=essential%20oil%20+%20viral In addition, according to a brief email exchange with Mr. Pierre FRANCHOMME,a French researcher, one of the leading experts in the field of medicinal essential oils, he informed me that : a recent Indian study (March 31) highlights the potential activity of 1,8 cineo/e (euca/yptol) on SARS-Cov-2, as I suspected from my experience on other enveloped viruses. Note: the molecule 1,8 cineole is found in high concentration in eucalyptus EOs. ■ Sharma, A.D.; Kaur, I. Eucalyptol {1,8 cineole ) fr om Eucalyptus Essenti al Oil a Pot ential Inh ibitor of COVID 19 Corona Viru s Infection by Mol ecular Docking Studi es . Preprints 2020, 2020030455 (doi: 10.20944/preprints202003.0455.vl). Source : https://www.preprints.org/manuscript/202003.0455/vl Another study (2008) provided by Mr. Franchomme, shows a high antiviral activity of bay laurel/leaf essential oil (Lourusnobilis)on SARS-Cov,which appeared in Nov ember 2002 in Guangdong province, China and which prevailed until 2004. • Loizzo, M. R., Saab, A. M ., Tundis, R., Statti , G. A., Menichini , F., Lampront i, I., ... Doerr , H. W. (2008) . Phytochemical Analysis and in vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species. Chem ist ry & Biodivers ity, 5(3), 461 -470 . doi :10.1002/cbdv.20089 0045 Source: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 Since SARS-Covand SARS-Cov-2 {COVID-19) are close relatives, it is quite possible that Laurus nobilisessential oil will be as effective on SARS-Cov-2. Here are two other studies that should be of interest to researc hers, according to Mr. FRANCHOMME : • See reference 20 below Efficacy of cineole in patients suffering from acute bronchitis: a placebo-controlled double-blind trial. Cough 9, 25 (2013) . Source: https://doi.org/10.1186/1745-9974-9-25 Conclusions of this study : The effects of Cineole in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days. This study corroborates the fact that cineole actively and significantly reduces cough frequency after four days. Therefore it has been shown to have a great socioeconomic impact. • See also refere nce 22 below. Also, according to Mr. FRANCHOMME, a clinical study on the treatment of essential oils in patients with COVID-19 has just been undertaken in a hospital setting (100 patients), double blind against placebo . I w ill kno w th e results at the same time as everyo ne else and will inform you. Here is a summary of Mr. FRANCHOMME's analysis: (b) (4) The scientific commun ity is launc necl in searc no f a m iradeclru g in t he basket of molecu es already known for ot he r i ndicat io ns. Our design is to t rust the plant world, a great provider of remarkable mo lecules. CONCLUSION We need to think outside the box of allopath ic medicine and synthetic drugs that offer no solution and put pre ssure on our leaders to release funds for clinical research on the treatment of patients suffe rin g from COVID-19 using essential oils, as advocated by Mr . Franchomme . To this end, M. FRANCHOMME confirmed to me this : / am at the disposal of your authorities to provide and explain a protocol based on essential oils. His email address is : (b)(6) In terms of a double-blind placebo clinical study, there is, as of today, a huge cohort of hospitalized pat ients, a significant portion of whom I suspect would be enthusiast ic about voluntary enrolment. For pat ients in critical care with a life-threatening prognosis, it is undoubtedly possible, given the circumstances , to bypass the usual research protocols and offer a last-resort treatment to these patients in an attempt to save their lives, with thei r permission or that of their legal representatives in case of temporary or permanent incapacity . Even if it doesn't work, I don't think patients or their loved ones will blame your government for trying everything , but if you don't, I wouldn't like to be in your shoes! Cordially, Benoit Ponton BP/bp CC: M. Pierre FRANCHOMME 2150, rue Marianne-Baby Chambly, QC, Canada J3L OA3 Off ice (450) 447-4872 Cell phone (b) (6) Email bponton@cpa-qc.ca SCIENTIFICPUBLICATIONS Source : https ://www . pra narom.com/blog/guide-des-h u iles-essentielles/ les-hui les-essentiellesefficaces-contre-1 ecoronavi rus-vrai-ou-fa ux 1. Garozzo, A., Timpanaro, R., Bisignano, B., Furneri, P. M., Bisignano, G., & Castro, A. (2009). In vitro antiviral activity of Melaleuca alternifolia essential oil. Letters in applied microbiology, 49(6), 806-808. https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1472765X.2009.027 40.x 2. Reichling, J., Schnitzler, P., Suschke, U., & Saller, R. (2009). Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties-an overview . Complementary Medicine Research, 16(2), 79-90. https://www.karger.com/Article/Abstract/207196 3. Schnit zler, P., Schon, K. and Reichling, J. (2001) Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture . Pharmazie 56, 343347. https://www.ncbi.nlm.nih.gov/pubmed/11338678 4. Mohammad, A., & Mehmood, D.ln Vivo Anti-Viral Effect of Melaleuca alternifolia (Tea Tree Oil) and Olea europ aea (Olive Leaf Extract) on Vero Cell Adapted Avian Influenz a Virus. Human Journals . Research Article December 2018 Vol.:14, lssue:1 Citation : Mohammad Danish Mehmoo d et al. ljppr.Human , 2018; Vol. 14 (1): 7-19. https://www.researchgate .net/publication/331149520 In Vivo AntiViral Effect of Melaleuca alternifolia Tea Tree Oil and Olea europaea Olive Leaf Extract on Vero Cell Adapted Avian Influenza Virus 5. Usachev, E. V., Pyankov, 0. V., Usacheva, 0. V., & Agranovski, I. E. (2013). Antiviral activity of te a tr ee and eucalyptu s oil aerosol a nd vapour . Journal of aerosol science, 59, 22-30. https://www.sciencedirect.com/science/article/pii/S0021850213000086 6. Ank ita, S., Chandra, S.S., & Arti, T. (2013). Phytochemic al study and antimicrob ial activities of cinnamomum camphora . Wo rld Journa l of Pharmaceutic al research Volume 3, Issue 2, 2287-2294. https://www.google .com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wildfj5OHoAhUEZN8KHZDjBdMQFjABegQIBBAB&url=https%3A%2F%2Fwjpr .net%2Fdow nload%2Farticle%2F1400323946 .pdf&usg=AOvVaw0WLdK22ogsjVQCt6bgmXeb 7. Astani, A., & Schnit zler, P. (2014). Antiviral activity of monot erpenes beta-pinen e and limon ene against herpe s simplex virus in vitro. Iranian journal of microbio logy, 6(3), 149. https://www.ncbi.nlm .nih .gov/pmc/articles/PMC4393490/ 8. Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research: An Internationa l Journal Devoted to Pharmacological and Toxico logical Evaluation of Natural Product Derivatives, 24(5), 673-679 . https://onlinelibrary.wiley .com/doi/abs/10 .1002/ptr.2955 9. Bisignano, B. (2009) . Attivit a antivirale e studio del meccanismo d'azione di estratti di melaleuca alternifolia nei vonfronti del viru s dell'influenza A. Area 06 - Scienze mediche. http://hdl. hand le .net/10761/1767 10. Blanchard, J. M . (2007). Cinnamomum camphora a cineole (ravintsara), une plante au service de la prevention des infection s nosocomiales en milieu hospitalier ?. Phytotherap ie, 5(1), 15-20. 11. Carson, C.F., Ashton, L., Dry, L., Smith, D.W . and Riley, T.V. (2001) Melal euca alternifolia (tea tree) oil gel (6%} for the treatment of recurrent herpes labial is. J Ant imicrob Chemother 48, 450- 451. https://academic.oup.com/jac/article/48/3/450/736091 12. Carson, C.F., Smith, D.W., Lampacher, G.J. and Riley, T.V. (2008) Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialis. Contemp Clin Trials 29, 9-12. https ://www .contem pora rycli nica Itri als. com/ art icle/S1551- 7144( 07 )00053-5/ful Itext 13. Galan, D. M ., Ezeudu, N. E., ..., & Ma lcolm, B. J. (2020) . Eucalyptol (1, 8-cineole) : an underutilized ally in respiratory disorders?. Journa l of Essential Oil Research, 1-8. https://www.tandfonline.com/doi/abs/10.1080/10412905.2020.1716867?journa1Code= tjeo20 14. Garozzo, A., Timpanaro, R., Stivala, A., Bisignano, G., & Castro, A. (2011). Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action . Antiviral research, 89(1), 83-88. https:ljwww.sciencedirect.com/science/article/abs/pii/50166354210008120?via%3Dih ub 15. Hamidpour, R., Hamidpour, S., Hamidpour, M., & Shahlari, M . (201 4) . Chemistry, Pharmacology and Medicinal Property of Camphor (Cinnamomum Camphora) Traditional Remedy with the History of Treating Several Diseases. Global Journal of Medical Research. https://scholar.google.com/citations?user=xrGgDigAAAAJ&hl=en 16. Jean Michel Blanchard (2007 ). Cinnamomum camphora CT cineole (ravintsara), a plant to help prevent nosocomial infections in the hospital environment. Inte rnational Journa l of Clinical Aromatherapy Vol. 4 issue 1 17. Li, X., Duan, S., Chu, C., Xu, J., Zeng, G., Lam, A. K. Y., ... & Gu, H. (2013). Melaleuca alternifolia concentrate inhibits in vitro entry of influenza virus into host cells. Mo lecule s, 18(8), 9550-9566. https://www.mdpi.com/1420-3049/18/8/9550 18. Li, Y., Xu, Y. L., ... & Xu, P. P. (2017). Intranasal co-administration of 1, 8-cineole with influenza vaccine provide cross-protection against influenza virus infection . Phytomedicine, 34, 127-135. https://www.sciencedirect.com/science/article/abs/pii/50944 711317301034 ?via%3Dih ub 19. Loizzo, M. R., Saab, A. M ., Tundis, R., Statti, G. A., Menichini, F., Lampront i, I., ... & Doerr, H. W. (2008) . Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chemistry & biodiversity, 5(3), 461-470. https://onlinelibrary.wiley.com/doi/abs/10.1002/cbdv.200890045 20. Mansard, M., Laurain-Mattar, D., & Couic-Marin ier, F. (2019). Huile essentielle de Ravintsara. Actualites Pharma ceutiques, 58(585), 57-59. https://www.sciencedirect.com/science/article/pii/S0515370019300734?via%3Dihub 21. Morales - Rico, C. L., ... & Gonzalez -Camejo, I. (2012).Composicion qu1mica del aceite esencial de las partes aereas de Melaleuca quinquenervia. Revista CENIC. Ciencias Qufmicas , 43, 1-2. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=2ahUKE wig4qLa7uHoAhWhnuAKHSDZAasQFjABegQIAhAB&url=http%3A%2F%2Fwww.revistas.u sach.cl%2Fojs%2Findex.php%2Fblacpma%2Farticle%2Fdownload%2F2401%2F2210%2F & usg=AOvVaw3k2 Urazeofgeg ftc 7wd K 22. Janine Muller, Johannes F.W. Greiner, Mar ie Zeuner, Viktor ia Brotzmann, Johanna Schafermann, Frederique Wieters, Darius Widera, Holger Sudhoff, Barbara Kaltschmidt, Christian Kaltschmidt; Clin Sci (Lond) 1 August 2016; 130 (15): 1339- 1352. 1, 8-Cineole potenti ate s IRF3-mediated antiviral response in human stem cells and in an ex vivo mod el of rhinosinusitis. Clinical Science (Lond) 1 August 2016; 130 (15): 1339-135 2. https://doi.org/10.1042/CS20160218 et https://portlandpress.com/clinsci/articleabstract/130/15/1339/71448/1-8-Cineole-potentiates-lRF3mediatedantiviral?redirectedFrom=fulltext 23. Riley, T. V. (2005). Antivir al Activity of Tea Tree Oil-In Vitro and In Vivo . TV Riley-2005 - academia.edu https:ljwww .agrifutures.eom.au/product/antiviral -activity-of -tea-treeoil-in-vitro-and-in-vivo/ 24. Siddique , S., et al. (2018) . Chemical characterization , antioxidant and antimicrobial activiti es of essential oil from M elaleuca quinqu enervia leaves. Indian Journa l of Experimen t al Biology, 56, 686-693 . https:ljwww.researchgate.net/publ ication/327829462 Chemical characterization anti oxidant and antimicrobial activities of essential oil from Melaleuca guinguenervia leaves 25. Timpana ro, R., Garozzo, A., Bisignano, B., Stivala, A., Furneri, P. M ., Temp era, G., & Cast ro, A. (2007) . Inhibitory effect of Melaleuca alternifolia (tea tree oil) on influenza A/PR/8 viru s replication . Internatio nal Journa l of Ant imicrobial Agents, (29), S202-S203. https://www.sciencedirect.com/science/article/abs/pii/S0166354210008120?via%3Dih ub 26. Worth, H., ..& Deth lefsen, U. (2009). Concomitant therapy with Cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled doubleblind trial. Respiratory research, 10(1), 69. https://respiratoryresearch.biomedcentral.com/articles/10.1186/1465-9921-10-69 27. Yang, Z., Wu, N., .. & Efferth, T. (2010). Anti-infectious bronchitis virus (IBV) activity of 1, 8-cineole: Effect on nucleocapsid (N) protein . Journal of Biomolecu lar Structu re and Dynamics, 28(3), 323-330. https://www.tandfonline .com/doi/abs/10.1080/07391102.2010 .10507362 28. Zamora, A. C. P. (2015). The Antiviral Properties of Mela leuca alternifolia concentrate (MAC) against West Nile virus (Doctoral dissertation, Griffith University). https://pdfs.semanticscholar.org/fc36/83837c5d872444e51c452bdd3f6a644fa079.pdf OTHER SCIENTIFICPUBLICATIONS Source : https://www.aude-maillard.fr/4-huiles-essentielles-contre -le-coronavirus/ 29. Brun, P., Bernabe, G., Filippini, R. et al. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca a/ternifolia) Essential Oils. CurrMicrobial 76, 108-116 (2019) . https ://doi.org/10.1007 /s00284-018-1594-x 30. Shih-Yu Lee, Po-Yu Chen, Jung-Chun Lin, Nicholas S. Kirkby, Ching-Huei Ou and TsuChung Chang Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264 .7 Cells through Activation of the Nrf2-ARE Pathway . The American Journal of Chinese Med icineVol. 45, No. 08, pp. 1631-1648 {2017) https://doi .org/10.1142/S0192415Xl 7500872 31. Akram Astani, Jurgen Reichling and Paul Schnitzler. Screening for antiviral activities of isolated compounds from essential oils. Hindawi. Evidence-Based Complementary and Alternative M edicine/ 2011 https://doi.org/10.1093/ecam/nep187 32. Schnitzler P. Essential Oils for the Treatment of Herpes Simplex Viru s Infection s. Chemotherapy 2019;64 :l-7. https://doi.org/10.1159/000501062 CONFIDENTIALITY NOTICE: The information contained in this transm ission {including any files attached to it) is legally privileged and confidential and is intended solely for the use of the individual or entity to whom it is addressed. Any other use, dissemination, distribution, disclosure or copying of this message is strictly prohibited. If you have received this commun ication in error, please immediately notify the sender so that we may ensure the intended recipient receives a copy of the origina l transm ission. We then ask that you kindly destroy your copy and delete the ent ire message from your computer system. AV IS DE CONFIDENTIALITE: L'information contenue dans cette transm ission {et tout document ci-jo int) est confidentie Ile et privilegiee et est !'usage exclusif de la personne ou de l'entite qui elle est adressee. Tout autre usage, distribut ion, divulgat ion, ou cop ie de cette communication est strictement prohibe. Si vous avez re~u cette transmission par erreur, veuillez nous en aviser immediatement pour que nous puissions envoyer le message au destinataire. Aussi, nous vous demandons de detruire toutes les copies et le supprimer de votre systeme informatique. a a From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:46 :44 +0000 Del Rio, Carlos RE:released. Than ks, Carlos. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Del Rio, Carlos (b)(6)> Date: Friday, April 17, 2020 11 :16 AM To: 'Birx, Deborah L. EOP/NSC' ---------- (b)( 6) ------------.,.....,..= -----------(b)( Cc: Rochelle Walensky MD, MPH Subject: released. ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Here is link to the paper ent itled "From Mit igat io n to Conta inment of the COVID-19 Pandemic- Putting th e SARS-CoV-2Genie Back in t he Bott le" that Rochelle and I wrote for JAMA. Hope you fi nd it useful. Feel free to d istribute . Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fulla rticle/2764956 Sincerely, Carlos This e-mail message (including any attachments ) is 'or the sole use of the intended rectpient(s) and may contain confidential and privileged Information. If the reader of this message 1s not the intended recipient, you are hereby notified !hat any dissemination distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:40 :55 +0000 Walensky, Rochelle,M .D.,M .P.H. RE:released . Thanks, Rochelle! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Walens ky, Rochelle,M.D .,M .P.H. (b)(6)> Se nt : Friday, April 17, 2020 11:54 AM To: Carlos del Rio (b)(6)> ; 'Birx, Deborah L. EOP/NSC' Fauci, Anthony (NIH/NIAID) [E) CbH61> Subject: RE: released. ----------- Dear Ors. Birx and Fauci (Debbie and Tony, if I may), So grateful for all you are doing. Please let us know if there is any way we can help. My best from Boston, Rochelle Rochelle P. Walensky, MD, MPH Chief, Division of Infectious Diseases Steve and Deborah Gorlin MGH Research Scholar Massachusetts General Hospital Division of Infect ious Disease Professor, Harvard Medical School 55 Fruit Street, GRJ504J floor Boston, MA 02114-2696 Phone: (b)(6) Fax: 617-726-7416 Email: Pronouns: she/her/hers ----------- (b)(6) (b)(6) ; From: Del Rio, Carlos _________ Cb _) _(6) ... ) Date: Friday, April 17, 2020 11:16 AM ----------~= ------------ To: 'Birx, Deborah L. EOP/NSC' (b) (6)> Cc: Walensky,Rochelle,M.D.,M.P.H.__________ Subject: released. (b)( >; 'Fauci, Anthony (NIH/NIAID) [E)' Cb _)_C_ > External Email - Use Caution Here is link to the paper entitled "From Mitigation to Containment of the COVID-19 Pandemic- Putting the SARS-CoV-2Genie Back in the Bottle" that Rochelle and I wrote for JAMA . Hope you find it useful. Feel free to distribute. Thanks again for all you are doing! https://jamanetwork.com/journals/jama/fullarticle/2764956 Sincerely, Carlos This e-mail message (including any anachmems) is 'or the sole use of the intended recipient(s) and may contain confidential and privileged infonnation. If the reader of this message is not the intended recipient, you are hereby notified that any disseminat ion distribution or copying of this message (including any attachmerts) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments) Th e information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient infonnation, please contact the sender and properly dispose of the e-mail. From: Date: To: Cc: [El -----~~ Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 19:34 :53 +0000 Jeffrey V. Ravetch Lusso, Paolo (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) (b)( 6) ;Cassetti, Cristina (N IH/NIAID) [El; Erb elding, Emi ly (NIH/N IAID) [El FW: new manusc ript Bournazos, et al.docx, Extended Figures .pdf Jeff: Very interesting paper. Could have wide applicability in viral disease. I will pass it on to our program people. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----------------~~ --------- From: Jeffrey V. Ravetch Date: Friday, Apri l 17, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: new manuscript (b)(6)> (b)(6) Tony, I've attached a pre-pr int of the story I briefly told you about related to Fe optim ization of anti-v iral ant ibod ies to induce CD8 protective responses. I'd be grate ful fo r your comments. And my sincere grat it ude for keeping science at the front of th is pandemic. Best regards, From: Date: To: Cc: [E______ Subject: Attachments: Fauci, Anthony {NIH/NIAID) [E] Sat, 18 Apr 2020 19:30:56 +0000 Lerner, Andrea {NIH/NIAID) [E] Conrad, Patricia {NIH/NIAID) [E]; Cassetti, Cristina {NIH/NIAID) (b :::-: ),..,. (6) = FW: Concept Paper for NEJM on Novel Clinical Trial in COVID-19 Composite EPOCOVID-19.pdf Andrea : This is a former post-doc in my lab. Please read this, get back to her apologizing Cb> cs> I that I could not respond 0 bvi o usIy can have no part in it. Thanks, ----------------------- Tony Anthony S. Fauci, MO Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: Cb)(6) FAX: {301 496-4409 E-mail: (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Ehrenreich, Hannelore (b)( > Date: Friday, April 17, 2020 1:46 PM To: Fauci, Anthony (NIH/NIAID ) [E] (b)(6) Subject: Concept Paper for NEJM on Novel Clin ical Trial in COVID-19 ------~= Dear Tony, I am aware of the heavy load that is on your shoulders these days but I sincerely hope to get a brief answer to my E-mail. In light of the present therapeutic situation in COVID-19, any measure to improve course and outcome of seriously affected individuals is of utmost importance. In the attached (b) (6), (b) (4) (b) (6), (b) (4) We all would be extremely grateful for your feedback and for your collaboration! In fact, I personally would be so proud to have you as senior coauthor as in former times! Please let me know what you think. We could also discuss over the phone if you let me know which time would be convenient. All my best , Hannelore -----Ursprungliche Nachricht----Von : Ehrenreich, Hannelore Gesendet: Samstag, 21. Marz 2020 13:24 An: 'Fauci, Anthony (NIH/NIAID) [E]' Betreff: THANK YOU from Germany ------~= Dear Tony, (b)(6)> J I I I ~n?w you are extremely busy these days... now even more than befo Jil dOe to this ter:ribi ~ ~rona cns1s! II" [J Just a brief note to let you know that I watched your excellent interviews and that I am extremely proud of you! For people here in our Max Planck Institute and the many biomedical institutions in Gottingen you are the greatest hero indeed in a tough time ... I wish you all strength and endurance needed to lead the world out of this crisis (despite questionable politicians)! STAY HEALTHY! All my best, Hannelore Professor Hannelore Ehrenreich, MD, DVM Clinical Neuroscience Max Planck Inst it ute of Experimental Medicine Hermann-Rein-Str.3 37075 Gott ingen GERMANY Tel : (b)( Fax: 49-551-3899 670 (b)(6) E-Mai l: Prof. hon . Univer sity of Gott ingen Faculty of Biology & Psychology --------- From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [E) Sat, 18 Apr 2020 19:21 :39 +0000 Stover, Kathy (NIH/NIAID ) [E) Billet, Courtney (NIH/ NIAID) [El;Folkers, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/N IAID) [El Subject: RE: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strategic Research Plan Looks fin e. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/N IAID) [El (b)( 6)r> Date: Friday, April 17, 2020 2:42 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Billet, Courtney {NIH/NIAID) [El (b)(6)>; Folkers, Greg (NIH/NIAID) [El _______ Cb H_ >; Conrad, Patricia (NIH/NIAID) [E) _ (b)(6)> ------ ::;..,..-,= Subject: FOR ASF REVIEW: Draft MA re: NIAID COVID 19 Strateg ic Research Plan Hi Dr. Fauci, Please find attached for your review a draft media availability about NIAi D's COVID-19 strateg ic research plan . We've named you as t he spokesperson in the med ia avail. Best, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Institute of Allergy and Infectious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) E-mail: (b)(6) NIAID Media Line: (301) 402-1663 From: Date: To: ------- Robert (OS/ASPR/10) Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:30 :03 +0000 Hahn, Stephe n;Birx, Deborah L. EOP/NSC;Redfield, Robert R. (CDC/OD);Kadlec, (bH · FW: Boston Globe: Nearly a t hird of 200 blood samp les taken in Chelsea show exposure to coronavirus St eve : (b)(5) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Inst itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/N IAID) [E] (b)(6) Date: Saturday, Apr il 18, 2020 1:54 PM Subject: Boston Glob e: Nearly a th ird of 200 blood sam ples t aken in Chelsea show exposu re t o coronavirus Nearly a third of 200 blood samples taken in Chelsea show exposure to coronavirus Mass. General researcher says the results point to a 'raging epidemic,' but may also indicate the city is further along the disease curve than some other municipalities ByJonathan Saltzman Globe Staff,Updated Apr il 17, 2020, 6:26 p.m. First responders loaded a patient into an ambulance from a nursing home whe re multiple people have contracted COID-19 in Chelsea, which has the highest concentration of COVID-19 infections in the state.Scott Eisen/Getty Nearly one third of 200 Chelsea residents who gave a drop of blood to researchers on the street this week tested positive for antibodies linked to COVID-19, a startling indication of how widespread infections have been in the densely populated city. Sixty-four residents who had a finger pricked in Bellingham Square on Tuesday and Wednesday had antibod ies that the immune system makes to fight off the coronavirus, according to Massachusetts General Hospital physicians who ran the pilot study . The 200 participants generally appeared healthy, but about half told the doctors they had had at least one symptom of COVID-19 in t he past four weeks. Public health experts already knew Chelsea hadthe state's highest rate of con fir med COVID-19 cases and that the actua l rate was probably higher . At least 39 residents have died from the virus, and 712 had tested positive as of Tuesday, a rate of about 1,900 cases per 100,000 residents, or almost 2 percent . Get Talking Points in your inboxAn afternoon recap of the day's most important business news, delivered Monday through Friday. But the Mass. General researchers - who excluded anyone who had tested positive for the virus in the standard nasal swab test - found that 32 percent of participants have had COVID-19, and many didn't know it . "I think it 's both good news and bad news," said Dr. John Iafrate, vice chairman of MGH's pathology department and the study's principal investigator. 11The bad news is that there's a raging epidem ic in Chelsea, and many people walking on the street don't know that they're carrying the virus and that they may be exposing uninfected individuals in their families ." "On the good-news side, it suggests that Chelsea has made its way through a good part of the epidemic," he said. "They're probably further along than other towns." Scientists suspect that people who recover from COVID-19 may be at least temporarily immune from catching it again. Several biotechs and academic laboratories, in fact , are seeking blood do nations from people who have recovered, in the hopes that their antibodies can help create a treatment or vaccine. Chelsea's city manager, Thomas Ambrosino, said he learned the results of the pilot study Thursday in a conference call with the researchers. He was dismayed, but not shocked. Related: Chelsea city manager sounds urgent alarm, calls for residents to stay home 24 hours a day "We've long thought that the reported numbers are vastly unde r-counting what the actual infection is," said Ambrosino, w ho has called his city the epicenter of the crisis in Massachusetts. "Those reported numbers are based on positive COVID-19 tests, and we're all aware that a very, very small percentage of people in Chelsea and everywhere are getting COVID-19 tests." "Still," he added, "it's kind of sobering that 30 percent of a random group of 200 people that are showing no symptoms are, in fact, infected. It's all the more reason for everyone to be practicing physical distancing." Indeed, one of the doctors who tested volunteers in Bellingham Square said it's possible that some of the people who had the antibodies are still contagious. "Just because you have the antibodies doesn't mean you've cleared the virus," said Dr. Vivek Naranbhai, a clinical fellow in hematology and oncology. Researchers said the test results, which had yet to be shared with state officials late Friday, couldn't necessarily be extrapolated for the city's roughly 40,000 residents. Still, the findings provided a valuable snapshot of a community that medical experts say is especially vulnerable to COVID-19. Chelsea covers only about two square miles, across the Mystic River from Boston. For generations, it has attracted new immigrants, and about 65 percent of its residents are Latino. Many live in three-decker houses, Ambrosino said, where it's hard for people to isolate themselves. Many work in the hospitality industry and health-related fields, where exposure to the virus is greater. And a lot of them must go to work during the pandemic. To get Chelsea residents to participate in the study - which included a questionnaire that was available in English, Spanish, and Portuguese - investigators allowed them to remain anonymous. But that meant none of the participants received the results of the blood tests. The doctors used a diagnostic device made by BioMedomics, of Morrisville, N.C., to analyze drops of blood. It resembled an over-the-counter pregnancy test and generated results on the street in about 10 minutes. Although the test hasn't won the approval of the Food and Drug Administration, Iafrate, the principal investigator, said Mass. General determined it's reliable. Within days, the physicians said, they hope to set up a medical tent outside the Mass. General Chelsea Healthcare Center to perform more antibodies tests with the device. The site will be located near a tent set up weeks ago to run standard PCR,or polymerase chain reaction, tests for people with active coronavirus symptoms. The latter uses nasal swabs to detect whether the virus is present at the time; the antibodies blood test reveals whether someone was infected in the past. In addition to the new testing site, the researchers want to expand the study to other Massachusetts cities and towns. For all of those studies, Mass. General doctors plan to obtain the identities of participants so physicians can provide the results. But first the researchers need to come up with guidelines for what participants should do if they test positive for antibodies. Dr. Dean Xerras, medical director of the Mass. General Chelsea Healthcare Center and a co-investigator in the study, said it illustrates why it's essential for Chelsea and other communities to perform more tests, regardless of whether they detect antibodies or the virus itself. "Knowing how many people are infected is critical," said Xerras, a longtime member of the city's board of health. "We need to get them isolated. We need to get masks delivered to the city. We need to launch more safe isolation sites. We need to be able to identify cases and then give people the things they need to prevent perpetuation of the spread." Chelsea and Revere officials, with help from the state Department of Public Health and the Massachusetts Emergency Management Agency, secured almost 150 rooms at a Quality Inn in Revere this week for residents who are recovering from COVID-19 and unable to isolate themselves at home, according to Ambrosino. So far, only a handful of those rooms are occupied. Governor Charlie Baker on Thursday staunch ly defended the state ' s handling of the escalating outbreak in Chelsea, including asserting, without offering details, that city leaders have turned down help from his administration. The governor's claim surprised officials in Chelsea who told the Globe this week that the state, and even health care providers, should have recognized the virus's rapid spread through the city sooner. Jonathan Saltzman can be reached at jonathan .saltzman@globe.com Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNTAID, NIH, HHS, or the U.S. government. From: Date: (b)(6) To: Subject: Attachments : Sat, 18 Apr 2020 12:28 :50 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: working draft of NEJM COVID vaccine editorial _ 16April 7pm.docx, ATT00001.htm Sent from my iPhone Begin forwarded message: From: "Corey MD, Lany" (b)( ·> Date: April 18, 2020 at 12:34:13 AM ED T To: "Conrad, Patricia (NIH/NIAID) [E]" Anthony (NIH/NIA ID) [E]" ___ (bH .___~~ Cc: "Mascola, John (NIHNRC) [E]" _______ ---------=-:-:-="Fauci, (b)(6) >, (b_H_6) Subject: working draft of NEJM Here is the working draft . My manuscript typist too tired to work tonight so it reflects several changes I made tonight ; it should be readable; Larry From: Date: (b)(6) Sat, 18 Apr 2020 12:27:56 -0400 Fauci, Anthony (NIH/NIAID) [E) Fwd: JAMA- Heroes heroes. pdf, ATT00001.htm To: Subject: Attachments : Sent from my iPhone Begin forwarded message: From: Howard Bauchner Date: April 18, 2020 at 5:10: 15 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Cc: Phil Fontanarosa Subject: JAMA - Heroes --------=-=-= There are many many heroes in this tragedy - but none more so than you, Maurizio, and Dr. Wenilang. Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats wi t h authors From: Howard Bauchner Date: Saturday, April 18, 2020 at 4:07 AM To: CECCONIHUNIMED (b)(6) Subject: Re: Hello I am well - (b)(6) - but you know --"""".""~-=--....:..------------__;;~---, all about that - remain in Chicago - at work (b =-< )=(6) - he will quarantine for the 2 weeks he is up there. Yes- NY, London, Paris - all diff icult times- great vector- the subway , underground, and metro - unmasked folks who were asymptomatic carriers -terrible. Most of t he US managing although still a heavy heavy lift in some p laces - NY, Boston, some in Chicago - but most of the US managing. The big issue like everywhere is how do we put society back toget her . Will be published on Monday- our tr ibute to many peop le and 3 individua ls. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Networ k Please respect the confide ntial ity of this emai l Listen to my chats with authors From: CECCONI HUN IMED ------------- (b)(6)> Date: Friday, April 17, 2020 at 2:07 PM To: Howard Bauchn e r Subject: Hello [Warning External Email] Hello Howard, I hope you are well. Just a line to say that the podcasts are incredible. I hope you are ok. I am very sorry for the colleagues in New York. I know it's very tough t here and also in other parts of US. Things are getting better here. Keep up the amazing work. Kind regards, Mau ri zio Mau ri zio Cecconi MD FRCAFFICM MD(Res) Head of Department Anaesthe sia and Inte nsive Care Units Human itas Research Hospital Professor of Anaesthesia and Intensive Care Humanitas University President Elect ESICM Nota ai riservatezza 11pre5ente messaggio, corredato deI relativi allegati, contIene lnforma.:ionl da considerarsI strettamentc riservate, ed destinato esclusIvamente al destmatarlo sopra ind1cato, ii quale l'unico autoriz.zato ad usarlo, cop1arlo e, sotto la propna responsabillta, d1ffonderlo. Ch1unque ricevesse questo messaggI0 per errore o comunque lo leggesse senza esserne ieg1tt1mato e avvertIto che trattenerlo, copIarI0. divuigarlo, dIstribuirlo a persone diverse dal destinatarlo severament.e proibito, ed pregato di rinviarlo 1mmedlatamente al mltter1le distruggendone l'or19Inale. Grazie Conf1dent1allty Notice Tl1Is message, together wltl1 its annexes, contains Informat1on to be deemed smctly confidential and is destined only to th,• addressee(s) identified above wl10 only ma., use, copy and, under l1is/tl1eir responsibility, furl11er disseminate it. If anyone, received this message by mistake or reads It without entitlement Is forewarned that keeping, copying, disseminating or distributing this message to persons other than the addressee(s) ,s strictly forbidden and Is asked to transmit 1t 1rnmed1ately to thci sender and to erase the ongmal message received e e e Thank You e From: Date: Fauci, Anthony (NIH/NIAID) [El Sat, 18 Apr 2020 13:46:56 +0000 Greg Folkers To: CbH6);Morens,David (NIH/NIAID) [El FW: CDC:---------------------- Cb)(5) https://bit .ly/2Ki5Ry4 (b) (5) We really need to talk about this. --------- From: Morens, David (NIH/NIAID) [E] Date: Friday, April 17, 2020 6:49 PM To: Folkers, Greg (NIH/NIAID) [El -----~ Cc: NIAID OD AM Subject: Re: CDC: (b)(6) Cb H= > ~ (b)(5 https://bit.ly/2Ki5Ry4 (b) (5) Sent from my iPhone David M Mo rens OD, NIAID, NIH On Apr 17, 2020, at 18:30, Folkers, Greg (NIH/NIAID) [El -------- (b)(6) wrote: (b) (5) The estimates on this page have been updated from an earlier report published in December 2018 based on more recently available information. There is a trade-off between timeliness and accuracy of the burden estimates. To provide timely burden estimates to the public, clinicians, and publ ic health decision-makers, we use preliminary data that may lead to over- or under-estimates of the true burden. However, each season's estimates will be finalized when data on testing practices and deaths for that season are available. For the revised 2017-2018 estimates, we included additional information in our estimation regarding influenza testing practices. The surveil lance system used to estimate influenzarelated hospitalizations, FluSurv-NET,collects data on patients hospitalized with laboratory-confirmed influenza. Influenza testing is done at the request of the clinician, but not everyone is tested and influenza tests are not perfectly accurate. Thus, the reports of laboratory-confirmed influenza-related hospitalizations to FluSurv-NETare likely underestimates of the true number of hospitalizations. To adjust for this, CDCcollects data annually from participating FluSurv-NET sites on the amount of influenza testing and the type of test that is used at the site, and this information is used to correct for the possible underestimate of influenza-related hospitalizations . These testing data are often not available for up to two years after the end of an influenza season, and thus the estimates are revised when additional testing data become available . For the orig inal preliminary 2017-2018 burden estimates, data on testing practices during the 2014-2015 season were used to make preliminary estimates because this season had the highest levels of testing among the prior seasons for which data were available and resulted in the most conservative (lowest) estimates of burden. More recent data from the 2016-17 season show that influenza testing has been increasing among most age groups. The current estimates were made using the highest testing rate fo r each age-group during 2010-11 to 2016-17 and has resulted in some burden estimates being lower than previously estimated. Additionally, the method we use to estimate influenza -associated deaths relies on additional data from FluSurv-NH and the National Center for Health Statistics (data on cause of deaths and numbers of deaths that occur in versus outside the hospital) that are also not available for up to two years after the end of the season being estimated . The 2017-2018 estimates are still preliminary because not all of the required data are currently available. When those data become available, these estimates will be updated again and the results may change. More answers to frequently asked questions about CDC's influenza burden estimates are available. Disclaimer: Any third-party mat erial in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity. It does not necessarily represent my views nor tho se of NlAlD , NlH , HHS , or the U.S. government . From: Date: (b)(6) Fri, 17 Apr 2020 14:45:56-0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitation to speak at virtual TIME 100 event To: Subject: Let us make sure that we discuss this. Begin forwarded message: Fr om : Alice Park Date: April 17, 2020 at 2:07 : 17 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" -------~= (b)(6J: Cc: Cate Matthews Subject: Re: Invitation to speak at virtual TIME 100 event Hi Dr. Fauci -- I also should have added that we are happy to pre-tape the interview so it does not have to happen on April 23. ln order for it to run on that date, we would love to record it some time Wed during the day or on Thurs morning.Hoping that helps with timing, and looking forward to hearing from you. Best, Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny On Fri, Apr 17, 2020 at 9:35 AM Alice Park w rote: Dear Dr. Fauci, Thank you for making time to talk to me during the early weeks of the pandemic. I know your schedule is tight, but wanted to pass along an invitation to speak at a unique virtual summit we're holding next week, that I hope we can make work. Building on the impact of our annual TIME 100 and TIME 100 Health summits, as well as our ongoing coverage of COVID-19, on Thur sday, April 23 , TIME will launch its first-ever virtual event series, "TIME Talks: Finding Hope." Our goal is to convene a group of the world's leading voices, including TIME 100 honorees, to spotlight the important work they're doing to combat this crisis, and to help our viewers navigate this new reality. As part of our launch event , schedule d to take place between noon and 3 p.m. ET, we'd like to invite you to participate in a short, 10- to 20-minute video interview with a TIME editor on public health policies that could be implemented at the national level to strengthen the responses to this and fu ture pandemics - addressing in particular lessons learned from the initial response to the coronavirus . We would also welcome your thoughts on how we plan to navigate out of the pandemic a nd what the new normal will look like . (Please note that we are open to discussing othe r topics as wel l.) Each conversation will be streamed and promoted across TIME 's platfo rms, which reach a comb ined audience of 100 million people around the world . As one of our invited speakers , you would also be part of an extraordinary community of leaders who are shaping our world . Past speakers at T IME events include House Speaker Nancy Pelosi , Apple CEO T im Cook , Primatologist Jan e Goodall , White House Adviser Jared Ku shner , Chef Jos e A ndres, Me Too Movement Founder Tarana Burk e, Producer Director Ryan Murphy , and many others . T hank you in adva nce for considering this invitatio n. Cate. our program coordinator . and I are happy to help with any questions you may have. Looking forward to hearing from you . Best , Alice PLEASE NOTE NEW PHONE NUMBER Alice Park TIME (b)(6) alice.park@time.com @aliceparkny Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 16:00:09 +0000 Thomas R. Frieden Re: Box It In image001.png , image002.png, image003.jpg From: Date: To: Subject: Att achments: Thanks, Tom. I totally agree with this approach. I have been trying to catch you by phone but have gotten a voicemail with a message that the mailbox is ful l. Do I have the con-ect number? Thanks, Tony On Apr 17, 2020 , at 11 :00 AM, Thomas R. Frieden (b)(6). wrote: Tony, Wishing you well. Wanted you to be aware that we're releasing a repo rt at a media briefing this morning on how to " Box in COVID." This plan includes priorit ized expansion of testing and building a corps of contact tracers in the US, using tried-and-true public health measures at scale. There are four essential actions to box in the virus: 1) Expand testing; 2) Isolate infected people to prevent spread; 3) Identify contacts who may have exposed; 4) Quarantine contacts. As you know, all four are crucial; if any one is lacking, the virus can escape and spread explosively again. Success requires a massive expansion of our public health capacity around the country and world. The report is attached and can be downloaded here . Please let me know how we can continue to be as supportive as possible. All the best, Tom Tom Friede n, MD, MPH President and CEO www.DrTomFrieden.net (b)(6) RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org face book twitter ~ TOSAVE LIVES AHINITIATIVE OFVITAL STRATEG From: Date: To: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 10:15:13 +0000 Lerner, Andrea (NIH/N IAID) [El FW: (b)(4) Please take a look at this and respond. Thanks. From: Alfonso Arana Date: Friday, April 17, 2020 5:53 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6J (b) (6J>;Robert .Thompson@crlcorp.com (b) (4) Dr. Fauci, good morning thank you for all you do for this great nat ion! We are very blessed to have you at the forefront of this pandemic. Not sure if you recall, (b) (6J we have (b) (4) Alfonso Arana President/ CEO Craft Artisan Design Inc. HUBZone DBA. BizSecure https://bizsecure.us (b)(6) CONFIDENTIALITY NOTICE: This e-m ail message including attachments, if any, is in tended only for the person or ent ity to which it is addressed and may contain confidential and /or privileged material. Any review, use, disclosure or distribution of such confidenti al inform ation without the written authori zation of Craft Artisan Design Inc. DBA A&A Solutions. is prohibited. If you are not the int ended recipient, please contact t he sender by reply e-mai l and destroy all copies of the original message, by receiving this e-m ail you acknowledge that any breach by you and/or your repr esentatives of th e above provisio ns may entit le A&A Solutions., to seek for damages. From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Fri, 17 Apr 2020 02:48:07 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [El FW: Hilary Marston's COVID-19 talk now archived for view ing Greg: Please see me tomorrow abo ut some ideas that l have about COBfD-19 slides. Thanks, Tony -----Original Message ----From: Rob erts, Jacqueline (NIH/OD) (E] Date: Thursday, April 16, 2020 3:12 PM (b)( To: NIH-STAFF@LJST.NIH.GOV Subject: Hilary Marston's COVJD-19 talk now archived for viewing Dear Colleagues, Thank you all for your suppo rt as we launc h the new COV[D-19 lecture series. The live videocast of yeste rday's talk was in high demand and, unfor tunately, many of you were unable to gain access. This was partly because of the large number of viewers. We are working to remedy the issues in preparation for next week's lecture. Dr. Marston's talk , "The Biomedical Research Response to COVID-19: A View from NIAID," is now archived at https://videocast.ni h.gov/watcb=36375 . - The COVID-19 SIG Moderators For more infonnation about the COVTD-19 Scientific Interest Group, refer to httos://oir.nih.gov /s igs/cov id-19sci entifi c-i ntere st-gro up. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 17 Apr 2020 02:45:01 +0000 Collins, Francis (NIH/OD) [El RE:conspiracy gains momentum Francis: (b) (5) Best, Tony -------- From: Collins, Francis (NIH/OD) [El Date: Thursday, April 16, 2020 5:02 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(6) :;.=======~~ (b)(6) _______ Cc: Tabak, Lawrence {NIH/OD) [E] (b)( ; Burklow, John (NIH/OD) [E] ._ Subject: conspiracy gains momentum --------- (b)(6JJ; Lane, Cliff {NIH/NIAID) [E] (b)(6) _. (b) (5) https :// www.mediaite.com/tv started-in-wuha n-lab/ /foxs-bret-ba ier-so urces-i ncreasingly-confident-coronavi rus-o utb rea k- (b) (5) Francis From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 17 Apr 2020 02:28:05 +0000 To: Pottinger, Matthew F. EOP/WHO;Birx, Deborah L. EOP/NSC Cc: Subject: (b)(6) RE: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL) Using grounded aircraf t to treat COVID patients Matt: (b) (5) ----- (b)(5). Let us discuss further. Best regards, Tony From: Pottinger, Matthew F. EOP/WHO Date: Thursday, April 16, 2020 7:54 PM To: Birx, Deborah L. EOP/NSC -------- ---------- (b)(6) =(b=)(=6)>; Fauci, Anthony {NIH/NIAID) [E) (b)(6) Subject: FW: (WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Deb, Tony, (b) (5) Best, Matt From: Skinner, James B. EOP/NSC (b)(6) Date: Thursday, April 16, 2020 6:53 PM To: Pottinger, Matthew F. EOP/WHO -------~~ (b)(6)> Cc: DL NSC NSA FO Staff Subject: FW: [WARNING: UNSCANNAB LE EXTRACTION FAILED)[EXTERNAL] Using grounded aircraft to treat COVID patients Matt, I spoke to Leland earlier this afternoon and he asked I pass this along to you . James From: Leland Schwartz Date: Thursday, April 16, 2020 6:08 PM ----------- (b) ( > To: Skinner, James B. EOP/NSC (bH > ___ .;.__--=======~;-:--:-:-::-:-::-:--:-:-:-:-~ _c_ c:_R_a..:.. Ip_h_C_ra_ft_s!:=======--=::"'";" (b_H_. ; BARBARASCHEIDE (b)(6) ----- (b) C6l; Ed Betts Subject: [WARNING: UNSCANNABLE EXTRACTION FAILED][EXTERNAL] Using grounded aircraft to treat COVIDpatients Matt, Oxygen therapy scientists can treat patients using the grounded airliners all over the country as masstreatment chambers. Please watch this explana t ion from Extivita in Durham : > https:// www.youtube.com/watch?v=SWCHDuUOHSM&featur e=youtu. be< Pleasehelp us connect to the right people. This could help save lives, get our economy restarted, and ensure continuity in the government. Hope you're good. Catch up on the other side. Have figured out how to save local news. Leland (b)(6) James, Thanks very much for your help. Leland lelllndSchwartz Edllor&Pui>hsher F~ ChannelOne $4042.213r6 eclllOff!lauqu,oichannoloorn wwwfctUqUDR:himnel CQfn COY.M~ ITY eAOO.DCASTING FORFAUOUIEA April 16, 2020 Matt Pott inger Deputy National Security Advisor The Whit e House 1650 Pennsylvania Avenue, NW Washin gton , DC 20502 Dear Sir, Many of us in the hyperbaric medicine community believe that there exists a simple therapy to halt the inflammatory proc ess and reverse the lung damage. This process will also simultaneously provide many time s over the amount of oxygenation offered by th e coma-inducing intubation ventilator procedure. We are reaching out to our network to make contact with the airlines to secure the use of an airplane with an onboard APU (Auxiliary Power Unit--used to pressuriz e the aircraft) for a month, to treat COVID-19 pati ents and show the effectiveness of th e concept. Initial testin g indicat es in one trial study 100% improvement while all others und erway, although small scale, are showing great benefit at extremely low cost and patient risk. So what is this new procedure? Hyperbaric Oxygen Therapy or HBOT; first used successfully in 1918 for Spanish Flu cases. HBOT is viable and appears to work well but we do not have th e number of pressure vessels / HB chambers available to treat the possibly 100,000+ who need the therap y now. Several of us in our small community have arrived at the same idea in several countrie s. The idea is no longer new or uniqu e. Again, I am proposing use an aircraft as the pressure vessel. Every airplane with a pressurized cabin (i.e., all commercial airline aircraft) is routinely pressurized to around 9 psi (some go higher) while they are on the ground, as part of their norma l airworthiness testing. Myself and others have suggested that one or mor e of th e hundr eds of grounded aircraft be provided to complete th e trial test . 737 Max are not flying but are a perfect pressure vessel for the proc edur e. Could you help us contact Boeing, the airlines or the military? No aircraft modification is required whatsoe ver so that is one of the issues off the table. The aircraft remains parked on the ground with access for ambulatory patients via a stairway. No jetway is required unless we expand this in the future for non-ambulatory patien ts. We would need to place stand ard DOT portabl e oxygen tank s in the cabin along with the associated manifold, pressure regulator, flow-meters and tubing. Each patient will have his / her own anesthesia mask and breathing circuit. Ther e is no cross contamination between patients or the cabin environment atmosphere as each mask incorporates a Viral Filter Kit to help protect the technicians who are also brea thing from a sec ur e, clean so urc e. All safety issues are addressed in the plan. The same process, once proven could be utilized by our military and of course our Navy who is experiencing possible outbreaks as we speak The Patriot Clinic in Oklahoma City is my personal charity where we have provided over 15,000 free HBOT treatments for our beloved vets and 30,000+ at cost or below. We are not asking for money. Nor, am I selling anything in this effort. With th e help of a small group of supporters, ( Ralph Crafts & family ) my company is willing to provide the equipment, training and technical support to begin the process. Thank you for your ongoing service to our country, and thank you for reading and considering my propo sal. I sure would appreciate your help. Semper Fi! Sincerely, Edward A Betts Edward A Betts ANDI American Nitrox Divers International 74 Woodcleft Avenue Free ort, NY USA 11520 (b)(6) >http: //www .andihq.com/ < (b)(6) Matt Pottinger Deputy National Security Advisor The ·white House 1650 Pennsylvania Ave., NW Washington , DC 20502 Sir: As one old Marine to another Ma rine, this letter contains the "straight scoop," and is intended to provide infonnation that can help stop the spread of COVID-19, and ensure the continuity of critical segments of government. Hyperbaric Oxygen Therapy (HBOT) has been in use for over 100 years, and was the only effective treatment for the 1918 flu pandemic. HBOT is being used worldwide to treat a variety of serious disease s, and has been proven to be immediately effective in treating seve re COVID19 cases, with a success rate close to 100%. HBOT is simply breathing high-pur ity oxygen (92% or higher) for 60-90 minutes in a pressurized environment (typically between 8 and 15psi- the higher pressure is about the same pressure as doing a SCUBA dive to 33 feet). HBOT chambers can be 1-2 person sizes and portable, up to 12-seat chambe rs which are used for Navy operations. (b)(6) I have a oneperson chamber in our home , and we can attest to its effectiveness in treating severe breathing problems, like pneumonia , infections , and wounds. The currently publicized and widely accepted statement that there is no effective treatment for COVID-19 is wrong. HBO T treatments, usually just a single one-hour session, provide immediate improvements in lung function, blood-oxygen levels, and organ recovery . Unlike respirators, which do more damage than good and are basically a death sentence, HBO T provides an immediate path for recovery and healing. A team of ve1y experienced scientists and HBOT experts have developed a concept that will enable the effective treatment of large numbers of people by using some of the thousands of grounded commercial aircraft as large HBOT chambers. I'm an old Marine Corps jet pilot , and we use our (b) (6) so I have the professional contacts to confirm and verify the efficacy of the concept. Every airp lane with a pressurized cabin (i.e., all airline aircraft) is routinely pressurized to around 9psi (some go higher) while they are on the ground , as part of their normal airworthiness testing. We have equipment staged and ready to go now, to treat 25 COVID-19 patients ata time- we need an airplane, and we can be treating people and saving lives in about 36 hours. The aircraft we need remain park ed on the ground, no modifications are needed-we will simply place portable oxygen tanks in the cabin with the associated tubing , manifold, and pressure regulators, and each patient will have his/her own anesthesia mask. There is no cross contamina tion between patients, because everyone is breathing oxygen from their own persona l mask. We are reaching out to our contacts in the airlines to ask for the use of an airplane and APU (Auxiliary Power Unit- used to pressurize the aircraft) for a month, to treat COVID- 19 patients and show the effectiveness of the concept. We could do the same thing with a single military transport aircraft (many of which have been configured for medical use). As a Marine, and with my knowledge of HBOT, the recent death of the Theodore Roosevelt sailor is part icularly upsetting, knowing that a couple of Senior Chiefs or Marine Master Sergeants could have configured an aircraft in Guam in a couple of hours and be treating all the sailors from the carrier. We are not asking for money- my wife and I are paying for all the required equipment and support personnel. HBOT chambers are easily implemented and supported- you could have one in your office (ours is 8' long and 34" in diameter when pressurized) and it would only take a couple of hours to train your corpsmen to operate it. I don' t know of a better guarantee of continu ity in the current pandemic. Please note that (b)(6) I have no financial or political interests in the HBOT treatment concept, companies , or manufacturers-we receive no benefits/rewards, other than helping to save many lives. You will receive a letter from Ed Betts- he's a good man, really knows his stuff, and I trust him with my life- please take what he says seriously. Thank you for your ongo ing service to our country , and thank you for reading and consid ering the information in th is letter. Semper Fi ! Respectf ully, Ralph E. Crafts Marsha ll, Virg inia (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 12:37:38 +0000 Dr. Josh Backon RE:Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) To: Subject: You are not being ignored. The Nationa l Heart Lung and Blood Institute will take a look at this. From: Dr. Josh Backon Date: Thursday, April 16, 2020 8:09 AM To: Coleman, Amanda {N IH/NIAID) [CJ ____ ..:._ __ _:__:. __ -------- :...,:_.:.!:::========:::....:..-~ ""=""'"'= (b)( >; Fauci, Anthony (b ~)~(6) (NIH/NIA ID) [E) Subject: Fwd: Covid-19. thromboxane inhibitors, and heme binding (02 desaturation) Continue to ignore me. http ://www .htct.com .br/en -hemog lobin -va lue-may -be-decreas ed-avance S2531137920300298?fbclid= lwAR3zdsUZE l MSgxNpqzr lf8621NlbRMFPJ9qfRLnsC2FqZNkjCrsw4KDtGc Dr. Josh Backon backon@mail.huj i.ac.il ---------- Forwarded message --------From: Coleman, Amanda (NIH/ NIAI D) [C] (b)(6) Date: Thu, Apr 9, 2020 at 6:18 PM Subject: RE: Covid-19. thromboxane inhib itors, and heme binding (02 desaturation) To: Dr. Josh Backon Dear Dr. Backon, We very much appreciate the information you've provided, and I am sharing your updates with t he relevant staff at NIH. We have directed you to the information we think is relevant for your request, and we hope that this has been helpful. We have no additional information to provide at this time. NIAID staff members will not be responding further . Thank you, Amanda Coleman, MPH [C) Office of Scientific Coordination and Program Operations Division of Microbiology and Infectious Diseases NIAID, NIH, DHHS From: Dr. Josh Backon Date: W ednesday, April 8, 2020 7:37 AM ------~~ To: Coleman, Amanda (NIH/NIAID) [CJ CbH6)>; Fauci, Anthony (NIH/NIA ID) [E) (b)(6) Subject: Covid-19. thromboxane inhi bi tors, and heme binding (02 desaturation) I have a suggestion for 3 potent antiviral agents, cheap and readily available, that may prevent viral shedd ing. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. Two of the items also positively affect heme binding. Covid-19 bind s to heme causing 02 desaturation, lung failure and death. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publications quoted by over 750 other researchers www.google.com /scholar?start=O&g=%22backon ++j.%22&hl=en&as sdt=0,5 and in over 250-300 texts as per https://www.google.com /search?tbo=p&tbm =bks&q =%22backon+j .+%22&num = 100 ). In the 1980's he was Consulting Editor of the Journal of Pedi atric Endocrinology, Editor of Reviews in Pure and Applied Pharmacological Sciences, and Associate Editor of the International Journal of Adolescent Medicine and Health. From 19902004, he was a consultant on emergency planning and management at Israel 's National Police Headquarters with Nitzav Mishneh Dann y Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid- 19. Its mechanism was found in the 1970's to inhibit thromboxane https://scholar .google.com/scholar?hl=en&as sdt=0%2C5&q=chloroquine +thromb oxane&btnG = The problem with chloroquine was that it also elevated levels of prostaglandin F2alpha. In 1980, Srivastava, an Indian biochemist working in Denmark found that GINGER is a potent inhibitor of thromboxane synthetase. I wrote a number of pap ers in the J980's on use of ginger: https:/ /scholar .google.com/scholar ?hl=en&as sdt=0%2C5&g =backon +ginge r&btnG= CHLOROQUINE FOR TREATING COVID-19 bttps://scbolar.google.com/scholar ?hl=en&as sdt=0%2C5&q=ch1oroquine+covid19&oq=c h&fbclid=IwAR llLe376M22 IUr3U sD6 yzsASmpGglp I3h3PTOpC HA4Y cu32 l ZPevD-A GINGER IS A POTENT ANTIVIRAL - https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =ginger +anti viral&oq =gm THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) https: //scholar .google.com/scholar?hl =en&as sdt=0%2C5&q =turmeric+antiviral& oq=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting, N Dong , L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 - ACS Publications .. . These results offer theoretical support for the development of CCM-CDs as a hopeful antivira l drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INIDBIT INFLAMMATORY CYTOKINES {iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS Mortality in COVID-19 patients is usually from ARDS (acute respiratory distress syndrome) via inflammatory cytokines. Apart from N-acetylcy steine which was found 3 years ago to elevate atrial natriur etic factor [found by Kiemer in 2001 to zap inflammatory cytokine s: iNOS , NF KappaB , and TNFalpha) now piperine in black pepper was found to inhibit inflammatory cytokines [piperine also dramatically increas es oral bioavailability of turm eric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE https://scholar.google .com/scholar ?hl=en&as sdt=0%2C5&g=nacetylcysteine+%22 inflammatory+cytokines%22&btnG= PIPERINE https://sc holar .google.com/ scholar ?hl=en&as sdt=0,5&q =piperine%20inflammato ry%20cytokine s&btnG=&fbclid=IwAR0kXZxl66JPLFPry2MDTDxOAelgGnmB ZdK.Bw7cl v78Hfi7t 0JJnx0Y2zuE COVID -19 BINDS TO HEME http://web.archive.org/web/20200405061401/https://medium.com/@agaiziunas/covid-19-had-us-allfooled-but-now-we-might-have-finally-found-its-secret-91182386efcb COVID- 19: HYPOXIA , 02 DESATURATIO N, COVID-19 BINDS TO HEME. THUS NO MAX PEEP ! ! IT'S A PROBLEM OF FREE RADICAL BIOCH EMISTRY. THROMBOXANE AND HEME BINDING https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=thromboxane+%27heme+binding%22&oq =th&fbclid= lwAR3fSECaUUnrSSyhCA6kpJ9z0nPaMM3ba7HtuFPpQ9B1PVrF9kdwayATcY0 INDIA: POPULATION 1,300,000,000: as of Apr il 8th , only 5000 cases and 164 deaths : [Ind ians eat GINGER,TURMERICand BLACKPEPPERplus other spices which are thromboxane inhibitors ]: https ://www. business-standard .com/ article/ current-affairs/ coro navi rus-I ive-u pdates -covid-19-cases -i ni ndia-gl oba I-death-to II-state -wi se-del hi-ma harasth ra-tabl igh i-niza m udd i n-lockdown-extension-latestnews-120 040800236 1.html 11 classic Ind ian spices: saffron , fenugreek, cardamom , cloves, cassia, cumin, coriander, and nutmg https ://www .thekitchn.com/11-essential-spices-for -indian-cooking-223152 Access http://scholar.google.com for THROMBOXANE (and the name of each spice) and you'll see that each one is a thromboxane inh ibitor ANTI PARASITICDRUG IVERMECTIN KILLSCOVID- 19 https://pharmafield.co.uk/pharma news/study shows antiparasitic drug ivermectin kills coronavirus/ IVERMECTINAFFECTSTHROMBOXANE https://scholar.google.com/scholar?hl=en&as sdt=0%2CS&q=%22ivermectin%22+thromboxane+&btnG CARBON DIOXIDE AS THROMBOXANE INHIBITORS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433448/ https://www.sciencedirect .com/science/article/abs/pii/0306987786900952 Effect of carbon dioxide on platelet aggregation in cats ES Gabrielyan , EA Amroyan - Bulletin of Experimental Biology and ... , 1984 - Spri nger Products of the arachidonic acid cascade have been shown to play an important role in regulation of the blood supply to several organs, including the bra in [i, 8]. Cyclic derivatives of arachidonic acid play a definite role in the mechanisms of action of many known ... https ://Ii nk.springer .com/ article/10.1007 /BF0082963 7 WHY CATS (FELINES)ARE MORE SUSCEPTIBLE TO COVID-19 THAN DOGS https ://www. the -scientist. com/news -op inion/ cats-f e rrets -susce pt i b Ie-to -sars-cov-2 -st udy67374? utm campaign=TS DAILY+NEWSLETTER2020&utm source=hs email&utm med ium=emai l&ut m content=85706789& hsenc=p2ANqtz --SZXoVVbO1SHcR025FPiWgMcM3 nz7fHSHOrKRp9fLxTy9Bxj0Jsl7hJtDQ oDM2xsozsH438n5c 1Mj78bT3Rz2mQ& hsmi=85706789&fbclid=lwAR3bW76GVl4rConuw7YPcDL91ZE9JkQQSm9Lu yRE4y2LNmo0o6v taFUk https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476 5381.1983.tb09393.x?fbclid=lwAR1SzFkyOR4mVyVvh9ayQP zj4Cwl Vo419b2jRHebfjmSQCD6BykteHqQ U- From: Fauci, Anthony (NIH/N IA ID) [E) Thu, 16 Apr 2020 11:48:56 +0000 Date: To: (b)(6) Subject: RE: Stand ing Up for Truth David: Ma ny hanks for your kind note. It is much appr eciat ed. Best regards, Tony (b)( 6) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)( 6) FAX : (301 496- 09 E-mail Cb)(6) The Information in this e-mail and any of Its attachments Is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representative s . ------------------------:a- From: Date: Monday , Ap ril 13, 2020 2:49 AM To: Fauci, Anthony (NIH/ NIAID) [E] (b)( 6) -------- (b)(6) = (b)(6); Fauci, Ant hony {NI H/ NIAID) [E] Subject: Standing Up for Truth 4/ 13/20 Anthony S. Fauci, M.D. Director , NIAID Dear Dr. Fauci: As a fellow graduate of Regis High Schoo l (b)(6) and very active alumnu s, I am writing to you out of deep concern for our nation . I am reading reports in The NY Times that President Trump may be con sidering firing you for tell ing the truth about the negative consequences of delays in mobilizing the Amer ican res ponse to the corona virus threat. The Times had run article s in recent days detail ing the pertinent facts that place the blame for this delay squarely on President Trump. We can reasonably infer that significant loss of life and financial harm resulted from this delay. The mission of Regis was to mold young men with leadersh ip potential to be "men for others" in the Jesuit tradition. To achieve that goal Regis also sought to hone our intellectual talents and imbue us with Christian morality to succeed throughout our lives in a persistent pursuit of excellence, which embodies the truth. A mission to relentlessly pursue and proclaim the truth. The fact that you have cons istently and courageously pursued that mission during one of the darkest times in our history explains the extraordinary admiration in which you are held by millions of Americans. You have won their confidence , which has enabled so many to make exquisite sacrifices to win this crucial battle. People will follow heroes, which is precisely how the vast majority views you. I am writing because I want you to know how important you are to America. We cannot lose you and we can not lose the value of truth. Truth must prevail or our precious democracy is in grave peril. Consequently, and I know I speak for the vast majority of Americans whose decency is beyond question, if Donald Trump seeks your removal, please resist for the sake of our nation. An appeal to the populace will not go unanswered. Religious leaders will flock to your defense, as will the media and leading political leaders, including Biden and Cuomo. Republicans can not afford to alienate what you stand for. Jeopardizing the Catholic vote would be suicide. In closing, know how proud all Regians are of you. You will always be an inspiration to those who understand the value of service to others. Our prayers are with you. David G. O'Brien Attorney at Law (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:35 :55 +0000 Daniel Bednar ik Lerner, And rea (NIH/NIAID) [El RE: BARDA Presentation To: Cc: Subjec t : Thanks, Dan. Best, Tony From: Daniel Bednarik Se nt : Tuesday, April 14, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6)> Subject: BARDA Presentation ------~~ Dear Tony : (b) (4) Be well - we are all in your corne r (and you have your own bobble head likeness)! Best, Dan Daniel Bednarik, Ph.D. Senior Vice President Molecular Engineering Nexlmmune, Inc. 9119 Gaither Road Gaithe rsburg MD 20877 (b)(6)(m) www.neximmune.com •• • Nexlmmune Directing T cell function to restore natural immunity From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:33 :57 +0000 To: Schwetz, Tara (NIH/OD) [E) Cc: Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C];Walsh, Elizabeth (NIH/OD) [E] Subject: RE: Flagging NIH Media Products Thanks, Tara . I appreciate the heads up. Stay well and saf e. Best, Tony From: Schwetz, Tara (NIH/OD) [E) (b)(6)/> Date: Tuesday, April 14, 2020 4:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b -=-= )'""' (6) => Cc: Marston , Hilary (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID ) [E] (b)( >; Barasch, Kimberly (NIH/N IAID) [C] (b)( >; Walsh , Elizabeth (NIH/OD) [E] (b)( > Subject: Flagging NIH Media Products Tony, Hope all is we ll and that you are staying safe and healt hy . . Our plan is to batch and send these to Hilary, Patty, and Kim on Thursdays/Fridays each week, unless there is a time sensitivity to them. For t he time-sensitive requests, I will flag them for you (after a couple levels of filtering). So, that said, I am reaching out to flag the following time-sensitive items for your awareness and sharing with the remainder of the Task Force, as appropriate . You'll note that both of these are yours, so th is email may be unnecessary. If so, apologies for adding to your (what much be crazy) inbox. Item 1: National Institute of Allergy and Infectious DiseasesStrategic Plan for COVID-19 Research (NEW) Activity Type: Strategic Plan Summary: A new strategic research plan from the National Institutes of Health aims to build on - and accelerate - new and existing research efforts to prevent, diagnose, and treat COVID-19, as well as understand the underlying causative agent of this disease, severe acute respi ratory syndrome coronavirus 2 (SARS-CoV -2). The Plan prioritizes research to improve fundamental knowledge of SARS-CoV-2vir us and COVID-19 disease, develop diagnostics and assays, characterize and test t herapeutics, as well as develop safe and effective vaccines targeted to ward decreasing disease incidence, mitigating morbidity, and preventio n mortality from this disease. Impact on COVID-19 Pandem ic Response: The strategic plan outlines a research plan ta rgeted at prevent ion and mitigation of COVID-19disease. Office : NIAID, Office of the Director NIH Point-of-Contact : Anthony Fauci, M .D. NIH Point-of-Contact Email: Action Date: Estimated 4/17 /2020 _ Type of Action : Publication (b)(6) Potent ial for Press Coverage : Mainstream Press Press Release in Development? :Yes Item 2: NIH study validates decontamination methods fo r re-use of N95 respirators Activity Type : Significant scientific finding Summary ; NIAID/NIH-funded study shows that N95 respirators can be decontaminated effec tively and maintain funct io nal integrity fo r up to three uses. Researchers tested the decontamination of small sections of N95 fi lter fabric that had been exposed to SARS-CoV-2. Decontamination methods tested included vapor ized hydrogen peroxide {VHP), 70-degree Celsius dry heat, ultraviolet light, and 70'/o ethanol spray . All four methods eliminated detectable viable virus from the N95 fabric test samples. The results will be posted on a preprint server (timing TBD). The findings are not yet peer-reviewed but are being shared to assist the public health response to COVID-19. Impact on COVID-19 Pandem ic Response: Study shows that respirators could be used multip le times {2-3 times depend ing on decontamination method) ICO: NIAID NIH Point -of- Contact : Vincent Munster, Ph.D., and Marshall Bloom, M.D., from NIAID's Laboratory of Virology are available to comment on this study . POC Email: ------------------- Action Date: TBD week of Apr il 13, 2020 Type of Action: Report/Publication Potential for Press Coverage: Mainstream Press Press Release in Development? : Yes Hope you're getting some rest and taking care of yourself! Best, (b)(6) Tara A. Schwetz,PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: --- ~= (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 11:32:27 +0000 To: Subject: (b)(6) FW: New web porta l ··· UW IDEA: COVID-19 Treatment https://bit. ly/3ckkv48 Please take a look at this and then let us talk. From: Folkers, Greg {NIH/NIAID) (E] (b)(6) Date: Tuesday, April 14, 2020 5:19 PM Subject: New web portal --- UW IDEA: COVID-19 Treatment https://bit.ly/3ckkv48 Disclaimer : Any third-party material in this email bas been shared for internal use under fair use pro visions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NlH , HHS, or the U.S. government. From: Date: To: Cc: Subject: Attachments: Proposals 4.14.pdf Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 11:24 :00 +0000 Auchincloss, Hugh (NIH/NIAID) [C) (b)(6) Conrad, Patricia (NIH/NIAID) [E);Harper , Jill (NIH/NIAID) [E] FW: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 2020-04-14_ Proposal POCSign up.xlsx, IC Specific Proposals 4.14.pdf, ER Please handle. From: Schwetz, Tara {NIH/OD) [E] (b)(6) Date: Tuesday, April 14, 2020 8:52 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L ; NIH Director's Executive Committee <0D SmallStaff@mail.nih .gov> Subject: Request: Proposal Summaries- POCsDue 4/15; Summaries Due 4/20 Colleagues, As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man (b)(6) by S pm on W ednesday April 15. We will t hen col late and distribute the comp Iet ed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them . ----------- We ask tha t, once t he POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate t he IC proposals as much as possible; however, it is fine (for valid/justifiable reasons) to describe a few unique projects tha t fall under the theme as well. That is, if they don't make sense to integrate , you don' t have to, but please be sure to include t hem in the summary . These summaries should be sent t o Larry and me (cc Jordan Gladman) by noonon April 20. We wil l build off these summaries t o generate a document for Francis' review, which we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short: • Ap ril 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm -chairs to send a 2 page summary of their theme (with combined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~= P: (b)(6) I M: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 02:51:30 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Emergency clinica l tr ial COVID PE 4_ OVID_protocol_15042020.docx To: Subject: Attachments : Pleasetake a look at this and take care of it. Thanks. From: Kucher Nils (b)(6)> Date: Wednesday, April 15, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E] ______ (b ""~""'(6) => Subject: Emergency clinical trial COVID PE Dear Anthony My background is clinical VTE research. I spent many years in Boston (Harvard Medical School). We may have a solution for improving survival in COVID outpatients. (b) (4), (b) (5) Would you be willing to discuss this urgent clinical trial proposal wh ich was submitted today to Swiss authorities My mobile is -------- (b)(6) You can call me anytime. Best regards Nils Prof. Dr. med. Nils Kucher Director of Vacular Medicine Univers ity Hospit al Zurich Switzerland Ramistrasse 100, RAE C 13 CH-8091 Zurich Tel: Cb)C6) www.angiologie.usz.c h U Sz Universitats Sp ital Zurich From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:50:34 +0000 DuBois, Raymond N. RE: Mask wearing policy at our University Hospital Ray: Thank you for your note. I would keep the policy "voluntary" but I would "encourage" employees to wear them. Best regards, Tony ---------------=-:-:= --------- (b)(6) From: DuBois, Raymond N. Date: Wednesday, April 15, 2020 7:18 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Mask wear ing policy at our University Hospital > Dear Dr. Fauci, My name is Ray DuBois and in addition to being the Dean of Medicine here at the Medical University of South Carolina in Charleston, I chair the Board of Scientific Councilors for the NCI. The mask wearing policy fo r our Health System is developed by our inf ect ion control group and not by the College of Medicine. Currently, we have a "voluntary" mask wearing policy for the health system and our main University Hospital. Based on your recent comments about asymptomatic and pre-symptomatic carriers of COVID19, do you agree that keep ing this voluntary is the correct approach? Obviously, your opinion here is extremely well respected and I would like for us to prov ide the safest environment possible for our faculty, employees and patients. Ray DuBois, M.D., Ph.D. Dean of Medicine The Me dical University of South Carolina ....Charlesto n, SC Memb er of the National Academy of Medicine From: Date: To: Subject: Stefano: Congratulations! valuable. Fauci, Anthony (NIH/N IAID) [E) Thu, 16 Apr 2020 02:35:18 +0000 Bertuzzi, Stefano RE:Announcement--ASM 's COVID-19 Research Registr y Excellent idea and much needed. Our community will find it very Best regards, Tony From: Bertuzzi, Stefano Date: Wednesday, April 15, 2020 10 :21 AM -------'="'""' = ~--~~======-::__= To: Fauci, Anthony (NIH/NIAID) [E] (b)( >; Erbelding, Emily (NIH/NIAID) [E] (b)(6) >; Cassetti , Cristina (NIH/NIA ID) [E] (b)( ; Beige!, John (NIH) [E] (b)(6)> Subject: Announ cement --ASM's COVID-19 Research Registry Dear Tony and NIAID friends the miss ion of the American Society for Microbiology (ASM) to promote and advance the microbia l sciences has perhaps never been more clearly in focus than during the current SARS-CoV-2 pandemic. Accelerating basic research is key to ASM's mission - it is where cure and prevention begin. It is impressive how rapidly research on SARS-CoV-2 /COV ID-19 has advanced in just a few weeks , but easily accessing new and relevant research has been a challenge for basic researchers . When ASM's Council on Microbial Sciences held a COVI D-19 summit to ident ify the most significant scientific work on the virus , the coronavirus researc hers and clinical microbiologists raised the need for the scientific commun ity to curate important COVID-19 research . ASM is exc ited to announ ce the launch of the COVID-19 Research Registry , a platform curated and vetted by experts in the field of virology and related discipline s to prov ide imm ediat e acce ss to top COVID-1 9 research . I am proud that Lynn Enquist, Ph.D ., Henry L. Hillman Professor in Molecular Biology , Princeton Unive rsity and fo rmer ASM President , will serve as Chief Curator for this Registry. Dr. Harold Varm us , Lewis Thomas University Professor of Medicine , Weill Cornell Medicine has agreed to join us as Chief Consultant on the project. We are honored to have the following as Assistant Cura tors-in-Chief : • Rozanne M. Sandri-Goldin, Ph.D. , Chancellor's Professor , Microbiology & Molecular Genetics, University of California , Irvine and Editor-in-Chief of ASM's Journal of Virology • Vaughn Cooper , Ph.D ., Professor , Microbiology & Molecular Genet ics , University of Pittsburgh , and current ASM Board member The entire curatorial board is listed on the Registry site . ASM is proud to add this initiative to our ongo ing efforts . Through its capillary network of clin ical microbiologists around the country and the world, ASM has accelerated communica tion and cleared roadblocks to ramp up SARS-CoV-2 testing . We continue to work closely with our dedicated colleagues , the indefatigable clinical microbiologists manning the front lines in hospitals and testing labs during this unprecede nted global emergency. We send our thanks - and admirat ion--to these ASM members who are contr ibuting directly to saving lives in this perilous time. Our COVID-19 resource page provides important ASM updates and current inform ation on the coronavirus. We are also working with the news media to provide authoritative ASM experts and reliable material on the microb iology of viral epidemics. ASM journals is also providing free access to more than 50 research articles published over the last year in our 16 scho larly journals and expediting review for submitted papers related to coronavirus, ensuring that new research is quickly made available to the scientific community . We are hoping that researchers will find the COV ID-19 Research Registry a useful resource . We look forward to your comments , questions or suggestions , since your input will be critical for improving this platform and making it usef ul for the scientific community. All feedback can be sent to covid 19reqistry@asmusa.org . We are all in this together. Since rely , Stefano Bertuzzi Chief Executive Officer, ASM Stefano Bertuzzi, Ph.D., M.P.H. Chief Executive Office r Ame rican Society for Microbio logy (ASM) 1752 N St., NW Washington, Phone DC 20036 -2904 (b) (6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 02:08:26 +0000 To: Auchincloss, Hugh (NIH/NIAID) [C) (b)(6)) Cc: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Request: Proposal Summaries - POCsDue 4/ 15; Summaries Due 4/20 Attachments : 2020-04-14_ Proposal POCSign up v l. 0[1] .xlsx, IC Specific Proposals 4.15[1].pdf, ERProposals 4.15[1] .pdf, COVID-19 Initiative Managemen t-revised[l][G] .docx ---------- Please take a look at this and handle. Thanks . From: Schwetz, Tara {NIH/OD) [E] CbH > Date: Wednesday, April 15, 2020 8:59 PM To: ICDDIR-L@list. nih.gov Cc: List DEPDIR-L; NIH Director's Executive Committee <0D Smal1Staff@mail.nih.gov>; Gladman, Jordan (NIH/OD) [El (b)(6J> Subject: Re: Request: Proposal Summaries - POCsDue 4/15; Summar ies Due 4/20 All, Please find attached the comp iled sign-up sheet with IC POCsfor the 12 themes, as well as updated packets to matc h the shifts that were brought to our attention (attachments #1-3) . As a reminder , please send the 2 page summar ies for each theme (with comb ined budget), using the attached template (attachment #4), to Jordan Gladman by April 20 at 12 pm. Thanks to you and your staff for developing these! Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 ---~~ (b)(6) P: (b)(6) I M: From: Tara Schwetz CbH6J> Date: Tuesd ay, April 14, 2020 at 9:01 PM To: " ICDDIR-L@list.nih.gov " Cc: List DEPDIR-L , NIH Director's Executive Committee Smal1Staff@mail.nih.gov > Subject: Request: Proposal Summaries - POCsDue 4/15; Summaries Due 4/20 Colleagues, <0D- As discussed this afternoon, please find attached the POCsign-up sheet (tab 1; tabs 2-3 list the various proposals by category, theme, and IC), the IC-specific proposals, and t he economic recovery proposals . We ask that you please complete the POCsign-up and send it to Jordan Glad man {jordan .gladman@nih .gov) by 5 pm on Wednesday April 15. We will t hen col late and distribute the completed spreadsheet to the Chairs for each of the themes and post it on the ICD SharePoint site . The individual proposals are imbedded in the pdf as folders sorted by theme. If you fee l your proposal would fit better w ith a different working group, please feel free to engage with them. We ask tha t, once the POCshave been have been ident ified, you quickly assemble to begin refining and synergizing your proposa ls. Each Chair should coordinate with their group to develop a 2 page max summary of the theme's research, along with a single combined budget. The summary should integrate the IC proposals as much as possible; however, it is f ine (for valid/justifiable reasons) to describe a few unique projects that fall under th e theme as well. That is, if they don't make sense to int egrate , you don't have to, but please be sure to include them in the summary. These summaries should be sent to Larry and me (cc Jordan GIadman) by noon on April 20 . We wil l build off these summaries t o generate a document for Francis' review, whic h we ultimately hope will be informative as we prepare for a potentia l fourth supplement. The ask in short : • April 15 at 5 pm - send your POCsto Jordan, who will then distribute the completed spreadsheet to the chairs • April 20 at 12 pm - chairs to send a 2 page summary of their theme (with comb ined budget) Best, Tara A. Schwetz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: ----=-:,~ (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 16 Apr 2020 01:58:31 +0000 To: My les, Renate (N IH/OD) [E) Cc: Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wolinetz, Carrie (NIH/OD) [El;Bur klow, John (NIH/O D) [El;Fine, Amanda (NIH/OD) [El;Lane, Cliff (NIH/NIA ID) [E];Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: FOR YOUR REVIEW: Draft ACTIV News Release Attachments : OD_ACTIV_PPP_Release_4.15.2020 - with m inor trac ked edits.docx Looks good. See my very minor t racked edits in attached document. Than ks, Tony ------- From: Myles, Renate (NIH/OD) [El Date: Wednesday, Apr il 15, 2020 9:50 PM (b)( > ------~~ To: Fauci, Anthony {NIH/NIAID) [El (b)(6)> Cc: Collins, Francis (NIH/OD) (El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6) Wol inetz, Carrie (NIH/OD) [El (b)(6)•>; Burklow, John '":":"".".".""."':":-:-:-:-:-::-=====--=-=-:-= (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)( >; Lane, Cliff ~======="'=r:.. (b)(6Ji; Billet, Courtney (NIH/NIAID) (E] (NIH/NIAID) [El (b)(6J>; Stover, CbH >; Routh, Jennifer (NIH/NIAID) [El Kathy (NIH/NIAID) [El (b) (6) > Subject: FOR YOUR REVIEW: Draft ACTIV News Release Hi Dr. Fauci: Dr. Collins asked that I send the draft ACTIV release for you review. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communications and Public Liaison National Institutes of Health Tel: (b)(6) Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:26:51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Cc: Greg Folkers (bH ;Billet, Courtney (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID ) [CJ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Attachments: Fauci 2020 AIRI Public Service Awar d Letter .pdf From: Date: Patty: Please put together (or have Kim do so) a letter of thanks, honor, and appreciation ...yada yada . So that they know I have received the lette r and look forward to receiving it at an appropriate tim e. Th anks, Tony From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, April 15, 2020 4:54 PM To: Fauci, Anthony (NIH/NIAID) [El------~= Cc: Tabak, Lawrence (NIH/OD) [El~======-~ Subject: FW: AIRI Presents Dr. Fauci with 2020 Public Service Award Cong rats, Tony! Please try to take a minute to savor this. Or at lea st 15 seconds. Q Francis From: Parker, Nicole Date: Wednesday, April 15, 2020 4:10 PM -----~~ To: Collins, Francis (NIH/OD) [E] (b)(6)>; Wolinetz, Carrie (NIH/OD) [E] (b)(6) ; Hallett, Adrienne (NIH/OD) [El (b)(6) >; Lauer, Michael "'.": (N -:-: l"."'.' H/-:-:: 0:-:D-:) -:-:: [E ::-; ] ;:::::=====:::;.___., (b a"'<" ~~(6) > 1 Cc: O'Hare, Libby Subject: AIRI Presents Dr. Fauci with 2020 Public Service Award Good Afternoon , On the behalf of the Association of Independent Research Institutes (AIRI), I wa nted to notify you that AIRI has awarded Dr. Tony Fauci with its 2020 Public Service Award in recognition of his exemplary leadership during the novel coronav irus pandemic. The AIRI Public Service Award is the highest honor awar ded by our organ izat ion and we're very pleased to present th is award to Dr. Fauci. A list of past awardees can be fo und here . Please see the official award letter attached and let us know any questions . Regards, Nicole Parker, Ph.D. AIRI Washington Office - lewis-Burke Associates, LLC 440 1st Street NW Suite 700 Washington, DC 20001 202-289-7475 Nicole@lewis-burke.com www.lewis-burke.com Disclaimer: This message is intended only for the named recipient. If you are not the intended recipient you are notified that disclosing, copying , distributing or taking any action in reliance on the contents of this information is strictly prohibited. From: Se nt: To: Subjec t: Attachment s: Fauci, Anthony (NIH/NIAID) [E] Wed, 15 Apr 2020 15:57:38 +0000 Awwad, David (NIH/NIAID} [C] Threat assessment 4/14 Total Fauck Up, Re: Finis Covid Opus, Re: Total Fauck Up, Untitled From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 10:45:28 +0000 Birx, Deborah L. EOP/NSC;Troye, Olivia EOP/NSC RE: Does G6PD Deficiency Relat e to COVID-19 Infection? To: Subject: I Med Page Today The issue also comes up when people are on certain drugs. ----------- From: Birx, Deborah L. EOP/NSC Date: Wed nesday, April 15, 2020 6:16 AM To: Troye, Olivia EOP/NSC --------- (b)(6) (b)( (b)(6)> ; Fauci, Anthony (NIH/NIAID) [E) Subject: Re: Does G6PD Deficiency Relate to COVID-19 Infection? I MedPage Today This one always comes up when we have differential responses to an infection - in HIV there are genetic links to better outcomes. From: "Troye , Nsc" Cb)(6) Date: Tuesday, April 14, 2020 at 11 :03 PM To: "Birx, Deborah L. EOP/NSC " ----------~ (b) (6) > ----------- CbH6J>,"Anth ony Fauci [E]" Subject: Does GGPD Deficiency Relate to COVID-19 Infection? I MedPage Follow up article to some previous emails. Just wanted to send this your way. https://www.medpagetoday.com/infect iousdisease/covi d19/85929 Olivia Troye Special Advisor for Homeland Security and Counterterrorism Office of the Vice President White House Coronavirus Task Force Office: (b) (6) Mobile: (b)(6) (Does not receive texts) ----- --------- Today (bXS) PCP. From: Date: To: Cc: Subject: Attachments : Greg: Nice job. Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 02:32:49 +0000 Folkers, Greg (NIH/NIAID) [E) Billet, Courtney (NIH/NIA ID) [El;Conrad, Patricia (NIH/NIAID) [El RE:ASF - here that proposed op-ed for you and Dr. Birx penned by VP office Birx.Fauci Op-Ed clean - with Fauci tracke d changes.docx I have made a few edits that are tracked into the attached document. Please accept the changes and submit back to them. Thanks, Tony From: Folkers, Greg (NIH/NIAID) (El -------- (b) ( > Date: Monday, April 13, 2020 4:06 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: ASF - here that proposed op-ed for you and Dr. Birx penned by VP office ------~~ --------- 5> Please review if/when u have a chance . CbH ASF- CIea n -----------vers ion and tracked version. From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 7:20 PM To: Folkers, Greg (NIH/NIAID) [El Cc: Billet, Courtney (NIH/NIAID) [El (b)(6) -------------~= -------- (b) ( > > (b)(6J>;Conrad, Patricia (NIH/NIAID) [El (b)( Subject: RE: ASF/ FW: proposed op-ed for you and Dr. Birx? (b) (5) From: Folkers, Greg (NIH/NIAID) [El (b)(6) Date: Wednesday, April 8, 2020 5:13 PM To: Fauci, Anthony (NIH/NIAID) [El 4 CbH 6?i> Subject: ASF / FW: proposed op-ed for you and Dr. Birx ? ------= = From: Billet, Courtney (NIH/NIAID) [El (b)(6J> (b) (5) -----------------~~ --------- From: Miller , Darin B. EOP/OVP Date: Tuesday, April 7, 2020 3:07 PM To: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, April 14, 2020 10:23 Arvl To: Fauci,Anthony (NIH/NIAID) [El------(b =-= )..., (6) => Subject: Washington Post Dear Tony, Is there a national strategy at the task force level to coordinate clinical research efforts nationally? We have heard lots of complaints that there isn't a national strategy. I talked to Cliff Lane about this, but we want to give you the chance to respond. Carolyn Carolyn Johnson Washington Post 202-334-6248 (desk) ----- (b)(6) (cell) From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 15 Apr 2020 0 1:35:53 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Call w ith VP and Senators on Thursday 4/15 I guess in perso n since I will have to be down t here any way From: Conrad, Patricia (NIH/NIAID) (E] (b)( > Date: Tuesday, Apr il 14, 2020 6:13 PM To: Fauci, Anthony {NIH/ NIAID) (E] (b)(6) Subje ct: FW: Call w ith VP and Senat ors on Thu rsday 4/15 ------~~ (b) (5) From: Edwards , Sara L. EOP/OVP -------------------~~ Date: Tuesday, April 14, 2020 4:43 PM To: M cGuffee, Tyler Ann A. EOP/OVP (b) (6)> (b)( ; Good-Cohn, Mered ith (CM S/OA) (b)(6)>; Shirley.Gathers (b)(6) .,;_~~...:..!:======~;:----~-"'."""':=========~ (b)(6); Amerau, Colin C LT USN JSJ4 (USA) (b)(6) ,; Conrad, Pat ricia {NIH/NIAID) [E) (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E) (b)(6)>; Rom, Colin (FDA/OC) (b)(6)> Cc: Lankfo rd, Hannah A. EOP/OVP (b)( > Subject: Call with VP and Senators on Thursday 4/15 --------Good afternoon, Vice President w ill be joining a call with Senate Democrats on Thursday April 16 at 1:00pm. The call will be routed through the (b)(5) similar to last week 's call. Please have your principal dial into the (b) (5) at (b) (5) at 5 minutes prior to the start . They w ill be patched into the Vice President and then together into the Senate calls. 1PM-2PM Senate Demo cratic Caucus (b) (5l Pleaseconfirm your principal Thursday4/16 Secretary Steven Mnuchin, Department of the Treasury -by phone Administrator Seema Verm a, Center for Medicare and Medicaid Services {CMS) - by phone Dr. Anthony Fauci, Director, National Institute of Allergy and Infectious Diseases - by phone Dr. Stephen Hahn, Commissioner of Food and Drugs, Food and Drug Administration -by phone Rear Admiral John Polowczyk, Vice Director for Logistics, J4 - by phone Ambassador Debbie Birx, M.D ., White House Coronavirus Response Coordinator - in-person Thank you, Sara Edwards Office of the Vice President From: Date: (b)(6) Tue, 14 Apr 2020 13:55:46 -0400 To: Subject: Attachments : Lerner, Andrea (NIH/NIAID) [E) Fwd: Dr. Fauci- FROMNBC4 image001.png , ATTOOOOl.htm, manuscript final draft revised.pdf, ATT00002.htm Please check this out and respond as appropriate. Begin forwarded message: From: Melissa Moll et Date: April 14, 2020 at 10:22:13 AM EDT To: _____ > (b)(6) , "Fauci, Anthony "Fauci, Anthony (NIH/NIAID) [E]" (bH6) >, "Fauci, Anthony (NIH/NIAID) [E]" '---~~ (b) (6) , Melissa Mollet (b) (6) "Mollet, (NIH/NIAID) [E]" -------- (b) < (b)(6) , Melissa (NBCUnive rsal, WRC)" , Jeremy Schu lman Subject: Dr. Fauci - FROM NBC4 Hello Dr. Fauci, This is Melissa Mollet, reporter with NBC4 in Washington. I hope you are well and safe - and are hanging in there during this unprecedented time. You have been doing an incredible job. I know you 're ge ttin g a million emails, so my apo logies in advance. I really th ink this information (attached and below) could help and I feel a re spon sibility to pass it along . There is an extremely promising COVID-19 therapy being used right now in Italy. The creator is a client o (b) (6) Bethesda law firm. The managing member of that firm, Jeremy Schulman, is CC'd on this e-mail. The creator is willing to work with the NIH to quickly bring his therapy to the U.S. Please reach out with any questions at all. BestMelissa Molle t NBC Washington 400 1 Nebraska Avenue NW Washington, D.C. 20016 (b)(6) (Cellular) Get Outlook for iOS ----- From: Jake Schaller Date: Monday, April13, 2020 5:36 PM To: Mollet, Me lissa {NBCUniversal, WRC) Subject: [EXTERNAL]Therapy for COVID-19; Results of Trial in Italy Melissa, I wanted to expand a bit on the COVID-19 therapy I mentioned and provide some information about the man who is developing it . Hoping that you can get this into the right hands, as it seems like a very promising lead in this fight . The therapy, invented by Professor Claudio De Simone, has shown extremely encouraging results in a preliminary trial at the Infectious Diseases Clinic of the University "La Sapienza" in Rome, Italy . Professor De Simone convinced the doctors there to start a trial on patients affected by COVID-19. Considering the excellent results obtained, the number of patients enrolled is increasing day after day. Our firm became aware of these results directly from Professor De Simone, who has been a client of our managing partner, Jeremy Schulman, since 2015. The formulation employed in these patients at the La Sapienza Infectious Diseases Clinic is manufactured in France and known as "SIVOMIXX." The product is a specialized blend of eight different freeze-dried bacteria with considerable ant iviral and anti-inflammatory activity. Patients admitted to the clinic at La Sapienza, presenting as positive for COVID-19 and with the typical symptoms of the disease, are being treated by oral bacteriotherapy utilizing SIVOMIXX. In each case, SIVOMIXX administration was followed by a dramatic improvement in their conditions. The key takeaways are that use of SIVOMIXX correlated with fewer deaths (zero in the treated group), fewer patients transferred to the ICU, and a dramatically reduced risk of patient intubations . The sponsors of the trial using SIVOMIXX are now beginning to enroll patients with severe cases who have been admitted to the ICU. Attached to this email is a confidential dossier about the SIVOMIXX product and a summary of the ongoing study. Upon request, I am also able to send you an Excel file containing the raw data from the study, so NIH can review them, with the understanding that this should be treated as "highly confidential." Since the clinical tria l is continuing in Italy, we expect to have results covering additional patients on a rolling basis. The researchers conducting the study intend to publish their results in the coming weeks. However, considering the pandemic and the lack of effective treatment options, we want to make NIH aware of Professor De Simone's therapy without any delay. SIVOMIXX is a relatively new formulation developed by Professor De Simone, currently in limited commercial production at a manufacturing facility in France. Professor De Simone has sufficient supply available to utilize with 100-150 COVID-19 patients immediately. Professor De Simone could, on his own, arrange a small-scale supply to use with hundreds of additional patients in the United States. He is willing to provide his current inventory of the product to the United States government. He expects that the Trump administration could quickly confirm the efficacy of SIVOMIXX to significantly improve symptoms of COVID-19 and reduce the duration of patient hospital stays. After that , Professor De Simone is willing to collaborate with the administration to bring a large-scale production of SIVOMIXX for use throughout the United States, Italy (where he was born), and Switzerland (where he lives). Professor De Simone already has ongoing partnerships with a number of manufacturing companies, including one in the United States, for the production of another one of his produc ts (Visbiome, referenced below). With appropr iate guidance and instruction from the Trump administration, we believe the U.S. manufacturing companies could re-tool to produce SIVOMIXX on a large scale within several weeks . Professor De Simone (more information about him below) and Jere my will do whatever it takes to bring this critical therapy to as many Americans as possible on an urgent basis. Jeremy can be reached at anytime on his cell phone (b)(6) Thanks so much for passing this on. Best, Jake About Professor De Simone. Professor De Simone is a world-renowned expert in gastroenterology and the inventor of several highly successful probiotic medical foods. Until 2010, he was an Associate Professor for the Infectious Diseases Group at the Department of Medicine and Surgery of the University of L'Aquila, Italy. Subsequently, he was appointed Head of the Infectious Disease Department and Director of the AIDS Coordinat ion Group of the Abruzzi region, Italy. He is currently a retired Professor of Internal Medicine, still collaborating with the University, and a Fellow of the American Gastroenterology Association . Professor De Simone's research specialt ies have been in the fields of immuno -pathogenesis of infectious diseases. He has published the results of his research activities in over 200 scientific articles, reviews, case reports, and book chapt ers. Professor De Simone is both a researcher and a medical practitioner. He tests his laboratory hypotheses in the university hospital clinic on patients w ith serious diseases. He was responsible for controlling the AIDS pandemic in Italy's Abruzzi region in the 1990's. Products developed according to Professor De Simone's know-how have shown positive results in patients with serious diseases. One of his signature formulations , known as the "De Simone Formulation," is now sold in the United States as "Vi sbiome ." The De Simone Formulation has been the subject of more than 70 published huma n clinical trials demonstrating its efficacy in managing severe gastrointestinal symptoms from such diseases as ulcerative colit is, pouchitis, and liver diseases. Concerning pouchitis, the De Simone Formulation is recognized by the world's professional gastroenterology societies as a "standard of care," an achievement that no other probiotic substance previously has attained. The De Simone Formulation became the "gold standard" in its therapeu ti c class. Its role in patient care has been endorsed in the guidelines published by the American Gastroenterology Association ("AGA"), the European Crohn's and Colitis Organization ("ECCO" ), and the British Society of Gastroenterology, as well as in t he New England Journal of Medicine . SCHULMAN BHATTACHARYA James "Jake" Schaller Attorney j schaller@schulmanbh.com www.SchulmanBH.com Direct: (240) 356-9508 Cell: Cb> (6) Main Office: The Clark Building 7500 Old Georgetown Road , Suite 901 Bethesda, Maryland 20814 Receptioni st: (240) 356-8550 Fax: (240) 356-8558 Bio-Tech Corridor Office: The GSK Building 14200 Shady Grove Road , Suite 600 Rockville, Maryland 20850 The informa tion contained in this electronic message and any attached documents may be privileged, confident ial, and protected from disclosure . If you are not the intended recipient, please note that any review, disclosure, copying, distribution, or use of the contents of this electronic message or any attached documents is prohibited. If you have received this communication in error, please destroy it and notify us immediately by telephone (240-356-8550 ) or by electronic mail to the sender of this email. Thank you. Internal Revenue Service Circular 230 Di sclosure: Schulman Bhattacharya , LLC does not provide tax advic e. In comp liance with IRS requir ement s, you are on notice that any adv ice contained in th is communication (including any attachments) is not intended or written to be used, and cannot be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party, for tax purposes, any transaction or matter addressed herein. From: Date: To: Cc: Subject: All the best, Mike What do you think? Fauci,Anthony (NIH/NIAID) [E) Tue, 14 Apr 202016:15:32 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch,Kimberly (NIH/NIAID) [C] FW: Mike Milken new Podcast Series: COVID-19- will you join me as my guest? Let us discuss. From: Michael Milken (mmilken@knowledgeu.com) Date: Tuesday, April 14, 2020 5:16 AM To: Fauci,Anthony (NIH/NIAID) (E] (b)(6)> Cc: Billie Griffin (bgriffin@knowledgeu.com) ; Katie Dinsmore (kdinsmore@knowledgeu.com) Subject: Mike Milken new PodcastSeries:COVID-19- will you join me as my guest? All the best, Mike ------ ~~ Dear Tony , I hope this email finds you well. I wanted to see if you had a few minutes to talk over the next few weeks. I recently began hosting a daily podcast that focuses on the COVID-19 pandemic and responses from thought leaders across industries - I would like for you to join me as my guest. I have also reached out to Hugh Auchincloss as well but still waiting to hear. Our guests so far include Francis Collins, Alex Gorsky, David Baltimore(Nobe/ Laureate}, Jim Allison(Nobe/ Laureate)/Pam Sharma, Jo Ann Jenkins, Eric Schmidt, Rod Hochman, Carmine Di Sibio, Arie Belldegrun, Peggy Hamburg, Rodney McMullen, Bruce Broussard, Vas Narasimhan , Joe Tsai, Steve Ballmer, Jeff Skoll, Sue Desmond-Hellmann, Rob Manfred, Judy Faulkner, Bob Bradway, Tai Zaks, Ray Dalio, David Solomon, Barbara Humpton, Dr. Steven Rosenberg, Dr. Richard Stone, Dr. Kurt Newman, Vivek Ramaswamy, Francis deSouza I record the interviews on Mondays, Wednesdays-Fridays start ing at 7:30 a.m. Pacific/10 :30 a.m. Eastern. Each episode will last 10-20 minutes . Our team would get you set-up to join remotely by phone. Th e inte rvi ews are available on the Milken Inst itute website as well as on Spotify and Apple Pod casts .. I opened up the series with Francis Collins a few weeks ago, click here to have a list en. If you're interested in joining me, my team (copied) will circle back to you with another email detailing the subject matter and technical informat ion. Please stay safe & healthy. All the best, Mike (b)(6) From: Date: To: Subject: Tue, 14 Apr 202010 :32:21-0 400 Tengiz Tsertsvadze Re: US-Georgia biomedical collaboration Tengiz: Thank you for your kind note . I am pleased to see that Georgia has controlled the outbreak very well. Stay well. Best regards, Tony On Apr 14, 2020 , at 10:24 AM, Tengiz Tsertsvadze -------- (b)(6) ,>wrote: Dear Dr. Fauci, I am writing this letter on behalf of the community of infectious diseases specialists of Georgia to express our deepest respect to you. I recall with great pleasure all our previous meetings, espec ially the last one in 2017 , when 1, together with my team members , had an opportunity to visit you at NIH. We are grateful to you and your team for the most important contribution to establishing US-Georgia biomedical collaboration that significantly increased our country's research and practical capacities. Your personal role in combat ing HIV and other emerging epidemics such as SARS , MERS , Zika, Ebola, canno t be overestimated. I am confident that your leading role in this fight against COVID-19 will be crucial for defeating the pandemic not only in the United States, but around the globe. We close ly follow your briefings and interviews on COVID-19 (including recent very interesting convers ation with Dr. Howard Bauchner at JAMA) and as always your views are very apt and to the point. We fully agree that the approaches you suggest are the mos t effective way to defeat the pandemic. Most importantly your recomme ndations are applicable not only to the United States, but to other countries as well and we eagerly take them into considerati on while planning our strategies here in my country of Georgia . I would like to use this opportunity to upd ate you on COVID-19 situation in my home countty of Georgia : The country quickly responded to this threat fu st by stopping flights with China in January, followed by more strict measures after the first case was diagnosed on February 26. These measures included national lockdown , active contact tracing, isolation and quarantine . The Government of Georgia appointed me to lead the Nat ional Committee on the clin ical management of COVI D- 19. Our effort to contain the spread of the virus had been effective so far with 296 cases of COVID-19 and 3 lethal cases reported up to now . We are impatiently awaiting results of vaccine and therapeutic trials supported by NIAJD, which I am confident will help to defeat this pandemic disease . On our side, Georgia is committed to make its modest but important contrib ution to the global efforts. Sincerely, Tengiz Tsertsvadze , MD, PhD Director General , Infectious Diseases, AIDS and Clin ical Immunology Research Center Professor of Medicine , I vane Javakhishvili Tbilisi State University From: Date: To: Subject: response Attachments: Fauci, Anthony (NIH/NIAID) [E] Tue, 14 Apr 2020 03:29:04 +0000 Lerner, Andrea (NIH/NIAID) [E] FW: Covid- 19 logical treatment strategy based on patient's immunological MEDRXIV-2020-058420v1-Gali Filho.pdf From: Julio Gali (b)(6) Date: Monday, April 13, 2020 12:34 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-:)(=6) Subject: Covid-19 logical treatment strategy based on patient's immunological response Good afternoon Dr. Anthony Fauci. After reading a lot of papers and studying basic science we have elaborated a treatment approach to the disease. (b)(4) (b) (4) Julio C. Gali Filho, MD Research and Development, JJMED,Sorocaba, SP, Brazil (b)(6) (b)(6) Julio C. Gali , MD , PhD Department of Orthopaedics Faculty of Medical Science and Health Catholic Un iversity of Sao Paulo Sorocaba/SP- Brazil (b)(6) (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 14 Apr 2020 02:13:45 +0000 Hiatt, Fred RE:fred checking in Fred: Thank you for you kind note. Am glad to hear that Joe is working on COVID-19. We need all the brightest minds we can get on th is problem. Stay safe and well. Best regards Tony From: Hiatt, Fred Date: Monday, April 13, 2020 2:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: fred checking in ---------=-:-= --------(b)(6) Tony, I haven't wanted to bother you, but wanted to say thanks for all you are doing, and hope you are at least to a small extent finding a way to take care of yourself . H is hard at work at (b)(6)on a couple of coronavirus projects, so we're counting on him. Of course any time you want to write something, our page is available . Warmly, Fred From: Date: To: Cc: Fauci, Anthony (NIH/N IAID) [El Tue, 14 Apr 2020 02:03:49 +0000 Glass, Roger (NIH/FIC) [El Kilmarx, Peter (NIH/FIC) [E];Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC Subject: RE:Support for a "U.S. COVID-19 Response Corps" Great idea!! ------- From: Glass, Roger (NIH/Fie) (E] (b) (6)> Date: Monday, April 13, 2020 12:50 PM ------ --~ To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) ,_;_:....;;.=:::===,~~"""."".".'~ Cc: Glass, Roger (NIH/FIC) [El______ Cb _~_ < >; Kilmarx, Peter (NIH/Fl() [E] (b) (6) > Subject: Support for a "U.S. COVID-19 Response Corps" Hi Tony, Greet ings from --------------------- (b)(6) It's been good to see all the calls for ramping up a public health workforce to manage contact tracing and other aspects of the second phase of the response. I wanted to let you know that Peter Kilmarx has been calling for the formation of a "U.S. COVID-19 Response Corps" since March 21 (unrelated to NIH work). FEMA could hire thousands of tempo rary workers quickly with existing authorities and funding. CDCcou ld provide training and technical assistance. The workforce would be deployed to and managed by state and local health departments at their request. There's a lot of enthusiasm for this from Jeff Duchin in Seattle, to Tom Frieden, CSIS, ASTHO, and 40 mem bers of Congress (bicameral, bipartisa n) who sent a letter to FEMA asking them to do this. The 7,000+ recently evacuated Peace Corps volunteers could be one recruiting source. Anoth er approach is for CDCto fund state and local authorities for those who are able to hire at this speed and scale. There's more information in the string below. This workforce issue is now sucha critical part of the response, I wanted to share with you what we've learned and offer to help in any way. Tony, all of NIH is so proud of your leadership and rooting for you to get this outbreak under con trol. Please keep up fight and let us know if and how we can help. Warm w ishes, Roger From: Kilmarx, Peter {NIH/FIC) [E] Date: Monday, April 13, 2020 8:45 AM To: 'Conover, Craig' Burnett' ------- (b)(6J>; 'Duchin, Jeff' (b)(6) 'Angela Dunn' ---------- 'Cindy (b)(6Ji>;'Stephen Morrison' (b)(6) (b)(6)j>; 'Charles Holm es' (b)(6)l>; 'John Monahan '! (b)(~' (b)(~>; 'Jeremy Konyndyk I (b)(6)j;'Tom Inglesby' (b)(<> ~>; 'Rebecca Katz'( (b)(6)]>;'Glenn Blumhorst' I (b) <6>t>; Glass, Roger (NIH/FIC) [El (b)(6)j>;'Marcus Plescia'I (b)(6>;>; 'Vanessa Kerry' (b)(6)Jg>; 'Kenyon, Thomas' (b)(6)j>; 'Anna Carro 11' (b)(6)l>; 'Scott Dowell' ! (b)(6l>; 'Jonathan Pearson' (b)(6)j>; 'O'Connor, (b) (6));'suzannemarks@me.com ' (b)(6)]>;'Robyn n Leidig' Eileen' ! (b)(6)]>;'Myers, Michael' ! (b)(6)j>; 'Ariel Pablos'I (b)(~; 'Gavin Varney' (b) (6)J>; 'Jody Olsen' I (b) <6 ~>; Bialy, Kevin ( NIH/FIC) [E] (bT(lih; Brooks, John T. (bH6)j>;'John Auerbach ' (b)( 6)>; David (CDC/00I0/NCHHSTP/DHPSE)I (bH6>i>;'Dara Lieberman ' ! (b)(li);> Gittelman I Subje ct: RE: COVID-19 Response Corps r .r- Hi all, Updates: 1. Johns Hopkins and ASTHO released "A National Plan to Enable Comprehensive COVID-19 Case Finding and Contact Tracing in the U.S." calling for 100,000 contact tracers . (Kudos!) "Potential workforce recruits may include ... Peace Corps members. http://www.centerforhealthsecurity.org/our-work/pubs archive/pubs-pdfs/2020/a-nationalpla n-to-enable-comprehens ive-COVI0-19-case-fi nd ing-a nd-contact-tracing-i n-the-US. pdf 2. WaPo article : "A plan to defeat coronavirus finally emerges, but it's not from the White House" covers the JHU/ASTHO plan and notes: "Experts [CSIS]have proposed transforming the Peace Corps into a nat ional response corps that could perform many tasks, including contact t racing." (Not quite accurate. Peace Corps would be unchanged, but the evacuated volunteers would be hired into COVI0-19 response.j 3. NY Times editorial from Tom Frieden calls for a "giant public health effort ." "Recruits could include Peace Corps volunteers who were brought home when the pandemic spread." https:l/www.nytimes.com/2020/04/12/opinion/cdc-coronavirus.html 4. Bill introduced by Sens. Susan Collins (R-ME), Chris Murphy (D-CT) and Dianne Feinstein (D-CA) would require federal agencies and departments facing special hiring needs during the pandemic to establish a process to expedite hiring of returned Peace Corps volunteers https ://riponadva n ce.com/stories/ col Iins-bi partisa n-bill-wou ld-e nsu re-benefi ts-for-evacuatedpeace-corps-vol unteers/ 5. From March 29: Policy report from former FDA Commissioners Scott Gottlieb and Mark McClellan calls for "massively" scaling contact tracing. "Surge the existing public-health workforce to conduct case finding and contact tracing." https;//www.aei.org/researchproducts/report/na t ional-coronavirus-response-a-road -map -to-reopening/ 6. Mark McClellan responded to my email yesterday: "I'd suggest adding outreach to mayors and county execs if that hasn't happened yet. They are really on the front lines for this next phase." 7. I understand legislation is in the works, but don't have details. 8. No news from FEMA or indicat ion to my knowledge that they are planning a substantial ramping up of staffing. 9. A key limitation on the impact of contact tracing will be the relative importance of asymptomatic spread. 11 10. A note on serology: The current U.S. cumulative incidence is 0.169%. The specificity of FDA EUA Cellex test is 95.6%. Not accounting for undiagnosed cases, Positive Predictive Value is only 3.5%. If underdiagnosis is 10:1, the PPVis sti ll only 26.8%. Will be higher in higher-risk individuals, of course. Any other updates please send to me. Advocacy needed for scaling up public hea lth work fo rce especially wit h governors and mayors. PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Friday, April 10, 2020 1:53 PM (b) (6)\;'Cindy To: 'Conover, Craig' ( (b)(6J;>;'Angela Dunn' ! Burnett' ( (b) C6J i>; 'Duch in, Jeff (b)(6),>;'Stephen Mor rison' (b)(6)]>; 'Charles Holm es' (b)(6);>; 'John Monahan '( (b)(6)j)' Cb)(6)};'Jeremy Konyndyk CbH6)j>;'Rebecca Katz'I CbH6)};'Tom Inglesby' (b)(6)1>; 'Glenn Blumhorst' I (b)(6):>; Glass, Roger (NIH/FIC) [E] (b)(6Ji;'Marcus Plescia'I (b)(6)t>; 'Vanessa Kerry' (b)(6)};'Anna Carrol I' (b)(6)1>; 'Kenyon , Thomas' ! (b)(6)J>; 'Scott Dowel l'r (b)(6)j;'Jonathan Pearson' (b) (6)]>; 'O'Connor, (b) (6)1>; 'suzannemarks@me.com ' (b)(6) 1>; 'Robynn Leidig' (b)(6)}>; 'Myers , Michael' r (b)(6)h; 'Ariel Pablos'f (b)(6)}; 'Gavin Varney' (b)(6)j >; 'Jody Olsen' I (b)(6)1>; Bialy, Kevin (NIH/FIC) [E] (b) (6Jf;Brooks, John T. CbH6)};'John Auerbach' I (b)(6)j> (CDC/OO1O/NCHHSTP/DHPSE )I (b)(~; 'Dara Lieberman ' ( Subject: RE: COVID-19 Response Corps r + John Auerbach, president and CEOofTrust for America's Health Thanks all for the robust discussion. Some updates: 1. ASTHOsent the attached memo t o Congress today RE: Contact Tracing Workforce calling for "flexible long term and emergency supplemental funding to expand the .. . contact t racing workforce" at state, local, and related levels. It recommends against using FEMA for hiring. ASTHOnotes tha t currently there are only 2,200 DIS nationw ide while JHU estimates that 100,000 contact tracing employees are needed to address COVID-19 in the immediate future. The memo mainly calls for 1) $3.6 B emergency funding through the CDCCrisis Cooperative Agreement to eligible jurisdictions, plus 2) a $4.5 B annual Public Health Infrastructure Fund. 2. Resolve to Save Lives (Tom Frieden) is advocating for CDCto have the needed authority and political support to provide tra ining, systems, and technical expertise, while the CDC Foundation and ASTHO provide staffing through direct assistance to health departments . 3. CDCcould support cur riculum development and training through the National Network of STD Clinical Prevention Training Centers https://nnptc .org/ and/or TB Centers of Excellence https://www.cdc.gov/tb/ education/tb coe/defau lt .htm My take: We share the goal of rapid ly and substantially ramping up the public health workforce and should emphasize that message. It would be very challenging for any of these potential approaches to reach 100,000 in the short term. I don't have any special allegiance to FEMA, but their traditional role in emergency response is quickly hiring many thousands of workers. They are hiring now, but not at this speed and scale. CDC and FEMA should have an MOU through which FEMA can hire staff and detail to CDC, bu t they don't seem to be pursuing. One model could be FEMA detailing staff to state and local authorities to manage the hiring process. FEMA is proud of their ability to get people from "door to desk" in one week . This would not be "federalizing" contact tracing or other public health activities. In all cases, the invitations and the oversight wou ld come from the state and local authorities, who are best able to decide what mechan ism(s) work for them. Lastly, this concept includes more than contact tr acing. Congresswoman Susan Brooks (R-IN) in her podcast Wednesday noted that the state 211 call line has gone from 2,000 to 25,000-35,000 calls per day. So this concept would still have a role even if not direct public health functions . Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Friday, April 10, 2020 8:05 AM (b) (6));Cindy Burnett (b)(6J,>; Angela Dunn ;Duchin, Jeff Cb)(6))>;Stephen Morrison CbH6))>; John Monahan ( (b)(6)j_>;Charles Holm es (b) (6))) (b) (6)}>; Jeremy Konyndyk I (b)(6)1>; Tom Ingles by (b)(6)];Rebecca KatzI CbH6))>;Glenn Blumhors t l CbH 6>i >; Glass, Roger (NIH/FIC) [E) CbH (i)J>;Marcus Plescia CbH 6)j>;Vanessa Kerry CbH6))>; Kenyon, Thomas [ CbH6)); Anna Carroll (b)(<>Jt>; Scott Dowell ! CbH6l>;Jonathan Pearson (b)(6)j;[ Cb)(6));O'Connor, Eileen Cb)(6)]>; Myers, Michael (b)(~>; Robynn Leidig CbH6))>; Ariel Pablosr CbH6))>;Gavin Yamey (b)(6)]>; Jody Olsen! CbH6))>;Bialy, Kevin (NIH/FIC) [E (b) (6)]> Subject: COVID-19 Response Corps - CDCcalling for public health army Thanks Craig. This NEJM articl e is main ly about heath care workers, but does mention ot her roles in social support. Important development : CDC's Bob Redfield is calling for a publ ic health army for contact tracing after this acute phase: https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressivecontact-tracing -needed-for -u-s-to-return-to -normal It turns out that the Centers for Disease Control and Prevention has been working on a plan to allow the U.S. to safely begin to scale back those policies . CDCDirector Robert Redfield spoke with NPR on Thursday, saying that the plan relies on not only ramped -up testing but "very aggressive" contact tracing of those who do test positive for the corona virus, and a maj or scale-up of per sonnel to do the necess ary work. I'm not sure CDChas the authority, capacity, or politica l support to hire an army at this t ime . This is a t radit ional FEMA role. CDC can prov ide train ing and tec hnical assistance . PK From: Conover, Craig_________ Cb _H_6) Se nt : Friday, April 10, 2020 7:27 AM (b)(ij >; Cindy (b)(6),>; Angela Dunn 1 To: Kilmarx , Peter (NIH/FIC) [E]1 Burnett ( CbH6)]>; Duch in , Jeff I Cb)< ~ >; Stephen Mo rrison CbH6) 1>; John Monaha n :) (b)(6)J; Jeremy Konyndyk I (b)(6)]; Rebecca KatzI (b)(6)1>; Tom lnglesby (b)(6)]; Glenn Blumhors tl (b)(6)]>; Glass, Roger {NIH/Fl C) [El CbH6)];Marcus Plescia( (b)(6)j>; Vanessa Kerry Cb)(6)]>; Kenyon, Thoma s! CbH6)]>; Anna Carroll Cb)(6)]; Scott Dowell (b)(6)]>; Jonathan Pearson Cb H6)]O'Connor, Eileen (b)(6)J>; Myers, Michae l I CbH6l>; Robynn Leidig Cb)(6)1>; Ariel Pablos r CbH6)]>; Gavin Yamey (b)(6)] Subject: NEJM- ensuring and sustai ning a pandemic workforce attached Fro m: Kilmarx , Peter (NIH/FIC) [E]_______ Cb _H_6)> Date: Wed nesday, April 8, 2020 5:53 PM (b)(6), ; Angela Dunn I Cb)C 6)]; Cindy Burnett To: Conover, Craig( (b)(6)>; Stephen Morrison CbH6)]>; Duchin, Jeff ( (b)(6)]>; John Monaha n( (b)(6))>; Charles Holmes (b) (6)]) Cb)(6)1>; Jeremy Konyndyk r (b)( 6)1>; Tom lnglesby (b) (~ >; Rebecca KatzI (b)(6)1>; Glenn Blumhors tl (b)(~ >; Glass, Roger (NIH/FIC) [El (b) (6)]>; Vanessa Kerry (b)(6)]>; Marcus Plescia! CbH6)]>; Anna Carroll CbH6)]>; Kenyon, Thomas ! (b) (6h ; Scott Dowell CbH6>: >; Jonathan Pearson (b)(6)j O'Connor, Eileen( Cb)(6)]; Mye rs, M ichael I CbH6)]>; Robynn Leidig CbH6)]>; Ariel Pablosl CbH6)]>; Gavin Yamey (b) (6)1> Subject: [Extern al] RE: UPDATE:COVI0-19 Response Corps Welcome Marcus Plescia, chief med ical officer of ASTHO! Updates: 1. CSISpodcast "Coronavirus Crisis Update" with Congresswoman Susan Brooks (R-IN). She cosigned the CSISOpEd with Ami Bera on the CRCand opens the episode with a discussion of engaging the returned Peace Corps volunteers httos://www.csis.org/oodcasts/takedirected/coronavirus-crisis-update-hunker-down-hoosiers -congresswoman-susan-brooks (This is a great series by the way.) 2. On Mar 27, 2020, Congressman Mike Quigley (D-IL-05) introduced the Mobilizing America to Help Act, "which would direct President Trump to invoke his existing authority to detail Peace Corps vo lunteers who have returned to the US from their posts, to the Federal Emergency Management Agency (FEMA) to support emergency relief in the wake of COVID-19." https:l/guigley.house.gov/media-center/press-releases/guigley-urges-trump-assign-peacecorps-volunteers-covid-19-emergency 3. Baltimore Sun column DAN RODRICKS,APR 03, 2020, "Put Peace Corps volunteers to work on U.S. soil to fight COVID-19": https://www.baltimoresun.com/op inion/co lumnists/danrodricks/bs-md-rodricks-0405-20200403-viqbgjhwsnhe3fuqzy72nfcsoe-story.html 4. Good conversations w ith Marcus @ASTHOand others today. Important to emphasize that state and local authorities have the lead. This would not be "federaliz ing" the response. It would be making federal employees available by request to integ rate in state- and local-led activities. Some will welcome the extra hands. Some will prefer to have funding to do their own hiring. Paying salaries of state employees at risk for furlough to work on COVID-19 w ill make a lot of sense, but won't be enough. Need a menu of options . 5. Many concepts and plans for public health and social response are being circulated. All of them will need an expanded workforce. Outreach: 6. I'm in touch with someone in Adam Boehler's office . Other outreach welcome. 7. I emailed Peggy Hamburg. No reply yet. Other outreach welcome. 8. Anyone who can contact Scott Gottlieb? 9. Here again is Monday's list: NGA and individual governors. Republicans who will be most interested and helpful are Baker {MA),DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer, lnslee. AMA, ASTHO (done), APHA all good potential champions Please amplify these links on social media. Other updates and suggestions welcome as always. Send to me and I can send to others in a digest to reduce email traffic. Thanks, PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, April 7, 2020 8:19 AM (b)(6)>; 'Angela Dunn' To: 'Conover, Craig'< Burnett' (b)(6)>; 'Duchin, Jeff (b)(6J_>; 'John Monahan' (b)(6b; 'Jeremy Konyndyk (b)( 6), ; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' ----==~~;--:-:---:---- (b)(6) 'Cindy >; Stephen Morrison (b)(6J t>; 'Charles Holmes' (b)( ----========~~:-" =======~~-:--~---======~~----:_.!:=========~~------- (b)(6)' 'Tom lnglesby' Glass, Roger (NIH/FIC) (E] (b)(6); (b)(6J>; ' (b)(6) 1>; 'Vanessa Kerry' (b)(6) · 'Kenyon, Thomas ' ...:=========-.;....,:-:--:-= ""---:-:-:--.:=======:~;-'.":'"""' (b)(6); 'Anna Carroll' (b)( >; 'Scott Dowell' CbH6)>; 'Jonathan Pearson' CbH6)>; ---~:-:":""-:.========...;_ -=-,-= (b)(6) CbH6); 'O'Connor, Eileen' (b)(6) ----~~-===:!.=====:=~~""".""_...:_ __ ..!:::=====:=.~~-'Myers, Michael' 'Robynn Leidig' >; 'Ariel (b)(6)>; _:..__.....:::..::=~~------(b)( PabIos' (b)(6)>; 'Gavin Varney' Subject: UPDATE: COVID-19 Response Corps - FEMA challenges (b)( > Here's a report about a challenge I didn't see until this morning. I don't know if grants to state and local authorities would be quicker than federal hiring by FEMA. Either way, the workforce is needed, but will take longer than one would like. https://www.nytimes.com/2020/04/03/climate/fema-staff-s hortage -coronavirus.html FEMA, Racing to Provide Virus Reliet Is Running Short on Front-Line Staff WASHINGTON- The Federal Emergency Management Agency, the office leading the federal government's coronavirus response nationwide, is running short of employees who are trained in some of its most important front -line jobs, according to interviews with current and former officials. At the same time, the agency has been forced to halt a major hiring initiative, and has closed training facilities to avoid spreading the infection. The number of available personnel who are qualified to lead field operations has fallen to 19 from 44 in less than six weeks, and staff members have been pulled from responding to other disasters, but training centers in Maryland and Alabama have been shuttered until mid-May . In addition, an effort to recruit new employees called "Harness" is on hold, according to a senior administration official with direct knowledge of FEMA's operations . ... Craig Fugate, who ran the agency during the Obama administration, said FEMA's ability to deploy enough people was a significant challenge. "Can it be done? Yeah," Mr. Fugate said. "Will it be pretty? No." From: Kilmarx, Peter (NIH/FIC) [E) Se nt : Monday, April 6, 2020 5:22 PM To: Conover, Craig ____ (b)(6) ,>; Angela Dunn (b)(6)>; Cindy Burnett ;___; ~~~-:--""".""'"'::-:-====~.....:::....... _ __,~~--:--""""'.""~"":"'""- (b)(6); Duchin, Jeff (b)(6); Stephen Morrison =====~~:;--" --:;:::::::=========~~ = Charles Holmes (b)(6)>; John Monahan (b)(6); (b)(6) >; Jeremy Konyndyk (b)(6) ...:========-~~-=--:--(b)( >; Rebecca Katz (b)(6) Tom lnglesby =====~~-':""".""' --!============:~~ ===== (b =) ~(6)~ >,;,; Glenn Blumhors t Cb)( ; Glass, Roger (NIH/FIC) [E) (b)(6); Vanessa Kerry (b)(6)>; Kenyon, Thomas :'.i========~~ (b)( 6) >; Anna Carroll ----:-:.:::::=======:~;--(b)( >; Scott Dowell (b)(6) Cb)(6)>; Jonathan Pearson ...:::======~~;-:-:-:--(b)(6) O'Connor, Eileen (b)(6)>; Myers, Michael ========~ _______ =====~~ (b)( >; Robynn Leidig _, Gavin Varney (b)(6)>; ........ :==========::,_;,. ~ Ariel Pablos (b)(6) (b)( Subject: NEWS: Bera-Brooks OpEd published in support of COVID-19 Response Corps Welcome Vanessa Kerry! Welcome Ariel Pablos-Mendez! Welcome Gavin Yamey! Hi all, 1. The OpEd is out on the CSISwebsite: https://www.csis.org/analysis/covid-19-response-corpscan-help -stop-pandemic It is co-authored by Congresswoman Susan Brooks (R-IN) and Congressman Ami Bera (D-CA), members of the CSISCommission on Strengthening America's Health Security. Thanks very much to Steve Morrison for making this happen. 2. Here's the link to the press release on the 40-member letter to FEMA, Peace Corps, and CNCS from Senator Van Hollen: a. https ://www. vanhol len .senate.gov /news/press-releases/ sen-van-hol len-rep-ph ill ips1ead-bi pa rti san-bicam era1-1 etters- in-su pp ort-of-pea ce-co rps-am eri co rps-volunteers b. Includes link to letter: vanhollen.senate.gov/imo/media/doc/Peace%20Corps%20covid19%20service%20oppor tunties%201etter%2004.02.20.pdf Wi th this new, bipart isan OpEd, it's time to reach out to national, state and local author iti es and opinion leaders to encourage implem entati on and create demand. Suggestions from one of us: NGA and individual governors. Republicans who will be most interested and helpful are Baker (MA), DeWine (OH) and Hogan (MD). Democrats: Cuomo, Pritzker, Newsom, Wh itmer , lnslee . AMA, ASTHO, APHA all good potential champions . Please also amplify on socia l media. Updates and suggestions welcome as always. PK From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, April 5, 2020 8:45 AM (b)(6)]; Cindy Burnett To: Conover, Craig( CbH6)];Angela Dunn I (b)(6); Duch in, Jeff ; Stephen Morrison Cb)(6}]_; John Monahan I (b)(6)J>; Charles Holm es (b) (6),) (b)(6)J>; Jeremy Konyndyk ~ (b) (~>; Rebecca Katz I (b)(~>; Tom Ingle sby (b) (6}]_>; Glenn Blumhors t q (b)(6) 1>; Glass, Roger (NIH/Fie) [E) (b)(~ Anna Carroll Cb)<6>i; Kenyon, Thomas I Cb)(6);>; Scott Dowell CbH6):>;Jonathan Pear son CbH6) l; O'Connor, Eileen (b)(6)l >; Myers, Michael I Cb)(6)1;Robynn Leidi g (b)(~ > Subject: UPDATES: Next steps on COVID-19 Response Corps Thanks all for our call Friday. {Glenn, Jonathan, Craig, Jeremy, Roger, Anna, Suzanne, Eileen, Michi2iel.) A few items from the call: • Jonathan reported Sen Markey's office working on legislation for 10,000+ (?) response workforce • Michael reported positive response from National Governors Association • Eileen reaching out to Tom Bossert. Adam Boehler not yet . Shared Op Ed in WSJ emphasizing test ing - https://www.wsi.com/articles/testing-is-ou r-way-out-11585869705 • Jeremy has an OpEd in Daily Beast with Beth Cameron https://www.thedailybeast.com/coronavirus-shows-we-need -an-apollo-project-for-publichealth • Craig in touch with Durbin's office. IL has ongoing need for large workforce. Much easier to get staff from feds. Slower to hire at state level. MA implementing 1,000-person contact tracing effort. • John in touch with Pelosi's office, Delaura, Conf of Mayors, League of Cities. • Other potential champions -AST HO, APHA, Josh Scharfstein @JHSPH • General agreement that for bipartisan emergency approval should emphasize near-term (e.g., 2 year) impe ratives of COVID-19 and economic emergencies, not a new permanent wor k force. • General agreement that Peace Corps is the low-hanging frui t, but not all 7,000 RPCVswould do this and the need is much greate r. • CSISOpEd with Ami Bera (D-CA) and Susan Brooks (R-IN) coming out in Politico or CSISwebsite by Monday Other updates: • Telcon Friday with Brooks staffer. They are putting together legislation, ideally bipartisan w ith Bera. Now fully briefed on CRCconcept and potential implementation model. Clarified not duplicative of USPHS Ready Reserve Corps which is now authorized but not being implemented (to my knowledge) and would be different profile, i.e., USPHShas physicians, nurses, engineers, etc. • Telcon Saturday with CDCCOVID-19 Chief Medical Officer . Confirms many are thinking about the workforce issue. Notes that CDCunlikely to "own," but great suggestion to engage CDCfunded National Network of STDClinical Prevention Training Centers for training. https://nnptc.org/ with eight centers around the country. CRCconcept may be brought to national response discussions with FEMA in Washington DC. • FEMA contacts report they are hiring RPCVs,but do not report majo r speed up or scale up. FEMA recruiting email attached. • Charles shared Vanessa Kerry OpEd emphasizing same themes : response workforce and jobs: https ://www. boston hera Id.com/2020/04/01/ massachu setts-genera I-hospita 1-infectio usd isease-tea m-ca Ils-on-state-to-harness-people-power/ Next steps: • Executive - support/impetus to FEMA to increase speed and scale • Legislation - new appropriations for FEMA or CDCif needed • National advocacy- media, opinion leaders • Demand signal - state and local authorities requests • Implementation and management details working out Over all goal: Greatly increase COVID-19 response workforce to control disease and provide jobs. A COVID-19 Response Corps would be a (big) part of solution. RPCV ideal first cadre for CRC. Please share any corrections, updates, suggestions. Thanks, PK -----Original Appointment----From: Kilmarx, Peter (NIH/FIC) [E] Date: Thursday, April 2, 2020 5:34 PM To: Conover, Craig; Angela Dunn; Cindy Burnett; Duchin, Jeff; Stephen Morr ison; John Monahan; Charles Holmes; Jeremy Konyndyk (b)(6); Rebecca Katz; Tom lngl esby; Glenn Blumhorst; Glass, Roger (NIH/FIC) [E]; Kenyon, Thomas; Anna Carroll; Scott Dowell; Jonathan Pearson; (b)(6); O'Connor, Eileen; Myers, M ichael; Robynn Leidig Subject: * ** Time correction - 8 am**~ Next steps on COVID-19 Response Corps When: Friday, Apr il 3, 2020 8:00 AM-9:00 AM (UTC-05:00) Eastern Time (US & Canada). Wher e: Zoom meeting --------- Peter Kilmarx (Fie Zoom2) is inviting you to a scheduled Zoom meeting. Zoom link below. Agenda: 1. We lcome and introdu ctions 2. Current status of advocacy 3. Implementation issues 4. Next steps: a. Advocacy b. Implement ation 5. AOB Topic: Next steps on COVID-19 Response Corps Time: Apr 3, 2020 08:00 AM Eastern Time (US and Canada) Join Zoom Meeting (b)(4) Meet ing ID: ____ Cb> _C_4) One tap mobile +16465588656, }--- 4>us(New York) ~ (b~ H= +13126266799 ,J US (Chicago) Dial by vou r location CbH4J(New York) (Chicago) (Houston) (San Jose) Meeting ID: ----- (b) (4) Find your local numbe r: https://zoom.us/u/adl j8UhXNS From: Kilmarx , Peter (NIH/FIC) [El Date: Thursday, April 2, 2020 1:29 PM To: 'Conover, Craig' (b)(6) > ; 'Angela Dunn' Burnett' (b) (6); 'Duch in, Jeff (b) (6) ; 'John Mon ahan ' -----!==~~~~~· =======~~--:~ ,,.:....---========-~;-' (b:-) -(6J>; 'Jeremy Konyndyk CbH >; 'Rebecca Katz' (b)(6)>; 'Glenn Blumhorst' (b)(6)1>; 'Kenyon , Thomas' (b)(6) 'Scott Dowell ' =====~~----:~ (b)( 6)>; 'Cindy >; Step hen Morrison (b) (6J>; 'Charles Holmes' (b)(6)' (b)(6J>; 'Tom lnglesby' CbH6J>;Glass, Roger (NIH/FIC) [E] (b)( >; 'Anna Carroll' (b)( 6); (b)(6) --=========~~- ====-~ ~- ; 'O'Connor, Eileen' (b)( 6)> ---------- . (b)(6J>; 'Myers, Michael ' Subject: NEWS: Congressional letter to Peace Corps, CNCS,and FEMA on COVID-19 Response Corps Hi all, Big news. Herew ith is a letter signed by 40 members of Congress asking FEMA, Peace Corps, and AmeriCorps to form a "COVID-19 Response Corps." This is now in the publ ic domain. Press release forthcoming . Please save the t ime for Zoom call 8 am tomorrow on next steps. Also: Check out: http s://www.npr.or g/ sect ions/ goat sandsoda/202 0/04/0 1/8252 3 1838/co ron avirussent-p eace-corp s-vo lunteers -home -it-could-also-give-t hem-a-n ew-missi The National Peace Corps Association is hoping to create and fund a group that draws on the evacuated volunteers and their skills to respond to the COVID-19 crisis in the United States. Workers would take on work like tracing the contacts of diagnosed individuals, monitoring the hea lth of those in quarant ine and staffing call centers . An agency such as the Federal Emergency Management Agency, the U.S. Centers for Disease Control and Prevention or AmeriCorps could potentially manage the group, says Blumhorst, who has been advocating for the project. Salaries could come from funding that's already been allotted to the COV/0-19 response but hasn't yet been spen t. The NPCA has discussed the idea with the offices of several members of Congress that are receptive and support ive, Blumhorst says, and they're planning to speak with more congresspeople and federal agencies and also hope to draw public atten tion to this potent ial project. From: Kilmarx, Peter (NIH/ FIC) [E) Date: Sunday, Marc h 29, 2020 4:47 PM To: Conover, Craigl (b) (6J,>; Angela Dunn I (b) (~ >; Cindy Burnett CbH6)}>; Duchin, Jeff CbH6>; >; Stephen Morrison CbH6)/>; John Mona han! (b)(6)1>; Charles Holmes Cb)(6));Jeremy Konyndyk I Cb)(6)) (b)( 6))>; Rebecca Katz (b)( ~ >; Tom lnglesby CbH ~ >; Glenn Blumhors t Cb H6>i ; Glass, Roger (NIH/FIC) [E) (b)(6) ,> ; Kenyon, Thomas ( (b)(6)1>; Anna Carroll =====~~::""" "':::==========~ ~~ =======~~:::---"'.""""- =====.~;--~ ======~ =· -------- --========~~~ (b) (6); Scott Dowell Jonathan Pearson Subje ct: INFO: Update on COVID-19 Response Corps ----------------------- (b)( (b)(6) Hi all and thanks for your support for a U.S. COVID-19 Response Corps engaging returned Peace Corps volunteers (RPCV).The latest (March 26) 2-page concept note attached. Updates: l. Steve is working on getting the Op Ed out in press and/or on CSISwebsite by Tuesday . We'll let you know. 2. Glenn and Charles have found very good recep t ivity on the Hill. 3. I've had a couple very good calls with FEMA folks at senior levels (extensive RPCVnetwork) . They are already reaching out to RPCVand are well funded. They can get an RPCVon board in a week. They have a few different hiring mechanisms that would be appropr iat e. The scale and speed need to be ramped up substant ially. 4. I've reached out to contacts at nationa l mayors and governors associations with no reply. Also no reply from CDC (Jernigan and Schuchat). Next steps - when OpEd comes out, amplify multiple levels to publicize and create demand . The need for this is great. The feasibility looks very good . Please share you r suggestions . Thanks to all, PK From: Kilmarx , Peter (NIH/Fie) [El Date: Tuesday, March 24, 2020 6:02 PM To: Charles Holmes (b)(6) ; Angela Dunn (b) (6J_>;Cindy Burnett (b)(6)> ; Conover, Craig (b)(6) Duchin, Jeff (b)(6)> ; Glass, Roger (NIH/FIC) [El (b)(6J_>; Glenn Blumhorst --....!:=====~~ "".""."'--:---:::===========-~--(b_H_6); Stephen Morrison Monahan (b) < Subje ct: RE: Call - follow -up: COVID-19 Response Corps Hi again, A draft Op Ed attached . It is largely drawn from the concept note . Is there an appropriat e champion among us who can take thi s forward? Please share your suggesti ons and comment s by noon tom orrow if possible . Thanks, (b)(6)John PK From: Kilmarx, Peter (NIH/FIC) [E) Date: Tuesday, March 24, 2020 2:17 PM (b)(6)> .....;======~~--:-:---:--:-Cc: Angela Dunn (b)(6h ; Cindy Burnett (b)(6); Conover, Craig __ .:::__ __ --===::; (b:;: )(~6)-::D - u-c-:h-in-, J _eff , ,.--___:_ __ _,,!::===::a (b ~) ~ < " >-; ::: G:la-ss, Roger (NIH/FI C) [E] =====~=----::-:---===========-;___;__~....:..___:-;..,..;, (b)(6J>;Glenn Blumhorst (b)(6) To: Charles Holmes --------==Stephen Morr ison ':'"'":----:----"..:==========~;:;:;--:;;--(b)(6) (b)(6); John Monahan Subje ct: RE: Call - follow-up: COVID-19 Response Corps Thanks Charles. This is very helpful. I've updated the concept note - att ached. Now a two-pager. Added t raining and prevention bullet . Decreased t he numbers and budget based on feed back to date . Draft OpEd fort hcoming . Grate ful if others can advocate as they are able (and others of us are not ). Glenn - please add anything on your meetings on the hill yesterday, the FEMA call, or advocacy plans. My takeaway is that a FEMA disaste r corps or FEMA-Americorps Corps is feasible. • Call yest erday with Glenn and former FEMA staff : George Haddow and Miche al Coen o FEMA Corps is a partnership of FEMA and Americorps with about 1,200 -1,800 members . Part of Americorps. FEMA pays 100%. Mainly younger, lower-skilled supervised wo rk. o FEMA reservist disaster corps has 3,000 -4,000 members . Mostly sho rt er-term deployments as temp employees. Many retired military. Can be activated with State of Emergency declarat ions. o FEMA currently has sent 3-4 liaisons to each state. Disaster corps not activated. o Onboarding 5,000 would be a big lift. Peace Corps has seconded staf f to ot her agencies in past, so t his could be an option . o Only private sector partner for FEMA is Red Cross. Not recommended for this. • • Jen Kates (KFF)and her colleague Josh Michaud - "th ink it is a great idea" Tom Frieden -"It's a good idea." o Robynn Leidig, Manager, Strateg ic Init iat ives, Resolve To Save Lives - "Compelling idea and worth exploring" • Concern about risk to RPCVs,training and oversight needed • Lack of PPE, best to focus on tasks that don ' t need PPE • Resentment of current staff worried about threat to their jobs • Fairness: shou ld open to others - Amer icorps, VISTA,CDC PHAP,CSTE fellows, USAID Global Health Fellows • Manageme nt absor ptive capacity limited at CDC. Consider ASTHO/ NACCHOor PHI. More input: From: Charles Holmes ------------- (b)( 6) Date: Tuesday, Mar ch 24, 2020 7:36 AM To: Kilmarx, Peter (NIH/FIC) [El -------,; (b..,... )(=6)> Cc: Angela Dunn (b)( 6)> ; Cindy Burnett (bH >; Duch in, Jeff (b)( 6) ; Glenn Blumhorst Steph en Morr ison (b)(6) Subject: Re: Call - follow -up: COVID-19 Response Corps >; Conover, Craig __ ..;;;.. __ _::==~~---::-:-:->; Glass, Roger (NIH/FIC} [El ======~~---!:::=========~--:__..::...___:.__.:__~ .;, (b)( -------------------- (b)( 6) Sen Van Hollen' s office is interested and I'm slated to ta lk w them later today or tomorrow. Interested to know how the idea was received by others on the Hill. Best On Mon, Mar 23, 2020 at 7:44 AM Kilmarx, Peter (NIH/FIC) [El Thanks Charles. --------- (b)(6) wrote : Draft OpEd forthcom ing today. Everyone please think about autho rs. Bill Frist and Tom Daschle? https://w w w.rollca ll.com/2018/07 /09/op inion-an-open-health-diplomacyhand-works-bette r-than-a-fist/ ByTom Daschle and Bill Frist, July 9, 2018. From: Char les Holmes -----------Date: Monday , March 23, 2020 7:37 AM (b)(6)> ------~~ >; Conover, Craig _ _..: __ .;._~==~~-~ >; Glass, Roger (NIH/FIC) [El ...:======-~~-::-:-Kilmarx, Peter (NIH/FIC) [El (b)(6) ....,;._.;._......;...;....;.==~~-::---:--:-Cc: A ngela Dunn (b)(6); Cindy Burnett (b)( 6) > ; Duch in, Jeff (b)(6)>; Glenn Blumhorst Steph en Morr ison (b) (6)> Subject: Re: Call - fo llow -up : COVID-19 Response Corps To: (b)( 6) (b)( (b)(6J ; Great feedback, Peter . More from Vanessa Kerry: "Initial reaction is that this is fantastic and I would be happy to help in any capacity to support it. Please let me know how. Devil is in the details and t he training of course. Truly a smart idea though" Charles On Mon, Mar 23, 2020 at 7:11 AM Kilmarx, Peter (NIH/FIC) [E] -------- (b)( 6J> wrote: Thanks Craig. This looks very comprehensive and someth ing a trained RPCV(return ed Peace Corps Volun teer) could help imp lement. Glenn - good luck on t he Hill tod ay. Wil l be eager t o hear about the reception. Some feedbac k from others: • John Monahan (Georgetow n) - "Very creativ e, kudos!" o Try to get authority on one of these COVI0-19 response bills for returning Peace Corps folks to be redeployed notwithstanding other provisions of law. o Explore whether CRCcould be incorporated into the programs FEMA already has to bring in short-term employees to help with emergency responses. o Some functions (home-delivered meals, staffing call centers, home less populations and shelters) would more sense to supplement programs run by Americorps. o Cost seems high. • Scott Dowe ll (Gates Foundation) - "A good and important idea" o Need a massive surge in the public health and communi ty testing workforce over the coming mont hs. o They are considering engaging the 30,000 medical students through AMSA (American Medical Student Association) . • Tom lnglesby (Johns Hopkins) - "A fantastic idea and am very supportive" o Important issue to be worked through : How to address risk to individuals invo lved? (My response: training, equipping, and monitor ing. Will add to next iteration of concept note. Note that Singapore has had no infections in HCW and in China after January/Wuhan, most HCW infections were from home, not from work.) o Tom's work ing on concept to engage presumably immune COVID-19 survivors (as was done w ith Ebola). • Jeremy Konyndyk {CGD) - "Great idea." o Need to think creatively about how to expand the public health workforce for the coming 18 months, especially for tasks like contact tracing . We 'll need to view CDC and local health dept folks not as boots on the ground but rather as force multipliers - sharing their skills with others and mentoring/managing larger teams to extend their reach. From: Conover, Craig_________ Cb _> _<_ > sent: Sunday, March 22, 2020 5:01 PM To: Kilmarx, Peter (NIH/FI_C:..: )[ ~E:.!: )l ====-=-----::-:-(b - )-:<6>i _.; Stephen Morrison I___ Glass, Roger (NIH/Fie) [E]I CbH6J r>; Charles Holmes CbH6l;Glenn Blumhorst l (b)(6)l; Duchin, Jeff CbH 6)J >; Angela Dunn =======(b~ )(~6)1>; Cindy Burn""e-u•1======' (b ~~:::; (6)] ~ :>__.. -------~~ _ (b)(6) ------------,,-:-= --------- (b)(6)j -------- Subject: Re: Call - follow-up: COVID-19 Response Corps Thanks for all your work on this, Peter ! Re LTCs--attached is a draft document listing all the capab ilities that need to be in place for LTCFsto respond to Covid-19. Develop ing and disseminating guidance aimed at LTCFsis relatively easy--the failures are going to be around implementation . This is one area where assistance wou ld be valuable. cc From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 3:16 PM To: Stephen Morrison Charles Holmes I (b)( > CbH6>;>; Glass, Roger (NIH/FIC) [E] I ----(b) (6)]>; Glenn Blumhorst :.===========------==========,::;;--(b)( 6)]>; Conover, Craig I :.========-~c,"'.:'.-:-" --------- (b)(6); ouch in, Jeff CbH6)]; Angela Dunn (b)(6) J ;,.._...;:.:====-~~----- Cindy Burnett ! (b)(6)j Subject: [External] RE:Call - follow-up: COVID-19 Response Corps (b)(6)j; Thanks all for our call and support for t his concept. Please let me know any critical additions or corrections to these notes . • Jeff Duchin (Seattle) noted multiple possible roles in contact tracing, mitigation with homeless and incarcerated, adverse consequences of social distancing, infection control support, alternat ive care site coordinat ion, lab specimen collection and transport . He shared concerns about infection prevention and thei r PPEshortage. CDChad 40 people deployed, but they departed . Longer deployments (e.g., >90 days) needed to validate onboarding and training effort . He will follow up with more detail on potential roles and numbers. • Angela Dunn (Utah) agreed wit h roles in contact tracing , also st affing a call center, rural out reach and specimen collection. She said Utah was not a current priority for FEMA and CDCwas conducting a transmission study. She shared Jeff's concern about the onboarding effort . • Cindy Burnett (Utah) mentioned the need for social support in rural settings. • Craig Conover (Illinois) added that for them the long -te rm care centers and homeless populations were priority concerns. It would be feasible and helpful to have staff able to collect specimen swabs. • Charles Holmes (Georgetown) made an analogy to community health workers in Zambia and how much can be accomplished and enhanced with tablet-based approaches, workflow apps, and video instructions. • Steve Morrison (CSIS)emphasized the importance of finding an organizationa l home, mentioning potential challenges for both CDCand FEMA. He noted timing of response packages being considered, the hunger for creative ideas, and urgency for this to be brought forward. He noted potential champions, listed with others below. He thinks the Peace Corps connectio n is a compelling factor. • Glen Blumhorst (NPCA) expressed his support and insights on potential champions, e.g., three RPCVin the house. He is going to Capitol Hill tomorrow . • Jody Olsen (Peace Corps) (prior to the call) expressed interest and noted that Peace Corps has no authority to operate in the United States. (The possibility of an Executive Order deta il ing returned volunteers from Peace Corps to state and local aut horities was mentioned by others on the call.) She also noted that Barbara Stewart, Director of CNCS (AmeriCorps and VISTA) has been inviting RPCVsto jo in. Next steps : 1. Revise document (done, attached) to be shared w ith subject matter experts and potential champ ions . (There was not an exact delineat ion of who would share with whom. I will aim to CC: or ask for help w ith some contacts.) 2. Will draft Op-Ed in next 2 days. Action: Share conceptsheet with SMEs and champions avoidingany obvious minefieldsand duplication. Report backuseful feedback. SM Es/champions: • Tom lngelsby • Beth Cameron • Jeremy Konyndyk • Rebecca Katz • • • • Scott Gottl ieb Tom Frieden Scott Dowe ll John Monahan Champions: • Paul Allen Foundation • Dick Durbin • Biden campaign • • • • • Chris Christie Carrie Hessler-Radelet Aaron Williams Pat rick Leahy Chris Van Hollen • • • • • • Dick Durbin Debbi Birx Donna Shalala (RPCV- Iran 1962-64) Joseph P. Kennedy Ill (RPCVDominican Republic 2004-06) John Garamendi (Ethiopia 1966-68) Aumua Amata (PC staf f Northern Mariana Islands 1967-68) Note - GS-7, Step 1 salary is $37,301, Step 5 is $42,273. I've re-set the budget at $100,000 per person to account for benefits, train ing, travel, per diem, management, evaluation, PPE,phones, laptops, etc . From: Kilmarx, Peter (NIH/FIC) [E] Date: Sunday, March 22, 2020 12:35 PM To: Stephen Morrison (b)(6)>; Glass, Roger (NIH/FIC) [El Charles Holmes (b)(6J; Blumhorst, Cathy (NIH/NINR) (b)(6J; [El CbH6)]; Glenn Blumhorst Jody (b)(6) J; Conover, Craig :;::::::=======c::,::;,:c;-:'."'.""""' (b)(~ Olsen, :.=======; (b)(6)>; -----:=====!....:,.. __ ...:_~~ Angela Dunn (b ::;: )~(6) ~1]> -- (b)(6)>; Duchin, Jeff (b)( ---------- Subject: RE: Call: COVID-19 Response Corps Hi all, I'm looking forward to our WebEx meeting in 90 minutes. The concept note (unchanged) is attached. The Web Ex info is below. Here's an updated agenda: 1. 2. 3. a. b. c. d. e. 4. Welcome and introductions Background and proposal Round robin perspectives Public health - WA, IL, UT Peace Corps - Jody Strengthening the concept - all Advocacy - all Implementat ion - all Next steps and way forwa rd -----Origi nal Appointment ----From: Kilmarx, Peter (NIH/F ie) [El Date: Saturday, March 21, 2020 9:29 PM To: Stephen Morrison; Glass, Roger (NIH/FIC) [E]; Charles Holmes; Blumhorst, Cathy (NIH/N INR) (E]; Glenn Blumhorst; (b)(6) Olsen, Jody; Duchin, Jeff; Conover, Craig; Angela Dunn Subject: Call: COVID-19 Response Corps When : Sunday, March 22, 2020 2:00 PM-3:00 PM (UTC-05 :00) Eastern Time (US & Canada). Where: WebEx Please join tomorrow for WebEx discussion of developing a U.S. COVID-19 Response Corps. Concept sheet attached. Agenda : 1. We lcome and introductions 2. Background and proposal 3. Round robin perspectives 4. Discussion 5. 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(b) (4) - If you are a host, go here to view host informat ion. lv1PORTAW NOTICE:Please note that this Webex service ~llows audio and other information sent during the session to be recorded. which rnay be d iscoverable rn a legal matter By Joining this session, you automat1cally consent to such recordings If you do not co11sentto being recorded, discuss your concerns with the host or do not join the session State of Illinois - CONFIDENTIALITY NOTICE: The information contained in this commun ication is confidential , may be attorney-client privileged or attorney work product, may constitute inside information or internal deliberative staff communication, and is intended only for the use of the addressee. Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify the sender immediately by return e-ma il and destroy this communication and all copies thereof, including all attachments. Receipt by an unintended recipient does not wa ive attorney-c lient privilege, attorney work product privilege, or any other exemption from disclosu re . Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director, Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) Charles B. Holmes, MD, MPH Professor of Medicine Faculty Co-Director , Center for Global Health Practice and Impact Georgetown University Medical Center Building D, Suite 120 4000 Reservoir Rd NW, Washington DC 20057 Phone (b) (6) From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 13 Apr 2020 15:25:44 +0000 Corey, Larry FW: perhaps useful in the physical mitigation battle to buy 6 weeks (b)(4 l Larry: I will call yo u about t his to day. This is really im port ant. (b) (4) Thanks, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informatio n. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Eisinger, Robert (NIH/NIAID) [E) (b)(6)> On Behalf Of Fauci, Anthony (NIH/NIAID) [E) Date: Monday , April 13, 2020 7:10 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: perhaps usefu l in the physical mitigation battle to buy 6 weeks ---------- ------ -------- ::;..,..-,= An email below fr om Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immed iate Office of t he Director National Inst itute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( CbH > From: Corey MD, Larry Date: Sunday, April 12, 2020 11:31 PM -------, To: Conrad, Patricia (NIH/NIAID) [E] < ,a-s-r;= Marston, Hilary (NIH/NIAID) [E] (b)(6)>; (b) (6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: perhaps useful in the physical mitigation batt le to buy 6 weeks Here is data from Seattle up to this weekend From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 13 Apr 2020 14:37:16 +0000 Auchincloss, Hugh (NIH/N IA ID) [El RE:Wayne and Catherine Reynolds and Bob Langer/MIT innovations Thanks! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Auchincloss , Hugh (NIH/NIAID) [El (b)(6)> Date: Monday, Apri l 13, 2020 8:12 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: RE: Wayne and Catherine Reynolds and Bob Langer/MIT innovations --------, .....,..,= Possible response below : Dear Wayne, (b) (5) Please give my best to Catherine and take care during these difficult times. Best personal regards, Tony From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 9:27 PM -------- (b)(6)> To: Auchincloss, Hugh (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subject: FW: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Hugh: Please take a look at these 3 ideas. You may have heard of Bob Langer. He is somewhat of an inventive genius with whom we have worked before . I need to get back to Wayne and Catherine and I would like your help in my fashioning a response. Thanks, Tony --------------~= (b)(6) From: WAYNE REYNOLDS Date: Monday, April 6, 2020 2:08 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Grady, Christine {NIH/CC/BEP) ~ [E::-:: ] ;::====== ~ ):::; (b (6) ~ Subject: Wayne and Catherine Reynolds and Bob Langer/MIT innovations Tony, Obviously, you have a few other issues on your daily agenda but, when you have a minute, we wou ld appreciate your thoughts and guidance on three new Bob Langer biotech developments. We have attached three links to recent MIT News art icles. These three innovations at the Langer Lab were originally funded by the Gates Foundation. We thought the last two breakthroughs, in particular, may be applicable to your current work. Thank you again for your continued guidance . Best wishes, Wayne Reynolds Cell : (b)(6) (b)(6) Home: ------ Heat stable micronutrientsfor better nutrition http://news.mit.edu/2019/micro part ides-fight-malnutrit ion -1113 On-patient invisiblevaccinationrecord http://news .mit .edu/2019/storing-vaccine-history-skin-1218 Self- boosting vaccine platform for faster and stronger immune response http://news.mit.edu/2017 /one-vaccine-injection-could-ca rry-many-doses-0914 Fauci, Anthony (NIH/NIAID) [E) Mo n, 13 Apr 2020 13:03:45 +0000 Jenny Fauci From: Date: To: Cc: (b)(6) (b)(6) RE:FW: Google Alert - Fauci AND Tony ORAnthony Subject: (b)( 6) Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Di seases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail ,___,,. __ _, (b)(6) The in ormation in t ,s e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: t Date: k:,-o-n-da_y_, -A-p-ri-11 - 3-,-2-0-20 - 7-:S_S_A_M __ > -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Google Alert - Fauci AND Tony OR Anthony (b)(6) On Sat, Apr 11, 2020 at 1:27 PM Fauci,Anthony (NIH/N IAID) [E)______ _>_<_ > wrote: Cb If you have time, click to link on the bottom: "How Anthony Fauci Became America's Doctor". It is a long article in New York magazine written by Michael Spector a former Washington Post and NY Times writer who has known me for over 30 years. It is the most comprehensive report on me and my career - very insightfu l. Anthony S . Fauc i, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Saturday, Apr il 11, 2020 11 :51 AM To: Fauci, Anthony (NIH/NIAID ) [E] (b)( > Subject: Goog le Alert - Fauci AND Tony OR Anthony ------~~ Google Alerts Fauci AND Tony OR Anthony As-it-happens update• April 11, 2320 WEB Fauci: Virus antibody tests expected next week North Platte Post Dr. Anthony Fauci answers questions during Thursday's Coronavirus Task Force briefing. WASHI NGTON - The top U.S. infectious disease official ... 11 CJ Flaa as irrelevant anthon y fauci The Bulwark Podcast anthony tauci, anti-anti-trumpism, china, coronavirus, covid-19 , donald trump , elections, hydroxychloroquine, masks, navy peter navarro , white house, ... 11 CJ Flaa as irrelevant CBS Evening News with Norah O'Donnell Facebook Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) : "This is not the time to feel that, since we have made such ... 11 CJ Flag as 1rreltwant How Anthony Fauci Became America's Doctor by Michael Specter Longform A profile of the doctor who has run the National Institute of Allergy and Infectious Diseases for 36 years . 11 CJ Flao as irrelevant You have received this email because you have subscribed to Google Alerts . Unsubscribe B!Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 10:16:00 +0000 Nicola Pizzoli RE:COVID 19: Possible main cause of fatalities, it could be not respiratory Thank you, Nicola From: Nico la Pizzoli (b)(6) Se nt : Monday, April 13, 2020 6:07 AM ------~~ -------- To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: COVID 19: Possible main cause of fatalities , it could be not respiratory Good morning Dr Fauci, Ive been follow ing you on COVID brief ings from the White House every night. I trust yo ur experience , professionality and above all your wisdom in these weeks. While I am a mechanical engineer and I run my food company fro living, I have been interested and passionate to the global fight to the Coronavirus. SUGGES TION: Could it be possible that peop le die of pulmonary micro t hrombo sis rather than respiratory issues? If this is the case, this is more a cardiovascular issue than a respiratory, and ventilation or intubation do not count as much as, instead, to give patients some drugs to prevent the t hrombosis , such as ANTI-INFIAMMATORIES.If you ventilate a lung where blood doesn't get there, may be it's useless! In fact 9 out of 10 die . If the problem were cardiovascula r and not respiratory, then it could be a venous microthrombosis and not pneumonia that determines fata lity. And why are thrombi formed? Because there is an inflammation that induces th rombosis through a complex but well-known pathophysiological mechanisms. I know this thesis is right the contrary of some recomm endations that several doctors all over the world (in China first) had made so far: no ibuprofene, no anthibiotics etc etc. But I bel ieve that some researches on the cardiovascular problem induced by inflammation would be worth doing it. An apology for my English. Thank you for your attention, Stay healthy! Kindest regards Nicola Nicola Pizzoli President & CEO PinollSp.A. \'b 1nulillo ~ ord I •..COOSA11.idrie• lloloi;u ----.... ~ From: Date: Fauci, Anthony (NIH/N IAID) [E) Mo n, 13 Apr 2020 02:17:18 +0000 (b)(6) (NIH/NHLBI) [E) Redfield, Robert R. (CDC/OD) RE:Comparison of COVID-19statistics in US vs. China ----- To: Cc: Subject: (b)(6) Thank you for you note. This pandemic has been extremely challeng ing for many countries around the globe including China and the USA. I can only say that I (and I am sure that Bob Redfield feels the same way) prefer to look forward and not to assign blame or fault. There are enough prob lems ahead that we must face together. Best regards, Tony -------- (NIH/NHLBI) [E] Date: Sunday, April 12, 2020 9:51 PM To: Redfield, Robert R. (CDC/OD) From: (b)(6) ----~~ (b) (6) > ------ (b)(6) (b)(6)> Fauci, Anthony (NIH/NIAID) [E) -------- (b)( > Cc: (b)(6) {NIH/NHLBI) [E] Subject: RE:Comparison of COVID-19 statist ics in US vs. China Dear Dr. Redfield and Dr. Fauci, Aft er some hesitation, I decided to write you this message anyway and hope you don't mind. I am concerned about the recent fig ht between the US and WHO because it may adversely impact the current global efforts in controlling the spread of COVID-19. As we all know, US has been leading WHO's efforts for decades and essentially WHO's role is mostly coordinating responses in low- and middle income countries with support from the US and other high income countries. Frankly I was looking for leadership from the US CDCrather than WHO when I was doing (b)(6) . Until COVID-19 is controlled in all countries, t he infection could come back to hit us in this country again. Therefore it is now the worst time to undermine WHO's global coordinating capabilities. What I learned from my former colleagues and friends in (b)(6) where I attended medical school and obtained my MSc in epidemiology might offer some explanation for the differe nces in COVID-19 statistics in US vs. China. Please find attached a couple of articles published by my former colleague, Cb ~ st ___ , of which the 1 attachment is a more updated version . (6) • First, the maximum lockdown in Wuhan that started on January 23 and also in the rest of the entire Hubei province of 59 million peop le during the subsequent 2-3 days, coupled with maximum efforts in early identification, immediate isolation of identified infected individuals and close monitoring of contacts, did work and had to work according to epidemiological principles. China did it by invoking level 1 public health response that was historically reserved for smallpox, plague or cholera, which essentially enabled the entire country to be completely locked down for several weeks. Many vi llages and townships set up checkpoints to refuse anyone to come in or go out; a driver from Hubei had to stay on an inter-provincial highway for 20 days surviving by begging instant noodles from people policing exits; all front doors of residents in a township in Hubei were sealed by local government officials and volunteers to prevent them from getting out of their houses. • Second, there must be under -reporting of COVID-19 cases and deaths because the public health and hospital systems in Wuhan and a few other hardest hit municipalities were overwhelmed for one to two weeks; conceivably many infected individuals were not getting a chance for testing and some of them must have died without being identified as COVID-19. I'd say that this kind of under-reporting is unavoidable, especially in the epicenter of a new pandemic. Actually I suspect that such under-reporting could have happened in this country as well although perhaps to a lesser degree. • Third, there could be a third category of casualties, that is, patients who were suffering from chronic diseases but couldn't get necessary treatments because hospitals were overwhelmed. I read a sad story in social media in which a patient who needed frequent dialysis comm itted suicide by jump ing out of his window. It is highly likely that many such patients died during the lockdown even though I couldn't confirm the specific case or find any statistics. There could be many other collateral damages including socio-psychological effects . Combined, the effect of the maximum lockdown, the under-report ing of COVID-19 cases and COVID- 19 deaths as well as collateral deaths of other causes that were associated with the lockdown could be several times of the reported statistics from China. Here I'd not say that China purposely underreported COVID-19 cases or deaths but rather, China pursued an extreme approach and achieved an extreme result, including severe collateral damages. Of note, Dr. LI Wenliang (the whistleb lower) voiced concern on 12/30/2019 and was criticized for having not followed the legally proper reporting process but nevertheless the WHO China Office was informed on 12/31/2019 of a pneumonia of unknown cause, detected in the city of Wuhan in Hubei province, China (https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen ). We in the US and many other countries pursued different approaches, which are more humane but less effective in terms of blocking transmissions. This is the reality, which needs to be commun icated with and recognized by the public; to make the humane approaches work as effectively as possible, we need everyone's support and cooperation, which cannot be achieved by blaming China or WHO. The public has to understand that we are in a pandemic, which means that tens of millions are supposed to be infected and millions are supposed to die from it, unless we take necessary actions to block the transmission and to take good care of the infected. Finally, I'd like to say a few words for public health colleagues in China. In my personal view, to be fair, they have done their best to inform the global public health community of the COVID-19 outbreak in Wuhan, China by briefing WHO and many count ries as soon as they identified COVID-19 (12/31/2019 1/3/2020) ; they shared the genetic sequence of the virus on 1/ 12/2020; and the numbe r of scientific and medical publications in English shortly afterwards was unprecedented . I did a brief search and identified the following: A Novel Coronavirus from Pat ients with Pneumonia in China, 2019 (1/24/2020) https://www.nejm.org/doi/full/10.1056/NEJMoa2001017 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person -to -person transmission : a study of a family cluster (1/24/2020) https://www.sciencedirect.com/science/artic1e/pii/S0140673620301549?via%3Dihub Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (1/24/2020) https ://www.thelancet.com/journa ls/lancet/ article/Pl 1S0140-6736(20)30183-5/ f ulltext Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-l nfected Pneumonia (1/29/2020) https ://www.nejm.org/ doi/fu 11/10.1056/NEJMoa2001316 Genomic characterisation and epidemiology of 2019 novel coronavirus: implicat ions for virus origins and receptor binding (1/30/2020) https://www.thelancet.com/article/S0140-6736(20)30251-8/fulltext A new coronavirus associated with human respiratory disease in China (2/3/2020) https://www.nature.com/artic1es/s41586-020-2008-3 Early estimation of the case fatality rate of COVID-19 in main land China: a data-driven analysis (2/12/2020) http:ljatm.amegroups.com/article/view/36613/html Characteristics of and Important Lessons From the Coronavi rus Disease 2019 (COVID-19) Outbreak in China (2/24/2020) https://jamanetwork.com/journals/ jama/fulla rticle/2 762130 It is my hope that US and China could join fo rces to help low- and middle-income countries to control the pandemic so that it will not come back and hit us again after the current wave in this country is controlled. I am not sending th is message through the official channel because this is not part of my official duty and is purely my personal opinion. Sincerely, (b)(6) Doing human subjects research? New policies will impact you! Learn more . Looking for NHLBI Clinical Trial Funding Opportunities? Learn more here. From: Date: To: Subject: Attachme nts: Fauci, Anthony (NIH/NIAID) [El Mon, 13 Apr 2020 01:37:27 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: [COVID-19 Pneumon ia] Official Letter from lmmuneMed Inc. Off icial Letter from lmmuneMed-NIAID.pdf Please take a look at this and respond. From: Sungpill Park Sen t: Sunday, April 12, 2020 9:31 PM To: Fauci, Anthony {NIH/NIAID) (E]-------=(b"""" )(=6) Subject: (COVID-19 Pneumonia] Official Letter from lmmuneMed Inc. Dear Dr. Anthony S. Fauci, My name 1s Sungpill Park, and I'm a representative of lmmuneMed, Inc. located 1n Korea. We specialize in diagnos ing and t reating the infectious diseases. Our company's hzVSF(humanized Virus Suppressing Factor) v13 is under curable usage for COVID-19 pneumonia, utiliz ing Korea's compassionate use system for patients who do not have an alternative treatment. I am writing with a strong conviction that t he partnership between the National Institute of Allergy and Infectious Diseases and lmmuneMed , Inc. wil l bri ng the decrease of death rate for COVID-19 pneumon ia. I ask you humbly to please spend a minute of your busy time reading the attached letter from our CEO, Dr. Yoon-Won Kim, to find out more about the hzVSF treatment and how we can wor k together to cure COVID-19 pneumon ia pat ients. With Regards, Sungpill Park, MBA Vice President, Global Business Development lmmuneMed, C: ------ Inc. (b)(6) I E: sppark@ immunemed.co.kr w: www.immunemed.eo.kr/en/ Notice : The above message (and any attachment) is intended solely for the named address and may contain information that is privileged, confidential or otherwise protected under applicable law. Any unauthorized dissemination, distribution, copying or use of the information contained in this communication is strictly prohibited If you have received this communication in error, please notify the sender by email and erase this communication immediately. From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:20:22 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 participation Let us discuss. From: Dzau, Victor J. Date: Thursday, April 9, 2020 11:01 AM To: Mun , Jenny ; Fauci, Anthony {NIH/NIAID) [E) (b)(6l; >; Hannon, Emma ; Conrad, Patr icia (b)(6) 'ben.tinke r@cnn .com' ; 'Amanda .Sealy@cnn.com' ; 'Neel.Khairzada@turner.com' ; 'Tia.M iller@turner.com' ; (b)(6) Subject: RE:NAS Annual Meeting Session on COVID-19 -- Information regarding your Saturday April 25 pa rtici pat ion Dear a ll, Thank you for agreeing to participate in a special late breaking session on the COVID-19 pandemic at the NAS annual meeting. Knowing how busy you are, I am sending this email in lieu of a call to prepare for the session . As you know, this is a 90 minute session which aims to provide our audience with deeper insights into the latest developments in the COVID-19 response. I plan to hold an engaging discu ssion that covers the whole experience on dealing with this pandemic - from US to international, to preparedness and response, the biology of the virus, the state of diagnostic, treatment and vaccine development, and the importance of communica6on. l will begin the session by providing brief (~3 min) opening remarks describing the circumstances of the pandemic . Then, I will introduce the panelists and you will each have 7 minutes to provide remarks. You may use a limited numbe r of slides for illustration. I hope that each panelist will provide their own perspective and speak to the issues proposed below. • Jeremy Farrar will discuss the global response to the pandemic, drawing from his experience as a global leader, the chair of the Scientific Advisory Group for the WHO's R&D Blueprint and as a member of the Global Preparedness Monitoring Board. • Tony Fauci will discuss the US pandemic and provide his perspective as a member of the White House Coronavirus Task Force addressing the 2019- 20 coronavirus pandemic. • George Gao will discuss China's response to the pandemic and lessons learned for the rest of the globe . • Susan Weiss will discuss the viral characteristics of SARS COV2 , insights into its patbobiology, immunity and development of a pan-CoV antiviral. • Richard Hatchett will discuss the development of new vaccines and treatments against COVID-19. • Sanjay Gupta will comment on the health system response to the pandemic and challenges re lated to communication and pub lic engagement in responding to COVID -19. Following remarks from each panelist, we will have a moderated discussion amongst ourselves l will ask you a set of questions (15 mins) and then we wil! take questions from the web (25 mins). To prepare me to be your moderator, please send me any questions you would like me to ask you. For those of you who would like to have a prep call, please let me know and I will set it up. Best, Victor From: Mun , Jenny Date: Wednesday, April 8, 2020 10:56 AM 'ben .tinker@cnn .com' ; 'Amanda.Sea ly@cnn.com' ; 'Nee l.Khairzada@turner.com' ; 'Tia.M iller@turner.com' Subject: NAS Annual Meeting Session on COVID-19 -- Information regarding you r Saturday April 25 participation Dear Speakers: I am the logistical contact for the COVID-19 session that w ill be held as part of the Annual Meeting (online) program on Saturday, April 25 at 2:00 pm EDT. Thank you for agreeing to participate in this session. To help you with your planning, I have provided additional details below . Please note that the session w ill be live webcast and the general public will also be able to watch the session. Video from the session will also be uploaded on the NAS YouTube channel (https://www.youtube.com/user/theNASciences ) after the meeting . We will need to obtain signed speaker release forms for your participation in this session. I have attached the speaker release form for your rev iew and subm ission . Please return the signed speaker release form by Monday , April 13. Session speakers are asked to connect 30 minutes prior to the session start time (by Saturday, April 25 at 1:30 pm EDT)to allow the technical staff to check connections and prepare for the session. Details on how to connect will be sent before the meeting. We w ill list you in our promotional materials as noted below. If this is incorrect, please let me know . Anthony 5. Fauci, Director, National Institute of Allergy and Infectious Diseases Jeremy Farrar, Director, We llcome Trust George F. Gao, Director-General, Chinese Center for Disease Control & Prevention Sanjay Gupta, Chief Medical Correspondent, CNN Richard J. Hatchett, CEO,Coalition for Epidemic Preparedness Innovations Susan R. Weiss, Professor of Microb iology, Perelman School of Medicine, University of Pennsylvania Since many of us have moved to remote work environments, you may already be proficient w ith Zoom and other online meeting/collaboration applications . I am attaching a 'speaker guidelines' file in case you have any questions on how best to prepare for and stage your remote talk. We have technical staff available to help you become familiar with Zoom and its settings - such as "sharing your screen" (if you have slide presenta tions that need to be shown during your talk) . We can arrange for a training session this week or next week . If you would like to schedule a session, please let me know as soon as possible. Dr. Dzau's office will be in touch regarding the agenda for this session. If you have any othe r questions, please let me know . Regards, Jenny ******************************** Jenny Mun Membership Director National Academy of Sciences jmun@nas.edu (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 23:00:07 +0000 Seth Berkley (Private) RE:Checking in Thanks, Seth! --------- From: Seth Berkley (Private) Date: Saturday, March 28, 2020 3:48 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Checking in ------~= (b)( > Hi Tony: You are doing an amazing job during these very diffic ult t imes! Doing everything we can here to support WHO to work on global acceleration of SARS-CoV-2vaccine development as well as support our 73 poorest countries for COVID-19 preparation and hopefully keeping routine vaccine coverage as high as possible. We are prepared to ultimately roll out a vaccine when one is ready. No need to respond, but wanted to give you a friendly shout-out. We are all thinking of you! Best, Seth The private email account of Dr Seth Berkley Chief Exec utiv e Officer Gavi, the Vaccine Alliance Tel: Skype (b)(6) -------@GaviSeth Twitter (b)( , The Global Health Campus, Chemin du Pom mier 40, 1218Le Grand-Saconnex Swi tzerland Tel: CbH6) Web: http: //www .gavi.org With the suppo rt of donors and pa1tners, Gav i, the Vacc ine A lliance is working to immunise an additional 300 million children betwe en 2016 and 2020, preventing a further 5-6 million deat hs. Join us and help to reach every child. Visit www. gavi.org . sign up for the Gavi newsletter and follow us on Facebook and Twitter. NOTIC E : This emai l, includin g any attachments to it, may be confide nt ial and does not create any binding contract on behalf of Gavi or its partn ers . If this ema il was sent to you in error, please notify the sender immediately by rep ly e-m ail, and please do not use , distribute , retain, print or copy the e-mai l or any attachment. From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 22:58:02 +0000 Herbert Mathewson RE:PERSONAL:My April 1 blog on Tony Fauci, CUMC ----- (b)(6) Hub: Many thanks for your kind note. Warm regards, Tony From: Herbert Mathewson (b)(6) Date: Saturday, March 28, 2020 1:57 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: PERSONAL:My April 1 blog on Tony Fauci, CUMC ------~~ ----- (b)(6) Tony, I have been writ ing an annual April 1 column for 30 years, first in my monthly newsletter at Cape Cod Hospital and now as my biweek ly blog of medical fun facts at www. hubslist.org. This is a heads up before publication of this year's Apr il lblog about you and Biden. I suspect that most of our classmates are, like me, boasting a bit about having you as a classmate. Your honesty and "truthiness" is most appreciated and greatly valued by us amidst the leadership chaos. Your success at "walking the line" is extraordinary . Enjoy. Hub • Home • Hub's List of Medical Fun Facts Vol. 230 April 1, 2020 Biden Picks His Running Mate Press Conference For mer Vice President Joe Biden April 1, 2020 (Official Transc ript) BIDEN : Good morning everyone. I am glad to see all you reporters sitting 6 feet from each other . I know it is burdensome, er, what?, ... but we must work together to defeat this awful Zika . . . Rebola ... the flu . . . I mean, you know, the Coroner virus . Speaking of the current virus crisis . . . boy that has a nice ring to it, doesn't it? ... it almost rhymes . .. I would like to announce my pick of a running mate; Dr . Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease of NIH since 1984 .. . almost twenty .. . er . . . many years ago . Now before I start to answer your quest ions, let me give you some reasons for my choice . Number 1: Dr . Fauci is smarter than I am, but I am ta ller and younger than he is . Number 2: He is very experienced. came to Washington ... He has worked with many President ial administrat ions since he in the 1980's as I remember . He told Ronald Reagan about the AIDS epidemic, advised two Bushs . . . one of them gave him the Presidential Meda l of Freedom ... by the way, Ben Carson got his medal during that same ceremony, . . . where was I? Oh, yeh . . .two Clintons .. . yes two, remember Hilary's Health Care Plan? . .. and, of course, Obama or two. Number 3: He gives very good TV interviews , even on Fox News with Sean Hannity trying to mislead the viewers. Number 4: His medical training has given him that special skill that all physicians must have to succeed - "Always sound right, and if you don't know an answer, make one up." But he is like one of my famous namesakes on Dragnet . . . Sergeant Joe Friday . .. "Just the facts, Ma'am." Now I'll take your questions. [Sounds of shouting , general loud babbling , a baby crying , a chair falls over] REPORTER : " Mr. Biden have you moved away from your promise to pick a female running mate?" BIDEN : Did I say that? When was that? ... Oh, it was during one of those debates? ... I wouldn't call it a promise. It was a statement from which I am now socially distancing myself, and that makes it a very timely question. hair in weeks ... . .. This social distancing is for the pits. I haven't smelled a good head of for the record, my test was negative ... be heard in my administration and I will ensure that women's voices will by appointing several to my cabinet. Elizabeth Warren naturally will be Secretary of the Treasury. Kamala Harris as an experienced prosecutor would be an excellent head of the Department of Justice . .. I think she is Latino too, isn't she? ... I am not sure about Senator Amy Kolbuchuck from Minnesota and she has great hair, but Marianne Williamson, ... the physic healer ... could serve as Chief of the Alternate Universe remember, . . .excuse me, Alternate Therapies within HHS. Adding Senator Gillibrand to the cabinet would weigh the group too heavily towards New York, since Dr. Fauci is from Brooklyn. I will, of course, appoint Tulsi Gabbard as Ambassador to America Samoa. REPORTER : "Do you have any concerns about any regrettable incidents in Dr. Fauci's past?" BIDEN : Not really. My staff has vetted him very thoroughly. The only whiff of scandal we found was his medical school yearbook picture where he was being lifted by two of his taller classmates so as to appear as even taller than they. None of them were in black face. Also some people may have difficulty knowing how to pronounce his name correctly. It is pronounced as "Fow-ch i" with the soft "c" sound common to many Italian names, . . . and as the Senator from Nevada I wish to say that I have many ItalianAmerican friends who are hard-work ing, decent citizens, but I must excuse myself from this Corleone hearing for another important committee meeting ... again? ... oh, sorry ... was I channeling the Godfather a great movie. There is another small concern, since he is from New York City and his name ends in a vowel people may think he is associated with Rudy Giuliani .... but we know that he is taller than Mike. We have completely debunked the New Yorker Magazine stories that Dr. Fauci has recommended internal alcohol to kill the coronavirus since external alcohol really doesn't work. In fact, he only recommended it as an antidote to the daily briefings of the White House Coronavirus Task Force. Dr. Fauci also noted that internal alcohol effects may be briefer t han the briefings, so viewers may repeat a dose PRN (as necessary). REPORTER : " Is it true that as noted in your background Press Release just handed out that Dr. Fauci was born on Christmas Eve, and are you concerned about any back lash from Trump supporters who regard Trump as the Second Coming." BIDEN: Dr. Fauci is an American . Even though he was born in Brooklyn, there is no question about his citizenship eligibility for this office. I think that a resurgence of the Birther Movement which was so viscously directed at my close friend and mentor, Barrack Obama, . . . there I final ly got his name out there ... would be very unfortunate. Next question. REPORTER : "Has Dr. Fauci made any significant contributions in fields other than virology and infectious diseases." BIDEN : Well let me tell you a down-to-earth, contributions. fascinating story of one of his most significant It will be a short one, I promise. Since the Coroner virus pandemic has taken over all the headlines, editorial pages, social media memes, political cartoons, TV shows, graphic artist shops, and a lot of other things swamping articles about the Opioid Deaths epidemic, Dr. Fauci has developed a new attention -getting graphic to replace the familiar 1-10 faces of pain levels; Pandemic Panic levels. the 1-4 faces of 1 2 REPORTER: "But face 4 is the same 4 as face 2. Isn't that a confusing message ." BIDEN : Exactly "Thank you Mr. Biden, and Happy April Fools Day. " PS: (b)(6) yearbook picture that won't be in the blog. (b)(6) This entry was posted on Saturday, March 28th, 2020 at 10:01 AM and is filed under coronavirus, current events, humor, Infectious Disease. politics. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site. Edit this entry. Post navigati • RECENTISSUES o Vol. 229 March 15 2020 Beware the Ides of March o Vol . 228 March 1. 2020 Phvsician Speeders, Roundup Off One Hook, and Don't Shoot the Cows o Vol . 227 February 15. 2020 Milk is NOT Good For You?! o Vol . 226 February 1, 2020 Current Controversies . .. other than Impeach ment . • • YOU ARE FOLLOWING THIS BLOG You are fol lowi ng this blog, along with 216 other amazing people ( mana ge). Blog at WordPress.com. Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:38:10 +0000 Holdren, John P. RE:Antiviral SNA w hit e paper From: Date: To: Subject: Thanks,John. ------------ From: Holdren, John P. Date: Wednesday, March 25, 2020 4:27 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] ======= -------~~ (b)(6) (b)(6) (b ~~~(6) ~ Subject: FW: Antiviral SNA white pape r Dear TonyI know you are overwhelmed, but the attached whitepaper on a vaccine-development idea migh t be worth a look . You may member Chad lv1irkin as a member of the Obama PCASTwhose extraordinary contributions across a range of science and engineer ing issues have landed him in the NAS, NAE, and NAM, among other distinctions - a verr smart guy. Aside from that, thank you for your courageous truth-telling in the incredibly demanding situation in which we find ourselves. My best, John John P. Holdren Teresa and John Heinz Professor of Environmental Policy John F. Kennedy School of Government Professor of Environmental Science and Policy Department of Earth and Planetary Sciences Affiliated Professor John A. Paulson School of Engineering and Applied Science HARVARDUNIVERSITY Assistant: --------------------------- From: Chad A Mirkin (b)(6) Date: Wednesday, March 25, 2020 3:57 PM To: Holdren, John P. Cb)~ > Cc: Robert A Lamb CbH6);Andrew Lee Subject: Antivira l SNA white paper (b)(6) ------------- (b)(6) (b) (4) Thanks and best regards, Chad Vr. ~uci rc:Jc p,·<:./A ' I\ T RI}// W,stN le. 1 SARS \Jest MCl2.5 N,le s ,..lfpo; 5.....11 '1 C:&ol« \},) (0(0(10.\11 cf,olq (\J!, fT~An --- 0 u a, ,Jq...,f'O,< f:bol, ,_ folio H Hcf..}i~,s B g/) Ht•ro zko. M('o.$1<} Mo le> (b)( 6) \J f s T z ;kc. t07:/Jtj w Cheers, John T. Brooks, MD Chief M edical Offi cer, CDC COVID-19 Respon se Email (b)(6) Apologies for error s in dictat e. l 1) Me~lc:.$ T -I f<.ot t'S C.o01"1~ I 0 E: s I 11 flvt1W1HIIIJ (Cf OIOVtN,S Ml/l.. S 5 w Mo~k-)( A NQc1t1.al k s (IVC•""" my messages that may be due to my need to From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:18:05 +0000 John Dirks RE:Great leadership John: Thanks for the note, Much appreciated. Best, Tony From: John Dirks (b)(6) Date: Wednesday, March 18, 2020 5:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Great leadership -------- CbH6)> Tony, I admire the tremendous leadership and expertise you are provid ing during this COVID-19 crisis-I know it not easy-but your advice is so credible and listened to, Best John Dirks From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:17:08 +0000 Lewis M Drusin RE:Coronavirus Thanks, Lew -----Original Message ----From: Lewis M Dmsin _______ """ (b'"" )...,. (6) => Date: Wednesday, March 18, 2020 11:24 AM To: Fauci , Anthony (NIH/NIAID) [E)._ ______ Subject: Coronavirn s -------~~ (b _ )_ (_. 6) Tony When people ask me about coronavi rus, f j ust tel I them to listen to you. Your ca lm, steadfast exp lanation of tbe science is a major factor in the public trusting government to resolve this incredible publ ic health cris is. Hope you are do ing well. Best wishes as alway s Lew From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:21:16 +0000 EI-Gabalawy, Nadia (PHAC/ASPC) To: (b)(6) Cc: Subject: RE: Hello from Canada! Nadia: Many thanks for your kind note. Best regards, Tony From: EI-Gabalawy, Nadia (PHAC/ASPC) Date: Monday, March 30, 2020 2:48 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Hello from Canada! ------------ (b)(6) --------=-=--:-= --------- (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. Hani EI-Gabalawy, did a research sabbatical at NIH ________________________ _ Amazing work that you're doing. I've been following your discussions and scientific innovat ion regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Network Secretariat to support the Emergency Operations Centre at the National Microbiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we' re on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I' m thrilled to see you advising the public. There is no better person to do the job. Kindest regards, Nad ia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Int elligence Public Health Agency of Canada/Government of Canada (b)(6) (b)(6) Chef d'equipe, Services de soutien, Reseaucanadien de renseignements sur la sante publique Agence de la sante publique du Canada/ Gouvernement du Canada (b)(6) (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:19:01 +0000 Anderson, Jennifer (NIH/NIAID) [E] Lane, Cliff (NIH/NIAID) [E];Clifton, Dawn (NIH/N IAID) IE] RE: LIR Requests for DIR Supplemental Funding (non-COVID related) - PLEASE To: Cc: Subjec t : REVIEW Looks fine. ---------= From: Anderson, Jennifer (NIH/NIA ID) [E] Date: Monday, March 30, 2020 9:38 PM To: Fauci, Anthony (NIH/NIAID) (E]------~ Cc: lane, Cliff (NIH/NIAID) [E)______ (b)( (b)(6)> ,..;...;:...;;.!:====~~~~ Cb _H_ ; Clifton, Dawn (NIH/NIAID) [E] (b)(6)> Subject: LIR Requests for DIR Supplemental Funding (non -COVID related) - PLEASEREVIEW Hi Dr. Fauci, Please review the attached requests for DIR Supplemental Funding on behalf of LIR investigators. I have further summarized the requests in the table below . I took the liberty to provide a suggested ranking based on funding need . Dr. Lane has reviewed the requests and agrees with the rankings as well. (b)(5) Sincerely, Jennifer Cost Pl Supplement Description Priority Order for LAB (b) (5) (b)(5) Jennifer M. Anderson , PhD Deputy Branch Chief 1AMB/OAS/N IAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Maryland 20892 Office Phone : Cb)(6) NIH Cell: (b)(6) PersonalCell: (b)(6) FAX:301-402-4122 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 20:18:33 +0000 Brian Kelsall RE:What can be done? Thanks, Brian. That recommendation is in the works. From: Brian Kelsall (b)(6). Se nt: Monday, March 30, 2020 10:17 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Fwd: What can be done? -------~~ --------- (b)(6) Dear Tony, I'm lucky to have thoughtful neighbors . Please see the email that I received from Sue Edwards. Because of the likelihood that there are so many asymptomatic cases, isn't it time to recommend everyone where a mask of some kind? Not N95 masks or even surgical masks that should be reserved for first responders and hospital staff, but some face covering? Best, Brian Sent from my iPhone Begin forwarded message: From: Sue Edwards (bH > Date: March 30, 2020 at 1:15:06 PM EDT To: Brian Kelsall (b)(6) Subject: What can be don e? Why can't the CDC make a public service announcement that everyone should be wear ing some kind of mask @ in public? It doesn't have to be N95 or even surgical though that wou ld be ideal (as is done in every Asian country) given that the virus is actually aerosolized (several studies confirm this ) and that it can be spread by asymptomatic carriers (which account for possibly more than half of the positive cases - we w ill never know) it seems obvious that food markets are no different from hospitals and in many cases worse since at least in hospitals people are wearing some protective equipment ... just say wear a cotton mask, a scarf, a bandanna , a DIV paper towel mask .. whatever- but no one should be going to a market without one and absolutely no one working in a store or stocking supplies or delivering food, packages, mail etc should be allowed to work w ithout something covering the face- th is includes pharmacists as well, obviously D wtf ls w rong with this country? What use are gloves? When the offending particles are escaping our faces and floating around for several hours, landing on everything around us... the only place it shouldn't be as critical is outdoors in the sunshine where UV light should deactivate viruses fairly quickly ... Sue Hope you are all well - and can give me some hope that this message get through the thick skulls of the so called experts ... even during the 1918 flu epidemic, everyone wore some facial covering when out in public places - what is going on? EVERYASIAN country is employing this approach with much greater success at slowing the rate of transmission - even India! https ://www.nytimes.com/202 0/03/2 7/hea Ith/ us-coronavir u s-face-masks.htm I https://medium.com/better-humans/a orifice-80c2f3f167be Sent from my iPhone -pract ical-guide-t o-covid -conta inment-orifice-by- From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 20 :07:20 +0000 Harold Slavkin Collins, Francis (NIH/OD) [El RE: reaching out t hinking of you Hal: Thanks fo r your note. These divergent phenotypes are truly puzzling. I have copied Francis on this e-mail in case he has any additiona l though ts. Best regards, Tony --------- (b)(6)> From: Harold Slavkin Date: Thursday, April 2, 2020 4:04 PM To: Fauci, Anthony (NIH/ NIAID) [E] -------= (b"'"" )( =6)•> Subject: Fwd : reaching out thinking of you Begin forwarded message: ----- (b)(6) F rom : "Harold C. Slavkin" Subject: reac hin g out thinking of you Date: April 2, 2020 at 11:39:40 AM PDT To: Cb)C6) Cc: "Somerman, Ma1tha (NJH/NTDCR)[E]" -------- (b)(6) Hi Toni, You continue to be "the role model" for leader s in biomed ical research these many decades. I am so proud of your effort s during the se remarkable tim es in history . Thank you! !! I cherish those 5 years {19952000) that I served as Director of NIDR (that became NIDCR) wh en we were able t o co-sponsor effort s to uti lize saliva as an informative fluid for HIV detect ion . For me that was an invaluable opportunity to be part of Harold Varmus' leadership team and to continue my research within NIAMS. I was inspired by your public comments a few nights ago on CNN regarding your observations of significant variance in the pathogenesis or phenotypes noted for subsets of critically ill patients with COVID-19 on ventilators in ICU. I was immediately reminded of David Feinberg (CEOof UCLA Health Sciences, more recently 5 years at Geisingers, and currently CEOof Google Health Companies) who used genotyping for populations around Lancaster PA and discovered about 3-4% with undiagnosed genetic diseases that translated into reduced costs of hospitalization, treatments, etc. Kaiser-Permanente Northern California, and many other systems, have also used this approach since sequencing has become cost effective . Perhaps a select sample of people who require ICU, and another that require ventilator, might inform the genotype of the most susceptible people and might also inform a target to use to discover what exist ing drug or therapy could be mobilized. Through your position, might there already be a large data set of whole genome sequences (e.g. military) that could be rapidly explored using bioinformatics? As you may recall , my personal research activities have focused on craniofacial diseases and disorders. For example, Osteogenesis Imperfects (0.1.) presents cardiopulmonary disorders in addition to bone and tooth disorders. Since penetrance varies, cases of rare cond itions can illuminate "hidden" SNP abnormalities in key gene clusters (e.g. MHC gene clusters, etc.). Considering lung disorders as you mentioned in your comments about pathogenesis, already known gene mutations that present several major phenotypes including pulmonary diseases could become very useful. Perhaps Francis and others at the NIH could create a trans-NIH approach that is enabled to visit this pandemic from the perspective of human phenotype variance discovered via genomics? I asked Martha Somerman to explore the talents available at NIDCR (and beyond) related to connective tissue genetic diseases that associate with Types 1 and 111 collagens, elastics, and hyaluronic acid glycoproteins AND lung tissue fibrosis, etc . She may also reach out to you. Meanwhile, thank you for your untiring efforts to use science to inform health policy. Of course, let me know if I can be of any use to you . Always, Hal From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:42:21 +0000 Susan Corrigan RE:Coronavirus Susan: Thank for the note. I hope that all is well with you. Best regards, Tony From: Susan Corrigan (b)(6);,, sent: Wednesday, Apr il 1, 2020 10:29 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """ (b..,.,. )(=6):> Subject: Coronavirus Dear Dr. Fauci, I have seen quite a bit of you on television. I live in Miami now. South Florida is the epicenter of the coronavirus. I wish Governor Desantis would shut down the state of Florida. Thank you from (b)(6) Susan Corrigan From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 19:41:04 +0000 Nader, Ralph RE:COVID-19 Question Ralph: I am so sorry that I took so long to get back to you. I receive over 1000 e-mails per day and even with staff screening, I do not see them for days. There is still an issue/prob lem with serologic tests in that they need to be va lidated as being sensitive and specific. Many tests that have been used t hus far are not accurate and ARE M ISLEADING. The UK bought millions of these from China and found that they were inadequate. The FDA is in the process of validating ce rtain tests this week and if they pass, then we can expect to have tests w ithin the next few weeks to do the things that you have suggested. Best regards, Tony From: Nader, Ralph (b)(6) Date: Wednesday, April 1, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: COVID-19 Question ------~~ -------- (b)( > Dear Dr Fauci, I hope this email finds you wel l. Thank you for everyth ing you are doing for our country in these difficult times. I realize your time is extremely valuable - especially dur ing these times. I have one question - if you can help me answering it. Why are serologic tests not made abundantly available during these times? This will help in so many ways: - Can it be used to triage healthcare workers? Naturally "vaccinated" healthcare workers may be bet ter triaged to be on the front lines fo r example, taking care of COVID-19 patients. {In times of limited PPE, documentation of natural immunity is probably one of the best PPE's out there) -Another major use for it: People can be asked to remain home, until they have documentation of natural immunization . Serologic tests are very cheap, can be mailed, and done at home. Immunized individuals can carry the test as "proof" of immunity - and may be able to go back to work etc. It is just a thought. It may be a very candid question that I am asking. But while we are waiting for a vaccine (and this will take several months), some people may be able to benefit from a very cheap test (that can be done at home) to short-circuit that waiting time. Thank you for everything you are doing to our country, You are such an inpiration to us all. I wish you all the best. Thank you. Ralph Ralph Nader, MD Renal Fellow - Boston Medical Center Instructor of Medicine - Boston University School of Medicine Email -------- Phone: (b)( ----- (b)(6) Pager: (b) (6) This electronic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediately as use of this information is strictly prohibited. From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [El Sun, 12 Apr 2020 19:29:52 +0000 Billet, Courtney (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [E);Folkers , Greg (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIA ID) [E) Subject: RE: documentary interview request: PBS+ Topspin Productions Let us discuss this tomorrow before we do anything. No one has any "exclusives" on anything about me. From: Billet, Courtney (NIH/NIAID) [E] (b)(6)> Date: Sunday, April 12, 2020 3:27 PM To: Fauci, Anthony (NIH/NIAID) [El ~======::---:'!..-~ Cc: Conrad, Patricia (NIH/NIAID) [El Cb)( '>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; Routh, Jenn ifer (NIH/NIAID) [E] CbH >; Stover, Kathy (b)(6)> (NIH/NIAID) [E] Subject: RE: documentary interview request : PBS+ Topspin Productions -------- (b)(5) (b)( '> From: Fauci, Anthony (NIH/NIAID) [El Date: Sunday, April 12, 2020 3:01 PM -----~~ To: Billet, Courtney (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E]=======~ (b)(6)> (b ")-:-= "'C; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Routh , Jennife r (NIH/NIAID) [E] (b)( ; Stover, Kathy (b)(6)> -------- -------- (NIH/NIAID) [E] Subject: RE: documentary interview request: PBS+ Topspin Productions (b)(S) (b)(S Happy to discuss. ______ From: Billet, Courtney (NIH/NIAID) [E] Date: Sunday, April 12, 2020 2:55 PM To: Fauci, Anthony (NIH/NIAID) [El _____ Cc: Conrad, Patricia (NIH/NIAID) [El (b)_.~ > __,.., (b)..., (6) "" > CbH6J>; Folkers, Greg (NIH/NIAID) [El (b)(6)>; (NIH/NI A ID) [E)______ ----------- Routh, Jenn ifer (NIH/NIAID) [E) (b_H _6)> (b)( ; Stover, Kathy Subject: ASF: documentary interview request: PBS+ Topspin Productions We have received a request from the PBSprogram "American Masters" and Topspin Productions to do a documentary about you. Their near-term ask is one or two brief video-l ink phone interviews during the next few months. After the coronavirus pandemic has subsided, they would like to do "a proper sitdown in which you could tell us the stories that speak to the key moments in your remarkable career." On the face of it, this might seem to overlap with the Tobias/Hoffman project, but in the end I think they'd be quite different products. Please let me know if you'd like us to seek clearance to proceed. On Apr 7, 2020, at 9:26 AM, Lia Carney wrote: Hi Laura, Nice to speak yesterday. See below for formal reque st and informat ion about the series. Jf you wouldn ' t mind confirming receipt of th is email, I can make sure to let me partners in this project know it is in the correct hands . Stay safe and thank you . Dear Dr. Fauci, To re-introd uce myself, I am Lia Dosik Carney , (b)(6) and an executive producer in Los Angele s. As you'll remember, we filmed w ith you last summer as a major participant in a documentary we were producing centered around infect ious disease. Than k you again for parti cipati ng and taking the time . It was great to hear about your extraordinary career as well as a few interesting stories abou t (b) (6) Obviously even ts ha ve taken over all of our lives . Like everyone else in this country, I am very grate ful for your honest and steadfast leaders hip as we navigate our new reality. During this time , we 've been rethinking how we want to proceed with our docume ntary and have come to reali ze focusing on you, your experi ences over the deca des, how you hav e met every challenge presented to you, would give all of us a roadmap for the future. To tha t end we are now in partn ership wi th AMERICAN MASTERS , PBS ' flagship series that profiles and hon ors outstanding Americans. To gethe r we wo uld like to produce a comprehen sive look at your life, your experiences and your ins ights into how to deal with the recurring di seases that conti nue to plague our lives. I have included below an introductory email from American Masters Executive Produce r, Michael Kantor , which will give you a broader sense of that exceptional PBS series and the extraordinary work they produce. We all lrnow how limited your time is now - and all of us are so appreciative of what you are doing. We re:spectfu lly hope you will allow u:s to chronicle your life in medicine. We know that as we emerge from this late st crisi s - understanding how you were able to deal with earlier plagues (HIV-Aids for instance) will - we hope understanding of the challeng es all of us will continue to face. give all of us a better Appreciate your consideration. With respect, Lia Dear Dr. Fauci, My name is M ichael Kantor and I am the Executi ve Producer of the PBSAMERICAN MASTERSseries. I believe you know (b)(6) I am writing today to see if you would allow us to make a film on your life and career. We would require very little of your precious time right now, perhaps one or two very brief video-l ink phone interviews over the next few months, just as you have appeared on Trevor Noah's The Daily Show and spoken with basketball star Steph Curry. Later this year, after the current crisis has subsided, we would find time in your busy schedule for a proper sit-down in which you could tell us the stories that speak to the key moments in your remarkable career. I am excited to work with Lia Carney and Topspin Productions on this project, because it has been important to me to expand the roster of AMERICAN MASTERS films to include scient ists. Over its 33 year history , our series has profiled artists such as Leonard Bernstein, Maya Angelou and Raul Julia, athletes including Billie Jean King and Ted Williams, and now we are presenting the stories of James Watson and Oliver Sacks in our pantheon of great films. Our series is dedicated to telling biographies with the utmost care, and for that reason we have been honored with awards like the Emmy, the Peabody, the Grammy and even an Oscar. We would be honored to have you join us in our public television effort to educate Americans about the domestic and global health issuesthat have been the focus of your career . This letter is brief because we respect your time, but we sincerely hope that you will join us in creating a documentary of distinction for a broad and diverse national audience . Sincerely yours, Michael Kantor Michael Kantor Executive Producer American Ma sters Thirteen IWNET 825 Eighth Avenue New York, NY 10019-7435 212-560 -6975 (office) American Masters website Facebook !Twitter I Tumblr From: Fauci, Anthony (NIH/NIAID) [El Date: Sun, 12 Apr 2020 18:25:39 +0000 To: Lane, Cliff (NIH/NIAID) [El Subject: RE:Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615, in Harrison's principles of internal medicine-20th Ed Thanks . --------------- (b)(6) From: Lane, Cliff (NIH/NIAID) [El Date: Sunday, April 12, 2020 2:24 PM --~ To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6) Subject: Re: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec t ions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed I responded to him and copied Kami Kim. He misread the two sections. We are saying the same things. I did not copy you. From: Anthony Fauci < Cb)(6) Date: Sunday, April 12, 2020 at 2:13 PM -------~~ To: "Lane, Cliff (N IH/NIAID) [E]" (b)(6) Subject: FW: Clarification in th e chapters on Human Immunodefici ency virus dis ease: AIDS and --------- related disorde rs ( Chapter 197 ) page 1445 and Toxoplasma infections ( Chapter 223 ) page 1615 , in Harrison's pr inc iples of internal medicine-20th Ed Please take a look at this. We get these inquiries from Ind ians all the time. very carefully. Is there anything we need to change here? They read HPIM (b)(6)> From: Viswanathan Neelakantan Date: Sunday, April 12, 2020 3:35 AM (b)(6) To: (b) (6); Fauci, Anthony {NIH/NIAID) [El __ ..:....;, ___ _;_.:....;_=======--Cc: Lane, Cliff (NIH/N IAID) [El (b)(6) Subject: Clarification in the chapters on Human Immunodeficiency virus disease: AIDS and related disorders ( Chapter 197) page 1445 and Toxoplasma infec tions ( Chapter 223) page 1615, in Harrison's principles of internal medicine-20th Ed ---------- Dear Professor Anthony Fauci and Professor Kami Kim, Greet ings from Pondicherry , India . This is Dr K Neelakantan Viswanathan, Senior Professor of Medicine in a medical school here. Going through your excellent chapter, [Chapter 197) in page 1445, on A IDS and related disorders in HPIM-20, under secondary prophylaxis/ maintenance therapy for Toxoplasmosis it is said that "it may be discontinued in the setting of effective cART and increases in CD4+ T cell counts to > 200 / microliter for 6 months". In page 1615, another wonderfully written chapter, ( Chapter 223) on Toxoplasma infect ions, Professor Kami Kim has mentioned that " individual s who have completed initial ther a py for TE should receive treatment indefinitely unless immune reconstitution with a CD4 + T cell cont of >200 occurs as a consequence of cART". Since both feature in the same textbook followed worldwide by medicos, could you please clarify the above? I stand subject to any correct ions. Hoping that we fight Covid-19 effective ly very soon . Stay safe. Regards and best wishes, Professor Dr K N Viswanathan From: Date: To: Subject: ScienceSpeaks: Fauci,Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 18:19:06 +0000 Daniel Lucey RE:COVID-19:Rembrandt' s Belshazzar's Feast in a time of chiaroscuro 2020 I Thanks , Dan. -----Original Message----·..--------,.-s-,:;aa. _ From: Daniel Lucey (b) ( Scot : Saturday, April 11, 2020 5: 14 PM To: Fauci , Anthony (N1H/NIAlD) [E] CbH Cc: Da ni el Lucey (bH > Subject: COVTD-19: Rembrandt 's Belshazzar' s Feast in a time of chiaroscuro 2020 I Science Speaks: --------- ~ Tony, Thank you for the immens e 24/7 contribution you are makin g to our nation. Your wife is right: Pis get more sleep and m eals! Before Easter tomo rrow I am s haring this brief Old Testament story to which I gave a 2020 interpretation. Today' s IDSA posting I am emphasizing that simultaneous antibody and virus RNA tests shou ld be done on "relaps ed" or "reinfected " Covid-19 patients e.g. , South Korea (N=91), China , elsewhere. I am looking forward to giving NIAID Grand Rounds May 1st with Barn ey Graham and John Beig e!. Dan (b)(6) https://sciences peaksblog .org/2020 /04/ 09/covid-19 -rembrandt s- belshazzars -foast- in-a-time-of-chiaroscuro-2020 / Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 18:12:0 1 +0000 Barton Haynes, M .D. RE:coach Kvi deo for DHVI Thanks, Bart. Glad to have you working on the COVID-19 issue. From: Barton Haynes, M .D . ._________ Se nt : Sunday, April 12, 2020 8:47 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: RE:coach K video for DHVI ------~= Cb) _(...,, 6)> -------- (b)(6)> Coach K and I came to duke on the same day in 1980 and (b)(6) ...when I was chair and he wasn't quite so famous, he used to see all my division chief recruits and help me recruit. He is a really good guy, as you know. Am on the francis Collins-appointed NIH working group for COVID19 vaccines, first meet ing in the am ... Will continue to flog CoV2 simultanelously while making good progress on HIV. This past week had 4 HIV SABS, CHAVD, an IPCAVD, an HIVRAD we have with Scripps, and our GMP unit.. ...all on line. Not messing around .... All went really, really well. Thanks for all you continue to do. Best bart -------- From: Fauci, Anthony {NIH/NIAID) [E] Date: Saturday, Apr il 11, 2020 10:32 PM To: Barton Haynes, M.D . ________ Subject: RE:coach K video for DHVI (b)(6)> _> Cb _~_ 6J> Very nice!! From: Barton Haynes, M .D. Se nt : Friday, April 3, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""' )(=6) Subject: coach K video for DHVI Hi tony; if you get a chance, here is a 3 min. video Coach K did last week for DHVI. I sent it to all 270 DHVI members and they were very inspired! Thanks for sending your interview with K. it is terrific. All the best B From: Jon Jackson (b)(6)> Date: Thursday, March 26, 2020 12:59 PM To: Barton Haynes, M.D. _________ Subje ct: Re: saw your video Cb _>_ C6J> https://www.dropbox.com/s/2f6b142lv63el0f/lMG Sent from my iPhone 0250.MOV?dl=0 From: Date: Cc: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:27:46 +0000 Folkers, Greg (NIH/NIAID) [E);NIAID OD AM Stover, Kathy (NIH/NIAID) [E);Leifman, Laura (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [El Subject: RE:Serosurvey To: OK. We can discuss . -------- (b)(6) From: Folkers, Greg {NIH/NIAID) [El Date: Sunday, April 12, 2020 11:26 AM To: NIAID OD AM Cc: Stover, Kathy (NIH/NIAID) [E) (b)( •>; Leitman, Laura (NIH/NIAID) [E) (b)(6); Routh, Jennifer {NIH/NIAID) [E) (b)(6) Subject: RE:Serosurvey -------- Marilyn Marchione: I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned t o do. (b)(5) Let us d iscuss in a.m. -----O riginal Message----From: Marchione, Marilynn CbH6l> Cc: Folkers, Greg (NIH/NIAID) [E] CbH6l>;Conrad, Patricia (NIH/NIAID) [E] CbH6);Stover, Kathy (NIH/NIAID) [E] CbH6l>;Leifman, Laura (NIH/NIAID) [E] (b)(6) Subject: FW: Serosurvey Hello Dr . Fauci, I hope you are stayi ng well in these trying times. I'm writing to request a chance to embed with a team doing a coronavirus serosurvey, to tell a public health story from the front lines as I believe I'm uniquely positioned to do. I've made a similar request to the CDC, but the nationwide reach of the NIAID serosurvey might make my proposal easier to consider, so I'm coming hat in hand to you as well. Twenty years ago, as a temporary CDCemployee during a four-month Knight Journalism fellowship , I had the opportun ity to take the EIScourse in Atlanta and then work on several CDC outbreak and disease invest igations . One was a serosurvey on Long Island after West Nile virus had recently emerged in the U.S. I headed one of a dozen CDCteams that included a driver, a phlebotomist and a health aide from the New York state and Suffolk County health departments. We went door-to-door to consent part icipants, get blood samples and do interviews on exposure and symptoms. I appreciate the tremendous scientific value that serosurveys offer and the kind of attention to detai l and study rigor that's needed to get reliable information. I'm also a longtime medical journalist who understands and is sensitive to confidential ity , et hical and privacy concerns. I've been recognized by my peers as a science writing leader . https :lj casw.org/ casw/ a rti cle/m ari lyn n-m arch ione-associated-press-wi ns-victor-coh n-prize I've attached some letters from CDCand othe r health officials regard ing my work on the serosurvey, a photo of the EISand CDCteam (that's me toward the right in the front row) and t he MMWR report resulting from our work . The field supe rvisor -- Dr. Anthony Marfin, now with t he global vaccin e group PATH ( (b)(6) is willing to speak t o you on my behalf. Dr. Richard Besser, now presiden t of the Robert Wood Johnson Foundat ion, was my fellowship superviso r and mentor at CDC. Others I worked with include Dr. Anne Schuchat, Dr. John Ward, Dr. Robert Tauxe and Dr. Lyle Petersen . And of course, you know me from nearly three decades of medical writ ing, includ ing the HIV/AIDS government trip to Africa when Tommy Thompson was healt hy secretary. The Associated Press reaches half of the world 's population every day. I hope to offer a story t hat I and the AP are uniquely able to provide , to show and explain how public health is done and how science is accompl ished during a pandemic . Thank you for considering my request. Marilynn Ma rchione Chief Med ical Writer The Associated Press (b)(6) mmarchione@ap.org Twitter: @MMarch ioneAP The information contained in this communication is intended for the use of the designated recipients named above. If the reader of this communication is not the intended recipient, you are hereby notified that you have received this communication in error, and that any review, dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please notify The Associated Press immediately by telephone at +1-212-621-1500 and delete this email. Thank you. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 202017:12:57 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Of course. No problem. (b)(6) From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 1:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ------~= -------- (b)(6)> Subject: RE: Wall Street Journal sto ry If he wants also to talk to me should I also talk to him? From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Date: Sunday, April 12 , 2020 1:09 PM --------~= To: Barton Haynes, M.D. ---------Subject: RE: Wall Street Journal story > (b)(6) Yes to your questions. From: Barton Haynes, M.D. _________ Date: Sunday, April 12 , 2020 1:06 PM To: Fauci, Anthony (NIH/NIAID) [E] -----~~ Subject: RE:Wall Street Journal story _,.> (b) (6) (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most impo rtan t mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] Date: Sunday, April 12, 2020 12:44 PM To: Barton Haynes, M.D. _________ Subject: RE:Wall Street Journal story --------~ Bart: No problem. Go for it! Best. Tony ~ Cb _)_(6) _' From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, --------~~ M.D . ..._ ________ Cb _) _(6) Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:10:22 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Thanks. From: Barton Haynes, M .D. ________ Cb) _ (...,, 6)> Se nt : Sunday, April 12 , 2020 1 :10 PM To: Fauci, Anthony {NIH/NIAID) [E] -----~~ (b)(6)> Subject: RE: Wall Street Journal sto ry I am going to refer him to you per the last note. Best bart From: Fauci, Anthony {NIH/NIAID) [E] (b) ( -------Se nt : Sunday, April 12 , 2020 1:09 PM To: Barton Haynes, M .D. -------~~ _________ > ., (b)(6)> Subject: RE: Wall Street Journal story Yes to your questions. From: Barton Haynes, M .D. _________ _,.> (b) (6) Date: Sunday, April 12, 2020 1 :06 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: RE:Wall Street Journal story -------- (b)(6)> I know you don't have time to answer these but if you do fine, if not, ok. Just don't want to screw something up. Is it fair to say that shelly was not only a mentor but a father figure. You and shelly were very close. also fair to say shelly was your most important mentor in your career? Tx bart From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Sunday, April 12 , 2020 12:44 PM ~_' To: Barton Haynes, M.D. --------~ _________ Cb _)_(6) Subjec t : RE:Wall Street Journal story Bart: No prob lem. Go for it! Best. Tony (b)(6)> From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> ------~~ -------- (b)(6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nat ion from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but t rue ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM -------~~- To: Barton Haynes, M.D . ________ _ )_ (_6),.... Cb Subject: Wall Street Journ al story Dr. Haynes , I'm a reporter from the Wall Street Journal and, more important , a friend of Ben's from Duke. l've written quite a bit about your mentor and friend Dr. Fauci in the last few weeks, and I'm working on another story now that I was hoping you might be able to help w ith. This story is about his mentor, Dr. Wolff , and how Dr. Wolff helped tum Dr. Fa uci into the person he is today. I would love to hear more about their relationship from your perspective. I know this is an insanely busy time, but would you have a few minutes to chat by phone ? Thanks very much for your help. I hope you're safe and well in Durh am. All best , Ben Ben Cohen The Wall Street Journal 212-416-3420 (o) (b)(6) c) ben.co hen@ws j.com From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 17:08:21 +0000 Neil Lacey - COOT RE:THANK YOU Thanks, Neil. I appreciate your note. Best, Tony From: Neil Lacey- COOT Se nt : Sunday, April 12, 2020 1:05 PM To: Fauci, Anthony (NIH/NIAID) [E) -----= (b=H=6J> Subject: THANK YOU Thank you Dr. Birx and Dr. Fauci: At a time when America needs it most both of you have courageously stood at the podium at the White House press briefings and explained what we all need to be doing during this paralyzing COVID-19 pandemic. When othe rs have failed to lead, multiple task forces have struggled prioritizing safety fi rst before economics, both of you have tag teamed presenting the data and the analytics of COVID-19 by decoding its complexities and giving us the "honest t ruth" in language that is easy to understand . The virus will end when it ends and not before. Thank you both for your service to the nation and for doing your jobs with conviction and commitment in doing the right thing - sticking to science and not yielding to politics . America is immensely grate ful for both of you telling us all what we need to hear and what we need to do . You are both giants in the world of medicine . Very appreciative, Neil Lace (b)(6) Sent from my iPhone From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 17:07:23 +0000 Barton Haynes, M .D. RE:Wall Street Journal story Bart: I would be happy to talk to him about Shelly. People like to make stories as opposed to reporting on a story. Shelly was one of my best friends and mentor , but I was me way before I met Shelly, and so I am not really sure what he means by saying that Shelly " ... he lped turn Dr . Fauci into the person he is today". Best, Tony ---------- ~= From: Barton Haynes, M.D Date: Sunday, April 12, 2020 12:45 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: RE: Wall Street Journal story -------- (b)(6) (b)(6)> Of course the reason I am asking is tha t it is presumptious for me to talk to him about shellys influence on you ....perhaps I should just refer him to you? Don't want to do anything either inappropriate, non helpful or what you don't what. Best bart From: Barton Haynes, M.D. Date: Sunday, April 12, 2020 12:26 PM To: Fauci, Anthony (NIH/NIAID) [E] _______________ -----------------=- :-:-= Cb _>_C6) Subject: FW: Wall Street Journal story Hi tony; the fellow who wrote the article about you as point guard for St. Regis and the nation from the Wall street journal wants to talk to me about shelly wolff and you per below. is that ok? I will of course say only those things that are unbelievable but true ....which are all wonderful.. ... best bart From: Ben Cohen Date: Sunday, April 12, 2020 10:31 AM To: Barton Haynes, M.D. Subject: Wall Street Journal story ----------------- -=-s:"'= ----------------- Cc: Birx, Deborah L. EOP/NSC (b)( 6) --------~= (b)( ---------- (b)(6) •>; Fauci, Anthony (NIH/NIAID) [El (b)( >; Lane, Cliff (NIH/NIAID) [E) Subject: Re: 15 minute Coronavrius machines I'll look into the possibility of freeing up a machine for investigation. Sean Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [El w rote: -------- MaLc. _~ ·----------------------------.. (b)(6)> ~ (b) (5) (b) (5) Tony Anthony S. Fauci , MD Director Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. National From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sun, 12 Apr 2020 12:30:19 +0000 Short, Marc T. EOP/OVP RE: 15 minute Coronavrius machines Marc: Thanks for the note . Understood . I wish you a peaceful and enjoyable day with your family. Best regards, Tony From: Short, Marc T. EOP/OVP (b)(6) Date: Saturday, Apr il 11, 2020 11:57 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Cc: Conley, Sean P. CDR USNWHMO/WHMU (b)(6) >; Lane, Cliff (NIH/NIAID) [E] Subject: Re: 15 minute Coronavrius machines ---------- Birx, Deborah L. EOP/NSC -~-~~====-,:___:_~ (b)(6)>; (b)(6) Dr Fauci, You correctly noticed the symptoms but misdiagnosed the root cause. I (bXS)PCE Apologies for a poo r poker face. Best wishes to you and your family for a blessed Easter celebration of our Savior's resurrection. Thanks for all you do, Marc Sent from my iPhone On Apr 11, 2020, at 10:15 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Marc: _______ _, (b)(6) Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 12:28:27 +0000 Eisinger, Robert (NIH/NIAID) [El FW: Fearing appointment Please respond as appropriate. -----Original Message----From: Daniel Kolliker _________ ~H=6)> (b Date: Sunday , April 12, 2020 4:53 AM To: Fauci , Anthony (NIH/NIAID) [E)._ _____ ------~~ (b _)_( _,> Subject: Fearing appointment Dear Mr Fauci, We are really wondering over here in Europe why you don't take a dedicated opinion on COVID-19 and share your opinion at the daily briefings to the extent of your personal believes. We really expect you to oppose the president wherever you have a different opinion, which we believe is based on facts. Please consider our request and don't let the president keep spre ading his lies to the people of the United States. We would really appreciate watching you on the briefing s telling the nation the truth that is based on your experience straight to the point. Thank you so much , Daniel Kolliker and acquaintances From: Date: Fauci, Anthony (NIH/N IAID) [El Sun, 12 Apr 2020 12:27:36 +0000 Lerner, Andrea (NIH/N IAID) [El To: FW: --------- (b)(4) (b)(4) Please take a look at th is and respond as you see fit. Thanks. Date: ----------------From: Sunday, April 12, 2020 5 :54 AM [E] To: Fauci, Anthony (NIH/NIAID) Subject: ------ (b)(6) ::;..,..-,= (b)(6)> ==========:---------------------- (b) (4) Dear Dr. Fauci I know that you are very occupied . (b) (4) Please handle the draft confidentially . Thank you very much! Sincerely, D. Novosel, Switzerland www.novosel.ch From: Date: To: Cc: Subjec t : (b)(6) Sat, 11 Apr 2020 22:57 :51 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Mascola, John (NIH/VRC) Teleconferenc e next week [El 1 have asked john Mascola to connec t with you to set up a conference call with john, me, Carl, Emily some time next week. Subject is out of the box chinking about COYID-19 From: Date: To: Subject: Eisinger, Robert {NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:08 :16 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Letter sent on behalf ofChancellor Jeffrey P. Gold, M .D. This is another email f rom Jeff Gold at UNMC in response to an email that you sent him. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infect iou s Diseases Nationa l Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)(6) From: Gold, Jeffrey P (b)( > Date: Saturday, Apr il 11, 2020 3:12 PM To: Fauci, Anthony {NIH/NIA ID) [E] (b)(6)> Subje ct: Re: letter sent on behalf of Chancellor Jeffrey P. Gold, M.O. -------=-=--== Tony, Many thanks for taking the time to respond. Please let me know if I can help in any way. Our mobile device app (developed with Apple) has been quite helpful and is growing in use (over lOK) as a screening, referral and surveillance tool for several user sets. Just one of the many areas we continue to develop . Best wishes jeff --------- (b)(6)> From: "M. Anthony S. Fauci" Date: Saturday, April 11, 2020 at 1:52 PM To: "Go ld, Jeffrey P" (b)(6) Subject: RE: let ter sent on behalf o f Chancellor Jeffrey P. Gold, M.D. Non-UNMC email Jeff: M any th anks for your kind not e. Hope that all is well with you . Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: -------------------- (b) (6) On Behalf Of Gold, Jeffrey P Date: Friday, April 10, 2020 12:57 PM To: Fauci, Anthony (NIH/NIAID) [E] ~_,: __ Cc: Gold, Jeffrey P -------~~ (b)(6) _;__:,..:.:==:===:;;--------(b)(6) Subject: Letter sent on behalf of Chancellor Jeffrey P. Gold, M.D. Importance: High April 10, 2020 Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases 5601 Fishers Lane, MSC 9806 Bethesda , MD 20892-9806 (b)(6) Dear Dr. Fauci: I write simply to thank you and congratulate you for your incredible efforts during the management of this pandemic as it reaches across our nation . The unique challenges that this pandemic has created have also created opportunities , and we here at the University of Nebraska Medical Center have proudly participated with our federal, state and local partners during this COVID-19 pandemic as well as over the last 16 years, having matured an extensive program in the research, education, and clinical components of highly infectious diseases and biocontainment. The UNMC Center for Global Health Security has been the umbrella organization that has organized all of these components and continues to have strong leadership from retired military public health as well as gifted research scientists from across the nation. As a co-founding partner of NETEC , as a recipient of the Regional Disaster Health Service Awards, and as a close collaborator with the Department of Health and Human Services, the Department of Defense, the Department of Homeland Security and the Department of State, we have enjoyed the opportunity to always "lean in" as the need arises. I am sure your days are full not only of the complex logistics and tension that fill leadership roles at this time but also maintaining a "steady hand on the rudder" as we navigate these challenging waters. I think back to my days at New York Presbyterian and Cornell Med, knowing that we are both Cornell Med grads, both did our residency and fellowship training in New York, and have had the opportunity to interact back so many years ago. I do remember quite well the first time that we met and have always reflected warmly at having even a brief opportunity to interact. I do not write to ask for anything but to just simply thank you for all that you continue to do and know that you always have a friend here in Nebraska. I wish you and your family the very best as we continue this journey. Most sincerely, (b)(6) Jeffrey P. Gold, M.D. Chancellor (b)(6) Administrative Associate I Chancell or Jeffrey P. Gold's Office University of Nebraska Medical Center 986605 Nebraska MedicalCenter ____ I Omaha, NE 68198-6605 (b_H_6)1 fax 402.559.4396 (b)(6) UNMCI Facebook[facebook .com] I Twitter [tw itter .com) I lnstagram (instagram.coml I YouTube [youtube.coml I Flickr lflickr.coml The informat ion in thi s e-mail may be priv ileged and confidential, intended only for the use of th e addressee(s) above . Any unauthorized use or disclosu re of this informat ion is prohibited. If you have received this e-mail by m istake, please delete it and immediately contact the sender . The information in this e-mail may be privileged and confidentia l, intended only for the use of the addressee(s) above. Any unauthorized use or disclosure of this informat ion is prohibited. If you have received this e-mai l by m istake, please delete it and immed iately contact the sender . From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 22:02 :38 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Please send me your cell phone#. COVID-19 Craig Schirmer Memo 04 .10 .20 .pd f To: Subject: Attachme nts: This email is from Jeffrey Sachs. Robert W. Eis inger, Ph.D. Special Ass istant for Scientific Projects Immediate Office of the Director National Institu te of Allergy aod Tnfectious Diseases National Institutes of Health 31 Center Driv e, Room 7A-03 Bethesda MD 20892 (b)(6) (b)( -----Original Message----From: Jeffrey Sachs Date: Saturday, April 11, 2020 4:50 PM -------, ~= (b) ( -----~~ ______ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Please send me your cell phone # . ___,> (b)(6) (b) (4) Looking forward to speaking , Jeff On 4/11/20, 4:28 PM, "Fauci, Anthony (NTH/NIA ID) [E)" -------- Mine is ----- (b)(6) (b)( wrote: From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:25 :18 -0400 Evans, Michele (NIH/NIA/IRP) [E] Re: Covid-19 Health Disparities Michele: Many thanks for your note. Best regards, Tony On Apr 7, 2020 , at 8:28 PM, Evans , Michele (NIH/NIA /IRP ) [E] (b) (6) > w rote: Dear Dr. Fauci, Thank you from the bottom of my heart for highl ighting the health disparities and dispropor tionate burden of disease influencing outcome of Covid-19 infections in African Amer icans. Participants in my observational, longitudinal, epidemiologic Baltimore -based study, HANDLShttps://handls.nih.gov/ are terrified by the level of disease they are seeing in their communit ies across Baltimore. We have been on the phone with and texting participants to educate them , support them in their efforts to get tested, remind them of the importance of social distancing and self-isolation when appropriate to protec t their health . We are acutely aware of the ir fragility. Testing in Baltimore is limited. The National Guard has set up community test ing at the Pimlico RaceTrack; however , although we have deployed our mobile medical research vehicles to Pimlico in the past to conduct our study, the current crime rate is such that our partic ipants and community residents in general do not go to the Pimlico area especially if they are on foot. The other issue with testing for African Americans and our participants is the need to have a health care provide r that one can contract to discuss symptoms to get a refe rral for testing. The unravelling of t he Affordable Care Act has severely impacted access for African Americans across the nation and especially in Baltimore . Our participants are calling my staff clinician and nur se practitioner for referrals if they have symptoms. We have reached out to colleagues at Health Care for the Homeless, JHU and other medical entities to facilitate access. Thank you all you are doing . Since I work in Baltimore, I haven't seen (b)(6) . The current pandemic however, reminds me of the days of the AIDS epidemic when I worked as Sam Broder's special assistant for underserved populations wh ile Peggy Hamburg worked for you . I was in awe of you and Sam then and I remain in awe of you today. I have known many Regis men ...but you are clearly head and shoulders above them all. Michele K. Evans, M.D. Deputy Scientific Director &Chief, Health Disparities Research Section National Institute on Aging National Institutes of Health NIH Biomedical Research Program 251 Bayview Boulevard Suite 100 Room 4C-222 Batimore, Maryland 21224 Email: (b)(6) Tel. (b)(6) https://irp .nih.gov/pi/michele-evans https://handls .nih.gov/ From: Date: (b)(6) To: Cc: Subject: Sat, 11 Apr 2020 16:22 :40 -0400 Janet Tobias Conrad, Patricia (NIH/NIAID) [El Re: Updates: Film ·----------- (b)(6) Janet All this sounds fine and workabl e. Thanks , To ny On Apr 7, 2020 , at 8:3 1 PM, Janet Tobias wrote : Dear Tony and Patty: Responses to Burklow 's questions to me from your group call yesterday: 1) I think we have landed in the right place for the film about yom life . Nat Geo, Di sney, and Bob Iger himse lf, all understand the need for discretion now but are wi ldly supporti ve about relea sing a film that will celebrat e the importa nce of yo ur life, science and public hea lth. I wan ted th e bes t hom e, broades t distribution , and strongest team for your film. You have entrusted me with yo ur sto1y, so I ju st want to do right by it. We are really happy wit h the filming that we have don e so far personal (b)(6) home, school) to work ( office etc) . 3) The other film we have been working on (ENDING AIDS), which fo llows globa lly the H VTN trials/latest Aids research to comp lete " the too lbox" is definitely still happening. It is now in pause with COVID-19 . . .. but will move forward again when we get through thi s. Filming at research sites in South Africa, US, and Latin America has been great...and when you have time - in the future- I w ill outline . You obviously are a key subjec t in ENDING AIDS also , but ENDING AIDS will spend a lot of time with doctors at the fie ld research sites and with volunt eers in the trials. The Aids conference and meetings footage we have shot wi th you wi ll be shared between films, smart ly and distinctly. END ING AIDS will be released a year plus later than the release of your biographical film- I am focuse d on your film now. Howard Hughes Medical Institute remai ns the educational pa1iner on ENDING AIDS. In the fall we will fina lize the broadcast/streaming partner for ENDI NG AIDS. So, bottom line it w ill be released a year after your film , and will be a film focused on showing in detail where we are now with aids research and the key people in the chain from you 10 a young fem ale voluntee r in South Africa/a you ng male volunteer in Binningham. FILMING REQUESTS for your film now. 4) NO more ask ing to film with the Task Force. 5) I do have two persona l filming requests for you - wo uld it be poss ible to drive to NIH wi th you once or twice a week and capture your working/ap propriat e conversat ions in the car. That will be so helpful narratively to tracking you r scientific and comm unic ation leadership . The footage we did that first day is truly great. We will just tum around and come back after the ride there--- in our follow car (we have NIH access badges) . Second ly, wou ld it be possible to sit down with you on camera for J 5 minutes once a week (on the weekend?) at the office or on the back deck/some safe location to talk with me in real time about what you are managing with treatments , vaccines , etc. so we can pull the scientific /conunw1-icatio11nanative on COVID-19 through your film. 6) We love the live truck and the walks, so whenever that works we will be there. 7) l NEV ER ever want to interfere with the work on the Task Force, lives are at stake. IF something doesn't work for filming no questions asked we don' t do it, we stop, cancel/pivot. No need to explain, the team here understands and only wants to do what works for you, your team ... , (b)( '1 . With appreciation , Janet From: Date: (b)(6) To: Subject: Sat, 11 Apr 2020 16:14 :53 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Invitatio n to speak to ABEA in virtual meeting No Begin forwarded message: From: "Allen , Clint (NIH/NIDCD) [E]" (b)( > Date: April 8, 2020 at 9:16:55 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" (bH6);> Subject: Invitation to speak to ABEA in virtual meeting Date: April 9, 2020 at 10:52:49 AM EDT To: NIAID OD AM Subject: F,v:Council of Scientific Society Presidents Support of Science Award Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confiden tial and may contain sensit ive informat ion. It shou ld not be used by anyone who is not the original intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Mosher, Sharon Date: Thursday, April 9, 2020 10:31 AM To: Fauci, Anthony (NIH/NIAID) [E] -------,;; Cc: Barasch, Kimberly (NIH/NIAID) [CJ (b""'"' )= (6) (b)(6b; Conrad, Patricia (b)( > (NIH/NIAID) [E] Subject: Council of Scientific Society Presidents Support of Science Award Dear Dr. Fauci; Council of Scientific Society Presidents (CSSP)would like to honor you with our Support of Science Award at our May Leadership Workshop (virtual). The purpose of th is award is to honor those who have pro ven the ir outstand ing support of U.S. science, free scientific communication, and a support of basic science research . The expertise with w hi ch you guide the United Sta tes through these unprecedented COVID-19 times simply reinforces the dedication you exhibit to ensure the greatest safety to the greatest number of US citizens . Dr. Martin Apple talked to Kim Barasch earlier this week. Please find the attached formal invitation letter she indicated that was needed. I have also attached a PDF of a brochure, though most information is on our webs ite . If you or Kim have any questions, please let me know by email or phone . Sincerely, Sharon M osher Sharon M osher FarishChair and Professor The University of Texasat Austin JacksonSchoolof Geosciences 2305 Speedway,Stop C1160 Austin, TX 78712-1692 (b) (6) (cell) smosher@jsg.utexas.edu (b)(6) From: Date: To: Cc: Subject: Sat, 11 Apr 2020 16:04 :03 -0400 Alison Galvani Conrad, Patricia (NIH/NIAID) [E);Seyed Moghadas ;Singer,Burton H Re: Your Submission THELANCETID-D-20-01518R1 Thanks, Alison On Apr 9, 2020, at 7:46 PM, Alison Galvani ---------- (b)(6)> wr ote: Hi Tony, I thought you might be interested in our projectio ns regard ing vent ilator needs in the US. The brief report (attached) was accepted at Lancet ID yes terday. Funded by NIAID :) Take care, Alison ---------- Forwarded message --------From: Phoebe Hall Date: Wed, Apr 8, 2020 at 9:36 AM Subject: Your Submis sion THELANCE TID-D- 20-01518Rl To: Galvani, Alison (b)(6) Dear Professor Galvani, Reference: THEL ANCETID-D-20-01518Rl, Projecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States I am pleased to tell you that your submission , Proj ecting the demand for ventilators at the peak of COVID-19 outbreaks in the United States, has been accepted for publication in The Lancet Infectious Diseases . In due course you will rece ive, electronically , a set of pdf proofs of your article . Plea se note that because of our varied and internatio nal readership, The Lancet Infectious Diseases edits heavily to a strict house style. Thus, changes will inevitably be made to your manuscrip t at this time. Th ere will also probably be a few final editorial queries at this stage. Please correct and return these pages by the deadline stated in the covering email. Finally, please note that The Lancet Infectious Disease s is committed to support authors in making their work publicly and freely available. The editors encourage authors to post a word-processed document (NOT the published journ al article as PDF) of their peer-reviewed, accepted article on personal or institutional websites any time after publication in print or online . Your document should include the article citation and a link to The Lancet Infectious Diseases's homepage . Please note that posting and distribution of PDF or HTML documents, however, is not acceptable and breaches your copyright agreement. Please complete the following Journal Publishing Agreement: https ://nam0 5. safe links. pro tee tion. ou tlook.com/?url =https%3 A %2F%2Fwww. thelan cet.com%2Fforauthors %2Fforms%3Fsec tion%3Djpa&data =02% 7C0 1% 7Calison.galvani%40 yale. edu¾ 7Cl c0ddd00e9ca4 l 3f77 l 008d 7d be 1e529% 7Cdd8cbebb2 l 394df8 b4 l l 4e 3e87abeb5c%7C0 %7C0%7C637219498130294598&:sdata =WoXBAmJN sM9 S Bkf aeGK.AzvAN g%2BSzbZAw94aO5%2BAtP%2FY%3D&:reserved =0 Please retain a copy for your files and email a completed copy to HALLP @science.regn.net. Please ensure all the pages are returned. WHO AUTHORS If you or any of your co-authors are employed directly by the World Health Organization , you have the option of either signing Elsevier 's standard agreement or our WHO/Elsevier non-exclusive licence agreement. Please contac t our Deputy Operations Manager, Marco Conforti (m.conforti @elsevier.com) for a copy of the WHO agreement. Yours sincerely , Phoebe Hall Senior Editor The Lancet Infectious Diseases E-mail: phoebe.hall @lancet.com In compliance with data protection regulations , you may reque st that we remove yow-personal registration details at any time. (Use the following URL: https ://nam05. safe links.pro tee tion.outlook.com /?url =https%3 A %2F%2Fwww. editor ialman ager.c om%2Fthelance tid%2Flogin.asp%3Fa%3Dr&:data =02% 7C0 1% 7C alison. galvani%40yale.edu% 7C 1c0ddd00e9ca413f77 l 008d7 dbc 1e529% 7Cdd8cbeb b21394df8b4 114e3e87abeb5c %7C 0% 7C0% 7C637219498130294598&:sdata=j KlkjtzfbMH6UMOPZ%2BvavnATDZkEB9y2up55tmx UA 5A %3D&:reserve d =0). Please contact the publication office if you have any questions. Alison Galvani , PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) http ://c i dma.yale.e du/ Follow me at @Alison_ Galvan; Follow CIDMA @YCJDMA Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:56:00 +0000 Jack Killen Auchi ncloss, Hugh (NIH/NIAID) [E] RE: From Jack Killen & Fred Boykin From: Date: To: Cc: Subjec t : Jack: (b)(6) Many th anks fo r you r kind note. Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Jack Killen (b)(6) Date: Tuesday, April 7, 20201 :31 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Auchinclo ss, Hugh (NIH/NIAID) [E] -------~~ (b)(6) ----------- (b)(6) Subje ct : From Jack Killen & Fred Boykin Dear Tony: This is a quick note to say Fred and I have been watch ing you every day, in awe, fo r weeks now. We could not be more grateful for your leadership, wisdom, courage, and integrity . Our country could not be more fortu nate that you are still there in guiding us through this terr ible time. Needless to say, many memories of our years working together have been in the forefront of our minds. On a ersonal note (b)(6) (b)(6) My epidem ic battling skills are rusty , but if there is anything I can do to help in any way, please know I are here for you. Fred is as well. Godspeed, and please take care of yourself. Best to you, JackKillen MD (b)(6) -----(b) (6land your family. From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Sat, 11 Apr 2020 19:50 :06 +0000 Georg e GAO RE: Vaccine - confidential PPT Geor ge : Thank you f or you r kind note . All is well despite some crazy people in thi s wor ld . Wa rm regard s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)(6) Date: Wednesday, April 8, 2020 4:36 AM -------=-:-=,(b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [El Subject: Re: Vaccine - confidential PPT Tony I saw some news (hope it is fake) that are being attacked by some peopl e. Hope you are we ll und er such a irrational situation. ___________________________ intro du ctio n. All the best and stay safe . Bw George Cb _>_(4) Thank you for your tt 2020~3~ 29 B, 09:07 , Fauci, Anthony (NIH/NIAID) [El -------- ~~ : (b)(6)> George: Thanks for the note. I understand completely. No problem. We will get through this toge t her . Bed regards, Tony On Mar 28, 2020, at 8:50 PM, George GAO_____ Cb _H_6J wrote: Dear Tony I know you are working extremely hard with a lot of pressure. Hope the US situation is getting bettereventully. I saw the Science interview, how could I say such a word "big mistake" about others? That was journalist's word ing. Hope you understand. It was NOT a real interview but a QaA through social media fo r several days when ge asked me what China has done and is working on. Lets work toget her to get the virus out of the earth. Best wishes George tt 2020~3~ -------- 3 B , 21:10, Fauci, Anthony (NIH/NIAID) [El (b)(6) ~~ : George: Thanks for the note. I will send th is to Dr. John Mascola Director of the NIAID Vaccine Research Cente r and Dr. Barney Graham to follow-up with you . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabil ity for any stateme nts made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: George GAO (b)( 6) Date: Tuesday, March 3, 2020 7 :12 AM To: Fauci, Ant hony (NIH/NIAID) [E] Subject: Vaccine- confidentia l PPT ------~~ -------- (b)( 6) DearTony Hope th is email find s you we ll and t he US will soon get t he COVID-19 down . (b) (4) All t he best George ~§fta-9 iPhone <20200303 For Gao laoshi.pptx> From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 11 Apr 2020 19:27 :03 +0000 Folkers, Greg (NIH/NIAID) [E) RE:ASF - note from Mary Jane Walker !! FW: Catching up Than ks, Mary Jane ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------.....,..,= --------, _;.. __ ..:...:.-.:.!:==~~~--- (b)(6)> From: Folkers, Greg (NIH/NIAID) [El Date: Thursday, April 9, 2020 10:23 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Maryja ne Walk er (b)(6) Subject: ASF- note from Mary Jane Walker!! FW: Catching up From: Maryja ne Walker Subject: Catching up Date: Apri l 6, 2020 at 9:23:13 PM EDT To: CbH6) (b)(6) Hi Tony, I hope that you are doing well despite all th at you are dealing with around COVID-19. It has been many years since I had the opportun ity to work wi th you but my job at NIAID was one of my favorite positions and gave me a great start to my career . So, when I saw the below graphic, it made me smile and I wanted to send yo u a note . I tr uly appreciate how you are handling the COVID-19 situation. Your comments are a breath of fresh air amidst poli ti cs and uncertainty . With daily Whi t e House press brie fi ngs, increased security and scrutiny, 24/7 media interviews and great popularity, yo u seem to be holding up well - as you always do. Your recent interview with JAMA's Editor-in-C hief Howard Bauchner was particularly well done and very enl ightening . Thank you for everything that you are doing and please stay healthy! Kind regards, Mary Jane Fauci, Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 18:35 :53 +0000 Crawford , Chase (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIA ID) [E);Billet, Courtney (NIH/ NIAID) [El;Haskins, M elinda (NIH/NIAID) [E);Selgrade, Sara (NIH/NIAID) [E) Subject: RE:Attn Dr. Fauci: Key Point s for Congressional Black Caucus Briefing Call Monday 11:30a .m. From: Date: To: Thanks. Please make sue that it is printed out mand given to me before the br iefing . Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other stor age devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Crawford, Chase (NIH/NIAID) [El (b)(6) Date: Friday, Apri l 10, 2020 7:19 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Billet, Courtney (NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda (NIH/NIAID) (E] (b)( >; Selgrade, Sara (NIH/NIAID ) [E] (b)(6) Subject; RE: Att n Dr. Fauci : Key Points for Congressiona l Black Caucus Briefing Call - Monday 11:30a.m. --------=-:-:-= Dr. Fauci, Attached is an updated "one- pager" for your call on Monday with members of the Congressional Black Caucus. At Greg's recommendation , we have added information on the NIH-supported serosurvey tha t was announced this afternoon. Please let me know if I can be of furthe r assistance {Chase cell : ------ CbH6)) Thanks, Chase From: Crawford, Chase (NIH/NIAID) [El Date: Friday, April 10, 2020 5:16 PM -----~ To: Fauci, Anthony (NIH/NIAID) [E] < Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Haskins, Mel inda {NIH/NIAID) => (b)( (b)(6)>; Billet, Courtney (NIH/N IAID) (E] [El (b)(6)>; Selgrade, Sara (NIH/NIAID) [E] (b)(6) Subject: Attn Dr. Fauci: Key Points for Congressional Black Caucus Briefing Call - Monday 11:30a.m. Dr. Fauci, On Monday, April 13t h, at 11:30 a.m., you are scheduled to part icipate in an informal di scussion / t elebriefing regard ing health dispari t ies and COVID-19 with members of the Congressional Black Caucus (CBC). Rep. Barbara Lee (D-CA, including Oakland and Berkeley) - former CBCchair - made the request. A list of expected call participan ts is below the signatur e line of thi s email. I have attached a "one-pager" to p rovi de some background on health disparitie s and COVID-19 that include s informat ion on NIH COVID-19 research that may be re levant to the di scussion . As you are aware, we do not have any COVID-19 stud ies directly focused on t he African American community. Hilary and Greg have provided input . Please let me know if I can be of furthe r assistance (Chase cell : Thanks, Chase List of CBCcall participants Rep. Barba ra Lee Rep. Karen Bass (CBC Chair) Rep. Robin Kelly (CBC Health Braintru st Chair) Rep. G.K. Butt er fi eld Rep. Yvette Clarke Rep. Cedric Richmond Rep. Brenda Lawrence ------ CbH6)) Rep. Steve Horsford Rep. Ayanna Pressley From: Fauci, Anthony (NIH/N IAID) [E) Date: Sat, 11 Apr 2020 18:10:39 +0000 (b)(6) To: Subject: FW: Wpost : Gilead's experimental drug remdesivir shows 'ho pefu l' signs in small grou p of coronavirus patients https://wapo.st/2wzjsy2 Geeez.... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, April 10, 2020 5:30 PM Subject: Wpost: Gilead's experim ental drug remdesivir show s 'hopeful' signs in small group of coronavirus patients https ://wapo.st/2wzjsy2 -------- Business Gilead's experimental drug remdesivir shows 'hopeful' signs in small group of coronavirus patients Two-thirds of severely ill patients showed improvement in their oxygen therapy level when treated with the antiviral drug wo ampuls of remdesivir are pictured during a news conference at the University Hospita l Eppendorf (UKE) in Hamburg, April 8, 2020, as the spread of coronavirus disease (covid-19) continues. Ulrich Perrey/Pool via REUTERS (Pool/Reuters) By Christopher Rowland April 10, 2020 at 5:25 p.m . EDT A major ity of a small group of patients showed improve ments after being treated with an experimental coronavirus treatment made by Gilead Sciences, bolstering hopes for finding a treatment for the disease, according to a study pub lished in the New England Journal of Medicine Friday. The group of patients received the anti -viral drug remde sivir as part of a "compassionate use" tria l, not a doub le-blind placebo-control led tria l which wou ld offer more definitive evidence. Also, the cohort of patients was small, only 53 patients in the United States and around the world . Those lim iting factors prevent scientists from declaring that the drug works . Still, the improvements offered positive news about a drug seen by global health authorities as offering the best shot at becoming a treatment for the disease. Thirty six patients out of 53 - or two-thirds - showed improvement in oxygen support, trial authors said. Seventeen of 30 patients who were on ventilators were able to be taken off the life-support machines. "We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful," said Jonathan D. Grein, MD, Director of Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, and lead author of the journal article. "We look forward to the results of controlled clinical trials to potentially validate these findings ." While 68 percent of the patients showed improvement in the level of oxygen support they needed, 13 percent died, the NEJM study said. That 13 percent compares favorab ly to mortality rates of 17 to 78 percent in China among severely ill patients, the authors wrote . Gilead's stock has been bolstered for weeks by expectat ions over remdesivir . Remdesivir was discovered by Gilead in t he hunt for antiviral drugs about a decade ago, and the Nationa l Institutes of Health has partnered with the company to explore its benefits. It was shown to work against an array of viruses in laboratory tests. It showed effectiveness in primates infected with Ebola but failed in a trial in the Democratic Republican of Congo in humans with the deadly disease. It has shown effectiveness as a preventive therapy in primates for MERS,which is a coronavirus cousin of the Covid-19 virus. There are no treatments approved by the Food and Drug Administration to treat coronavirus, but the FDA has granted an emergency use authorization for the use of hydroxychloroquine and chloroquine, two decades-old anti-malarial drugs. There is scant evidence that the therapy works, but President Trump has repeatedly boosted the promise of the drugs. Even while multiple full clinical trials of remdesivir continue, Gilead hasbeen swamped with requests for " compassionate use" of the drug . Under compassionate use rules, physicians can obtain experimental drugs for their seriously ill patients when there is nothing else to try. Gilead said last week that it had enough of the experimental drug on hand to trea t up to 140,000 people under compassionate use programs. 0 Comments Christopher Rowland Chris Rowland joined The Washington Post business team in 2018 after serving as the Washington bureau chief for the Boston Globe, leading coverage of two presidential elections and overseeing political enterprise reporting . He previously covered health care for the Globe in Boston.Follow Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 18:09:19 +0000 From: Date: (b)(6) Subje ct: https://bit. ly/2y3h3fi FW: New York er: How Ant hony Fauci Became Am eri ca' s Doct or This is th e actual arti cle fo r which I prev iously sent you a link. Anthony S. Fauci , MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: _ __,.,_, (b)(6) The information inlh ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Friday, April 10, 2020 4:30 PM Subject: New Yorker: How Anthony Fauci Became America ' s Doctor https://b it .ly/2y3h3fi Annals of Medicine April 20 , 202 0 Issue How Anthony Fauci Became America's Doctor An infectious-diseaseexpert's long crusade against some of humanity's most virulent threats. By Michael Specter April 10, 2020 ., I .. "You stay completely apolitical and non-ideological," Fauci says. "I' m a scientist and J 'm a p hysic ian. A nd that's it. " Illustration by Tyler Comrie. Photograph by Win McNamee I Getty Just before 1nidnight on March 22nd, the President of the United States prepared to tweet. Millions of Americans , in the hope of safeguarding their health and fighting the rapidly escalating spread of COVID-19 , had already begun to follow the sober recommendation of Anthony S. Fauci, the country ' s leading expert on infectious disease. Fauci had warned Americans to "hunker down significantly more than we as a country are doing." Donald Trump disagreed. " WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF ," he tweeted . Trump had seen enough of "social distancing. " In an election year, he was watching the stock market collapse , unemployment spike , and the national mood devolve into collective anxiety. "I would love to have the country opened up, and just rarin' to go by Easter ," he said, on Fox News. "You ' ll have packed churches all over our country . I think it'll be a beautiful time." Trump ' s Easter forecast came more than two months after the first U .S. case of COVID-19 was identified , in Washington State, and more than a hundred days after the novel coronavirus emerged , first from bats and then from a live-animal market in the Chinese city of Wuhan. Every day, more people were falling sick and dying. Despite a catastrophic lack of testing capacity , it was clear that the virus had reached every comer of the nation. With the Easter holiday just a few weeks away , there was not a single public-health official in the United States who appeared to share the President 's rosy surmises. Anthony Fauci certainly did not. At seventy-nine, Fauci has run the National Institute of Allergy and Infectious Diseases for thirty-six years , through six Administrations and a long procession of viral epidemics: H.I.V. , SARS, avian influenza , swine flu, Zika, and Ebola ainong them. As a member of the Administration's coronavirus task force, Fauci seemed to believe that the government's actions could be directed , even if the President's pronouncements could not. At White House briefings , it has regu larl y fallen to Fauci to gently amend Trump's absurdities , half-truths, and outright lies. No, there is no evidence that the malaria drug hydro xychloroquine will provide a "miracle" treattnent to stave off the infection . No, there won't be a vaccine for at least a year. When the President insisted for many weeks on denying the government's inability to deliver test kits for the virus, Fauci, testifying before Congress , put the matter bluntly. "That 's a failing," he said. "Let's admit it." When Trump was not dismissing the sever ity of the crisis , he was blaming others for it: the Chinese , the Europeans, and, as always, Barack Obama. He blamed governors who were desperate for federal help and had been reduced to fighting one another for life saving venti lator s. In one briefing, Governor Andrew Cuomo , of New York , said, "It's like being on eBay with fifty other states, bidding on a ventilator." Trump even accused hospital workers in New York City of pilfering surg ical masks and other vital protecti ve equipment that they needed to stay alive. "Are they going out the back door?" Trump wondered aloud. As a reporter who writes mainly on science and public-health issues , I've known Fauci since the H.I.V ./AIDS epidemic exploded , in the rnideighties. He once explained to me that he has developed a method for dealing with political leaders in times of crisis: "I go to my favorite book of philosophy , ' The Godfather ,' and say , 'It's nothing personal, it's strictly business.' " He continued, "You just have a job to do. Even when somebody's acting ridiculous , you can't chide them for it. You 've got to deal with them. Because if you don't deal with them , then you're out of the picture." Since his days of advising Ronald Reagan and George H. W. Bush, Fauci has maintained a simple credo: "You stay completely apolitical and non-ideological, and you stick to what it is that you do. I'm a scientist and I'm a physician. And that's it." He learned the value of candor early. "Some wise person who used to be in the White House, in the Nixon Administration, told me a very interesting dictum to live by," he told me in 2016, during a public conversation we had at the fifty-year reunion of his medical-school class. "He said, 'When you go into the White House, you should be prepared that that is the last ti1ne you will ever go in. Because if you go in saying, I'm going to tell somebody something they want to hear, then you've shot yourself in the foot. ' Now everybody knows I'm going to tell them exactly what's the truth." Americans have come to rely on Fauci's authoritative presence. Perhaps not since the Vietnam era, when Walter Cronkite, the avuncular anchor of the "CBS Evening News," was routinely described as the most trusted man in America, has the country depended so completely on one person to deliver a daily dose of plain talk. In one national poll, released last Thursday, seventy-eight per cent of participants approved of Fauci's performance. Only seven per cent disapproved. On March 23rd, Fauci failed to appear at the daily briefing in the White House pressroom. Twitter promptly lost its mind. #NoFauci became a top trending topic, followed closely by #whereisFauci and #letTonyspeak. There was speculation that Trump, who is inclined to fire anyone who disagrees with him or, worse, garners some praise in the media, had lost patience with Fauci . As one of Fauci's old friends told me, "This is a President who doesn 't give a shit about Fauci's accomplishments, his history, or his learning. If anything, they're negatives." The truth was less alarming. "I was tied up in a task-force meeting , and we were trying to work out some difficult policies ," Fauci said. "I have no trouble with the President. When I talk to him, he listens." My experience with Fauci suggested that this last statement was perhaps a triu1nph of pragmatism over accuracy. His priority, as he's made clear , is to do what is necessary to save lives. So I was not surprised to receive an e-mail from Fauci the following day, saying that he had been asked to refrain from participating in personal profiles. It seemed that it was one thing for him to talk about the news with reporters or even to chat on Instagram with Stephen Curry, the Golden State Warriors star. But focussing on himself, rather than on the President, was another thing entirely. Fauci and Trump are about as odd a duo as American political life has ever produced . Both men are in their seventies. Both come from the outer boroughs of New York City. Both are direct, even blunt. But that's where the resemblance ends. Fauci has always been a person of unusual discipline. Nearing eighty, he works about eighteen hours a day. Long ago, when his three children were young , he and his wife , Christine Grady, who runs the bioethics department at the National Institutes of Health , decided to maintain the sanctity of family dinners by starting them when he got home from the office, at around nine o'clock. For decades , Fauci has taken long lunchtime runs, but, during the crisis, he 's cut back his routine to power walking- and only on weekends. Fauci parses his words with care and believes , above all, in the power of facts and the efficacy of data. ADVERTISEMENT David Baltimore , a Nobel laureate and a pioneer of molecular biolog y, told me, "Tony is unique , in that he has such credibility with politicians that he's been able to insert hard facts into the conversation. That has been wonderful for our country and the world." According to David Relman, a microbiologist at Stanford University who for years has advised the government on biological threats , "Tony has essentially become the embodiment of the biomedical and public -health research enterprise in the United States. Nobody is a more tireless champion of the truth and the facts. I am not entirely sure what we would do without him." Fauci can be impatient with the compromises of politics . In my conversations with him, he has responded furiously when a dicey amendment, a bogus rider, or a "poison pill" is attached to a publ ic- health bill. He recalled one congressional provision, in 2016 , that tried to make it "legally permissible to fly the Confederate flag at national cemeteries. I am not kidding. " When dealing with politician s, he told me, he relies on the pseudo-Latin expression Illegitimi non carborundum: Don't let the bastards grind you down. But he has inspired respect throughout the political world and beyond. Fauci ' s office walls are covered with scores of photographs of him with Presidents , senators , visiting Prime Ministers , business leaders , actors. In October, 1988, George H. W. Bush , during a Presidential debate with Michael Dukakis , was asked who his heroes were. "I think of Dr. Fauci ," Bush replied. "You 'v e probably never heard of him .... He's a very fine researcher , a top doctor at the National Institutes of Health , working hard, doing something about research on this disease of AIDS. " These days , nearly everyone has heard of Fauc i. Pandemic-memorab ilia entrepreneurs have put his face on bottle openers , coffee mugs , and bumper stickers: "In Dr. Fauci we trust. " The National Bobblehead Hall of Fame and Museum has produced a seven-inch likeness of him , partly to raise money to produce protecti ve gear for medical workers. There's a Facebook group called Dr. Fauci Speaks , We Listen, and another called Dr. Fauci Memes for Social Distance Teens. A petition has circulated to nominate him as People' s "sexiest man alive." On right-wing social media and talk radio, Fauci has a different image: he is routinely disparaged as a closet lefty who is exaggerating the threat of the corona virus. "Has anyone else noticed that every suggestion by Dr. Doom Fauci just happens to also be the worst pos sible thing for the economy?" the conservati ve Internet TV host Bill Mitchell tweeted . "That's not an accident folks." An analysis in the Times found more than seventy Twitter accounts that have pushed the hashtag #FauciFraud , with some tweeting out anti-Fauci bile hundreds of times a day. "There see1ns to be a concerted effort on the part of Tru1np supporters to spread misinformation about the virus, " Carl Bergstrom, a professor of biology at the Uni versity of Washington who has studied misinformation , told the paper. "There is this sense that experts are untrustworthy , and have agendas that aren 't aligned with the people." Fauci has received so many personal threats that the Justice Department recently appro ved a security detail for him. Fauci shrugged it off, telling reporters, "I've chosen this life." The crisis that the world now faces comes as no surprise to Fauci. On January 10, 2017, ten days before Trump took the oath of office, Fauci delivered the keynote address at a conference at Georgetown University , titled "Pandemic Preparedness for the Next Administration. " After describing his years of managing epidemics, he posed a series of questions to the audience: "Will there be a resurgence of Zika? We 're getting into the summer in South America. Are we going to see a resurgence or not? What about influenza? Are we going to get a new pandemic?" Fauci's last point, he emphasi zed, was almost certainly the most important: the possibility that some unknown , powerfully infectious pathogen could emerge to threaten the world. "What about things that we 're not even thinking about?" he said. He let the question drift out over the hall. "What is for sure," he concluded , "is that, no matter what, history has told us definitively that it will happen." On the day that Anthony Stephen Fauci was born , the front-page headline in the Times was "P RESIDENT TO GIVE EMERGENCY FACTS TO NATION ON RADIO." It was Christmas Eve, 1940. The Second World War had begun, and the United States was less than a year away from joining the fight. Fauci grew up in southwest Brooklyn , first in Bensonhurst and later in Dyker Heights , where his family ran a pharmacy and lived in an apartment upstairs. The pharmacy was across the street from the Shrine Church of St. Bernadette. When Mass was finished on Sundays , Fauci recalled, people would walk over to get prescriptions filled and to buy whatever else they needed for the coming week. Tony's father, Stephen, dispensed medications , and was known to customers as Doc. His mother, Eugenia , worked the register, along with his older sister, Denise. From an early age, Tony spent evenings and weekends riding around the neighborhood on his Schwinn , making deliveries. Fauci's parents were born in New York; one set of grandparents had emigrated from Naples, the other from Sicily. Anthony first took Communion at the age of seven and was confirmed at twelve. He went to elementary school at Our Lady of Guadalupe, in Bensonhurst. "I had no idea at the time when I was there, being taught by the Dominican nuns, that I would be interested in science," he said. "I was interested in a lot of things, mostly sports, but certainly not science." In those days, baseball was the social glue of Brooklyn. The borough was Dodger territory and Ebbets Field was consecrated ground- but Fauci was devoted to the Yankees , who played in the faraway Bronx. In the midst of the coronavirus crisis, I e-mailed to ask about this anomaly, not necessarily expecting an answer. He replied almost instantly. "You probably are unaware, but half the kids in Brooklyn were Yankee fans," he wrote. "We spent our days arguing who was better: Duke Snider versus Mickey Mantle ; Roy Campanella versus Yogi Berra ; Pee Wee Reese versus Phil Rizzuto and on and on. Those were the days, my friend." Fauci has often referred to his father as "laid-back," which , if true, must be a characteristic that skips a generation. "Tony has always been driven ," Michael Osterholm , the director of the University of Minnesota's Center for Infectious Disease Research and Policy, and a longtime friend of Fauci ' s, told me. "Whatever he was doing, he had to do it better than anybody else. I don't know if it was certainty or something else. But he was meant to lead. Always. Everyone who knew him knew that. And Tony knew it, too." In 1954, he began attending Regis, a private Jesuit high school on the Upper East Side. Rigorous, small, competitive, and tuition-free, Regis is considered one of the finest all-male schools in the country. Fauci thrived there, though the commute between Dyker Heights and Eightyfourth and Madison was long. He once estimated that he had spent the equivalent of seventy days of his teen-age life on the various subways and buses he took to get to and from school. Fauci revelled in the demanding coursework. "We took four years of Greek, four years of Latin , three years of French, ancient history , theology ," he recalled. He developed an ability to set out an argument and to bolster it with evidence- good preparation, it turned out, for testifying before Congress . Last year, at a dinner that Regis held in his honor, he said that the school had taught him "to communicate scientific principles , or principles of basic and clinical research, without getting very profuse and off on tangents." At the time, though, Fauci had no interest in becoming a doctor. "I was captain of the Regis High School basketball team," he once told me. "I thought this was what I wanted to do with myself. But, being a realist, I very quickly found out that a five-seven, really fast, good-shooting point guard will never be as good as a really fast, good-shooting seven-footer. I decided to change the direction of 1ny career." At school, Fauci 's accomplished peers were headed to careers in medicine, engineering, and the law. At home, he was steeped in the humanities: "Virtually all my relatives on my mother's side-her father, her brother, and her sister's children-are artists." His mother helped tip the balance. "She never really pressured me in any way, but I think I subtly picked up the vibrations that she wanted very much for me to be a physician," Fauci said. "There was this tension-would it be humanities and classics, or would it be science? As I analyzed that, it seemed to me that being a physician was the perfect melding of both of those aspirations.'' From Regis, Fauci went on to another Jesuit institution , Holy Cross, in Worcester, Massachusetts. His high-school faculty had left him little choice in the matter. "They just wouldn't write a recommendation for you if you wanted to apply to Harvard or to Cornell, or Columbia," he said. Fauci enrolled in 1958 and was pleased to find that the university took a broad view of premedical studies. He signed up for a program called Bachelor of Arts- Greek Classics- Premed. "It was really kind of bizarre," he recalled. "We did a lot of classics, Greek, Latin, Romance languages .... We took many credits of philosophy, everything from epistemology to philosophical psychology, logic, etc. But we took enough biology and physics and science to get you into medical school." During the summers, Fauci worked construction jobs. One year, he found himself assigned to a crew that was building a new library at Cornell Medical College, on the Upper East Side. "On lunch break , when the crew were eating their hero sandwiches and making catcalls to nurses, I snuck into the auditorium to take a peek," Fauci recalled in 1998, at the medical school 's centennial celebration. "I got goosebumps as I entered, looked around the empty room, and imagined what it would be like to attend this extraordinary institution. After a few minutes at the doorway, a guard came and politely told me to leave, since my dirty boots were soiling the floor. I looked at him and said proudly that I would be attending this institution a year from now. He laughed and said, 'Right , kid, and next year I am going to be Police Commissioner. ' " Fauci graduated first in his class from Cornell in 1966, just as America's involvement in Vietnam was accelerating. Every new physician was required to perform some kind of military service. "We were gathered in the auditorium at Cornell, early in our fourth year of medical school," Fauci recalled. "Unlike today, we had only two women in the class and seventy-nine men. The recruiter from the armed forces came there and said, 'Believe it or not, when you graduate from medical school at the end of the year, except for the two women, everyone in this room is going to be either in the Army, the Air Force, the Navy, or the Public Health Service. So you're going to have to make your choice. Sign up and give your preferences.' " Fauci wanted to work in the U.S. Public Health Service; his fallback was the Navy. He got his first choice , and ended up at the National Institutes of Health , which was then establishing itself as the country's primary center for biomedical research. Nearly everyone in academic medicine spent some time at one of its branches; except for three years back at Cornell to complete his internship and residency, Fauci has spent five decades there. In 1972, Fauci started as a senior researcher at the National Institute of Allergy and Infectious Diseases. He was drawn to investigating ailments that were difficult but not impossible to treat. "I wanted something that could make you very sick and kill you unless I intervened. And if I intervene, you're essentially cured," he told Ushma Neill, the editor of The Journal of Clinical Investigation, in 2014. "Now, that seems a little bit too simplistic, but that's really the nature of most infectious diseases." Working in the lab of Sheldon Wolff, Fauci studied the molecular nature of fever. The field of immunology was still young, but scientists were rapidly learning how to manipulate the smallest components of individual cells, which opened the way to a decade of discovery. Chronic fevers can have a number of underlying causes, among them an uncommon condition known as vasculitis- an inflammation of the blood cells that often occurs when the body's immune system mistakenly attacks its own blood vessels. Many of Fauci's vasculitis patients suffered from rare inflammatory diseases, such as granulomatosis with polyangiitis , which damages blood vessels in the lungs, kidneys, and other organs. The disease was almost always fatal. Fauci and his infectious-disease colleagues at the N.I.H. were frequently asked to visit the National Cancer Institute, which was in the same building as his lab, to consult on patients who were receiving chemotherapy. The drugs suppresse d tumors, but they were highly toxic. And they had another side effect , Fauci told me: "Those people are susceptible to a lot of things like infections and bleeding, because the treatment has destroyed their immune systems." In 1990, Fauci was the government's leading researcher foc ussed on the AIDS epidemic. Photograph by George Tames/ The New York Times/ Redux Fauci, together with Wolff, his mentor, wondered if this side effect could be harnessed to help vasculitis patients, whose immune systems were overact ive. "I thought if we could somehow give a cancer drug at a low enough dose perhaps we could tum the disease off without any of the secondary complications ," he recalled recently. "First we did it in a few patients, and, much to our delight, they had a total remission. Before you know it, we ended up curing a very, very lethal, albeit uncommon, disease." For the first time, this techn ique enabled researchers to do effective work on lupus, rheumatoid arthritis, and transplant rejection. "If you look at innnunology, it has fro1n the very beginning been inextricably linked to infectious diseases ," Fauci said. "What is the immune system for? The immune system protects you against invaders from withoutmicroorganisms - as well as, in some cases, the emergence of certain tumors from within." In 1981, a strange new syndrome emerged that transformed Fauci's research and, eventually , the lives of millions of people around the world. "All of a sudden, this new disease comes along," Fauci recalled , referring to what would soon come to be known as AIDS. "Even before the cause of it was proven to be H.I.V., everybody in the field knew that it had to be a virus. I said to myself, 'Here it is, a virus, still to be determined, that's affecting profoundly and destroying the human immune system. ' "Fauci believed that he had been training all his life for a threat like this one. He was an expert in viruses and in the immune system-and he had always been attracted to combatting serious, even fatal diseases. "I wanted to be where the action was," he said. At first, few public-health officials seemed to care. In June of 1981, the Morbidity and Mortality Weekly Report , a publication of the Centers for Disease Control , issued a paper that included an account of five young men, all gay , who had contracted pneumocystis, a form of pneumonia that had previously been reported only in people with dramatically impaired immune systems. The young men described in the study had all been healthy. "I thought it was a fluke," Fauci recalled. "I put it aside on my desk, thinking that maybe this was some drug that they had taken that suppressed their immune system." A month later, an even more alarming report arrived from the C.D.C. Fauci read it with an uneasy sense that a disaster was looming: "I made the decision that I was going to stop what I was doing , much to the chagrin of my mentors, who were saying, 'Why do you want to give up a great trajectory of a career to study a handful of gay men with this strange disease?' But, deep down, I really knew that this was going to explode. " Fauci wrote a paper to sound the alarm. "I called it my apologia pro vita sua- an explanation for what I'm doing," he said. In the paper , Fauci pointed out that, although the disease "seems to selectively affect a particular segment of our society," it demanded a medical solution. Moreover, he warned, "any assumption that the syndrome will re1nain restricted to a particular segment of our society is truly an assumption without a scientific basis." Fauci sent the manuscript to The New England Journal of Medicine, in late 1981. It was rejected. "One of the reviewers said I was being alarmist," Fauci said. He tried a different journal , The Annals of Internal Medicin e, and the following June the paper was published. In the laboratory , Fauci began making progress. He had been investigating B cells, which are involved in the production of antibodies. In 1983-before H.I.V. was even known by that name-his lab became the first to report that B cells became hyperactive in patients with AIDS. When a healthy person is invaded by a virus , antibodies mount a defense, but, when H.I.V. hijacked B cells, the antibody system went awry. Fauci and his team had identified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said in an interview for an N.I.H. oral history. "I think that speaks for sound scientific and clinical observation." The politics of seeking a cure, though, would be far harder to manage. On October 11, 1988, more than a thousand AIDS activists gathered outside the headquarters of the Food and Drug Administration , in Rockville, Maryland, to protest the agency's glacial reaction to the epidemic. The activists knew that their community needed new treatments if they were to avoid catastrophe - but they were stymied by the F.D.A.'s drug-approval process , a remarkably inflexible system that typically took years. That same day, another group of protesters marched onto the campus of the National Institutes of Health, in Bethesda , Maryland. They were headed for Building 31, the home of the National Institute of Allergy and Infectious Diseases. Fauci , who had become the institute's director in 1984, was now the government's leading scientist focussed on the AIDS epidemic. Even though he was not running the F .D.A., he appeared almost daily in the media to discuss the crisis. "My face was the face of the federal govermnent ," Fauci told me. He was asked the same question nearly every day: why wasn't the government moving faster ? It didn't help that the Reagan Administration seemed so indifferent to the plague. Fauci watched from his office window as activists surrounded the building and tried to scale its walls. Some were dressed in black robes and carried scythes. Many waved pink-and-black banners, bearing the words "NIH Wake Up!" or "Stop Killing Us!" All over campus , a chant could be heard: "Fuck you, Fauci!" "God, I hated him," Larry Kramer, the writer and activist who helped establish the two most important AIDS advocacy groups in the country, the Gay Men's Health Crisis and ACT UP , said. "As far as I was concerned, he was the central focus of evil in the world." Kramer attacked Fauci relentlessly in the media. He called him an "inco1npetent idiot" and a "'pill-pushing" tool of the medical establishment, insulted his wife, and even compared him to Adolf Eichmann. In 1988, Kramer published a scathing open letter. "Anthony Fauci , you are a murderer," he wrote. "Your refusal to hear the screams of AIDS activists early in the crisis resulted in the deaths of thousands of Queers. " As the epidemic spread and the death toll rose, it was common for gay activists to view Fauci and NIAID with rage. Fauci did not control the drug-approval process , but he was seen as a barrier to opening access to clinical trials , in which volunteers could receive potentially lifesaving medications. For most people infected with H.I.V. , taking experimental drugs was the only alternative to simply waiting for death. Yet the F .D .A.' s arcane rules prevented the vast majority of patients from qualifying for trials. For instance, a significant number of H.I.V. patients suffered from pneumocystis pneu1nonia. The condition-the same one observed in the initial C.D.C. report- could be fatal, so many who had it used an experimental antimicrobial medication called pentamidine, which had proved highly effective. But people who took experimental medications were barred from participating in other clinical trials. At first, Fauci held to the standard N.I.H. line that research need not focus on the immediate welfare of patients. "When we had clinical trials, we, the scientific co1nmunity and the regulatory co1nmunity, did not listen" to the activists , he recalled. "It was, at the time, an attitude that many of us had, and I probably had it myself." He was right about that. I covered the AIDS epidemic for the Washington Post, and it was clear to me that Fauci was inclined to enforce the paternalistic medical tradition in which he had trained: doctors and scientists were unquestioned authorities, and drug development had to follow a rigid process that included animal testing and rigorous clinical trials. Otherwise , the benefits and the risks of these drugs could not be adequately assessed. In 1987, the F.D.A. approved the first drug to treat H.I.V.azidothymidine, or AZT-and the announcement was met with a burst of hope. But the drug's liabilities were evident almost instantly. It had harsh side effects, and the benefits wore off; the virus itself soon became resistant to the drug. When new clinical studies began , involving cocktails of AZT and similar compounds, tens of thousands of people asked to participate. Again, though, volunteers were not accepted if they used other experimental drugs. The anger among activists grew 1nore intense. "They started becoming amazingly iconoclastic and confrontational, and that scared the hell out of the scientists, who were fundamentally quite conservative ," Fauci told me at his medical-school reunion. "When they were demonstrating on the N.I.H. campus, disrupting Wall Street, disrupting St. Patrick 's Cathedral, instead of listening to them, scientists withdrew." Without entirely understanding his own motives, Fauci decided to look beyond the activists' furious rhetoric and style. He recalls telling himself, "Let me put aside the goth dress-the earrings and the Mohawk haircuts and the black jackets-and just listen to what they have to say. And what they were saying made absolutely perfect sense." It helped that Fauci had something in common with the activists: "They were all New York guys. I had a little affinity to them because I'm a New Yorker. And I said, What would I do if I were in their shoes? And it was very clear: I would have done exactly the same thing." The activists knew that they were facing a mercilessly lethal disease. In the summer of 1985, I travelled to New York to write my first long story on the toll that the epidemic was taking on the city's gay community. I interviewed dozens of 1nen. To the best of my knowledge, only two of them are still alive: Larry Kramer , who is now eighty-four, and a political activist who prefers to remain anonymous. Fauci, too, came to understand the severity of the crisis. "Everyone died," he said. "I was used to treating people who had little hope and then saving their lives-that was so wonderful. But, with AIDS in those days, I saved no one. It was the darkest time of my life." Faced with mounting evidence that his cautious approach made no sense , he did something that few public officials do: he reversed himself. Fauci transformed from a conventional bench scientist into a public-health activist who happened to work for the federal government. "I had to change ," he told me. When the demonstrators marched on the N.I.H . campus in 1988, Fauci no longer saw a threat. "I looked at them, and I saw people who were in pain," he recalled in an article in Holy Cross Magazin e. He asked the police and the F.B.I. not to arrest any of the1n. Then he invited a handful of protest leaders to his office. "That began a relationship over many years ," Fauci said. "They let me into their camp. I went to the gay bathhouses and spoke to them. I went to San Francisco, to the Castro District , and I discussed the problems they were having , the degree of suffering that was going on in the community, the need for them to get involved in clinical trials , since there were no other possibilities for them to get access to drugs. And I earned their confidence." Fauci, in his mid-forties, was the youngest director of an N.I.H. institute in a century , and he lacked the political influence to act independently. Even in his own field , he struggled to recruit allies. "I couldn't convince my own people in infectious-disease leadership to take on H.I.V ./AIDS ," he told me. So he created a division within his institute devoted to the disease. One day, in the late eighties , Fauci asked me to stop by his office in Building 31 on the N.I.H. campus. He told me that he had a wild idea: he wanted to hire Mark Harrington , ACT UP' s point man on drug-treatment trials. Harrington, a prominent AIDS researcher and activist, had no formal scientific training. But Fauci , like most of those who had seen him testify before Congress or speak to a crowd , was dazzled by his brilliance. Harrington discussed the idea with Fauci , but decided that the job would be a disaster for him. "There's no way I could have functioned within that bureaucracy, " he told me recently. "The people I respect would have seen me as a sellout." Yet Harrington continued to make a profound impression on Fauci' s thinking . Harrington was passionately committed to loosening up the F.D.A.'s restrictive regime. "It was murder," he told me. "I don't know any other way to describe it." Harrington, who went on to win a MacArthur "genius" grant for his work on the disease, established himself as the most knowledgeable student of the agency ' s byzantine regulations. In meetings with Fauci and other officials, he urged them to move faster and with greater compassion for those who were suffering. There are three stages in most F.D.A. clinical trials. The first tests whether a drug is safe. The second assesses its efficacy. The last stage , conducted in larger groups, confirms that the drug works and that there are no serious adverse reactions. Harrington argued that people with no alternative should be granted access to those drugs as soon as they had been proved safe, even if their effectiveness remained unknown. At first, Fauci was concerned that, if people taking multiple experimental medications joined clinical trials , the results would be hopelessly muddled. He was also afraid that granting sick people unrestricted access to unapproved drugs would deter them from participating in the trials at all. Harrington and other activists reassured him that they were committed to strictly monitored drug trials that would provide enough data to know what worked and what did not. Fauci is a realist, and the facts were obvious to anyone who cared to look. Traditional methods of testing drugs weren't working. Underground networks were growing everywhere. With so many AIDS patients taking untested medications , federal health officials had to concede that their syste1n was broken. Even the most fundamental protocol of a clinical trial- giving some participants a placebo- came into question. In a study conducted in San Francisco in 1989, nearly all the volunteers had their medicine analyzed, to see whether they were receiving an active dose. Those who learned that they had been given placebos almost invariably dropped out. "There was a feeling in science that doctors know best, scientists know best," Fauci said. "We love our patients, but they don ' t really know what's best for them. Then, when we dealt with this disease that was brand new- that was frightening, that was killing people in a way that was historic-the people who were impacted by the disease wanted to have something to say about how we conducted research." There were still moments of confrontation. In May, 1990, hundreds of ACT UP activists returned to the N.I.H., demanding more AIDS treatments and greater representation of women and people of color in clinical trials. At a planning session for the protest, a young activist named Tony Malliaris performed a rap song called "Storm the NIH ," which included the lyrics "I don't know what Fauci thinks, but this ain't Denmark, and something stinks." (Malliaris died five years later, still in his early thirties.) Fauci was undeterred. He threw his influence behind a program called Parallel Track, which made unapproved AIDS drugs available as soon as they were demonstrated to be safe, even as clinical trials were continuing. The initiative would not have succeeded without Fauci. But he always acknowledged that his approach had been shaped largely by the constructive pressure he received from AIDS advocacy groups and from leaders like Harrington. This more inclusive approach ushered in a revolution in American medicine . Patients today demand as much information as possible about treatments they might receive , and no longer act as if their doctors ' advice came straight from Mt. Olympus. They scour the Internet, assemble statistic s, and often arrive at the hospital with a folder full of medical information. The F.D.A., for its part, will no longer consider approving a new drug until it has consulted representatives of groups who would use it. "There are strict scientific principles that have to be adhered to in medicine ," Fauci told me. "At the same time, a humanistic touch is needed in dealing with people. You have to combine social aspects, ethical aspects, personal aspects with cold, clean science." In 2002 , I wrote a Profile of Larry Kramer for this magazine. By then, he and Fauci had become friends , with each expressing gratitude for the other's work in those years. Fauci told me , "In American medicine , there are two eras: before Larry and after Larry. There is no question in my mind that Larry helped change medicine in this country. When all the screaming and the histrionics are forgotten, that will remain." Kramer, who spent years in a constant rage at Fauci , now calls him "the only true and great hero" among government officials in the AIDScrisis. As Trump defends his Administration's response to the pandemic, he has suggested repeatedly that COVID-19was impossible to predict. "There's never been anything like this in history ," he said, at a press conference on March 19th. "Nobody knew there would be a pande1nic or epidemic of this proportion." As everyone with even a casual interest in the history of science knows, pandemics have altered the destiny of humanity at least since 430 B.C., when Athens was struck by a plague that killed as many as two-thirds of its residents , just as the Spartans were laying siege. Beginning in 165 A.D. , smallpox helped ruin the Roman Empire , sowing more destruction than foreign armies ever could. And, in the fourteenth century, the Black Death swept through Europe , killing more than half the population, according to recent estimates. Yet, by the middle of the twentieth century, many scientists had begun to conceive of a world that was largely free of infectious epidemics. In 1951, Sir Frank Macfarlane Burnet, a future Nobel laureate in medicine , wrote, "The fever hospitals are vanishing or being turned to other uses. With full use of the knowledge we already possess, the effective control of every important infectious disease"-with the exception of polio-"is possible. " His optimism was understandable. Antibiotics had made many lethal diseases easy to treat; improvements in sanitary conditions had transformed the lives of hundreds of millions of people. In developed countries, typhoid, cholera, and measles - major killers throughout history - had largely passed into memory; even tuberculosis , one of the great scourges of humanity, had been in decline for nearly half a century. By 1972, Macfarlane , writing with the microbiologist David White, was predicting that the "most likely forecast about the future of infectious diseases is that it will be very dull." When Fauci was a young trainee, these kinds of predictions sometimes made him wonder if he had picked the wrong career. "I became concerned that I was entering ... an area of biomedical research that was disappearing ," he recalled in one speech. But , since 1984 , when Fauci became the director of NIAID, there has not been a single day in which some epidemic has not threatened the globe. According to the World Health Organi zation, AIDS has killed more than thirty million people, and nearly forty million are now living with H.I.V. Tuberculosis, far from sliding into obscurity, infects roughly a quarter of the human population ; the W.H.O. says that one and a half 1nillion people died from the disease in 2018. But the greatest threat that humanity faces, by far, is a global outbreak of a lethal virus for which no treatlnent has been found. In just a few months , COVID-19 has forced billions of people , in nearly every country on earth , into a panicked withdrawal from society. Another pandemic like this might appear in two years, or in ten, or in a century. But I have never met a virologist or an epidemiologist who believes we won't encounter one. For a deadly virus to flourish, it must meet three critical conditions. First, a new virus-one to which no one has yet developed immunitymust emerge from the animal reservoirs that produce and harbor such pathogens. Second , the virus has to make humans sick. (The vast majorit y do not.) Finally, it must be able to spread efficiently, through coughing, sneezing, or shaking hands. That combination is rare, but , when it appears, the consequences are almost always disastrous. The Nobel Prize-winning molecular biologist Joshua Lederberg, who died in 2008, was for years the world's most visionary voice about emerging infectious diseases. "Some people think I am being hysterical , but there are catastrophes ahead," he once wrote. "We live in evolutionary competition with microbes - bacteria and viruses. There is no guarantee that we will be the survivors." In 2003 , Lederberg joined the future F.D.A. commissioner Margaret Hamburg and the pandemic specialist Mark Smolinski to edit a seminal report, in which prominent scientists argued for a much more aggressive defense of the planet. Titled "Microbial Threats to Health," the report recommended that the U.S. greatly expand its early-warning systems, particularly in the developing world. It also urged leaders to strengthen their ability to respond to microbial threats, with new efforts on the federal, state, and local levels. The recommendations were almost completely ignored. The next year, a highly pathogenic form of avian influenza, H5Nl, leaped from waterfowl to chickens and then to humans. Public-health officials were petrified. In Bangkok , I met with Scott Dowell, who led the Thailand office of the C.D.C.'s International Emerging Infections Program. "The world just has no idea what it's going to see if this thing comes," he told me. He paused and then reframed his thought. "When, really. It's when. I don't think we can afford the luxury of the word 'if anymore." In a sense, the world was lucky with H5Nl. Although the U.S. and other countries mounted a diffident response, the virus turned out to be deadly but not very contagious. Five years later, the situation was reversed. A new influenza virus, designated HINI, infected nearly a quarter of the global population before vaccines became widely available. This time, the virus was highly contagious but not nearly as deadly as most strains of influenza. The fact that the outbreak was less virulent than publichealth officials had feared created its own danger; by encouraging complacency, it did more to expose the world to the risk of a devastating new pandemic than anything else that had happened in decades. Although Congress had appropriated money to stockpi le antiviral medications and protective gear, many scientists felt that the effort was grossly insufficient. "We spend many billions of dollars every year on missile-defense systems," Seth Berkley, a medical epidemiologist who leads the Global Vaccine Alliance, told me. "And yet we will not spend pennies on the dollar to prepare for a catastrophe that is far more likely to affect us all." After the Ebola outbreak of 2014, Barack Obama implemented one of Lederberg's central rec01nmendations: he established the White House's National Security Council Directorate for Global Health Security and Biodefense, an early-warning system for disease in the developing world. Trump disbanded it in 2018 , as part of an effort to streamline the N.S.C. In an appearance before Congress, Fauci was asked if the decision was a mistake. He responded diplomatically: "I wouldn't necessarily characterize it as a mistake. I would say we worked very well with that office. It would be nice if the office was still there." The combination of mone y and political will can have extraordinary effects on public health. Under the George W. Bush Administration, Fauci was the principal architect of a landmark program called PEPFAR, the President's Emergency Plan for AIDS Relief. By the time Bush took office, therapies for H.I.V. had become widely available in Western countries. But, for millions of people in the developing world, these drugs were too expensive or too difficult to obtain. Bush felt that it was unacceptable for the poorest people on earth to die because they could not afford medication that was dispensed routinely in the rich world. He asked Fauci to implement an initiative to prevent and treat H.I.V. on a global scale. It has been uniformly held up as a model of the ways in which global public-health programs can save lives. "PEPF AR has turned around declining life expectancies in many countries and likely saved some countries-even an entire continentfrom economic ruin," Harold Varmus, a former director of the N.I.H. and of the National Cancer Institute , wrote in the quarterly journal Science & Diplomacy. But Fauci has at times struggled to compel politicians and businesses to attack the problems that he considers most worrisome. Over the years, he has become concerned about the possible impact of new viruses, particularly a lethal strain of influenza. Other viruses are more consistently deadly; some , like measles, are more contagious. But no virus that we know of is capable of killing as rapidly and as efficiently. "We need a major paradigm shift with influenza vaccines ," Fauci told me, four years ago. "The situation is a mess." Because the flu virus evolves so rapidly, experts deciding how to formulate vaccines can make only a highly educated guess about which strains are most likely to make people sick. Each February, epidemiologists study outbreaks around the world-especially in the Southern Hemisphere, where flu season is under way- to assess which strains might make their way north. The result is always better than nothing. In many years, though, it is woefully inadequate. In the flu season of 2014-15 , the vaccine protected less than a fifth of the people who received it. In 2017-18, it worked for a little more than a third. Fauci has long supported the development of an alternative: a universal influen za vaccine, which would provide lasting defense against all strai ns. "Similar to tetanus, a universal flu vaccine probably would be given every ten years, " he said. "A nd, if you get one that is really universal , you can vaccinate just about everyone in the world." But such a vaccine would cost hundreds of millions of dollars to develop and test- and would replace a product that most consumers already think of as good enough. No one has come close to raising the money that such a project will require. By the beginning of the new millennium , it had become clear that the next microbial threat might not come from a bat or a duck. It could just as well be created by a human being. After the terrorist attacks of September 11, 2001, anonymous letters laced with deadly anthrax spores began arriving at media companies and congressional offices. In the following months, twenty-two people were infected by inhaling anthrax and five died. Suddenly , biological terror posed an entirely new threatone that has become only more significant and complex in the ensuing years. In 2016, James Clapper, who was the director of National Intelligence during the Obama Administration , listed gene editing as a potential weapon of mass destruction. Many scientists were furious, but he had a point. Researchers have deployed these tools to rewrite the genes of mosquitoes so that they are unable to transmit malaria. If their success in the lab translates to the field, it will be a historic triumph. But the research also raises an alarming possibility: if a scientist can modify the genes of an insect to protect people from malaria, he could almost certainly use the same technology to add a deadly toxin. Fauci often cites a similar but more immediate paradox. Thanks to genetic engineering , we are more equipped than ever to respond to the threat of a viral pandemic. After the COVID -19 outbreak began, it took scientists less than a month to sequence the genome of the virus. By the end of February, the instructions were on the Internet, and the virus had been re-created in laboratories around the world, by scientists seeking to develop drugs and vaccines. And yet , despite our mastery of molecular biology, we live in an era in which someone can wake up with an infection in China-or France , Australia, or any other place with an airport - and fly to San Francisco in time for dinner, spreading the virus long before he suspects that there ' s anything wrong. For most of human history , a virus like COVlD-19 might have killed many people in the community where it originated, but then stopped spreading. According to a comprehensive analysis carried out by the Times, at least four hundred and thirt y thousand people have arrived in the U .S. on direct flights from China since the outbreak began. Forty thousand have arrived in the two months since Trump imposed restrictions on travellers from China trying to enter the country. Fauci insists that an adequate defense against future pandemics will have to be flexible . "I have been saying for eight , ten years that we should make a list of microbes and try to develop a basic platform vaccine," he told me in 2016. A platform vaccine addresses an entire class of virus, not just a particular strain. "We keep trying to develop a vaccine for one thing-usually the last one-and it's a waste of time ," he said. "Every time we get hit , it is always something we didn ' t expect. So, instead of predetermining what it is you're going to prepare for, make universal platforms. " Such an approach is eminently possible. Using gene-sequence information and synthetic DNA , biologists are now capable of making parts of a vaccine in advance . It takes almost no time to sequence a viral strain , and with that information it should be poss ible to complete a bespoke vaccine in a matter of weeks. "You could build a chassis for the vaccine, and you would have it on the shelf," Fauci said. "Then all you would need to do is insert the gene of the protein you want to express and make a gazillion doses and send it out. " There are even more futuristic aspirations: the genomics pioneer J. Craig Venter has proposed using a sort of 3-D printer to manufacture vaccines on demand. It is already possible to print the nucleotides that make up DNA and asse1nble them. Venter argues that , in the time it takes for an infected person to fly from one side of the world to the other, we should be able to print , assemble, and admini ster a vaccine. To even contemplate creating these kinds of treatments, Fauci says, would require building an entirely new system for making vaccines before a pandemic arises. But, in addition to the scientific obstacles , this would cost billions of dollars , and no company or politician has been willing to spend the money. Perhaps , just as AIDS transformed our approach to clinical trials , our experience with co vro-19 will change our attitudes about preventing infectious diseases. A proper investment in both research and emergency preparedness would have prevented at least some of the unspeakable human loss we are now experiencing and the economic crash that has just begun. The COVID-19epidemic will eventually fade, but the public will demand a reckoning. Inevitably, there will be an investigation , along the lines of the 9/ 11 Commission , to look into the ramifications of the President's denialism, the shortages in testing and medical equipment, and the dismissal of so many warning signs. Fauci will not necessarily escape criticism. He is an excellent spokesman for the value of scientific research, but he runs a single institute , and he lacks the authority to broadly reshape our response to pandemics. "The kinds of things we really desperately need as foundational tools for dealing with this stuff aren 't necessarily research enterprises," Harold Varmus told me. "Tony isn't running C.D.C. He's not running FEMA . To tell him to stockpile defense mechanisms or to move forward surveillance tools into massive operations around the world- that ' s just not his remit." Even Fauci' s current value as a scientific adviser has been limited by the President's conte1npt for expertise. Trump ' s coronavirus kitchen cabinet consists of people like his son-in-law, Jared Kushner, who has no medical knowledge or experience managing crises-yet has been appointed to direct the response to the biggest medical emergency since the influenza pandemic of 1918. Trump has also turned for advice to Dr. Mehmet Oz, who for years has endorsed worthless treatments and used his television show to promote notorious quacks. Trump even seems to think that his trade adviser, Peter Navarro, should debate Fauci about the value of specific drugs. When Navarro , who has a doctoral degree in economics, was asked about his medical qualifications , he said, "I have a Ph.D. And I understand how to read statistical studies, whether it's in medicine, the law, economics , or whatever." Among Navarro ' s enthusiasms is the malaria drug hydroxychloroquine , which he believes could cure COVID-19. There is currently no evidence to support this conclusion , as Fauci has pointed out on several occasions. On April 5th, as Trump continued to tout the drug as a miracle cure, a reporter at the daily briefing asked Fauci to com1nent. Trump refused to allow him to speak. In an appearance two days later, Trump kept up the hype. "I say try it," he said. "You're not gonna die from this pill." Not long afterward , he even suggested that zinc might help. To plan a coherent biological future , rather than simply scramble to contain each new pandemic , will require an entirely new kind of political commitment. It would certainly include the creation of a permanent position , a special assistant to the President for biological defense. Similar job s have existed in the past, but not for long , and not with enough influence to matter. David Reiman , the Stanford professor , told me, "This kind of job needs somebody with the authorit y to preside over domestic and international threats, both natural and deliberate. And that person has to sit in the White House with immediate access to the President. Without that , we will really have nothing that can work." Until then, we have Fauci, a seventy-nine-year-old infectious-disease expert pinned between Donald Tru1np and the American people. It can 't be easy. As Fauci recently put it, with characteristic candor, "I give the appearance of being optimistic. But, deep down, I just do everything I possibly can, assuming that the worst will happen , and I've got to stop the worst from happening." ♦ Published in the print edition of the April 20, 2020 , issue, with the headline "The Good Doctor ." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, witho ut further verification of its accuracy/veracity. It does not necessar ily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:30 :40 +0000 Del Rio, Carlos; (b)(6) (b) (6)· Cc: Subjec t : RE: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection Thanks, Carlos . As you know since Cliff has been in touch with the lDSA , the HHS guidelines will be coming out this week. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and lofectious Diseases Building 3 I, Room 7 A-03 31 Center Driv e, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301) 496-4409 E-ma il: (b) (6) The infom1ation in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. lfyou have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National lnstirute of Allergy and Infectio us Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Del Rio, Ca rlos ______ (b ""')'""" (= Date: Saturday , April J 1, 2020 12:08 PM To: (b)(6) ; Fauci , Anthony (NTHINIAID) [E] (b)(6) Subject: Jnfectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID - 19 Infection IDSA guide lines are out https://www.idsociety.org /prac ti ce-gu idel ine/ covid- 19-guidel ine-trea tment-and-manag ement/ Carlos de ! Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the int ended recipient(s) and may contain confident ial and privi leged information. If the reader of this message is not the intended recipient, you are hereby notified that any dissemination , distribution or copying of this message (includi ng any attachments) is strictly prohibit ed. Jfyou have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (inc luding attachments). From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 16:25 :29 +0000 To: (b)(6) Subject: FW: Infectious Diseases Society of Ame rica Guidelines on the Treatment and Management of Patients with COVID-19 Infection Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in enor please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Del Rio, Carlos ______ (b ""~"'(= Date: Saturday, April 11, 2020 12:08 PM To: (b)(6); Fauci, Anthony (NIWNIAID) [E] CbH > Subject: Infectious Disea ses Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Infection lDSA guidelines are out https://www.idsociety.org/practice-guideline/ covid-19-guideline-treattnent-and-management/ Carlos del Rio, MD. Sent from my iPhone This e-mail message (including any attachments) is for the sole use of the intended rccipicnt {s) and may coi,tain confid ential and privi leged information. If the reader of this message is not the intended rec ipient, you are hereby notified that any dissemina tion, distributio n or copying of this mess age (including any attachments) is strictly prohibit ed. lf you have received this message in enor, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:12:24 +0000 From: Date: (b)(6) Subject: FW: Atlantic's coverage - Fauci as "h eartthrob" David Bradley is the Chairman of The Atlantic. Geeez .... From: David Bradley Date: Friday, April 10, 2020 10:20 AM ------ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Atlantic's coverage - Fauci as "heartthrob" ~~ (b)(6h Hi Tony, ----- CbH6JI send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedica ted a who le art icle to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children, in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony -fauci -coronavirus crush/6095 44/ My best wishes to you. David David G. Bradley Chairman Atlantic Media Fauci,Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 15:10:47 +0000 David Bradley RE:At lantic's coverage- Faucias "heartthrob" From: Date: To: Subject: David: Many thanks for sending this. safe and well. Warm regards, Tony I could not have even begun to make this up ..... Please stay From: David Bradley Date: Friday, April 10, 2020 10:20 AM To: Fauci,Anthony (NIH/NIAID) [E]_______ Subject: Atlantic's coverage - Fauci as "heartthrob" ---------=-c-= Cb_H _6) Hi Tony , ----- (b)(6) I send you greetings and the deepest appreciation. I am only one of your millions of fol lowers who feel in your debt. But, I am the only one with a magazine that has dedicated a who le article to "the thirst for Tony Fauci." This will be the least important item on today's to-do list. But, someday, your grandchildren and their children , in turn, will want to read t his: https://www.theatlantic.com/technology/archive/2020/04/anthony-fauci-coronaviruscrush/609544/ My best wishes to you. David David G. Bradley Chairman Atlantic Media From: Date: Fauci, Anthony (NIH/N IAID) [E) Fri, 10 Apr 2020 01:37:52 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (N IH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] FW: Letter from Rep. C. Smith to Sec Azar and Dir Fauci 2020-04-09 Smith to Azar and Fauci re Lyme and COVID19.pdf To: Cc: Subject: Attachments : FYI From: Griswold, Kelsey Date: Thu rsday, April 9, 2020 8:41 PM To: Griswold, Kelsey ----------~~ (b)(6) (b)(6)> Subject: Lette r from Rep. C. Smith to Sec Azar and Dir Fauci Good Evening All, Attached is a letter from Congressman Smith to Secreta1y Azar and Director Fauc i. Please let me know if there are questions or concerns associated with this. Best, KelseyA. Griswold I LegislativeDirector CongressmanChristopher H. Smith (NJ-04) 2373 Rayburn HOB Washington, DC20515 p: (b)(6) From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 10 Apr 2020 01:35:00 +0000 To: (b)(6) RE:We Believe in You Subject: (b)(6J: Many thanks for your e-mai l. Stay well and safe. Best regards, Tony From: Cb)( Date: Thursday, April 9, 2020 8:07 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= Subject: Re: We Believe in You ---------- CbH6J Tony, I would only hope that one of your staff see my email and are prudent to know that this is being sent to him by one of his kin and passes it along to you. Sincerely, (b)(6) On Thursday, April 9, 2020 , 05 :54 :17 PM EDT , Fauci , Anthony (NIH/NIAID) [E] wrote : ------- (b)(6) My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message . I would encourage you to visit www.coronavirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci , M.D. From: Date: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Thu, 9 Apr 2020 21 :24:50 +0000 To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: COVID 19 Briefing Document and COVID Vaccine Overview Attachme nts: Overv iew of COVID-19 Vaccine Development_April9.pdf, Briefing Document NIAID Involvement with Pharma in COVID19_A pril 9_with table.pdf The email below is from Larry Corey. Robert W. Eisinger, Ph.D. Special Assistant for Scientific Project s Immediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email : (b)( From: Corey MD, Larry (b)(6)> Date: Thursday, April 9, 2020 3:50 PM ------ ~= To: Fauci, Anthony (NIH/NIAID) [El (b)( ·>; Conrad, Patricia (NIH/NIA ID) [El (b)( ; Marston, Hilary (NIH/NIAID) [El (b)(6)> Cc: Mascola, John (NIH/VRC) [El (b)(6) ; Erbelding, Emily (NIH/NIAID) [El --------- -----=~ Cb _>_C6) _ >; Dieffenbach, Carl (NIH/NIAID) [El (NIH/NIAID) [E] CbH6J Subject: COVID 19 Briefi ng Document and COVID Vaccine Overview (b)(6)>; Lane, Cliff Tony, We are sending you two documents relating to our strategy for COVID vaccine development . The (b) (4) (b) (4) Larry From: Date: (b)(6) To: Subject: Thu, 9 Apr 2020 17:18:14- 0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: INTERVIE W REQUEST with Or Anthony Fauci - Radio-CanadaNews Program 24h/60min Let us discuss Begin forwarded message: From: NATHA LIE L EMIEUX Date: April 9, 2020 at 5:02:20 PM EDT To: "NIAID NEWS (NIH/NIAID)" , "Fauci, Anthony (NIH/NIAID) [E]" (b)(6l , "Fauci, Anthony (NIH/NIAID) [E]" (b)C Subject: INTERVIEW REQUEST with Dr Anthony Fauci - Radio-Canada News Program 24h/60min Hello My name is Nathalie Lemieux and I am a rnsearch journalist for 24b in 60min, an information and public affairs program hosted by Anne-Marie Dussault and broadcast on the CBC/Radio-Canada's French national news network. https://ici.radio-canada.ca/tele/24-60/site We are based in Montreal and the broadcast is aired across Canada weekdays on prime time (between 7pm and 8PM ET) As we are also living thr ough this Covid-19 pandemia , we would be delighted to do an interview with Dr Anthony Fauci *Of course, host Anne-Marie Dussault can do the interview in English When: subject to Dr Fauci's availability ... How: Skype or Facetime (in respect of containment obligations) How long: 7-8 min Cou ld this proposal be of inte rest to Dr Fauci? Thank you for letting me know the possibilities ... we are aware of Dr Fauci's tight schedu le You can reac h me at any time via this emai l natha lie .lemieux@radio-canada.ca or on my cell phone: Cb) (6) Nathalie Lemieux Joumalis te a la recberche Emission 24 heures en 60 minutes RDI/Radio-Ca nada Cell: CbH6) 4il~Rao10 -canaoa From: Date: (b)(6) Thu, 9 Apr 2020 16:51:32 -0400 Stover, Kathy (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia To: Cc: (NIH/NIAID) [E] Subject: Re: FORASF REVIEW:Draft PR re: SARS-CoV-2 serosurvey study launch Looks fine ! Thank s On Apr 9, 2020, at l :48 PM, Stover, Kathy (NIH/NIAID) [E] (b) (6) wrote: Hi Dr. Fauci, Please find attached for your review a draft press release announcing the launch of Dr. Memoli's serostudy to detect previously undiagnosed coronav irus infections. Your draft quote is as follows: "Thi s study will give us a cleare r pichrre of the true magnitude of the COVID-19 pandemic in the United States by telling us how many people in different commun ities have been infected without knowing it, because they had a very mild, undocumented illness or did not access testing while they were sick," said Anthony S. Fauci, M.D., NIAID director. "The se crucial data will help us measure the impact of our public health efforts now and guide our COVID-19 response moving forward." Thanks much, Kathy Kathy Stover Branch Chief News and Science Writing Branch National Instit ute of Allergy and Infect ious Diseases (NIAID) Office of Communications and Government Relations National Institutes of Health/HHS 31 Center Drive, Room 7A17E Bethesda, MD 20892 Phone: (b)(6) ,__ (b)(6) E-mail: _____ NIAID Media Line: (301) 402-1663 From: Date: To: Subject: Inspector General Fauci, Anthony (NIH/N IA ID) [E) Thu, 9 Apr 2020 16 :40:28 +0000 Cb ) (6>:E) FW: New Yorker: Fauci Urges Trump to Attack the Coronavirus as if It Were an This Borowit z guy is some thin g else .... Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (3 96':44li 9 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Thursday, Apr il 9, 2020 12:33 PM To: NIAID COGCORE; NIAID OCGR Leg ; NIAID OD AM Subject: New Yorker : Fauci Urges Tru mp to Attack the Coronavirus as if It We re an Inspector General Satir e fro m The Bo rowitz Report Fauci Urges Trump to Attack the Coronavirus as if It Were an Inspector General By Andy Borowitz April 8, 2020 Photograph by Lo Scalzo/ Bloomberg/ Getty WASHINGTON (The Borowitz Report) - ln what he described as a "potentia lly major breakthrough," Dr. Anthony Fauci has convinced Donald Trump to attack COVID-19 as if it were an inspector general. Fauci, who has been frustrated in his efforts to get th rough to Trump, compared the global pandemic to an inspector general while in a closed-door meeting with the President on Wednesday. "Wha t do you hate more than anything, M r. President?" Fauci asked. "Jim Acosta," Trump immed iately replied. "O.K., fine. But, besides Jim Acosta," Fauci said, "it would be an inspecto r general, right?" "You're right, Tony," Trump agreed. " I hate those losers." "Well, think of COV/0-19 as the worst inspector general in the world," Fauci continued. " It's overseeing everything you do and making you follow the law. It's keeping you fr om spending taxpayer money on anything you want. You wouldn't stand for that , would you?" Reportedly, Trump appeared shaken by Fauci's analogy. "Damn it, Tony, when you put it that way, we've got to do something about COVID-19," he said. Speaking to reporters, Fauci said that he was "caut iously optimistic" that his inspector -genera l analogy would finally spur Trump to action, but added, "Jared could still screw this up." Disclaimer: Any third-party material in this email has been sha red for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 9 Apr 2020 10:17:45 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Mediaset, Italian television broadcast, interview request FYI From: Alessandro Matarante Date: Thursday, April 9, 2020 5:49 AM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Barasch,Kimberly (NIH/NIAID) [C) ;Conrad, Patricia {NIH/NIAID) [E) Subject: Mediaset, Italian television broadcast, interview request Hello Dr. Anthony Fauci, I'm Alessandro Matarante , an italian reporter , curr ently work ing for M ediaset, Italy's most imp ortant television broadcast. Specifically , I work fo r Quarta Repubb lica, a progra m aired every Monday in prime-time, leaded by reporter Nicola Porro. I'm writing this e-mail because it would be a pleasure and an honor for us to interview you about the coronavirus emergency and the way the United States are facing it. Clearly, we are availabl e to cons ider any ki nd of day and hour to make t he intervi ew, and so w e are to consider together the contents of the interv iew . Hoping for a posit ive answer, I wish you a pleasant day . Alessandro (b)(6) https://www .mediasetpla y .mediaset.it/programm i-tv/quartarepubblica b100002038 From: Date: (b)(6) To: Subject: Wed, 8 Apr 202017 :17:42 -0400 Lusso, Paolo (NIH/NIAID) [E] Re: Research Day organized by the Italian Embassy Paolo: I am very, very sorry, but I just cannot do this right now. I am swamped and my time is not my own. I hope that they understand . Best, Tony On Apr 8, 2020, at 4:00 PM, Lusso, Paolo (NIH/NIAID) [E] (b) (6)>wrote: Dear Tony: I am sorry to bother you with another request during this period. The Italian Embassy is organizing its yearly Research Day (Giornata della Ricerca) that this year will be held str ictly online (via Zoom or other e-meeting tool) and centered entirely on the Coronavirus pandemic. The Italian Ambassador, Mr. Varricch io, would be delighted if you accept to be his guest of honor at the event and asked me to informally enquire with you, before sending an official invitat ion, if there is any chance you could part icipate. He understands how crazy your schedule is during this crisis. They would like you to deliver a 30 min lecture on a theme of your choice, preferably related to the state of the art of the pandemic management. The tentative date for the event is between April 20 and April 30, but they are waiting to finalize the date based on your preference, if you are able to accept (even in early May). Please, let me know if you can accommodate t his additional engagement . You will make them very very happy! All the best, Paolo Paolo Lusso, M .D., Ph.D. Chief, Section of Vira l Pathogenesis Laboratory of lmmunoregulation Bldg. 10, Rm. 6All NIAID, NIH Bethesda, MD 20892 Phone: ...._ ___ Cb)(6) (personal) Cb _H_, 6) (lab) ________ Fax : (30 1) 480-5291 E-mail _. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Date: (b)(6) To: Subject: Wed, 8 Apr 2020 16:58:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: request of interview by Giuseppe Sarcina,corriere della Sera Let us discus s Begin forwarded message: From: Sarcina Giuseppe Date: April 8, 2020 at 4: 16:32 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6J: Subject: R: request of interview by Giuseppe Sarcina, corriere della Sera -------~= Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. I have sent an email march 21. But then I saw that you spoke with an other italian newspaper. So I would like to have a chance to have your voice for our Readers as well. Corriere della Sera is a newspaper based in Milano, Lombardy, The region most affected by the coronavirus. Thank you Warm Regards Giuseppe Sarcina Washington de (b)(6)> Oggetto: request of interview by GiuseppeSarcina,corriere della Sera Dear Doc. Fauci, this is Giuseppe Sarcina, the us correspondent of Corriere dell a Sera, the main italian newspaper. I understood that you are look ing at the italian case with great attention. I wonder if you can grant me a short interview. That would be really helpful for our readers Thank you Warm Regards Giuseppe Sarcina Washington de From: Date: (b)(6) Wed, 8 Apr 2020 16 :57:55 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Fwd: Global Healt h Leaders Call, Thursday , 8 April at 14:30 CET im age001.png , ATT0000l.htm, COVID19 Strategy Update V3 .2.docx, To: Subject: Attachments : ATT00002.htm Please print out for tomorrow. Thanks Begin forwarded messag e: From: "KABIR, Sophia" (b)( > Date: April 8, 2020 at 4:21:00 PM EDT To: SHOC , Office of the Director-Gen eral , "Redfield, Rober t R. (CDC/OD)' (b)(6) ---------- Heym ann (bH6l , >, David "Felicity Harvey (b)(6) (b)(6) "Chris. Elias" I>,"I.Farra r" 4 "Fauci , Anthony (b)(6) (NIH/NIAID) [E]" "GREIN , Thoma s" (bH6) , "COX, Paul Michael" "SCHW ARTLANDER, Bernhard F." (bH · , "MINHAS , (b)(6) Raman" (b)(6) ~, "MAHJOUR, "Conrad , Patricia (NIH/NIAID) [E]" (b) (6) , "Thoma s Jaouad" (b)(6) "FALL , fbrahima Soce" (b)(6) R. Frieden" (b)(6) , President I Resolve to Save Live s Lynn Bank s (b)(6) , -------------. ---------. "AL-SHORBAJI, Farah" Robynn Leidig "DRURY, Patrick Anthony" (b) < , "Dr VAN KERKHOVE,Maria" (b)(6) CbH6J , "POOLE, Marcia" Navarro Colorado (b)(6) "GRAAFF, Peter Jan" Cb)(6), Tarik Mohammed Cb)(6), Carlos (b)(6) , Ryan Morhard "BRIAND, Sy lvie" Cb)(6), "MORGAN , Oli ver" CbH "Han-ies, Jenny" CbH6),"Awwad, David (NIH/NIAI D) (C]" >, "SIMONSON , Stewart" CbH6), "SINGER, Peter Alexander" (b)(6) , "Jayatunga, Wik:um" ---------,, --------- (b)(6) "Julie.HALL" RIOUX (b)(6)> , "SHIN, Young-Soo" Cb)C6) Q! ·eng Ding (b)(6) ------------ "SMITH, Ian Michael" (b)( · , "AYLWARD, Raymond Bruce J." (b)(6) Cc: SHOC , Office of the Director-General , "SCHWARTLANDER, Bernhard F.",________ Cb><6J, "MAHJOUR, Jaouad" Cb><, "FAL L, Ibrahima Soce" (b)(6) , "GREIN, Tho mas'' CbH6)>, ~MINHAS, Raman" (b)(6) , "COX, Paul Michael" ...___ __,, (b)(6) , "AL-SHORBAJI, Farah" Cb)( "POOLE , Marcia" (b)(6) , "DRURY, Patrick Anthony" CbH6J , "GRAAFF, Peter Jan" Cb>< , "Dr VAN KERK.HOVE, Maria" Cb> <6J , "FARES, Christine Youssef'' (b)(6) ------- Subject: Global Health Leaders Call, Thursday, 8 April at 14:30 CET Dear colleagues, On behalf of M ike Ryan, allow me to share with you the dra ft COVID-19 Strategy Update, which will be subject of discussion at tomorrow's Global Health Leaders Call at 14.30 CET. The epidemiological update and analysis, as well as the Zoom connectionw ill be shared tomorrow morning. Please find below, the key questions for your consideration and input. l. What is your view on the latest epidemiology, virus transmission and severity in affected countries? 2. What are the emerging issues/challenges that you see as impo rta nt? 3 . What should be the priorit ies for the 1-2 weeks? 4 . Any other issues you see as important? If you experience any technical difficulties jo ining this confe rence call, please contact the WHO HQ EOCoperator at: +41 22 79 15 533 Kind regards, Sophia Sophia Kabir Executive Officer Office of the Executive Director WHO Health Emergencies Programme (WHE) Tel. (b) (6) Mobile ------ (b)(6) Website: WHO in emergencies I WHO Facebook I WHO Tw itter HEALTH EMERGENCIES programme From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 17 :28 :01 +0000 Awwad, David (NIH/NIAID) [C) FW: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Cert ificates Before They Expire Do I need t o do anyt hing? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496 -2263 FAX : (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and dele te it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: NIAID News and Information (NIH/NIAID) Date: Wed nesday, Apr il 8, 2020 10:18 AM To: NIAID Announcements Subject: NIAID Information RE: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) ---- -Original Message---- From: ORS Information Line Date: Tuesday, Apr il 7, 2020 6:23 PM To: NIH-STAFF@LIST.NIH.GOV Subject: Update Your PIV Card (HHS ID Badge) Certificates Before They Expire (b) (2) If you need help , please contact t he NIH IT Service Desk: http:// itservicedesk.nih.gov/ 301-496 -4357 (HELP). 301-496 -8294 (TTY), or 1-866-319-4357 (HELP) From: Fauci, Anthony (NIH/N IAID) [E) Date: Wed, 8 Apr 2020 17:25 :25 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patr icia (NIH/N IAID) [E];Stover, Kathy (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Doepel, Laurie (NIH/ NIAID) [E];Lane, Cliff (NIH/ NIAID) [E] Subject: RE:PR HHS Treatment Guidelines for COVID-19 We should include in the statement something about ----------- (b) (5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6J FAX: (301 496-4409 E-mail: (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Billet, Courtney (NIH/NIA ID) [E) CbH6J> Date: Wed nesday, April 8, 2020 12:58 PM To: Fauci, Anthony (NIH/NIAID) [E) CbH6J> Cc: Folkers, Greg (NIH/NIAID) [E] Cb H6J;Conrad, Patricia (NIH/ NIAID) [E] (b)( >; Stover, Kathy (NIH/NIAID) [E] (b)( >; Routh, Jenn ifer "':':"'."~""'.".""'."'.""'"':--:-:'.:";====-.;.._-_;_ --,;-,,~ (NIH/NIAID ) [E] (b)(6J;Doepel, Laurie (NIH/NIAID) [E] (b)( 6J Lane, Cliff (NIH/NIAID) [E) (b)( Subject; ASF: PRHHS Treatment Guidelines for COVID-19 ------~~ This is a press release t hat we (Laurie) drafted for HHS to announce the HHS treatment guidel ines. Cliff has revi ewed . I know how slammed you are. In the interest of time , I would like to move th is to Bill Hall now, with the understanding t hat we can catch up with any changes you might have before the release is actually issued. FYI, t he release includes a quote for you as follows: (b)( 5) (b)(5 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Wed, 8 Apr 2020 16:59 :29 +0000 Barillas, Carolina (NIH/NIAID) [El Holland, Steven (NIH/NIA ID) [El;Auchincloss, Hugh (NIH/NIAID) [El RE:Art icle - BCGprotect ion fr om COVID-19 mortality Than ks, Caro lina. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (3 96':44li9 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Alle rgy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [El Date: Wednesday, April 8, 2020 12:39 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Holland , Steven (NIH/NIAID) [El ..:=======:".:(b)(6} > ------~= (b)(6)> (b)(6)> (b"""" )(= ; Auchincloss , Hugh (NIH/NIAID) [El Subject: Article - BCG protection from COVID-19 mortality Hello everyone, I found this article that comes to a similar conclusion regarding the protective role of universal BCG vaccination on COVID-19 mort ality . I will be work ing with an epidemiologist from Virginia Tech to see if we can provide stronger quantitative analysis and modelling. All the best, Carolina Carolina Barillas Mury, M.D ., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Inst itutes of Health 12735 Tw inbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)(6) Fax:(301) 480 0930 E-mail: (b)(6) Fauci, Anthony {NIH/NIAID) [E] Wed, 8 Apr 2020 15:09:38 +0000 From: Date: To: (b)(6) FW: Google Alert - Fauci AND Tony OR Anthony Subject: Click on the "Cuomo Crush" and "Fauci Fever" link below. It will blow your mind. Our society is really totally nuts . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Google Alerts Date: Tuesday, April 7, 2020 11 :30 PM To: Fauci, Anthony (NIH/NIAID) [E] -----=(b)""(6J = > Subject: Google Alert - Fauci AND Tony OR Anthony Google Alerts Fauci AND Tony OR Anthony As-it-happens update Apri 8 2020 NEWS Dr. Anthon y Fauc L Trump address Iowa's lack of shelter-in-place Little Village Speaking at President Trump's press conference late Monday afternoon , Dr. Anthony Fauc i mentioned Iowa, and a clip of his comments was quick ly ... 11 CJ Flag as ,rrelev<'!nl Dr. Fauci: 'We need to put our foot on the accelerator' to see an end to COVID-19 pandemic fox4kc.com WASHINGTON - Even though he says the worst is yet to come. Dr. Anthony Fauci , the nation's top infectious-disease expert , has seen signs of ... Fl<'lQas Irrelevant 11 CJ Fauci: African-American Community at Higher Risk for Coronavirus Complications NBC4 Washington Dr. Anthony Fauci, director of the NIAID, spoke on Tuesday about the impact the coronav irus pandemic is having on the ... Read More ... John Calipari Confirms Bill Clinton. Mark Cuban. and Dr. Fauci as Guests on "Coffee With Cal" kentuckysportsradio.com Anthony Fauci. Every Monday for the next 25 weeks , Calipari's show will "feature positive messaging and conversation with high-profi le guests from the ... FlaQ as 1rrelev;int 11 CJ 'Cuomo Crush' and 'Fauci Fever' - Sexualization Of These Men Is a Real Thing on The Internet Talent Recap The coronavirus pandemic has led brothers Andrew and Chris Cuomo and Dr. Anthony Fauci to the forefront COVID news and updates, but it also ... 11 CJ FlaQ as ,rreJ.,v;mt Before the White House, Trump called NIH 'terrible,' questioned vaccines KPQ President Donald Trump speaks to the press wh ile Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci speaks during a ... 11 CJ Fla g as Irrelevant You have received this email because you have subscribed to Google Alerts. Unsubscribe ~Receive this alert as RSS feed Send Feedback From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 13:23:07 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:On the record Yes. Please point him to what I said ye sterday. Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Building 3 I , Room 7 A-03 31 Center Dri ve, MSC 2520 Nationa l Institutes of Health Bet hesda , MD 20892 -2520 Phone: (b) (6) FA X: (301 496-4409 E-mail: (b) (6) The informa tion in this e-ma il and any of its attachme nts is confidential and may contai n sensi tive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l Institute of Allergy and Infectio us Disease s (NlAI D) shall not accept liabili ty for any stateme nts made that are the send er's own and not express ly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/N IAID ) (E] Date: Wednesday , April 8, 2020 9:20 AM To: Fauci, Anthon y (NTH/NlAID) [E] Subject: FW : On the record ---------------=-::-=, -------- (b)( (b)( Pis see below ... .Bob Franken ... -----Original Message----From: Billet , Courtney (NJH/NTATD) [E] ______ Date: Wednesday , April 8, 2020 9:03 AM To: Co nrad , Patric ia (NTH/NJATD) [E Cc: Stover , Kathy (NIH/NIATD) [E] _______ (b) (6) Subject: RE: On the record ------~~ Cb _H_ > (b)(6) > Cb _)_(6) _ Routh, Jennife r (NIH/NIAID) [E] l think he probably knows Bob F ranken pe rso nally so I'm wonderin g if you might want to flag this for him, as he might decide it warra nts a personal respo nse. Otherwise, he did speak about health dispariti es at yesterday' s WH pre ss confer ence , and we cou ld certa inly poin t Frank en to those comm ents and then also direct him to NIMHD. ~ (b) (5) -----Original Message----From: Conrad, Patricia (NIH/N IAID) [E] (b)(6) Date: Wednesday, April 8, 2020 8:56 AM To: Billet, Courtney (NIH/NIAID ) [E] (b)(6) ? ; Stove r, Kathy (NIH/NIAID) [E] _______ Cb _H_6) Routh , Jennifer (NIH/NIAID) [E] (b) ( Cc: NlAlD OCGR NSWB Subject: FW : On the record ------ ~= Defer to you to decide on this ----- Original Message ----From: Bob Franke n _______ __,(b "')..., (=> Date: Wedne:sday , Apr il 8, 2020 5:17 AM ------ To: Fauci, Anthony (NIH/NIATD) [E]______ "="'~ (b _)_(6) _> Subject: On the record Tony : For my syndicated colunm, [ want to do a piece on the racial aspect of coronavirus. I'm not seeing any breakdown of deaths in the poorer areas as opposed to the more prosperous ones. Jsn 't that the telling statistic here that the economically less well off live in areas where medical services are inadequate and as a result they have more underlying conditions that make theM more vulnerable? Isn't it relevant that people of color are predominantly among the poorer in our country for a variety of reasons? 1 will appreciateyour comments, particularly since you have so little to do these days. Warmest regards, Bob Bob Franken www.bobfranken.tv (b)(6) From: Date: Wed, 8 Apr 2020 07:18:27 -0400 (b)(6) To: Subject: Re: last questions , i prom ise In first response , I mean t to say "I always qualified th e statement.. ..." .not "I almost qualified the statement. .." On Apr 8, 2020, at 7:04 AM , Michae l Specter Tha nk you . W ill do all this and take ou -------- --------- (bH6J >w rote: (b)(6) On Wed, Apr 8, 2020 at 03:59 Fauci, Anthony (NIH/NIAID) [E] (b)< >w rote: Michael: See comments be low in red. Th anks, To ny From: Michael Specter (b)(6) Date: Wednesday , April 8, 2020 1:25 AM -------~~ To: Fauc i, An thony (NIH/NIA ID) [E] _______ Subject: last questions, i promise (b_>_<6) Hi. Mostly these are two second yes or no answers - thou gh I need to understand the b cell issue better. Th ank you for all this . Hang in there: 1.) Fauci has at times struggled to compel politicians and businesses to attack the prob lems that he considers most woJTisome.Over the years, he has become especially concerned about the possible impact of a lethal strain of influenza." True, but I almost qualified the statementand said it most likely would be inJluenza, but I was concernedwith any type of novel respiratory virus that efficiently spread from human to human and that had a high degree of morbidityand mortality 2.) Dyker Heights versus Bensonhurst: • • What do we say about where he grew up.? He always says Bensonhurst. The apartment was technically in Dyker Heights, though the neighborhood lines shift. And I never see him mention moving neighborhoods. Did he move? Yes. I moved. I was born at (b) (6>. n the middle of the Bensonhurst section of Brooklyn. When I was 9 year s old my father opened a Pharmacy on 8302-13 th Avenue at the outer edge of the D yker Heights Section of Brooklyn (only We moved into an apartment over the pharmacy . • 3.) [ the question below is the meaning of hyperactive. Does it mean producing too many B cells or that they were too active, as in working too hard, producing too many antibodies??) Not necessarily too many B cells . It means that the B cells that are there, are aberrantly turned on He had been investigating B-cells, which are involved in the production of antibodies. In 1983-before H.l.V. was even known by that name-his lab became the first to report that B-cells becam e hyperactive in patients with AIDS. The virus was somehow leading its hosts to overproduce a defense that normally would keep them healthy. Fauci had ident ified one of the crucial features of AIDS. "We made that observation without having any idea of what we were dealing with," he said. "l think that speaks for sound scientific and clinical observation ." The pol itics of seeking a cure, though, would be far harder to manage. • 4.). This I asked before you could not speak to me but we can take me out of it. Or do whatever you like: I asked Fauci if he thought that novel coronavi rus would force a change in attitude among olitical lea ders and funding agencies . (b) (6)1 (b)(6) • 5.). This you lrnve sa id in rnore than one place. People kind of became alarmed when you were absent so ju st want to be sure you don't mind it in here: No problem . Fauci said that there was nothing meaningful about his absence from the Mar.23 White House briefing, "I was tied up in a task force meeting, and we were trying to work out some difficult policies and the topic of the briefing that day was more related to other members of the Task Force. He also said, '41have no troub le with the President. When .I talk to him, he listens.'' Michael Specter Staff Wri ter The New Yorker Adjunct Professor of Bioengineering Stanford University (b)(6) Phone: (Work, Cell , SMS) (b)(6) Michael Specter Staff Writer The New Yorker Adjunct Professor of Bioengineering Stanford Univers ity (b)(6) Phone: (Work, Cell, SMS) (b)(6) From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 10:42:24 +0000 Perez-Stable, Eliseo (NIH/NIMHD) [E] RE:WH Briefing To: Subject: Thanks, Eliseo. Stay safe and well. Best, Tony From: Perez-Stable, Eliseo (NIH/NIMHD) [E] ________ Se nt: Tuesday, April 7, 2020 11 :53 PM (b)(6) To: Fauci, Anthony (NIH/NIAID) [E) Subject: FW: WH Briefing _> Cb _<_·> -------- Hey Tony, you are the man! Best, Eliseo From: Natasha Williams -----------Date: Tuesday, April 7, 2020 at 8:42 PM To: Eliseo Perez Stable -------- (b ::-: )-'c (6) ,;;;> ---------- (b)(6) Cb)( >, Courtney Aklin Su bje ct : WH Briefing Hello Eliseo and Courtney, During the White House briefing on COVID-19this evening , there was a discussion on the disproportionate impact of COVID-19 on African Americans, health disparities and data collection. Please see CSPANClips below I cued up. https://www.c-span.org/video/?c4866877 /user-clip-covid-19-african-american-community https://www.c-span.org/video/?c4866892/user-clip-dr-fauci-hea1th-disparities-african-americancommunity https://www.c-span.org/video/?c4866897 community /user-clip-data-collection-guestion-african-american- I know we are not commenting but I would like to recommend that we have some ta lking points prepared and on hold in case we receive congressional inquiries. These topics are also receiving coverage on the networks . Thank you, Natasha Natasha H. Williams , PhD, JD, LLM, MPH Legislative Liaison National Institut e on Min o rity Healt h and Health Di s pariti es National Institutes of Health Bethesda, MD 20892 Email: Phone·. "';=== (b)(6) (b ~ )~ ~;;: 6);:-:1w -w - w-.n"".'i """':" m h°". d .. .n~ih.go-. Connect with us: Twitter I Facebook I YouTube I Email Updates NIMHD ---- .,._ --- From: Date: To: Cc: -----~~ EOP/WHO; _____ Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 8 Apr 2020 03 :06:30 +0000 Grogan, Joseph J. EOP/WHO Bonner, Maria K. EOP/WHO;Campana, Alexandra D. Cb _)_C6Jr _.;Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (N IH/NIAID) [E] RE: [EXTERNAL]RE: Good news Joe: I would be happy to speak with him. However, it wou ld have to wa it until Thursday since tomorrow is impossible. I bel ie ve that we can work this out. Perhaps we can arrange for a call between me ,the CEO and some knowledgeable people in my program. Best regards, Tony ----------- From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E]------ Cc: Bonner, Maria K. EOP/WHO ___ ___;____ _;__......:= (b)(6)'> (b =),-,(6) => ~(b~) ;; ( ai" >_______ (b)(l>l>; Campana, Alexandra _ D. EOP/WHO Subject: Fwd: [EXTERNAL)RE: Good news Dr., I would never abuse your personal email, but since the ceo of Lilly wants to speak with you, I thought I would share this request. Just let ------------------(b ::-: )-c(5=) me know how to respond -------------------- Sent from my iPhone Begin forwarded message: From: Shawn O'Neail Date: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, JosephJ. EOP/WHO" (b)(6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subject: [EXTERNAL) RE:Good news You bet. Joe - Have an enormous req uest-for help or counsel. (b) (4) My CEO,Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order-but underscores the importance. I did reach out to Dr. Fauci' s Chief but received an automated reply indicated he was behind in email - any though ts in the regard greatly appreciated .... Best, Shawn Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) (b) (6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confident ial and privileged information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ----------- From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------.!::::::==~ (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b::;: ) ~(6);---- Subject: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replying, clicking links, and opening attachments. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail (b)(6)> Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO ----------=-:--:-= EOP/WHO Subject: [EXTERNAL]Good news (b)(6)>; (b)( Bonner, Maria K. > Hi Joe and Maria I W> www .lilly.c om « ---------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review. use. disclosure. copying or distribution is strictly prohibited. If you are not the intended recipient. please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 02 :41 :56 +0000 To: (b)(6) Subject: FW: [EXTERNAL]RE:Good news Cliff: let us discuss this. How do you think that I should respond? Thanks, Tony -----------------~~ From: Grogan , Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 10:19 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Bonner, Maria K. EOP/WHO ___ (b) (6), CbH6)> .;...;;.::::::========---::-:~ (b)( ; Campana, Alexandra D. EOP/WHO _:_ ____ .:,__..!::::=-- (b=--= )~ (6)-::-------- Subject: Fwd: [EXTERNAL]RE:Good news Dr., I wou ld never abuse your perso na l email, bu t since the ceo of Lillywants to speak with you, I thought I would share this request . Just let me know how to respond , ------------------(b =--: )--: (= 5) Sent from my iPhone Begin forwarded message: From: Shawn O'Nea il Dat e: April 7, 2020 at 10:07:37 PM EDT To: "Grogan, Joseph J. EOP/WHO" (b) (6) --------~~ (b)( 6) ---------- (b)(6)> , "Bonner, Maria K. EOP/WHO" Subj ect: [EXTERNA L) RE: Goo d news You bet. Joe - Have an enormous req uest -for help or co un sel. (b)(4) My CEO, Dave Ricks, would like to speak with Dr. Fauci in th is regard (given his role at the Institute). I know t hat is a tall order - but underscores the importance . I did reach out to Dr. Fauci's Chief but received an automated reply indicated he was behind in email - any thoughts in the regard greatly appreciated .... Best, Shawn ------------------------------------------------- Shawn O'Neail Vice President, Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mob ile) (b)(6) I >www.lilly.com< --------- CONFIDENTIALITY NOTICE: This e-mail message (including all attachments) is for the sole use of the intended recipient(s)and may contain confidentialand privileged information. Any unauthorized review, use, disclosure, copying or distributionis strictly prohibited.If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. ------------ From: Grogan, Joseph J. EOP/WHO Date: Tuesday, April 7, 2020 9:31 AM To: Shawn O'Neail ------=== (b)(6) (b) (6)> Bonner, Maria K. EOP/WHO (b ="" )='c' (6) ::;;----- Subje ct: [EXTERNAL]RE: Good news EXTERNAL EMAIL : Use caution before replyin g, clicking links, and ope ning attachm ents. This is great. Thank you for sharing and everything you are doing. Joe From: Shawn O'Neail Date: Tuesday, April 7, 2020 9:26 AM To: Grogan, Joseph J. EOP/WHO EOP/WHO Subje ct: [EXTERNAL]Good news (b) (6) ---------(b)( --,;= (b)(6) Bonner, Maria K. > Hi Joe and Maria I want to share an important update about Lilly's efforts to address insulin affordability. In response to the cr isis caused by COVID-19, Lilly is int roducing the Lilly Insulin Value Program, allowing anyone with commercia l insurance - and those w ithout insurance - to fill their monthly prescription of Lilly insulin for $35 . The program is effective today and covers most Lilly insulins . Details and more information can be found in the press release here attached . Lilly has introduced severa l solutions in recent years to help meet the individual financial circumstances of people living with diabetes that are still in effect during the COVID-19 crisis, including: • The Lilly Diabetes Solution Center, throu gh which representatives can direct people to the $35 savings card, as well as affordability options that may reduce their out-of-pocke t costs further - such as free insulin for people with minimal income, or no income at all, that has been donated by Lilly to non-profit organizations. • Three non-branded versions of our insulin options with list prices 50 percent lower than the branded versions. • In January, the company announced plans to donat e at least 200,000 KwikPens ® to relief agencies over the next three years. Hope all is well with you .... Shawn ------------------------------------------------- Shawn O'Neail Vice President , Government Affairs Eli Lilly and Company (b)(6) (office) I (b)(6) (mobile) Cb)(6) I »www .lilly.com« --------- CONFIDENTIALITY NOTICE : This e-mail message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review , use, disclosure , copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message. From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 22:58:33 +0000 Chris Joffe ;Fauci, Anthony (NIH/NIAID) [El RE:Supporting Schools In Covid-19 Due to the high demand on Dr. Fauci's time during th e current outbreak -we must decline your request at this time. Thank you for your understanding . Best, Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institut e of Allergy and Infectious Diseases The National lnstitues of Health (b)(6) (office) (b)(6) (cell) ===;;::,=:~ ----- From: Chris Joffe Date: Tuesday, April 7, 2020 6:46 PM ------~= To: Fauci, Anthony (NIH/NIAID) [El Subject: Support ing Schools In Covid-19 (b)(6) Dr . Fauci I'm a safety/security consultan t to independen t and charter schoo ls. I run a firm supporting ~ 1,000 of them. What, if anything , would you wan tth ern to know? I'm wondering if there's any chance in the world you'd be willing to join us and a few hundred schools for a 15 - 30minute webinar one day next week? Specifically , schools are looking for infom1ation /perspectiv e as it relates to what to expec t as we return to a new normal and the like. Beyond that , they've begun to ask questions such as what we can be thinkin g about for this short period of time between the return to schoo l and the development of a vaccine. What would best prac tic e look like for us to educate, but maintain social distance ? I believe we can manage a lot of th e operationalizing but would be immensely grateful for some h igh-level guidance to follow . I recognize how incredibly busy this time is for you and would be so incredibly grateful for any time you might be willing to spare for this audience . With imm ense gratitude, Chris Joffe Chris Joffe CEO I Joffe Emergency Services HQ I Santa Monic a, CA Twitter : @joffec hris (b)(6) Executive Assistant E: P: (b)(6) Cb H6> From: Date: (b)(6) Tue, 7 Apr 2020 13:12:39 -0400 Lane, Cliff (NIH/NIAID) [E] Fwd: To: ~-------------------------- (b)(4) (b)(4) Here it is Begin forwarded message: ___________ __, (b) (6)l From: "Gelfand , Jeffrey A.,M.D." Date: April 7, 2020 at 9:39:5 1 AM EDT To: "Callahan , Michael Y.,M.D." ________ ------------~~ "Fauci, Anthony Subject: IH/NIAID E " (b)(__,', (b)( (b) (4) From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 7 Apr 2020 15:45:18 +0000 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/ NIAID) [El RE:NFLPA-NFLTask Force (b) (5) Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] ________ (b_H _ > Date: Tuesday, April 7, 2020 11:09 AM To: Fauci, Anthony (NIH/NIAID) [El______ Subject: FW: NFLPA-NFL Task Force (b_H_6) (b) (5) Pis see below - -------- From: Billet, Courtney (NIH/NIAID) [E] Date: Saturday, Apr il 4, 2020 12:06 PM To: Conrad, Patricia (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E]_______ ------- (b) (6)> ~= > ;......:.=======~~Auchincloss, Hugh (NIH/N IAID) [E] (bH (b_H_6)>; (b)(6)> Subject: RE: NFLPA-NFLTask Force (b) (5) From: Date: Saturday, Apr il 4, 2020 11:01 AM -------------------- (b)(6) To: Billet, Courtney {NIH/NIAID) [E] Cc: Thom Mayer _________ (b)(6)> Cb _>_C_ > Subject: NFLPA-NFLTask Force Hi Courtney, 15 \ I hope you, you r family and your loved ones are harboring safely through this storm . 2 nd , t hanks for your efforts and those of Dr. Fauci-he is truly a national treasure during this crisis and it is deeply appreciated. I appreciate your help and introductions on how our players can be helpful. As you know Drew and Brittany Brees made a $SM contribution to the Louisiana coronavirus efforts and they have done a lot of press. Drew's message has been "Hang in there-hang tough I We are in th is t ogether." I've done several webinars with our players and their fami lies, both educating them and pointing out thei r role both with friends and fam ily as well as on social media to let NFLfans know that whether or not we have an NFLseason depends to a large extent upon those fans following the guidelines zealously-as zealously as they follow NFLgames! That message seems to be getting through . I write now with a request for a litt le bit of Dr. Fauci's time in about 2 weeks. I requested that we stand up a joint NFLPA-NFL Task Force to scenario plan a pathway to getting NFLClub facilities open, with a view towards if and when we might look towards an NFL season, even if games are played with no fans. My request is to have Dr. Fauci give a telephone briefing to our group on this difficult topic, which would of course be confidential. The floor would be his and I can brief him prior to the call on what we have been working on. If he were willing, w e can do the call anytime, probably during the week of April 13, although of course the modeling shows that would be during the peak of the outbreak. We could also do it the week befo re or after. Thanks so much fo r conside ring this . We are mindful of the psychological toll the virus is taking and the lift NFL games would give to a sports-starved population, but only if it can be done safely for the players and the fans who (ultimately) allow them to play this great game. Again, thanks! Best, Doc Thom Mayer, MD, FACEP, FAAP, FACHE Medical Director ■ NFLPA NFL Players Association 11150 Sunset Hills Road, Ste 305 Reston. VA 20190 ----- Mobile: NFLPA .COM (b)( From: Date: To: Cc: [E] ----~ Subject: Fauci, Anthony (NIH/N IAID) [El Tue, 7 Apr 2020 15:24:35 +0000 Barillas, Carolina (NIH/ NIAID) [ El Ho lland, Steven (NIH/NIA ID) [E];Auchincloss, Hugh (NIH/NIAID) (b~ )(6) = RE: BCGprotect ion from COVID-19 mortal ity Caroli na: (b) (5) Best regar ds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bari llas, Carolina (NIH/NIAID) [E] Date: Tuesday, April 7, 202011 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Holland , Steven (NIH/N IAID) [E] ________ ------ (b)( > ::;..,..-,= (b)( 6J> _'";::=======-=~ Cb _H_6); Auchincloss, Hugh (NIH/NIAID) [E] (b) (6) > Subject: BCGprotec t ion from COVID- 19 morta lity Good mornin g Tony, (b) (5) All t he bes t, Carolina Carolina Barillas Mury, M.D., Ph.D. Chief, Mosquito Immunity and Vector Competence Section Laboratory of Malaria and Vector Research National Institutes of Health 12735 Twinbrook Parkway, Room 2E-20C Rockville, MD 20852 Phone: (b)( Fax: (301) 480 0930 E-mail (b) (6) Fauci, Anthony (NIH/N IA ID) [E) Tue, 7 Apr 2020 14:51:59 +0000 To: Alison Galvan i Subject: RE:Your PNAS articl e " Projecting hospita l utilizat ion during the COVID-19 outbr eaks in the United States" has published From: Date: Alison: Thanks for sending this. I hope that all is well with you. Keep up your great work. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAIDby one of its representatives. From: Alison Galvani (b)(6) Date: Friday, April 3, 2020 3 :34 PM To: Fauci, Anthony (NIH/NIAID) [E] -------,;-, Cc: Conrad, Patricia (NIH/NIAID) [E) ---------Subject: (b)""'c= ,> (b)(6) •>; Singer,Burton H (b)(6) ; Seyed Mo ghadas (b)(6) Fwd: Your PNASarticle "Projecting hospital uti lization during the COVID-19 outbreaks in the United Stat es" has published Hi Tony , Please find attached our second COVID publ ication. This one focuses on projections of the number of ICU beds that will be needed at the peak of the outbreak. Please don't hesitate to let me know ifwe can be of any assistance. Take care, Aliso n ---------- Forwarded message --------From: Date: Fri, Apr 3, 2020 at 2:06 PM Subject: Your PNASarticle "Projecting hospital utilization during the COVI0-19 outbreaks in the United States" has published (b)(6) To: ---------- PNASis pleased to announce t hat your paper "Projecting hospital utilization dur ing the COVID-19 outb reaks in the United Sta tes " has published on line at: www .pnas.org. Did you know article-level metrics dat a and article downloads are now available for all PNASart icles? Article-level metrics provide a new way of measuring the reac h and impact of an article by tracking the ment ions it receives on line. Clicking on the "Authors & Info" tab near t he top of each article and scrolling down w ill reveal a summary of ment ions of the article across news sites, biogs, social media, and other on line sourceswh ich are visualized in a colorful icon, or "badge." The number in the m iddle of the badge is the Altmetric score, wh ich is based on the volume , type, and author of the mentions. You can click on the badge or "view more" to explore th e indiv idua l mentions from each source. Art icle down loads by month and by article format appear below the badge. Stay connected to PNAS: Follow Us on Twitter Find Us on Facebook Aliso n Galvan i, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven. CT 06520 (b)(6) http:ljcidma.yale.edu/ Follow me at @Alison_ Galvani Follow CIDMA @YCIDMA From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 14:47:59 +0000 Glass, Roger (NIH/FIC) [El RE:To cheer you up! Than ks, Roger ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------------- =-:--:= From: Glass, Roger (NIH/ FIC) [El Se nt: Friday, April 3, 2020 12:36 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: To chee r you up ! (b)(6)> (b)(6) Tony Read the last lines and see the photo! Your words from the past are remembered and have changed the caree rs of our fellows. No need to respond . Roger Sent from my iPad Begin forwarded message: From: (b)(6) Date: April 3, 2020 at 11:30 :23 AM CDT To: "Glass, Roger (NIH/Fie) [E)" _____ Subj ect: Hello Dr. Glass, ""(bes"' ~= c > I hope you are well and I wanted to check in to see how you are doing in this scary and traumatic time for our world. During these times, I'm especially thankful for the training I received from the Fogarty Institute. I remember your wise words at our Fogarty orientation in 2011- on why investing in Global health is so critical. No truer words have been spoken especially at times like these! I'm currently communicating with my former colleagues in Zambia (Mpanji and Innocent pictured here with me https ://www.thermofisher.com/blog/behi ndt hebench/ using-sanger-seq uen cing-to detect-d rug-resistance-m utations-i n-h iv-i n-zam b ia/) from CIDRZ to see how testing can be brought up via the public health infrastructure in place currently. Thankfully, the number of cases is very low, although the unreported cases are much higher than likely captured ( https://www .arcgis.com/apps/opsdashboard/index .html#/bda7594740 f d402994 23467b4 My friend who is a Lieutenant Physician actually likely contracted COVID-19 in January and wrote that she and others had treated a patient returning from Wuhan who was pregnant of respiratory illness upon coming back to Lusaka to deliver, only to die of pleural effusion later. They subsequently developed flu-like symptoms and resolved, but these are the types of cases that likely go undetected and can potentially contribute to community spread of the disease . 8e9ecf6 ) . Thank you again for being such a wonderful role model, and I look to leaders like you and Dr. Fauci to help our nation think with prudent but difficult decisions . Kind regards, Lillian ase Th, at Implementation: Delivery o Proven Interventions to Patients and Populations From: Date: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14 :44:25 +0000 (b)(6) To: (b) (4) (b) (4) What do yo u thin k of this stud y? Anthony S. Fauci, MD Direc; tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gelfand, Jeffrey A.,M .D. Se nt: Tuesday, April 7, 2020 9:39 AM To: Callahan, Michael V.,M.D. (b) (6)> ----------___________ ...... ---------- -,;-,-.,= (b)(6J>; Fauci, Anthony {N IH/NIAID) [E] (b)(6)> (b) (4) Importanc e: High Dear Tony and Michael: (b) (4) (b) (4) Mark Poznansky Vaccine and Immunotherapy Center Division of Infectious Diseases Massachusetts General Hospital CbH6) ( ------ C)-J e ff Cb> <6)- M ark From: Chen, Huabiao, M.D . Se nt : Monday, April 6, 2020 9:07 PM To: Gelfand, Jeffrey A.,M.D. ___ __;,__ .:_..:..,____;~~ (b ~)~(6) ~------ (b)(6) ----------,;-;~ CbH6)>;Poznansky, Mark,M.B.,Ch.8.,Ph.D . (b) (4) Dear Jeff and Mark, (b) (4) Thanks, Huabiao ------------ From: Chen, Huabiao, M .D. Date: Monday, April 6, 2020 12:41 PM To: Gelfand, Jeffrey A.,M .D. Subjec t : Re: --------~~ (b)(6) (b)(6)> ====-------------------------- (b) (4) attached please find the supporting information in PDF From: Chen, Huabiao, M .D. Se nt : Monday, April 6, 2020 12:23 PM To: Gelfand, Jeffrey A.,M. Subject: Re: (b)(6)> ----------- ---------- If needed please download the supporting == (b)(6) (b) (4) information ------------------~~ From: Gelfand, Jeffrey A.,M .D. Date: Monday, April 6, 2020 12:16 PM To: Chen, Huabiao, M .D. ------------ ------------- (b)(6)> CbH6)> (b) (4) (b) (4) Wow! Reading it now ...Jeff ------------ From: Chen, Huabiao, M.D. Date: Monday, Apri l 6, 2020 11:46 AM To: Gelfand, Jeffrey A.,M.D. Subject: _______________________________ - (b)(6) ---------.. = -'="':========~ (b)(6b (b_H_4) Importance:High Dear Jeff, I had a Chance getting this information fro m. (b)( 6)j Dr. Danlei Mou who works very diligently and seriously on this clinical study. You may be interested in this primary information. Please keep it confidential. Best, Huabiao The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mai l was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 11 Apr 2020 23:21 :25 +0000 Upton, Fred RE:GOP lawmakers: Fauci may be doing more harm than good To: Subject: I TheHill Thanks, Fred. I appreciate your note. Best rega rds , Tony _____ -----Original Messa,...,_ e----From: Upton , Fred ..,,.,.~ (b)(6) > Date: Saturday, April 11, 2020 6:31 PM To: Fauci. Anthony (NTHINIAID)[E] -------~~ (b)( Subject: Re: GOP lawmakers: Fauci may be doing more hann than good I TheHill Up date. Biggs and Buck are the only 2 memb ers of Congress that vote d agn the first two bills dea ling with COVID -19. The first vote had only the 2 of them vote no. NRN Sent from my iPhone -------- > On Apr 11, 2020, at 5:45 PM, Upton, Fred (b)(6) wrote: > > It's upton again and no need to respond. U may get asked about this story and u sho uld know that both Buck and Biggs were among the 40 that vote d no on the 2nd package which provided assistance and testing (think it was $ 13B). It was not a surprise that they voted no as they r joined with Tom Massie in almost everything. Keep being a science tn1th teller□ C > http s://thehi 11.com /homen ews/ corona virm-report/ 4923 5 9-gop- lawmakers- fauci-may-be-doin g-more-harm-thangood > > > Sent from my iPhone From: Date: Fauci,Anthony (NIH/NIAID) [E) Sat, 11 Apr 2020 19:26 :02 +0000 Upton, Fred RE:It's Fred upton To: Subject: Fred: Thanks for the note. The answer is almost certai11lyyes, but there wou ld not be enough of them whereby we can compare the results in those who were rece iving Hydroxychloroquine or not for their lupus. Large natural history studies, which we will be initiating could possibly answer that question. Best regards, Tony Anthony S. Fauci. MD Director National Institute of Allergy and InfectiousDiseases Building 31, Room 7A-03 3 I Center Drive, MSC 2520 National Jnslirutes of Health Bethesda, MD 20892 -2520 Phone: (b)(6) FA X: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National 1nstitute of Allergy and Infectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----OriginalMessage----From: Upton, Fred Date: Friday, April l 0, 2020 6:0 l AM To: Fauci, Anthony (NIH/NlAlD) [E) Subject: It's Fred upton ~------~~ (b)(6) --------=-,...,.= --------(b)(6) > U gave me your email at the Capitol briefing. Question, with all the discussion on hydrox.- have there been any Covid- J9 cases that have stmck.lupus victims? TY Sent from my iPhone From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 15 Apr 2020 22:29:20 +0000 Bergmann, Kenneth Lerner, Andrea (NIH/NIAID) [El RE: a thought on selective vulnerability to SARS-CoV-2 Thanks, Ken. Interesting concept. I will run it by our program people. From: Bergmann, Kenneth ___________ Cb _>_<6>i> Date: Wednesday, April 15, 2020 4:55 PM To: Fauci,Anthony {NIH/NIAID) [E] -----(b =)""'(6) => Subject: RE: a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found useful. Hope you are not sorry you asked... © (b) (5) (b) (5) Best regards, Ken (b) ( > From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6) Subject: RE: a thought on selective vu lnerab ility to SARS-CoV-2 ------------------~~ Ken: I have thought about the same or similar issues. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used bv anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)( > Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] ------= (b-s--r H=6) Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA View point of February 25. (b) (6). (b) (5) Thank you for all you do. Sincerely Ken Kenneth J . Bergmann, MD, FAAN Sen ior Medical Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993-0002 Office: (b) (6) Mobile: ) §) Email.._ _______ _._,,.:(,:;,., © Fauci, Anthony (NIH/NIAID) [El Wed, 15 Apr 2020 22:28:57 +0000 To: Lerner, Andrea (NIH/N IAID) [El Subject: FW: a thought on selective vulnerability to SARS-CoV-2 Attachments : l_Mab induced Cytoki ne Storm NEJM 2006.pdf , 2_Covid_pregnancy.pdf, 3_ Neon ate _i nnate _im mun ity _2018.pdf, 4_nihms832701.pdf, 5_ 12948_2017 _Article_77.pdf From: Date: Please check th is out with program people. Thanks. From: Bergmann, Kenneth (b)( > Date: Wednesday, April 15, 2020 4:55 PM ~= To: Fauci, Anthony (NIH/NIAID) (E]-----(b)(6)> Subject: RE:a thought on selective vulnerab ility to SARS-CoV-2 Hi, Tony This is not my field but I had some ideas, so thank you for indulging me in thinking about "why not kids." I attached citations I found usefu l. Ho pe you are not sorry you asked ... © (b) (5) (b) (5) Best regards , Ken From: Fauci, Anthony (NIH/NIAID) [E] (b)( > Date: Tuesday, April 07, 2020 9:50 AM To: Bergmann, Kenneth (b)(6)> Subject: RE: a thought on selective vu lnerab ilit y to SARS-CoV-2 ---------- Ken : Thanks for the note. "=""= I have thought about the same or similar issues. Best regard s, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Bergmann, Kenneth (b)(6) Date: Saturday, Apr il 4, 2020 9:39 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)""'(6J = > Subject: a thought on selective vulnerabil ity to SARS-CoV-2 Dear Dr. Fauci I read with interest your JAMA Viewpo int of February 25. (b) (6), (b) (5) Thank you for all you do. Sincerely Ken Kenneth J. Bergmann, MD, FAAN Senior Medica l Officer Division of Neurology I. Office of Neuroscience Center for Drug Evaluation and Research U.S. Food and Drug Administration Building 22, Room 4143 10903 New Hampshire Avenue, Silver Spring, MD 20993 -0002 Office: (b) (6) Mobile: > §) Email: .__ ______ __."'-' @ = From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 12 Apr 2020 22:44:30 +0000 Marston, Hilary {NIH/NIAID) [E) FW: Collection of COVID-19 patient data from medical records Please take a look at this and figure out whether we should do something. From: Hahn, Stephen (b)( Se nt : Thursday, March 26, 2020 5:40 PM To: Fauci, Anthony {NIH/NIAID) [E] (bH ; Debi Birx Cc: Abernethy, Amy (FDA/OC) > ------~= ------ _.:....:...:.=:=====-~ (b)(6)>; Redfield, Robert R. {CDC/OD) (b)(6)> (b)( >; Lenihan, Keagan (FDA/OC) (b)(6) Subject: Collection of COVID-19 patient data from medical records Tony, Bob and Debi, Amy is working on a pathway to collect data from electronic medical records in selected areas of the country (addressing all of the appropriate privacy concerns) . We're looking for data elements to collect and wonder if your teams could give us some insight from a public health perspective. I am copying Amy to see if she has anything else to add. Perhaps you could assign someone to wo rk with Amy. Thanks Steve From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Sat, 18 Apr 2020 18:55:23 +0000 Kamoie, Brian RE:Thank You Thanks, Brian. I appr eciate your not e . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------::-::-:-= From: Kamoie, Brian Date: Saturday, Apr il 18, 2020 12:33 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank You (b)( -------- > (b)( > Tony, Thank you for all that you are doing in the fight against COVID-19. Your steady leadersh ip and groundi ng in the science, and your ability to communicate comp lex informat ion clear ly to policymakers and the public, are what the wor ld needs during this crisis. I know we will see the other side of th is pandem ic, and you will have once again saved many lives with your wor k. I am one step removed from this response, as I am on a deta il assignment from FEMA to the Naval Academy, but have been sharing information with the Superinten dent and his senior leader ship team so t hat t hey can make good decisions to protect the community w hil e meet ing the Academy's mission. I have thought back to th e H1N1 response in 2009-2010 many t imes since th is began. Again, t hank you for what you're do ing. My best wishes to you and your family . Best, Brian (b)(S) - PCR (bXS) - PCB From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 16 Apr 2020 03:00:26 +0000 To: Collins, Francis (NIH/OD) [El;Myles, Renate (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El;Wo linetz , Carrie (NIH/OD ) [El;Lane, Cliff (NIH/NIAID) [El Cc: Burklow, John (NIH/OD) [E];Fine, Amanda (NIH/OD) [El;Wojtowicz, Emma (NIH/OD) [El;Fritz, Craig (NIH/OD ) [El ;Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Ditto. ------- (b)(6) From: Collins, Francis (NIH/OD) [E] Date: Wednesday, April 15, 2020 10:57 PM To: Myles, Renate {NIH/OD) [El Cb)( >; Tabak, Lawrence {NIH/OD ) [El (b)( >; Woli netz, Carrie (NIH/OD) [El (b)( ; Fauci, Anthony ":'---:---'"""".""'."""':'====-.:----=~ (NIH/NIAID) [El (b)(6) >; Lane, Cliff (NIH/NIAID) [El (b)(6) Cc: Burklow, John (NIH/OD) [E] (b)(6) Fine, Amanda (NIH/OD) [El (b)( ; Wojtowicz, Emma (NIH/OD) [El (b)(6); Fritz, Craig (NIH/OD) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [El CbH6J>;Stover , Kathy (NIH/NIAID) [El (b)(6J>; Routh, Jennifer (NIH/NIA ID) [El -----~~=====-=--_;,_.~ _ _;_..;._ __ _;__;_(b ~ )~(6) =-> ------- Subject: RE: For review tonight: draft Sec. Azar statement on ACTIV Looks generally OK FC From: Myles, Renate (NIH/OD) [El Date: Wednesday, April 15, 2020 10:44 PM To: Collins, Francis (NIH/OD) [El -------- CbH > CbH6J>; Tabak, Lawrence (NIH/OD) [E] >; Wolinetz, Carrie (NIH/OD) [El (b)( >; Fauci, Anthony CbH6J>; Lane, Cliff (NIH/NIAID) [E] (b)(6) ------~===::!....:. __ ,---;. (NIH/NIAID) [El (b)( Cc: Burklow, John (NIH/OD) [El CbH6J;Fine, Amanda (NIH/OD) [El (b)(6)>; Wojtowicz, Emma (NIH/OD) [El (b)(6)>; Fritz, Craig ":'--:-:-:-::-:-:-:::-:===:;_;_~= (NIH/OD) [El (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6) 1>; Stover, Kathy (NIH/NIAID) [El (b)(6)>; Routh, Jennifer {NIH/NIAID) [El (b)(6) Subject: FW: For review tonig ht: draft Sec. Azar statement on ACTIV Importance: High --.-~:=====-.;__~ ~ Good evening : I'm sending this direct ly to principals given the quick turnaround. I've let ASPA know that the goal is to issue the release sometime tomorrow . Thanks, Renate ---------- From: Brennan, Patrick (OS/ASPA) Date: Wednesday, April 15, 2020 10:20 PM To: Burklow, John (NIH/OD) [El ------~~ (b)(6) -------- Cb)( >; Fritz, Craig (NIH/OD) [El Cb)( ; Myles, Renate (NIH/OD) [El (b)(6 b; Fine, Amanda (NIH/OD) [El (b)(6 b ; Wojtowicz , Emma (NIH/OD) [El (b)(6 h; Akinso, Woleo la (NIH/OD) [El (b)(6h; Stimson, Brian (HHS/OGC) CbH >; Charrow, Robert (HHS/OGC) (b)(6)> Cc: Mu rph y, Ryan (OS/ASPA) (b)(6 b; Pratt, Michael (OS/ASPA) (b)(6 h; Oakley, Caitlin B. (05/ASPA) (b)(6)> Subject: For review tonight : draft Sec. Azar statement on ACTIV --.-".'""'."'~==::::::!!;...;.._ :....,,= -:--"".";:======~ ~ --------- NIH and OGC, Can you let me know if the below and attached statement from the Secretary looks OK? Assumin g it is going tonight from NIH, approv al as soon as possible would be great. Thank you! - Patrick (b)(5) Pat rick Brenna n Director of Speechwr iting Department of Health and Human Services Office: (b) (6) I Cell: (b) (6) Fauci,Anthony {NIH/NIAID) [E) Mon, 13 Apr 2020 01:14:17 +0000 Mascola,John (NIH/VRC)[E) Erbelding, Emily (NIH/NIAID) [E);'Dieffenbach, Carl (NIH/NIAID) [E]' ;Marston, From: Date: To: Cc: Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: FW: Pursuant to My Email on Frida y Attachments: Vaccine strategy-200411-v 13.pptx, Secretary Determination MemorandumProject Warp Speed-041120 1825 draft .d oc John: Let us br iefly discuss this tomorrow AM . (b) (5) Best, Tony --------- From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, April 12, 2020 8:59 PM To: Hassell, David (Chris) (OS/ASPR/10) ___ _;_ _ __; _ __;_.;._.;.__,;__,;.:::::====== (b) (6)> CbH6);Collins, Francis (NIH/OD) [El Cb ::;; >::;, <6) 5i"":'"' Mascola, John (N IH/VRC) [El Bright , Rick (OS/ASPR/BARDA) CbH6) ; Fauci, (b)( >; Disbrow, Gary {OS/ASPR/BARDA) (b)( ; Patrick, Vanessa (OS/ASPR/BARDA) (CTR) CbH6)>; Moughalian, Jen {HHS/ASFR) CbH Redfie Id, Robert R. (CDC/OD) CbH >; Messonnier, Nancy (CDC/DDID/NCIRD/0D) CbH ; Lane, Cliff (N IH/NIAID) IE] CbH6)>;Marks, Peter (FDA/CSER) CbH6)>; Yeskey, Kevin (OS/ASPR/10) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Dareshori, Zack {HHS/10S) (b)( (b)(6)>; Conrad, Patricia (NIH/ NIAID) [E] Stecker, Judy (OS/10S) CbH6)Shuy, Bryan (OS/ASPR/10) (b) (6) > CbH6)>;Wolinetz, Carrie (NIH/OD) [El Subject: Pursuant to My Email on Friday (b)(6),; Anthony {NIH/NIAID) [E] ========-~ ---------- ----------:a- = ======::::::.;_~= ---------- -------- ------------------- I want to share with you the product of the BCGteam who drafted the attached briefing and Decision Memo drafted for the Secretary's review t omorrow. I want to thank all those who contributed over this holiday weekend to offer their ideas and concepts that is represented in t hese products. Th is represents just a first step of many steps that first outlines a concept that will then be operationalized into a histor ic effort for not only the Department and agencies who will contribute to it, but to our Nation. Again, thank you for your contributions and commitment. Best Bob From: Fauci, Anthony (NIH/NIAID) [E) Date: Mon, 13 Apr 2020 00:32:55 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIA ID) [E];Conrad, Patricia (NIH/N IAID) [E];Routh, Jennifer (NIH/NIAID) [E];Mar ston, Hilary (NIH/NIAID) [E] Subje ct : RE:daily data call from Sec Ofc Th is looks rea lly good. Th anks. From: Billet, Courtney (NI H/N IAID) [E) (b)(6) Date: Sunday, Apr il 12, 2020 7 :27 PM To: Fauci, Anthony (NIH/ NIAID) [E] (bH6>r> Cc: Folkers, Greg (NIH/NIAID) [E] (b)( ---------=-:-:-= >; Conrad, Patr icia (NI H/N IA ID) [E] Routh, Jennifer (N IH/NIAID) [E] Hilary (NIH/NIA ID) [E] (b)(6l --------Marston, (bH6)>; (b)(6b; Subject: ASF: dai ly data call from Sec Ofc Per request from the Secretary's office that I sent you this morning, below is what I propose to submit tomorrow morning for the new daily 9am data call. I wil l plan to submit pretty much the same thing every day. I will not Glog your in-box with it unless there is a significant update. RFI from Staff Sec: 1. For tomorrow's press conference , what information or topics do you recommend be included in the President's remarks? Please provide talking point-level details and support. Nothing specific from NIAID at this time. 2. For tomorrow's press conference , on what information (if any) do you intend to speak? SpeGific topics will depend on questions from reporters. Dr. Fauci has been asked about the effect of social distancing; considerations that would facto r into returning the country to normal life; off-labe l use of treatments such as hydrochloroquine ; the status of clinical trials ; and the disproportionate impact of COV ID-19 on communities of color. NIAID-specif ic talking points: • NIAID has mobilized a rapid research response to quickly develop effective countermeasures for COVID-19, including diagnost ics, vaccines to prevent disease and treatments. • NIAID is supporting a clinical trial of the antiviral remdesivir and is investigating other treatments , including antibody therapies and other antivirals , for their activity against SARS-CoV-2 . Well-designed clinical trials are the best way to evaluate potential treatments for safety and efficacy . • NIAID is supporting an early-stage clinical trial of an investigational vaccine called mRNA - 1273, developed by NIAID scientists and the biotechnology company Moderna. The study launched first in Seattle, with a second site recently added in Atlanta . NIAID is researching additional vaccine candidates. • NIAID has launched a serosurvey study that aims to determine how many adults in the United States without a confirmed history of COVID-19 have antibodies to the virus . Researchers will collect and analyze blood samp les from as many as 10,000 adu lt volunteers without a confirmed history of COV ID-19 . The results will help illumina te the extent to which the novel coronavirus has spread undetected in the United States and provide insights into which communities and populations are most affected. [NOTE : Thi s serosurvey is for research purposes. It is not meant to be a way fo r people to access antibody testing for personal knowledge of prior infection history. If it is portrayed as a way for people to "get tested " to understand their own infection history , we can expect that peop le will inaccurately blame the government for not rece iving results in a timely manner . People can request to learn about their results, which will be available only after weeks or months of analysis.] • NIAID is expanding its portfolio of basic research on coronaviruses and emerging pathogens to characterize SARS-CoV-2 (the virus that causes COVID19) and understand how it causes disease. NIAID also is using animal models to better understand the infection and to investigate optimal ways to trea t and prevent COV ID-19 . 3. Are there topics or announcements for future press conferences (other than tomorrow's) that you would like to flag for the President's speechwriting team? -- For HHS to consider mentioning: (b) (5) -------------- From: Fauci,Anthony (NIH/NIAID) [El Date: Sunday,April 12, 2020 1 :55 PM To: Billet, Courtney (NIH/NIAID) [El ------~ Subject: RE: Staff Sec POC - NIAID -------- (b)(6) = (b)(6) OK. Sounds fine. Do what you can do . From: Billet, Courtney {NIH/NIAID) [E] CbH6)> Date: Sunday, April 12, 2020 10:59 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] CbH6)> Subject: FW: Staff Sec POC- NIAID ------~~ FYI- per request below, HHS is setting up a daily data call. We need to tell them at 9am what you are going to discuss at the daily press conference at the end of the day. My observation is that this may be hard to predict. However, we can certainly come up with some boilerplate talking points that we re-subm it every day, emphasizing the importance of properly designed clinical trials as the best way to identify treatments. From: Boyse, Natalie (OS/ASPA) Date: Saturday, April 11, 2020 7:04 PM ---------To: Billet, Courtney (NIH/NIAID) [E] ------~~ Cc: Bird, Catherine (OS/OGC) (b)(6)>; Agnew, Ann (HHS/10S) -(o- s-=; A_S_P_A '.""" ) -=====:!...:__::::____;_ (b ~ )~(6) (b)(6) (b)(6)> (b)(6) ,>; Puesan, Cesar (HHS/OS/I0S) (b)(6) 1>; Brennan, Patrick Subject: Staff Sec POC - NIAID Hi Courtney I hope you're having a good weekend. Just wanted to touch base because starting tomorrow, we will be receiving requests for information from Staff Sec each evening ahead of the next day's press conference - for a turnaround by 9am the following morning. Staff Sec is requesting feedback (see the questions below) from task force experts, including Dr. Fauci, on informa tion they recommend be included in the next day's press confe rence. Could you please help me identify a primary POC at NIAID that I can work with to get information to Staff Sec? (b) (5) (b) (5) Thank you , Natalie Natalie Boyse Special Assistant , Immed iate Office of the Secretary U.S. De artmen t of Health & Human Services M: (b)(6) From: Date: To: Cc: (NIH/VRC) [El Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 11 Apr 2020 03:05:04 +0000 Collins, Francis(NIH/OD) [El Tabak, Lawrence (NIH/OD) [El;Lane, Cliff (NIH/NIAID) [El;Mascola, John RE:COVID-19Advisory Panel Recommendations Following UP on Secretary Meeting this Am . I am sorry, but I am way behind on e-mai ls and I just saw this. From; Collins, Francis {NIH/OD) [El ------- (b)( What is going on here? > Date: Friday, April 10, 2020 11:02 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tab ak, Lawrence (NIH/OD) [E] ;;.========:c (b)(6) (b ~) ~ C6l;lane , Cliff (NIH/NIAlD) [E] (b)(6); Mascola, John (NIH/VRC) [E] (b)(6) Subject: FW: COVID-19 Advisory Panel Recommendations Following UP on Secret ary Meeting t his Am. Importance: High -------- Just saw this. Huh? --·? ------------------------- From: Kadlec, Robert (OS/ ASPR/10) (b) (5) CbH6)> Date: Friday, April 10, 2020 7:27 PM To: Hassell, David (Chr is) (OS/ASPR/10) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] CbH6)>;Collins, Francis (NIH/OD) [E] CbH6); 'shl@fda.hhs.gov ' CbH6)>;Mascola, John (NlH/VRC) [E] CbH6) Dareshori, Zack (HHS/IOS) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) CbH6)>;Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Blatner, Gretta (OS/ ASPR/BARDA) (b)( >; Patr ick, Vanessa (OS/ ASPR/BARDA) (CTR) -------- ...__-:--"""""."'-:--"""""':"'""""':":== (b= )(= 6):·:... _ M_o_u.:::, g_ ha_li_a..,;, n,~Jen ( HHS/ASFR) CbH6)>;Shuy, Bryan (OS/ASPR/10) CbH6);Redd, John (OS/ASPR/SPPR) CbH6) ; Redfie ld, Robert R. (CDC/OD) CbH6);Stre ngth-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) CbH >; Yeskey, Kevin (OS/ASPR/10) CbH6)> ; Marks , Peter (FDA/CBER) CbH6)>;Cochran, Norris (HHS/ASFR) (b)(6)>;Messonnier, Nancy (CDC/DDID/NCIRD/00) CbH6)>;Lane, Cliff (N lH/ NlAlD) [E] CbH6)>;Johnson, Robert -------- ------ (OS/ ASPR/BARDA) CbH6)>;Gershman, Lynn E. (CDC/DDPHSlS/0D) (b)(6b ; Lenihan , Keagan (FDA/OC) (b)(6); Mark Hartell ____________________ Cb _H_6) Mascola, John (NIH/VRC) [E] CbH6)>;Suhana, Tina (NIH/VRC) [El CbH6);Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NIAID) [E] CbH6)>;Mango, Paul (HHS/I0S) CbH6)>;Shuy, Bryan (OS/ASPR/I0) (b)(6) Cc: Harrison, Brian (HHS/I05) CbH6)>;Stecker, Judy (05/ 105) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) CbH6);Tignor, Beth (HHS/IOS) CbH6)> ; Moreno, --:---"'.'""'.""----::----::----::-:;======~ ~~ Rafael (OS/ASPR) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) (b)(6) ; Kemp, Micha (OS/ASPR/MFHC) CbH6); Holland , Tara (OS/ASPR/EMMO) CbH6)> Subject: RE: COVID-19 Advisory Panel Recommendations Following UP on Secretary Meeting t his Am. Importance: High ========:!....:.--~ ------~~ ---------- First thank you all for participating on Wednesday's evening call and producing the briefing memo for the Secretary's review. As a consequence of that meeting and discussion, he fully endorsed the recommendations of the vaccine portfolio you recommended . • (b)(5) This is an ambitious and challeng ing undertaking but one driven by the necessity to mitigate the public health, economic and national secur ity threat this virus represents to our citizens, nation and our way of life. The Secretary is confident that together with our private sector partners this is achievable. Have a restful holiday weekend. Bob From: Hassell, David (Chris) (OS/ASPR/I0) (b)(6) Date: Thursday, April 9, 2020 3:13 PM To: Kadlec, Robert (OS/ASPR/I0) CbH6)>;Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Collins, Francis (NIH/OD) [E] CbH6)>; --------=-:-= --------- CbH6)>;Dareshor i, Zack (HHS/I0S) ========~;:;;:;----::-:--:CbH6)>;Bright, Rick (OS/ASPR/BARDA)--------,;~ CbH6);Disbrow, Gary (OS/ASPR/BARDA) CbH6)>;Ford-Barnes, Arwenthia (OS/ASPR/I0) _:....:..._:_ _ __:_ __ ....:.!:==~~""'.""""--(b)(6); Blatner, Gretta (OS/ASPR/BARDA) ...=======Cb ~H~6);>--1 ;P '.'"' a-tr""." ic-:'k, Vanessa (OS/ASPR/BARDA) (CTR) CbH6) 1 >; Moughalian, Jen (HHS/ASFR)---------.. Cb "'>.,,., <6)>;Shuy, ---:---:---:--~-;=~....:....--=:........:.-__:.~= Bryan (OS/ASPR/I0) CbH6)Redd, John (OS/ASPR/SPPR) CbH6); Tignor , Beth (HHS/I0S) CbH >; Redfield, Robert R. "":"-~:---:-::====~= (CDC/OD) CbH6)>;Strength-McGaughey, Tracie (CDC/DDNID/NCIPC/0D) .,:.__:__...:...!::~;;:;-----:-(b)(6)>;Yeskey, Kevin (OS/ASPR/I0) CbH6)>;Callahan, Victoria (OS/ASPR/I0) (CTR) CbH6)>;Moreno, Rafael (OS/ASPR) CbH6)>;Marks, Peter (FDA/CBER) CbH6)>; Cochran, Norris (HHS/ASFR) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/00) (b)(6)>;Windom, Robert (OS/ASPR/I0) (b)(6)>;Lane, Cliff (NIH/ NIAID) [E] (b)(6) Holland, Tara (OS/ASPR/EMMO) CbH6)>;Johnson, Robert (OS/ASPR/BARDA)_______ --,;Cb -s--r H= >; ------- --------Gershman, Lynn E. (CDC/DDPHSIS/0D) CbH6)>;Kemp, Micha (OS/ASPR/MFHC) (b)( >; Lenihan, Keagan (FDA/OC) (b)(6)>; Mark Cb)( >; Mascola, John (NIH/VRC) Harte II [E] (b)(6)>;Suhana, Tina (NIH/VRC) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] CbH6)>;Fauci, Anthony (NIH/NI AID) [E] _ __:__;___.:..__ .:__:_ (b,.:... )( -c-: 6):--------- Subject: COVID-19 Adv isory Panel Recommendations Dear Panel membersSecretary Azar requested a summary paper w ith a recommendation from the Panel re the BARDA vaccine portfolio. His deadline was 3:30pm today. Based on the discussion last night and other discussions with the BARDA team, (b)(5) Please let me know as soon as possible if this is not the case. Apologies for the fast turn. Thank you again for your participation in the Panel. Chris << File: COVID Vaccines Briefing Memo V.3.docx >> -----Origina l Appointment----From: Kadlec, Robert (OS/ ASPR/I0) Date: Monday, April 6, 2020 1:36 PM --------- (b)( > To: Kadlec, Robert (OS/ASPR/I0); Conrad, Patricia (NIH/NIAID) [E] ; Collins , Francis (NIH/OD) [E]; (b)( 6); Daresho ri, Zack (HHS/I0S); Br ight, Rick (OS/ASPR/BARDA); Disbrow, Gary -----(OS/ ASPR/BARDA ); Ford-Barnes , Arwenthia (OS/ASPR/I0); Blatner, Gretta (OS/ASPR/BARDA); Patrick, Vanessa (OS/ AS PR/BARDA) (CTR); Mougha lian, Jen (HHS/ ASFR); Sh uy, Bryan (OS/ASPR/I0); Redd, John (OS/ASPR/SPPR); Tignor, Beth (HHS/IDS) ; Redfield, Robert R. (CDC/OD); Strength -McGaughey, Tracie (CDC/DDNID/NCIPC/0D); Hassell, David (Chris) (OS/ ASPR/I0) ; Yeskey, Kevin (OS/ASPR/I0); Callahan, Victoria (OS/ASPR/I0) (CTR); Moreno, Rafael (OS/ASPR); Marks, Peter (FDA/CBER); Cochran, Norris (HHS/ASFR); Messonnier, Nancy (CDC/DDID/NCIRD/0D); Windom , Robert (OS/ASPR/I0) ; Lane, Cliff (NIH/NIA ID) [E]; Holland , Tara (OS/ASPR/EMMO); Johnson, Robert (OS/ASPR/BARDA); Gershman, Lynn E. (CDC/DDPHS IS/00) ; Kemp, Micha (OS/ASPR/MFHC) ; Lenihan , Keagan (FDA/OC) ; Mark Hartel! (b)(6) Mascola, John (NIH/VRC) [El; Suhana, Tina (N IH/VRC) [E]; Marston, Hilary (NIH/NIAID) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: #2 - COVID- 19 Adv isory Panel When: Wednesday, April 8, 2020 5 :15 PM-6:30 PM (UTC-05 :00) Eastern T ime (US & Canada). Where: WEBEx Cb> cs) ----------- Presentatio n fo r Wedne sday. HIS ISTHE UPDATEDVERSIO ,4:26pm << File : BARDA COVID Vaccines Whi t e Paper 20200405b.docx » Meeting Objective: (1) Complet e review of BARDAvaccine portfolio (to includ e relat ed NIH and DoD pro grams), w ith emphasis on discussion amo ng Panel members; (2) Formu lat e a recomm endation to Secretary Azar to eith er endor se or modify curr ent vaccin e strategy, plans, proposed funding and contracts. Agenda Brief review of vaccine programs • BARDA (deeper dive after Sunday overview) • NIA ID • DoD Discussion Recommendat ion to Secretary Azar For convenienc e, below are the presentation and Whit e Paper from last Sunday evening . << File : BARDA COVID Portfolio Review 20200405b.pptx and HHS Leadership V2 FINAL - Gary.pdf >> >> << File: Vaccine Discussion with S1 Hi Arwenthia Ford-Barnes, You updated this WebEx meeting: #2 COVID-19 Advisory Panel on behalf of Dr. Robert Kadlec Host: Arwenthia Ford-Barnes When it's time , start your meeting from here: Start the meeting When: Wednesday, April 8, 2020, 5:15 pm (1 hr 15 mins), Eastern Daylight Time (New York , GMT04:00). Access Information Meeting Number : (b) (5) Password: (This meeting does not require a password .) Host Key: (b)(5 ) (Use this key during the meeti ng if you ever need to reclaim the host role.) Audio Connection ---- (b)(5 (Meeting Server Main Number) Access Code: (b) (5) Delivering the power of collaboration The meetingserver.hhs.gov team © 2020 Cisco and/or its affiliates. All rights reserved << File : BARDA COVID Vaccines White Paper 20200405b.docx » « File: BARDA COVID Portfolio Review 20200405b .pptx » << File: Vaccine Discussion with 51 and HHS leadersh ip V2 FINAL - Gary.pdf >> From: Date: (b)(6) Thu, 9 Apr 2020 16:48:20 -0400 To: Folkers, Greg (NIH/NIAID) [E);Conrad, Patricia (NIH/NIAID) [E) Fwd: Hello Subject: How do we nicely say no to this person? Begin forwarded message: From: "Sachdev , Amit (HHS /IOS )" ---------- Date: Apr il 9, 2020 at 2:04:56 PM EDT To: "Fauci, Anthony (NIH/N lAID) [E]" Subject: Hello ------~~ --------- (b)(6J: Hi Dr. Fauci, my name is Arn tt Sachdev. I am a Whi te House fellow and physician most recently at the Brigham . I know you are super busy and I wo uld love to partner wit h you and w rite a oped on coronavirus and un ite the nati on. If you have a few minutes, I would love to speak. I think Thank you for your time and consideration. Sincerely, Amit (b)(6) Sent from my iPhone (b)(S (b)(6) From: Date: To: Subject: Wed, 8 Apr 2020 20 :14 :10 -0400 Adams, Jerome (HHS/OASH) Re: Blacks/ minorities Please text to me your cell phone number On Apr 8, 2020, at 7:29 PM, Adams, Jerome (HHS/OASH) (bH (b) (5) Also, Deb has the data and knows it better than anyone , (b) (5) VADM Jerome Adams 20th US Surgeon General On Apr 8, 2020, at 7:13 PM, Adams, Jerome (HHS/OASH) (b) (6) >wrote: With greatest of respec t to the two of you , (b) (5) (b) (5) (b)(5 Jerome VADM Jerome Adams 20th US Surgeon Genera l Fauci, Anthony (NIH/N IAID) [E) Wed, 8 Apr 2020 14 :38 :40 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: HHS Sponsored Coronavirus Clinical Guidel ines - Heads up From: Date: To: Subject: FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ------------------=-:-= (b)( ' From: Stecker, Judy (OS/10S) Date: Wednesday, April 8, 2020 9:59 AM To: Harrison, Brian (HHS/105) (b)(6) Cc: (b)(6) (OS/10S) (b)(6)>; Fauci, Anthony (NIH/N IAID) [E] Cliff (NIH/NIAID) [E]!.======(b~)(=l>Y> -------- ~__;,_.....:...!:=~~----~- (b)( ·>; Lane, Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Thank you . Will have Beth connect with Patricia ASAP. Sent from my iPhone --------- On Apr 8, 2020, at 9:48 AM, Harrison, Brian (HHS/IOS) Cb) (6)> wrote: Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into this. Look forwar d to receiving and d iscussing the guidelines (no need for a separate meeting w ith me first - we can go straigh t to the Secretary) and agree t hat they w ill not be subjected to additional layers of fo rmal clearance given the circumstances. Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) Thank you Tony. Obviously we will prio ritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIA ID) [E] (b)( > wrote: -------- BLian, _·-------------------------- ~~ - CbX5)-PC (b) (5) ----------------------discuss further before I brief the Secretary . Cb H 5> Happy to Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. Fauci, Anthony (NIH/N IA ID) [E) Wed, 8 Apr 2020 13 :49 :56 +0000 Harrison, Bria n (HHS/IOS) RE:HHS Sponsored Coro navirus Clinical Guid elines - Heads up From: Date: To: Subject: Thanks, Brian. Anthony S. Fauci , MD Direc tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Harriso n, Brian (HHS/10S) (b)(6)> Date: Wednesday, April 8, 2020 9:49 AM To: (b)(6) (OS/10S) (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) ; Lane, Cliff (NIH/ NIAID) (b)( [E] (b) ~ ; Stecker, Judy (OS/10S) ---------------Subject: Re: HHSSponsored Coronavirus Clinical Guidel ines - Heads up Sounds good, Dr, Fauci - we greatly appreciate the effort that you/Cliff and your team have put into t his. Look forwa rd to receiving and discussing the guidel ines (no need for a separate meet ing with me first we can go straight to the Secretary) and agree that they will not be subjected t o add itional layers of formal clearance given the circumstances . Adding Judy to quickly help coordinate a time to meet with the Secretary. Thanks again, BH Brian Harrison Chief of Staff U.S. Department of Health and Human Services (b)(6) (b)(6) ------ (b)(6)> wrote : Thank you Tony. Obviously we will prioritize time to meet/discuss . I'm at your disposal. AMA On Apr 7, 2020, at 11:01 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wro t e: -------Brian: (b) (5) ------------Secretary. Best regards, Tony (b)(S) Happy to discuss further before I brie f the Anthony S. Fauci , MD Director National Institute of Allergy and Infect ious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confident ial and may conta in sensitive information . It should not be used by anyone who is not the original intended recip ient. If you have received th is e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa tives. From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 7 Apr 2020 14:48:49 +0000 Becks,Karen (HHS/10S) RE:Crazy C0VID-19 face cover idea Karen: Thanks for your note. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Becks, Karen (HHS/1OS) Date: Friday, April 3, 2020 12 :54 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Crazy COVID-19 face cover idea ------------------- (b)(6) CbH6) Hi, Dr . Fauci. Thank you so much for keeping things honest and know th at I am such a champion of you. I hope tha t reaching out is okay. I work at HHS/1OSteam. As I sit here at home and have been t hinking about the shortage of medical supplies, doggie cones actually can be used as protection for our health care workers. Just a thought that looks and sounds crazy but can help. Stay safe . Kindest Regards, Karen Becks U.S. Department of Health and Human Services Immediate Office of the Secretary 200 Independence Avenue, SW Washington, DC 20201 Desk: (b)(6) Mobi le: ----- (b)(6) ___ Brian Kamoie DHS/FEMA ,_ (b)(6) (mobile) From: Date: To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Thu, ~ r 202_022:05:53 +0000 (b)(6) RE:Greeti ngs from your former employee (UNCLASSIFIED) (b)(6) Many thanks for your kind note. I hope that all is well with you. Best rega rds ,. Tony -----Original Message- ---From: (b)(6) Date: Thursday, April 2, 2020 4:59 PM To: Fauci , Anthony (NTH/NIAID) [E] ____________ ......,........,...,.. _______ Subject: Greetings from your former emp loyee (UNCLASSIFIED) ------------------~~ (b) (6) (b _)_C_ CLASSIFICATION: UNCLASSIFIED Dear Dr. Fauci , 1 was in touch with (b)(6) back in January and he sa id you all were underwat er there with corona virus. I can only imagine how much busier you arc now, with COVID-19 taking bold across America. We (myself, husband, and family) have followed the news since the start . ln watching, I was reminded of the old sign we had posted on the printer between (b) (6).and my desk for quite some time that read, "Keep Calm and Trust Fauci". J can 't recall whe ther we put that up during the Ebola outbreak or Zika, but never has it been more true. We never cease to be amazed at how well you carry yourself , respond to politically loaded questions, and get the truth out in such a way that any viewer can understand. You also never seem to frustrate from answering the same question s which l am sure must get old. There bas been one question l have yet to hear asked howe ver. Who is cutting your hair? I know you used to have a regular ga l but with soc ial distancing, we are specul ating that perhaps there is a White Hou se barber you us e. Of course we know how busy you are so don't expect a reply, just wanted to throw you a question you may not have had yet. I am also wondering how your office tree is doing. How many bungee cords are sup portin g it these days? We have found plenty ofreasons to smi le with the who le family gettin g in on what we're dubbing the ASF # I Fan Club. From memes , to cartoon s, to l-shirt:;, we are all here support ing you and wishing for your continued health and success. I am attaching some of our shenanigans in hopes you get a kick out of it and to provide so me comic relie f. You've been thanked over and over but J must say it too. Thank you, Dr. Fauci, for all that you do. And thank you to the staff behind the sce nes that makes it happen. (b)(6) is no doubt just as busy as you as always are you reading this emai l? Hi !). When we see you at all hours from the NIH studio and your office, I think of the media staff support you receive, and espec ially assistance from (b) (6) for helping the ship run smoothly wh ile you are constantly engaged, ( (b) (6)} and your family , the list goes on. Thank you and thanks to your team. C ~, (b)(6) Directorate of Human Resources USAG Foti Detrick NIH-000065 CLASSIFICATION: UNCLASSIFIED NIH-000066 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIAID) [E) Fri, 27 Mar 2020 11:23 :56 +0000 Fauci, Anthony (NIH/NIAID) [El FW: Reaching out about partnerships and COVID-19. // confidential The email below is from Maria Freire . Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Immediate Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 (b)(6) (b)(6) ------- (b)(6) From: Freire, Maria (FNIH) [T] Se nt : Friday, March 27, 2020 6:03 AM To: Collins, Francis (NIH/OD) [E] (b)(6); Whalley, David (FNIH) [T] Cc: Fauci, Anthony (NIH/NIAID) [:"'=.E':'-:: ] ;:::::=====~ (b)~ (-= 6)>; Lane, Cliff (NIH/N IAID)._[_E_ ] ----- -----~~ (b)(6)> (b)(6)> Subject: Re: Reaching out about partnerships and COVID-19. // confidential Yes, quite a note . It is good to see such willingness to pitch in and the things J&Jis doing. Let us know what he says. We stand ready to help. Best, M . From: "Coll ins, Francis (NIH/OD) [El" (b)(6)> Date: Friday, March 27, 2020 at 4:37:15 AM To: "Wholley, David (FNIH) [T]" (b)(6)> Cc: "Fauci, Anthony (NIH/NIAID) [El" (b)(6J>, "Lane, Cliff (NIH/NIAID) [E]" (b)(6)>, "Freire, Maria (FNIH) [T)" (b)(6) ------Subject: FW: Reaching out about partnerships and COVID-19. // confidential HI David, Quite a message from Pau l below. collaborative He seems open to the idea of a virtual meeting, to see what efforts might be most important. I'll try to speak with him today or tomorrow. Francis ------- From: Stoffels, Paul [JJCUS) Se nt : Friday, March 27, 2020 3:54 AM (b) (6)> NIH-000211 To: Collins, Francis (NIH/OD) [E] (b)(6) Cc: Castillejos, Carlos [JJCUS ) (b) (6) Subject: Re: Reaching out about partnerships and COVID-19. // confidential Francis, (b) (4) Lots to talk about. Happy to find a productive way to contribute in the discussion you are planning to have. we can talk th is afternoon UStime or over the weekend. I'm working (b)(6) at the moment. Carlos can provide more information on the ---- (b) (6) Best regards, NIH-0002 12 if you want. Paul Sent from my iPad On Mar 27, 2020, at 1:37 AM, Collins, Francis(NIH/OD) [E) ------- (b)(6)> wrote: WARNING : This email originated from outside the company . Do not click on links unless you recognize the sender and have confidence the content is safe. If you have concerns about this email , send it as an attachment to 'SuspiciousEmail@ITS .JNJ.COM '. Hi again Paul, One more question - is the pharma collaboration mentioned in the BioCentury story below the same th ing as the Gates COVID Therapeutic Accelerator Program? Or is this something different? I'm just trying to understand the landscape. Best, Francis Pharmas on one page with action plan to solve COVID-19 together BIOCENTURYIS PROVIDINGTHIS STORYFOR FREEGIVEN THE URGENTNEED FOR INFORMATION ABOUT THE COVID-19 CRISIS. BY C. SIMONE FISHBURN,EDITORIN CHIEF I MAR 25, 2020 I 9:17 PM EDT A grand-sca le behind -t he-scenes effort by the pharmaceutical companies is under way to expedite the creation of therapies and vaccines to treat COVID-19. According to the participants who spoke with BioCentury under conditions of anonymity, R&D heads from at least 10 companies have been gathering several times a week, setting in motion an action plan to use their top talent in different disciplines to produce an industry-wide response, the likes of which haven't been seen since the private sector's coordinated contribution during World War II. Regulatory heads and manufacturing heads have been holding meetings as well, coordinating to minimize duplication of effort, streamline work and advance efficient testing of compounds and vaccines. The R&D group is creating working principles to accelerate new COVID-19 therapies and vaccines agnostic to their market potential , eliminating bureaucratic and technical or scientific barriers, and focusing on filling gaps not adequately filled by other initiatives and which the consortium is uniquely suited to address. NIH-000213 The pharma group's leaders also intend to offer resources to biotechs and academic groups pursuing countermeasures who may not want to join the effort but could benefit from expert guidance. Flying the plane as they build it, the collaborators intend to create a clearing house of ideas for testing of molecu les and vaccines, with working groups to vet the ideas and expedite testi ng on the most promising via clinical or preclin ical testing. According to the participants who spoke to BioCentury, the structure will probably evolve over time. Currently, the model involves five working groups, for clinical phase repurposing, novel small molecule antivirals, novel antibodies, prevent ive vaccines and preclinical repurposing. Each will be headed by a pharma R&D executive and will be responsible for prioritizing poten ti al compounds and specifying actions. Two platform groups will integrate across modalities: a clinical trial acceleration group and a data sharing group. "This is not a t ime to think about proprietary information or IP or margins. We need to break down the barriers and solve the problem," said one participant involved in the consortium. From: Collins, Francis (NIH/OD) [E] Date: Thursday, March 26, 2020 4:25 PM To: Stoffels, Paul [JJCUS) (b)(6)> Subject: RE: Reachingout about partnershipsand COVID-19 Hi Paul, I have done some work on the idea of an "AMP like" COVID project. As I mentioned, Mikael Dolsten has been quite enthusiastic. For FDA, Peter Marks, Janet Woodcock, and Steve Hahn were all extremely positive about this opportunity for a shared consideration about priorit ies. Tony Fauci and his team are totally in favor, and the FNIH (David Whalley and Maria Freire) stands ready to serve as convener . I thought the first step would be a 90 to 120-minute virtual meeting - hopefully next week. Attached is a draft precis of what t his might look like; I have left out the roster because that is very much a work in progress. Meanwhile I saw reports that there are related partnership discussions going on amongst pharmas: https://www.globenewswire .com/newsrelease/2020/03/26/2006713/0/en/Novartis -and-life -sciences-companies-commit expert ise-and-assets-to-the-fight-aga inst-COVID-19-pandemic-a Iongsid e-BiiIMel inda-Gates-Foundation. htm I NIH-000214 I am wondering how this might all fit together. Do you have a few minutes to speak with me about this? I'm at ----- (b)( , and I'd greatly value your advice. Just let me know when you m ight be able to ca ll, so that I'm not in the midst of a Zoom meeting. Best, Francis (b)(6)> From: Stoffels, Paul [JJCUS] Date: Tuesday, March 24, 2020 12:58 PM To: Collins, Francis (NIH/OD) IE]______ Cb _>_ <6l Subject: Re: Reaching out about partnerships and COVID-19 -------------~~ Absolutely worthwile . I wi ll write an email in the next hours. (b)(4) . Paul Verstuurd vanaf mijn iPhone Op 24 mrt. 2020 om 17:55 heeft Collins, Francis (NIH/OD) [E] (b)(6)> het volgende geschreven: ------- Hey again Paul, Really hoping to hear your thoughts on this proposal. FDA is highly enthusiastic. Dolsten is in. Other pharma R&DChiefs that would be most helpful? Jay Bradne r ? John Reed? Roger Perlmutter? Thanks, Francis From: Collins, Francis (NIH/OD) [E] Date: Monday, March 23, 2020 5:17 PM To: Stoffels, Paul (b)(6)> Subject: Reaching out about partnerships and COVID-19 Dear Paul, I've been thinking that th is is a time where we ought to have the best and brightest minds from industry, NIH, academia, and FDA around the same tab le to identi fy ways that we can move the coronavirus agenda forward to life-saving products as quickly as possible. Several pharmas and biotechs have been reaching out to NIH to ident ify viral assaysand animal models that can NIH-0002 15 be run in a BSL-3facility. Other similar contacts I've had with pharma and biotech tell me that there is a high degree of interest and willingness to combine forces at this time of crisis. This isn't exactly a precise recipe for AMP-COVID, but it has some of the same flavor. Would it be useful for FNIH to convene a virtua l meeting with a few heads of R&D (hopefully you; Mikael Dolsten has already expressed enthusiasm; and I'd be interested in your suggestions of others), FDA (Marks and Woodcock), leaders from NIAID and a few other NIH Institutes with equity in this space. We might be able to make a short list of catalytic actions that neither sector can do optimally right now, but together we can do rapidly . The focus would be on therapeutics and vaccines. But I can imagine a separate session on diagnostics . Does this sound worthwh ile to you? Thanks, I always value your advice and partnership . Francis NIH-000216 Fauci, Anthony (NIH/NIAID) [E] Thu, 2 Apr 2020 10:58:08 +0000 Mascola, John (NIHNRC) [E) FW: Secretary's Medical Countermeasure Advisory Panel From: Date: To: Subject: As per our d iscussion. From: Kadlec, Robert (OS/ ASPR/IO) (b)(6) > Date: Thursday, April 2, 2020 6:46 AM To: Bright, Rick (OS/ASPR/BARDA) CbH ; Disbrow, Gary (OS/ASPR/BARDA) Lambert, Linda (O5/ASPR/BARDA) (b)(6) Cc: Shuy, Bryan (OS/ASPR/IO) CbH >; Harrison, Brian (HHS/IO5) (b)( ; Hassell, David (Chris) (OS/ ASPR/IO) (b)(6)> Subje ct: Secretary's Medical Countermeasure Advisory Panel < CbH6); --------Importance: Rick, Ga High ry and Linda: The Secretary has directed me to establish a HHS Senior Adviso ry Panel of key HHS Operating Divisions( (NIH, CDC & FDA) to include head of agencies or their designees to oversee and provide recommendations to the Secretary concerning the development and procurement med ical countermeasures (MCM), (vaccines, therapeutics, diagnostics and devices). In meeting this direct ive, I have asked Dr. Chris Hassell to organize and serve as the intermediary to schedu le and coordinate. It is the intent to hold the first virtual meeting of this panel Sunday, 4 April time TBD. The frequency of further meetings wil l be determ ined at the inaugu ral meet ing . The Agenda should include : • Overall COVID-19 Strategy & Plan (5 min) • • Activities to Date (e.g. industry outreach, RFP BAA etc.) (5 min) High level overview of current MCM portfolio (5 min) • Detailed briefing of current vaccine technical development costs (30 min) • efforts, timeline and Discussion by participants (30 min) I ask that the materials for this meeting be subm itted by noon April 3 to the APSR 10 to be reviewed and be distributed to the Panel membership by noon Saturday April 4. Thank you Bob NIH-000082 From: Date: To: Subject: alleviate shortage Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 01:57:13 +0000 Kavesh, William RE:Medical staff need COVID-19 NIH surv ival data on N-95 respirators to help Dr. Kavesh: Thanks for your note. This issue is now being actively discussed at the Task Force meetings . No guarantee, but I believe that there will be movement in that direction. Best regards, Tony From: Kavesh, William (b)( > Date: Monday, March 30, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Medical staff need COVID-19 NIH surviva l data on N-95 respirators to help alleviate shortage ------~~ Dear Dr. Fauci, The biggest concern of my hospital colleagues is the shortage of protective masks. If any research is being done that might drive safe reuse of N-95 respirators, no one I know has seen it. These should be simple studies to do. If the virus is shown to die within a few days and moisture dries up, then the number of masks needing disposal could drop drastically. In that situation, each provider at risk could be given five N-95 masks, one for each day of the week . The provider would wear the N-95 mask for one working day, say Monday. and then place it into a paper bag in a secure location. The provider would not use that mask again until the following Monday; ie seven days later. The only question, then, would be: how many times can t his be repeated? Will t he mask lose any protective qualities over time? Please assign someone to do these studies soon . I'm also very pleased t hat our national leaders now seem to be listen ing to you more closely. Thank you for your efforts. William Kavesh MD, MPH CMC PhiladelphiaVA Medical Center NIH-000 117 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 15:26:47 +0000 Gottlieb , Lawrence A. RE:Support From: Date: To: Subject: Many thanks ! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"44 09 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------------- --=~ From: Gottlieb, Lawrence A. Date: Tuesday, March 24, 2020 11:19 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Support (b)(6) -------- (b)(6J> Dr. Fauci, Just want to express my support for your indefatigable effo rts to thwart the spread of the Coronavirus. Many , many years ago, I was a lab assistant for Dr. Edward L. Kuff and Dr. Karen Lueders, at NCI in building 37 !!! Bravo for all you are doing. Lawrence Gottl ieb, PMP, MBA, COR,FAC/PPM Ill Senior IT Project Manager Enterprise Portfolio Management Division Office of Information & Technology US Department of Veterans Affairs 810 Vermont Avenue, NW Washington, DC 20420 (b)(6) Office: Cell: Cb) .-!===~~ ------ (6) (b)(6) "Alea iacta est" - Caesar NIH-000255 VA Core Values: Integ rity Commitment Advocacy Respect Excellence VA U.S. Department of Veterans Affairs Officeof Information andTechnology nter r st Proa,...m \fo 'll'.l '.1 m, nr ,fnr; NIH-000256 NIH-000309 NIH-000310 NIH-0003 11 NIH-0003 12 (bX5)-PCI NIH-000 136 NIH-000 137 NIH-000 138 (bX5) -PCE NIH-00000 1 ~ NIH-000002 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 7 Apr 2020 13:42:04 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b)(6) ) FW: Keynot e Speaker Invitation - 8t h Interna ti ona l mRNA Health Conference No! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E) (NIH/NIAID) [E) Se nt : Tuesday, April 7, 2020 9:33 AM To: NIAID OD AM (b)( •> On Behalf Of Fauci, Anthony (b)(6)> Subjec t: FW: Keynote Speaker Invitat ion - 8t h Internat ional mRNA Health Conference From: Pardi, Norbert Date: Tuesday, April 7, 2020 9:07 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Keynote Speaker Invitation - 8th International mRNA Health Conference ------~~ Dear Dr. Fauci, On behalf of the organiz ing comm ittee, I am writing to invite you to Keynote the 8th International mRNA Health Conference (http://www.mrna-conference .com/ ) to be held at the Boston Park Plaza Hotel on Nov 9-10, 2020 . NIH-000003 The International mRNA Health Conference is a yearly non-profit event collaboratively organized by Curevac , BioNTech and Moderna. It brings together academic and industry thought leaders in the mRNA design and delivery space to explore the rapidly evolving science , business and regulatory landscape of mRNA medicines. Over the last seven years , this 2-day conference has become the premier destination for industry and academic professionals to network with colleagues , learn about the latest advances in mRNA technology, and to attend scientific presentations given by the most esteemed experts in the field. Notably, it is the only annual conference dedicated solely to mRNA therapeutics. As a scientist with tremendous experience and the director of NIAID, the organizing committee thought that conference attendees would very much appreciate hearing about your thoughts about mRNA therapeutics, particularly vaccines, and any perspectives you wish to share. The organizing committee recognizes that your calendar is likely filled years in advance, but we all have our fingers crossed that you might be able to fit this into your busy schedule. I look forward to hearing from you . all best wishes, Norbert P.S. In the event that the COVID- 19 crisis is still curtailing travel in the fall , our backup plan would be to have a completely virtual meeting on the same dates. We plan to make that decision in late AugusUearly September. Norbert Pardi, Ph.D. Research Assistant Professor of Medicine Infectious Disease Division Perelman School of Medicine NIH-000004 University of Pennsylvania Philadelphia, PA 19104 PH: 215-746-6552 pnorbert@pennmedicine.upenn.edu NIH-000005 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 7 Apr 2020 13:01 :12 +0000 Mark Feinberg RE:Greet ings and an Update : VSV-SARS-CoV-2 Vaccine Development Thanks, Mark. This e-mail is very inform at ive and helpful. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mark Feinberg Date: Saturday, Apr il 4, 2020 4:10 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) --------=-:-:= (b)(6)> --------- (b)(6>:>; Fauci, Anthony (NIH/NIAID) [E] Subje ct: Gr eetings and an Update : VSV-SARS-CoV-2 Vaccine Development Dear Tony, I hope you doing well despite yo ur heroically busy schedule and the complexi ty and magnit ude of the cr itically impo rtant issues you are work ing so hard and effect ively to address. You are providing such amazing and valuable leadership in the response to COVID-19 and the world is so fortunate to have you in t hi s key rol e! (b) (4) NIH-000006 (b)(4) Please let me know if you have any questions or would like any additional information . I will keep you posted (b)(4) . Be well and hang in there! Very best, Mark NIH-000007 Mark Feinberg, MD, PhD (b)(6) NIH-000008 (bX5) -PCP. NIH-000009 NIH-000010 (b)(S) - PCI NIH-0000 11 NIH-0000 12 NIH-0000 13 (b)(S) - PC! NIH-000014 NIH-0000 15 (bX5) -PCE NIH-000016 (bXS) - PCP NIH-000017 (bX5)-PCE NIH-0000 18 From: Date: To: Subjec t : Fauci,Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 17:30:06 +0000 Anki Wolf RE:Elizabeth Glaser Anki: Many thanks for your kind note. Best regards, Tony A.nthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Jnslitutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) f AX: (301) 496-4409 E-mail: (b) (6) The informalion in this e-mail and any of its a1tachmentsis confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please infonn the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and lnfectious Diseases (NJAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Anki Wol____________ (b ""' )""' (6) = Date: Sunday, April 5, 2020 5:25 PM To: Fauci, Anthony (NIH/NlAfD) [E) Subject: Elizabeth Glaser --------=-=-=-----------Cb)( HJ Dr. Fauci, l am (b)(6) you diagnosed with AIDS back in the mid I 980's. lt was in those early days of the AIDS epidemic that you were instrumental in diagnosing and researching this dreadful disease. (b)(6) My family had been associatedwith the NCI through my uncle, Lou Wasserman, who was a researcher for a period of time. Lou did much research on polycythemiavera and was a hematologist at Mt. Sinai in NYC. J'm glad that he's no longer around to witness the devastationof Covid-19. I was impressed with your knowledge at the time of (b) (6ldiagnosisand I am even more so in these times of the Covid-19 pandemic. Thanks for being the intelligent and informative face of the facts on the virus. There are many around the country who rely on your wisdom but also on your facts and data. Stay well, stay healthy, and keep providing the country with what we need to know and do. Be st, NIH-0000 19 Anki Wolf NIH-000020 From: Fauci, Anthony (NIH/NIAID) [E) Date: Mo n, 6 Apr 2020 17:27:18 +0000 To: Subject: Attachments : experiment.pdf, (b)(6) FW: clinical trials of Oral LL-37 on COVID-19 LL-37 ethic.pdf, three pati ents clinic al study.pdf, CAS001 Subchronic toxicity Internat ional research programme( l ).pdf , Wanzhu Jin CV.pdf Any suggestion of what to do with this type of thing? Can you have someone respond to them. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: JINWan-Zhu (b)(6)> Date: Sunday, April 5, 2020 11:45 PM -------= ------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: clinical trials of Oral ll-37 on COVID-19 = ·>; sunok301 (b)( -------- (b)(6) Dear Dr. Anthony S Fauci: Thank you very much for your hard work on COVID-19. You are the hero of word! This is Prof. Wanzhu Jin prof. Institute of Zoology, Chinese Academy of Sciences . (b) (4) NIH-00002 1 (b) (4) NIH-000022 (b) (4) Many thank s in advances ! Wanzhu Jin & Gang Sun NIH-000023 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 16:41 :38 +0000 info@marianneorlando.com Grady, Christine (NIH/CC/BEP) [El FW: Fauci superhero From: Date: To: Cc: Subjec t : M arianne: M any than ks for doi ng and sendin g t his. Best rega rds, Tony Anthony S . Fauci , MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in enor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Marianne Orlando Se nt : Friday, April 3, 2020 6:55 PM -----~= To: Fauci, Ant hony (NIH/NIAID) [E] (b)(6) Subject: Than k you, sir Dear Dr. Fauci, Being a freelance illustrator, I am tryin g t o keep myself producti ve dur ing thi s life-altering pandemic by doing a ser ies of COVID-19 inspired drawings. This is my late st, tha t I call: "My Personal Superhero." I dedicated it to you like thi s: "In his own, quiet way, he is a BadAss: Disseminating info about thi s disease calmly and, always, backed by science ." NIH-000024 Here is my drawing: So, Thank you, Sir. You are the voice of reason in what has been a dangerous, frightening situation. You are a real leader. Thank you, Marianne Francesca Orl ando Thank you , Marianne Orlando Marianne Orlando Illustrations (b)(6) NIH-000025 (b)(6) cell: .!:-'.-------. landline: (b)(6) MARIANNE:44 .. 1.J-gL.,.,.f-;A.,,._.j _ 0 RLANOO WM/YV'fMIVIATf'VY info@marianneorlando.com www.marianneorlando.com NIH-000026 Fauci, Anthony (NIH/N IAID) [E) Mo n, 6 Apr 2020 14:57:23 +0000 To: Billet, Courtney (NIH/N IAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El Subject: FW: Request for yo ur support in promoting new WHO recommendation for emergency response operation to provide universal accessto mandatory hand hygiene against COVID19 Atta chmen ts: who -interim -recommendation-on -obligatory -hand-hygi ene-againsttr ansmission-of-cov id-19 .pdf From: Date: Let us discuss. I am not sure what I should do with this. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)·> From: HOYER,Stefan Detlef Leo Date: Monday, April 6, 2020 8:34 AM To: Fauci, Anthony (NIH/ NIAID) [E)------= (b) ""'(6) => Cc: Emanuele CAPOBIANCO Cb)(6>b; GORDON,Bruce Allan (b)( 6)t >; ROGERS,Paul (b)(6) Subject: Request for your support in promoting new WHO recommendat ion for emergency response operation to provide universal access to mandato ry hand hygiene against COVID-19 Import ance: High ------- ------- ~-:--:-====~~-- Dear Dr. Fauci Please find enclosed the new WHO recommendat ion on establishing universal access to hand hygiene stat ions at thresholds of pub licly accessible buildings and means of publ ic transport. It is now officially published at : https://who.int/who-documents-detail/interim-recommendations-on-obligatory-handhygiene-against-transmission-of-covid -19 I attach a pdf copy for easy reference . I wou ld like to request your support in promoting the recommendation as part of an international emergency response operation providing un iversal accessto mandatory hand hygiene and/or sanitat ion against COVID-19 infect ions. Provided it is now made available and made ob ligatory whenever entering NIH-000027 and leaving a facility to wh ich the general public has access, it could become possible to prevent most smear infections by decontaminating all hands prior and after each possible contamination, both active or passive. In addition, the measure should massively reduce transmission of other viruses and bacteria currently burdening diffe rential diagnosis of COVID-pneumonias. Based on the excellent experiences made with t he acceptability and adherence during Ebola outbreaks, repeated mandatory hand hygiene or sanitation should thus become an almost unconscious routine of everyday life for any person having to leave his or her private home in Corona-affected countries. I have been asked by senior WHO emergency management to promote the WHO recomme ndati on for rapid implementation with particular focus on current COVID-19 transmiss ion epicenters such as the USA. Providing a systematic access to hand hygiene stations and making their use obligatory prior to entering and whenever leaving any public facility will also provide a safety net whenever current restrictions on movements and commerce are to be progressively reduced. Given the high resource settings in the current COVID-epicentres, and the negligi ble cost of implemen ting this public health emergency measure compa red to prolonged mass confinement without safe exit strategy, I do presume that the wherewithal to carry it out will not be limiting facto r. Thank you for considering the collaboration in this emergency measure proposed within th e USA at the largest possible scale. WHO has requested IFRCto alert the American Red Cross to support large scale implementation should your Government decide to implement the public health measure proposed. With best wishes for success in all of your endeavours, Stefan Hoyer Dr Stefan Leo Hoyer Medical Officer Focal Point for Emergencies Global Malaria Programme t: m: ______ (b) (6) ------ e: (b) (6) w: www.who.int/ma laria WorldHeaIth Organization NIH-000028 Fauci, Anthony (NIH/NIAID) [E) Mon, 6 Apr 2020 13:40:45 +0000 Jameson,James L RE:COVID-19 Rx From: Date: To: Subject: Than ks, Larry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Jameson, James L Date: Monday, April 6, 2020 9 :35 AM To: Anthony Fauci (b) (6) > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( 6) > (b)(6)> ---------- (b)( ; Fauci, Antho ny (NIH/NIAID) [E) Subjec t: Re: COVID-19 Rx Tony, Tcompletely understand - we are all thinki ng about you as you help the country .navigate this crisis - thanks so much. Let me know if there is any way that I, or people at Penn, can be helpful. Our scient ists, severa l of whom are Coro navirus experts (Susan Weiss, Paul Bates), have coalesced form a Center to focus on potential treatme nts and immuno logy related to the virus. I list few below and you might triage to others to flu further: (b) (4) NIH-000029 (b)(4) Best regards, Larry From: Anthony Faud (b)(6)> Date: Monday, April 6, 2020 at 8:25 AM (b)(6)> To: "J. Larry Jameson" Cc: Dennis Kasper (b)(6)>, Joseph Loscalzo _____ ....:.,_...:::====(b;::: )(;;6);;-J:-a-m_e_s_S ::h- a_n_a-;h-a_n_ ---------------, --=========::.....-=-c-"C=s (b a-: ),...,. (6) = Subje ct : Re: COVID-19 Rx Larry: I am so sorry that I have not gotten back to you and others in so long. I am completely swamped (3 to 4 hours sleep per night just does not work very well) and have not been able to even check my non-NIH (b)(6) . I will try my best to catch up soon. Thank for your understanding . Best regards, Tony --------- On Fri, Mar 13, 2020 at 9:33 AM Jameson, James L Dennis and Ton (b)(6)wrote: (b)(4) Best rega rds, Larry Anthony S. Fauci, M.D. Editor, Harrison's Principles of Internal Medicin e NIH-000030 Fauci,Anthony (NIH/NIAID) [E] Mon, 6 Apr 2020 02:27:39 +0000 Barasch,Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [E);schoofs@usc.edu From: Date: To: Cc: Subje ct : FW: 2nd try: Mark Schoofs reaching out Kim: Please have me call Mark tomorrow. Thank s, Tony From: Mark Schoofs Date: Sunday,April 5, 2020 7:28 PM To: Fauci, Anthony (NIH/NIAID) [E],------- ~(b-:)(= >; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: 2nd try: Mark Schoofs reaching out Hi Tony, God knows you are doing the world' s most important work right now, but if possible, I would love to talk with you for my COVID-19 project . I promised to keep it under 10 minutes, probably just 5. My cell: ------ (b)(6) All best , Mark From: Mark Schoofs Date: Saturday, March 28, 2020 10:04 AM To --------------------------Subject: Mark (b)(6) Schoofs reaching out Hi Tony, I hope you're hanging in there! If you have 5 minutes COVID-19 project I'm working on . My cell is ----- (b) (6) . Thank you . NIH-00003 1 10 max - I'd like to talk with you for a All best, Mark Schoofs Visiting Professor of Journalism University of Southern California NIH-000032 NIH-000033 NIH-000034 Fauci, Anthony (NIH/N IAID) [E) Sun, 5 Apr 2020 15:59:51 +0000 To: Marston, Hilary (NIH/NIAID) [El Subject: FW: GPMB: M ESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARD TELECONFERENCE - 30 MARCH 15:00 CEST Attachments: Statement on the COVID-19 pandemic and the Extraord inary G20 leaders' Summit - 1Apr2020 .pdf, GPMB Teleconference 30 March 2020 - Meeting Report 1 Apr 2020.pdf From: Date: Please check th is out and let me know if there is anything we need to do. Thanks. From: RIOUX,Amelie (b)(6) Date: Sunday, April 5, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID) [E] --------=~ (b)(6)> Cc: Marston , Hilary {NIH/NIAID) [El (b)(6)>; Steven T. Smith (b)(6) ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) >; SMITH, Ian Michael (b)(6) Subject: FW: GPMB: MESSAGEON BEHALF OF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE 30 MARCH 15:00 CEST Dear Dr Fauci, Please find attached the meeting report fro m the GPMB teleco nference o n 30 Mar ch 2020 and the GPMB co-Chairs' Statement on the COV/0-19 pandemic and the Extraordinary GlO Leaders' Summit on COV/0-19. I apologize, your email was deleted by mistake in the last two messages to the GPMB. With kind regards, Amelie GPMB Secretariat From: RIOUX,Amelie Date: Friday, 3 April 2020 14:18 To: 'VDzau@nas.edu' (b)(6)>; J.Farrar (b)( >; 'hfo re@unicef.org' (b)(6) (b)(6)>; 'Gao Fu' ':'"'.""--::======~,;;--.---:-:--:-:--:-.==========,=;e:;;' Gashum ba Diane' (b)(6)> ; Ilona Kiekbusch (b)(6); ---!:==== (b ":": )=(6) ~-'Skvortsova Vero nika' (b) ( >; 'Vega Morale s Jeanette' (b)(6) Subject: RE:GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, NIH-000035 Please find the link to the GPMB co-Chairs' Statement on the COVID-19 pandemic and the Extraordinary G20 Leaders' Summit on COVID-19 (also attached): https://apps.who.int/gpmb/assets/odf/Statement%20on%20the%20COVID19%20pandemic%20and%20the%20Extraordinary%20G20%20Leaders'%20Summit%201Apr2020.pdf We encourage you to circulate the Statement through your channels. You may wish to use the origina l hashtag fro m our report #AWorldatRisk in social media posts. Wi th kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy. From: RIOUX, Amelie Date: Wednesday, 1 April 2020 16:42 To: 'VDzau@nas.edu' (b)(6J; J.Farrar ; 'Gao Fu' ; 'Gashumba Diane' 'Skvort sova Veronika' (b)(6) Cb)(6) ----======-==---::--------=======~=;:Ilona Kiekbusch (b)(6)>; (b) ( >; 'Vega Mor ales Jeanette (b)(6J; --=======~.--(b) (6) (b)(6) Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST Dear Board Members, On behalf of the co-Chairs, please find attached the report from Monday's teleconference. With kind regards, Amelie GPMB Secretariat This message is being sent to GPMB members and their designated staff in copy . From: RIOUX, Amelie Date: Tuesday, 31 March 202009:17 To: 'VDzau@nas.edu' (b)(6) (b)(6J>; J.Farrar (b)(6) --------- (b)( NIH-000036 >; Ilona Kiekbusch (b)(6J>; 'Skvortsova Veronika' (b) ~ >; 'Vega Morales Jeanette' (b)(6)>; (b)(6) (b)(6) Scott Dowell -H:-a-::11 ==========================. ---:-:===================---~-- (b)(6) W illiam (b ~)~(;::;'=T:e-re_s_ a ~Miller de (b)(6) (b)(6) (b)(6) (b)(6) ; 'office-psa@nic .in' ; Toomas (b)(6)>; GPMB Secretariat ; GABEDAVA,Tsira _-...::====::e::::,,,,:;---:-(b)( 6) >; 'Steve Landry' (b)( > Subjec t: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST -------- MESSAGEON BEHALFOF THE GPMB CO-CHAIRSDR BRUNDTLANDAND MR SY Dear GPMB Members, Many thanks for your contributions to our teleconference, and to Jeremy and Victor for their very helpful report on the GPMB COVID-19 advocacy. Several of you mentioned that you had additional points that you might wish to make in writing; please do so as soon as possible, copying them to all Board members. If you have not already nominated a 'sherpa ' to represent you in the informal support group that will work with the secretariat, please do so as soon as possible. The secretariat is organizing a teleconference with the informal support group to follow up on the direction given by the Board on the annual report and work plan . Kind regards, Gro &As GPMB Co-chairs NIH-000037 From: RIOUX, Amelie Date: Monday, 30 March 2020 12:19 (b)(6)>; J.Farrar 'Gao Fu' ; 'Gashumba Diane' (b)(6); Ilona Kiekbusch 'Skvor ts ova Veronika' (b)(6) ; 'Vega Morales Jeanette' (b)(6) (b)(6) "'":"'"----:======~~-:---'"""':""~--:--::::==== (b)(6)>; -----!::::::~~;--:------ (b)(6); (b)(6) > ====~~~ (b (b)( 'Tore Godal' · SCHWAR · >; 'Pate Muhamed' >; SMITH, Ian Michael (b)(6) ; RYAN, Michael J. (b)(6l; 'Goda I, Tore' (b)( >; , ernhard F. (b)(6)>; Alveberg, Bened ikte Louise (b)(6)>; (b)(6) Scott Dowell (b)(6) William (b:;: )(~6);-'~T-e-re_s_ a _Miller de -"'.':":==========================::;: (b)(6) (b)(6) (b)(6) (b)(6) 'office-psa@nic.in' ; Toomas (b)(6); GABEDAVA,Tsira (b)( 6); 'Steve Landry' (b)( > Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS:PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15:00 CEST =========-=- -------- Dear Board Members and Colleagues, A kind reminder that Europe has switched to Daylight Saving Time over the weekend. The call takes place today at 15:00 Geneva time, which is 06:00 Seatt le time, 09:00 DC time, 21:00 Beijing t ime, and 22:00 Tokyo time. Best, Amelie From: SMITH, Ian Michael Date: Friday, 27 March 2020 19:19 To: (bH > (b)(6)>; Chris.Elias ------------ NIH-000038 (bH >; J.Farrar (b)(6) Fu' Cb)(6) --".'-:::======-=~~~--"'."".""-~-=======:-=~ umba Diane' (b)( >; Ilona Kiekbusch (b)(6)>; 'Skvortsova Veronika' -----.::::====:~i:'.""'.'"--:-:-- (b)(6)'Vega Morales Jeanette' (b)(6) (b)(6) (b)(6) (b)(6) (b)(6) (b)(6)>; >; 'office -psa@nic.in' ; Toomas Palu GPMB Secretariat ; GABEDAVA,Tsira (b)(6) RIOUX, Amelie (b)(6) ----.!::::==-=~~---(b)(6); 'Steve Landry' -------------Subject: RE: GPMB: MESSAGEON BEHALFOF THE CO-CHAIRS: PROPOSEDBOARDTELECONFERENCE - 30 MARCH 15 :00 CEST Dear Board members, dear Colleagues, Thank you very much to those of you who confirmed your participation in t he teleconference on Monday from 15.00-16.00 CET. If you have not done so yet, we would be grat eful if you could let us know as soon as possible . If you cannot attend, the co-Chairs would welcome your written comments in advance of the call. In prepa rat ion for the call, please find attached: 1. Agenda 2. Extraord inary G20 Leaders' Summit Statement on COVID-19 (shared with you earlier) 3. Update on the GPMB urgent COVID-19 funding call from the GPMB COVID-19 sub group 4. Overv iew of Existing Global Appeals and Funding Mechanisms for COVID-19 (for informatio n) The call- in details are copied below . Please note that as several of you have nom inated an Alternate to attend on your behalf, the co-chairs will invite Board Members to speak first, followed by Alterna tes speaking on behalf of Board memb ers. NIH-000039 Given the very limited time, the co-Chairs have asked that keep your interventions as short as possible. We look forward to the call. Please let us know if you have any questions. With kind regards, Ian Smith GPMB Secretariat ******** Call-inDetails: By clickingon the link Accessvia Web, you will find local and toll-free call-in numbers. Participant access -------- (b '"" )...(.-.. 4) Optional dial-in numbers internationa l +41 58 262 07 22 (English) +41 58 262 07 44 (Italiano) +41 58 262 07 11 (Deutsch) +41 58 262 07 33 (Fran~ais) Security code: For this conference a Security code is not necessary. Access via Web From: RIOUX,Amelie Date: Wednesday, 25 March 2020 14:16 To: ----==============~ Anthony Fauci (b)(6)· Gashurnba Diane (b)( 6) >; Skvortsova Veronika :;:::::======~~-- Cc: (b)(6);As Sy SCHWARTLANDER, Bernhard F.======== (b)(6)>;GodaI, Tore< Muhamed (b)(6)JeremyFarrar' (b)(6) (b)(6);Gao Fu (b)(6)>; CbH6l>;Ilona Kiekbusch (b)(6)>;Vega Morales Jeanette (b)(6) CbH6J; SMITH, Ian Michael Cb ""> ;:;~= 6) RYAN,Michael J_..:====~~ (b)(6)>;Tore Godal NIH-000040 >; Pate (b)(6); Toomas Palu ------==~~----(b)(6)> (b)(6J>;GPMB Secretariat CbH6J;GABEDAVA,Tsira ----------- Subject: GPMB: MESSAGEON BEHALFOFTHE CO-CHAIRS:PROPOSED BOARDTELECONFERENCE - 30 MARCH15:00 CEST MESSAGEON BEHALFOFTHE GPMBCO-CHAIRSDR BRUNDTLANDAND MR SY Dear Board Members, We wou ld like to propose to hold a Board teleconference on Mond ay 30 March 2020, 15 :00-16:00 CEST time. The purpose of the call will be to updat e you on the GPMB's COVID-19advocacy and t o discuss next steps. A more detailed agenda and call-in details will be shared shortly . ------ We wou ld appreciate if you could confirm your participation to Amelie Rioux Thank you for your continued support and engagement. With kind regards, Gro and As NIH-00004 1 (b)(6) Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:57:37 +0000 Teri McPeak RE:Association between Proton Pump Inhibitors and increased risk of Covid-19 From: Date: To: Subject: death Thanks, Teresa. From: Teri M cPeak Date: Saturday, April 4, 2020 5:44 PM To: Fauci,Anthony {NIH/NIAID) [E]______ """ (b"""" )(=6) Subject: Association between Proton Pump Inhibitors and increased risk of Covid-19 death Dr. Fauci, There is a wealth of medical rese arch papers about the association between Proton Pump Inhib itors (PPI) and increased risk of community acquired pneumonia. Long term use of PPls reduce the pH of the stomach from 1 to 5. This reduction in stomach acid reduces the body's ability to fight viruses. In addition, the lower stomach pH reduce the ability to absorb key nutrients that require gastric acid for breakdown and absorption (calcium, vitamin C & 812, iron, magnesium, potassium, zinc). Lack of proper nutrients lead to a compromised immune system. Seniors and individua ls with chronic illnesses are at higher risk of ploypharmacology and dying from Covid-19 due to PPls. The more medicat ions an individual tak es, the more likely they will suffer from acid reflux and thus be prescribed a PPL Thank you for your commitment and compassion during the pandemic. God bless you. Regards, Tere sa McPeak (b)(6) NIH-000042 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 5 Apr 2020 01:54:27 +0000 Silver, David (NIH/NCI)[C] RE:Question David: Thanks for the note. Since they both effected adequa t e quarantine, they are OK with each other ....provided that they practice physical distancing wit h everyone else, i.e. 6 feet apart and masks when out in situations where they cannot guarantee 6ft distance. With regard to your second question, it is not a question of temperature, it is a question of what surface the virus in on - stainless steel versus cloth, versus cardboard. Each of these have differ time frames of survival of replicatio n competent vi rus from a couple of hours to about 2 days. Best regards, Tony -------- From: Silver, David (NIH/NCI) [C) Date: Saturday, April 4, 2020 9:04 PM To: Fauci,Anthony (NIH/NIAID) [E] -------= Subject: Question (b)( (b,.,. ) =, (6) Dr. Fauc i, You are doing a great job and I am sure that things must be very challenging. Please let me know your thoughts on this, although I think I know the answer. Is it safe for them to see eac h other at this point? I was also wondering if it has been determined how long COV ID-19 can live in a refrigerato r or freezer. Thank you. Stay Healthy. David David Silver - Contractor (b)(6) National Institutes of Health , NCI Center for Biomedical Informatic s and Informati on Techno logy (CBIIT) 9609 Medica l Center Dr. NIH-000043 Rockville , MD 20850 NIH-000044 From: Date: To: Subjec t : (b)(6) Sat, 4 Apr 2020 15:50:32 -0400 anthony trocchi Re: An aquaintence from the past Tony: Thank you for your note. I hear you! Best rega rds , Tony -------- > On Apr 4 , 2020, at 12:25 PM , anthony troccbi > > > Hi Tony, You pro bably don't rememb er me, Twas (b)(6) > wrote: (b) (6) husband back when she was at NIH, you came to dinner at our hou se once. We also hung out in Boulder and drank beer together. I am just a working clas s guy, but keep up with science and politics for what it is worth. I don't know what you hear from the street level, but from here in . NY we are pretty concerned with the risk of Covid-19 and the Federal response to the pandemic. You have been the only reasonable voice in the administration. The leadership from the top is utterly lacking and incom pete nt and dangerous to the American people. You have had a long and venerab le career and I am asking you to stand up to power and speak the harsh truth to the peop le o f this country and the without regard to your personal consequences. We need a u11ifie d and professiona l federal response to this unprecedented c1is is. I think you may be the only person of re pute and status that ha s the power to change the course of h istory. I have spoken witti a good fr iend of mine who is a respected epidemio logist and he said that Covid-19 will infect half the population of the world an d those numbers are frightening statistically. My dad was born during the first worldwide modern pandemic and I don't really want to see him leave from this current one. I know I am somewhat out of place writing to you, b11ton e can onl y do what one can do to influe nce the events that hist ory arises from. With utmost respect. Tony Trocchi > Sent from my iPhone NIH-000045 From: Date: To: Subject: Vitamin C (b)(6) Sat, 4 Apr 2020 15:42:37 -0400 Stuart Coulter Re:Early Successesin ClinicalTrial on COVID-19Patients with High DoseIV Thanks, Stuart. I appreciateyour sendingme this information. I will pass it on to relevant program people. Best regards, Tony On Apr 4, 2020, at 3:38 PM, Stuart Coulter (b)( >wrote: Dear Dr. Fauci, Early Successes in ClinicalTrial on COVID-19Patientswith High DoseIV Vitamin C Thank you for the invaluable work that you are doing in guiding the United States through the current COVID-19 pandemic. I hope that you do not mind me contacting you, but I wanted to bring your attention to a clinical trial that is currently taking place in China on COVID-19 patients with high dose IV Vitamin C. There are reports of some early successes with this treatment and I wondered if this cou ld be a possible stop gap treatment - that cou ld possibly save many lives whi le we awa it the development of suitable drug treatments and a reliable vaccine. The trial in China is not due to conclude until September of this year, however, previous trials of IV Vitamin C have shown it to be a very safe treatment with litt le or no adverse side effects. I have read tha t the Northwell Hospital Group in New York, which operates 23 hospitals, have already started to give this treatment to many of their COVID-19 patients. This treatment also appears to meet the normally required criteria for a clinic trial. The treatment has been shown to be: 1) Effective (Please see the link below to the promising tria l results currently taking place in China). 2) Safe (The treatment has been shown to be safe in many previous tr ials going back well over 40 years). 3) Correct dosage is understood (The dosage is fully understood - please see the attached Protocol). 4) The correct patients to give this treatment to (Virtually everyone in hospital infected with COVID-19). 5) The correct time in the illness to give the treatment (As soon as the infected patient comes into hospita l). NIH-000046 I hope that you and your team find the details of this clinica l trial of some interest. The hospital protocol for this treatment is attached and here is a link to details of the current trial in China along with some other relevant links: http://www.orthomolecular.org/resources/omns/v16n18.shtml http://www.orthomolecular.org/resources/omns/v16n19.shtml http://www.orthomolecular.org/resources/omns/v16n07.shtml http://orthomolecular.org/resources/omns/vl6n21.shtml https://www.sciencedirect.com/science/article/pii/S2590098620300154?via%3Dih ub Kind regards, Stuart Coulter NIH-000047 From: (b)(6) Date: To: Subject: Sat, 4 Apr 2020 12:42:38 -0400 Conrad, Patricia (NIH/NIA ID) [E] Fwd: Interview Request: #1 Hiking Podcast FYI Begin forwarded message: Fro m : Zach Davi s Date: Apri l 4, 2020 at 12:39:25 PM EDT To: "Fauci , Anth ony (N IH/N JAID ) [E]" Subject: ln terview Request: #1 Hikin g Po dcas t --------== -------- CbH Hey Dr. FauciMy name is Zach Davis, I'm the founder and editor-in-chief at The Trek, a media company dedicated to long distance backpackers. Thank you for the tremendous service and leadership you've given this country during a time of great need. I'm reaching out to inquire about the possibility of your doing a short interv iew for our fl agship podcast, Backpacker Radio, the #1 rated hiking podcast on iTunes. We're putting together an episode related to how COVID-19 has impacted this year's class of backpackers, and would love to feature your expert insight on why social distancing is i mportant, and what the future may hold for our community. The interv iew would be alx>ut 20-25 minutes, though if you're only availab le for a shorter period, we'll take what we can get! Thanks for your time and thank you again for your terrific service to this country. Happy hiking, Zach Davis 11 editor-in-chief hikerlink I thetrek.co I backpackerradio founder NIH-000048 NIH-000049 From: Fauci,Anthony (NIH/NIAID) [E) Date: Sat, 4 Apr 2020 16:25:36 +0000 To: Folkers, Greg (NIH/NIAID) [E) Subjec t : RE:AFRICACDC:STATEMENTON MEDICATIONSTO TREATNOVEL CORONAVIRUSDISEASE Good for them!! ! From: Folkers, Greg {NIH/N IAID) (E] (b)(6) Sen t: Saturday, Apr il 4, 2020 12:2 1 PM Subject: AFRICA CDC:STATEMENTON MEDICATIONSTO TREATNOVELCORONAVIRUSDISEASE NIH-000050 From: Date: To: Subjec t : Attachment s: fi nal.docx Fauci, Anthony (NIH/N IAID) [E) Sat, 4 Apr 2020 15:18:14 +0000 Barasch, Kimberly (NIH/NIAID) [CJ FW: Excellent start to COVID PPP COVID PPPApril 3 actions.docx , Introductory call short bios - 3 Apr 2020 Please pri nt out these attachments and put into a folder labelled "COVID-19 Public Private Partnerships" Thanks. From: Collins, Francis (NIH/OD) [El (b)( > Date: Saturday, Apr il 4, 2020 10:26 AM To: (b)(6) (OS/IOS) (b)(6) Cc: Harrison, Brian (HHS/10S) (b)( ; Tabak, Lawre nce (NIH/OD) [El (b)(6); Fauci, Anthony (NIH/NIAID) [El (b)( > Subject: Excellent star t to COVID PPP ---------Hi Mr. Secretary, Just wanted to let you know - we had a very productive and significant two-hou r virtua l meeting with leaders of industry, FDA, and NIH yesterday . I attach the bios of those who attended - which includes the heads of R&D of nine major pharmaceutica l companies. There is unanimous support for bringing together all of the sectors to accelerate development of therapeutics and vaccines for COVID-19. Tony compared this to what happened in the early 1990s that led to successful ant ivirals for HIV. I attach the action items t hat came out of this meeting . Working groups for each of the four main top ics will be rapidly organ ized. I will keep you posted . Best, Francis NIH-00005 1 From: Date: To: Cc: Subject: (b)(6) Fri, 3 Apr 2020 16:42:08 -0400 Cantor, Harvey l.,M.D. NIAIDODAM Re: COVID-19 Harvey: Thank you for your kind note. It is much apprec iated. I will let the team know about your willingness to serve on committees and study sections . Best regards, Tony On Apr 3, 2020 , at l :20 PM, Cantor, Harvey I.,M.D. (b) (6)>wrote: Dear Tony, In t hese unsettli ng t imes, you are a much-appreciated voice of reason and proponen t of rationa l science. A great credit to NIH and NIAID...we're all very proud of you. I know that you have long advocated preparation of viral vaccines against future pandemic threats. I'm sure tha t it has been difficu lt to convince pharmas, charitable agencies and even the government to fund these efforts. which would include vaccine production and storage for indefinite periods. Perhaps there will be a greater will ingness to revisit a cost-benefit analysis of this effort in the near future. I would be happy to serve on comm ittee s, study sections etc. in an effort to increase our ability to identify and fund first-rate Immunology research that might accelerate innovative, safe and effective approaches to improved viral vaccines going forward. All very best regards, h. Harvey Cantor, MD Baruj Benacerraf Professor of Immunology Department of Immunology, Harvard Medical School Dept. of CancerImmunology &Virology, Dana-Farber CancerInstitute NIH-000052 Boston MA02215 (b)(6) The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient infonnation, please con tact the Pattners Compliance HelpL ine at http ://www.partners .org/compliance line. If the e-mail was sent to you in error but does not conta in patient information, p lease contact the sender and properly dispose of the e-mail. NIH-000053 From: Date: To: Subject: (b)(6) Fri, 3 Apr 2020 16:29 :45 -0400 Hasenkrug, Kim (NIH/NIA ID) [E] Re: Thanks from the troops Kim: Many thanks for your kind note . Best regards , Tony On Apr 3, 2020 , at l :56 PM , Ha senkrng, Kim (N IH/NIAID) [E] (b)(6) Hi Tony, I j ust want to express my sincere gratitude for all you are doing to get us through this crisis. Everyone I've talked to at RML expresses their deep admiration and apprec iation for your strong leadership, and we feel proud to be working for you. We listen to your hoarse voice every day. Personally, I have started two new lines of research to develop and test possible therapeutics for COVID-19. The cooperation and collaboration from everyone I've talked to , both here and around the nation, has been unb elievable. Please take care of yourself and stay strong and healthy for the sake of all of us ! Best regards, Kim Kim J Hasenkrug, Ph.D. Senior Investigator Chief, Retroviral Immunology Section Laboratory of Persistent Viral Diseases Rocky Mountain Laboratories Nat ional Institute of Allergy and Infectious Diseases National Institut es of Health 903 S. 4th Street Hamil to n, MT 59840 (b)(6) phon e ------ NIH-000054 FAX (406)363-9286 (b)(6) Disclaimer: The information in this e- mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases NIH-000055 (bX5)-PCI NIH-000056 NIH-000057 NIH-000058 Fauci, Anthony (NIH/N IAID) [El Fri, 3 Apr 202011:07:58 +0000 Ghafoor, Azam (NIH/NCI) [El NIAIDODAM From: Date: To: Cc: Subject: RE: Help Thanks for your note. I will circulate to others in NIAID From: Ghafoor, Azam {NIH/NCI) [E] _______ Cb _H_6)> Date: Thursday, April 2, 2020 11:10 PM To: Fauci, Anthony {NIH/NIAID) [E] ______ """ (b"""" )(=6) Subject: Help Dear Dr. Fauci, I am thoracic oncologist at the NC I. I wanted to commend you on your tremendous (and exhaust ing) job on managing and steering our country with the COVID - 19 pandemic. If you need add itiona l any personnel to help with any clinical or non-clinical aspects of the current situation, I am more than happy to help. As you know we have scaled down our clinical operations and trials at the NIH CC and so I have more time. Best regards, Azam Ghafoor, MD Assistant Research Physician & Staff Oncologist Thoracic Oncology Section Thoracic and GI Malignancies Branch National Cancer Institute, National Institutes of Health 10 Center Drive, Building 10, Room: 4G-5330 Bethesda, MD 20892 e: (b)(6) (b)(6) o: --==-- c: page ID Cb)(6) NIH-000059 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:40 :47 +0000 David Barr Giroir, Brett (HHS/OASH) ;Conrad, Patricia (NIH/NIAID)[El Introduction David: I am using this e-mail to introduce you to Adm. Brett Giroir who is the Assistan t Secretary for Health at HHS and a key member of the Coronavirus Task Force. I have explained to Brett the issues that you and your colleagues brought up over the phone with me the ot her night. Brett is willing o get on the phone with the group and go over some of t hese issues and per haps help t o resolve them. He is wait ing o hear from you. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX:(301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces. The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000060 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 02:10:12 +0000 Stephen Hahn (b) (6)' FDA release Steve: My staff just pointed out to me a _proposedFDA press release regarding convalescent plasma and hyperimmune globulin. The press release reads as follows: (b) (5) I just wanted to bring this to your attention for further consideration. Many thanks. Best regards, Tony NIH-00006 1 From: Date: To: Cc: (NIH/NIAID) [E];Bright, Mundel' Subject: Fauci,Anthony (NIH/NIAID) [E) Fri, 3 Apr 2020 01:53:59 +0000 Emilio Emini Conrad, Patricia (NIH/NIAID) [E);Mascola, John (NIH/VRC) [E];Erbelding, Emily Rick (OS/ASPR/BARDA) ;Collins, Francis (NIH/OD) [E] CbH6l;'Trevor RE:Connection Request per Bill Gates Emilio: Thank s for your note. As I had ment ioned to Bill yesterday evening, I am enthusiastic about moving towards a collaborative and hopefully synergistic approach to COVID-19 on the part of NIAID/NIH, BARDA and the BMGF. I will ask John Mas cola and Emily Erbe lding to connect with you to stay a conversation. Perhaps they can organize a call with you including BARDA. I will try to engage as much as I can given my current circumstances. We look forward to working with you. Best regards, Tony -------------------~~ From: Emil io Emini Date: Thursday, April 2, 2020 9:58 AM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Connection Request per Bill Gates ---------- (b)(6)> (b)(6)> Tony-I received a note from Trevor and Bill that they connected with you yesterday and they asked me to reach out . I've taken on the role of coordinating the foundat ion's contributions to the global COVID vaccine efforts, in particular fo r those approaches that are (or soon will be) in early development. There's an obvious need for coordination among the various primary funders or the focus we need to have given the state of the pandemic will become lost through uncoordinated activities . Bill tells me that you will take on a central role in coordinating BARDA'sfunding to t he ongoing efforts . And, of course, there are the NIH/VRC activities. I'm reaching out to ask how we can coordinate and cross-inform each other's activities. I am very sensitive to how busy you are and very grateful for your engagement. I see you on TV almost every day, and although you continue to have considerable energy, I am seriously worried about you. The nat ion and the wor ld absolutely need your leadership. As a next step we can connect 1: 1 briefly or you can pass this on to an appropriate member of your staff. - If you wish, you can always reach out to me directly at any time though my personal mobile at Pleasestay well. ...Emilio Emilio A. Emini, Ph .D., FCPP , FAAM Director NIH-000062 (b)(6) TB and HIV Program Bill & Melinda Gates Foundation NIH-000063 From: Date: To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 23:50:04 +0000 Glass, Roger (NIH/FIC) [El RE:COVID-19 in Africa: Tanzania Thanks, Roger. From: Glass, Roger (NIH/Fie) [E] Se nt : Thursday, April 2, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E] -------------~~ (b)(6) -------- (b)(6) Subject: FW: COVID-19 in Africa: Tanzania Tony, You have a fan club in Tanzania-Julie Makani and Lucio with your textbook! Keep up the heroic work . Roger From: Julie Makani Date: Wednesday, April 1, 2020 5:46 PM ------~= To: Glass, Roger (NIH/FIC) [E] ______ Cb _H_6J Subject: Re: COVID-19 in Africa: Tanzania Please pass greetings to Dr Fauci His authorship on Google Scholar including of Harrison's has been under discussion on social media Lucio has been writing the chapter on hemo lytic anemia He is heading to Italy for 3 months. He has been incredible . He was leaving his cop ies with the Sickle cell programme as we plan on getting keen scientists to read them Stay safe Prof Julie Makan i, T: ------ (b)(6) E: jmakan i@blood .ac.tz NIH-000064 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IAID) [El Thu, 2 Apr 2020 21:52:30 +0000 Lerner, Andrea (NIH/N IAID) [El;NIAID OD AM RE: My take on masks Thanks, Andrea ---------- From: Lerner, Andrea (NIH/NIAID) [El Se nt: Thursday, April 2, 2020 1:01 PM (b)(6) To: NIAID OD AM Subject: My take on masks Given our discussion this AM, just thought I would summarize my take on masks ac ross varying scenarios: (b)(5) NIH-000067 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 2 Apr 2020 21:14:40 +0000 To: Balasundaram, David (NIH/CSR) [El Subject: RE:Correlation between universa l BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Thanks, David. From: Balasundaram, David (NIH/CSR) (E] Date: Wednesday, April 1, 2020 7:19 AM (b)(6) To: Fauci, Anthony {NIH/NIAID) (E] -----(b = )""'(6) = > Cc: Balasundaram, David (NIH/CSR) [El (b)(6) Subject: Correlation between universal BCGvaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Importance:High Dear Dr. Fauci, I thought that you may be interested in reading this paper (Unless you already know about this of course!). This is obviously a data -driven set of correlative observations, but could be worth look ing into. I salute your outspoken efforts to galvanize this country into action in the midst of so many mixed messages and dragging of feet. Cheers, davtd David Balasundaram, PhD ., Scientific Review Officer, Cell Biology Integrated Review Group, http://public .csr .nih.gov/S tudySections/ lntegratedReviewGroups /CBIRG /Pages/default .as px Referral Officer, Division of Receipt and Referral ~ <:.mf'l'b ~ Sc,gn•l',c ~ ---------== 6701 Rockledge Drive , Room 5136, Bethesda, MD 20892-7768 Office (b)(6) I Fax: 301-480-1988 I Email: (b)(6) Integrity matters. Say something ! For concerns or quest ions about possible violations of peer review integrity, please contact your Scientific Review Officer , or the CSR Review Integrity Officer at csrrio@mail.nih.gov , or the NIH Review Policy Officer at reviewpolicyofficer@mail.nih .gov . See the NIH Guide Notice on integr ity in review. NIH-000068 From: Date: To: Subjec t : (b)(6) Thu, 2 Apr 2020 13:29:05 -0400 Vollmer, Sebastian Re: Estimate of undetected COVID-19 infections Thanks, Sebastian. Very helpful > On Apr 2, 2020, at 8:43 AM , Vollmer , Sebastian > ----------------- (b) (6}> wrote: > Dear Dr. Fauci , > > we have used estimates of COVTD-19 age specifc infection fatality rates and time from onset to death that were recently published in The Lancet Infectiou s Disease to estimate COVTD- 19 detection rates and the true number of infected people (in contrast to confirmed cases that are widely repo1ted) for the 40 most affected countries. We estimate a detection rate of on average six percent and number of cases of a few tenth of mi !lions. We thought you might be intere sted and have attached the note to this email. > > Thanks for doing such a great job in such a difficult time. I lived in Boston for a few year when J was a postdoc and later adjunct professor at the Harvard Chan School of Public Health. My thoughts are with my friends in the United States, particularly in New York. > > Warmly, > Sebastian Vollmer > > > > NIH-000069 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 13:02:41-0400 Jim West Re:THANK YOUTONY! Jim: Thank you for your kind note. It is much apprec iated. Best regards, To ny On Apr 2, 2020 , at 10:08 AM , Jim West --------- (b)( >wrote: Dear Tony, My name is Jim West and (b)(6) Most people did not know (b)(6)·, except his immed iate family, close friends and of course Jack Whitescarver. I am writing to congratulate you on the job you are doing with the Coronavirus. There is no doubt in my mind it has been exceedingly stressful for you and your family, and I just wanted to offer my support and reassurance that you are indeed doing a great job. I know (b)(6) could have never handled the stress of all of this, and he would be most proud of the j ob you are doing . Take good care of yourself and keep steadfast in what you are doing. You are the true medical advisor of the United States during this pandemic, and mill ions of us are incre dibly grateful. Sincerely yours, Jim West NIH-000070 (b)(S) - PCf NIH-00007 1 (bX5) -PCI NIH-000072 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [E) Thu, 2 Apr 2020 13 :21:29 +0000 WAYNEREYNOLDS RE:Heads Up - Dr. Fauci Bobblehead w ith a Cause Wayne and Catherine: Thank you for your kind note . Much appreciated . Please stay safe and well so that we can some time soon (I hope) resume our normal lives together. Best regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices . The National Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability fo r any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: WAYNE REYNOLDS Date: Wednesday, April 1, 2020 3:43 PM To: Fauci, Anthony {NIH/NIAID) [El Cc; Grady, Christine (NIH/CC/BEP) [El (b)(6)> ------~~ (b)(6):> CbH > Subject: Fwd: Heads Up - Dr. Fauci Bobblehead with a Cause Tony, You've finally hit the big time. The National Bobble head Hall of Fame and Museum. Tha nk you for all you' re do ing for the country. Warmest wi shes, Wayne and Catherin e Sent from my iPhone NIH-000073 Begin fo rw arded m essage: From: "Jordan, M ary" Date: Apri l 1, 2020 at 3:39:44 PM EDT To: Way ne Reynolds (b)(6)> Subject: Fw: Heads Up - Dr. Fauci Bobblehead with a Cause W ho knew there w as a Nat ional Bobblehead Hall of Fame and M useum ! From: Phi l Sklar Date: Wednesday, Apri l 1, 2020 3:34 PM To: Jorda n, Mary Subject: Heads Up - Dr. Fauci Bobb lehead with a Cause ICAUTION:EXTERNALSENDER Hi Mary , I hope you are staying well dur ing these unprecedented times ! I want ed to give you a heads up that we will be unveiling a bobb lehead of Dr. Anthony Fauc i this Friday, Apri l 3rd . Dr. Fauci has become Amer ica's voice of reason as one of the lead member s of the Wh ite House Corona virus Task Force. The Na tional Bobblehead Ha ll of Fam e and Museum w ill be donatin g $5 from every Dr. Fauci Bobblehead sold to the American Hosp ita l Association in support of the I 00 M illion Mask Challenge [icm-track ing.meltwater .com] . The bobb leheads will be available for preorder on our website beginning on Friday . Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it g iven what he has don e and continues to do for our country and the world in the battle against COVID-1 9. Th e bobblehead will j oin a grow ing number of items including donuts, socks and t-shirts featuring Dr. Fauc i. We rece ived a lot of requests for a bobblehead of Dr. Fauc i and are excited to be able to use the bobb lehead to raise funds for a vital organization that is helping limit the spread of the Coronavims whi le makin g people smi le dur in g these unprecedented times. Let me know if you would like the press release, pictures and gra phics in advance of Friday 's release. Please hold off on publicizing anything related to the bobblehead unt il Friday- any time on Friday is okay. Please also let me know if you would lik e a samp le when they an-jve or if you have any quest ions. T hank you, NIH-000074 Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar @bobbleheadhall.com 414-519-2625 www.bobbleheadhall.com [icm-tracking .meltwa ter.com] This email was sent to mary.jordan@washpost.com National Bobblehead Hall of Fame and Museum , PO Box 0982 , Milwaukee, WI 53201-0982, us Unsubscribe [icm-tracking.meltwater.com] NIH-000075 From: Date: To: Fauci, Anthony (NIH/N IAID) [E) Thu, 2 Apr 2020 12:59:53 +0000 Auch incloss, Hugh (NIH/N IAID) [CJ Subject: FW: COVID-19 Planning (b)(6) Let us discuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ta bak, Lawrence (NIH/OD) [El (b)(6) Date: Wed nesday, Apr il 1, 2020 7:35 PM To: ICDDIR-L@LIST.NIH .GOV; List DEPDIR-L Cc: NIH Director's Executive Committee Subject: Re: COVID-19 Planning Importance: High Colleagues, The momentum behind a 4 t h COVIDsupplement seems to be building in the Congress even more quickly than we had expected. We have received a TA request to prov ide rough numbers for NIH efforts by Friday afternoon. With regrets for adding more burdens to the intense efforts you are already engaged in, I ask that you submi t a rough estimate of the first year and t he five year budget for your (i) IC-specif ic init iat ive(s) and/or your (ii) proposa ls to contr ibute to economic recovery, no later than Friday April 3 at noon. This will be non-binding, and you are free to revise it fo r the submission that we already asked you for by Friday COE.The only thing we need Friday at noon is the budget - the narrative can come later in the day (or the night). Please use the second page of the t emplat e we sent you yesterday to provide this draft budget. Send to me . NIH-000076 I apologize for the impossible turn-around and appreciate al l the hard work that will be needed to get us this information by the Friday noon deadline. Many thanks, Larry From: "Tabak, Lawrence (NIH/OD) [E]" < (b)(6J > 1 Date: Tuesday, March 31, 2020 at 4:20 PM To: " ICDDIR- L@LIST.NIH.GOV " , List DEPDIR-L Cc: NIH Directo r's Executive Committee <0D -SmallStaff@mail.nih .gov > Subje ct : COVID-19 Planning Colleagues, Francis is sending out a note shortly to the co-chairs of each of the ten tra ns-NIH initiatives, asking for their assistance in putting together wo rkplans and budgets for those projects. But in addition to these trans- NIH activities, we invite ICDsto submit a short description of no more than two IC-specific ideas that you believe merit consideration for support in a fourth supplemental bill, should one be put forward. Please use the same template that is being used for th e tran s-NIH activities, but ju st check the appropriate tick box. Your submission should include budget estimates for the first year and subsequent outyears (for a total of 5 years). (b)(5) . Pleasesend these to me by COE,Friday, April 3rd . Finally, l! we are asked about t echnical assistance regarding economic recovery, please send ideas for that option. As part of this, Mike Lauer and Michael Gottesman will submit estimates on what might be needed for extramural institutions and the IRPto "make them whole" . However beyond that there are infra structu re, training, and other requests that wou ld with help national economic recovery by creating new jobs (construction, IT, biomedical, etc.) and help prepare the nation for COVID-202X.Pleaseuse the same template that will be used for the trans-NIH activities (again, checking the correct box) and include budget estimates for the first year and subsequent outyears (for a total of 5 years). Please send these to me by COE,Friday, April 3rd . Many thanks, Larry NIH-000077 From: Date: To: Subject: (b)(6) Thu, 2 Apr 2020 07:28:32 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: media inquiry on COVID-19 Begin forwarded message: From: "stefano. va lentino @globalreporter.it" Date: April 2, 2020 at 5:54:54 AM EDT To: "Fauci, Anthony (NIH/N IAID) [E]" Subject: media inquiry on COVID-19 Dear Dr. Fauci, I am a Brussels-based journalist, member of the European Data Journalism Network (EDJNet) , a digital news-making platform that affiliates media outlets across Europe. I found a quote from you in this article which seems to be quite prophetic: https ://www.theatlantic .com/health /archi ve/2020/02/covidvaccine / 607000/ I contact you to have a discussion about the effectiveness of the epidemic outb reak preparedne ss and response measures put in place by governme nts, particularly in te1ms of vaccine development. I would like to know if we could ave a chat on sk:ype. Or, if you prefer, I can send you some questions by email. I wait for your kind feedback Regard s Stefano Valentino Founder MobileReporter Special Investigations Contributor VoxEurop NIH-000078 Fatto Quotidiano Fullbright Alumni Berkley School of Journalism Memberships: Italian Press Association European Data Journalism Network Italian Science Writers Association Society of Environmenta l Joumas/ists Online News Association Tel: .___.., CbH6l ,__,,~ Whatsapp: CbH6) Skype: globalreporter Twitter: @M0BILEREP0RTER i nfo@mobilereporter. info www.mobilereporter.info NIH-000079 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 2 Apr 2020 10:58:29 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Possible lneterview via FaceBook To: Subjec t : fyi From: Brendan Taglianetti Se nt : Thursday, April 2, 2020 6:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Possible lneterview via FaceBook ------ == (b)(6)> Dear Dr. Anthony S. Fauci, My name is Brendan Taglianetti; I am a Full-Time Advanced EMT provider for Milford Ambulance Service in Milford, NH. I want to help relay your message of COVID-19 information for state of New Hampshire, by conducting a Facebook Live chat with myself to project information and messages to the citizens of New Hampshire . This is a chance for us to chat for around 10 minutes and ta lk with a first responde r to the general public. I have seen you do interviews with the media/ daytime talk shows, a Facebook live chat with Mark Zuckerberg, and even an lnstagram live video with Stephen Curry from the Golden State Warriors. I run the social media aspect of the departmen t, and I would love to do a 10-15 minute discussion (with information to the public, as well as some question and answer) with you on Facebook (live) to have the general public watch us talk about the pandem ic and the next steps, and also maybe take some questions asked of the publ ic watch ing when they comment. I also w ill be reaching out to the New Hampshire State Governor Chris Sununu and Dr. Benjamin P. Chan (who is the state's epidemiologist). I would love to have them chat with me, and have you join in on the discussion as well. I have no confirmed with them if they are available yet, but I am putting things in motion. I know that if I was able to set up a time and date that would work around your busy and important schedule, then I could with ample time promote it. I would love to not only get the town on Milford to watch th is, but have the state of New Hampshire and other states nearby tune in. I know this is a long shot and that you have way more important aspects of your job to complete, but I think th is an important time to have the public hear you talk. Please let me know if this could be possible and I would love to set this up, I don't expect to take too much of your time if this can happen. Sometimes in life you jus t need to ask and see what happens and this is a t ime where that risk is worth it to have a conversation with you about this pandemic we are facing, especially as we ramp up for starting to "peak" in the number of people affected . NIH-000080 Please let me know if this is possible and tell me if you are interested in doing this with us for the greater goo d of the general public to keep them informed . Sincerely, Brendan J. Taglianett i Full-Time Advanced EMT/ Field Training Officer Milford Ambul ance Service 66 Elm Street, Milford , NH 03055 Phone: (603) 249-0610 (ext . 275) Email: btaglianetti@milford.nh.gov NIH-000081 From: Date: To: Subjec t : (b)(6) Wed, 1 Apr 2020 22:15:42 -0400 McNeil Jr, Donald G Re: Heads Up - Dr. Fauci Bobblehead w ith a Cause Yikes!!! On Apr 1, 2020, at 9:55 PM, McNeil Jr, Donald G wrote: - I'm order ing one for my office desk and maybe anothe r for --- (b)(6) ----------Forwarded message --------From: Phil Sklar Date: Wed, Apr I, 2020 at 3:35 PM Subject: Head s Up - Dr . Fauc i Bobblehead with a Cause To: Hi Donald, I hope you are staying well during these unprecedented times! I wanted to give you a heads up that we will be unveiling a bobblehead of Dr. Anthony Fauci this Friday, April 3rd. Dr. Fauci has become America's voice of reason as one of the lead members of the White House Coronavirus Task Force. The National Bobblehead Hall of Fame and Museum will be donating $5 from every Dr. Fauci Bobblehead sold to the American Hospital Association in support of the 100 Mil lion M ask Challenge. The bobbleheads will be available for pre-order on our website beginning on Friday. Bobbleheads are the ultimate honor, and we think Dr. Fauci deserves it given what he has done and continues to do for our country and the wor ld in the battle against COVID-19. The bobblehead will join a grow ing number of items including do nuts, socks and t-shirts feat uring Dr. Fauci. We received a lot of requests for a bobblehead of Dr. Fauci and are excited to be able to use the bobblehead to raise funds for a vital organ ization that is helping limit the spread of the Coronavirus while making peop le smile during these unprecedented times. Let me know if you would like the press release, pictures and graphics in advance of Friday's release. Please hold off on publicizing anything related to the bobble head until Friday-any t ime on Friday is okay. Please also let me know if you would like a sample when they arrive or if you have any questions. NIH-000083 Thank you, Phil Phil Sklar Co-Founder and CEO National Bobblehead Hall of Fame and Museum Phil.Sklar@bobbleheadhall.com 4 14-519-2625 www.bobbleheadhall.com This email was sent to mcneil@nytimes.com National BobbleheadHall of Fame and Museum, PO Box 0982, Milwaukee, WI 53201-0982,us Unsubscribe Donald G. McNeil Jr. Science Correspondent l~r~rwflorkeimcs Tel: (b)(6) mcneil@nytimes.com Articles: https://www.nytime s.com/b y/dona ld-g-mcneil- jr NIH-000084 From: Date: To: Attachment s: Guard in.of t, message, Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 19 :59 :55 +0000 Aw wad, David (NIH/ NIAID) [C] message,, Re message.oft, Re messagel.oft, u r hypo crite .oft , Call the Nat ional Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000085 From: (b)(6) Date: To: Subject: Wed, 1 Apr 202017:51:34 -0400 Duchin, Jeff Re: FEMA Test Kits Je ff: Thanks for yo ur note. It was very helpful to me to speak with yo ur group last night. I caused quite a stir at the Task Force meetin g when I repo rted on our telephone conversat ion. I believe that this fixed the FEMA issue . Best regards , T ony On Apr l , 2020, at 5:43 PM, Duchin , Jeff ------------ (b)(6) wrote: Tony, Thank you for taking some precious time to hear from some of the folks on the ground confronting COVID-19 around the country. I can't tell you how much we all value your engagement and leadership on behalf of the nation. I'd love to get your take on whether you think the type s of things described it eh recent AEI report are realistic. I have serious doubts. Quick question - I ment ioned the problem we had with FEMA test kits being recalled from us because we did not want to use their call line and lab because too slow, - just wondering if that came up in your meeting today because I just heard the kits were released to us without restrictions on how we use them. So either way, apparently resolved. Stay well and best regards, Jeff Jeffrey S. Duchin, MD Healt h Officer and Chief, Communicable Disease Epidemiology &Immunization Section Public Health - Seattle and King County Professor in Medicine, Division of Infectious Diseases, University of Washington Adjunct Professor, School of Public Health 401 5th Ave, Suite 1250, Seattle , WA 98104 Tel : (b)(6); Direct : (b)(6); Fax: (206) 296-4803 (b)(6) E-mail: ---------- NIH-000086 (b)(6) From: To: Wed, 1 Apr 2020 16:54 :57 -0400 Kadlec,Robert (OS/ASPR/10 ) Subject: Fwd: Date: Bob: See emai l below. (b)(5) ------------------------ (b) (5) Thanks, Tony Begin forwarded message: From: "Mascola , John (NIH N RC ) [E]" Date: Apr il 1, 2020 at4:40:39 PM EDT To: "Fauci, Anthony (NIH/NJAID ) [E]" Cc: "Conrad , Patricia (NIH/N IAID) [E]" Emi ly (NIH/N IAID) [E]" (NIH/N IAID) [E]" ____, Subject: --------- (b)( (b)<6) 1, "Erbelding, (b)(6) ,... S,- ,-,M - a-r-st-on_ H_.ilary ' ' __________--- Tony , (b) (5) John NIH-000087 (b) (5) NIH-000088 Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 16:02 :51 +0000 Barasch,Kimberly (NIH/NIAID) [C);Conrad, Patricia (NIH/ NIAID) [E) From: Date: To: (b)(5)- PC Subject: Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . (b)(5)- PCI NIH-000089 (bX5) -PCl1 NIH-000090 (bX5) -PCl1 NIH-00009 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Wed, 1 Apr 2020 16:01:03 +0000 Gallo, Robert Barasch, Kimberly (NIH/NIAID) [C];Conrad, Patricia (NIH/NIAID) [El RE:information I got it. I will have my staff try to set something up. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Gallo, Robert (b)(6) Date: Wednesday, April 1, 2020 11:15 AM ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: information (b)(6) TONY-this is from me-Bob Gallo -------Date: Wednesday, April 1, 2020 11:08 AM From: Fauci, Anthony (NIH/NIAID) [E] To: Gallo, Robert (b) ~ > Cb)(6) Subject: RE: information My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards . NIH-000092 Anthony S. Fauci, M.D. NIH-000093 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 1 Apr 2020 14:04 :37 +0000 Berkowitz, Avrahm J. EOP/WHO;Gidley, Hogan H. EOP/WHO RE:Quick call (b)( 5) Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ------- From: Berkowitz, Avrahm J. EOP/WHO Date: Wednesday, April 1, 2020 9:48 AM To: Fauci, Anthony (NIH/ NIAID) [E) ______ -----~~ (b)(6) Cb_H _, 6)>; Gidley, Hogan H. EOP/WHO (b) (6) > Subject: Quick call Dr Fauci - can you please jump on a quick call with Hogan about a press inqu iry we received at the White House? He is at (b)(6) (and I am at (b)( . Thank you! Avi NIH-000094 Fauci, Anthony (NIH/N IA ID) [E) Wed, 1 Apr 2020 13:22 :58 +0000 (b)(6) From: Date: To: RE:FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus exper t attracts a cult follow ing Subjec t : It is not at all pleasant, th at is for sure. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: (b)(6) Date: Wednesday, April 1, 2020 9:14 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: FW: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art : The coro navirus expert attracts a cult follow ing ---------=-::-:-= --------- Completely surreal (b)(6)Dizzying, even . Can't imagine wh at it is like for you, especially in the midst of all t his. On Tue, Mar 31, 2020 at 10:58 AM Fauci, Anthony (NIH/NIAID) [E] ______ Truly surrea list ic. Hopefu lly, t his all st ops soon. A nthonv s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301) 496--4409 E-mail Cb)( NIH-000095 Cb> _C_6)> wrote: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b)(6)> From: Folkers, Greg (NIH/NIAID) [E] Date: Tuesday, March 31, 2020 10:43 AM Subje ct: Wpost: Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attract s a cult --------- following Fauci socks, Fauci doughnuts, Fauci fan art: The coronavirus expert attracts a cult following Doughnuts bearing the likeness of Anthony S. Fauci, director of t he Nation al Institute of Allergy and Infectious Diseases, rest on a plate at Donuts Delite in Rochester, N.Y., on March 25. (Shawn Dowd/Rochester Democrat & Chronicle/AP) By Antonia Noori Farzan March 31, 2020 at 5:15 a.m. EDT Early last week, Nick Semeraro wanted to find a way to hono r Antho ny S. Fauci. As the owner of a small doughnut shop in Rochester, N.Y., he had been closely tracking the latest news about the coronavi rus pandemic. And night after night, he'd been impressed by how Fauci, the director of the National Institute of Allergy and Infectious Diseases, approached the crisis in a calm, knowledgeable manner. So, as a tribute , Semeraro put th e renowned immunologist's face on a doughnut. Expecting to sell a few hundred, he was shocked when the store sold out day after day, with thousands flying off the shelves. Donuts Delite was besieged w ith requests to ship the buttercream-frosted creat ions all over the country, and one Fauci fan drove three hours just to pick up a dozen. Soon, bakeries in Wisconsin and Pennsylvania followed suit, using edible paper to decorate pastries with Fauci's likeness. "We had no idea it was going to blow up thi s big," Semeraro told CNN."We didn't know everyone else felt the same way we did ." While Fauci was already a respected scientist before the outbre ak, his appearances during White House press briefings have made him a household name and an unlikely celebrity . With his NIH-000096 straightforward demeanor and willingness to contradict President Trump, he's begun to develop the same kind of cult following as Supreme Court Justice Ruth Bader Ginsburg and former special counsel Robert S. Mueller Ill, who inspired countless "Plank like RBG" tank tops and a bizarre illustrated children's book, respectively . Even as whole swaths of the global economy collapse, the pandemic has created a robust cottage industry of Fauci-themed merchandise, including bottle openers, magnets and mugs. On Etsy, you can buy "Honk for Dr. Fauci" bumper stickers, prayer candles depicting "St. Fauci" and socks printed with Fauci's face. Graphic T-shirts bear slogans such as "I Need a Hero" and "In Dr. Fauci We Trust." If so inclined, you can even decorate your home with an "I Heart Dr. Fauci" throw pillow, or purchase a replica of Fauci's jersey from the time he captained the basketball team at Manhattan's Regis High School. Lingua Franca, which sells cashmere sweaters embroidered with resistance-fr iendly slogans for $380 and up, recently began taking orders for an army-green "Dr. Fauci Fan Club" knit. In honor of Fauci's Italian heritage, a clam bar in Long Island named a linguine dish after him this week . (Available for pickup only, "the linguine with white clam sauce shares origins with Fauci, as the sauce itself was invented in the Fauci Family's native Sciacca, Italy," the restaurant claimed in a statement.) As countless Americans remain glued to the news while trying to stay indoors, a robust Fauci fandom has flourished on line. On Facebook, the "Dr. Anthony S. Fauci Fan Club" has over 32,000 members. Thousands more congregate in groups with names such as "Dr. Anthony S. Fauci, the Man, the Myth, the Legend," "Dr . Fauci Speaks, We Listen" and "Dr. Fauci Memes for Social Distance Teens." An unassuming 79-year-old public servant who has advised six presidents, Fauci has become a "reliable constant in a time of uncertainty," The Washington Post's Ellen McCarthy and Ben Terris reported . But his admirers - and there are a lot of them - worry that it's only a matter of time before he's sidelined by Trump . When Fauci missed a White House news conference earlier this month, panic erupted on Twitter, along with speculation that he could be sick. There was palpable relief when he resumed his regular position at the podium the following day and appeared to hide some exasperation as Trump referenced "the deep state." Fauci later explained that he had simply been trying to dislodge a lozenge from his throat . But the much-analyzed "Fauci facepalm" had already become a meme, deployed by liberal members of what's known as the resistance. Fauci's newfound fame can be partially attributed to his willingness to engage with all forms of media - in recent weeks, he's gone on a Barstool Sports podcast, chatted with basketball star Steph Curry on lnstagram Live as Barack Obama listened in, and appeared on "The Daily Show With Trevor Noah." But it also undoubtedly helps that his fans tend to take social distancing seriously and consequently have ample spare time to produce fan art or perform songs written (or modified) in his honor . On social media, Fauci's virtual fan clubs peruse old photos of the infectious disease expert in search of "comfy turtleneck vibes," stitch his face on embroidery hoops and discuss erecting statues as tribute . They frost his name on cookies and joke about constructing shrines in his honor. Prominent activists and entertainers confess to wanting to marry him, or have him tuck them into bed. Fauci has remained characteristically modest about his new status as a cult figure. "Well, that's very nice," he responded when McCarthy and Terris mentioned that people all over the country were praying for him. Of course, that means that his fan base has only continued to grow. "I never met a guy that, worldwide, he is so loved," Semeraro, the Rochester doughnut shop owner,to ld CNN. "And a month ago, we never knew his first and last name." NIH-000097 Disclaimer: Any third-party material in this email has been shared for internal use und er fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessaril y represent my views nor those of NIAID, NIH, HHS , or the U.S. government. NIH-000098 (b)(6) From: Date: Wed, 1 Apr 2020 06 :26:32 -0400 To: DMID Word Nerds Subjec t : Fwd: Covid-19 comments on UK response Attachment s: image001.png , ATT0000l.htm, Covid19, UK pharmavaccine response .pdf, ATT00002.htm, Covid19, UK Urgent Action response.pdf, ATT00003.htm, VACCINEarticle.pdf, ATT00004 .htm Sent from my iPhone Begin forwarded message: F rom: Karl Simpson Dat e: Apri l 1, 2020 at 5 :46: 14 AM EDT To: "Fauci, Anthony (NJH/NIAID) [E]" Subject: Covid-19 comm ents on UK response (b)( ---------------- '> == (bH6J Dear Dr Fauci I was just re-reading your January 23 Viewpoint article in JAMA. So little time has passed, but so much has changed, and you r comments seem prescient. I have been working on emergent/ re-emergent infectious agents for some time, and authored a 2018 report for the UK government on vaccine responses that was summarised in a Vaccine publication last October attached . As almost everyone else, my attention has been redirected to Covid-19, although monkeypox remains a focus of my interest. You and your colleagues may be interested in two short documents I produced for the UK government on the 20 th and 22 nd of March. That also seems long ago now! As fellow citizen of our planet, I thank you and colleagues for your unstinting efforts to control infectious disease and Covid-19 in particular . Warmest wishes Karl NIH-000099 J. Karl Simpson CBiol FRSB CEO, JKSBioscience Limited .. .. ......... .. J Sbioscience NIH-000100 NIH-000101 JKSbioscience 2 Midanbury Court, 44 Midanbury Lane Southampton S018 4HF, UK Tel: _____ ___, (b) (6) Mobile: ------ (b) (6) Mail: (b)(6) Website: http://www.jksb ioscience.co.uk Skype: ----- (b)(6) (;ompany Numbe r: 10051396 VAT number: 238 0528 12 NIH-000102 From: Date: To: Subjec t : Att achment s: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Tue, 31 Mar 2020 21:07:00 +0000 NIAIDODAM FW: Additiona l data on masks MacIntyre BMJ.pdf, Figure 3.jpg Adding everyone since it wa s discussed in am meeting . thx From: Lerner, Andrea (NIH/NIAID) [El CbH6>> Se nt : Tuesday, March 31, 2020 5:04 PM To: Fauci, Anthony (NIH/NIAID) [El ------~= Cc: Folkers, Greg (NIH/NIAID) [E] (b)( >; Marston, Hilary (NIH/NIAID) [E] (b)(6) Eisinger, Robert (NIH/NIAID) [E] CbH6>>; Doepel, Laurie (N ._I_H-:/N_I_A__ ID""."" ) -:-[ E-:-: ] :.:::::====---=-..;., (b """ )~(6) Subject: Additional data on masks Dr. Fauci, In addition, I found the attachedd review on masks that addresses use in the community settings. Attached are the paper and figure 3, which summarizes the data from 9 very diverse RCTs(overlapping with what I had sent earlier) . Bottom line: generally there were not differences in Ill/URI/or flu rates when masks were used, although when early use and complian ce was taken into account, a few times a difference was seen. In addition: This case cont rol study noted tha t, among SARSpat ients in Hong Kong without a known source of infect ion, cases {27.9%) were less likely than uninfec ted controls {58.7%) to report wearing a mask fr equently in public , for what tha t's worth. https://wwwnc.cdc.gov/eid/article/10/4/03-0628 article (b)(5) Andrea NIH-000103 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:25:55 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Harvard Business School/ Wharton Business School Sent from my iPhone Begin forwarded message: From: A.rash Farin < arash @arash.tv> Date: March 30, 2020 at 10:32:04 PM EDT To: "Fauci , Anthony (N IH/NIAID ) [E]" (b)( > Subject: Re: Harvard Business School / Wharton Business School ------~~ Hi Dr. Fauci, I just wanted to confirm you received this . I also just read a great story on you in the WSJ, which discussed your amazing basketball and leadership skiJls when you were in coUege. Not surprisingly, even then , your teammates were seeking your advice on leading them through difficult times. Talk to you soo n. Regards, Ara sh On Sat, Mar 28, 2020, at 7:54AM, Arash Farin wrote: Hi Dr. Fauci, I'm a graduate of both Harvard Business School and The Wharton School, and have truly enjoyed watching the leadership you have shown our nation during these challenging times. Your steady hand, calm demeanor, incisive thoughts, and inteJlectual rigor, have aubeen quite comforting to us the last few weeks. I would like to see if you may have a few minutes to participa te in a webcast interview with myself and classmates from Harvard and NIH-000104 Wharton this coming week or next week. We would love to hear your thoughts on dealing with the coronavirus, lessons learned from other countries, and how we can prepare for a potential recuJTence, as has been discussed in the media , along with other topics you deem important. I may also be able to get students from Oxford University to join, as I attended there as well, and I know the UK is dealing with its own set of challenges. I look forward to hearing from you, and can be reached at ii. or via email (arash@ara sh.tv). ---- (b)(6) God bless you, and thank you for everyth ing you have been doing. Best Regards, Arash NIH-000 105 From: Date: To: Subject: delete (b)(6) Tue, 31 Mar 2020 07:24:50 -0400 DMID Wo rd Nerds Fwd: VVIP informat ion for diagnostic and therapy for COVI0-19- Kindly do not Sent from my iPhone Begin forwarded message: From: "anahar." Date: March 31, 2020 at 3:38:38 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" --------::-,--:=,(b)(6) Subject: Fwd: VVIP information for diagnostic and therapy for COVID-19Kindly do not delete Dear Sir We request you to spare a few minu tes to read this email. Abge nics is a life-sc iences company (Abgenics Life sciences Pvt Ltd, www.abgenics.in) based in Pune, India conducting pioneering research in the area of drug discovery using came lid antibody against infectious diseases in the past 10 years. Abgen ics Life Sciences was founded in 201 0 and is managed by Anil Nahar (Entrepreneur) and Dr Sanjib an K Bane1jee (Technical). Dr Banerjee has studied and lived in the USA for more than 7 y and worked in the area of infec tious diseases all his life. He has conducted extensive research in the area of camelid antibody technology in USA. After returning to India and with an urge to help the people of India in area of infectious diseases. Dr Banerjee in assoc iation with Ani l Na har started this ventu re. Since then, the company has extensively worked and developed novel camelid antibody technology for various infectious diseases causing bacteria (Multi drug resistant) and fungus like Pseudorno nas, Staphylococcus Aureus, Candida A lbicans and other NIH-000106 important pathogens . Our company is the only company in India working on Camelid antibody platform. Camelid antibody is a very robust and novel technology and can be used to develop drngs against any kind of antigen generated from bacteria and viruses. The specialty of camel antibody, it occurs in nanosize, high temperature and high Ph stable. It has very high affinity towards any antigen . A video explainin g our tec hnology is attached in the email. An Abgenics Life science was warded twice by - (b) (4) --------USA in the form of research projects to develop technology for (b) (4) NIH-000 107 (b) (4) ~b na virus is a spiked v irus and the sp ikes are used by the virus to first att ach i.to"\! , 1d then invade into the host cells. Subsequently the genetic materials, RNA at~ njected whe re it hijacks the host replication machinery to multiple and reinfec t more cells. If the initial attachment or the fusion of the vims and host membranes can be blocked, the virus replication cycle can be stopped, bringing the infection under control. The spike protein consists of two components, a globular head, S1 that helps the initial attachment and a spiral part S2 that is responsible for membrane fusion which forms the channel for the entry of the NIH-000108 (b)(4) Regards Anil Nahar MD Ab gen ies Life science s Pvt Ltd Kant Helix Bho ir Co lony Chinchwad Pune India Ph ----(b =>=c6) = NIH-000 109 From: Date: To: Subject: (b)(6) Tue, 31 Mar 2020 07:23:59 -0400 DMID Word Nerds Fwd: New biological disin fection automates, also effect ive against new Corona virus and multi -resistant germs, from a Florida Company Attachments: PastedGraphic-1.png, ATTOOOOl.htm, MSDS_Saniswiss_biosanitizer_aHP _P_rev_16032018.pdf, ATT00002.htm, br_automate_aH P_ HTA_EN.pdf, ATT00003.htm, br_ biosanitiz er aHP C_EN2.pdf, ATT00004.htm, ABSA conclusion Kopie.pdf, ATTOOOOS.htm,SHS_2308201 9_WEB.pdf, ATT00006 .htm Sent from my iPho ne Begin forwarded message: From: Alexa nder Friedrich Date: March 31, 2020 at 6:02:53 AM ED T To: "Fauci, Anthony (NIH/NIAID) [E]" (bH6J Cc: Tayfun Tay lor , "ceo@b iosan itize.us" Subject: New biological disinfection automat es, also effective against new Corona virus and multi-resistant germs, from a Florida Company -------~~ Dear Mr.Fauci, I know you're busy. But at this special time for all of us, I just need to write to you. The new Corona Virus is chang ing the world. It affects all of us in health, socia l and econom ic terms. The importance of hygiene and disinfection can be see n especially now in the andemic. (b) (4) NIH-000110 (b) (6), (b) (4) NIH-000 111 (b)( 4l do not hesitate to contact us. Yours, sincerely Alexander Friedrich Repr. Biosanitize USA Alexander Friedrich Repr . Biosanitize USA contact: a.friedrich@biosanitize.us Bio-San itize USA LCC 12601 New Brittany Blvd 33907 Fort Myers, Florida , USA tm ci..ner spaces. Slftr places. ✓ ✓ NIH-000112 ✓ ✓ ✓ From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Tue, 31 Mar 2020 02:07:49 +0000 Moshe Levi Graham, Barney (NIH/VRC) [El RE: Question from Georgetown Moshe: I am not sure that I can help you with this. I am referring your e-mail to Dr. Barney Graham of the NIAID VRC. Perhaps he can help you. Best regards, Tony ----------- From: Moshe Levi Date: Monday, March 30, 2020 3:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Ques tion from Georgetown (b)(6) ------~~ -------- (b)( > Dear Tony: I know that you are busy 7/24 with the current crisis. BUTI have a question for you or fo r one of your colleagues. (b) (4) Please let me know. Meanwhile there are not adequate ways to thank you for all you do. I should have seen that when you were my attending while you were at Cornell as a Visiting Professor Professor around Cb> <6> Moshe Cell: ----- (b)(6) Moshe Levi, MD Dean for Research Professor of Biochemistry and Molecular & Cellular Biology Georgetown University 3900 Reservoir Road NIH-000113 Med Dent NW 105 Wash ington, DC 20057 Office: Cb) (6) ---------- E-mail: (b)(6) NIH-000 114 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 31 Mar 2020 02:02:50 +0000 David Katz RE:COVID-19 ·- URGENT(Please do not disregard!) David: I know that it is you. I am sorry, but I am getting more than 2000 e-mails pe day. I to tally agree with you and this issue is being actively discussed as recently as today at the task Force meet ing. I am not sure what you mean by aerial "eradication" practically implemented. procedures that could be There are some data from NIH that indicate t hat mere speaking without coughing elicits aerosols that travel a foot or two. If that is the case, then perhaps universal wearing of masks in the most practical way to go. Best regards, Tony From: David Katz (b)(6)> Date: Monday, March 30, 2020 5:43 PM To: Fauci, Anthony (NIH/NIA ID) [E] (b)(6) Subject: Re: COVID-19 -- URGENT(Please do not disregard!) --------=:-:-= For God's sake, Tony -- this is me, not simply an unknown "messenger" from the general public! We go back together for many, many years (to our days together at the NIH , remember?). As you may recall, we worked (successfully) during the infamous 1969 "March on Washington", among other historically im octant events. Although I am now (b)(6) I continue to pay careful attention to world events, and this is one that exceeds any others that have occurred in our lifetime! As I wrote in my previous e-mail , I have become convinced that COVID-19 is behaving as an airborne virus, and, therefore, we should be directing our mitigation efforts toward mo re compr ehen sive aerial eradication procedures! Think about the most recent reports -- namely that imprisoned inmates, and a young baby, have recently been reported as "infected" with thi s virus. NIH-000115 Person-to-person infection in these circumstances is difficult to explain! But transmission by viable airborne virus could certainly happen! I look forward to your response, with best wishes, David David H. Katz, M.D. La Jolla, California On Sun, Mar 29, 2020 at 11:18 AM Fauci, Anthony (NIH/ NIAID) IE]______ Cb _H_6l'> wrot e: My work with the Coronavirus Task Force and the large volume of incoming ema ils precludes me or my staff from answering each individual message. I would encourage you to visit w ww .coron avirus.gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony 5. Fauci, M .D. NIH-000116 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 16:29:31-0400 (b)(6) Fwd: Hello from Canada! Could you pl ease respond to her for both of us. Thank s Begin forwarded message: From: "El-Gabalawy , Nadia (PHAC /ASPC)" -------------------- Date: March 30, 2020 at 2:48:41 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Hello from Canada! -------~~ (b)(6) (b)(6) Hi Dr. Fauci, I thought I would reach out to you amidst this crisis; I respect the work you're doing a great deal. (b)(6) Hani EI-Gabalawy, did a research sabbatical at NIH (b)(6) - Amazing work that you're doing. I've been following your discussions and scientific innovation regarding COVID-19. I've been working for the federal government in Intelligence for about thirteen years and recently moved to the Canadian Public Health Laboratory Netwo rk Secretariat to support the Emergency Operati ons Centre at the National Mic robiology Lab. I've been with the NML for almost my whole career. Just a quick hello and deep respect for your work. My colleagues and Director have said that we're on the exact same page as you, in terms of your perspective and assessment of the pandemic. Although there is a border between us, know that we are in agreement with your work and I'm thrilled to see you advising the public . There is no better person to do the job . Kindest regards, Nadia EI-Gabalawy Team Lead, Support Services, Canadian Network for Public Health Intelligence Public Health Agency of Canada/Government of Canada (b)(6) NIH-000118 Chef d'equipe, Services de soutien, Reseau canadien de renseignements sur la sante publique Agence de la sante pub lique du Canada/ Gouvernement du Canada (b)(6) NIH-000 119 (b)(5) -PCf NIH-000 120 Fauci, Anthony (NIH/NIAID) [E) Mo n, 30 Mar 2020 12:23:38 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subjec t : FW: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . From: Date: RSVPso rry no. From: Pinho, Paulo Sen t: Monday, March 30, 2020 8:18 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b "'"' ),,..,. (6): => Subject: Invitation to be the keynote speaker at an Insurance Medicine Conference in Washington, DC in October . Dear Dr. Fauci, I hope this email finds you wel l. It is abundantly obvious from the countle ss sifts through data and tallies of cases, interviews and press conferences, social media appearances, etc. that your schedule is crazy these days. As a practicing physician and an American, I am proud to be represented by you and th ank you for your efforts on our behalf. I realize with your schedule and with the t housands of emails, t his one may not make it, but I wanted to take a shot in the dark. I am currently the Chief Medical Off icer of a reinsurer and am on the planning committee for the American Academy of Insurance Medicine's annual meeting wh ich will be held in DC th is year October 18-21. Dr. Michael Osterholm had agreed to speak at the conference back in January as ou r first keynote speaker on the subject of pandemics, preparedness. I'd heard him speak before at Prudent ial (I was medical director there and we were a member company of CIDRAP)and his ta lk mirrored his book which I've also read. Regretfully, 2 weeks ago I received notice from Laurel, his EA, that he is unable to attend the meeting because he needs to travel to London that week for a meeting he is heading. I think that a talk on the topic is a must at any medical meeting and after hearing your pressers and coming to rely on your sage status updates and advice, coupled with the fact that the conference is in DC, I thought I'd give this a shot . Would you be AAIM's keynote speaker this year? In the midst of the current COVID-19 pandemic, we understand many industry conferences have had to be canceled. We are continui ng to closely monitor the trend of the COVID-19virus, and may have to do the same for the AAIM meeting in October, but if t here is an opportunity to gather and learn, we'd like to prepare for it . The audience is medical directors that work in the life, health, disability and longterm care space. Some are clinically active . Some of them are resources for health emergency planning fo r their com panies. The audience comes mostly from North America, although other countries/continents are well represented. The purpose of the meeting is really to illustrate novel trends in the industry that will likely impact morbidi ty and mortality in the near or distant future . We've had talks on CRISPR,marijuana, precision medicine, data analytics. They' re not hard core morbidity or mortality focused, but do touch on it . NIH-000 121 Given the scope of the meeting and the attendees and industries they represent, I think that a lecture on pandemics, bioterrorism and emerging infectious disease, especially in light of COVID-19, is necessary. I think you would teach new concepts to a team of doctors that would identify w ith some of the system gaps in our current supp ly chain and their impact on human health, wellbeing and survival. You'd provide experience and insight on what went wrong and what could be fixed in the future to make us collectively better prepared. We would be honored to have you speak and I'm glad to continue discussion of logistics with someone else on your team. If you needed more information about scope, I can certainly provide that. We do provide an honorarium and will cover travel and hotel expenses. Thanks so much in advance for any consideration you might give this request/offer and most of all thank you for your direction, demeanor and dedicat ion at this global time of crisis. Best, Paulo Paulo Bandeira Pinho , MD, FAAP, FACP Chief Medical Director OPTIMUM % RE INSURANCE COMPANY +1 214 528-2020, ext. 30984 ~ Paulo.Pinho@optimumre.com ----------(8} -----== 1345 River Bend Drive, Suite 100 Dallas, TX 75247, U.S.A. optimumre.com c:J I-~ OPTIMUM ~i, LifeReinsurance This ema il and its attachments is confidentia l and is inte nded only for the individual(s) to whom it is addressed . Distribution or copying of this ema il by anyone other than the named recipien t is prohib ited. If you receive this email in error, please not ify us by email and permanent ly delete this email and its attachments. NIH-000122 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:06:00 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Int erview w ith Or Anthony Fauci in The Times of London Sent from my iPhone Begin forwarded message: From: "Rivalland, Monique" Date: March 30, 2020 at 4:30:39 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Interview with Dr Anthony Fauci in The Times of London ------~~ Dear Anthony , I'm an editor at The Times of London. I'm gett ing in touch to discuss the possibility of interviewing you this week for our Saturday Interview slot next weekend. You have an incredibly tricky role in the fight against coronavir u s and have spoken with great clarity. We would love to speak to you about your position and predictions for America. The interview slot in question is the most prestigious in the weekend edition of The Times - a double-page spread reserved each week fo r the most influentia l indi viduals in pub lic life. Fo nn er interv iewees range from B oris Johnson to Jeremy Farrar. We would need 40 - 50 minutes of your time before Frida y morn ing, but preferab ly by Thursday even ing. The interview can be conducted over Skype/Goog le Han gouts/Zoom or whichever method of video chat you prefer. We would be delighted if you were to consider om request. Kind regards Monique Monique Rivalland Features Editor THE~ TIMES NIH-000123 (b)(6) @MoniqueLouiseR "Please consider the environment before printing this e-mail" This e-mail and any attachments are confident ial, may be legally privileged and are the property of News Corp UK &Ireland Limited on whose systems they were generated . News Corp UK & Ireland Limited is the holding company for the News UK group , is regis tered in England &Wa les unde r number 81701, has its registered office at 1 London Bridge Street, London, SE1 9GF and is registered with VAT number GB 243 8054 69. If you have received this e-mail in error, please notify the sender immed iately and do not use, distribute, store or copy it in any way . Statements or opinions in this e-mail or a ny attachment are those of the author and are not necessari ly agreed or authorised by News Corp UK &Ireland Limited or any member of its group . News Corp UK & Ireland Limited may monitor outgoing or incomi ng emails as permitted by law. It accepts no liability for viruses introduced by this e-mail or attachments . News Corp UK &Ireland Limited and its titles are committed to abiding by IPSO's regu lations and the Editors' Code of Practice that IPSO enforces . NIH-000 124 From: Date: To: Subject: (b)(6) Mon, 30 Mar 2020 06:05:28 -0400 DMID Wo rd Nerds Fwd: Chloroquine is a thromboxane inhib itor: there is a readily available analog Sent from my iPhone Begin forwarded messag e: From: "Dr. Josh Backen" Date: March 30, 2020 at 5:52:32 AM EDT ------~= To: "Fauci , Anthony (NIH/NIAID) [E]" (b)(6) Subject: Chloroquine is a thromboxane inhibitor: there is a readily available analog Dear Dr. Fauci, I'm (b) (6) internist. I have a sugge stion for 2 potent antiviral agent s, cheap and readily ava ilable, that may prevent viral shedding. No viral shedding? No infectivity. The concept is that EVERYONE should take these items. First a short bio: Dr. Josh Backon was affiliated with the Hebrew University Faculty of Medicine for over 33 years. He has a good track record (84+ publication s quoted by over 750 other researchers in jou rnal articles https ://scho lar. google. com/scholar?start =0&q=%22 backon ++j. %22& hl =en&as sdt= 0,5 and in over 250-300 texts as per https ://www.google.co m/search ?tbo=p& tbm=bks&q=% 22backon+j.+% 22&num = I 00 ) . In the 1980's he was Consulting Editor o f the Jomna l of Pediatric Endocrinology, Editor of Reviews in Pure and Applied Phann acological Sciences, and Associate Editor of the International Journal of Ado lescent Medicine and Health . From 1990-2004 , he was a consultant NIH-000125 on emergency planning and management at Israel's National Police Headquarters with Nitzav Mishneh Dannny Fisher. Chloroquine, an antimalarial drug, is now being used to treat Covid-19. Its mechanism was found in the 1970's to inhibit thromboxane https ://scholar. goo gle.com/scholar?hl=en&as sdt=0%2C5 &g=chlorogui ne+thromboxane&btnG = The problem with chloroquine was that it also elevated level of prostaglandin F2alpha. In 1980, Sriva tava, an Indian biochemi t working in Denmark found that GINGER i a potent inhibitor of thromboxane yntheta e. I wrote a number of paper in the 1980's on u e of ginger: htt :// cholar. oo le.com/ cholar?hl =en&as dt=0%2C5& =backon + mge r&btnG= - GINGER IS A POTENT ANTIVIRAL sdt=0%2C5& er+a - THE SECOND ANTIVIRAL AGENT IS TURMERIC [add black pepper since piperine dramatically increases oral bioavailability of turmeric) htt s://scholar. oo le.com/scholar?hl =en&as sdt=0%2C5& =turmeric + anti viral&og=tur Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin D Ting , N Dong, L Fang, J Lu, J Bi. .. -ACS Applied Nano ... , 2018 -ACS Publications ... These results offer theoretical support for the development of CCM-CDs as a hopeful antiviral drug for the treatment of coronavirus infections, including PEDV ... Curcumin (CCM) is a polyphenol compound obtained from turmeric roots ... NAC AND PIPERINE TO INHIBIT INFLAMMATORY CYTOKINES (iNOS, NF KappaB, TNFalpha) INVOLVED IN ARDS NIH-000126 Morta lity in COVID -19 patients is usua lly from ARDS (acute respirato ry distress syndrome) via inflammatory cytokines. Apart from N-acetylcysteine which was found 3 years ago to elevate atrial natriuretic factor [found by Kiemer in 2001 to zap inflamma tory cytokines: iNOS, NF KappaB, and TNFa lpha) now piperine in black pepper was found to inhibit inflamma tory cytoki nes [piperine also dramatically increases oral bioavai lability of turmeric [which has been used as a potent antiviral]: N-ACETYLCYSTEINE PIPERINE htt ://scholar. oo le.com/ cholar?h l=en&as sdt=0 5& - i erine%20i nflammatory%20cytokines&btnG =&fbclid = Iw AR0kXZxI66JPLFPry2 MDTDxOAe lgGnmBZdKBw7 c I v7 8Hfi7t0J Jnx0Y2zuE BTW the thromboxane hypothe i exp lain the increased male to female ratio in infectivity a we ll as the low incidence in younger people. http ://www .ncbi.nlm.nih.gov /pmc/article /PM 1433448/ Gut. 1987 Oct; 28(10): 1323. doi: 10.1136/qut.28.10.1323 PMCID : PMC1433448 PMID: 18668886 Ginger and carbon dioxideas thromboxane synthetase inhibitors:potential utilityin treating peptic ulceration Josh Backon NIH-000127 From: Date: To: Subjec t : Fauci, Ant hony (NIH/ NIAID) [E) Mon, 30 Mar 2020 02:06:21 +0000 Tim Boyd RE: You Rock! Nancy: Thank you for your kind note . Best rega rds , Tony ----- Orig inal Messag e----_...;::;.....----~~ From: T im Boyd (b) (6) ---------=.,...,-= Date: Sunday. March 29. 2020 8:53 PM To: Fauci, Anthony (NTH/NIAID)[E] Subject: You Rock! Cb)( Dea r Dr. Fauci, Atle r rea ding the article about you on the front of the New York Times this morn ing, 1 was dist resse d to learn that you have recently been negat ively targe ted via soc ial media by members of a certain US politica l factio n. The unfairness of these pers onal attacks upo n you is shocking, and I cannot imagine somet hing so bL11t ful happeni ng to someone like you who possesses such a depth of knowledge and unimpeachable integrity . You are the affable, truthful and reassu ring centre of calm during this de adly coronavirus storm. Your job is difficult enough without peop le taking verbal pot-shots every time you speak. 1 wish you all the best during this try ing time. Stay well (and I hope you don 't completely lose your voice , too) ! I loo k forward to seeing and hearing more from you on CNN and other media out lets. Best wishes, Nancy Hill (b)(6) Canada Sent from my iPhone NIH-000 128 NIH-000 129 NIH-000 130 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:31:58 -040 0 Auchincloss, Hugh (NIH/NIAID) [E];DMID Wo rd Nerds Fwd: Intro to Tony Fauci From party Hugh- I thought u responded to Carmona the former Surgeon general? Sent from my iPhone Begin forwarded message: From: Richard Carmona Date: March 29, 2020 at 9:42:33 AM EDT To: "Fauci, Anthony (NIH/NJAID) [E]" Subject: Fwd: Intro to Tony Fauci (bH6Ji Tony, first and foremost.. .. thank u for ur continued leadership and integrity in the" combat zone". I know u r drinking from the proverbial fire hose so I would not send anything ur way ifI didn't think it may have merit to address our current challenge with Coronavirus. I email introduced u to this group some time ago. Their science has advanced and in particular there seems to be a potential opportu nity to addres s the somet imes lethal " cytokine storm" in some coronavirus patients as described in the attached e mail. So I forward to you for your consideration as an adjunc t. On a daily bas is I receive numerous " ideas" to address coronavirus from many well intended people. A few have merit. Is there a Fed innovation review group that some of these potential ideas could be funneled too? I pray for you and your family Be well Rich Richard Carmon a 17th Surgeon General of The Un ited States Chief of Health Innovations Distinguished Professor University of Arizon a NIH-000131 8600 E. Rockcliff Road I Tucson, AZ 85750 CANYONRANCH. 0: 520 .749.7754 M: (b)(6) canyonranch.com B egin forwarded message: From: James Thacker Date: March 29, 2020 at 06:04:40 MST To: Richard Carmona Cc: Patricia Maxwell , "dgrange @osp reyg lobalsol utions.com" Subject: Intro to Tony Fa uci !ExternalSended Dear Rich, (b) (4) NIH-000132 I hope you and the family are healthy . As you can tell, I am still kickin ass and tak in names. DD Be we ll and be safe my Brother! DOL! Sine Pari, Jim James D. Thacker, PhD President/Founder - Head of Discovery &Science 1250 SussexTPKE, Unit 647 Mount Freedom, NJ 07970 Cell: (b)(6) Email: jim tha cker@therimunex.com URL: www.therimunex.com Privileged, confidentia l and/or copyright information may be contained in this e-mail. This e-mail is intended for the sole use of the addressee. If you are not the intended addressee, or the person responsible for delivering it to the intended addressee, you may not copy, forward, disclose or otherwise use this message, or any part of it in any way whatsoever, to do so is prohibited and may be unlawful. If you receive this e-mail by mistake, please advise the sender immediately by using the reply facility in your e-mail software . NIH-000 133 From: Date: To: Subject: (b)(6) Sun, 29 Mar 2020 11:25:38 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Phone Intervie w - COVID19 Sent from my iPhone Begin forwarded messag e: F rom: "mton-es8@ myse neca.ca " Dat e: March 29, 2020 at 11:06:49 AM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)(6) Subject: RE : Phone Inter view- COVID19 -------~~ Hi Dr. Fauci, I' m look ing to do a qu ick 10 minute phone interv iew on COVID-19. I've seen your interview s on CNN and they are very informat ive so I think you would be perfect for our podcast. Th is wou ld be fo r a podcast available to faculty and stude nts at Seneca Media Depa rtment in Toronto . Thanks, Mon ika To rres www .sen ecajoumalism.ca NIH-000 134 (b)(6) From: Date: Sun, 29 Mar 2020 11:24:55 -040 0 To: DMID Word Nerds Subject: Fwd: URGENTATTN DR FAUCIRE:COVID-19 IDEAFROMAUSTRALIANGP! Please just read and see it this has the merit I believe it does!! Sent from my iPhone Begin forwarded message: From: Stevie Date: March 29, 2020 at 11:18:55 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) Subject: URGENT ATTN DR FAUCI RE: COVID-19 IDEA FROM AUSTRALIAN GP! Please just read and see it this has the merit I believe it does!! ---------=-=--:-= Dear Sir, My OP friend, Dr P'ng is a genius. He has a radical idea for fighting COVID- 19. P lease find his idea , petition, projections and research attached to th e petit ion. I told him he needed to get this is front of you and Bill Oates . Please cons ider it. I believe it is viable and the best shot we have . I know you are the expert but I think this is viable way we can help save millions of lives! Yours sincerely, Stephanie Stephanie Russell-Farnham Founder &CEO EmpowerME Enterprises M (b)(6) E stevie@empowerme .enterprises https: //www.cha nge .org/p/world-health-organisation-belp-defeat-covid19-save -theworld?recruiter= 1066780682&utm somce=shar e petition&utm rnediu m=facebook&utm campaign=share petition&utm term=share petition &recmited by id=40795060-7lab-llea-a9:f813e6b487f548&utm content =starter 1b share content en-au%3Avl 1 NIH-000135 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sun, 29 Mar 2020 11:23:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: New Zealand interview request To: Subjec t : fyi From: Pat Brittenden Date: Sunday, Marc h 29, 2020 7:21 AM --------, .....,..,= --------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: New Zealand interview request (b)(6) Hey Dr Fauci, Am wondering if you would be interested in having a chat with us in NZ, over Zoom, as we all sit in our houses fighting Coronavirus I do a podcast which is normally live streamed but we currently have a country wide lockdown and lots of us have moved our gear home to continue providing content for people who are stuck in their homes the US is like out big brother, we love you guys and would like to connect in solidar ity about COVID19 so I'm hoping that maybe you could find us sometime to have a chat over the internet . Some content would also help us give some more content to Kiwi's who have gotten to the end of Netf lix ;) Find out more about the podcast at www.theDOC.nz and more about me at www.patbrittenden.com/about Can make anytime happen, fingers crossed we'll hear back from 'someone'. Pat Brittenden www.theDOC.nz www.patbrittenden.com/about (b)(6) NIH-000 139 From: Date: To: Subject: irinotecan+etoposide (b)(6) Sat, 28 Mar 2020 19:01:58 -0400 ldonae Lovetrue Re:COVID-19 aetiology and treatment for critically ill patients: Thank you for your note AS Fauci Sent from my 1Phone On Mar 28, 2020, at 6:36 PM , Idonae Lovetrue wrot e: Dear Dr. Fauc i, In addition , I'd like to share with you the following clin ically relevant genetic differences between patients in the US and in East Asia: (b) (4) Please find attached dosage recomme ndation and my team is standing by if you need any further assistance. Sincerely, ldonae ldonae Lovetrue I CEO, Demiurge Technologies AG, Switzerland www . demiurge .technology This email and any attachments thereto may contain private, confidential, and privileged material for the so!e use of the intended recipient. Any eview. copying, or distribution of this email (or any attachments thereto) by others 1sstnctly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto. This email is intended for information purposesonly and is provided without any warranty of any kind, either expressed or implied. While some information used on th1s document may have been obtained from NIH-000140 va,1ouspublished and unpublished sourcesconsidered to be reliable, Dem:urge 1echnologiesAG neither guarantees its accuracy or completeness nor accepts iabil1ty for any direct or consequential losses arising from its use.Thank you. From: Idonae Lovetrue Date: Saturday , 28 March 2020 at 15:53 To: Cb>< Subject: COVID-19 aetiology and treatment for critically ill patients: irinotecan +etoposide Dear Dr. Anthony S Fauci, This is ldonae , CEO at Demiurge Technologies AG, a Swiss Albiopharma company making accurate and rapid drug discoveries for diseases with limited available clinical data. We are committed to the non-profit dissemination of our COVID-19 discoveries to the public to facilitate the search for COVID-19 effective treatments. SARS-CoV-2 is fundamentally different from all the other viruses that the world has hitherto known, so treatments must be rationally designed to avoid fueling the adaptive mutation and the latent infection of SARS- CoV-2. Demiurge is the world's first company that has discove red the detailed aetiology of COVID -19 that consistently explains the clinical features of COVID-19 and the MoA-based scientific rationale of the candidate treatments for COV ID-19 (https://www.preprints .org/manuscripV202003.0341 /v1 ). (b)(4l NIH-000141 (b) (4) Thank you for your consideration and my team is stand ing by for any furt her assistance . Sincerely , ldonae ldonae Lovetrue I CEO, Demiurge Technologie s AG, Switzerland NIH-000142 www.demiurg e.technology This email and any attachments thereto may contain private, confidential, and privileged material for the sole use of the intended recipient. Any review, copying, or distribution of this email (or any attachments thereto) by others is strictly prohibited. If you are not the intended recipient, please contact the sender immediately and permanently delete the original and any copies of this email and any attachments thereto . This email is intended for information purposes only and is provided without any warranty of any kind, either expressed or implied. While some information used on this document may have been obtained from various published and unpublished sources considered to be reliable, Demiurge Technologies AG neither guarantees its accuracy or completeness nor accepts liability for any direct or consequential losses arising from its use.Thank you. NIH-000143 From: Date: To: Cc: (b)(6) Sat, 28 Mar 2020 17:58:32 -0400 Hallett, Adr ienne (NIH/OD) [E] Collins, Francis (NIH/OD) [E];Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie (NIH/OD) [E];Shapiro, Neil (NIH/OD) [EJ;Lauer, Michael (NIH/OD) [E] Subject: Re: Brad Sherman Thanks to everyone. On Mar 28. 2020, at 5:32 PM , Hallett, Adrie nne (NIH/OD) [E] (b) (6J>wro te: Thanks Franc is. I just spoke to his Deputy Chief of Staff ________ (b_H _6) (b) (5) I'll share what I see when I see it. Adrienne On Mar 28, 2020, at 2:27 PM, Collins, Francis (NIH/OD) [E] (b)( t: Hi Adrienne, NIH-000 144 I spoke with Brad Sherman (D-CA) yesterday . He had origi nally reached out to Tony, and Cliff Lane spoke to him Thursday, but I stepped in to try to lift one task off of Tony's plate . (b) (5) He said he is sending a letter to Tony and me, asking what we need to go flat out against COVID-19. He wanted to know who from my office his staff could work with. I said you! Francis NIH-000 145 From: Date: To: Subjec t : (b)( 6) Sat, 28 Mar 202017 :31:25 -0400 Jiaxian Zhou Wu Re: Thank you for your service! Many thanks for your kind note. > On Mar 28, 2020, at 4:40 PM, Jiaxian Zhou Wu > ------------ (b) (6) wrote : > > Dear Dr.Fauci, > > I am writ ing this emai l to personal ly thank you for your invaluable service to our country. The United States of America. Th is virus, COVTD-19 , is really dangerous and Jam very scared of it. Tam really worried about my country , about the count less deaths . Your advice to the president has proven rea lly important to preve nt the spread of the disease , however, in this nation, there is another epidemic based on lies and self~interest, now the people behind the fake news are targeting to you, one examp le is the post of an ema il that relates to you with the fonne r Secretary of State, Hillary Clinton. This is why l decided to write a letter of support, I am sick of fake news ,personal attacks and violation of the First Amen dment , the 1ight to have an opinion,to civil servants serving this country. > > I am still young but I still want to live in a United country. I ask you to continue your job, I want you to know that most Americans regardless of ideology are grateful of your service and sacrifice . A virus does not understand boundaries nor ideology , I am not an expert on this topic nor the presiden t and pol iticians. Please guide us with the truth in these dire and dark days . NIH-000 146 From: Date: ----- (b)( 6) (NIH/N IA ID) [E) Sat, 28 Mar 2020 19 :43:52 +0000 (b)( To: Subject: RE: medRxiv: Ant i-hypertensive Angiotens in II receptor blockers associated to mitig ation of disease severity in eld erly COVID-19 pati ents (b)( 6) Thanks for the note. (b)(6) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Date: ----------------27, 2020 2:37 Friday, March (b)(6b PM -------~~ --------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subje ct: Re: medRxiv: Anti-hyper tensive Angiotensin II recep tor b lockers associated to mitigation o f disease severity in elderly COVID-19 patients Hi Tony, NIH-000147 Thanks for the update. A ll of th is early science is certai nly confusi ng - (b)(6) Much t he same th in g t hat we are hear ing from Am Colle ge of Card iology . I appreciate How are you do i ng? your keeping me informed. (b)( 6) Best , ~ (b)(6) From: Fauci, Anth ony (NIH/N IAID) [E] Date: Friday, M arch 27, 202 0 1:29 PM (b)(6) > To: Subject: [EXTERNAL)FW: medRxiv: Ant i-hyp ert ensive Angiot ensin II receptor blockers associated t o miti gat ion of disease severity in eld erly COVID-19 pat ient s --------- ---------------- ** ATTENTfON: This email originatedfrom outside the MedStar network. ** DO NOT CLlCK links or attachments un less you recognize the sender and know the content is safe. )(6): See below. The situ ation continu es to get more comp licated . Best , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui ld ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)( 6) FAX: (301 496 -4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Yingxia Liu, Feng ming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Mengli Cao, Zhaoqin Wang, Xiaoh e Li, Shaogeng Zhang, Lu Ye, Jingjun Lv, Jie Wei, Tuxiu Xie, Hong Gao, Kai-Feng Xu, Fusheng Wang, Lei Liu, Chen gyu Jiang NIH-000148 doi: https:Udoi.org/10.1101/2020.03 .20.20039586 This article is a preprint and has not been certified by peer review [what does this mean?]. It re orts new medical research that has et to be evaluated and so should not be used to uide clinical practice. • Abstr act • Info/H isto ry • Met rics • • • Preview PDF Abstract Summary Background The novel coronav irus (CoV) severe acute respiratory syndrome (SARS)-CoV -2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countr ies. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor . Indeed, it was reported that the balance of Renin-Angiotensin System (RAS), regulated by both ACEand ACE2,was altered in COVID-19 patients. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI)and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertens ion comorbid ity. The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB),beta blockers (BB), or th iazide to treat preexisting hypertens ion prior to the hospital were compared to patients who did not take any of those drugs. Methods In this multicentre retrospect ive study, clinical data of 511 COVID-19 pat ients were analyzed. Patients were categor ized into six sub-groups of hypertens ion como rbidity based on treatment using one of anti -hypertension drugs (ACEI,ARB, CCB,BB, th iazide), or none. A meta -analysis was performed to evaluate the use of ACEI and ARB associated w ith pneumonia using published stud ies. Findings Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% Cl 0.128-0.916, p=0.025) . The meta -analysis showed that ARB use has positive effects associated with morb idity and mortality of pneumon ia. Interpretat ion Elderly (age>65) COVID-19 patients with hypertension comorb idity who are tak ing ARB anti -hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti -hypertens ion drugs . Funding Nationa l Natural Science Foundat ion of China, Chinese Academy of Medica l Sciences Di claimer: Any third-party material in thi email has been hared for internal use under fair use provisions of .. copyri0 ht law, without further verification of it accuracy/veracity. It docs not ncccs arily reprc ent my views nor th ose of IAID , NIH H H , or th e U. . governm ent. MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region Nationally recognized for clinical quality in heart, orthopaedics, cancer and GI IMPORTANT: This e-mail (Including any attachments) may contain information that 1sprivate, confidential, or protected by attorney-client or other privilege. If you received this e-mail in error, please delete it from your system without copying it and notify sender by reply e-mail. so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000149 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 19:26:52 +0000 Real. Francisco RE:A thank you note Paco: Thank you for yo ur kind not e. Warm regards, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectiou s Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mai l (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform t he sender and delete it from your mailbox or any other storage devices . The Nat ional Ins t itute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of t he NIAID by one of its representa t ives . From: Real.Francisco Sen t: Saturday, March 28, 2020 3:20 PM To: Fauci, Anthony {NIH/NIAID) [E]------Subject: A thank you note --------- ~= (b)(6) Dear Tony, please allow me to call you Tony as I feel somewhat close to you (although there is no reason why you should rem ember me). In early 19811 was doing a clini cal fellowship in Immunology/Oncology at Memorial Sloan-Kettering Cancer Center and wrote to you (b) (6) During my period at Memorial I worked extensively on AIDS and Kaposi's sarcoma ... and eve r since - I moved in 1988 to Spain, my home country - I have followed and admired your wo rk. ----------------------- (b)(6) I always felt close to you and your amazing work . Now, when I see you taking care of your coun t ry's action against Covid-19, I am proud to have been attracted and inspired by your work in biomedical research and I am proud of what we physician-scientists - can do for your societies and fo r human beings . NIH-000 150 From my very modest end as a human being, thanks for your responsib le, honest, scientific leadership. Best wishes, we need people like you Francisco X. Real (Paco) Epithelial Carcinogenesis Group Molecular Oncology Programme Centro Nacional de lnvestigaciones Oncol6gicas Melchor Fernandez Almagro, 3 28029-Madrid (Spain) Phone +34 917328000 ext 3660 E-mail preal@cnio.es www.cnio.es HAZTE AMIGO/A DEL CNIO Fb Hazte Amigo de\ CN\O I Tw @HazteAmigoCNIO mas INVESTIGACl6N menos I Youtube CANCER canalcnio ** ADVERTENCIALEGAL**: Este correo electr6nico, yen su caso los fichero s adjuntos, pueden contener informaci6n protegida para el uso exclusivo de su destinatario. Se prohfbe la distribuci6n, reproducci6n o cualquier otro tipo de transmisi6n por parte de otra persona que no sea el destinatario. Si usted recibe por error este correo, se ruega comunicarlo al rem itente y borrar el mensaje recibido. 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Your personal details will not be passed on to anyone else unless you authorise us to do so or we are required to do so by law. You may exercise your rights regarding access, rectification, suppression, limitation of processing, portability and opposition by writing to the following address: c/Melchor Fernandez Almagro 3, 28029 (Madrid). You may contact the Data Protection Delegate (Delegado de Protecci6n de Datos) at: delegado lopd@cnio.es. If you require further information about the processing of your personal data, go to the follow ing link on our webpage : https://www .enio.es/ es/privacidad/index. asp NIH-000152 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Sat, 28 Mar 2020 19:00 :32 +0000 To: Auchincloss, Hugh (NIH/N IA ID) [CJ (NIH/NI A ID) [E];McGowan, Robert (Kyle) (CDC/OD/OCS) Cc: (b)(6) ---------- Subject: Attachments: (b)(6);Harper, Jill FW: Time -Sensitive OSTPRequest - Due 12 pm Monday , March 30 2020-03-28 _ COVID-19 FOAs-Projects .xlsx Pleaserespond Anthony S. Fauci, MD Direc;tor National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representa t ives. From: Schwetz, Tara (NIH/OD) [E] Date: Saturday, March 28, 2020 2:57 PM To: ICDDIR-L@list.nih.gov (b)(6) > Cc: List DEPDIR-L; NIH Director's Executive Committee ; NIH P&E Principals and Alternates ; Wa lsh, Elizabeth (NIH/OD) [E) (b)( > Subject: Time-Sensit ive OSTP Request· Due 12 pm Monday, March 30 Importance: High Good afternoon, We received a time -sensit ive request from OSTP that we are asking for your help to comp lete . Apo logies in advance for the short turn -around . Action - Complete t he attached template to provide FOAs and projects on " innova tio n" and COVID-19, specifically focus ed on the topics described below . If your ICO has no noth ing to report, please let us know . Requestor - OSTP NIH-000153 (b)(5) POCs and Due Dat e - Please send the completed template to Elizabeth Walsh (Elizabeth.walsh@nih.gov) by noon on Monday, March 30 Timeline - NIH Receipt Date Institut e Response to OD Due Date OD Office Review Date NIH Final Response Due Date 3/28/20 3/30/20 3/30/20 3/30/20 Additional Instructions - • I pulled all the COVID-19 FOAsfrom the Guide; however, I did not sort through which ones are relevant to this request. Please submit only those that your IC is the lead on that meet the criteria listed above. Delete any that do not apply. Attachment s - • Response template (FOAs tab, Grants-Contracts tab) Do let me know if you have any questions. Best, Tara A. Schw etz, PhD Acting Director, NINR Associate Deputy Director, NIH A: Building 1, Room 138 P: (b)(6) I M: (b)(6) --- ~-,=, NIH-000154 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202018:43:17 +0000 Date: (b)(6) To: Subject: FW: Washi ngtonian : You Can Now Buy Ant hony Fauci Swag Geeeez Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------- (b) ~ > From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6 :11 PM To: NIAID OD AM ; Subject: W ashingtonian : You Can Now Buy Anthony Fauci Swag ------------------- (b)( You Can Now Buy Anthony FauciSwag T-shirts, mugs, pillows-and, yes, even a Fauci prayer candle. Wr itten by Daniella Byck I Published on March 27, 2020 NIH-000 155 About Coronavirus 2020 Washingtonian is keeping you up to date on the coronavirus around DC. More from Coronavirus 2020 Fauci stans, assemble! Dr. Anthony Fauci,director of the National Institute of Allergy and Infectious Disease, has emerged as the celebrity of th e coronavirus crisis. Like others before him (remember Mueller mania?), his prominence has yielded but tons , t-shirts, and gifts, all flaunting the Fauci. NIH-000156 Fauci face socks Another reason you won' t want to wear your shoes inside. $9.99, Etsy. NIH-000 157 "Dr. Anthony Fauci Fan Club" button Fauci-fy any look with this pin. $3 .16, Etsv. NIH-000 158 "I need a hero" T-shirt Paying homage to Fauci and Bonnie Tyler? This shirt is working overtime . $19.99, Etsv. NIH-000 159 "Honk for Dr. Fauci" lawn sign A social distancing win: Show your support without leaving the house. $14 .95, Etsy. NIH-000 160 FauciPrayer Candle Praying you washed your hands . $20.20, Etsy. NIH-000 161 "Fauci 2020" T-shirt Finally, a shirt for those White House coronavirus briefings. $18, Etsy. NIH-000 162 "Hope" sweatshirt Thanks, Fauci. $18.99, Amazon . NIH-000 163 KEEP CALM AND WASH YOUR HANDS "Keep calm and wash your hands" mug A little PSAto go with your morning coffee. $19.95, Etsy. NIH-000 164 Dr. Anthony Fauci T-shirt A perfectly acceptable day-to -evening look in your self-quarantine. $29.00, Esty. "I Heart Dr. Fauci" throw pillow For sweet, scientific dreams. $20.66, Redbubb/e . Keep Up on DC' s Latest Fashions with Our Shopping Newsletter Fashion finds and deals, and the latest trends for you and you r home. Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-000 165 Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 2020 18:26:42 +0000 From: Date: To: Subjec t : (b)(6) FW: Wpost : How the Viet nam War may have changed Anthony Fauci's life FYI Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers , Greg (NIH/NIAID) [E] Date: Friday, March 27, 2020 6:15 PM Subject: Wpost: How the Vi etn am War may have changed Anthony Fauci's life Opinions How the Vietnam War may have changed Anthony Fauci's life nthony S. Fauci, director of the National Institute of Allergy and Infectio us Diseases, speaks with th e coronavirus task forc e at th e Wh ite House on Tuesday. (Jabin Botsford/The Wash ington Post) By Ray Greenberg March 27, 2020 at 3:34 p.m . EDT Ray Greenberg is a physician epidemiolog ist, former executive vice chancellor for health affairs at the University of Texas System and the author of "Medal Winners: How the Vietnam War Launched Nobel Careers." NIH-000 166 Americans may have the war in Vietnam to thank for Anthony S. Fauci. An adviser to six presidents and now the trusted public face of the scientific response to the coronavirus pandemic, Fauci has worked at the National Institutes of Health (NIH) for more than a half-century beginning in 1968 with a group of doctors cheekily known as Yellow Berets. During the conflicts in Korea and Vietnam, the U.S. military faced a pressing need for physicians. In 1966, during Fauci's senior year at Cornell University Medical College, a military recruiter came to tell the assembled students: "After you finish medical school, every one of you except the two women will either be in the Air Force, the Army, the Navy, or the Public Health Service." The last option, entering the Public Health Service, entailed assignment at the NIH, the Centers for Disease Control or the Indian Health Service. Those who were selected to serve at the NIH were known officially as clinical associates, but informally they were referred to as Yellow Berets. Whether the designation was born in jest or derision, it was intended as a foil to the Green Berets of the Army Special Forces. Fauci never liked the label because it implied an unwillingness to serve in harm's way. "As a physician," Fauci said, "I felt if I had to go [to Vietnam], I would gladly do my part to try to help." The competition for the limited number of Yellow Beret slots was so intense that only the best and brightest young physicians were selected. Fauci, the top graduate in his medical school class, was one of seven chosen from 140 applicants to train in his laboratory of interest. As described in my book "Medal Winners: How the Vietnam War Launched Med ical Careers," the class of Yellow Berets that entered with Fauci included four future Nobel laureates : Joseph Goldstein, Michael Brown, Harold Varmus and Robert Lefkowitz . Each new appointee completed two years of clinical training before arriving at the NIH. Their primary responsibility was learning how to conduct basic research under the guidance of a senior scientist. The second job was to care for patients at the NIH Clinical Center. Fauci and his fellow infectious disease colleagues also helped to care for wounded service members at the nearby National Naval Medical Center. Fauci, who had some research experience in medical school, trained at the NIH for three years under the tutelage of Sheldon Wolff - a pioneer in the relationship between the immune system and infectious diseases. Following a year of additional clinical training back in New York, Fauci returned to the NIH as a senior scientist conducting pioneering work, first on autoimmune conditions, then transitioning to study the newly emerging disease that would become known as AIDS. When he entered the clinical associate program, Fauci's ambition was to become a medical school professor. Had the Vietnam War not brought him to the NIH, Fauci probably would have remained in academia and the country never would have benefited from his extraordinary public service. Instead, from his position as director of the National Institute of Allergy and Infectious Diseases, Fauci has helped shape national policies related to HIV, bioterrorism and a series of pandemic threats including avian influenza, H1N1 (swine) influenza, Ebola and severe acute respiratory syndrome. It is hard to imagine any other physician who has had such a sustained and profound impact on the health of our nation. While Fauci remained at the NIH for his entire professional career, most of his fellow Yellow Berets left Bethesda after their training was completed and headed for jobs at universities . Across the nation, the former Yellow Berets became medical school scientists, department chairs and deans. More than 60 former clinical associates, including Fauci, were elected to the prestigious National Academy of Sciences, and he also was one of the more than 125 Yellow Beret alumni elected to the Institute of Medicine (now the National Academy of Medicine). In addition, Fauci was one of 10 alumni to receive the National Medal of Science. NIH-000167 For all the scars left by the Vietnam War, we should not overlook the fact that in its absence, SOyears late r the country would probably not have Anthony Fauci guiding us through our current crisis. Dr. Fauci, we salute you and your fellow Yellow Berets. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIATD , NTH, HHS , or the U.S. governme nt. NIH-000168 From: Fauci, Anthony (NIH/N IA ID) [E) Sat, 28 Mar 202017:52:04 +0000 Billet, Courtney (NIH/N IAID) [E] RE: Dr . Fauci hits and requests Date: To: Subject: Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------------- ~= -------- From: Billet , Courtney (NIH/NIAID) [E] Se nt : Friday, March 27, 2020 6:24 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Stover, Kathy (NIH/NIAID) [E] (b) (6) > (b) (6)> (b)( ·>; Conrad, Patrici a (NIH/NIA ID) [E] (b)(6)>; Routh, Jennifer (NIH/NIAID) [E] Subject: FW: Dr. Fauci hits and requests (b) (5) From: Billet, Courtney (NIH/NIAID) [E] Date: Friday, Ma rch 27, 2020 6:23 PM To: O'Malley, Devin M. EOP/OVP Subject: RE: Dr. Fauci hits and requests ---------~~ (b)(6) •> (b) (5) Devin- Cb)(5l --------- From: Routh, Jennifer (NIH/N IAID) [E) Date: Friday, March 27, 2020 6:18 PM NIH-000 169 (b)(6) To: O'Malley, Devin M . EOP/OVP~--:-:---:-::-:-::-::-:-".".'":""::--:.:==::.;__.;._......;. (bH ; Love, Kelly__ A. EOP/OVP ..;___,:-:-=, (b)(6)>; Henning , Alexa A. EOP/WHO (b)(6)>; Bowman, Lauren K. EOP/WHO (b)(6); Porter , Macaulay V. EOP/OVP __ ___;___; ___ .....;._~ (b~)( ~6)'> _________ _ --------- Cc: Billet, Courtney (NIH/NIAID) [E] (b)( ; Stover, Kathy (NIH/NIAID) [E] (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill ":"----:-----:--:::====~~~= (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) (b)( > Subject: RE: Dr. Fauci hits and requests Thanks, Devin. We have declined and scheduled as you advised. Below is an updated list and schedule . Friday 3/27 • Pittsburgh, PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit completed • Baton Rouge, LA- Morning News w/ Brian Haldane - 7:05 am live hit completed Saturday 3/28 Showtime Desus and Mero - taping at 2 p.m. scheduled Sund ay 3/29 CNN State of the Un ion - live hit 9: 15 a .m . scheduled Monday 3/3 0 • Apple TV+ Oprah - tape 11:30 a.m. scheduled • Radio - Rantz show Seattle - 8 p.m. live hit schedule d • Radio - John/Ken show California - 8:30 p.m. live hit scheduled Tuesday 3/31 • CBS T he Late Show with Step hen Colbert-tape 11 a.m . schedule d • CNN Coro navir us podcast with Sanjay Gupta - tape 12 noon sche duled • Wall Street Journa l T he Journa l Podcast - tape 1 p.m . ET - Wedne sday 4/ 1 New York Times The Daily podcast- tape 12 noon schedu led (b)(5) Thanks, Jen Jennifer Routh [E] NIH-000 170 News and Science Wr iting Branch Office of Commu nications and Govern ment Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimor : The information in this e-mail and any of its attachments is confidential and may contain sensi tive information. It should not be usedby anyone who is not the original intendedrecipient. If you have received this e-mail in error please inform the senderand delete it fromyour mailbox or any other storage devices. The National Institute of Allergyand Infectious Diseases shall not accept liability for any statements made that are sender's own and not expressly madeon behalf of the NIAID by one of its representatives. J:rom : O'Mall ey, Devin M . EOP/OVP -------------- Date: Thursday , March 26, 2020 6:58 PM To: Routh , Jennifer (NIH/N IAID) [El-------=-:~ (b)(6) >; Love, Kelly A. EOP/OVP ---------- (b)(6)>; Henn ing, Alexa A. EOP (b)(6) 6ow man, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP (b)(6)> Cc: Billet , Courtn ey (NIH/NIAID) [E] -------~ = (b)(6); Stover, Kathy (NIH/NIAID ) [E] Cb H 6); Conrad, Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6) Mu rphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests CbH6J; Hall, Bill "':":'":':-:-:--:-:-::::-:--:.=====---,.,_.; =- (b)(6) Yellow means schedule Green means let's revisit Crossed out means please decline From: Rout h, Jennifer (NIH/NIA ID) [E] Se nt: Thursday , March 26, 2020 6:52 PM --------- (b)(6) ----------~~ >; Love, Kelly A. EOP/OVP -:-----:-:-----:--::--:-::-7."'.'"'.".'":""'.'.-.:===:...;_-_.;. _ _;___ To: O'Malley, Devin M. EOP/OVP ----------- (b)( (b)(6); Henning , Alexa A. EOP/WHO Bowman, Lauren K. EOP/WHO ___ .;__ ____ ...;_ _ ------~ (b)(6); (b)(6J> ; Porter , Macaulay V. EOP/OVP _,(~ b)~(6) ~> ----------- Cc: Billet , Courtney {NIH/NIAID) [E] ...;,.._--=-~ = (b)(6)>; Stover, Kathy (NIH/NIA ID) [El "':":'":':-:-:--:-:-::::-:--:-;:::===::!....:-~ ~ (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subjec t : RE: Dr. Fauci hit s and requests Cb H 6J>; Conrad, Patri cia (NIH/NIAID) Good even ingBelow is a list of pending hits and requests for Dr. Fauci: Thur sday 3/26 • W TOP- 6:10 a.m . completed • NPR Morn ing Ed ition - 7 :07 a.m . co m pleted • YouTube content creato r inte rviews - 11 a .m . completed . NIH-000171 [El o The content creators will publish the interviews on YouTube over the next few days. We expect Trevor Noah will publish tonight. • lnstagram Live video with Steph Curry- 1 p.m. completed • CNN Town Hall- scheduled 8 p.m. live Friday 3/27 • Pittsburgh , PA (also airs in OH and WV) - Bloomdaddy radio - 634 am live hit scheduled • Baton Rouge, LA - Morning News w/ Brian Haldane - 7:05 am live hit scheduled (b) (5) NIH-000 172 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attach ments is confide nti al and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sende r and delete it from you r mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sende r's own and not expressly made on behalf of the NIAID by one of its representatives. ---------------------~~ From: O'Malley, Devin M. EOP/OVP Date: Wednesday, March 25, 2020 9:24 PM (b)(6) To: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Love, Kelly A. EOP/OVP (b)(6 b ; Henning , Alexa A. EOP/WHO (b)(6) ; Bowman, Lauren K. EOP/WHO (b)(6) ; Porter , Macaulay V. EOP/OVP ----------- (b)(6 )> Cc: Billet , Courtney {NIH/NIAID) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia {NIH/NIAID) [E] (b)( >; Hall, Bill (HHS/ASPA) (b)(6J>; Mu rphy, Ryan (OS/ASPA) (b)(6)> Subject: RE: Dr. Fauci hits and requests "'.'----:-----:-::====-..:_~~ (b) (5) From: Rout h, Jennifer (NIH/NIAID) [E] _______ Date: Wednesday, March 25, 2020 5:07 PM To: O'Malley, Devin M . EOP/OVP.__ _________ (b)_ (_ 6)> ------------=-:-:= (b_) _ <; NIH-000173 Love, Kelly A. EOP/OVP (b)( Henning, Alexa A. EOP/WHO ----------Bowman, Lauren K. EOP/WHO (b)( ___ ____ (b)( 6) > ,:___~:;;----------- ,:__ (b)(6) ; >; Porter, Macaulay V. EOP/OVP Billet, Courtney (NIH/NIAID) [E] _____ --,;;(b-,-. H=6); Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Hall, Bill "'.".-"'~~~=====-.;;__ ~= (HHS/ASPA) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6) Subject: RE:Dr. Fauci hits and requests Cc: -------- Good eveningBelow is a list of pending hits and requests for Dr. Fauci. Flagginga few new inquiries: (b) (5) W edne sday 3/25 • Bob Rose Radio Show - Ga insville Fl - 6:33 am live hit - completed • Bern ie and Sid Radio Show - NYC - 7:05 am live hit - completed • CNN Cuomo - scheduled live hit 9 :05 p.m. Thur sday 3/26 • WTOP- schedu led live hit 6:10 a.m . • NPR Morning Edition - scheduled live hit 7:07 a.m . • YouTube content creato r interviews - scheduled 11 a.m. • lnstag ram Live video with Steph Curry- schedu led remote conversat ion 1 p.m. • CNN Town Hall - scheduled 8 p. m . live -Podcasts : (b) (5) NIH-000 174 (b) (5) Jennifer Routh [E] News and Science Writing Branch Office of communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7 A 17C Bethesda, MD 20892 Direct: Cb)(6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy end Infe ctious Diseases shall not accept liabi lity for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representative s. From: Routh, Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 8:00 PM To: 'O'Malley, Devin M. EOP/OVP' ------------=-~ (b)( 'Henning, Alexa A. EOP/WHO' 'Bowman, Lauren K. EOP/WHO' ------------ '>; 'Love, Kelly A. EOP/OVP' (b)(6)>; (b)(6)>; ___ _:_ _____ ..:,_ ___..!=::,,;-----------> (b)(6)>; 'Porter, Macaulay V. EOP/OVP' (b)( 6) Cc: Billet, Courtney (NIH/NIAID} [E] >; Stover, Kathy (NIH/NIAID) [E] "':""-."".""."":--:""'""".""."== = )=(6) (b :::...; >,:... ·C _o_n,..... ra,...,. d,;, , Patricia (NIH/NIAID) [E] (HHS/ASPA) (b)(6); Murphy, Ryan (OS/ASPA) Subject: RE: Dr. Fauci hits and requests (b)(6); Hall, Bill (b)(6) (b) (5) Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/H HS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attachmen ts is confidential and may con tain sens itive information. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sender and delete it NIH-000175 from you r mailbox or any other storage devices . The Natio nal Institute of Allergy and Infe ctious Diseases shall not accept liab ility for any statements made that are sende r's own and not expressly made on behalf of the NIAIO by one of its representatives. From: Routh , Jennifer (NIH/NIAID) [E] Date: Tuesday, March 24, 2020 7:48 PM To: O'Malley, Devin M. EOP/OVP ------------=-:~ __ ---~----:----::===-.,;__..,:__.,,,:_ (b)( Cb _ )_ C_6); Henning , Alexa A. EOP/WHO _________ Bowman, Lauren K. EOP/WHO ___ .,:______ >; Love, Kelly A. EOP/OVP ..:__~ = (b)(6) (b)(6)>; Porter, Macaulay __:__~ (b ~)~(6) ::::,;----------> V. EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] >; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Hall, Bill (b=H=6)>; Murphy, Ryan (OS/ASPA) (b)(6) (b)(6)>; Conrad, Patricia (NIH/NIAID) [E) "':": (H -:-:H-:-:: S7. /A:-:: S-::PA :-:)-;:::===:::..;..--,;- Subject: RE: Dr. Fauci hits and requests (b)(5) Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relat ions National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MO 20892 Direct: (b) (6) (b)(6) Disclaimer : The information in this e-mail and any of its attac hments is confidential and may contain se nsitive informat ion. It should not be used by anyone w ho is not the original intended recipient. If you have received this e-ma il in error please inform the sende r and delete it from you r mailbox or any othe r storage devices. The National Institute of Allergy and Infectio us Diseases shall not accept liab ility for any statements made that are sende r's own and not express ly made o n behalf of the NIAID by one of its representatives . -------------- (b)(6) From: O'Malley, Devin M. EOP/OVP Date: Tuesday, March 24, 2020 7:41 PM To: Love, Kelly A. EOP/OVP -------- (b -=-= )""" (6) = >; Routh, Jennife r (NIH/NIA ID) [El (b)(6); Henning, Alexa A. EOP/WHO ow man, Lauren K. EOP/WHO ---------8 ___ .,:______ __:__~ (b ~)~(6) ::::; ----------> (b)(6)>; CbH >; Porter , Macaulay V . EOP/OVP Cc: Billet, Courtney (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [E] (b)(6); Hall, Bill "'.". (H ""."'. H ""."'. S'."": / ""." AS ~P'.""'. A-:) ===::::..,;:,._ =(bS"": H=6)>; Mu rphy, Ryan (OS/ ASPA) CbH > Subject: RE: Dr. Fauci hits and requests (b) (5l NIH-000176 --------------~~ From: Love, Kelly A. EOP/OVP (b) (6)> Se nt : Tuesday, March 24, 2020 7 :34 PM To: Routh, Jennifer (NIH/NIAID) [El (b)( >; Henning, Alexa A. EOP/WHO (b)(6); Bowman, Lauren K. EOP/WHO (b)(6) ; Porter, Macaulay V. EOP/OVP___________ ===========-~:-- -----------~ Cc: Billet, Courtney {NIH/NIAID) [El .~:-:-:--::-:-:-::=== = Cb _)_(6) ... (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)=(= 6)~; c _o""" n..,... r= ad, Patricia (NIH/N IAID) [El CbH6)>; Mu rphy, Ryan (O5/ASPA) (HHS/ASPA) Devin M . EO':" P/-:-0:-:V"'."': P-===== (b)(6); Hall, Bill CbH >; O'Malley, CbT<6l> Subject: RE: Dr. Fauci hits and requests (b) (5) From: Routh, Jennifer (NIH/NIAID) [El ---------- (b)(6) Date: Tuesday, March 24, 2020 7:26 PM ---------=-=-:-= __....:.__..:.,_ _____: __!:=~~------ To: Love, Kelly A. EOP/OVP (b)(6)>; Henning, Alexa (b)( A. EOP/WHO 6)> Cc: Billet, Courtney (NIH/NIAID) [El (b)(6)>; Stover, Kathy (NIH/NIAID) [E] (b)(6)>; Conrad, Patricia (NIH/NIAID) [El ,__"""".""'""""""-0:-::===:::!...,;,-c:-:-:=, (HHS/ASPA) (b)(6)>; Mu rphy, Ryan (OS/ASPA) Subject: Dr . Fauci hits and requests --:-:::======~~ --------- Good eveningBelow is an updated list of t he hits and pending requests for Dr. Fauci. Tuesday 3/24 • 7 am firm live hit Chris Stigall Radio Show (Ph illy) - completed • WMAL in woe - comp leted • 10 pm live with Laura Ingraham truck from his house - scheduled Wednesday 3/25 • Bob Rose Radio Show - Gainsville Fl - 6:33 am live hit - scheduled • Bernie and Sid Radio Show - NYC - 7:05 am live hit - scheduled • WTOP - work ing to schedu le • NPR Morning Edition - wor king to schedule (b) (5) NIH-000 177 (b) (5) Jenn ifer Routh [E] News and Science Wr iting Branch Office of Communications and Govern ment Relations National Institute of Allergy and Infectious Diseases (N IAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) (6) (b)(6) Disclaime r: The information in this e-mail and any of its attach ments is co nfidential and may con tain se nsitive info rmation. It should not be used by anyone who is not the original intended recipient. If you have received this a-ma il in error please inform the sander and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases shall not accept liabi lity for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. NIH-000 178 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 20201 7:17:12 +0000 Eisinger, Robert (NIH/N IAID) [E) FW: Proposta da un med ico ricercato re it aliano per argi nare l'infezio ne da Bob: Can you figure out a way to get thi s tran slated so th at we ca n figure out wh at he wan ts and wh et her w e can he lp him. Thank s, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MO 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail (b) (6) The information in th is e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: sand ragiudic i@libero.it Date: Saturday, March 28, 2020 1:14 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Proposta da un medico ricercatore ital iano per arginare l'infez ione da Coronavirus ------~~ Importance: High Egregio Professo r Fauci, foreign liiigiii gc NIH-000 179 foreignlaiigiiigc NIH-000 180 foreign liiigiiige dott.ssa Sandra Liliana Giudici Oggetto : Proposal from an Ita lian research doctor to stem th e Coron avir us infect ion Dear Professor Fauci. I'm an Italian research doctor, with a qualification in Internal Medicine, who trained at the Polyclinic Hospital of Milan. (b) (4) NIH-000 181 (b) (4) NIH-000 182 (b) (4) I'm very grateful for the precious time and for the attention that You will want to devote to my "app lication hypothesis". Trusting in Your kind reply, I send my best regards. dr. Sandra Liliana Giudici NIH-000 183 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 202017:15:57 +0000 Janet Tobias Conrad, Patric ia (NIH/NIA ID) [E), FW: Update on Film details, Task Force conversation s, etc. ·------------ (b)(6) Janet: Thanks for the note to Patty. We can do some of #4 below . Patty wil l contact you and we can also chat by phone today to update me on details. As you might imagine, thing are very hectic and the most important thing is for me to get my j ob done. And so we will do what we can but may not be able to do everything that you would like. I look forward to speaking with you later. Best regards, Tony Anthony S . Fauci, MO Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MO 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in er ror please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ----------------=-------- = From: Conrad , Patricia (NIH/NIAID) IE] Date: Saturday, March 28, 2020 7:28 AM (b)( '> To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: Update on Film details , Task Force conversa t ions, etc. Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: March 28, 2020 at 7:24:48 AM EDT To: "Conrad, Patricia (NIH/N IAID) [E]" _______ NIH-000184 """ (b) ,..., (=6)> Cc: "Bil let, Courtney (NIH/NIAID ) [E]" --------- (b)(6)>, " Routh, Jennifer (NIH/NIAID) [E)" (b)(6) Subject: Update on Film details, Task Force conversations, etc. Hi Patty: A few impor t ant updates. And a request for this weekend/Sunday. (b)(4) 2) We have been working w ith John Burklow/Dr . Collins/HHS on access to the Task Force. The Task Force came back to us and asked us for more details about our approach, we gave them a writt en description of the overall approach of docum ent ing for history the role of the Task Force, it's leadersh ip, NIH, NIAID, and Dr. Fauci. Burklow is working with us on this . 3) Could I have a ten minute phone conversat ion with Dr. Fauci th is w eekend, importantthink-to update him on details personally. I 4) We wou ld like, if possible to start filming wit h Dr. Fauci this weekend . Could we film Dr. Fauci exiting his house and going to the live truc k for Sunday morn ing inte rviews and then going back home or off to the WH. We would then match that in the film wi t h the feed from the truck of him sit ti ng down and get archive from the shows he appears. We are close by. Zac (DP, who Dr. Fauci knows) has been in complete self-quarantine for two weeks before he left New York State and we are now here a week . He is comp letely good by self-quarantine rules for above filming . Thanks to the th ree of you fo r t he work . The commun ication is life -saving. I have a couple of close friends on the frontline and they asked me to re lay how deeply grateful they are for the work you are all doing. Janet NIH-000 185 On Mar 24, 2020, at 3:38 PM, Conrad, Patricia (NIH/NIAID) [E] Cb)<· wrote : ---------Hi Janet I gave him a hardcopy of your email earlier today ...he does have it- we had to add some meetings at the WH prior to his Task Force meet ing so I know he was a bit distracted .. Wil I keep trying ... Patricia L. Con rad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original inten ded recipient. If you have received this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statemen t made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, Ma rch 23, 2020 9:26 PM To: Conrad, Patricia (NIH/NIAID) [E]_______ -,a(b),..., (=6)> Subject: Here and working Hi Patty: Zac and I are here and situated . I know you are dr inki ng th rough ten firehoses. I want to preserve sleep and health for Dr. Fauci. But it would be fantastic to have a 15 minute video (with distancing) Q and A in the garden of his house or in the house t his week--- what he is working on just scientifica lly -vaccines, t reatments, disease understanding. I want to capture the focus and urgency of the real time scientific work on COVID-19. lfwe need to we can figure out how to do it wi t h audio, but would love to see if we could do this in 15 minutes on video. Again, anytime this week . NIH-000186 Thanks, Janet NIH-000187 From: Date: To: Cc: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Sat, 28 Mar 202017 :00:15 +0000 Auchincloss, Hugh (NIH/N IA ID) [El;Erbe lding , Emily (NIH/NIAID) [El (bH ;Conrad, Patricia (NIH/NIAID) [El FW: NIAID-NIBIB discussion ------- Attachment s: COVI D_ ICD_ Trom berg.pptx Hugh/ Emily: Please handl e th is and respond t o Bruce fo r me. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Tromberg , Bruce (NIH/N I BIB) [El (b)(6) Se nt: Saturday, March 28, 2020 10:55 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)>;Auchi ncloss, Hugh (NIH/N IAID) [El ________ (b) _C_6)>; Erbelding, Emily {NIH/N IAID) [El (b)(6) Cc: Heemskerk , Jill {NIH/NIBIB) [El (b)( >; George , David {NIH/N IBIB) [El ------~= (b)(6)> Subject: NIAID-NIBIB discussion Hi Tony, Hugh , and Emily Hope you are doing well and gett ing a chance to pause (especia lly Tony!) after ano t her breathless sprint of a week . The NIBIB comm unity has unique capacity to design, build , and deploy an array of power ful biomedical technolog ies. Much of our attention over the past year has been on early disease detect ion and preve ntion, and the integration of digital/pe rsonal health with conventional medicine . The COVID-19 crisis seems to have many challenges that are ideally matched for our capabilities . With the $60M NIBIB will receive in the supplement, we are in a unique posit ion to make a contribution. NIH-000 188 I am hoping we can meet with you to refine ideas and coordinate as we develop mechanisms to marshal these resources. Your insight will play an essential role in helping us move forward wisely. NIBIB has never received anything remotely like this before and we are in unfamiliar territory. I think it reflects, in part, the confidence---and hope, that people have in advanced technologies to change lives. We are determined to convert these dollars into tangible methods and devices and need your help in optimizing our strategy. I am forwarding my slide from the science presentation on Wednesday and my follow up email to Francis and Larry to give you a sense of our direction {apologies for the information blast!). We have also been drafting a NOSIwith several topic areas that I am adding below ...note that we are in the process of condensing and refining these to simplify and more closely resemble our pay plan. I had a great conversation with Francis in a follow up call Thursday and he suggested Cb)(5) I look forward to your thoughts/comments and hope we {cc'd NIBIB leadership Jill Heemskerk and David George) can schedule a time to talk. Thank you for considering this, I know you are overflowing with emails and requests! If it's easierto just give me a call, my cell is (b)(6), I can give you the quick "cliff notes" summary. Best, Bruce (b) (5) From: "Tromberg, Bruce (NIH/NI BIB) [E]" _.;._....;.__ ..;...;;....;;....::::=.~~------Bruce (NIH/NIBIB) [E]" CbH6>(> (b)( > on behalf of " Tromberg , ----------- Date: Thursday, March 26, 2020 at 7:22 AM To: "Collins, Francis (NIH/OD) [E]" ______ ------~~ Cb> _C6) _ >, "Tabak, Lawrence (NIH/OD) [E]" NIH-000189 (b)(6) Subject: Summary thoughts Hi Francis and Larry, Thanks for the opportuni ty to present yesterday . (b) (5) (b)( S) NIH-000190 (b) (5) Best, Bruce Bruce J. Tromberg, Ph.D. Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health Building 31, Room 1C14 Bethesda, MD 20892-2281 (b)(6) 301-480-0679 - FAX (b)(6) http://www.nibib.nih.gov NIH-000 191 (b)(5)- PCR NIH-000 192 (bX5) -PCI NIH-000 193 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 16:19:28 +0000 Folkers, Greg (NIH/NIAID) [E) RE:What's new for 'fauci as' in PubMe d thanks Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------- ::;..,..-,= From: Folkers, Greg (NIH/NIAID) [E] Date: Saturday, March 28, 2020 11:16 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: What' s new for 'fauci as' in PubMed (b)(6)> (b)(6J> Will see to that these are on your cv From: NLM/NCBI efback Date: Saturday, March 28, 2020 6:17 AM To: Folkers, Greg (NIH/NIAID) [E]..-------,, (b._..., )(= > Subject: What's new for 'fauci as' in PubMed This message contains My NCBI what's new results from the National Center for Biotechnology Information (NCBDat the U.S. National Library of Medicine (NLM). Do not reply directly to this message. Sender's message: Search: fauci as Sent on Saturday, 2020 March 28 Search: fauci as View comp lete results in PubMed (results may change over time). NIH-000 194 Edit saved search settings, or unsubscribe from these e-mail updates. PubMed Results Items 1 - 2 of 2 1 Covid-19 - Navigating the Uncharted. Fauci AS, Lane HC, Redfie ld RR. N Engl J Med. 2020 Mar 26;382(13) :1268-1269. doi : 10.1056/NE JMe2002387 . Epub 2020 Feb 28. No abstract available. PMID: 32109011 [PubMed - indexed for MEDLINE] Similar articles 2 Role of T-cell trafficking in the pathogenesis of HIV disease. Cicala C, Arthos J, Fauci AS. Curr Opin HIV AIDS. 2019 Mar;14(2):115 -120. doi: 10.1097 /COH.0000000000000529 . Review . PMID: 30601238 [PubMed - indexed for MEDLINE] Similar articles NIH-000195 From: Date: To: Subjec t : Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Sat, 28 Mar 2020 14:18:32 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: Updates, In DC Email below from Janet Tobia s. Robert W. E isinger, Ph.D. Special Assistant for Scientific Projects Immediat e Offi ce of the Directo r National Institu te of Allergy and Infectious Diseases Nationa l Institu tes of Health 31 Cen ter Drive , Room 7A-03 Bet besda MD 20892 Tel ephon e: (b)(6) Emai l: (b)( -----Original Message- ---From: Janet Tobias Date: Saturday, March 28, 2020 7:27 AM To: Fauci, Anthon y (NIH/NlAJD) [E] Subject: Re: Updates, In DC --------==-=--: = --------- (b) (6) Dear Ton y: 1 sent a note to Patty with upda tes. Ta sk Force in progress (asked for more information) and we have finalized plans for dis tribution/release of the film for when this is over next year and we all feel good about being together in a theater. Will now push to do tiny bit s of filming and audio a couple of times a we ek. Thanks for everything and thanks yesterday for talking to the frontline. Close friends there have asked me to pas s on their gratitu de. See you soon and follow Chris ' advice about taki ng care of yourself. Jan et > On Mar 22, 2020 , at I 0: 1.9PM, Fauci , Anthony (Nil-I/NlAID) [E] ______ > > Cb ._ 6l> wrote: H...., My work with the Coronavi rus Task. Force aod tbe large vo lume of incoming email:, preclud es me or my ~taff from answer ing each individua l messag e. l would encourage yo u to visit www .coronavirus.g ov for the latest informati on and guidance related to COVID - 19. > > Thank you, and best rega rds . > > Anthony S. Fauci, M.D. > > > NIH-000 196 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 28 Mar 2020 12:29:3 1 +0000 Burklow, John (NIH/OD) [E) RE:Great videos! To: Subjec t : Thanks,John! From: Burklow, John (NIH/OD) [E) -------Se nt : Friday, March 27, 2020 6:32 PM (b)(6) -----~~ To: Myles, Renate (NIH/OD) (El (b)( >; Fine, Amanda (NIH/OD) (El (b)(6); Akinso, Woleola (NIH/OD) [E] (b)( •>;Olander, Alyson "'."'."'."'."."'."'":'::-::"''.""":":":";:===~-__; ~= (NIH/OD) (El (b)(6) >; Cox, Todd (NIH/CIT) [E] CbH ; Rosado, Andrew (NIH/CIT) [E) (b)(6) Collins, Scott (NIH/CIT) [E (b)(6) Chen, Josep hin e (NIH/CIT) [E) (b)( ; Welch, Will (NIH/CIT) [E) ~ CbH ~ >; Diane Baker Cb)(6) Cb)( >; Rice, David (NIH/OD) [E] ; Awwad, David (NIH/NIAID) [CJ =======~ ~ -------- Cc: Collins, Francis (NIH/OD) [E] _______ ; Fauci, Anthony (NIH/NIAID) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (b)(6); Norris, Andrea (NIH/CIT) [E] (b)(6) ; Alboum, Stacie (NIH/CIT) [E] (b)(6)>; Johnson, ---:---'.======:f..-~~ Alfre d (NIH/OD) [E] (b)( Prince, Scott (NIH/OD ) [E] (b)(6)] Chew, Debra (NIH/OD) [E] (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)(6) Billet, Courtney (NIH/NIAID) [E) (b)(6)]; Conrad, Patricia (NIH/N IAID) [E] (b)(6) Subject: Great videos! Congratulations to all of you who made today's COVID-19 videos a tremendous success! I know t here were a lot of quickly moving, intricate parts and it went off flaw lessly - all remotely, to boot! Everyone worked as a team, under very ti ght timelines, and thanks to Renate, who orchestrated the FCHome Edition! I know NIH staff will greatly appreciate the videos-they're chockful of content! And special th anks to Dr. Fauci, who took time out of his "leisurely" day to devote more than an hour to the taping - incredible! You all make us very proud! John NIH-000 197 From: Date: To: Subject: (b)(6) Fri, 27 Mar 2020 17:51 :23 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Reaching out from Frame/Urgent Begin forwardedmessage: From: Ben Moe Date: March 27, 2020 at 5:47:50 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: Reaching out from Frame/Urgent ------~~ -------- (b)(6Ji Dear Dr. Fauci, I hope all goes well. I wanted to quickly follow up and see if you might be free for a quick interview on Monday - it would mean so much to include your voice in the piece. Is there a time on Monday that might work for you? We can jump on the phone for a 5 - 1O minute call if that works better for you. Best, Ben On Thu, Mar 26, 2020 at 5: 10 PM Ben Moe wrote: Dear Dr. Fauci, I hope this finds you well and thank you for all the work you are doing. I run the digital magazine, Frame, which publishes interactive documentaries made for mobile phones. We are working on a story about the current effort to create a coronavirus vaccine and would love to interview you for the piece. We've interviewed Regeneron's Chief Scientific Officer, George Yancopoulos , and the piece will tell the story of Regeneron's push to create a coronavirus vaccine in record time. I was hoping you could speak to the broader issue of the often undercovered global threat of diseases and the lack of funding going toward infectious diseases . NIH-000198 Would you potentially be available for a short video interview sometime between 10am - 7pm EST tomorrow? Alternatively, would you be free sometime between 12pm - 2pm or 5pm - 7pm EST on Monday? Look forward to hearing back and we'd be honored to have your voice in the story. Here's a brief overview of Frame: Frame is a newsmagazine that publishes interactive documentaries made for mobile phones. Every Frame story tells a compel ling, human story that helps shine a light on a major social or political issue. Frame stories include interactive features throughout, from maps to timelines, that allow viewers to engage more deeply with the piece . Our stories are delivered through a messaging platform that allows subscribers to have conversations with our journalists and subscribe to news updates on topics they want to follow, all through SMS. Frame has been covered by TechCrunch, Poynter, and Journalism.co.uk, and our investors include Snap lnc.'s Yellow Accelerator. The very best, Ben Moe Founder and CEO , Frame ben @frame.media @beneliasm oe Founder and CEO, Frame ben @frame.media @beneliasmoe NIH-000199 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 17:48 :31 +0000 Hirsch, Vanessa (NIH/NIAID) [E] RE:appreciat ion Thanks, Vanessa. I appreciate yo ur note . Best , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------::-::-:-= -------- From: Hirsch, Vanessa (N IH/NIAID) [El Date: Friday, March 27, 2020 10:28 AM To: Fauci, Anthony (NIH/NIAI D) [El Subject: appreciat ion (b)( 6) (b)( 6)> Hi Tony , I ju st wa nted to express my appreciat ion for your sane voi ce duri ng the Covid-19 cris is. Keep up the good work . I know it has to be exhaust ing. Best regards, Vanessa Hirsch NHPVS, NIAID, NIH NIH-000200 Fauci, Anthony (NIH/NIAID) [El Fri, 27 Mar 2020 15:57:33 +0000 Morens, David (NIH/NIAID) [E) Folkers, Greg (NIH/NIA ID) [E] From: Date: To: Cc: Subject: RE: (b)(4) David: Provided you that would be great . Thanks, --------- (b)(6), if you could do this wit hin t he next 2 to 3 weeks, Tony Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly behalf of the NIAID by one of its representatives. (b) (6) > From: Morens, David (NIH/NIAID) [E] ---------27, 2020 11:27 AM Se nt : Friday, March To: Fauci, Anthony (NIH/ NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [El Subject: Cb)(4) -------~~ made on ..:..==-=====-~~ ---------- Tony, start to think about what might work . ----------------------------- (b)(6) (b)(6) (b)(4), so I wil l Do you have a hoped-for t imetable? We are both overwhelmed, but I will try to do at least a bit daily as long as (b)(6) . david NIH-00020 1 From: Morens, David (NIH/N IAID) [E] Se nt: Friday, March 27, 2020 11:24 AM To: Narasimhan, Sri Devi (ELS-CMA) Cc: Fauci, Anthony (NIH/N IAID) [E] Subject: RE: Subj ect: CbH4) Dear Sri, thank you and we wish you and colleagues well too. These are certainly d ifficult times for all. (b) (4) We'll ponder that some more and get back to you later. Thanks, again, and stay saf e David M. Morens, M.D. CA PT, Uni t ed States Publi c H ealt h Service Senior Advi sor t o th e Director Office of th e Director National Institut e of Allergy and Infectious Diseases Nationa l Institut es of Health Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 Bethes da, MD 20892-2520 CbH assistants: Kimberly Barasch; Whitney Robin son) Q Disclaimer: This message is intende d for the exclusive use of the recipient(s) named above. It maycontain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated , disttibuted , or copied to persons not authorized to receive such information . All sensitive documents must be propuly labeled before dissem.in1ctionvia email. If you are not the intended recipient, any dissemination, distribution, or copyin,g is strictly prohibited. If you h ave received this communication in error , please erase all copies of the message and its attachments and notify us immediately. NIH-000202 From: Narasimhan, Sri Devi (ELS-CMA)<> Date: Thursday, March 26, 2020 9:23 PM To: Morens, David (NIH/NIAID) [E] Cc: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Subject: --------~~ ___ ...:....:,....:..:;=======--~.-:=-(b)(6) --------------- (b)(4) Dear Tony and David, Thank ou for writin back. First! I would like to sa thank ou for all that ou are doin . On (b)(4) I hope you, your families and colleagues stay safe and healthy through this. Please take care. I look forward to staying in touch. Best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier SOHampshire St., Cambridge, MA 02139 srnarasimhan@cell.com (b)(6)> From: Morens, David (NIH/NIAID) [E] --------Date: Thursday, March 26, 2020 4:53 PM To: Narasimhan, Sri Devi (ELS-CMA) Subject: Subject: (b)(4) Dear Sri, we're responding, at long last, to your inv itation to Tony Fauci severa l weeks back, to (b) (4) NIH-000203 First, apologies are in order. We tried to meet about this and get you a quick response the day after you and Tony emailed, but then coronavirus chaos ensued. We had to cancel 5 successive meetings to go over this; in one case minutes before we were to start he got an urgent call to go down to the White Hose asap, and that was that. Few of us in the office have even seen Tony in recent weeks as he is down at the White Hose daily from early morning until late at night. Finally this morning we sat down and had a relaxed discussion. Assuming you are still 4L_.,,_, (b) ( (b) (4) ________________ ..... (b)( 4). Crazy times, for sure. Thank you, I look forward to hearing from you, << OLE Object: Picture (Device Independent Bitmap)>> David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Ins ti tute of Allergy and In fectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda, MD 20892-2520 ir (b)(6)stants:Kimberly Barasch; Whitney Robinson) ~ ~ Disclaimer:This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED, and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copied to persons not authorized to receive such information. All sensitivedocumentsmust be properly labeled beforedisseminationvia email.If you are not the intended recipient, any dissemination,distribution, or copyingis strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-000204 << OLE Object: Picture (Device Inde pendent Bitmap)>> From: Narasimhan, Sri Devi (ELS-CMA) Date: Monday, January 27, 2020 4:00 PM To: Fauci, Anthony (NIH/NIAID) [E] < Subject: ------~= CbH> Cb)(4) Dear Tony , I hope all is wel l. I had the great pleasure of meeting you in person when you were the keynote speaker at our Cell Symposium on Emerging and Re-emerging Viruses in 2017. You t hen gave a wonderful talk that covered AIDS to Zika and your expe riences across different outbreaks, administrations and the challenges you encountered. (b) (4) My best wishes, Sri. Sri Devi Narasimhan, PhD Deputy Editor, Cell Cell Press/Reed Elsevier 50 Hampshire St., Cambridge, MA 02139 srnarasimhan@cell.com NIH-000205 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [El Fri, 27 Mar 2020 15:56 :36 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Offering help to fight th e Civod-19 Presentation Doc-line.pdf Please check it out and respond Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7 A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Peter Lermen (b) (6) Date: Friday, March 27, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Offer ing help to fight the Civod-19 ------~~ -------- (b)(6)> Dear Dr. Fauci, I don 't wan t you to waste too much time in th is stressful situation. As t he doctor in charge of the hygiene of t he Berner clinic in Crans-M ontana in Swit zerland, as w ell as being in contact with my colleagues in private practice , I see every day how important the need for information and consultation of t he popu lation in this situation of insecurity is. At the same time , we are under threat of a shor tage of doctors if we have to strictly apply the federal swiss guidelines (Art. 10b and 10c, regulation 2 COVID-19) or if the wave of illness reduces the number of colleague s available for consulta tio ns. (b) (4) NIH-000206 Thank you for your time Good luck Best regards, [) () C-} i 11C Peter Lermen MD internal medicine, interna l oncological rehabil itation Co-President oncoreha.ch (b)(6) www .doc-lin e.ch NIH-000207 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/N IA ID) [E) Fri, 27 Mar 2020 13:30 :18 +0000 Mascola, John (NIHNRC) [E) FW: Vir update Vir Barda TechWatch _05 Ma r20_vF.pptx Please take a look at this and respond if appropriate.. to tackle . I have 745 others . Thanks, Tony Too long an e-mail for me Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Skip Vi rgin (b)(6)> Date: Tuesday , March 10, 2020 11:33 PM To: Fauci, Anthony (NIH/NIAID) [E]-----Subject: Vir update (b =)""' (6) => Tony My apologies for the slow update . You asked that I get back to you after Cb> C4>and so here I am. Notes in sections. (b)(4) NIH-000208 (b) (4) NIH-000209 (b) (4) Any advice welcome Happy to talk ____ Cb _H_6) Be well and thanks for all of your public work to help us prepare . I wish they listened more . Skip Herbert W. 'Skip' Virgin M.D., Ph.D. Executive Vice President, Research Chief Scientific Officer Vir Biotechnology 499 Illinois Avenue San Francisco CA 94158 he/him/his NIH-000210 From: Date: To: Cc: Fauci, Anthony (NIH/NIAID) [E] Thu, 26 Mar 2020 16:19:31 +0000 Giroir, Brett (HHS/OASH) Kadlec, Robert (OS/ASPR/IO);Birx, Deborah L (b)(6);Lerner,Andrea (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [E];Redd, Stephen (CDC/DDPHSIS/0D) Subject: FW: Draft of email for ASFto send to Brett Giroir cc'ing Kadlec Attachmen ts: IMG_2072.mov -------------Brett: The proposal below was sent to my office by David Margu lies (Harvard/Boston Childrens) who is part of a group of prominent physicians and healthcare executives in Boston developing this idea (David Martin of the Brigham, Gary Gottlieb of Partners and others). See this op-ed th ey wrote in the Boston Globe yesterday regarding their proposal https://www.bostonglobe.com/2020/03/25/opinion/mass-needscomprehensive-care-response-coronavirus /l . (b)(5) Can you take a look at this and let me know what you think? (b)(5J. David -..:=.=======:::::;;::;;;;-:~ Margulies can be contacted direc tly at (b)(6) or (bJ(6) if you need additional information. Thanks, Tony (b)(4). (b)(5) NIH-000217 (b) (4), (b) (5) David Margulies, M.D. (b)(6) NIH-0002 18 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 26 Mar 2020 13:25:30 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:FORTASKFORCEConsiderat ion -- Some sound th inking on COVID-19 To: Subject: We have been discussing each and every one of the se suggestion s and th ey are all on th e t abl e fo r considerat ion of imp lementati on. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r's own and not expressly made on behalf of the NIAID by one of its representatives. From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Thursday, March 26, 2020 9:08 AM To: Fauci, Anthony (NIH/ NIAID) [E]------= (b) ""'~= > Subject: FW: FOR TASKFORCEConsideration -- Some sound thinking on COVID-19 Importance:High Patricia L. Conrad Publi c Health Ana lyst and Special Assist ant to the Directo r National Instit ute of All ergy and Inf ectious Diseases The Nati ona l Inst itutes of Healt h 31 Center Drive , MSC 252 0 - Roo m 7A03 Bet hesda, M aryland 20892 (b)(6) 301-496 -440 9 fax Discla imer: The informat ion in this e- mail and any of its attachm ents is confide ntial a nd may conta in sensi tive information . It shou ld not be used by anyon e who is not the original intended recipient. If you have rece ive d this e-m ail in error please inform the sende r and delete it NIH-0002 19 from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender's own a nd not expressly made on behalf of the NIAID by one of its representatives. From: Conrad , Patricia (NIH/NIAID) [E] (b)(6J> Date: Wednesday, March 25, 2020 6:3 1 PM To: Conrad, Patricia (NIH/NIAID) [E] (bH > Subject: FW: FOR TASK FORCEConsiderat io n --Some sound think ing on COVID-19 Importance: High --------, ~= From: Pierce, William Date: Wednesday, March 25, 2020 4:24 PM To: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Subje ct: FOR TASK FORCEConsideration -- Some sou nd th ink ing on COVID-19 ----------=-::-:-= Importance: High Patty: I know Tony is the expert, but I thought this memo would be of interest and perhaps of help to him in his battles . The attached memo is from Dr. Paul Offit (U of Penn) and a colleague of his David Rubin. Tony may know him, I would not be surprised. But for you, Paul is one of the country's topic vaccinologists and virologists. Paul developed a vaccine for a deadly disease. I know him well and he's the real deal. Next t o Tony he is my go to science source. Paul in particular is a highly credible , well known nat ional expert. They wrote this memo on the 19th of Ma rch and it has many suggestions that are incredibly smart and I thought tony would want to see th is immediately. Paul and David are obviously available to talk asap . Let me know. Bill William Pierc e Senior Director APCO Worldwide 1299 Pennsylvania Ave, N.W. Suite 300 Washington, DC 20004 (t) +1 202 659 7931 (m) ___ _,(l> _.,. ).,..,, NIH-000 220 wpierce@apcoworldwide.com @apcowortdwide :::::: Learn more about APCO resources available during the COVID-19 outbreak::::.: CONFIDENTIALITY This email may contain material that is confidential, privileged and/or work product for the sole use of the intended recipient Any review, reliance or distribution by others or forwarding without express permission Is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies William Pierce APCO Worl Date: Thursday, Ma rch 26, 2020 5:02 AM To: Fauci, Anthony {NIH/NIAID) [E]______ """ (b"""' )(=6) Subject: BBC News Hello Dr Fauci I'm the programme editor of The Nine, a nightly news and current affairs programme on the BBC. I was hoping you could spare ten minutes at some point today (March 26) to speak to us over Skype or FaceTime about the US response the Coronavirus pandemic. If that's possible, I'll ask one of my producers to arrange it at a time convenient for you . Chris Foote Senior Journalist BBC News (b)(6) http://www.bbc.co.uk This e-mail (and any attachments) is confidential and may contain personal views which are not the views of the BBC unless specifically stated . If you have received it in error, plea5e delete it from your system. Do not use, copy or disclose the information in any way nor act in reliance on it and notify the sender immediately. Please note that the BBC monitors e-mails sent or received. Further conununication will signify your consent to this. NIH-000223 (bX5)-PCE NIH-000224 NIH-000225 From: Date: To: Subjec t : Fauci, Anthony (NIH/NIAID) [El Thu, 26 Mar 2020 02:27:28 +0000 Joubert, Bonnie (NIH/NIEHS) [El RE:Thank you Bonnie: Thanks for the note. Much appreciated. Best regards, Tony --------- From: Joubert, Bonnie (NIH/NIEHS) [El Date: Wednesday, March 25, 2020 9:50 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you (b)(6) CbH6J> -------- Dear Dr. Fauci, I just want to say THANK YOU for all that you are doing for the country to address the COVID- 19 pandemic. As an epidemiologist at NIEHS,it is inspiring and encourag ing to be part of NIH and to have leaders like you involved in the national and global response during this critical time. Regards, Bonnie Bonnie Joubert, MPH, PhD Population Health Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, NC 27709 Phone: (b)(6) NIH-000226 Fauci, Anthony (NIH/N IAID) [E) Wed, 25 Mar 2020 17:20 :55 +0000 Friedmann, Theodore RE:George Church interview From: Date: To: Subject: Thanks, Ted. I appreciate your note. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Friedmann, Theodore Date: Tuesday, March 24, 2020 4:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Fwd: George Church interview ------- ---,= Dear Tony : I sent a brief note to my friend Jon Cohen to congratulate him on what I thought was h is fine interview with you. In his response, he suggested that I should send a copy to you. I've been a little reluctant to do that because of what I assumed must be a flood of comments and advice that you are getting in your role on the task force. I attach the message to Jon below and I hope that some of the thoughts are useful and maybe a little comforting for you. With my very warmest regards and best wishes, Ted Begin forward ed message: From: The odo re Friedman n NIH-000227 .ucsd .edu> Dear Jon: Greetings from La Jolla. Congratulations on your interview w ith Tony Fauci. I have to admit that, until a couple of weeks ago, I have been quite critical of Tony's apparent acquiescence with so much dangerous, incorrect and politically motivated misinformation from the administration. I feared that the upside-down explanations from the administration had the effect of destroying the concepts and tenets of epidemiology and even rat ionalizing a completely wrong concept of communicable disease that holds that it is unnecessary to screen for carriers in an ep idem ic but only important to screen symptomatic people. That is upside-down from what we all know about dealing with epidemics and has even been endorsed by Trump, Pence and other members of the COVID-19 task force. It seems to have become a new normal concept of communicable disease management. Like so many things in the Trump era, facts and history are thrown out the window and replaced by governmentally espoused but obviously wrong concepts. We assume to be preparing to complete ly deny established concepts of communicable disease - screen only the prime suspects or the afflicted. In conversations with colleagues here I wondered "where is Tony Fauci?" They suggested that he must be quietly and heroically working hard being the scenes and at his personal peril to educate our leaders rather than correcting th em publicly. But I thought that, in desperate times, the public must hear and see clear truth and denials of lies. My concept of heroes are people who act at their personal peril - Rosa Parks, Martin Luther King, Martin Niemoller, Dietrich Bornhoffer, Thankfully, I th ink that the real Tony Fauci has emerged, obviously to his peril. I wish him good luck and survival. I find myself wondering what the responses will be t o Trump 's likely premature lifting of isolation and quarantining procedures and if the concept of disobeying illegal and unethical orders will survive the times. Ted On Dec 6, 2018, at 11:17 AM, Jon Cohen wrote: So good to hear from you and do te ll Carl to contact me. Yes, George has received ample criticism, but my job is to air his views, regardless of what I think. And I like his independent, damn the torpedoes approach. He speaks his mind. As for He, everything about th is is bizarre, from ethics to science to PRto regulation . Best, Jon NIH-000228 On Dec 6, 2018, at 1:19 PM, Friedmann, Theodore wro te: Hello Jon - Greetings fro rrC: (b>c<1 . It has been a long time since we last connected and talked about gene therapy, etc. and (b)(6) I was very interested to read George Church's troublesome responses in your interview with him in Science and to see his ethical evaluation of He's CCRS editing experiment in China. I'm not as generous to He as George seems to be and I think that th is work is clearly unethical. George inexplicably conjures up the sad history of JessGelsinger and the effect of his death on the evolut ion of the field of gene therapy. Happily, he's right about the fact that gene therapy is now proving itself in a growing list of intractable diseases (underscored by the 2015 Japan Prize). That has happened because stud ies are now much more carefully designed and carried out. But sadly, we are in an environment in which some people conclude that human medical man ipulations - gene therapy, genome editing, stem cell therapy- are ethical as long as they "work". The rationa le is, "let's do the study and if it works and doesn't kill or ot herwise harm, it's OK". It's not a post- factor evaluation that determines if an instance of human experimen tation is ethica l and permissible - it is the design of a study that determines if it is ethical or not. George should be reminded of that fact and should re-read the Helsinki declarations or similar codes of human experimentation. In any event, your interview was fascinating. Best regards, Ted Friedmann NIH-00022 9 From: Date: To: Subjec t : Attachment s: Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 16:59:20 +0000 (b)(6) FW: Developing Control Charts for Covid 3 24 20 with graphs.docx Developing Control Charts for Covid 3 24 20 with graphs.docx Please take a look at this. What do you think ? Anthony S. Fauci, MD Director National Institute of Allergy and Tnfectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2 520 National Institutes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachm ents is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in en-or please inform the sender and delete it from your mai lbox or any other storage devices. The Nat ional Institute of AHergy and Infectious Diseases (NlAlD) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of is representatives. -----Original Message----From: Steve Sternberg (b) (6) Date: Wednesda y , March 25, 202 0 8:39 Al\'[ To: Fauci, Anthony (NlH /NlAlD) [E] (b) (6} Subject: Developing Control Charts for Covid 3 24 20 with graph s.docx ---------=-:-:-= --------=-=-= Tony , Here are reconfigu red charts which factor in the gui dance from mathematicians at Rockefeller. As you can see , the trend in the U .S. is visibly worse. If this pattern holds, we're going to see many more deaths before things get better . We would be grateful for a comment. Could you offer a perspective? We're going to try to publish today. Steve NIH-000230 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/N IAID) [El Wed, 25 M ar 2020 15:01 :21 +0000 DELFRAISSY Jean-fr ancois (b)(6) RE:France situation COVID-19 Jean-Francois: Thank you for your note . I do not see Yazdan copied on your e-mail, andl so please forward this e-mail to him. The NIH position is that we should preferably make drugs available on randomized , controlled clinical trials and not freely distribute them. There is a strong push in the USA, favored by the President, to make certain of these drugs more widely available outside of an RCTusing mechanisms such as "compassionate usage". In the USA, as you know, HC (plaquenil) is an approved drug for malaria as well as for certain autoimmune diseases such as SLE. Thus, physicians can prescribe the drug on an "off label" usage. This likely will be the majo r modality of distribut ion of this drug in the USA, at least for the foreseeable future. I am copying Cliff Lane on this e-mail. Please includ e him on any further correspondence on this subject. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: DELFRAISSYJean-franco is Date: Wed nesday, March 25, 2020 10:35 AM -------------- (b)(6)> -----~~ To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Cc: DELFRAISSYJean-francois ,...:....:;....;;,,!;;=======-----=Subject: France situation COVID-19 NIH-00023 1 (b""" )(=6) > Hello, I am once again in service since the global sanitary crisis COVID-19 hit France a couple of weeks ago. I am now leading the Scientific Council for COVID-19, composed of 10 persons, serving the French President , Emmanuel Macron. The Council was created on March the 10th and we were heavily involved in advisory activities in relation to the President's decision to put the generalized quarantine into force, because we didn't have any better choice. Firstly We have a limited number of diagnosis tests, this prevents us from taking up a Korean-like strategy within the next few days. However, by the end of the quarantine (within the following six weeks), we will be able to have a generalisation of the diagnosis test and develop korean-like apps, as well as a strategy for testing and treatment if we have any drugs available by th is time. Before this, we will go through a difficult phase in the following weeks, because we won't have enough beds in our care units in some part of France ... Secondly On the therapeutic level, Yazdan Yazdanpanah has taken my place and who is now leading REACTing. Tomorrow morning a french -european medical trial will begin, under the control of the WHO, with 5 arms (placebo/kalatra/kalatra +interferon beta / product of Guilead / hydroxychloroquine alone or in combination for next week). As you may know, we are currently facing a press buzz since the announcement made by Dr. Raoult about the effectiveness of hydroxy-chloroquine. His data is not particularly convincing. We can dist inguish a slight positive signal but it must be confirmed by a well made randomised tr ial. We also started a monkey-model study with HC and we should have the results by the end of next week. Also a cohort of severe COVID+ patients have been created and some will be treated with HC : we will analyse those results with all the consciousness needed. It will also be possible to do a prevention trial for healthcare NIH-000232 professionals and aging peoplewith HC.I have an enormous political pressureto releaseHC and to give it to everyonebut I am currently resisting... How is the situation in the USA,especiallyafter Trump's announcement? What is the NIH position ? What will be put into force ? Thanksfor your answer. I put YazdanYazdanpanahin a copy of this email. Best regard Pr. Jean-Fran~ois Delfraissy President IPresident Comite consultatifnational d'ethique pour !es sciences de la vie et de la sante National Ethical Consultative Commiteefoe life sciences and health Ancien Directeur de l' ANRS I ANRS former Director M T _"":::::::::::: NIH-000233 From: Date: To: Cc: Subject: PANTHEON Fauci, Anthony (NIH/NIAID) [E) Wed, 25 Mar 2020 13:57 :28 +0000 Folkers, Greg (NIH/NIAID) [E) Conrad, Patricia (NIH/NIAID) [El RE: ------------------------ (b) (4) Agree. Skip this and please try to get David back on my morning schedule to start working on the original paper that we had agreed upon . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIAID) IE] Date: Wednesday, March 25, 2020 9:29 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/N IAID) [E] Subject: -------- (b) (6)> Cb)( > .'.":.========-=-=--:-= Cb)(6) ---------------------------- (b) (4) (b) (5) NIH-000234 To: Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 12:08 :27 +0000 (b)(6) Subjec t : RE:wi th love fro m Italy From: Date: Rit a: M any th anks f or you r kind not e. It is much app reciat ed . Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-O3 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: rita .apgar@alice .it (b)(6) Se nt : Wed nesday, March 25, 2020 7:58 AM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: with love from Italy (b) ""' (6) => Dear Doctor Fauci. My name is Rita Apgar and if by chance you not iced my last name, as my father said many years ago,' (b)(6)!" I have lived in It aly for almost SOyears and the sagacious finger of desti ny pointed my way to It aly, the true home of my heart , although not a drop of Italian blood flows t hrough it . But the love of Italy and the Ita lians pumps throug h my heart every second of my existence . That sagacious finger of destiny pointed the way, and I followed it in faith to (b)(6) where I had lived . As soon as I set foot for t he fi rst t ime in the house in this funky ghost town of a medieval village, I felt t hat we belonged together. And, practically speaking, at the t ime, it was the perfect solution to some weighty personal problems . Heart and m ind were in peaceful agreement. I have a dear frie nd who is an infectious disease specialist at the hospital in Asti. She is, obv iously, extreme ly busy these days but she took the ti me to call me Sunday evening and we talked about you . She said to me, "you know, when I was j ust a graduate student, I was a secret group ie of Dr. Fauci, and once wh en he was at a me eting or a conferenc e or someth ing (I'm not sur e whe re or wh en) I was able to ask him a few questions ." I was thri lled, of course, since I also try to watch every appearance you make on TV. I will not add anyth ing in this regard. NIH-000235 But I did say to Mar ia, Doctor Maria Degioanni, "Maria, I want to invite Dr. Fauci to come and visit us for a few days when this crisis is over, God willing and maybe he would come together with (b)(6) . who has promised to come and visit again after 20 years. We can put them up in the fancy Relais San Damian above lsolalunga where I live and take them out to dinner at Gente di Mare . Dear Doctor Fauci, I like to joke when peop le ask how we are doing in this time of Covid-19 by saying : A Name, a guarantee : ISOLAlunga= ISOLAtionI Legend says that the Benedictine monks who got into mischief centuries ago were sent here as punishment to work in the olive groves: long isolatio n. Today it's the perfect place to be with a view of the Mediterranean as well as the Maritime Alps from t he kitchen window and hardly a soul to practice social distancing with! Grazie per esistere as an Italian song goes, "thank you for being you! I would adore getting a reply from you, but realize how miraculous tha t woudl be! We would be over the moon if you accepted our invitation , at any time and at the drop of a hat! Sincerely, Rita Apgar NIH-000236 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 10:27 :40 +0000 Jon LaPook FW: Serology for the novel coronavirus Try Barney Graham at the NlAID YRC. You have interviewed him more than once . -----Or iginal Message ----From: Jon LaPook ______ __,(b'"" )..,. (6) = Date: Tuesday, March 24 , 2020 2 :17 PM To: Fauci , Anthony (NTH/NJAlD) [E]..._ ______ Subj ec t: RE: Serology for the nove l coronaviru s --------~~ (b _ )_(.... Sigh. Who wou ld you suggest I try to interview? Thank s, Jon -----01i ginal Message- --- From: Fauc i, Ant hony (NIH/NIAlD) [E]..._ _____ Sen t: Tue sday, March 24, 2020 I :57 PM To: Jo n LaPook (b) (6)> Subjec t: Re: Serology for the novel coronavirus (b _ )_(.... Lots of talk. Not sure about progress > On Mar 23 , 2020 , at 6:27 PM, Jon LaPook > -------- (b) (6)> wrote: > Tony , > Any progress ? Obviously, if we had widespread serologic testing , we co uld identify people with likely immunity , and put them on the front lines. > Thanks , > Jon > > Jonatha n LaPook , M .D. > Ch ief Medical Correspondent , CBS News > Professor of Med icin e > NYU Langone Healtb > Twitter @ DrLaPook NIH-000237 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [E) Wed, 25 M ar 2020 02:26:42 +0000 (b)(6) FW: Serology for the novel coronavirus Cliff: Who is the most knowledgeable about serologies for COVID-19? Thanks , Tony If you know , could you please respond to Jon. -----Original Message----From: Jon LaPook ,;-.-----= (b "')-= (= > Date: Tuesday. March 24. 2020 2: 17 PM...-------~ To: Fauci, Anthony (NTH/NIAID)[E] Subject: RE: Serology for the novel coronavirus (b)( Sigh. Who would you suggest I try to interview? Thanks, Jon -----Original Message----From: Fauci , Anthony (NIH/N1A ID ) [E] Date: Tuesday, March 24, 2020 1:57 PM -------- (b)(6)> To: Jon LaPook (b)(6) Subject: Re: Serology for the novel corona virus Lots of talk. Not sure about progress ------- (6)> wrote: > On Mar 23, 2020, at 6:27 PM, Jon LaPook > (b) > Tony, > Any progress? Obviously, ifwe had widespreadserologic testing, we could identify people with likely immunity, and put them on the front lines. > Thanks, > Jon > > Jonathan LaPook, M.D. > Chief Medical Correspondent, CBS N ews > Professor of Medicine > NYU L ango n e Health > Twi tter @DrLaPook NIH-000238 From: Date: To: Subjec t : From: Daniel Ries Fauci, Anthony (NIH/NIAID) [El Wed, 25 Mar 2020 01:53:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: COVID-19 West Virginia Phenomenon (b)(6)> Se nt : Tuesday, March 24 , 2020 8 :59 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ::;..,..-,= (b)(6)> Subject: COVID-19 West Virginia Phenomenon Dear Dr Anthony Fauci (b) (4) Best regards Daniel Ries PhD Food Technology Massey University NEW ZEALAND (b) (4) NIH-000239 (b) (4) NIH-000240 From: Date: To: Subject: Eisinger, Robert (NIH/NIAID) [El on behalf of Fauci, Anthony (NIH/NIAID) [El Tue, 24 Mar 2020 17:48:57 +0000 Fauci, Anthony (NIH/NIAID) [E) FW: COVID reagent allocation issue Email response from Jeremy Berg Robert W. Eisinger, Ph.D. Special Assistant for Scientific Projects Imm ediate Office of the Director National Institute of Alle rgy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A-03 Bethesda MD 20892 Telephone: (b)(6) Email: (b)( From: Berg, Jeremy (b)(6) Date: Tuesday, March 24, 2020 1:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Lerner, Andrea (NIH/NIAID) [E] Subject: Re: COVID reagent allocation issue (b)(6):> ========= ~ -------- (b)(6) You are welcome, Tony. We appreciate anything that you can do with regard to the reagent allocation issue. The view from the trenches is pretty stark. Keep up t he good work and do not hesitate to reach out to me if I can be helpful in any way. Best, Jeremy Jeremy M. Berg, Ph.D. Universityof Pittsburgh Associate Senior Vice Chance llor for Science Strategy and Planning in the Healt h Sciences Profe ssor of Computational and Systems Biology Scaife Hall , S304 3550 Terrace S1reet Pittsburoh PA 15213 (b)(6) (cell) NIH-000241 From: Anthony Fauci (b)(6)> Date: Tuesday, March 24, 2020 at 1:44 PM To: JeremyBerg CbH6J> -------- Cc: " Lerner, Andrea (NIH/NIAID) [E]" Subject: Re: COVID reagent allocation issue (b)( > Thanks,Jeremy On Mar 23, 2020 , at 9:00 PM, Berg, Jeremy ------ CbH6J> wrote: Dear Tony: I am sure you are overwhelmed, but I think it is important to share the attached with you (which will be sent to you directly through regular channels) . CbH6)is a pathologist who is in charge of testing in a large med ical system in Rochester, New York, who has been extremely concerned and frustrated by the lack of access to reagents for the Roche coronavirus testing platform. They have the platform but cannot use it because of a lack of reagents (which were apparently pre-purchased by Quest, LabCorp, and other national groups). The turnaround time for Quest is approximately 5 days and this is completely useless for making clinical decisions about admission compared with local testing with 24 hour per around time. Thank you for your attention and for everything that you are doing to help our country through this great challenge. Best, Jeremy P.S. I enjoyed the interview with you in Scienceand admire your clarity of purpose. Jeremy M. Berg, Ph.D. University of Pittsburgh Assoc iate Senfor Vice Cha ncellor for Science Strategy and Planning in the Healt h Sciences Profess or of Com put ationa l and Sys tem s Biology Scaife Hall, S304 3550 Terrace Street Pittsburgh, PA 15213 (b)(6) NIH-000242 Cb)(6) ( cell) (b)(6) NIH-000243 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IA ID) [El Tue, 24 Mar 2020 16:27:17 +0000 Lerner, Andrea (NIH/N IAID) [El FW: You m ay be able to help .... Linda is a f orm er NIH Insti t ut e Direct or. Please figure out w hat she is ta lkin g about and respo nd t o her on my behalf Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from you r mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. ---------- From: Birnba um, Linda (NIH/N IEHS)[VJ Date: Tuesday, Mar ch 24, 2020 12:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------= Subject: You may be able to help .... (b)(6)> (b) '"'"' ~= > Hi Tony , Thank you for yo ur tireless efforts to clearly communicate about the pandem ic, including correcting the President when necessary. You do it in such a non -threatening and respectfu l style. I think everyone appreciate s it . (b)(6) runs a home health care company in NC and many ot her states in t he nation . --------He has managed to get some of the largest home care companies as well as the Home Care Associatio n of America (their trade organization) to sign off on this call for guidance for their industry which provides professional care givers, largely CNAs,to those needing assistance with daily living throughout t he nation . I am reaching out hoping that you might know to whom this message shoul d really go . Thanks again for all you do - and take care of yourse lf! The nation needs you. Sincerely, Linda NIH-000244 Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S Scientist Emeritus (Retired) Former Director, National Institute of Environmental Health Sciences and National Toxicology Program phone: (b)(6) cell (b)(6) (b)(6) e-mai l: personal email: (b) (6) """:"""--.-;::======--~~ ---------- From: (b)(6) Date: Monday, March 23, 2020 10:45 PM To: Linda Birnbaum Subject: Message to Dr. Fauci ----------- (b)(6)> Dear Dr. Fauci, The home care industry cares for tens of millions of our most vulnerable citizens in their homes every day. We provide assistance with activi ties of daily living and instrumental activities of daily living, which keeps our clients in their homes and in the lowest risk setting. Our professionalCaregivers are able and willingto continueto providecareto clients who test positive for COVID-19or have been exposedto the virus. But we need your help so that home care companies do not face unreasonab le liability for providing such care. To that end, we ask for your support in getting a bill through congress like the Public Readiness and Emergency Preparedness Act (PREPAct), 42 USC247d-6d, that will insulate providers like us from claims related to the care we will be providing in these extraordinary times. We also ask that you support creating a fund that will provide appropriate personal protective equipment to our caregivers. Our clients should not have to bear the additional burden of the added cost of PPE. Additionally, we would like you to encourage the CDCto clar ify its guidance on caring for COVID-19 patients (found here, here and here) that the guidance is applicable to "professional, licensed and insured, home based care agencies." This clarification will give the industry a workable standard to protect caregivers caring for COVID-19 clients. In essence, it would establish that facemasks and gloves are sufficient PPEto care for COVID-19 clients in the home, and not require its caregivers to comply with the healthcare sett ing requirements of wearing N95 respirators, eye protec tion (goggles or face shields) or gowns . This is important as a practical mat ter because respirators and gowns are not readily available at this time. Moreover, most home care workers are not tra ined in the proper use of respirators. Finally, we need your help in pressuring congress to provide day care for the children of our caregivers. If t hey cannot find adequate care fo r thei r children, then our clients will suffer. This is a vital step to keep our clients in the ir homes. NIH-000245 With you help, home care companies will be able to: l. Relieve the burden on the healthcare system by keeping our clients o ut of the hospita l; and 2. Adhere to shelter-in-place measures which w ill flatten the curve of COVID-19's spread. ~~~y L....:::J , On beha lf of: Michael Coccaro, Chief Operating Officer and General Counsel, Synergy Home Care Emma Dickison, Chief Executive Officer and President, Home Helpers Lisa Foster , Chief Clinical Officer, MGA Homecare Daniel Gottschalk, co-owner and President, Genova Health Margaret Haynes, Chief Operatin g Officer, Right at Home Vicki Hoak, Executive Director, Home Care Association of America Peter Ross, Chief Executive Officer and Co-Founder, Senior Helpers Timothy Ryan, Genera l Counsel, AccentCare, Inc. Shelly Sun, Founder, BrightStar Care (b)(6) www.nu rsecarenc.com www.livhome.com NIH-000246 NIH-000247 (bXS)- PCP. NIH-000248 NIH-000249 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:33:11 +0000 Barasch, Kimberly (NIH/NIAI D) [CJ FW: The global healt h leaders call, Wednesday 25 M arch at 13:00 CET (b)(4 Swisscom Call code.pdf Please print thi s out f or me for possibilit y doing th e call t omorrow . Thanks. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496 -4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: RYAN, Michae l J. (b)(6) Date: Tuesday, March 24, 2020 10:59 AM To: SHOC; Offi ce of t he Director-Gene ral ; Redfield, Robert R. (CDC/OD) (b)(6) ---~~~~~~~~~~~~~----~~~~~~~~~~~--; David _H_e..:. y_ m_a_n...; n=::====~~-:'.':"'"'."" (b '"'.'. )~C ; Felicity Harvey (b)(6)>; Chris.Elias (b)(6); (b)(6) J.Farrar --------; Fauci, An-t:ho_n_y-:{:N'."'."' IH:-: / :N:IA"".". ID :-:)-:-[:-: E]:-:===========-- (b)(6) =======~:;,,;;-_ ----============:::::::;.----=-=-= (b)(6) (b =-=)-:-= (6) GREIN, Thomas (b)(6)·>;COX, SCHWARTLANDER,Bernhard F. (b)( 6),; MINHAS, (b)( 6) '; Conrad, Patricia {NIH/NIA ID) [E] Raman (b)( ; M AHJOUR, Jaouad (b)(6b ; FALL, lbrahima Soce ====~~-----(b)(6) (b)(6); Thomas R. Frieden Lynn Banks (b)( ; President I Resolve to Save Lives ; (b)(6); AL-SHORBAJI, ---------- (b)(6); --==========~~----:----:--" Farah_=====~-~~------- Cb _>_<6) _.; Robynn Leidig (b)(6); DRURY, Patrick Anthony (b)(6),>; Dr VAN KERKHOVE, (b)(6) cherylc (b)( ; GRAAFF,Peter Jan (b)( ~ ; Tarik Mohammed (b)(6) Carlos Navarro Colorado ~ (b)(6) Ryan Morhard ;____;__::==-,;::,;;~--:-:-:-~ ======~--___:___ ___.:====~~ , =================~ ---------------------- NIH-000250 (b)(6) BRIAND,Sylvie ========,:~"""."".""----:--":"" ====== (b= )(=6)!.:. ;~H=arries, Jenny___ -:====== (b)( ; SIMONSON, Stewart =====~~~-(b)( 6) Jayatunga, Wikum !!===== ; Julie.HALL (b)(6}; (b)(6Jt>;MORGAN,Oliver (b=)(~6)::-; ~Awwad, David (NIH/NIAID) [C] (b)(6Jt>;SINGER,Peter Alexander (b)(6) (b)( Amelie RIOUX (b)(6) (b)(6); SHIN, Young-Soo (b)(6) Cc: SHOC; Office of the Director-General ; SCHWARTLANDER, Bernhard F. (b)(6); MAHJOUR,Jaouad (b)(6J:>; FALL,lbrahima Soce GREIN, Thomas (b)(6)·>; MINHAS, Raman (b)( ·; COX,Paul Michael (b)(6)r>; AL-SHORBAJI,Farah (b)(6J:>; POOLE,Marcia (b)( ·; DRURY,Patrick Anthony (b)(6J>; GRAAFF,Peter Jan =====:-=~ (b)(6) ; Dr VAN KERKHOVE, Maria (b)(6); KABIR,Sophia (b)(6)>; FARES,Christine Youssef (b)(6); AYLWARD , Raymond Bruce J. =====:-:-::!...,.; (b)(6) ·>; SMITH, Ian M ichael (b)(6) Subject: The global health leaders call, Wednesday 25 March at 13:00 CET (b)(6)·>; =====;:~,;-'" ------Dear colleagues, Dr Tedros would like to invite you to the next informal discussion about the ongoing 2019 novel coronavirus. The teleconference will be hosted on Wednesday, 25 March at 13:00 CET and the dial-in number with a passcode is attached. If you experience any technical difficulties joining this conference call, please contact the WHO HQ EOC operator at: +41227912490 It would be appreciated if you could kindly confirm your participation kabirso@who.int; mobile no. (b)(6) to Ms Sophia Kabir, email: Th e agenda and background documents will be shared ahead of the call. Best, Mike NIH-000251 Dear participant To join the upcoming teleconference, please call: From inside WHO (b)(4) From others countr ies please call: Country Argent ina Austra lia Austria Belgium Brazil Bulgaria Canada Chile China Croatia Cyprus Czech Republic Denmark El Salvador Estonia Finland France Germany Georgia Greece Hong Kong Hungary Ireland India Israel Italy Japan Kazakhstan Lathvia Lithuania Luxembourg Malaysia Malta Mexico Netherlands New Zealand Norway Panama Peru Philippines Poland Portugal Puerto Rico Russia Romania Singapore Slovakia Slovenia South Africa South Korea Sweden Switzerland (English) Switzerland (Italiano) Switzerland (Deutsch) Number +54 115 984 12 00 +61 280 147 967 +43 720 880 876 +32 280 835 50 +55 213 958 07 18 +35 924 917 399 +16136e6 43 59 +56 225 95 28 26 +86 105 789 7457 +38 51 777 63 03 +35 72 503 02 78 +42 024 €01 95 32 +45 699 182 15 +50 32 113 37 10 +37 26 68 12 68 +35 894 270 50 03 +33 1 77 69 68 25 +49 698 991 47 25 +99 57 067 773 41 +30 211 198 00 81 +85 258 084 851 +36180 881 90 +35 314 845 940 +9 1 11 712 79 153 +97 237 219 661 +39 02 479 211 40 +81 345 209 476 +771 727274 71 +3716 765 25 76 +37 052 05 89 83 +352 208 801 72 +603 921 220 20 +35 62 778 01 98 +52 554 E24 02 27 +3 1 108 920 271 +64 99 25 03 39 +4721018941 +507 836 51 38 +51 17 08 54 63 +632 2312215 +48 221 168 469 +351 308 800 872 +17 879 05 73 62 +749 540 220 27 +40318107181 +65 315 813 05 +42 123 300 69 18 +38 61 600 49 18 +27 10 590 11 04 +82 707 488 31 02 +46 840 309 949 +4 1 58 2€2 07 22 +4 1 58 2E2 07 44 +4 1 58 2€2 07 11 NIH-000252 Access Code (b) (4) (b) (4) Switzerland (Frangais) Spain Tadzhikistan Turkey United Kingdom United States +4 1 58 2€2 07 33 +34 931 816 661 +99 242 782 22 70 +90 21 290 025 60 +44 203 370 57 19 +16463810889 NIH-000253 From: Date: To: Subjec t : Fauci, Anthony (NIH/N IAID) [E) Tue, 24 Mar 2020 15:32:02 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: interview request Tell them no. Anthony S. Fauci, MD Director National Ins titute of Allergy and Infectious Diseases Bui lding 31, Room 7 A-03 31 Center Drive , MSC 2520 Nationa l Institu tes of Health Bet besda , MD 20892 -2520 Phone: (b) (6) FA X: (301) 496 -4409 E-mail: (b) (6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensi tive infom1ation. It should not be used by anyone who is not the original intended recip ient. l fyou have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Tue National lnstimt e of Alle rgy and Infe ctio us Diseases (Nl AID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NIAID by one of its representatives. -----Original Message----From: Raphael De Montferrand Date: Tuesday, March 24, 2020 11:27 AM To: Fauci, Anthony (NrH/NlAID) [E] (b)(6} Subject: interview reque st ------~~= dr Faucy , Hello, my channel is doing a section of its news tonight (at 3:45pm your time) on the coronavirns situation in New York . T wondered ifwe could interview you over skype. Do you think that might be poss ible at 3:45pm today your tim e? We have a simultan eous translator as we operate in trench from our stu dio in Pari s . Looking forward to hear from you, Raphael de Montferrand RT France 0033608662642 NIH-000254 Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:30:50 +0000 (b)( 6) Subject: FW: Boston Globe: In orde r to save Dr. Fauci, w e mu st destroy him Yikes! You have to read t his. Thi ngs are gettin g unbelievably crazy. Anthony S . Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301) 496-4409 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Folkers, Greg (NIH/NIA ID) [E] (b)(6) Date: Tuesday, March 24, 2020 10:16 AM To: NIAID OCGR Leg ; NIAI D OD AM ; NIAID COGCORE Subj ect: Boston Globe : In order to save Dr. Fauc i, we must destroy him In order to save Dr. Fauci, we must destroy him Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is a study of calm and competence in the middle of a pandemic. Which makes him an endangered species, working as he does for a boss who is notoriously insecure and made his name shouting "You're fired!" on a reality TV show. ByKevin Cullen Globe Column ist,Updated March 23, 2020, 5:25 p.m. 209 NIH-000257 Dr. Anthony Fauci's calm, reassuring competence in response to the coronavirus pandemic is placing him at serious risk of hearing the words tha t made his boss famous: You're fired.Jabin Botsford/The Washington Post Dr. Anthony Fauci is a bum. A quack, a snake oil salesman. He got his degrees on line, not from Holy Cross and Cornell. He watches Wheel of Fortune but not Jeopardy. He's a Yankees fan. Such character assassination is unsavory but necessary because Fauci's calm, reassuring competence in response to the coronavi rus pandemic is placing him at serious risk of hearing the words that made his boss famous: You're fi red . President Trump is watching and listening to the same thing we are, i.e., Fauci going to the podium to rebut with facts the latest outbreak of paranoid anxiety or the president'sr egu larly reckless statements. Fauci is an oasis of rigor and reason in a barren desert of confusion and fear. Which, given who he works for, makes him an endangered species. During the Vietnam War, some US Army officer supposedly suggested that in order to save a village from the Vietcong they had to destroy it. And so, to save Dr. Fauci, we must destroy him - at least in Trump's eyes. Now that might sound crazy, but we're dealing with a crazy president in crazy circumstances. It's not as if there's no relevant precedent here. Two words: Bill Bratton. Two other words: Rudy Giuliani. Who happens to be Trump's BFF. Before Giuliani grew old, deranged, and more qualified to be a spokesman for Miracle Ear than the president's lawyer, he was the reform -minded mayor of New York City. Rudy rode into Dodge, which is what Times Square resembled at the time, and vowed to clean it up. His hand-picked sheriff was Dorchester's own Bill Bratton. As police commissioner, Bratton did much to stem violent crime in the nation's biggest city, but even more rema rkably got his cops to reduce the incidence of more minor , so-called quality of life crimes that NIH-000258 had made New York less livable, from the tony sections of Manhattan to the Tony Fauci sections of Brooklyn. Bratton did his job too well. He ended up on the cover of Time magazine, hailed as the guy who pulled the worm out of the Big Apple. He became more popular than the mayor. This drove Giuliani nuts. Rudy had to be the smartest guy in the room, had to get all the credit. Sound familiar? So Bratton had to go. That wasn't Bratton's first rodeo. Long before he landed in New York, he became the face of progressive, modern policing in his hometown, the youngest-ever Boston Police superintendent. Police Commissioner Joe Jordan resented his overly-ambitious No. 2 so he busted Bratton. The point is, insecure bosses don't like being shown up by smarter, more competent subordinates. Small men make big mistakes. It may be too late to save Fauci. He just got the star treatment from Maureen Dowd in The New York Times. There used to be a thing called the Sports Illustrated curse, that after an athlete appeared on its cover his or her career tanked. Similarly, being in the Trump administration and getting praised by The New York Times is the kiss of death. Now, normally, you could print something in the Times and chances were the president wouldn't read it. He routinely dismisses the Gray Old Lady as fake news, except when his and his family's lousy books are mass- bought onto the newspaper's bestsellers list. He is not fond of polysyllabic words and prefers to get his news from "Fox & Friends" or whatever wh ite nat ional ist website his aide Stephen Miller might recommend. But Trump reads Mo Dowd because they have known each other forever and she writes about him at a nuanced, personal level that drives him especially cuckoo. We're way past the theoret ical here. Tony Fauci is in real danger, and by extension so are the rest of us who expect - nay, pray for - one person in the White House to be trustworthy and competent in a time of unprecedented crisis. So, again, repeat after me, Dr. Anthony Fauci is a bum. Long live the bum . Kevin Cullen is a Globe columnist. He can be reached at kevin .cullen@globe .com. Di claimer: Any third-party material in thi email has been shared for internal u e under fair use provisions of U. . copyright law, without further verification of its accuracy/veracity. It does not necessarily repre eat my views nor those of IAID, NIH HH , or the U.. government. NIH-000259 From: Fauci, Anthony (NIH/N IA ID) [E) Tue, 24 Mar 2020 14:13:33 +0000 Date: To: (b)(6) Subject: RE:Update #2: Traffic Advisory: Street Closures Thanks Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: -------------------------=-:-=, (b)(6) Date: Tuesday, March 24, 2020 10:01 AM -------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: FW: Updat e #2: Traffic Advi sory: Street Closures A lot of street closures. I don't think it wi ll inte rfere with your trip downtown, but just in case From: AlertDC Date: Tuesday, March 24, 2020 7:33 AM To: ------------------- (b) ~ > Subject: Update #2: Traffic Advisory: Street Closures This is an important message from the District of Columbia AlertDC system. On Tuesday , March 24, 2020, in coordination with the National Park Service, the Metropolitan Police Department will make several street closures beginning at 7:00 a.m. through approximately 8:00 p.m at the following locations: • The Memorial Bridge • Lincoln Memorial Circle • Potomac River Freeway (all exits to Ohio Drive and Independence Avenue) NIH-000260 • Rock Creek Parkway/Potomac Parkway Drive between Virginia Avenue and Independence Avenue , SW (to include Ohio Drive, SW) • Independence Avenue between Ohio Drive and 14th Street , SW • 23rd Street between Constitution Avenue and Lincoln Memorial Circle • Henry Bacon Drive between Constitution Avenue and Lincoln Memorial Circle • 17th Street between Constitution Avenue , NW and Independence Avenue, SW • 15th Street between Constitution Avenue , NW and Independence Avenue, SW • Maine Avenue between Independence and 12th Street, SW • All vehicular exits to East Potomac Park and West Potomac Park All street closures and listed times are subject to change based upon prevailing or unexpected conditions . The public should expect parking restrictions along the street and should be guided by the posted emergency no parking signage . All vehicles that are parked in violation of the emergency no parking signs will be ticketed and towed . Individuals and groups will encounter delays in the vicinity of this closure . To help flatten the curve , we strongly discourage any Tidal Basin visits because social distancing has not been possible due to visitor volume . For more information about the District 's coronavirus response , visit coronavirus.dc .gov Click Here to update your profile. To stop receiving future email notifications from this organization unsubscribe here . NIH-000261 From: Fauci, Anthony (NIH/N IA ID) [E) Date: Tue, 24 Mar 2020 14:12:54 +0000 To: Mi ller , Katie R. EOP/OVP Cc: Short , MarcT . EOP/OVP;Conrad, Patricia (NIH/N IAID) [E];Billet, Courtney (NIH/N IAID) [E];O'Ma lley, Devin M . EOP/OVP Subject: RE: Please advise I called the reporter and she was very receptive to my corrections of the record and presentation of the facts . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Be thesda MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: M iller, Katie R. EOP/OVP (b)(6)> Date: Tuesday, Mar ch 24, 2020 9:37 AM To: Fauci, Anthony (NIH/NIAID) [E) _.;....;....:.:::::=====~~ Cc: Short , Marc T. EOP/OVP Cb)( >; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Billet , Courtney (NIH/NIAID) [E) (b)( O'Ma lley, Devin M. ":E-:0-P7/ 0'.""'.' V"".": P---::======---.;._(b ""')""'(~ > ------~~ Subject: Re: Please advise (b)(5) Sent from my iPhone On M ar 24, 2020, at 9:27 AM, Fauci, Anthony (NIH/NIAID) [E] w ro te: Marc/Katie: NIH-000262 -------- CbH > (b) (5) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 (b)(6) E-mail: The information in this e-mail and any of its attachments is confident ial and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------- From: Abuta leb, Yasmeen Date: Tuesday, March 24, 2020 9:05 AM To: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Cc: Parker, Ashley Subject: Washington Post fact check on Fauci/scientists story --------~~ Hi Patty, Thanks very much for your help yesterday and hope you' re doing well . We're working on a story today about Trump's re lationship with the scientific and medical experts in the coronavirus response, including Dr. Fauci. We're reporting t his out today but wanted to send you what we've been hear ing as we get it so there's ample time to fact check everything today. Here are some points we'd love to discuss with the best person in your office or, better yet, Dr. Fauci himself . NIH-000263 • Fauci was apoplectic about Trump's tweet yesterday saying the cure couldn' t be worse than the virus and indicating that he wants to reopen businesses soon. • Fauci has been forceful privately that unproven drugs should not be advertised to Americans as a panacea (and he of course has publicly spoken about these drugs). • We are also reporting in a separate story that Larry Ellison is building a website for the federal government that will collect data on the efficacy of remdesivir, chloroquine and hydroxychloroqulne. our understanding Is Fauci is vehemently opposed to this idea and has pushed back on it, citing patient privacy concerns with the website and collecting data in this way outside of an approved FDA trial. Again, we'd love to speak with Dr. Fauci and any others in your office who may have insight into these particular issues and other aspects of the coronavirus response. Pleasefeel free to give me a call on my cell at any time at (b)(6) Thanks very much, Yasmeen Abutaleb The Washington Post Healt h policy reporter o: 202-334-8387 c: ___ """ (b)""'(=6) @yabutaleb7 NIH-000264 From: Date: To: Subjec t : (b)(6) Tue, 24 Mar 2020 07:47:49 -0400 Pottinger, Matthew F. EOP/WHO Re: regarding masks and Covid-19 Very good point. (b)(5)- PCI NIH-000265 (bX5)-PCE NIH-000266 NIH-000267 NIH-000268 From: Date: To: Subject: (b)(6) Mon, 23 Mar 2020 15:45:21-0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: Media Request:NPR'slA Show Begin forwardedmessage: From: Am anda Williams Date: March 23 , 2020 at 3:41:06 PM EDT To: "Fauci , Anthony (NIH/NIAID ) [E] " (b)(6Ji Cc: "NIAID NEWS (NIH/NIAID)" Subject: Media Req uest: NPR's lA Show ------~~ Hello Dr. Fauci, I'm a producer with National Public Radio's 1A show and we'd like to invite you to join our program to talk about coronavirus in the near future. We've bui lt our show on answering our 4+ million listeners' questions and we know Americans have a lot of questions for you right now. We don't take live calls, but we do curate input from voicemails and social media. We would love to have you join us. Please let me know if you are available and interested anytime soon. We are very flex ible. A bit more about 1A: We launched in January 2017 and we're ranked among the top 10 public radio programs on a list that includes Morn ing Edition, All Things Considered and Marketplace. We reach 4+ million listeners every week and air on more than 365 stations across the country. Our major markets include Chicago, LA, NYC, DC, At lanta, Boston, Philadelphia, San Francisco, Miami, Houston, Minneapol is and Seattle. Best, Amanda Amanda Williams Across America Producer lA, from WAMU and NPR (b)(6) (c) I @amandwms ----- I thela.org NIH-000269 Fauci, Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:32:28 +0000 (b)(6) (b)(6) Subject: Re: USA Today/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Attachments: im age002.jpg Love you all On Mar 23, 2020, at 3:0 7 PM , --------------- (b)(6)1 wrote: So True! In a message dated 3/23/2020 2:06: 15 PM Easte rn Standard Time, --------- Cb)(6) writes: Lots of a very kind and thoughtful and well-earned words of respect coming your way Cb) (6) On Mon, Mar 23, 2020 at 12:35 PM wrote: That' s a very nice piece about you, ------------ (b)( Cb) (6) I hope you got some rest this weekend. Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID) [E] Cb>< wrote: --------- Wow. David Rubenstein nice to me. ---- (b)(6) used to work for him) was really From: Folkers, Greg (NIH/NIAID) [E] Cb)(6) Date: Sunday, March 22, 2020 11:36 AM Subject: USA Today/David M. Rubenstein-- Corona:virushero: Anthony Fauci is a great public servant in a time of grea t pub lic need NIH-000270 Coronavirus hero : Anthony Fauci is a great public servant in a time of great public need Fauci is the world's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opin ion contrib utor Some viewers of the daily White House coronav irus briefings may wonder why everyone increasingly defers to a diminutive, Brooklynaccented 79-year -old doctor , Tony Fauci. They do because , as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American peo ple - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same workaround-the-clock, j ust-the-facts ma 'a m style that he has used while serving under and working with six U.S . presidents. He is as apolitical as anyone can be. I have no idea ifhe is registered with any poli tical party; I suspec t though that he is rabidly Independent. His only focus is getting the facts out, provid ing the best health care treatment and info1mat ion possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the Na tional Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the Nat ional Institute of Allergy and Infectio us Disease since 1984 - 36 years . Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge - malaria , NIH-000271 Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals , has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR), which has transformed the treatment of HIV /AIDS in Africa, and other parts of the developing world. Millions of lives have been save d by this program alone. More recently , he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S . through HIV antiretrov iral therapy targeted to disease hot spots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before ass uming his current role), Tony has received, and earned, the Presidential Meda l of Freedom and a Lasker Award (called the American Nobel by many). With this long service and universa l acclaim, one migh t think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same hou se he bought when he first moved to Washington , and it is there that he and his wife Christ ine have raised their three talented daughte rs (thoug h none of them chose to atte nd med ica l school). Unt il the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Was hington area or on Capito l Hill, he invariab ly turns down a car and driver for the Metro . (This practice has had to change of late for the obv ious reasons). The re are, of course, many other dedicated federa l serva nts who also view their comm itment to the countr y and its people over financial rewards. But surely no federa l civil servant , in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. NIH-000272 I tried years ago, when Tony was approac hing a normal retireme nt age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quick ly said no - money did not motivate him, serving the coun try did. And he stayed at NIH - to the country's good fo1tune. If there is any one medica l profess ional who can he lp the country deal with the COVID - 19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauc i has the decades of experience needed to understand infectious disease prob lems and prescribe a trea tment that shou ld, in time , prov ide the requisite comfort , even if, in the short term, the med icine is painfu l and inconve nient. David M Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, wit hout further verification of its accuracy/veracity. It does not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. (b)(6) NIH-000273 NIH-000274 NIH-000275 From: Date: To: Cc: Subject: (b)(6) Mon, 23 Mar 2020 15:16:17 -0400 Barasch, Kimberly (NIH/NIAID) [CJ Conrad, Patricia (NIH/NIAID) [El Fwd: Me eting on the science of COVID-19, Wed. 3/25, 2 - S pm Please print out for me and have ready in case I do this on Wednesday Begin forwarded message: From: "Tromberg, Bruc e (NIH/NIBIB) [E]" (b)(6)> Date: March 23, 2020 at 1:22: 18 AM EDT To: "Collin s, Francis (NIH /OD) [E]" Cc: "Tabak , Lawrence (NIH /OD) [E]" Anthony (NlH/NIAID) [E]" (b)C > Subject: Re: Meeting on the science of COVID-19, Wed. 3/25, 2 - 5 pm -------=-=-= Hi Francis, Thanks, I'm looking forward to the meeting. Probably not directly relevant to this upcoming discussion, (b)(S) (b)(S) NIH-000276 (b) (5) Best, Bruce From: "Collins, Francis (NIH/OD) [E]" (b)(6) Date: Sunday, March 22 , 2020 at 9:38 PM To: "ICDDIR-L@LIST.NIH.GOV " Cc: "Tabak, Lawrence (NIH/OD) [E]" (b)(6) "Wolinetz, Carrie (NIM/OD) [E]" (b)( , "Anderson, James (NIH/OD) [E]" (b)(6), "Parker, Ashley (NIH/OD) [E]" 7 (b) ;;(6) ;:;->,-::"-:" McManus, Ayanna (N IH/OD) IE]" =~===~ (b)(6), "Wood, Gretchen (NIH/OD) [E]" ======::e (b :c,;: )::,:,, (6) :c;--- $.~bject: Meet ing on the science of COVID-19, Wed. 3/25, 2 - 5 pm Colleagues, I'm glad to hear that most of you are able to join a three -hour virtual meeting on Wednesday March 25 to discussscientific opportunities in the effort to conquer the COVID-19 pandemic. While NIAID rightly has the lead in this effort for NIH, and is deeply invested in projects in both their intramural and extramural programs, it' s clear that a number of other ICs have creative ideas and a strong motivation to try to help with this global crisis. So this certainly seems like a time where we should gather (virtually of course) NIH-000277 to brainstorm together, led by NIAID, and seek to identify any additional areas of contribution that could be subject to acceleration and/or collaboration. Hilary Marston recently convened a Deputies meeting on this subject, and ICs were then asked to submit examples last Friday of projects they are pursuing in the COVID-19 space. Those were forwarded from Bob Eisinger to me. I have used those submissions, including a detailed list of NIAID projects, to put together a tentative agenda for Wednesday's meeting . That is attached. (b) (5) There are admittedly a lot of themes and topics here, so this will require some real discipline in the one -slide presentations . I will try to serve as time -keeper- or maybe I'll ask Larry to do that. □ D All IC Directors are invited to have one or two subject matter experts join them for this virtual discussion. Ashley Parker (b)(6) will be helping me with the logistics and will have further instructions about how the log in w ill work. Here's the specific follow up request that needs your immediate attention : 1. If your IC is pursuing a highly relevant project that's not listed here, and that you want the group to hear about, please send me that informa ti on ASAP. 2. If your IC is on t he draft agenda to make a presentation, please submit your one slide (except for NIAID, who gets more) to me and Ashley by COBTuesday 3/24. That way we can put the whole set together as a single ppt file. Many thanks! This should provide a welcome respite from the many other tasks we are all facing right now . Francis NIH-000278 Fauci,Anthony (NIH/NIAID) [E) Mon, 23 Mar 2020 19:06:06 +0000 Bee: Aberg, Judith;Adaora Adimora;Grund, Birgit;Glidden, David;Daar,Eric;Erica Hardy;Gandhi, RajeshTim,M.D.;JasonBaker;JeffLennox;Johnson,Steven C- ID;Kim,Arthur From: Date: Y.,M.D.;Marla Keller;Tebas, Pablo (NIH );Susan Davis;Susan Swindells;Susanna Naggie;Tien, Phyllis;Amy Dzierba;Mitchell Levy;Laura Evans;Cra ig Coopersmith ;Greg Martin;Uyek i, Timothy M . (CDC/0010/NCIRD/ ID);Walker, Robert (OS/ASPR/BARDA);Sheikh, Virginia (FDA/CDER);Anne Collie r;Francis, Joe (Contact NLM/OD -External) (b)(6) Subject: Invitation to j oin the HHSPanel on Guidelines for The Management of COVID-19 Dear Colleague , At the request of the Office of the Secretary, HHS and in conjunction with the White House Task Force we are creating a COVID-19 management guidelines panel to provide frequently updated information to the pub lic regarding the treatment of patients with COVID-19. This guidance will be an HHS document, will be updated frequently and will be modeled to some degree after the ART guidelines. The Panel will include academicians and clinicians currently caring for persons with COVID-19 and representatives from multiple US government agencies (CDC, BARDA, FDA, VA, DoD) and professional societies. Cliff Lane, M.D . Henry Masur, M .D. and Trip Gulick, M.D . will co-chair, and Alice Pau, Pharm.D . will be the exec. sec. for this new panel. Those of you who are appointed to represent your federal agencies will be ex officio. Other federal employees will be vot ing members. I would like to invite you to be a member of this new Panel based on your expertise. We anticipate that work will begin this week and we hope to be able to put out the first guidance in 1-2 weeks. We appreciate your will ingness to jo in this very important effort and your work in caring for pat ients during th is pandemic. The first meeting (by teleconference) will be Tuesday , March 24 at 11:00AM EDT. More details will be provided soon. Thank-you for considering this and for all you are doing during this most challenging time. Sincerely, Anthony S. Fauci, MD Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 NIH-000279 Phone: (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any othe r storage devices . The Nat ional Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000280 Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 Mar 2020 18:38:21 +0000 From: Date: To: (b)( 6) (b)(6) Cc: RE: FW: USA Today/David M. Rubenstein-- Coronavir us hero: Anthony f-auci is a great public servant in a time of great public need Subject: Love you all. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)( 6) FAX: (301 496-4409 E-mail=--....,. _. _, (b)(6) The information in t ,s e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6)> Date: Monday , Mar ch 23, 2020 12:35 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) > (b)(6) Subject: Re: FW: USA Today/Dav id M. Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a t ime of great publ ic need ~ (b)=(6) = That 's a very nice piece about you, I hope you got some rest this weekend . Sending lots of love. On Sun, Mar 22, 2020 at 6:34 PM Fauci, Anthony (NIH/NIAID ) [E] Wow. David Rubenstein ---- (b)(6) -------- (b)(6)> w rot e: used to work for him) was really nice to me. From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Sunday, Marc h 22, 2020 11:36 AM Subject: USAToday/David M. Rubenste in-- Coronavirus hero : Anthony Fauci is a great public servant in a time of great publ ic need NIH-000281 Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the world 's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M . Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminutive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recently interviewing this man, he is without doubt the world 's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard . In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around-the -clock, just-the-facts ma'am style that he has used while serving under and working with six U.S. presidents. He is as apolitical as anyone can be. I have no idea if he is registered with any political party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top expert from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period, he has dealt with every serious infectious disease challenge malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, late r, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots . In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of th e enti re medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Award (called the American Nobel by many). With th is long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though . Selfless commitment to public service NIH-000282 He is readily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wife Christine have raised their three talented daughters (though none of them chose to attend medical school). Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running three miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver for the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards. But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this country and the health of its people. I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not motivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19 crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a treatment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient. David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It docs not necessarily represent my views nor those of NIAID, NIH, HHS, or the U.S. government. Ali Fauci NIH-000283 From: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 18:14:25 +0000 Barry Albertson RE:Pooled $maples Date: To: Subject: Thanks, Barry. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . From: Barry Albertson Date: Monday, March 23, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Pooled Smaples Import ance: High -------=-=--== (b)(6)> Hi Tony, I'm forwarding an email I just sent to Paul Cieslak, MD .....one of the lead docs at the Oregon Health Author ity CbH6l ; he gives my clinic's Internal Medicine docs an 'ID Update' for my CME Grand Rounds each yea r) ...with this email note from Dr. David Brandon ...hope you remember David....he was w ith Lynn's & Mort Lipsett's group at The Clinical Center . ...I'd bet a coke you know all about pooled sampling .....but wanted to pass it along. You have no idea how many people tell me tha t your COVID-19 messages on TV, etc. are top flight , enormously helpful and encourag ing for them with the best information , in a sea now of poor information . NIH-000284 Andrew Cuomo is also doing a great job informing all of NY (and the rest of us) about what's going on, and his expectations for the public. Whatever they're paying you ... it's not enough. You keep your powder dry, and extra flints in your pocket! Barry From: Barry Albertson Date: Monday, March23, 2020 9:49 AM To: 'CieslakPaul R' Subject: PooledSmaples Importance: High Good morning, Paul. Hope you guys at OHA are holding up OK. I'm fine , fam ily is fine. .. (b)(6) is dong lots of te lemedicine and seeing act ual PEDS patients at Westside Hosp. now a few days a week. My clinic is still open but pretty quiet ... we need to stay open at some level no matter wha t . ------- One of my colleagues from the NIH (Dr. David Brandon ...he actually published with Tony Fauci back in t he late '70s I believe !) ..sent me this email on Saturday morning I suspect you all know about poo led sampling, .....David did it at the NIH for a study that I have long forgotten about. ...thought I'd pass it along to you ...... " I just looked up to see if pooled sampling has been used t o detect viruses in the past, and found that it has been used in a number of cases including during the HIV scare. I am including a Iink thttp s://www. israel2 lc. org/israelis-introd uce-method-for-accel erated-covid-19testing/ to an article in the lay press reporting on an RT-PCRbased test that uses swabs from 30-60 individuals to dete rmine if the pooled sample has Covid-19. The study was successful and they are developing it to test workers in the front line work places such as hospitals. There is a body of literature using t his method for other mass screenings." Then I heard that CEPHEIDwill be getting their Genexpert instrument validated to measure COVID-19. Turns out we have one in my Lab, use it for Chlamydia & Gonorrhea (we have lots of patients here needing this testing). But as you so well know, having the inst rumentation without the collection swabs/M4 media, etc. Is a bit like biking up a blind alley. I would hope we'll hear more about t his. NIH-000285 Give me a shout if I can do anything to help you all out of your way! Barry NIH-000286 ...... best tack for me, I believe, is to stay (b)(5)- PCR NIH-000287 From: Date: To: Subject: Fauci, Anthony (NIH/N IA ID) [El Mo n, 23 Mar 2020 18:09:12 +0000 O'Grady, Naomi (NIH/CC/CCMD) [El RE:vent rat ioning Naomi : I am not aware of any efforts on rationing ventilators . They speak of mak ing sure the high priority areas such as NYCget what they need, but there is no ta lk at this t ime of "rationing" Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: O'Grady, Naomi (NIH/CC/CCMD) [El Date: Monday, March 23, 2020 1:53 PM --------Fauci, Anthony {NIH/NIAID) [El------~~ -------Subject: vent rationing To: (b)(6b (b)(6)> Hi TonyI know you are very busy but I wanted to see if you know of any effort on t he part of the federal government to issue guidance on the rationing of ventilators when the time comes? Many of my colleagues in critical care across t he country have been asking for some such guidance on a federal level. Both for the guidance itself and to protec t themselves from legal liability. Are you aware of any such efforts? Thanks for any insights on t his. And thanks for all you are doing on the coronavirus effort! Best regards, Naomi Naomi P. O' Grady, MD Chief, Internal Medici ne Services NIH Clinical Center NIH-000288 Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 16:48:31 +0000 Dan Hurley Conrad, Patricia (NIH/NIA ID) [El RE:2 questions from NY Times Mag reporter who int erviewed you about EV- From: Date: To: Cc: Subject: D68 Dan: Thanks for the note . The work on an EV-D68 vaccine will continue . The Coronavirus vaccine research is the highest prio rity. Both come out of Barney Graham's group in our VRC. Best to call Barney about the degree of possible interference. Books are not on my mind right now. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Dan Hurley (b)(6) Date: Monday, Mar ch 23, 2020 11:46 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6>:> Subject: Re: 2 questions from NY Times Mag reporter who inte rviewed yo u about EV-D68 ------~~ Hi Dr. Fauci and Patty: In addit ion to the two items mentioned in my original email, the NY Times Magazine is also interested in publishing an interview wit h Dr. Fauci. Thank you, Dan Hurley On Thu, M ar 19, 2020 at 6:04 PM Dan Hurley --------- (b)(6) wrot e: Hi Dr. Fauci: I interv iewed you by telephone a few months ago for an article in the New York Times Magazine about enterovi rus D68, the putative causal agent of acute flaccid myelitis. At the t ime you said that NIAID was work ing hard on developing a vaccine for EV-D68. I have two questions: NIH-000289 1. Is work on developing a vaccine against the novel coronav irus interrupting or slowing work on EVD68? Hard to believe it wouldn't have an effect . 2. When things calm down with COVID-19, would you consider allowing me to write a biography about you, or helping you write a memoir? This pandemic has kind of turned you into the face of medical science in the United States. I'm the author of four prior science books, and have profiled countless scientists in the Times, The Atlantic, and elsewhere. I know this is not the time for such things. I just want to put the idea out there . I hope and pray you do not find it offensive for me suggest such a thing at this time of danger and stress. Let me know about that EV-D68 vaccine if you can. I'm also reaching out to Barney Graham. Thank you, Dan Hurley NIH-000290 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 14 :51:53 +0000 (b)(6) FW : Dinarello Proposa l Dinarello Proposal for COVID-19.doc Cliff : (b)(5 Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please info rm the sende r and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infecti ous Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: char les dinarello (b)(6)> Date: Sunday, Marc h 22, 2020 9:31 PM To: Fauci, Anthony (NIH/ NIAID) [E] Subject: Dinarello Proposal -------~~ --------- (b)(6) (b)(6) I watch CNN almost constantly to listen to your impress ive wisdom . The world listens to you. Shelly would be so proud of you in this world crisis as he was in the HIV-1 crisis. We will not see each other at the National Academy of Sciences meeting end of April, but hopefully next year. I very much enjoyed hearing you place the anecdotal use of chloroquine in its correct context. "Chloroquine is an awfu lly blunt tool and an indication of our desperation" , Peter Libby 4> wrote me recently. Tony, attached is a propo sal CbH I need your guidanc e. I know you are terribly busy so I am copying Cliff. If there is anyone else who can help me, just forward the attachment. (b)(6) NIH-00029 1 From: Date: To: Fauci, Anthony (NIH/NIAID) [E) Mo n, 23 Mar 2020 14:48:07 +0000 Cc: Conrad, Patricia (NIH/NIAID) [El FW: 23-3-2020 FAO Dr Birx and Dr Fauci - Covid -19 Task Force RE:- Favipiravir = Subject: (b)(6) Avigan Please have someone handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b)(6Ji Date: Monday, March 23, 2020 8:32 AM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: NST Rogers (b) (6) Subject: 23-3-2020 FAQ Dr Birx and Dr Fauci - Covid-19 Task Force RE:-Favipirav ir = Avigan Importance: High 23-3-2020 Dear Dr Birx and Dr Fauci, As promised, sorry about the delay. Please see below two articles relating to Favipiravir wh ich has the brand name Avigan. This appears to have some beneficial effects with regard to the treatment of Covid-19. I have also included the Wikipedia for Favp iravir . Good Luck w it h regard to managing the epidemic/pandemic. NIH-000292 Yours Sincerely Nicholas Rogers Favipiravir Drug Description Favip iravir, also known as T-705, Avigan, or favilavir is an antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses . Like certain other experimental antiviral drugs, it is a pyrazinecarboxamide derivative. Wikipedia Formula : C5H4FN3O2 ChemSpider ID: 431002 ChemSpider ID: 431002 PubChem CID: 492405 Favipiravir From Wikipedia, the free encyclopedia Jump to navigationJump to search Experimental antiviral drug with activity against many RNA viruses. Favip irav ir 0 FYi N~ l ,c; N OH Names lUPAC name 6-Fl uoro-3-hydroxypyrazine-2-carboxamide Other names T-705; A vigan; favilavir Identifiers NIH-000293 CAS umber • 259793-96-9 3D model (JSmol) • Interactive image ChEMBL • ChEMBL22 l 722 Chem Spider • 431002 PubChem CID • 492405 UNII • EW5GL2X7E0 ✓y CompTox Dashboard (EPA) • DTXSID60948878 , In hi[ how] In hl= I / 5H4FN3O2/c6-2-1-8-5( 11)3(92)4(7) I 0/h I H,(H2,7, I 0)(H,8, 11) Key: Z NOVWY BHAU -UHFFFAOY A- N In hI= I/ 5 H4FN3O2/c6-2-1-8-5( I I )3(9-2)4(7) I 0/h I H,( H2,7, I 0)(H, , I I) Key: Z GNOVWY BHAU -UHFFFAOYAM SMILES[ how] Oc I ncc(F)nc I (=O) Propert ies hcmical fon11ula Molar ma 5H4F 30 2 157. 104 g ·mol- 1 Pharmacology AT code J05AX27 (WHO) Except where otherwi e noted , data are given for materia l in their tandard late (at 25 °C [77 °F], 100 kPa). Infobox reference Favip irav ir al o known a T-705 , Av igan or fav ilavir i an antiviral drug being developed by Toyama hemical (Fujifilm group) of Japan with activity against many RNA viru e . Like certain other experimental antiviral drug (T-1 105 and T-1106), it i a pyrazinecarboxamide derivative. In experiment conducted in animal Favipiravir ha hown activity again t influenza viru e We t Nile viru , yellow fever virus, foot-and-mouth di ea e virus as well a other flaviviru e , arenaviru e , bunyaviru e and alpbaviru e _[I] Activity again t enteroviru e [2] and Rift Valley fever virus ha al o been demon tratect.Pl Favipiravir ha howed limited efficacy again t Zika viru in animal tudie , but wa le effective than other antiviral uch a MK608.[4] The agent ha al o hown ome efficacy again t rabie [SJ and ha been u ed experimentally in some human infected with the viru .[61 In February 2020, Favipiravir wa being tudied in China for experimental treatment of the emergent COVID-19 (novel coronaviru di ea e).P l[S] On March 17, Chine e officials uggested the drug had been effective in treating OVID in Wuhan and ShenzhenJ 9HIO] As of 23 March 2020, it eems that Japan and China have i sued an export ban on the ub tance. Japan and hina are the only countrie in which favirapir i produced and approved a a medical NIH-000294 compound. Some Chinese pharmaceutical companies assure that export rights are still granted via international diplomatic means by the Chinese Ministry of Industry and Information Technology (MIIT). ll Contents • • • • • • !Mechanism of action 2Approval status 3Ebola virus trials 4Coronavirus disease 2019 (COVID-19) 5See also 6Refe rences Mechanism of action[edit] The mechanism of its actions is thought to be related to the selective inhibition of viral RNAdependent RNA polymerase.[ 1 I] Other research suggests that favipiravir induces lethal RNA transver sion mutations, producing a nonviable viral phenotype.(1 2] Favipiravir is a prodrug that is metabolized to its active form, favip iravir-ribofura nosyl-5'-trip hosphate (favip iravir-RTP), available in both oral and intravenous formulations.[ I3J[t4 ] Human hypoxanthine guanine phosphoribosyltransferase (HGPRT) is believed to play a key role in this activation process_[IS] Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them_[l] In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics. [161However, favip iravir has not been shown to be effective in primary human airway cells, cast ing doubt on its efficacy in influenza treatment. [ 17] Approval status[edit] In 2014, Japan approved Fav ipirav ir for treating viral strains unresponsive to current antivirals.l 18l Toyama Chem ica l initially hoped that Avigan would become a new influenza drug that could replace Tamiflu. However , animal exper iments show the potential for teratogenic effects on fetuses, and the approval of production by The Ministry of Health , Labor and Welfare was greatly delayed and the production condition is limited only in an emergency in JapanV 9 l In March 2015, the US Food and Drug Administration completed a Phase III clinical trial studying the safety and efficacy of Fa vipiravir in the treatment of influenza. [20] NIH-000295 On March 15, 2020 the drug was approved in China with the name Favilavir for the trea tment of influenza .[2 I] The drug was also approved for use in clin ical trials for treating coro naviru s disease 2019 pneumonia .[21] On 22 March, 2020 Italy has ap proved the drug for exper imental use against COV ID-19 and has begun conducting trials in 3 regions most affected by the disease. [22 l The Italian Pharmace utical Agency , however, has reminded the public that the existing evidence in support of this drug is scant and prel iminary.[23 ] Ebola virus trials[edit] Some research has been done suggesting that in mouse models Favipiravir may have efficacy against Ebo la. Its efficacy against Ebola in humans is unproven_[24][25][26] During the 2014 West Africa Ebo la virus outbreak, it was reported that a French nurse who contracted Ebola while volunteering for MSF in Liberia recovered after receiving a course of favipiravir. [27l A clinical h·ial investigating the use of favipiravir against Ebo la virus disease was started in Gueckedou, Guinea, during December 2014.( 281Preliminary results showed a decrease in mortality rate in patients wit h low-to-moderate levels of Ebola virus in the blood, but no effect on patients with high leve ls of the viru s, a group at a higher risk of death.[29] The trial design has been critic ised by Scott Hammer and others for using only histor ica l conh·ols.[30] The results of this clinical trial were prese nted in February 2016 at the annual Conference on Retroviruses and Opportunist ic Infections (CROI) by Daouda Sissoko[3l] and published on March 1, 2016 in PLOS Medicine. [321 Coronavirus disease 2019 (COVID-19)[edit] On 17 Marc h 2020, Chinese offic ials suggested that Favip iravir seemed to be effective in treating COV ID-19 in Wuhan and Shenzhen_[33 J[34 ][ 35] A study on 80 patients comparing it to lopinavir/ritonavir found that it significantly reduced viral clearance time to 4 days, compared to 11 for the control group, and that 91.43% of patients had improved CT scans with few side effects.P 6J[37] As of 23 March 2020, it seems that Japa n and China have issued an export ban on the substance . Japan and China are the only cotmtries in which favira pir is produced and approved as a med ical compound. Some Chinese pharmaceutical companies assure that export righ ts are still granted via interna tional diplomat ic means by the Chinese Ministry of Industry and Informat ion Technology (MIIT).[citario1111eede ,1] See also[edit] NIH-000296 • • • • • • • • BCX4430 Brincidofovir FGI-106 JK-05 REGN-EB3 TKM-Ebo la Triazav irin ZMapp References [edit] 1. 2. 3. 4. 5. Jump up to: a b Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD (June 2009). "T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections". Antiviral Res earch. 82 (3): 95- 102. doi:10.1016/j.antivira/.2009.02.198. PMID 19428599. /\ Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL (November 2013). "Favipiravir (T- 705), a novel viral RNA poly merase inhibitor". Antiviral Research. 100 (2): 446- 54. doi:10.1016/j.antiviral.2013.09 .015. PMC 3880838. PMID 24084488. /\ Caroline AL, Powell DS, Bethel LM, Oury TD, Reed DS, Hartman AL (April 2014). "Broad spectrum antiviral activity of favipiravir (T-705): protection from highly lethal inhalational Rift Valley Fever". PLOS Neglected Tropical Diseases. 8 (4): e2790. doi:l0 .1371/journal.pntd.0002790. PMC 3983105. PMID 24722586. I\ Mumtaz N, van Kampen JJ, Reus ken CB, Boucher CA, Koopmans MP (2016). "Zika Virus: Where Is the Treatment ?". Current Treatment Options in Infectious Diseases. 8 (3): 208- 11. doi:10.1007 /s40506-016-0083-7. PMC 4969322. PMID 27547128. /\ Yamada K, Noguchi K, Komeno T, Furuta Y, Nishizono A (April 2016) . "Efficacy of Favipiravir (T-705) in Rabies Postexposure Prophy laxis". The Journal of Infectious Diseases. 213 (8): 1253- 61. doi:10 .1093/infdisljiv586. PMC 4799667. PMID 26655300. A I\ Mwphy J, Sifri CD, Pruitt R, Hornberger M, Bonds D, Blanton J, Ellison J, Cagnina RE, Enfield KB, Shiferaw M, Gigant e C, Condori E, Gruszynski K, Wallace RM (January 2019). "Human Rabies - Virginia, 2017". MMWR. Morbidity and Mortality Weekly Report. 67 (5152) : 1410- 14. doi:10.15585/mmwr.mm675152a2 . PMC 6334827. PMID 30605446. 7. I\ Li G, De Clercq E. Therapeutic options for the 2019 novel coronav irus (20 19-nCoV) . Nature Reviews Drug Discovery 2020 Feb doi: 10.1038/d41573-020-00016-0 8. I\ BRIEF -Corrected -Zhej iang Hisun Pha1ma gets approval for clinical trial to test flu drug Favipiravir for pneumonia caused by new coronav irus. Reuters Healthcare, February 16, 2020. 9. I\ NHK World News 'China: Avigan effective in tackling coronavirus ' 10. /\ Huaxia. "Favipiravir shows good clinical efficacy in treating COVI D-19: officia l." Xinhuanet.com, 17 March 2020 6. NIH-000297 Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J (2013). "The ambiguous base -pairing and high substrate efficiency o.fT-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase". PLOS One. 8 (7): e68347. Bibcode:2013PLoSO ... 868347J. doi:l0.1371/journal.pone.0068347. PMC 3707847. PMID 23874596. 12. A Baranovich T, Wong SS, Armstrong J, Marjuki H, Webby RJ, Webster RC, Govorkova EA (April 20 13). "T- 705 (favipiravir) induces lethal mutagenesis in influenza A HlNl viruses in vitro". Journal of Virology . 87 (7): 3741- 51. doi:10 .1128/JVI.02346-12 . PMC 3624194. PMID 23325689. 13. A Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen TH, R odallec A, et al. (March 2018). "Antiviral efficacy offavipiravir against Ebola virus: A translational study in cynomolgus macaques". PLOS Medicine. 15 (3): el 002535. doi:10.l 37 l/journaL.pmed.1002535. PMC 5870946. PMID 29584730. 14. A Smee DF, Hurst BL, Egawa H, Takahashi K, Kadota T, Furuta Y (October 2009). "Intracellular metabolism offavipiravir (T- 705) in uninfected and influenza A (H5Nl) virus-infected cells". The Journal of Antimicrobial Chemotherapy. 64 (4): 741- 46. doi:10.1093(jac/dkp274. PMC 2740635. PMID 19643775 . 15. A Naesens L, Guddat LW, Keough DT, van Kuilenburg AB, Meijer J, Vande Voorde J, Balzarini J (October 2013). ''Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)". Molecular Pharmacology. 84 (4): 615- 29. doi:10 .1124/mol.113.087247. PMID 23907213. 16. A Koons C (7 August 2014). "Ebola Drug From Japan May Emerge Among Key Candidates". Bloomberg. com. 17. A Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Lu czo JM, et al. (August 2018). "Orally Efficacious Broad-Spect rum Ribonucleoside Analog Inhibitor of Influenza and R espiratory Syncytial Viruses". Antimicrobial Agents and Chemotherapy. 62 (8): e00766-18 . doi:10 .1128/AAC.00766-18. PMC 6105843. PMID 29891600. 18. A Hayden, Frederick (2019). "Influenza virus polymerase inhibitors in clinical development". Current Opinion in Infectious Diseases . 32 (2): 176-186. doi:10.1097/QC0.0000000000000532. PMC 6416007. PMID 30724789. 1 19. A ~l!/=fif ~:#KJP.r!-!f &/::}Et; tt- li'tl.!ft~-1':.,, 7 J~Jf!(l)"!/!t✓-£''. Retrieved 25 Februa,y 2014. 20. A "Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316". FDA. Retrieved 17 March 2020. 11. A Jump up to: 0 b J!,%-rffi "Potential coronavirus drug approved for marketing Chinadaily.com.cn". www.chinadaily.com.cn . Retrieved 2020-03 -21. 22. A "Coronavirus, il Veneto sperimenta l'antivirale giapponese Favipiravir. Ma l'Aifa: "Ci sono scarse evidenze scientifiche su efficacia"". Il Fatto Quotidiano (in Italian). 2020-0322. Retrieved 2020-03-23 . 23. A "AIFA precisa, uso favipiravir per CO VJD-19 non autorizzato in Europa e USA, scarse evidenze scientifiche sull'~fficacia ". aifa .gov . it (in Italian). Retrieved 2020-03-23 . 21. A NIH-000298 Gatherer D (August 2014) . "The 2014 Ebola virus disease outbreak in West Africa". The Journal o_/General Virology. 95 (Pt8) : 1619- 24. doi:10.1099/vir.0 .067199-0 . PMID 24795448. 25. A Oestereich L, Ludtke A, Wurr S, Rieger T, Muiioz-Fontela C, Gunther S (May 2014). "Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model". Antiviral Research. 105: 17-21. doi:10.1016/j.antiviral.2014.02.014. PMID 24583123. 26. A Smither SJ, Eastaugh LS, Steward JA, Nelson M, Lenk RP, Lever MS (April 2014) . "Post-exposure efficacy o_foral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model" . Antiviral Research. 104: 153- 55. doi:10.1016(j.antiviral.2014 .01.012 . PMID 24462697. 27. A "First French Ebola patient leaves hospital". Reuters. 4 October 2016. 28. A "Guinea : Clinical Trial for Potential Ebola Treatment Started in MSF Clinic in Guinea''. Al/Africa - All the Time. Retrieved 28 December 2014. 29. A Fink S (4 Februa,y 2015) . "Ebola Drug Aids Some in a Study in West Africa" . The New York Times. 30 . A Cohen J (26 February 2015). "Results from encouraging Ebola trial scrutinized". Science. doi:10. l l 26/science.aaa7912. Retrieved 21 Janua,y 2016. 31. A "Favipiravir in Patients with Ebola Virus Disease: Early Results of the JIKI trial in Guinea I CROI Conference". croiconjerence.org. Retrieved 2016-03-17 . 32. A Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, et al. (March 2016). "Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single -Arm Proofo_f'-Concept Trial in Guinea". PLOS Medicine . 13 (3): e1001967 . doi :10.1371/journal.pmed.1001967 . PMC 4773183 . PMID 26930627. 33. A "Japanese flu drug 'clearly effective ' in treating coronavirus, says China". The Guardian . 2020-03 -18. Retrieved 2020 -03-18. 34. A NHK World News 'China: Avigan effective in tackling coronavirus' 35. A Hu ax ia. "Fav ipiravi r shows good clin ical efficacy in treating COVI D- 19: officia l." Xinhuanet.com, 17 March 2020 36. A Cai, Qingxian; Yang, Minghui; Liu, Dongjing; Chen, Jun; Shu, Dan; Xia, Junxia; Liao, Xuejiao; Gu, Yuanbo; Cai, Qiue; Yang, Yang; Shen, Chenguang (2020-03-18). "Experimental Treatment with Favipiravirfor COVID-19 : An Open-Label Control Study" . Engineering . doi: 10.1016/j .eng.2020.03 .007. ISSN 2095 -8099. 37. A Dong, L; Hu , S; Gao, J (2020). "Discovering drugs to treat coronavirus disease 2019 (COVJD-19)". Drug Discoveries & Therapeutics. 14 (]): 58-60. doi:10.5582/ddt.2020.01012. PMID 32147628. 24. A show • V • t • e RNA virus antivirals (primarily JOS, also SOIAD and D06BB) Hepatitis C NS3/ 4A • Asunaprevir NIH-000299 protea se inhibitors (pre vir) • Bocep revi.-i • Cilu previr§ • Danoprevirt NSSA inhibitor s (asvir) • • • • • • • Faldaprevirt Glecaprevi r Grazop revir Narla previr Parita previr Simeprevir Sovaprevir t • • • • Telaprevirt Vaniprev ir Vedroprev ir§ Voxilaprevir • • • • • • • Daclatasvir# Elbasvir Ledipasvir Odalasvir t Omb itasvir Pibrentasvi r Rav idasvi rt • Ruzasvirt • Samatasv irt • Velpatasvir • Beclabuvirt • D asabuvir# • De leobuvi r§ N SSBRN A polymeras e inhibitor s (buvir) • Fi libuvir§ • GS-662 0§ • Setrobuvir§ • Sofosbuvir# • Radalbuv ir t Combination drugs • • • • Upr ifosbuvirt Elbasvir/grazoprevir Glecaprevir /pibrentasv ir Ledipasv ir/sofos buvir# • Omb itasvir/paritaprevir /ritonavir# • Sofosbuv ir/daclatasv ir • Sofosbuv ir/velpatasvi~ • Sofosbuvir/velpatasvi r/voxilaprev ir Pico ma viru s • viral enhy:P lecona rilt Anti-influ enza • Baloxavir marboxil NIH-000300 agents • Pimodivir t • Umifenovi r • adamantane derivatives /M2 inhibitors (Adapromine • Amantadine • Rimantadine) • neuraminidase inhibitors/release phase (Ose ltamivir# • Zanamivir • Peramivir, Laninamivirt) • Interfero n alfa 2b • Peginterferon alfa-2a# Interferon • Peginterferon alfa-2b# • EICAR§ • Fav ipiravir • Galidesivir t • Remdesivirt Multiple/genera I Multiple/unknow n • • • • • • Mericitabine t MK-608§ NITD008§ Moroxydine Presatovir t RibaviriI,# • Taribavirin t • Triazavirin • #WHO-EM • !Withdrawn from market • Clinical trials: o tPhase III o §Never to phase III show • V • t • e Filoviridae • Bundibugyo ebolavirus o BDBV Ebola virus Species • Reston ebolavirus o RES TV NIH-000301 • Sudan ebolavirus o SUDV • Tai' For est ebolavirus o TAFV • Zair e ebolavirus o EBOV • 1976 Sudan outbreak • 1976 Zai re outbreak • 2013-2016 West African Ebola virus epidemic o o o o o o o o o o o o o o o Outbreaks Dru g candidates • • • • • • • • • • • • • • • • • Timeline Reported cases and deaths Responses United Nations Ebola Response Fund Operation United Assistance in Guinea in Liberia in Mal i in Nigeria in Sierra Leone in Spain in the US in the UK Ouse to Ouse Tock Womey massacre 2014 DR Congo outbreak 2017 DR Congo outbreak 2018 Equateur, DR Congo outbreak Kivu Ebola epidemic BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAbl 14 TKM -Ebo la(failed) Triazavirin ZMapp NIH-000302 • Vaccines • • • • o cAd3-ZEBOV o rVSV -ZEBOV William Close Jean-Jacq ues Muyemb e-Tamfum Peter Piot Selected patients o Ameyo Adadevob Notable people Popular culture Miscellaneous • • • • • • • • o Kent Brantly o Pauline Cafferkey o Thomas Eric Duncan o Salome Karwa h o Sheik Umar Khan o Matthew Luk:wiya o Mayinga N'Seka o Patrick Sawyer The Hot Zone(l 995 book by Richar d Preston) Outbreak(1995 film) Ebola Syndrome(l 996 film) Executive Orders(l996 novel) 93 Days(2016 film) Ebola virus disease Ebola vims disease treatment research Ebola River • Marburg marburgvirus Species Outbreaks 1lf arburgvirus Drug candidates Popular culture Miscellaneous • • • • • o MARV o RAVV 1967 Marburg virus outbreak in West Germany 2017 Uganda Marburg virus outbreak BCX4430 FGI-103 FGI-106 • The Hot Zone(l995 book) • Marbur g virus disease • Marbur g Cueva virus Species • Lloviu cuevavirus (LLOV) Di ------~~ (b)( > (b_H_. ; Beigel, John (NIH) [E) Cc: Eleanor Fish (b)(6b Subject: IFN treatmen t for COVID-19 Dear Ors. Fauci and Seigel Regards, Howard NIH-000307 ----------------~= (b)(6)> From: Eleanor Fish Date: Saturday , March 21, 20 20 5 :25 PM To: Young, Howard (NIH/NCI) [E]________ Subje ct: IFN treatment for COVID-19 (b_H_6l Dear Howard, I wanted to share with your our findings from a clinical study Please keep this confidential. The manuscript has been submitted fo r consideration for publication . Eleanor N. Fish, PhD, FAAS UHN Emerita Professor & Associate Chair International Initiatives & Collaborations Dept . Immunology, University of Toronto NIH-000308 (b) (4) Fauci, Anthony (NIH/NIAID) [El Mon, 23 Mar 2020 13:40:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: From: Date: To: Subject: Please handle. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (30 496"'4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the orig inal intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . -------------- From: Schur , Peter H.,M.D. Date: Monday, March 23, 2020 9:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: (b)(6)> -------- --=-= (b)(6) Dear Dr Fauci I am look ing for help and informagtion. I am still wo rking fu lltime at Brigham and Women's Hospit al (BWH) as a Rheumatologist-although with the pandemic I am currently working from home I am also the Medical Director of the BWH Clinical Immunology Lab. We are looking for a company that can provide us with kits to assess lgG and lgM antibodies t o COVID-19. Can you, or one of your staff help us find those companies When I was at WRAIR many years ago (b)(6) they had a walk in -70C freezer with (b) (4) NIH-000313 (b) (4) Thank you for your help. Applaud what you are doing on TV. Applaud what you are doing for this pandemic Trust you are well Peter H Schur MD Senior Physician Brighasm and Women's Hospital Professor of Medicine Harvard Medical School Boston MA Tel: 617-732-5350 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information , please contact the Partners Compliance HelpLine at http://www.partners.org /complianceline . If the e-mail was sent to you in error but does not contain patient information , please contact the sender and properly dispose of the e-mail. NIH-0003 14 From: Date: To: Subject: Att achment s: Fauci, Anthony (NIH/N IA ID) [E) Mo n, 23 M ar 2020 13:02:15 +0000 Stephen Hahn FW: Quick Review: Press Confe rence Open - March 23 Press Confer e nce Open - M arch 23 - with Fauci edits .do cx Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (3 96':44li9 E-mail: Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the orig inal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-0003 15 NIH-0003 16 From: Date: (b)(6) Mo n, 16 Mar 2020 14:53:22 -0400 To: Adams, Jerome (HHS/OASH);Brett Giroir Subject: Fwd: Revised social distancing documents - word and powerpoint versions Attac hmen ts: US Social Distancing Recommendations - CDC 1151am_ 3_16_2020 clean.docx, ATT00001.htm, US Social Distancing Recommendations - CDC 1151am_ 3_ 16_2020 track changes.docx , ATT00002.htm, Social Distancing vs 316 2020.pptx, ATT00003.htm FYI Begin forwarded me ssage: From: "Schucha t, Anne MD (CDC/OD)" (b)(6) Date: March 16, 2020 at 12:04: 14 PM EDT To: "Birx, Deborah L. EOP/NSC" (bH6J > , "Azar , Alex OS/IO~ " (b) < , "Giroir, Brett (HHS/OASH) " (bH6) , "Harrison, Brian (HH S/1OS)" (b)(6) "Fauci , Anthony (NIH/NIAID) [E]' (b)(6) "Kadlec , Rob ert (OS/ASPR/ 10)" (b)(6) -----::-::-:-= Cc: "Redfield, Robert R. (CDC/OD)" _____ , "McGowan, Robert (Kyle) (CDC/OD/OCS)" (b)( >, "Schucha t, Anne MD (CDC/OD)" ______ (b_H _6), "Green , Hugh (CDC /OD/OCS )" (b)( >, "Hoo, Elizabeth (CD C/OD/OCS)" (b)(6) Subject: Revised social distancin g docum ents - word and powerpoint versions ---------- == --------- On behalf of Dr Redfield, I am forwarding a revised word document (clean and track changes) and a revised powerpoint w ith two slides. These drafts incorporate feedback that Dr Redfield received from the WHTF as well as the emE.Lein e...a. vide.oce..::bas e..Jh us W.E!... bavP...,. com b ined o[i.oc_adv icP...,. oo vp_c;t e_r_dav.'.,_ c;ver,sinn_th a_~ (b) (5) Anne Schuchat, MD Principal Deputy Director Centers for Disease Control and Prevention Rear Adm iral, US Public Health Service (Retired) NIH-000484 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 202012:37:15 +0000 To: Howard Bauchner;Butler, Jay C. (CDC/DDID/OD);Preeti Malani;Eli Perencevich;Phil Fontanarosa Cc: Edward Livingston Subject: RE:Testing - JAMA - Important Howard/Jay: I liked Jay's answers to Howard's questions even though there were still some open issues. will have to leave it to Jay and the CDC to continue with the discussion since I am really swamped. Sorry. Thanks, Tony From: Howard Bauchner Date: Saturday, March 14, 2020 7:48 AM ---- :::-c-r,-= To: Butler, Jay C. (CDC/0010/00) (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6l; Preeti Malani ; Eli Perencevich ; Phil Fontanarosa Cc: Edward Livingston Subject: Re: Test ing - JAMA- Important -------- Thanks Jay Have also copied Ed - This is crossing my desk 4-5 times per day now - and will only get more important (and sadly confusing) - in the weeks to come. Some questions would focus on public others on HCW (where I am sure general guide; talk with your CMO). I do love the mention of monopo ly - ------------- What you t hink? HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of th is email NIH-000634 (b)(6) listen to my chats with authors (b)(6)> From: "Butler, Jay C. (CDC/DDID/OO)" Date: Saturday, March 14, 2020 at 6:42 AM To: Howard Bauchner , Tony Fauci 6b , Preeti Malan i , Eli Perencevich , Phil Fontanarosa Subject: Re: Testing - JAMA - Important ------- --------- [Warning External Email] Good morning, Howard-some answers and non -answers. As is the case for most answers, the most accurate is "it depends", but I realize that is not helpful in busy clinical settings: No symptoms - get test posit ive - can you work At this point in the pandemic, no. While we do not know what role asymptomatic infection may play in transmission and it is plausible that someone who is NOT coughing and sneezing (or any other respiratory droplet self-generating acts)is going to be less infectious than someone who is, persons known to be infected should self-isolate. This, of course, is particularly important for someone who has closed contact with someone at greater risk of severe illness and health care providers . Symptoms - test negative - can you work- or do you need 2 negatives - or the test has to be done 2-3-4 days after you develop symptoms Even before COVID-19, working while ill with a respiratory illness puts others at risk. Particularly during when flu activity is high. Not toughing it out and going into work wh ile sick is more important now than ever and is an important component of social distancing-this is one of the founda tional ways that we distribute the impact of the pandemic over as long of a period as possible. (We are all gett ing good a drawing the two pandemic curves in the air on imaginary xand y-axes.). One of the critical areas where we need more data is on when someone who is infected becomes test -positive. Presumably, test-positivity would correla te wi t h viral load in the respiratory tract and a + would indicate greater likelihood of infectiousness. But the real challenge of the return-to-work issue lies in your next question: Test posit ive - back to work when -do you need negative tests- or just time - ? 2 weeks after first symptoms, first test positive. Ah, there is the rub-currently, the recommendations vary-CDC has gone with 2 negative swabs 24 hours apart, but we do not believe that positivity during recovery necessarily proves infectiousness. This is a crucial question. We are reviewing the available data, examining at how PCRpositivity, cycle threshold, and v iral culture line up - the goal is to develop good, NIH-000635 clinical parameters to justify ending precautions, rather than requiring microbiological tests. A Get Out of Isolation Free card, if you will. The hypothesis we are testing to 2 weeks after onset and >72 hours without symptoms. Currently the published recommendations are not satisfying: https ://www.cdc .gov/co ronav i rus/2019 -nCoV/ la b/guid eli nes-cli nica 1-speci mens.htm I I may have more information on this topic later today. Finally, in all complex epidemics, there is a tendency to search for a silver bullet-that one thing that will solve all of our problems. When an intervention is in short supply, the bullet turns platinum-"if only we could do x, the problem would be solved". This was vaccine in 2009 HlNl, naloxone in the opioid crisis, and now testing in coronavirus. Increased access to testing is desperately needed to control the COVID-19 pandemic. However, it is going to take a scientifically and wholistic and systemic approach to mitigate the impact. You have nicely outlined some of the "next questions" that are raised when testing is more widely available. More to follow. Best regards, Jay Get Outl ook fo r iOS From: Howard Bauchner Date: Saturday, March 14, 2020 5:53 AM To: Butler, Jay C. (CDC/DDID/OD); Fauci, Anthony (NIH/NIAID) [E]; Preeti Malani; Eli Perencevich; Phil Fontanarosa Subject: Testing - JAMA - Important Jay/Tony Some very complicated questions around testing have come up and w ill only increase. No symptoms - get test positive - can you work Symptoms - test negative - can you work - or do you need 2 negatives - or the test has to be done 2-34 days after you develop symptoms Test positive - back to work when - do you need negat ive tests - or just time - ? 2 weeks after f irst symptoms, first test positive . As tests become more w idely available this wi ll be devil folks. NIH-000636 Any ideas who can write about this. Jay - does CDChave specific recommendations. Sorry to bother on Saturday morning -but would like to get up a VP as soon as Tuesday. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Network Please respect the confidentiality of this email Listen to my chats with authors NIH-000637 Fauci, Anthony (NIH/NIAID) [El Sun, 22 Mar 2020 23:06:12 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Antibody Tests and Follow-on Use of 'Survivors' From: Date: To: Subject: ----------- From: Estes, Franklin J {Frank) LTC USARMY335 SIG CMD {USA) Se nt : Sunday, March 22, 2020 12:30 AM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Subject: Antibody Tests and Follow-on Use of 'Survivors' ------~= (b)(6) Dr. Fauci, I apologize in advance for bugging you but please read and pass along to the appropriate person, if useful. In the coming weeks, an antibody test for COVID-19 should be available (I suspect) . As 'survivors' are identified in the general population and are determined to be largely 'immune ' to COVID-19, I think those people should be given the opportunity to administer testing to others in the general population. The employment of VOLUNTEERsurvivors in the administ ration of tests would allow immune individuals to quickly learn how to collect samples and deal w ith potential infected patients face-to-face without fear of j eopardizing their own health or the health of the communities in which they live. This would free up highly trained nurses and doctors from testing and have an exponential benefit as survivors adm inister tests for infection and tests for antibodies and, thus, identify additional survivors. This would support more aggressive testing to bring about the eventual end of this virus when we try to identify every last infected individual who needs to be quarantined . Note: I understand we haven't yet determined whether survivors can be re-infected. So early volunteers may be subjected to further sickness. But the rate of re-in fectio n should be less as a percentage than the rate of infection among the general population. And re-infection would likely be less severe. Note2: Creating a VOLUNTARY REIGSTRYof survivors (those wi th suffi cient antibodies) may have a secondary benefit to businesses. It would allow businesses to quickly hire employees who could come in contact with the general public (thinking of current food delivery, grocery stores, daycare ...and later ...teachers, anyone in the medical or dental field, other retail businesses). I do understand my recommendations would generate HIPAA concerns but these are extraordinary times which call for out-of-the-box ideas...and this would all be voluntary. Thank you for taking a couple of minutes to read this and thank you for managing a very diffic ult crisis. You and others on your team have saved a lot of lives and we are eternally grateful. Respectfully, Frank Estes (b)(6) ----- (cell) NIH-000333 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 11:17:11 +0000 --------------RE: (b)( USARMEDCOM (USA) Recommendation (b)(6) Thank you for your note. Best regards, Tony From: Date: Tuesday, March 17, 2020 6:52 AM To: Fauci, Anthony(NIH/NIAID) [E] Subject: Recommendation (b)(6) ----------- USARMEDCOM (USA) ------~~ (b)(6 )> (b)(6) Dr. Fauci, I am a Nurse Practitioner (b)(6) for the US Army . I have a recommendation as we move through this terrible time in the US as well as the world. To preserve the healthcare workforce why not give 25% of all health workers in the military the trial vaccine? Keep these workers away from patients until which time that t he body can build immun ity . Let 's not expose the entire medical workforce to the COVID-19. The idea is that this 25% can take care of the population (post-vaccine) without worry of getting ill and causing further spread of the disease. If there is possibility of the vaccine, trial age cohorts and demographics could play a crucial part in testing . Thank you for all you are doing to protect the health of our Nation. Respectfully, (b)(6) NIH-000454 From: Date: To: Cc: [E]; ---------~~ ----------- Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 23:47 :21 +0000 Hahn,S tephen Redfield, Robert R. (CDC/0D);Birx, Deborah L. EOP/NSC;Lane,Cliff (NIH/NIAID } (b)( ·Rom, Colin (FDA/OC) RE:Treatment Document Sounds good to me. Thanks, Tony From: Hahn, Stephen (b)( Date: Friday, March 20, 2020 7:36 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Redfield, Robert R. (CDC/OD) > ------~~ (b)(6) (b)(6) Birx, Deborah L. EOP/NSC >; Lane, Cliff (NIH/NIAID) [E) ============~ ..:-.:.::::=====~~ Cb _H_6); Rom, Colin (FDA/OC)_______ _ (b)( __________ Subject: Re: Treatment Document Tony, Looks like (b)(S). The group wants to make some more edits and then send out this evening for review . We would like to meet up prio r to or after the task force meeting tomorrow. Sound OK? Steve Sent from my iPad On Mar 20, 2020, at 7:06 PM, Hahn, Stephen _____ Cb _> _<_.> wrote : I have a couple of comments (b)(S) I'll await for other comments. Thanks Steve Sent from my iPad NIH-000375 On Mar 20, 2020, at 6:45 PM, Fauci, Anthony (NIH/NIAID) [E] (b)(6)> wrote: -------- Team : As per my discussion with Steve a few minutes ago, I have made some changes in the document. ------------------------attaching a tracked version of the document (b)(5) (b)(5J I am that was your FINAL as well as a clean copy with all of the changes accepted. Please take a look and Steve said that he would like to set up a quick call to discuss after you have had a look . I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document Than ks, Tony as I was in a car. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confiden tial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. <> NIH-000376 To: Fauci,Anthony (NIH/NIAIO)[E) Mon, 23 Mar 2020 12:58:59 +0000 Barasch, Kimberly (NIH/NIAID) [Cl Subject: FW: Respiratory Protection Program: Temporary Suspension of Fit Testing From: Date: For my cli nical center Certifi cat ion f older. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ------[El-------=-=--== -------- From: Wu, Sarah(NIH/OD/ORS)[El Date: Monday, March 23, 2020 8:56 AM (b)(6) To: Fauci, Anthony (NIH/NIAID) (b)((;)> Subject: Respiratory Protection Program : Temporary Suspension of Fit Testing RespiratoryProtection ProgramParticipants: Due to the recent COVID-19 outbreak and supply chain shortage, we are temporarily suspending annua l fit tests for emp loyees at th is time. You w ill still be required to comp lete fit testing if: • you have experienced significant physical changes likely t o impact the fit of your respirator such as: o substantial weight loss/gain o dental surgery o cosmetic surgery including the neck area and above o an accident o a new medical diagnosis • you are direct ly invo lved in the COVID-19 response and are expected to be in close contact with potentia l COVID-19 patients • you are emergency response personnel (police, fire department, etc.) required to be onsite throughout this pandemic NIH-0003 17 If you do not meet these criteria, you are not required to complete your fit test at this time. Please be advised that you will still need to complete the online training despite the suspension of fit testing. Regular fit testing will resume once the COV/0-19 emergency has subsided. Any questions concerning the Health Rx website should be directed toward support@healthrx.com . Please visit the manufacturer's webs ites for details on your particular respirator model. If you have questions about N95 respirators in general, feel free to email nihresp irator@ma il.nih.gov. Thank you for your efforts and consideration during this event. NIH-000318 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:58:16 +0000 Karen Backman RE:Your Unprecedented Leadership and Professionalism Kare n: Many thanks for yo ur kind note . Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Karen Backman (b)(6) Date: Monday, March 23, 2020 8:53 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subj ect : Your Unprecedented Leadership and Professionalism ------ --.~ Good morning Dr. Fausi, I am not one to write emai ls to our leaders in government as I am sure that the message doesn't get to where it always needs to go . At the risk of you possibly seeing this email, you need to know that you are doing an incredible job . I doubt you will be broadcasting th is note but you should know that my husband and I take great comfort in seeing you up on the podium next to our country's leadership on the COVID-19 pandemic. You are a steady voice of reason and the right person for the job. Even when the President doesn't get it quite right , you manage to be professional in your delivery, information and steadfast manner. We can easily look past the President but we listen when you speak. From the first time I heard you say on a Sunday morning talk show, "If you th ink we are overacting then we are probably doing the right things ." I live in Maine and we are a rural state so we probably won't see the numbers that are elsewhere but we are listening and acting on you r words of caution. NIH-000319 I can't imagine how much pressure you are under doing your job but we need more leadership such as yours . How you choose your words so carefully without getting flustered is a gift . I can on ly hope that you will continue to be the voice to get this country through this unprecedented event. Stay healthy and keep doing what you're doing as it matters so much to this nation. Sincerely, Karen L. Backman NIH-000320 From: Date: To: Subj ect : At tac hment s: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 12:46:08 +0000 (b)(6) Confidential Press Conference Open - March 23 - with Fauci edits .docx Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00032 1 From: Fauci,Anthony (NIH/NIAIO)[E) Date: To: Subject: Mon, 23 Mar 2020 12:25:31 +0000 info@mail.mlblists.com RE: Fill the baseball void: Trivia, A-Rod clinic, classic games My work with t he Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each individual message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.O. Anthony s. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)(6) FAX: (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000322 From: Date: (b)(6) Mo n, 23 Mar 2020 07:32:09 -0400 To: Subject: Attachments : DMID Word Nerds Fwd: COVID-19- NOVELDRUG _________ (b_H _. 4) 3_17_2020.pdf, ATT000Ol.htm Sent from my iPhone Begin forwa rded message: From: Radka Milanova (b)(6) Date: March 23, 2020 at 1 :43:46 AM ED T To: "Fauci, An thony (NIH/NlAI D ) [E]" --------=-=--:= (b)(6>f --------Subject: COVID-19-NOVELDRUG Dear Dr. Antho ny Fauci: (b)(4) (b) (4) NIH-000323 (b) (4) I lo ok forward to hearing from you . Kind regards, Radk11Milanova , PhD. Office: + 604 488 8880 Mobile· (b) (6) Email: milanova@,sliaw.ca This message and any aua chme111sare i11te11ded011/y for the use of the addressee and may contain information that ls privileged and confidential. If the reader of the message is nm the intended recip ient or an authorized representative of the intended recipient, you are hereby notified that My dissemination of this comm 1micotio11 is s trictly prohibited. If you have received this communicatio n in error . please notify us immediately by e-mail and delete the message and any a/tachmentsji·o m your system. NIH-000324 Fauci, Anthony (NIH/NIAID) [E] Mon, 23 Mar 2020 01:37:39 +0000 To: David Rubenstein Subjec t: FW: USAToday/David M . Rubenstein-- Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need From: Se nt: David: You were so very kind to me in this article . Thank you so much. Warm regards, Tony Coronavirus hero: Anthony Fauci is a great public servant in a time of great public need Fauci is the wo rld's leading authority on infectious diseases and the best person in the country to help us deal with the COVID-19 crisis. David M. Rubenstein Opinion contributor Some viewers of the daily White House coronavirus briefings may wonder why everyone increasingly defers to a diminut ive, Brooklyn -accented 79-year-old doctor, Tony Fauci. They do because, as I have learned over many years of talking with and more recent ly interviewing this man, he is without doubt the world's leading authority on infectious diseases. In any area of human activity or knowledge, there always seems to be one person who is the global gold standard. In the world of infectious diseases that person is Tony Fauci. So the American people - indeed, people around the globe - should be grateful that Tony has dug into this crisis with the same work-around -the-clock, just-the -facts ma'am style that he has used while serving under and working with six U.S. presidents . He is as apolitical as anyone can be. I have no idea if he is registered with any politica l party; I suspect though that he is rabidly Independent. His only focus is getting the facts out, providing the best health care treatment and information possible, and saving lives. A top exper t from AIDS to Ebola Tony Fauci joined the National Institutes of Health in 1968, after completing his medical training at Weill Cornell Medical Center, and he has led the National Institute of Allergy and Infectious Disease since 1984 - 36 years. Hard to believe anyone can run anything that long and still be at the top of his game. But Tony is. During this period , he has dealt with every serious infectious disease challenge - malaria, Among Tony's best known accomplishments, beyond simply running the institute and training dozens of the world's top infectious disease professionals, has been helping to discover how HIV leads to AIDS and, later, leading the effort to create (at President George W. Bush's direction) the President's Emergency Plan for AIDS Relief (PEPFAR),which has transformed the treatment of HIV/AIDS in Africa, and other parts of the developing world. Millions of lives have been saved by this program alone. More recently, he has been an architect and powerful advocate of President Donald Trump's plan for ending the AIDS epidemic in the U.S. through HIV antiretroviral therapy targeted to disease hotspots. NIH-000325 In his spare time, Tony has been involved with writing or editing more than 1,100 scholarly articles and several textbooks, and, in the process, has become one of the most cited authorities of the entire medical profession. For these breakthrough activities and his dedicated service (at a government salary) for more than a half century (he worked at NIH for 16 years before assuming his current role), Tony has received, and earned, the Presidential Medal of Freedom and a Lasker Awa rd (called the Amer ican Nobel by many). With this long service and universal acclaim, one might think Tony would let it get to his head, at least a little bit. Not the case, though. Selfless commitment to public service He is read ily accessible to those who need treatment - he still runs a lab at NIH - or need information. Tony still lives in the same house he bought when he first moved to Washington, and it is there that he and his wi fe Christine have raised their three talented daughters (though none of them chose to attend medical school) . Until the latest crisis, Tony has often commuted to NIH by Metro, typically after running t hree miles for his daily exercise. And when he has been invited to make speeches in the Washington area or on Capitol Hill, he invariably turns down a car and driver fo r the Metro. (This practice has had to change of late for the obvious reasons). There are, of course, many other dedicated federal servants who also view their commitment to the country and its people over financial rewards . But surely no federal civil servant, in any area, can exceed Tony Fauci's long-term and selfless commitment to this count ry and the health of its people . I tried years ago, when Tony was approaching a normal retirement age, to see if he might want after a normal lifetime of federal service, to take some of his considerable skills and knowledge to the private sector. He quickly said no - money did not mot ivate him, serving the country did. And he stayed at NIH - to the country's good fortune. If there is any one medical professional who can help the country deal with the COVID-19crisis, it is Tony Fauci, an example of the best this country has to offer. He is not a miracle worker. No one is. But Tony Fauci has the decades of experience needed to understand infectious disease problems and prescribe a trea t ment that should, in time, provide the requisite comfort, even if, in the short term, the medicine is painful and inconvenient . David M. Rubenstein is the co-executive chairman of The Carlyle Group. Disclaimer: Any third-party material in this email bas been sbarcd for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAJD, NIH , HHS, or the U.S. government. NIH-000326 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Mon, 23 Mar 2020 01:23:55 +0000 Marston, Hilary (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E]; FW: Possible agenda for Wednesday COVID-19 TransNIH_032520 hm.docx ----- ------- -=-a=, (b)(6) Please take the lead in putting together slides for Wednesday . If I can make it (which is uncertain),! will need them to make a presentation . Thanks,\Tony From: Marston, Hilary (NIH/N IAID) (E] (b)(6) Sen t : Sunday, March 22, 2020 7:10 PM To: Collins, Francis (NIH/OD) [E] -----~~ (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E) (b)(6) Wolinetz, Carrie (NIH/OD) [E) (b)(6); Anderson, James (NIH/OD) [E) (b)( >; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Lane, Cliff (NIH/NIAID) [E) (b)(6)> Subject: Re: Possible agenda for Wednesday -:--.-----:-:-:-:-:;::===::.:....---=-c~ Thanks for the chance to weigh in. I have it blocked on my calendar and would look forward to the discussion. And I'm happy to pull slides together as outlined. Here are some minor comments on the agenda, which looks excellent. Looking forward to it, Hilary From: "Collins, Franc is (NI H/OD} [E]" Date: Sunday, March 22, 2020 at 5:09 PM To: Hilary Marston (b)(6) (b)(6)> Cc: "Tabak, Lawrence (NIH/OD} [E]" (b)(6)>, "Wolinetz, CbH >, "Anderson, James (NIH/OD} [ E]" "".-~-~---:~===:...:....---,;-, = Anthony Fauci CbH6)>, Henry Lane (b)(6) Subj e ct: Possib le agenda for Wednesday Carrie (NIH/OD) [E)" CbH6), Hi Hilary, I've been through the COVID-19 ideas collected from your Deputies meeting, plus reaching out for a few other inpu ts. What I hope to do is to assemble this into a lively three-hour discussion on Wednesday afternoon (2 - S PM). Tony is enthusiast ic about our doing this, but his presence is unfortunately doubtful, given all of the other demands he faces. I'm counting on you and Cliff to be there, however is this etched on your calendars? NIH-000327 Pleasesee attached for my rather rough first attempt at an agenda. It's a lot of topics and the list will probably need to be culled- ...,_________....,.___________ ___________ (b)(5) - I wou ld want there to be time for discussion in each theme, so that other ideas could be floated. Please let me know your thoughts, ideally this evening. I'm also asking for input from others who are cc'd here. Best, Francis NIH-000328 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [E) Mo n, 23 Mar 2020 00:56:30 +0000 Jon LaPook RE:Tony , my three minut e shp iel on CBSSunday Morning today . Very well done as usua l. -----Original M essage ----From: Jo n LaPook ,.....___ _,(""' b),,.., (6) => Date: Sunday, March 22, 2020 8:25 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( Subject: Tony , my three minut e shp iel on CBS Sunday Morning today. ------ --;.-;~ Https ://www.c bsnews.co m/news/ corona v irus-covid- 19-socia I-distanc ing -how -to-reduce-risk-together/ Jon Jonathan LaPook, M.D. Chief Medical Corres pondent, CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000329 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Mon , 23 Mar 2020 00:51:49 +0000 McNeil Jr, Donald G Subject: RE: big story of mine just posted Donald : You not only got it right, but it was an extraordinarily comprehensive, informative and sobering article. I do not agree with everything that is being done by various countries, and you have indicated that many of these approaches are controversial. However, your repo rting of them is accurate and well-art iculated. Bottom line is that t his is an outstanding article. Best, Tony From: McNeil Jr, Donald G Date: Sunday, March 22, 2020 7:33 PM To: Fauci,Anthony (NIH/NIAID) [E)------= Subject: big story of mine just posted (b'"'"" )(=6) I would have interviewed you for it, but I know you're busy. I hope you think I got it right.. .. htt ps://www .nyt imes.com/2020/03/22/hea lth/coronavirus-rest rictions -us.ht ml Donald G. McNeil Jr. Science Correspondent illlJt ~t\u !Jork tEime11 Tel: +I 212 556 1142 mcneil @nytim es.com Artic les: https: //www.nyti.mes.com /by/dona ld-g-mcne il-jr NIH-000330 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 23:27:37 +0000 Murphy, Philip (NIH/NIAID) [El RE: Suggestion Phil: Thanks for the note. Very important point . Best, Tony --------7:23 ------~= [El -------- From: Murphy, Philip (NIH/NIAID) [El Date: Sunday, March 22, 2020 To: Fauci, Anthony (NIH/NIAID) Subject: Suggest ion (b)(6) PM CbH6)> All the best, ehil _______________________________ ~ NIH-00033 1 (b ~~~(S) (b) (5) Phil NIH-000332 From: Date: (b)(6) Sun, 22 Mar 2020 17:23:08 -0400 Cicala, Claudia (NIH/NIAID) [E] Re: Your idea about COVID-19 To: Subject: Thanks, Claudia On Mar 22, 2020, at 5: 17 PM, Cica la, Claudia (NIH/NIAID) [E] (b)(6) Dear Tony, Thank you for taking the time to answer. I want you to know that a huge number of people here and in It aly asked me to pass along a message of support. Thank you for all you are doing . Take a good care of yourse lf, Claudia Sent from my iPhone On Mar 22, 2020 , at 1 :27 PM , Fauci , Anthony (NIH/NlAID) [E] (b) (6): Jim: (b) (5) I Needless to say, this is a overwhelmingly compelling pub lic health and scientific issue. Keep me posted. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000338 FAX: (301) 496-4409 E-mail: Cb ™ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000339 NIH-000344 NIH-000473 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAI0) [E) Sun, 22 Mar 2020 17:29:47 +0000 Hallett, Adrienne (NIH/OD) [E] RE: Senate Supplemental #3 Thanks ! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)> From: Hallett, Adrienne (NIH/OD) [El Date: Sunday, March 22, 2020 1:21 PM To: icddir-l@LIST.NIH.GOV Subject: Senate Supp lemen ta l #3 NAT IONAL INSTITUTES OF HEALTH NATIONAL HEART , LUNG, AND BLOOD INSTITUTE For an additional amount for ''N ational Heart, Lung, and Blood Institute'' , $ 103,400 ,000 , to remain available until September 30, 2024, to prevent, prepare for, and re- spond to coronavirus, domestically or intern ationall y: Pro- vided, That such amount is designate d by the Congress as being for an emergency requirement pur suant to sec- tion 251(b)(2)(A) (i) of the Balanc ed Budg et and Erner- gency Defici t Control Act of 1985. NAT IONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA SES For an additional amount for "N ational Institute of Allergy and Infe ctious Diseases", $706,000,000 , to re- main available unt il September 30, 2024, to prevent , pre- pare for, and respond to coronavirus, domes tically or internat ionally: NIH-000345 Provided, That not less than $156,000,000 of the amounts provided under this heading in this Act shall be provided for the study of, construction of, demolition of, renovation of, and acquisition of equip- ment for, vaccine and infectious diseases research facilities of or used by NIH, including the acquisition of real property: Provided further, That such amount is designated by 1. 2. 3. 4. 2 the Congress as being for an emergency requirement pur3 suant to section 251(b)(2)(A)(i) of the Balanced Budget 4 and Emergency Deficit Control Act of 1985. s. 5 NATIONAL INSTITUTE OF BIOMEDICAL 6. 6 IMAGING AND BIOENGINEERING 7. 7 For an additional amount for "National Institute of 8. 8 Biomedical Imaging and Bioengineering", $60,000,000, to 9. 9 remain available until September 30, 2024, to prevent, 10. 10 prepare for, and respond to corona virus, domestically or 11. 11 internationally: Provided, That such amount is designated 12. 12 by the Congress as being for an emergency requirement 13. 13 pursuant to section 25l(b)(2)(A)(i) of the Balanced Budg14. 14 et and Emergency Deficit Control Act of 1985. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 15 16 17 18 19 20 21 22 23 NATIONAL LIBRARY OF MEDICINE For an additional amount for "National Library of Medicine'', $10,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 25l(b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. HEN20279 S.L.C. 1. 2. 3. 4. s. 6. 7. 8. I 2 3 4 5 6 7 8 78 NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES For an additional amount for ' 'N ational Center for Advancing Translational Sciences" , $36,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus , domestically or internationally: Provided, That such amount is designated by the Congress as being for an emergency requirement NIH-000346 9 pursuant to section 251(b)(2)(A)(i) of the Balanced Budg10. 10 et and Emergency Deficit Control Act of 1985. 9. 11. 12. 13. 14. 15 . 16. 17 . 18. 19. 20. 21. 22. 11 12 13 14 15 16 17 18 19 20 21 OFFICE OF THE DIRECTOR For an additional amount for "Of fice of the Director", $30,000,000, to remain available until September 30, 2024, to prevent, prepare for, and respond to coronavirus, domestically or internationally: Provided, That these funds shall be available for the Common Fund established under section 402A( c)( 1) of the PHS Act: Provided further, That such amount is designated by the Congress as being for an emergency requirement pursuant to section 251 (b)(2)(A)(i) of the Balanced Budget and Emergency Deficit Control Act of 1985. NIH-000347 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 22 Mar 2020 17:28:59 +0000 To: Haskins, Melinda (NIH/NIAID) [E] Cc: Crawford, Chase (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Conrad, Patricia (NIH/NIAID) [E] Subject: RE: Dr. Fauci: Senate Draft COVID-19 Supp Date: (b)(5 Thanks. Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation. It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . From: Haskins, Melinda (NIH/NIAID) [E] Date: Sunday, March 22, 2020 1:24 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Crawford, Chase {NIH/NIAID) [E] (b)( 6) ---------- ------ == --------- (b)(6) (b)(6J> (b)(6)>; Selgrade, Sara {NIH/NIAID) [E] Subj ect : Dr. Fauci: Senate Draft COVID-19 Supp NIH-000348 (b)(6) From: Date: To: Subject: Sun, 22 Mar 2020 10:58:06 -0400 Miche la Carluccio Re: telmisartan and covid -19 Ms. Carluccio: Thank you for your note . Best regards , AS Fauci On Mar 22, 2020 , at 9:33 AM, Michela Carluccio (6)>wrote : (b) Dear Professor Fauci, sorry for the disturb. My name is Michela, I contacted her from Italy and I am (b)(6)years old. I hope you understand my concern, I will contact you for advice if possible: NIH-000349 (b)(6) (b)(6) Sincerely, NIH-000350 Ms. Michela Carluccio NIH-000351 To: Fauci, Anthony (NIH/NIAID) [E] Sun, 22 Mar 2020 05:29:11 +0000 guy@vidaldesigncollaborative.com Subject: RE:• Suggestion from former Israel Defense Forces member From: Date: My work with the Coronavirus Task Force and the large volume of incoming emails precludes me or my staff from answering each indiv idua l message. I would encourage you to visit www.coronavirus .gov for the latest information and guidance related to COVID-19. Thank you, and best regards. Anthony S. Fauci, M.D. NIH-000352 From: Date: To: Cc: Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 21 Mar 2020 23 :02:34 +0000 Redfield, Robert R. (CDC/OD) Conrad, Patricia (NIH/NIAID) [E] TF Agenda for tomorrow (Sunday) White House Coronavirus Task Force Agenda 3.22.20.docx Bob: See attached TF Agenda for tomorrow. ----------------Tony (b) (5) (b)( S) (b)(S •. Many thanks, Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX:(301) 496-4409 E-maill (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000353 From: (b)(6) Date: Sat, 21 Mar 2020 18:17:02 -0400 A uchincloss, Hugh (NIH/NIAID) [E] Folkers, Greg (NIH/NIAID) [E] Fwd : Posit ive COVID-19 test result for To: Cc: Subject: ---------- (b)( Sent from my iPhone Begin forwarded message: (b)(6) > From: "Holland, Steven (NIH/N IA]D ) [E]" Date: March 2 1, 2020 at 4:40 :28 PM EDT To: "McGowan , Colleen (NIH/OD /ORS) [E]" CbH6) >, "Fauci, An thony (NIH/N IAID) [E]" CbH >, "Lane , Cliff (NIH/N IAID) [E]" _____ Cb _>< _ , "Harper, Jill (NIH/N IAID ) [E]" CbH6J >, "McGowan , John J. (NlH/NIA ID) [E]" ----- (b)(6) (b)(6) Subject: Re: Positiv e COVID-19 test result for Thank s, Colleen. the loop. I am also know Iedge . -------------- Steve Director, Division of Intramural Research National Institute of Allergy and Infectious Diseases Nationa l Institute s of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistant lab: Eva Porti llo (b)( email (b) (6) voice ===~-.::---- ----- NIH-000354 ------------ (b)(6) Cb)(6), to bring him into Cb)(6) into this for her Assistant to SD: Beth Schmidt (b)(6) ----- (b)( voice From: "McGowan, Colleen (NIH/OD/ORS) [E]" Date: Saturday, March 21, 2020 at 4:17 PM To: Steven Holland (b)( Lane ========~Henry John J McGowan (b)(6) --------- CbH6)> >, Anthony Fauci CbH >, Jill Harper (b)(6), CbH6)> Subject: Positive COVID-19 test result for (b)(6) I'm writing to share that we have received a positive COVID-19 test result of (b)(6) These results just came out of the 2pm test run today. supervisor CbH6J The person reported being symptomatic on 3/13/2020, contacted OMS on Monday, but d idn't get scheduled for testing till Friday 3/20/20. I'm told (b)(6) continued to --- ir work (b)(6) even when feeling ill. I'm not permitted to share PHI, but I am to ld that OMS has notified the employee, and if they haven't done so already, OMS will contact the supervisor w ith general information regarding the person's general health status. They will not divulge a positive test result for COVID-19, but rather state a general health condition which precludes the staff member from working. Since (b)(6) is working in ____________________ , I presume (b)(5) , but please let me (b)( know if this isn't the case. ORF typically closes down the location for 7 days to allow environmental dissipation of contact surface contamination. I know this area is mission critical, so I will help you contact ORF about prioritizing cleaning procedures. We ask that you take great care in keeping t hat information as confidentia l as you can. Thanks Colleen Colleen A. McGowan, MHA, FACHE Director, NIH Office of Research Services Bldg 31, Room 4B54 Office Phone: ___ "" (b)""'(=6) NIH-000355 NIH-000356 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 18:13:55 -0400 NIAID Public Inquiries Fw d: Jafri_Research Volunteering Sent from my iPhone Beg in forwa rded message: From: Riaz Jafr i (b)(6) > Dat e: March 21, 2020 at 5:34 :20 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Jafri_Re search Volunte ering --------- (b)(6J. Hi Dr. F auci, Hope you are doing well and thanks for your leadership during this pandemic situation. I have a medica l deg ree and has exper ience in bas ic and clinical resea rch for almost 30 yea rs . Currently in clinical trials, doing studies monitoring. I would like to voluntee r during this COVID-19 situations. Please let me know ifl can share in anyway. I appreciate it. Bes t regards and be safe .. Dr. Syed R . Jafr i Ph: (b)C6J Sent from my iPhone NIH-000357 From: Date: (b)(6) To: Sat, 21 Mar 2020 18:13:34 -0400 Cassetti,Cristina (NIH/NIAID) [E];Auchincloss,Hugh (NIH/NIAID)[E];Handley, Gray (NIH/NIAID)[El Subject: Fwd: Possible joint collaboration Polish -American Collaboration Hop ing one of you can handle. Taking this out of ASF inbox If we need to discuss with him let me know. Sent from my iPhone Begin forwarded message : From: Aleksandra W esolowska (b) (6) > Date: March 21, 2020 at 6:08:46 PM EDT -------~~ To: "Fauci, Anthony (NIH/NJAID ) [E]" (bH6J Subject: Possible joint collaboration Polish -American Co llaboration Dear Dr Anthony Fauci , I am w riting in connection to email from Prof Robert Schwartz about possible Polish - American collaboration in the clinica l trial focus on treatment patients suffer from COVID-19 As a Polish Medical Research Agency we desire fa cing th is pandemic with NIAID leading vaccine and therapy efforts against SARS-Cov-2. F. Gray Handley has got in contact with the President of our Agency last week but from that time we have no furthe r infor mation in this pressing issue. I will be very appreciated if we could discussed with you or your eminent staff any possibility for polish scientists to join t collaboration with NIAID to figh t corona vi rus for patients all of the world. I will be personally responsible to hold this topic on behalf of Polish Medical Research Agency. NIH-000358 Thank you for your time and incredible efforts you made to global health and safety. I remain at your disposal, AleksandraWesotowska,PhD Senior ResearchCoordinator Agencja Sadan Medycznych ul. Mo niuszki lA 00-014 Wars zawa www .abm. gov .pl NIH-000359 From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Sat, 21 Mar 2020 16:43:19 +0000 NIAIDODAM FW: Virtual Town Hall with College Students (30+ Schools)? From: John Monahan Date: Saturday, March 21, 2020 10:11 AM ------ --,;-,~ To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Virtual Town Hall with College Students (30+ Schools)? To ny-Fi rst of a ll, thank you for all you are doing to lead om country's respo nse duri ng this cr is is. I hesitate to reach out to you with so much on your plate , but I think this idea might help with the national response. In light of the con tinuing cha llenge of engaging young p eople in social dis tancing measures , combined with the fact that so many colleges and univer sities are now teaching online, Georgetown's Globa l Hea lth Initiati ve and Institute for Politics and Public Service are consideri ng a "vi11ual town hall" in which you could spea k directly with student s at co lleges and universitie s via Zoom (or some other platform) about the collective challenge of COVID-19 and its risk to their health and to other members of their communities. This could be a unique forum for you, as the most trusted per son in the public dialogue , to make the case directly to young people about thei r vital role in social distancing to flatten the curve in their communities. W/e would use social media, of course, to push out key segments and messages from this event more broadly. While Georgetown would organi ze this "virtua l town ha ll", we would work closely with a network of more than 30 colleges and universitie s with which our Institute of Politics and Public Service regularly collaborates. We would also reach out to other schoo ls to ensure a geograp hic reach and a mix of public and private institutions. Of course, our team wou ld work closely with your staff to manage all logistics so as to use your scarce time as efficiently as possible. Before we go any further in pl anning or thinking about this, I wanted to see if you would have time to participate or think this is a good idea. Be st! John John T. Monahan, JD NIH-000360 Senior Advisor to the President of Georgetown University Senior Fellow, McCowt School of Public Policy Senior Scholar, O'Neill Institute for National and Global Health Law Georgetown University 3307 M Street NW, Suite 202 Washington, DC 20057 202-431-6556 NIH-000361 From: Date: (b)(6) To: Subject: Sat, 21 Mar 2020 07:48:05 -0400 KENGLEN Re: COVID-19 Thank you for your note. AS Fauci Sent from my iPhone -------- On Mar 21, 2020, at 7;43 AM, KEN GLEN (b)( · wrote: Good morning, from Vancouver , Canada. We hope you are keeping yourself, and your families safe. Your calm approach, and real life experience being shared during the daily briefings is what everyone looking towards the USA for information needs to see. As in anything, real knowledge, both sharing and accepting is critical to get everyone focused on overcoming the current situation. We don't see social distancing between everyone at the news conferences, and that is disappointing, we also don't see Donald Trump acquiring the skills and abilities to truly turn over communication and leadership to people such as yourself and you r colleagues on the podium. Whi le that is also disappointing, it has come to be expected, therefore easy to tune out. Our Global world needs a Global approach of honesty and transparency, we can't afford to get this one wrong due to our normal tribal tendencies. Best regards, be safe, Ken &Cathy Glen --------- (b)(6) ) NIH-000362 From: (b)(6) Date: Sat, 21 Mar 2020 07:44:54 -0400 To: Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Provider's question! Subject: From Patty Can one of u pis take this. Sent from my iPhone Begin forwarded me ssage : From: "Ro stami , Nahid" Date: March 20, 2020 at 7:25 :06 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Cc: "Rostami, Nahid" (b)( Subject: Provider 's question! Dear Dr. Fauci, I am one of the UCSF neonatologist and I have been am (b)(6) now. As you know, in neonatal intensive care unit at least one parent stays at bedside. Considering the recent coronavirus outbreak, I am (b) (6)· for both potential patient (b) (6) and staff exposures. I appreciate your advice and recommendation for (b)(6) who is working in an inten sive care unit. Since I have to go to work , do I need to have extra percuss ions besides hand washing? If so, what would you recommend? I appreciate your help. Thanks, Nahid Rostami NIH-000363 From: (b)(6) Date: Sat, 21 Mar 2020 07:42:07 -0400 Parks, Donna (djholmes@uidaho.edu) Re:Thank you To: Subject: Thank you for your note. AS Fauci Sent from my iPhone > On Mar 20 , 2020 , at 8:49 PM, Parks , Don.na (djho lmes@uidaho .edu) wrote: > > Dear Dr.Fauci: > > I want to thank you and commend you for all you 're doing during the COVID -19 pandemic. You are the voice of science and reason - and you seem to be able to get through to President Trump in a subtle way yet with a grea t deal of integrity. I don't envy you this gig - part icu larly with an administration that is so hostile to science, reason, and preparedness on the federal level. > > I'm stil] squirming from Trump 's latest declara tions that hydroxquinolone could be used for COVID. The more you can explain why this might not be the place to put federal resource s right now , the better. Friends of mine are buying it off label in Mexico now, and as a biologist and medical educator I find this alarming. > > Thank s. You 're the best. > > Donna Holmes Parks I djholmes @uidaho.edu > WWAMI Medical Education Program > University of Idaho and University of Washington > > NIH-000364 From: Date: (b)(6) Sat, 21 Mar 2020 07 :39:16 -0400 To: Subject: Conrad, Patricia (NIH/NIAID) [E) Fwd: Coronavi rus interview Sent from my iPhone Begin forwarded m essage: From: "Lindenberger, Isaac D." <1indenberger.9@buckeyema il.osu.edu> Date: March 21, 2020 at 1: 19:57AM EDT To: "Fauci , Anthon y (NIH/NIAID) [E]" Subject: Coronaviru s interview ------- --== CbH6) Dr. Fauci, I have Pau l Offit coming on my podcast tomorrow to discuss coronavirus, and I would love to have you on after him to talk abo ut your tho ughts and what we should do. My friend Nikk i Roy recommended you who I have also interviewed for my vaccine show "Straight To The Point." If you 're interested we can do an interview at your earliest convenience. My listeners wou ld benefit grea tly from it, thank you for your cons ideration. Get Outlook for Andro id NIH-000365 From: Date: To: Subject: (b)(6) Sat, 21 Mar 2020 07:38:39 -0400 Friedmann, Theodore Re: COVID-19 information for the public Thank you for your note. AS Fauci Sent from my iPhone > On Mar 21 , 2020 , at 2:0 I AM, Friedmann , Theodo re wrote: > > Dear Tony: T'm sure that you realize how dism ayed and saddened many of us are at the inaccurate and harmful comments coming from our political leaders regarding the COVID-19pandemic. That feeling hit a new height today with the irresponsi ble and nonsensical announcement from President Trump regarding his claimed effectiveness of chloroquine and hydroxychloroqu ine. This announcement and many other untru ths were delusional, irrational, unscientific and revealed a profound ly harmful and unethical betrayal by President Tmmp his responsib ility to protect the health of the public that pus th republic in sever danger. I was very glad to hear your pub lic comments that countered this ho1Tibly danger ous misinfonnation. l hope that your message falls on receptive ears in the public and leads to a major change in the kind of public announcements that are currently being foisted on the desperat e pub lic who depend on knowing and acting based on the truth. Please continue and even expand your role as the truth teller in the who crowded collection of muzzled officia ls and sycophants who seem to be more devoted to deceiving the public rat her than preparing the public for hard truths and solving the logistics failures of masks, availability of testing its. Please continue your brave and essential role as honest broker that you play valiantly privately during your policy discussions that the public also deserves to know about the wrong and unethical self -serving propaganda that the public is fed by President Tnimp and some other members of the Corona Vims task force. It is a deadly governmental game. I wish you good luck in alerting the public to this imm oral, uneth ical and deadly plague of governmental misinformation designed to shape political quandaries rather than public welfare. Please continue speaking out about public misinformation. > > Ted Friedmann, MD > NIH-000366 From: Date: (b)(6) Sat, 21 Mar 2020 07:38:1 1 -0400 To: DMID Word Nerds Subject: Fwd: hypertensive drug - ACE2- inhb itor related and our w ork Attachments : A Combinatorial Antihypertensive Drug (Reserpine and Hydrazi ne) Does Not Cause Severe Depression .pdf, ATTOOOOl.htm,medrx ivcognitionandadelphanel.pdf, A TT00002.htm Sent from my iPhone Begin forwa rded message: From: "Dr.Jamuna R Subraman iam" Date: March 21, 2020 at 2:04: 14 AM EDT To: "Fauci, Anthony (NlH/NlAID ) [E]" (b)( ·,jamuna subramaniam (b) (6)> Subject: hypertensive drug- ACE2- inhbitor related and our work ---------,;-,= Dear Prof. Ant hony Fauci , Good Morn ing! I am Dr. Jam una R. Subramaniam. I did my Ph.D from Georgetown University and postdoc in Johns Hopkin s on neurodegenerative disease s. After r eturning to Indi a I started working on biogenic amine neuortransmitters. One of the major trajectory of my research career was on an FDA approved , antihyper tensive drug. Given the current scena rio of ACE2 being the receptor for Covid - 19, and the widely used antihype1tensive dru gs also targe t the same. I thought of sensitiz ing you on a very effect ive antihypertensive drug, adelphane and adelpha ne esidrex made and sold by Novaritis This contains a historical VMA T - biogenic amines loading in synaptic vesicles, molecule , reserpine. Here, in India, a well known Nephro logist, has used this to treat a commun ity of close to 3000 patients for almost two decades. From him and others I have heard that it is a very effective, well tolerated antihype rtensive. Res erpine is a historical molecule that it had been used in the Indi an syste m of medicine, Ayurv eda. But ade lphane has the single specific purified molecule , reserpine, an alkaloid. Now Nova ritis has stopped making it. One of the reasons being given is reserpine's nega tive publ icity when it was used an antipsycho tic drug. The reaso n given was a side effect of severe depression. We did a study on these patient s on adelphane and find that it had not caused depression . Fmther, it seems to be reta ining cognitio n in these patients. I could not pub lish these in big journals as you can understand. I am enclos ing these two papers. NIH-000367 As many lives are at stake, I thought I will sensitize you on this. Hope something good will come out of this . I am telling whomever I come across about the same. That is the best I can do. Hope the current scenario will show the living daylight for reserpine and helps the humanity. Thank you With regards Jamuna Dr. Jamun a R. Subramaniam Associate Professor Center for Preclinica l and Translational Medicine Research Central Rese arch Facility Sri Ramachandra Institute of Higher Education and Research Porur , Chennai 600 116, India Extn:8170; Tel: 91-44-45928500; Cell: CbH6) www .sriramachandra .edu .in Academ ic Editor , PLoS One , Public Library of Science, San Franci sco, USA Website: Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=Subramaniam+JR Research Gate: https://www.researchgate.net/profile/Jamuna Subramaniam Google Scholar : https://scholar.google.co.i n/citati ons?use r=T4Z2VMAAAAAJ&h l= en Quote : "I remain an Optimist. Not that I can give any evidence that right is going to prosper, but because of my unflinchingfaith that right should prosper in the end" Mahatma Gandhi NIH-000368 From: Date: (b)(6) Sat, 21 Mar 2020 07:37:38 -0400 Mr Chiogna Re: The Virucidal Efficacy of Blue light (222 nm) UV light with Respect to To: Subject: Corona Virus Thank you for your note. AS Fauci Sent from my jpbone On Ma r 21 , 2020, at 2:46 AM, Mr Chiogna wrote: Dear Dr. Fauci , My name is John Chiogna. I work as a Physics teacher in Vancouver British Columbia. Attached below is a short write up on a possible inexpensive means of quickly san itizing private and public locations such as care facilities, hospitals , schoo ls, chu rches , government workplaces, arena s, etc . I'm sure that the efficacy of 222 run light has been considered by some already. Howeve r, I have included some numbers that take into account human safety limits , as well as references to peer-reviewed journa ls that support my claims . It is my hope that this may make this simp le idea more p lausible. Please consider the merits of such an idea and implement it as you wish , thank you . Yours since rely , John Chiogna 51What is the Viruc idal Efficacy of Blue light (2 ... Thise-mailis intended onlyfor the individualnamed above. Any distribution,use or copyingof this e-mail or the information 1tcontainsby other than on Intended recipientIs unauthonzed. If you have received this e-mail in error, please delete immediately. NIH-000369 From: Date: Sat, 21 Mar 2020 07 :35:58 -040 0 To: DMID Word Nerds Subject: Fwd: Note from a NIH "alumnus"re . SARS-CoV-2 (b)(6) Sent from my iPhone Begin forwarded message: From: Robert Wiskocil Cb)<6J > Date: March 21, 2020 at 4:30:43 AM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6>: Subject: Note from a Nm "alumnus" re. SARS-CoV-2 Dear Dr. Fauci, I used to work in Bob Goldberg's division at the NCI (Blgd 37) from '78-'80. I'm now a rbeumatologist in the SF Bay Area. I' m including a Letter to the Editor (submitted 3.19.20) for the NEJM that proposes a costeffective therapy for COVID-19. (I've included a slightly longer version with more references): N-acetyl cysteinefor Coronavirus Robert Wiskocil, MD Affiliation : Private Practice Rheumato logy Date: March 19, 2020 (b)(6) Telephone Number: (b)(6) Email: Abbreviations: N-acety l cysteine (NAC),porcine epidemic diarrhea virus (PEDV) In a recent letter to Cell Research , Remdesivir and chloroquine were found to inhibit the SARS CoV-2 (COV ID-19 ) virus activity and replication in Vero cells (1). That study was the basis for current clinical trials involving those medicines . There might be a more cost-effective treatment for the Coronavirus. I believe it will be sensitive to oral high dose N-acetyl Cysteine A final common pathway to host destruction (autophagy) in infected cells in both Corona and Rota viral infec tions involves the Pl3K/AKT/mTOR pathway (2,3). Thi s pathway is inhibi ted by "rapalogues " (like Rapamycin) where the NIH-000370 viral infection is stopped and the host cell survives. N-acetyl-cysteine, a potent anti-oxidant and glutathione precursor, alters the redox state of treated cells and can quench this same pathway (4,5). NAG (N-acetyl cysteine) has been used to rapidly clear Rotavirus diarrheal infections in children (6). Furthermore, the porcine epidemic diarrhea virus (PEDV) coronavirus has been studied in Vero cells. In vitro, NAG blocks that particular virus (7), and in vivo, NAG blocks intestinal damage caused by this virus (8). NAG likely provides a "redox clamp" on the autophagy pathway this virus exploits. Since the PEDV coronavirus is effectively blocked in Vero cells by NAC, the SARS-GoV-2 (COVID-19) will likely also be inhibited. This test should be done, and if positive, clinical trials ought to follow. Doses of 2.4-3.5 g/d of NAC have been used to treat patients with Lupus (4). That dose is well tolerated and inexpensive . If NAC were effective in symptomatic patients, it could add a cost-effective measure of protection to healthcare workers and exposed individuals . References: 1) Wang , M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res Y Yin et. al. Pl3K-AKT-mTOR axis sustains rotavirus infection via the 4EBP1 mediated autophagy pathway and represents an antiviral target. Virulence , 2018 VOL. 9, NO. 1, 83-98 3) J Kindrachuk et. al, Antiviral Potential of ERK/MAPK and Pl3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis Antimicrobial Agents and Chemotherapy February 2015 Volume 59 Number 2 p 1088-1099 4) Zhi-Wei Lai, et al, N-Acetylcysteine reduces disease activity by blocking mTOR in T cells of Lupus patients, Arthritis Rheum. 2012 September; 64(9): 2937-2946 5) C. C. Xu , S. F. Yang , L. H. Zhu , X. Cai , Y. S. Sheng , S. W. Zhu , J. X. Xu, Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets, Journal of Animal Science , Volume 92, Issue 4, April 2014 , Pages 1504- 1511, https ://doi.org/10.2527/jas .2013-6755 NIH-000371 6) C Guerrero et al. N-Acetylcysteine Treatment of Rotavirus-Associated Diarrhea in Children Pharmacotherapy 7) Xu X, Xu Y , Zhang Q , et al. Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signaling pathways. Vet Microbiol. 2019;232:1-12. 8) Wang L, Zhou J, Hou Y, et al. N-Acetylcyst eine supplementat ion alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus . Amino Acids . 2017;49(12):1931-1943 . I hope you find this helpful! Sincerely, (b)(6) Robert Wiskocil MD (b)((i} NIH-000372 From: (b)(6) Date: To: Subject: Sat, 21 Mar 2020 07:19:19 -0400 PITTMAN,RYAND Re:Preparingfor COVID-19in my Neighborhood Sent from my iPhone On Mar 21, 2020, at 12:10 AM, PITTMAN , RYAN D < rpi ttman @ email.sc.edu>wrote: Good Evening Dr. Fauci, My name is Ryan Pittman. I live in (b)(6) South Carolina, right outside of (b)(6) The virus is here. Seeing as this is likely to get worse before it gets better, I want to be prepared to help people in my neighborhood when they start developing symptoms and the hospitals are not ready for them. How do you recommend I go about doing this. I am prepared to acqui re a modest stockpile of supplies to give to those suffering through this, but I am not entirely sure what would be best. The hope is to take your information and pass it on to those in other neighborhood s in the area, so we can come together and help as many people as we can get through this pandemic. Thank you for your time. Ryan Pittman, MS University of South Carolina Department of Statistics NIH-000373 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sat, 21 Mar 2020 02:19:38 +0000 Priscilla Kelly RE:Thank you from Science Priscilla : Thank you for your kind note. Best regards, Tony From: Priscilla Kelly Date: Friday, March 20, 2020 9:20 PM ------~~ To: Fauci,Anthony (NIH/NIAID) [E] Subject: Thank you from Science -------- CbH6J> Dear Tony, I wanted to send our sincerest thank s from everyone at Science, for the supe rb leadership that you are showing the United States (and the world) during this pandemic. Thank you also for educating the public that the most productive countermeasures will be based on data-dr iven science. We wi ll continue to do our part here at Science to publish the strongest COVID-19 studjes to help advance research as rapidly as po ssible. All the best, Priscilla Priscilla N. Kelly , Ph.D Biomedicine Editor, Science NIH-000374 From: Date: To: EOP/NSC,----- Fauci, Anthony (NIH/NIAIO)[E) Fri, 20 Mar 2020 22:45:24 +0000 Stephen Hahn;Redfield, Robert R. (CDC/OD);Birx, Deborah L. -:a~'"" ~c=~ Subject: Treatment Document Att achments: dblnformation for Clinicians on COVID-19Therapies31hcl - wi th Fauci and Lane tracked changes showing.docx, dblnformation for Clinicians on COVID-19 Therapies31hcl - with Fauci and Lane tracked Clean copy.docx Team: As per my discussion with Steve a few minutes ago, I have made some changes in the document. ~)(5) ~)(5) -------------------------- I am attaching a tracked version of the document that was your FINAL as we ll as a clean copy wi t h all of the changes accepted. Please take a look and Steve said that he wou ld like to set up a qu ick call to discuss after you have had a look. I am very sorry to come in with these changes at this late point, but I rea lly did not get a chance to have a good look at the document as I was in a car. ~)(5) Thanks, Tony Anthony S. Fauci, MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : ~)(~ FAX : (301 496-4409 E-mail : ~)(~ The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000377 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 21:08:04 +0000 (b)(6) To: Subject: Attachment s: therapy dblnformation for Clinicians on COVID-19 Therapies3.docx Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-000378 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 11:52 :45 +0000 Lerner, Andrea (NIH/NIAID) [El Mars ton, Hilary (NIH/NIAID) [El RE: Modeling of COVID-19 from Mike Levit It would be a good idea to get a feel for what our modelling people think about this . Thanks, Tony From: Lerner , Andrea {NIH/N IAID) [E] Se nt : Thursday, March 19, 2020 3:11 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b)(6) _,(b ::-;: )...,. (6) ""' Cc: Marston, Hilary (NIH/NIAID) [El Subject: FW: Modeling of COVI0-19 from Mike Levit (b)(6) Dr. Fauci, Just re-upping this as your in box is hopefully less stuffed now. Larry Tabak letting you know about this modeling work . See original email at the bottom from My summary is below and if you'd like me to ask some NIAID modeling SM Es what they think, let me know . Andrea ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Dr. Fauci- I took a look at this and here is my impress ion: (b) (5) NIH-000379 I would defer to our modeling experts at NIAID as to the valid ity of his model - let me know if you' d like me to reach out to them . (b) (5 . CCing Hilary if she has additional thoughts. Sincerely, Andrea --------10:59 From: "Fauci, Anthony (NIH/ NIAI D) [E]" Date: Monday, M arch 16, 2020 at PM To: "Lerner, And rea (NIH/N IAID} [E)" -------~~ Subject: FW: Modeling of COVID- 19 fr o m Mike Levit --------- (b)(6)> Cb)( > Please t ake a look and see what you think. From: Tabak, Lawrence (NIH/OD) [El Se nt : Friday, March 6, 2020 8:46 PM To: Collins, Francis (NIH/OD) (E] (b) ~ > ---------- -----~~ ------- (b)(6)>; --------- Cc: Lauer, Michae l (NIH/OD) [E] Subject: Modeling of COVID-19 from Mike Levit (b)(6) Fauci, Anthony (NIH/N IAID) [E] (b)(6)> Francis, TonyMike Levit t (Nobel prize in Chemistry, 2013) sent the attached modeling of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated t hat he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estima tes for case fatality ratio . His first report from 2-Feb is attached as wel l as his most recent two -part report. Larry NIH-000380 From: Date: (b)(6) To: Subject: Attachments : Fri, 20 Mar 2020 06:56 :52 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: COVID-19 multidisciplinary FAQarticle COVIDQuestion_v2.docx, ATT0000l .htm Beg in forwarded message: ---------------------=-:-:-= -------- From: Andreas Kronbichler Date: March 20, 2020 at 3 :50:20 AM EDT To: "Fauci , Anthony (NIH/NlAID) [E]" (b)(6) (b)( (b)(6) Subject: COVID-19 multidisciplinar y FAQ article Dear Prof. Fauci, May I briefly introduce myself: My name is Andr eas Kro nbichler, I am nephrologist based in Austria, and do have an interest in renal autoimmune disease. As suc h, I know your landmark study about cyclophosphamide use in GPA published in 1971; and I have learned that you were involved in the management of David Fajgenbaum MCD, whose story is so impressive. I am contacting you and asking you for your help regarding a multidisciplinary FAQ article we would like to write and which does make sense in our eyes, given the rapid spread of this devastating infectious disease. We would lik e to invite experts in the field to comment on a selected topic and then summa rize this as a paper with hopefully high impact in the field. If you agree , can you answer 1his question (around 400 words max. ): Can you describe the pathophy siology and some of the immunological aspects of SARS-CoV-2 infection and COVID-19disea se ? I wou ld be personally very honored to work together with you. A select ion of topi cs is attached to this e-mail. With best regards, And reas Kronbichler M.D. Ph.D. NIH-00038 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 10:42:16 +0000 To: Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIAID) [El;Barasch, Kimberly (NIH/NIAID) [Cl;Folkers, Greg (NIH/NIAID) [El;Myles, Renate (NIH/OD) [El Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Francis. From: Collins, Francis (NIH/OD) [E] (b)(6)> Date: Friday, March 20, 2020 5:29 AM To: Fauci, Anthony {NIH/NIAID) [E)-----(b =)c-c (= > Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6) Barasch, Kimberly {NIH/NIAID) [C] (b)(6) ; Folkers, Greg (NIH/NIAID) [El (b)( ·>; Myles, Renate (N -:l-:--:H/-:--: 0:-:D-:-) :=[E :-;:: ] ====~ --(b... )( = 6) Subject: RE:COVID-19 science brainstorm at NIH, and town meeting Thanks , Tony . The town meeting runs from 1 to 2. If your press conference runs late, I'd be glad to have you call in at any other time during that hour - we would squeeze you in! Francis From: Fauci, Anthony {NIH/NIAID) [E] CbH > Date: Thursday, March 19, 2020 10:54 PM -----~~ To: Collins, Francis {NIH/OD) [E] (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El CbH ; Barasch, Kimberly {NIH/NIAID) [C] ________ Cb _>_ <> ; Folkers, Greg (NIH/NIAID) [E] (b)(6) Subject: RE:COVI0-19 science brainstorm at NIH, and town meeting Francis: I was just told by the VP's office that I will have to be at the press conference between 11 :00 and 12:30 PM. And so I definitely cannot conference starts and finishes late, I may end before 1:00 PM and so I will likely be Regard ing the session of IC Directors, this be at NIH physically at 1:00 PM and if the press not even be able t elephone in. My guess is that it will able t o phone in. Let us see how tomorrow unfo lds. would be fine with me . Best, Tony Patty : Please let us discuss the phone in logist ics if I canno t physically get there. Thanks,, Tony NIH-000382 From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Thursday, March 19, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~ = (b)(6)> Cc: Tabak, Lawrence (NIH/OD) [E] (b)(6) Subjec t : COVID-19 science brainstorm at NIH, and town meet ing Hi Tony, Nice Facebook session with Zuck! And I heard you were just on CNN, but I missed that one. I did an interview with Sheila Kaplan late this afternoon - and she greatly appreciated your message of apology. I don't think (b)(S). When we spoke yesterday, you were enthusiastic about the convening of a 2 - 3 hour session of IC Directors and SM Esfrom thei r ICs, to brainstorm about additional scientific efforts that could be mounted at NIH to address COVID-19. It looks as if th is can be arranged for an early afternoon next week. Obviously there would be nothing better than to have you there in person for this. While I know your schedule is not exactly under your control, is there any 2 - 3 hour period next week that might have a chance of being open for you? If not, who would you want to be the presenter of the current portfolio of NIAID investments? (b)(S) We have the NIH virtual Town Meeting at 1 PM tomorrow . Is there any chance you can come to W ilson Hall in person for that? If not, is there a chance you can call in? I will serve as moderator, and after a few minutes of opening remarks, would hope to turn this over to you for ten minutes or so of the unique Fauci perspective. After that, Larry and Alfred will talk for a few minutes abou t the NIH COVID Response Team, and Jim Gilman w ill talk about what's happening at the CC. Then we' ll open it up to questions, which we can accept in real time from the estimated 20,000 staff who will be logged in. But you wouldn't need to stay for all that- if we could somehow have your participation (either in person or on the phone) from about 1:10 to 1:20, that would be really wonderful. Please let me know if that will be possible . Sorry about the long e-mail. Get some sleep! Best, Francis NIH-000383 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 20 Mar 2020 03:01:09 +0000 Besser, Richard RE: Checking in Rich: Thanks for the note. Much appreciated . I hope that all is well with you. Best regards, Tony From: Besser, Richard Date: Thursday, March 19, 2020 3:59 PM To: Fauci, Anthony (NIH/NIAID) [E] <-----Subject: Checking in -------- ---= (b)(6J> Hi Tony: I hope you are well . I want to applau d you and thank you for your incred ible leadership in communic ating about this pandemic. I wish CDC were standing with you but I know that is not likely to happen . I hope that you will continue to ta lk about all that is being do ne to learn what works to mitigate the impact of the pandemic . Your absence these two days has been quite noticeable. If t here is anything I can do to support you, please let me know. Best regards, Rich Richard E. Besser, MD. President and CEO Office (b) (6) 1 rbesser@rwjf.org Connect with me on Twitter I Linkedln I Facebook Robert Wood Johnson Foundation Building a Culture of Health in Amer ica. Learn more at rwjf.orq. Follow the FoundationTwitter IFacebook I YouTube Pleas e note: In light of the requests made for increased social dis tancing related to the coronavirus (COVID-19), we have closed all three RWJF campuses in Princeton , New York City, and Washington until further notice. All RWJF employees are now working remotely, and all in-person meetings are either cancelled or will be conducted virtually. For the most up-to-d ate inf ormatio n regar ding COVID-19 p lease see resources on CDC, NIH as well as your state heal th depa rtment websites. NIH-000384 From: Date: To: Cc: Subject: - Fauci, Anthony (NIH/NIAID) [E) Fri, 20 Mar 2020 02:39:21 +0000 Jonathan E. Shoag Elemento, Olivier RE: Specimens Would be much more usefu l ---------------------- (b) (5) ----------------=-c-c= From: Jonathan E. Shoag Date: Thursday, March 19, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [E] Cc: Elemento , Olivier Subject: FW: Specimens (b)(6) (b)(6)> _:..__ _:_:-=.!:===~~~-(b)(6) ---------- Hi Dr. Fauci, (b)(5) All the best, Jonathan Shoag M D From: Denny, Joshua (NIH/OD) [El Date: Monday, March 16, 2020 6:17 PM To: Jonathan E. Shoag Cc: Olson. Janet E.• Ph.D.: Cicek. M ine: Olivier Elemento : Thibodeau. Steve : Gebo . Kelly (NIH/OD) [Gl Subject: [EXTERNAL] Re: Specimens Jonathan Thanks for the thoughts and the offer to help . This is indeed something we have discussed I'm copying our chief med ical & science officer, Kelly Gebo. Best, Josh On Mar 16, 2020, at 2:16 PM, Jonathan E. Shoag ---------- Hi Dr. Denny, NIH-000385 (b)(6) wrote : (b) (5) All the best, Jonathan Shoag MD ________ On Mar 16, 2020, at 12:47 PM, Thibodeau, Stephen N., Ph.D. _. wrote: (b)(6J> Dear Jonathan I am one of the Co-Pt's of the Biobank for the All of Us Research Program. Although samples are store here at Mayo, (b) (S L (b) (5) Sorry, the situation is evolving quite rapidly, so no additional information at this point . Hope this helps. Steve From: Jonathan E. Shoag (b)(6)] ....,..,...,....e--,-----------·· Date: Monday, March 16, 2020 3:35 AM To: Biobank Subject: [EXTERNAL] Specimens To Whom it May Concern, I imagine someone has thought of this already - but do you know if (b) (5) NIH-000386 (b) (5) I study prostate cancer epidemiology at Weill Cornell, and in discussing this idea with the head of our precision medicine initiative, was informed that the AllofUs specimens reside at Mayo . All the best, Jonathan Shoag MD NIH-000387 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 22:16:02 +0000 To: (b)(6) Subject: RE:ATTN: Dr. Fauci/ Good ACE bad ACEdo batt le in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf )(6) All of the therapy stuff is anecdotal. We are trying to get randomized instead of just compassionate use for all of these unproven drugs. clinical trials done (b)(6) Best regards, Tony From: Cb)(6J.> Date: Thursday, March 19, 2020 4:19 PM To: Fauci, Anthony (NIH/NIAID) [E] CbH6J> Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-Med 9-2005.pdf ------~~ Fascinating - thanks for sharing with me. The question that I have is whether COVID 19 adheres and infects epithelial cells through the same mechanism as SARS did. Why the increased lethality and how to we decrease likelihood of infection? Just saw today that antiretroviral therapy and malaria agents are being touted as potential therapies - how well founded is this - anything more than anecdotal data to support this? Hope you are getting a few moments of rest. call me if I can help. --------- (b)(6) and do not hesitate to Best, Ken From: Fauci, Anthony (NIH/NIAID) [E] -------Date: Wed nesday, Marc h 18, 2020 7:09 PM (b) ( > To: Cc: '.La-n-e,"""'. C:".": I i":": ff "":"'. (N ~l'."':' H/":"'.' N"."'." IA -:-: 1-:D:-: ) [~El:-:======~ Subject: [EXTERNAL)FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ** A TTENTTON: This emai l origi nated from outs ide the Me dStar netwo rk. ** DO NO T CLICK links or attachme nts unless you recogn ize the sender and know the con tent is safe . The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this NIH-000388 paper argues the opposite , i.e. that ACE inhibito rs might have a benefit and counters the argument to stop ACE inhibitor .s Bottom line is that we really do not know what the effect will be cl ini cally w it h respect to COVID- 19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/N IAID) [El (b)(6)> Date: Wed nesday, Marc h 18, 2020 5:51 PM To: Fauci, Anthony (NIH/ NIAID) [E] (b)(6) Subject: Re: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav irus Nicholls S Peiris M NATURE-M ed 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE in hibitors to increase ACE2. The opposing argument to stop ping ACE inhibitors. From: An thony Fauci Cb)(6) Date: Wednesday, March 18, 2020 at 5 :22 PM To: "Lane, Cliff (N IH/NIA ID) [E]" (b)(6J 1> Subject: FW : ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung inj ury SARS-CoVcoronav ir us Nicholls S Peiris M NATURE-M ed 9-2005.pdf I cannot make hea ds or t ails of this. Please ta ke a loo k an d let me know what you thin k. Thankjs. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Ste McCon Cb)(6) Date: Wed nesday, Marc h 18, 2020 5 :09 PM Subject: ATTN: Dr. Fauci / Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-M ed 9-2005.pdf NIH-000389 "Clearly, the potentia l th erapeutic utili ty of recombinan t ACE2and angiotensin II receptorinhibitors . [ARB's ?)s- already in clinical use for control of blood pressure-for acute lung inj ury result ing fr om viruses and other causeswill be a productive field for invest igation . This is part icularly relevant as we prepare to confront a potential avian flu pandemic, [COVID-19 ? ]armed w ith onlya limit ed numbe r of therapeutic opt ions." Regard s, St eph en D . McConnell, BS, MSc- CCP, CIS Lipidemiologi st - Clinical App lication Specia list Medicare-CMS ACO/MSSP/Direct-Contracting Consultant Medical Science Liaison Mob ile: (b)(6) (b)(6) Sent from my iPhone MedStar Health is a not-for-profit, integrated healthcare delivery system, the largest m Maryland and the Washington, D.C., region. Nationally recogn12ed for clinical quality In heart, orthopaedics, cancer and GI. IMPORTANT. This e-mail (including any attachments) may conta•n mforrnat,on that Is private, confidential, or protected by attorney-client or other privilege If you received this e-mail in error, please delete ii from your system without copying it and notify sender by reply e-mail, so that our records can be corrected ... Thank you. Help conserve valuable resources - only print this email if necessary. NIH-000390 (b)(6) From: Date: Thu, 19 Mar 2020 08:30:51 -0400 To: Holland, Steven (NIH/NIAID) [E] Re: Link to Wash post article re: Kim Hasenkrug Subject: He is a good guy, but this is the second time for him On Mar 19, 2020, at 8:20 AM, Holland, Steven (NIH/NIAID) [E] (b)(6) https://www .washingtonpost.com/health/ trump-ban-on-fetal-lissue-research-blocks -coronavirustrealment-effort/2020/03/18/ddd9f754-685c-11 ea-abef-020f086a3fab story.html Just making you aware of the WP article this morning. This was a surprise to us and I have to believe that Kim was unaware of its preparation or release. Steve Director, Division of Intramural Research Nationa l Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6) voice --------- 301-480-4507 fax (b)(6)emai l Assistant lab: Eva Porti llo Cb)(6) email (b) ( voice ~==~~~-- ----- Assistant to SD: Beth Schmidt ----- (b)( (b) (6) voice From: Karyl Barron CbH6)> Date: Thur sday, March 19, 2020 at 7:35 AM To: Amy Agrawal (b)(6) Subject: Link to Wash post article re: Kim Hasenkrug https://www. wash ingtonpost.com/health/trump-ban-on-fetal-tissue-research-blocks coronavi rus-treatment-effort/2020/03/18/ddd9f7 54-685c-11ea-abef-020f086a3fab _story.html NIH-000391 From: (b)(6) Date: To: Subject: Thu, 19 Mar 2020 08:29:22 -0400 Verma, Seema(FDA/CDER)(CTR) Fwd: Long term care facil ities See below. As per your prior discussion Begin forwarded message: __________ From: Dorothy Franklin Date: March 19, 2020 at 8:22:2 4 AM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E] " Subject: Long term care facilities _, --------- (b)(6) Based on studies at Kirkland care facility indicating staff were spreading the coronavirus to multiple facilities sharing staff, is there or will there be guidance to requi re these facilitie s to re ta in_a dedica ted staff on ly? NIH-000392 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:33:41 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: FW: NEJM: A Trial of Lopinavir - Ritonav ir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 As per my prior e-mail. The medical people likely are aware of this. It j ust came out tonight. (b) (5) -------- (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Se nt : Wednesday, March 18, 2020 10:14 PM Subject: NEJM: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 http://bit.ly/2x91Ji0 Access provided by NIH Library A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 List of authors. • Bin Cao, M .D., et al. Abstract Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV2. Methods We conduc te d a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxyge n (Pao2) to the fraction of inspired oxygen (Fio 2) of less than 300 mm Hg. Patients were randomly assigned in a 1:1 ratio to receive either lopinavir - ritonavir (400 mg and 100 mg, respectively) twice a day for 14 days, in addition to standard care, or standard care alone. The primary end point was the time to clinical improvement, defined as the time from randomization to either an improvement of two points on a seven-category ordina l scale or d ischarge from the hospital, wh ichever came first. Results A tot al of 199 patients with laboratory-confirm ed SARS-CoV-2infection underwent randomization; 99 were assigned to the lopinavir-ritonavir group, and 100 to the standard -care group . Treatment with lopinavir - ritonavir was not associated with a difference from standard care in the time to clinical improvement (hazard ratio for clinical improvement, 1.24; 95% confidence interval [Cl], 0.90 to 1.72). NIH-000397 Mortality at 28 days was similar in the lopinavir - ritonavir group and the standard-care group (19.2% vs. 25.0%; difference , - 5.8 percent age points; 95% Cl, - 17.3 to 5.7). The percentages of pati ents with detectable viral RNA at various time points were similar . In a modified intention-to -treat analysis, lopinavi r- ritonavir led to a median time to clinical improvement that was shorter by 1 day tha n t hat observed with standard care (hazard rat io, 1.39; 95% Cl, 1.00 to 1.91). Gastrointestinal adverse events were more common in the lopinav ir- ritonavir group, but serious adverse events were more common in the standard -care group. Lopinavir- rit onavir treatment was stopped early in 13 patients (13.8%) because of adverse events . Conclusions In hospitalized adult patients with severe Covid-19, no benefit was observed with lopinavir-ritonav i!J t reatment beyond standard care. Future tr ials in patients with severe illness may help to confirm or exclude the possibility of a treatment benefit . (Funded by Major Projects of National Science and Technology on New Drug Creation and Development and others ; Chinese Clinical Trial Register number, ChiCTR2000029308 . opens in new tab.) 1.0 .. 09 l,opln.11v11 - flton.11v,r & o.a l 01 J-~ 06 OS ~ OJ E :, 02 :i u O• 01 0 .0 N o. •t Risk lol)1nav1t- rito1t.11v1t '}9 Control 100 • I 12 93 100 93 9& gg 18 28 16 20 so 33 26 60 39 32 Figure 2. .__________________________ 22 ,o _. ime to Clinical Improvement in the Intent ion-to-Treat Population. Disclaimer: Any third-party material in this emaiJ has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It docs not necessarily represent my views nor those ofNIAID , NIH, HHS, or the U.S. government. NIH-000398 Fauci,Anthony (NIH/NIAIO)[E) From: Date: Thu, 19 Mar 2020 02:20:05 +0000 sheila.ka plan@nytimes.com Collins, Francis {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Dr. Collins To: Cc: Subject: Sheila: I do not recall getting a request from you. I am completely swamped and so it may have just gotten bur ied in a pile and I did not see it. I apologize. I am mostly locked into the Whi t e House where we must give up our phones and so it makes it very difficult for me to return calls. I talk to Francis all the time and he is very well versed in these issues. He will do a fine job of providing you with the information you need. If you would still like to speak w ith me later on, we can try to make that work. Again, I am sorry if you felt snubbed. Best regards, Tony From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myl es, Renate (NIH/OD) [El Cc: Burklow, John (NIH/OD) [El (b)(6) (b)(6)> ; Fine, Amanda (NIH/OD) [El (b)(6) Subject: Re: Coronavirusinterview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Ma r 18, 2020 at 3:56 PM Myl es, Renate (NIH/OD) [E] (b)(6) wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule . The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVI D questions. We can check in with NIAi D to see what we can do. Thanks, Renate NIH-000399 From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E] >; Burklow, John (NIH/OD) [E] (bH > (b)(6)>; Fine, Amanda (NIH/OD) [E] Subject: Re: Coronavirus interv iew with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available . Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 Cell: ------ (b)(6)1 Sheila Kaplan NIH-000400 Reporter, Washington Bureau The New York Times Office: (202) 862-0312 Cell: ----- (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)(6) NIH-00040 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02:13:35 +0000 Collins, Francis (NIH/OD) [El Conrad, Patricia (NIH/NIAID) [El RE:Coronavirus interview with Dr. Collins Francis: Go for it. We need all the help we can get Sheila. I will write and apologize. Best, Tony I do not remember getting a request from (b)(6)> From: Collins, Francis (NIH/OD) [El -------Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E] -------=Cc: Myles, Renate (NIH/OD) [El (b)(6) (be)(= > (b)(6)>; Burklow, John (NIH/OD) [E) Subject: FW: Coronavirus interview with Dr. Collins Hi Tony , I could use your guidance on press interviews. I understand that only Task Force members are supposed to do television events - and I declined the NewsHour tonight to be consistent with that. But what is your preference for printed press pieces, when you can't do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing. An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would lik e some help with? Francis From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/OD) [E] (b)(6) Cc: Burklow, John (NIH/OD) [E]=====~ (b~)(~6)];Fine, Amanda (NIH/OD) [E] (b)(6) Subject: Re: Coronavirus interview with Dr. Collins Hi Renate, Thank you.... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [E]______ NIH-000402 Cb _)_(6) _ > wrote: Hi Sheila: The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions. I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlant ic was really intended as a profile , but ended up covering a lot of COVID questions . We can check in with NIAID to see what we can do . Thanks, Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) (b)(6)>; Burklow, John (NIH/OD) [E] CbH >; Fine, Amanda (NIH/OD) [E] CbH > Subject: Re: Coronavirus inte rview with Dr. Collins -------Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't t alking, either . This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote : Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be availa ble. Thank you, Sheila NIH-000403 Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: {202} 862 -0312 Cell: (b)( NIH-000404 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:12:30 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: typo, etc. fixed , (b) (6) Too long for me to read From: Erik Nilsen Date: W ednesday, March 18, 2020 10: 11 PM To: Fauci, Anthony {NIH/ NIAID) [E] _ __:_.:...:!= (b ~____, )~(6):;-----Subject: typo, etc. fixed , -----~~ ______ (b)(6) Hi Dr. Fauci, I'm now back in my office. I typed the orig inal message on phone. I just noticed a bunch of typos. Below is a better version. Regards, Erik Dear Dr. Fauci, You're beyond busy but I hope you read this message. (b) (4) I'm only mentioning this so you don't think I'm a paranoid freak. I'm convinced you already know the outbreak is way past the point of containment, and, unfortunately, herd immunity will soon ensue. Then, outbreak 2 will happen shortly after, and, hopefully, not ad infinitum. I'm writing to make sure you already know or at least suspect everything I'm about to tell you. I need to clear my conscience NIH-000405 because it's possible (albeit unlikely) that some of what tell you is new and possibly useful in, at least, saving lives in the USA. I'm a physicist and have been modeling this outbreak since January. My panic started minutes after I learned tvSM people left Wuhan around January 22 a few days before the CCP starting locking the country down. The SM peop le scattered to 13,000+ cities in China to visit family & friends for the Lunar Festival (Ch inese New Year). I 've been communicating with quite a few people around the world including an NYU epidemiologist (b)(6) . We 've both been warning our families, to mostly deaf ears at first, since January. It's been f rustrating and exhausting, but, finally, most are as prepared as possible for what's about to happen. I have lots of information about China due to my business, scientif ic, friendship, and other ties with many there, including immunologists & virologists at top-tier institutions and laboratories . My WeChat account (like Skype / Whatapp) was blocked by the CCP for 3 days late February / early March, but, after a warning message, it is now unblocked . I'm willing to share with you everything I know, think I know, or seriously suspect. Here are a few examples: I'm confident t hat China stop counting dead COVID-19 infected bodies since tvJanuary 7 , 2020. They'v e been add ing fabricated data daily to show (to save face) the world and their own people an impressive flattening of China outbreak curve . It's easy to prove this via data analysis because, for example, improbable coincidences occurred in much of the data. My suspicions were eventually confirmed by at least two of my sources in China (b)(6) ). The data posted by it has mis led the world into a false sense of security wrt death rate, age vs death, and other things; that is, if people analyzed the world's data including China, the -----------------Chin a is not only garbage, NIH-000406 results are heavily biased towards nonsense, because China's number of cases accounted for the majority of cases worldwide (until a day or so ago). I want to emphasize that I do not believe China intentionally did this to harm the world. I sincerely believe it was done for savingface reasons. Saving face is possibly the most powerful motivating force in China. it is the key to understanding how most Chinese think and why they do what they do. China wanted the world to believe that their Herculean quarantining efforts contained the outbreak . However, I don't think this is true, even after spraying ~billions of gallon of "Clorox" all the country. The number of body bags my contacts told me about about, even after short 15-minutes walk to/from grocery stores in one city during CCP-authorized time slots, suggest the number of deaths is several orders of magnitude larger than what China's posted data indicates . Also, everyone I know in China continues to be in lock down ( ~6+ weeks now), and several went "silent" since about a week ago. This greatly troubles me because those who went silent live in Wuhan. And, yesterday, the CCP revoked permits/license for several Foreign reporters who were trying to learn about about the situation in Wuhan and other parts of China. Several of my sources have told me, in coded language, that the situation in at least Wuhan is not under control at all. In my opinion, China is continues to be extremely concerned about saving face (first) and their economy (second). Their economy is already suffering terribly, and they can't afford to lose the many large manufacturing and other business agreements with foreign countries . This is why I believe they're trying, and succeeding to convince many, to convince most of their population that the outbreak is under control, and it will soon be ok to return to work -- even though it will not be safe, because of current outbreak and outbreak # 2 that will likely start soon. Citizens are not allowed to travel beyond a few stores and, in special cases, their work office, so even people who live their have no idea what's really going on especially in Hubei province including Wuhan. Also, an H 15N outbreak seems to have recently started in NIH-000407 humans in Hunan province (which neighbors Hubei/Wuhan area) . I also have lots of information about USA. Here is some: I believe that many COVID-19 deaths were incorrectly labelled at 2019-2020 flu deaths. The spreading in the USA is almost certainly already homogeneous, because it's been going on since last year without any containment whatsoever. Once massive testing finally starts, this truth/reality will, unfortunately, become obvious. It will manifest itself as hyper exponential (hyperbolic) growth starting a day or two after the millions of testing kits arrive and start being used . The hyper exponential dynamics will eventually evolve to a more accurately calibrated exponential curve once the number to tests is large enough to properly sample the population. I don't think Italy is ahead of us. I think we're ahead and by a large amount. A few other quick bits of info ... The time between infection and death seems to have decreased from about ~20 days (a few months) ago to possibly as short as ~8 days. And, the incubation period seems to be significantly longer. Both, and other data I've looked at, strongly suggest at least one mutation has occurred. This is extremely concerning to me. Another concern is the distribution of deaths vs. age appears to not be as strongly biased, compared to when China data was included, towards older people and/or people with chronic health conditions. Over the past 15+ years, I've traveled to China multiple times per year. I'm pretty sure you've known this for a while, but I truly believe the outbreak tsunmai in the USA is either already happened or is about to happen. As you know, as soon as a surge is sensed, the Tsunami will immediately follow. I believe we missed the containment boat quite a while ago. I've been NIH-000408 closely listening to your comments on TV, and I'm pretty sure you've already come to the same conclusion but don't want to cause mass panic (I understand that). I'm 99% sure that SARS-CoV-2 been spreading in the USA since late November / earl v December last year. (b)(6) (b)(6) --- She works at (b)( 6) and it's possible that everyone in her office got infected too. Who knows how many people in Alaska got it too, but I suspect many tens of thousands possible much more. CbH6) (b)(6) but it has been impossible to get tested. I've called 5 places in Alaska and none wanted me to come it for the test. I've instructed my family and, recently (after family), close friends to get some Alvesco ( ciclesonide) for emergency use only. I've been told by colleagues on the front-line in Japan, China, and Korea, and found several pre-pr int papers, that it is an effective treatment for late-stage COVID-19 patients. Some patients on ventilators who were approaching death have fully recovered after treatment with ciclesonide; ciclesonide has much smaller particles than other corticosteroids so it reaches deeper into lungs and alveolis) . Also, the treatment seems to be a potent suppressor of virus replication. Recovered patients have tested negative shortly after the treatment. Of course, data is limited so can't be sure the treatment is effective. However, because Alvesco has been shown to be safe for infant - 100+ year-old patients, I'm ok with my family and I having it for emergency use. That is, only if healthcare facilities are unable to accept them or me as a patient to treat with ventilator, NIH-000409 corticosteroids ( or whatever the best available treatment is at that time). Having Alvesco in our emergency kits is a much better option that someone avoidably dying because of an overburdened healthcare facility. The other drug I have, and have told my family and some friends to get, is called hyro xychloriquine -- also seem to be effective and safe. But , I think Alvesco is better because it appears to prevent the virus from replicated so infection is wiped out and no longer contagious. Alvesco seems to be two silver bullets in one. I don't believe in coincidences and I'm not a conspiracy theorist, but there are many things out of Iran that also concern me greatly . That's all I say right now. If all of this is old news to you, then I would greatly appreciate a response. It can be as short as "yes". Anyway, I had to share this information with you. Now my conscience is clear . My concern is that it's possible you don't have some of the above info, so I decided to send you this message . I wrote this quickly, so I apologize in advance for any typos, etc . I truly appreciated your efforts, and I'm now confident that President Trump, you, and everyone else involved is doing everything possible to ensure the best possible outcomes. I was deeply concerned a few weeks ago, when the gravity of the situation seemed to not be fully recognized by several in DC. Feel free to call me anytime. My cell # is below. If you do call, I will keep anything we discuss confidential (if necessary) . NIH-000410 Sincerely, Erik Erik A. Nilsen, PhD (b)(6) I www .bio-si gnal.com Bio-Signal Technologies NIH-000411 I Request a demo or quote From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 19 Mar 2020 02 :07:41 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Coronavirus interview with Or. Collins See yellow highlight. Has Sheila Kaplan tried to get to me and has anyone said that I am " ...not talking"? I doubt that. From: Collins, Francis (NIH/OD) [El ------- Date: Wednesday, March 18, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) (El Cc: Myles, Renate (NIH/OD) [El..:....:~==== (b)(6) (b)(6)> ------ ::;..,...,= (b)(6J1> (b ~)~~~;~Burklow, John (NIH/OD) (El Subject: FW: Coronavirus interview with Dr. Collins Hi Tony, I could use your guidance on press interviews. I understand that only Task Force members are supposed to do televis ion events - and I declined the News Hour tonigh t to be cons istent w ith that. But what is your preference for printed press pieces, when you can' t do them all? Wou ld it help the cause for me to accept some of those, or is it better to hold off? If I were to engage, I would certainly seek to provide answers that are 100% with what you are doing . An example is the thread from Sheila Kaplan of the New York Times. I have declined so far but is this the kind of query that you would like some help with? Franci s From: Kaplan, Sheila Date: Wednesday, March 18, 2020 4:10:58 PM To: Myles, Renate (NIH/O D) [El (b)(6)> Cc: Burklow, John (NIH/OD) [El (b)(6); Fine, Amanda (NIH/OD) [El (b)(6)> Subject: Re: Coronavirus interview with Dr. Collins ""':======~~ ---------- Hi Renate, Thank you .... We appreciate it. SK On Wed, Mar 18, 2020 at 3:56 PM Myles, Renate (NIH/OD) [El Hi Sheila: NIH-000412 (b)(6)> wrote : The questions you shared with Amanda were really for Dr. Fauci ; he's our spokesperson on all research specific questions . I know he's really backed up and NIAID is doing the best they can with his incredibly packed schedule. The interview with the Atlantic was really intended as a profile, but ended up covering a lot of COVID questions. We can check in with NIAID to see what we can do. Thanks , Renate From: Kaplan, Sheila Date: Wednesday, March 18, 2020 3:27 PM To: Myles, Renate (NIH/OD) [E) >; Burklow, John {NIH/OD) [E] (b)(6) CbH >; Fine, Amanda {NIH/OD) [E) -------- Subject: Re: Coronavirus interview with Dr. Collins --------- Hi there, Why were we told we could not do an interview, when, after our request, he did one with The Atlantic. You referred us to Dr. Fauci but he isn't talking, either. This doesn't seem fair to us. Can we really not speak to either of them for a story this weekend? Thanks, SK On Sun, Mar 15, 2020 at 4:00 PM Kaplan, Sheila wrote: Dear Renate, John and Amanda: Sheri Fink and I would like to interview Dr. Collins as soon as possible for a story on coronavirus. Can you please let me know when he might be available. Thank you, Sheila Sheila Kaplan Reporter, Washington Bureau NIH-000413 The New York Times Office: {202) 862-0312 ----- Cell: (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202) 862 -0312 ----- Cell! (b)(6) Sheila Kaplan Reporter, Washington Bureau The New York Times Office: (202} 862-0312 Cell: (b)(6) NIH-0004 14 From: Fauci, Anthony (NIH/NIAID) [E) Thu, 19 Mar 2020 02:05:42 +0000 Doug Brust RE:Please Help Date: To: Subject: Doug: Thanks for the note. I have pushed hard on PPEs and as you may know, the POTUS has involved the Department of Defense to provide 5 million N-95 respirators. Hopefully that will alleviate at least a portion of the PPE shortage. Regarding the bars and beaches, I have been screaming on TV 2 to 5 times per night to tell t he younger generation to start tak ing this seriously. I am very surprised that Gov. Desantis has not completely closed the bars, even if they serve food. Take out only. I will bring this up at the Task Force meeting tomorrow. Please take care of yourself. You are an indisp ensable front line warrior. Best regards, Tony From: Doug Brust (b)(6)> Date: Wednesday, March 18, 2020 8:16 PM ------~= To: Fauci, Anthony (NIH/NIA ID) [E) Subject: Please Help -------- (b)(6J> TonyI know you're ridiculously busy so please do not be upset with me, but I am frustrated and yes angry. Again, I think you have to hear from the front line while formulating policy . • • • • Today at the RW clinic I dealt with at least 12 URl's with fever. We cannot test . We have no PPEin clinic . We have a case that tested positive for influen za then SARS-CoV -2--t his scared me the most given I'm trying to r/o COVID-19 by doing PCRfor other respiratory viruses. • On the drive home just now, the gyms, bar-grilles and restaurants still packed. Yes, bars are closed in Florida--but if they serve food (which they all do) .......they're open. Ans, so much for the 50% capacity "suggestion" . • The beaches still ful l for Spring Break. Look at the pies of St Pete. • The DOH? This is from the the FL DOHjust a few hours ago. Yes,this is TODAY. "If a cluster of confirmed cases were to be discovered in Florida, the department wou ld move quickly to engage with and isolate any infected individuals to prevent further spread," said Alberto Moscoso, the state health department's spokesman . I don't have to explain to you how ridiculousthat statement is. NIH-000415 • I've written to our DOH and Governor Desantis three times (includ ing speaking with his staff) asking to close restaurants (aside from take -out), gyms, beaches etc . They are "monitoring". I'm the HIV doc here. I'm it . You know how seriously I take caring for my patients . I have (b)(6) I am putting my life on the line so fo lks can go pump iron, drink beer , have a burger and get a ta n. The band is playing on. Again. Please help. With tons of respect and admiration, Doug NIH-0004 16 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:59 :12 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Coronavirus Please respond to this pe rson. -----Original Message ----From: Be th Abramson ______ __,('b"')..., ~=> Date: Wednesday, March 18, 2020 9:58 PM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coro navims -----~~= (b _)_C_,> Wondering whether it has been considered that only the vulnerable population (those over 60 and/or those with underlying hea lth cond itions)be isolated? I am a (b)(6)psyc hiatrist and after contemplating this option was wonde1ing if this could still reduce the risk to healthca re Systems w ith less disruption to our society. I await your response and apprec iate all you are doing. Beth Abramson MD (b) (6) Sent from my iPhone NIH-000417 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 19 Mar 2020 01:54:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Plaquenil Shortage Causing National Health Emergency for lupus Patients Please respond. From: Bruce Wilder Cb)(6)> Se nt: Wednesday, March 18, 2020 9:52 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Plaquenil Shortage Causing National Health Emergency for Lupus Patients (b)(6) When I tried to refill Plaqueni l today, I learned that there was a nationa l shortage due to doctors prescrib ing Plaquenil to their well patients and themse lves. Recent news articles have reported its success in preventing and treating the coronavirus . What can you do to protect the life of (b) (6) and the millions of other Americans who depend on this drug --------------------------to stay alive? Brenda Wilder (b)(6) NIH-0004 18 Fauci, Anthony (NIH/N IAID) [El Thu, 19 Mar 2020 0 1:53:32 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Please read- idea for Mask Shortage From: Date: To: Subject: Please take a look and hand le. From: Dust i Rainey ~ (b)( ~ Date: Wed nesday, M arch 18, 2020 9:5 1 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subje ct: Please read- idea for Mask Shortage ------- --------- ~= (b)(6) I have an idea to HELPwith t he MASK SHORTAGE! Please don't disregard th is, as this could help our whole country! I know we are concerned as a nation about a mask shortage and I have an idea to what might help. I Don't know who to go to that can help imp lement this and want your input if you think this is a viable aid, then maybe you can help me reach the right people to make the biggest impact, maybe even up to the Coronavirus team in the White House. I have (b) (6) & when I first heard about China quarantin ing 43 million peop le I got worried about masks, I looked up how to sew a mask for myself & family. I found a site that talked about sewing masks for cancer treatment patients and to use 100% quilters cotton for outside & 100% flannel cotton on inside. I started sewing several. I know they aren't the N95, but they are bette r than nothing IF needed. My Dr just told me yesterday not to go anywhere without a mask because it's too much of a risk for my health . It got me thinking. What if while people across the country were in home quarantine, ALL those who know how to sew, they sew these masks to donate in their communities. Not for use against Coronavi rus, but for other things normal masks are used (food prep, non-sickness medical reasons, etc) then they aren't using up the valuab le higher rated masks t hat are needed for doctors, nurses & first responders fighting Coronavirus . These masks can also be washed as needed again and again which will just keep saving other masks. During the WH Press Release this morning, Seema expresses the need for masks & Dr Birx explained how the virus is being spread from surfaces, but that it can't survive in fabric . Which means maybe t hese cloth masks will even help against the spread of the virus. Either way, if you can help ok for these to be used in some manner vs a medical mask being used w ill help pro long the need for more masks and hopefully 3M can have more made by then so we never have to exper ience an lack of masks. What do you think? Dusti Bacon (b)(6) NIH-0004 19 From: Date: (b)(6) To: Subject: Wed, 18 Mar 2020 19:56 :42 -0400 John Brouse Re: Covid19 treatment Thank you for your note. A. S. Fauci Sent from my iPhone On Mar 18, 2020 , at 7 :02 PM, John Brouse ---------- CbH6) >wrote: Sent from Mail for Windows 10 Dear Dr. Fauci I understand that Sout h Korea has been administering Hydroxl Chloroquine, a treatme nt for Malaria, to her citizens that have contracted Coronavirus . Is America considering this drug to help lessen the symptoms of t his virus ? This drug may not prevent anyone from getting ill, but may be a v iable treatment to speed the recovery of individual afflic ted with this disease. Respectfully, John Brouse NIH-000420 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:55:14 -0400 Holly Kreutter Re:airport screenings Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7: 10 PM , Holly Kreutter --------- (b)(6) wrote: Dear Dr Fauci, First of all, thank you for all the hard work you've done to help mitigate the coronavirus outbreak. We're clearly not there yet, but are further along with your efforts. I'm not sure whom to contact about this, and so am writing you because I'm confidant you can get it to the right hands. With regards to the recent closures to Europe and so many Americans coming home, I was at first heartened to hear that all Americans returning would be medically screened and encouraged to/made to quarantine for 14 days. However, I was then disheartened to learn that that hasn't been the case, at least through this past Saturday. (b)(6) was on business in Amsterdam last week and rushed home last Thursday after hearing on Wednesday evening about President Trump's Friday midnight shutdown . He came in through LAXfrom Amsterdam, and wasn't asked any medical questions, nor was he asked to quarantine. Then a friend came in through Miami from Paris on Saturday, and was only given a short medical form to fill out, and then let go. No med ical check, no temperature screening, no further questions. From touchdown to taxi (plus picking up bags), 45 minutes total. Having lived in Singapore through SARS,I'm deeply disturbed. We had medical/temperature checks at all airports, and mandatory quarantines for anyone with possible contact with a SARScontact/patient . The virus was quickly and efficiently contained, and the same has been done in Singapore to date with Covid 19. I was heartened last Friday as I learned that the federal government was on board, and hearing about significant measures that would be taken soon. I must say I've been disheartened as of today, with not enough tests, mask, respirators and ventilators in place. And then hearing of the lack of medical screenings at airports. Please help, as I know you've so desperately been trying to do . And please help to stem any incorrect information going out from our President, information which NIH-00042 1 gives us hope for a couple of days, and then dashes that and puts many into a frenzied despair. We can cope with what's happening, and will continue to change our behavior per the guidelines , but only with information that's accurate. Thank you, and keep safe, Holly Kreutter Virginia Resident NIH-000422 From: (b)(6) Date: To: Subject: Wed, 18 Mar 2020 19:54:24 -0400 NIAID Public Inquiries Fwd: Volunteer status for current nursing students Sent from my iPhone Begin forwarded message: From: Ivan Boc ardo Cb)( Date: March 18, 2020 at7:16:25 PM EDT --------~~ To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: Vol unt eer status for current nursing students CbH6J · Dear Dr. Anthony Fauci, My name is Ivan Bocardo, and am a (b)(6) U.S. Army Medic (68W) deployed to Afghanistan in 2011-2012. I can send you my resume so you can see my skills and abilities that I can bring to the table. Am currently in nursing school ( R.N. ) in Rego Park, Queens with a (b)(6) .._ _________ -=-:,~ My school (----=- .-- ,-.-- ,........,,..._..----..---..--. (b) (6)) has recieved a request from New York Governor Cuomo's office looking for nursing students to help volunteer. However many students like myself are very hesitant to volun teer for the simple fact that it will interfere with our studies and we will still have to comply with class assignments and class exams and especially with final exams this current semester coming up at the middle to end of April 2020. Yet many of my fellow classmates would love a chance to stand up and deliver help during these trying times . However our school will not except any excuses for lateness or absence even though we are now on an online learning as of this moment. So our greatest fear is that we wont finish this semester and will not be able to start next semester ( it starts April 28, 2020 for our school ) ... basically 2 semesters wasted and it will push back our graduation date and furthermore incur more student loans in order to continue with school. This is why I am writing to your office if an exception can be made and we can have OT J ( on the job training for nursing) and recieve credit and for our current semester and possibly our next semester. Many of the students I speak about already have a Bachelor's degree ( I myself have a B.S. In Biology from (b) < ) and many are or have worked as Nurse aides in many NYC area local hospitals with many years of excellent experience. Imagine if you are able to approve this for many nursing school students in j ust the New York City area and Long Island Suburbs .This would be virtually an untapped experienced workforce of literally hundreds perhaps maybe thousands of hands on personnel ready to go to help relieve the over burdened health system workers and provide additional reinforcements due to the coronavirus. In not only my area of New York city but possibly all over the country where we can help provid ing help and additional assistance and reinforcemen ts Dr. Fauci, I am humbly asking for special permission, we all will need all the help we can get. Please consider this option as this can be a win/ win situation for not only NYC residents but for other areas of the country hit hard by this crisis . I have spoken to many of my fellow classmates and they all understand the risk and would be willing to share the burden with the NIH-000423 extreme pressures put on the health care system at this time . Many of us including myself would be w illing to work on site or what ever site you may need us the most, many us fully understand that we could potentially be away from our families for an extensive unknown period of time which we are ready for and prepared for or possibly put our health on the line too. I implore you to give us a chance and only ask for special permission for OTJ in order to fully finish our R.N. nursing degree. Thank you for your time in reading this letter. You are doing one fine heck of job in providing outs tanding information and keeping the public informed Sincerely , Ivan Bocardo Personal Cell phone ____ (b _ )_ (_. 6) NIH-000424 From: Date: (b)(6) Wed, 18 Mar 2020 19:52:49 -0400 Margaret Wilbur Re: coronavirus immunity To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 18, 2020, at 7:25 PM , Margaret Wilbur (b) <6l>wrote: Have we reached a time when it might be useful to prove who is immune to Covid-19? I understand that there is an antibody test already available. If we could identify who is already immune , we could then let those people return to daily life, work safely in essential positions, and feed the economy. I practiced internal medicine in Cleveland, Ohio for (b)(6). I was amazed on a daily basis by the breakthrough that was PCR testing. Right now oldfashioned antibody tests might make a critical difference to us. Margaret Wilbur, MD (b)(6) NIH-000425 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:52:29 -0400 Ronald Frank Re: Dental offices and the coronavirus IMPORTANT Thank you for your note. A.S. Fauci Sent from my iPhone -------- > On Mar 18, 2020, at 7:28 PM, Ronald Frank (b) (6) > wrote: > > Dear Dr Fauci, > > Firstly , I would like to commend you on your expertise and leadership. > > As we develop a compreh ensive plan lo tackle the coronavirus pandemic , I believe that we have failed to address a critical piece of the puzzle to contain the virus. > > I am a physic ian and urologist, but I mn astutely aware of the dental profession. I have a older brothe r who is a practicing dentist and I have voiced my concems to him. > > Each and everyone of us who has had an appointment with a dentist knows the procedure of pressure irrigation in the mouth resulting in a mist and aerosol of secretions and saliva depo siting on the faces of patients, the dentist and on all the surfaces in the treatment rooms. While the dentist wears a face mask, the spray of secretions , in a potential coronavims carrier, widely contaminates surfaces, other employees and patients. > > l pose the question, should dental offices be actively treating patients during this critic al phase in the Coronavirus pandemic? Everything which J have mentioned is corroborated by several practici ng dentists. ls the he CDC and the NTHobligated to set guidelines and restrictions on dental care during this critical time as we try to get control of increasing numbers of cases. Should the ADA take a stronger stance during this crisis? > > r respectiv ely reserve these decisions and recommendations to you and your colleagues Thank you > > Sincere ly, > > Ronald G. Frank , M.D. > 1500 P leasant Valley Way > Suite 201 > West Orange, New Jersey 07052 > 0. 973•73 I•6600 > > > Sent from my iPhone NIH-000426 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:51 :14 -0400 dalt222 Re: Plaquenil for Covid 19 Thank.YOllfor your note. A.S:;,Fauci ~e1it.fri)i1'1 my iPhone 'On Mar 18, 2020 , at 7:41 PM , _________ (b)(6Jwrote: .... Dr Fauci, I hope all is well with you. I am a Dermatologist practicing in the Metropolitan Detroit area. I have done some literature searching on potential treatments for the novel coronavirus and stumbled across a few case case reports from China in 2005 at the time of the SARS outbreak. They detailed some successes in treatment of severe cases with chloroquine. I saw a more recent study showing hydroxychloroquine had better in vitro efficacy than chloroquine. Have you heard of this? Plaquenil is so innocuous, I wonder if we shouldn't just try it. I think you are doing phenomenal work and really presenting a level, measured and realistic view of this epidemic to the world. Please keep up the great work. It is much appreciated David A. Altman MD FAAD Assistant Clinical Professor Division of Internal Medicine Michigan State University College Of Human Medicine Sent from my Verizon, Samsung Galaxy smartphone NIH-000427 From: Date: To: Subject: (b)(6) Wed, 18 Mar 2020 19:50:23 -0400 DMID Word Nerds Fwd: Interest in collaboration on COVID-19antibody development Pls handle Sent from my iPhon e Begin forwarded message: From: Dea Shahinas (b)(6) Date: March 18, 2020 at 7:41:40 PM EDT -------~~ To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6 J:Cc: (b)( > Subject: Interest in collaboration on COVID-19 antibody development Dear Dr. Fauci, We learne d about your research on COVID- 19 at NIAID and are int erested in collaborating with you in order to fast-track our efforts in developing antibodies against this infection. We have two decades of experience with single domain antibody (nanobody) technology. I will provide below a brief summ ary about our company: Virotek is a priva te Canadian biotec h w ith focus on t he development of novel biologics for the treatment of viral infe ctions. Our primary focus area has been in the areas of infecti ous diseases and immuno-on cology in animal and hu man vert icals. (b) (4) (b) (4) NIH-000428 We are also proposing (b)(4) . Please let us know if you are interested and we are happy to arrange for a time to discuss in further detail with you. Best regards, Dea Shahinas Director, R&D Virotek Inc. (b)(6) NIH-000429 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 23:09:32 +0000 (b)(6) (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Nicholls 5 Peiris M NATURE-Med 9-2005 .pdf Attachments : Good ACE bad ACEdo battle in lung injury SARS-CoV coronavirus AnnotatedYELLOWNicholls S Peiris M NATURE-Med 9-2005.pdf )(6) The situation gets confusing. See attached brief commentary and e-mail string. As you can see, I was too tired to make any sense of it. However , my deputy (Cliff Lane) notes that this paper argues the opposite, i.e. that ACE inhibitors might have a benefit and counters the argument to stop ACE inhibi tor.s Bottom lin e is that we really do not know what the effect will be c linically wi t h respect to COVID-19. In any event, (b)(6) Best, Tony From: Lane, Cliff (NIH/NIAID) [E) Date: Wednesday, March 18, 2020 5:51 PM (b)( > ------=--c= To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> Subject: Re: ATTN: Or. Fauci /Good ACE bad ACE do battle in lung injurySARS-CoV coronav irus Nicholls S Peiris M NATURE-Med 9-2005 .pdf A 2005 paper post-SARSadvocating for use of ACE inhibitors to increase ACE2. The opposing argument to stopping ACE inhibitors . From: Anthony Fauci (b)(6) Date: Wednesday, March 18, 2020 at 5:22 PM To: "Lane, Cliff (NIH/NIAID) [E]" (b)(6) Subject: FW: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoV coronavirus Ni cholls S Peiris M NATURE-Med 9-2005.pdf I cannot make heads or tails of this. Please take a look and let me know what you think. Thankjs. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-000430 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Ste McCon Cb ) (6) > Date: Wednesday,March 18, 2020 5:09 PM Subject: ATTN: Dr. Fauci/ Good ACE bad ACE do battle in lung injury SARS-CoVcoronavirus Nicholls S Peiris M NATURE-Med 9-2005.pdf ACE2 and angioten sin II receptor inhibitor s. [ARB's ?]s- already in clinical use for control of blood pressure-for acute lung "C lear ly, the potential therapeutic utility of recombinant injury resulting from viruses and other causes will be a productive field for investigation. This is particu lar ly relevant as we prepare to confront a potent ial avian flu pandemic, [COVID-19? ]armed w ith onlya limited number of therapeutic options." Regards, Stephe n D. McConne ll, BS, MSc - CCP, CIS Lipidemiologist - Clinical Application Specialist Medicare -CMS ACO/MSSP/Dircct-Contracting Consultant Med ical Science Lia ison Mob ile: ----- (b)(6) Sent from my iPhone NIH-00043 1 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 23:03:32 +0000 SWAMINATHAN, Soumya Collins, Francis {NIH/OD) [El [El Subject: RE: Confidential and urgent request regarding ------- (b)(6));Marston, Hilary {NIH/NIAID) Thanks, Soumya. (b)(6) ---------- From: SWAMI NATHAN, Soumya Date: Wednesday, March 18, 2020 6:49 PM To: Collins, Francis (NIH/OD) (El Cc: Fauci, Anthony {NIH/NIAID) (El (b)(6) (b)(6)> ------- (b)(6)>; Marston, Hilary {NIH/NIAID) [El Subject: Re: Confidential and urgent request regarding Dear Francis I am sure you have seen the results which came out today, and are inconclusive. The DG announced the launch of the WHO Solidarity trial, which will hopefully provide a definitive answer to all these questions. Many thanks to NIAID for their support . Warm regards Soumya Sent from my iPhone ------- On 17 M ar 2020, at 18:50, Collins, Francis {NIH/OD) [El (b)(6)> wrote : Hi Soumya, Thanks for any help you can give. Francis ----------- (b)(6)> From: Hudson, Thomas J Date: Tuesday, March 17, 2020 10:15 AM To: Collins, Francis {NIH/OD) [E] ------ (b =)"'" (6) = Cc: Marston, Hilary (NIH/NIAID) [El________ NIH-000432 Cb H_6) Fauci, Anthony (NIH/NIAID) _ [El (b)(6)>; Hudson, Thomas J ------------ (b)(6)> Subject: RE: Confident ial and urgent request regarding Dear Francis, I have not received an response from Dr. Swaminathan to mv message sent yesterday (b)(4) I expect tha t we are not the on ly group try ing to get to WHO leaders. A call from Tony or you may be more successful. -· In add itio n to my contact information below, I can be reached via my cell phone: Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago, IL 60064 ---~= _________ TEL (OF_F_IC_E..:. ) --==== EMAIL (b:)(:6)=--="'=" _, (b)(6) abbvie.com NIH-000433 (b)(6) This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mai l and de lete it from his or her computer. -------- From: Collins, Francis (NIH/OD ) [E] <1 Date: Monday, March 16, 2020 8:43 AM To: Hudson, Thomas J Cc: Marston, Hilary (NIH/NIAID) [E] (b) (6)> (b)(6)> -~-""!""'::~======:!.-.~ ~ >; Fauci, Anthony (NIH/NIAID) ---------(b)( [E] (b) (6)> Subject: [EXTERNAL]RE: Confidential and urgent request regarding Tom, Thanks again for reaching out. I can only imagine (b)(4 (b) (4) The best contacts would be the WHO Chief Scientist Soumya Swaminathan (b)(6) and pote ntially Director General Tedros ~===== (b)=(..-: 6)~- Let me know if you hit a roadb lock with WHO. I m ight then want to weigh in too. Francis -------------------= (b)(6) From: Hudson, Thomas J Date: Monday, March 16, 2020 9:16 AM To: Collins, Francis (NIH/OD) [E] CbH > Subject: RE:Confidential and urgent request regarding -------- Thank you. THOMAS HUDSON NIH-000434 ~· Senior Vice-President, R&D Chief Scientific Officer AbbVie, North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= (b)=(6) = EMAIL _______ (b ._.)..., (6) .., abbvie .com This communication may contain information that is proprietary, oonfidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly proh ibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer . From: Collins, Francis (NIH/OD ) [E] Date: Monday, March 16, 2020 8:14 AM -------- > (b)(6) To: Hudson, Thomas J Cc: Marston, (b)( Hila ry (N ~ IH'.'": / ".": N".": IA:-:ID ~ ):-:[~E"."' ] -::::=====~ Subject: (EXTERNAL] RE: Confidential ""' (b=H=6) and urgent request regarding Hi Tom, Got your message, am looking into it, hope to get back to you later today. Best, Francis ------------- From: Hudson, Thomas J Date: Monday, (b)(6) March 16, 2020 9:10 AM To: Collins, Francis (NIH/OD) [E] ------ = ).-.(= (b 6)>; Collins, Francis (NIH/OD) [E] (b)(6)> Subject: RE:Confidential and urgent request regarding This follow-up message is a duplicate that I am send ing to another e-mail address that I have on file. Dear Francis, aJJLse.udl ng tbis_br.L ei..Rote as a..r.: eau..estJ.oL gu_idao.ce0.,0 pJLe)Lo \li~ sltu.a__tio .n ..w.i..tb _,. ....,.,.., (b) (4) NIH-000435 (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishes, Tom THOMAS HUDSON Senior Vice-President, R&D Chief Scient ific Officer 1 ~ I AbbVle , North Chicago 1 North Waukegan Rd R473, Building AP9-1 N Chicago , IL 60064 TEL (OFFICE) ---= EMAIL _______ (b),..,(6) = (b ._.)..., (6) _, abbvie .com This communication may contain information that is proprietary, confidentia l, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strict ly prohibited. Anyone who receives this message in error should notify the sender Immediately by te lephone or by return e-mail and de lete It from his or her computer . (b) (4) NIH-000436 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:09:47 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ann Beloten (b)(6) Se nt: Wednesday, Marc h 18, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Covid-19 -------~~ --------- (b)(6) Dear Dr. Fauci, I am writing to you because I have a question regarding Covid-19. How come you do not tell the compete truth to t he American people regarding this virus? All I hear is the bad facts about it . Why not give people some help and tell us t he good facts about it? Good facts such as the number of actual patients is very small compared to the whole population, most people who get it make a full and complete recovery. Are you enjoying t he senseless panic you made? Panic where people are hoarding food/goods , stealing full shopping carts from the elderly, losing their jobs/wages, inadequate education now that schools are closed. The number of people who will actually be sickened by the virus will be dramatically dwarfed by the people who lose their jobs, receive a poor education despite the ir teachers best efforts and miss out on once in a lifetime events such as weddings, graduations, communions. What you are doing is not right for the American people!! You need to stop playing GOD and tell the people the complete truth!! The country and the people need to get back to our normal lives NOW!! Sincerely, Ann Beloten NIH-000437 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 20:07:28 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Rapid diagnostic support for Covid-19 Date: To: Subj ect : Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Tony Lemmo (b)(6)> Date: Wednesday, Marc h 18, 2020 3 :52 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Rapid diagnostic support for Covid-19 ------~~ -------- CbH6)> Hi Dr Fauci, Hello from ------------ (b)(6) I'm sure you are swamped . I'll be brief . I am CEOof the world's leading provider of dispensing equipment for the diagnostics market, BioDot Inc. We have been around for 25 years and provide enab ling technology to virtually every rapid immunoassay and molecular diagnostics company in the world. We are actively involved today with companies around the globe to help commercialize lateral flow point of care products to help fight Covid-19. If there is anybody in your organization or on the task force that could help facilitate gett ing us involved with companies looking to produce tests - we are here to help! For example we are actively working with Biomedomics to get their LFDtest into the community as fast as possible. We will move heaven and earth to help the country in any way we can . Thank you for all you have done and best of luck in fighting th is pandemic (b)(6) NIH-000438 Tony Anthony V. Lemmo, Ph.D CEO and President BioDot Inc. 2852 Alton Parkway Irvine, CA 92606 p (b) (6) F 949-440-3694 www .biodot.com NIH-00043 9 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [El Wed, 18 Mar 2020 20:05:50 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Fabric Face Masks Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: AmiSimms (b)(6)> Date: Wednesday, March 18, 2020 4:01 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: Fabric Face Masks -------::-::-=, (b)((;)> -------- Dr Fauci, Thank you for your guidance and expert ise at this difficult time . My friend and I are quilters. She lives in (b)(6) and I live i (b)(6) _ She has created a pattern fo r a fabric face mask. We read Dr. Tufekci's oped in the NYT yesterday and have been brainstorming togethe r ever since on ways we can help. htt ps://www .nyt imes.com/2020/03/17 /opinion/ coron avirus-face-masks. htm I Several years ago I mobilized quilters throughout the US and we raised mo re than $1.1 million for Alzheimer's Disease research . All grass roots, all vo lunteer . There are 7-10 million quilters in the US. My friend and I would like to make a fabric face mask pattern available at no charge so that quilters, sewers, and crafters can make face masks. We understand these are nowhere near medical grade, but they would be better than nothing at all. {See research cited in link above .) They would be made from fabric scraps and supplies on hand; no trips to the fabric store would be necessary. At this t ime there are no masks available to the public at all. Sewing for a cause would give purpose to those of us staying home . Wearing a mask on rare occasions when we do venture outside has the benefits signaling others to step back even if the masks do not protect against transmission of the virus . NIH-000440 We are just two individuals wanting to help. I've been advised by an attorney that sharing t his free pattern might open us up to scrutiny from regulatory agencies or possible law suits . We don't want to step on any toes, nor do we want any legal entanglements . Could the NIH make t his pattern available? Or the CDC?There are millions of sewers who would be delighted to step up and help right now. It would be great for morale , and even t hough it's one step up from nothing , IT IS SOMETHING. This could even be scaled beyond indiv iduals making fabric face masks fo r th emselves. Ma sks could be sewn for ot hers . Could we please work with you? Thank you for your consideration , Ami Simms (b)(6)and Emanuela D'Amico (b)(6) NIH-00044 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 18 Mar 2020 19:07:06 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid-19 symptoms outside of China Point this person in the righ t direction Anthony S. Fauci , MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recip ient. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: WW (b) (6) Date: Wednesday , March 18, 2020 3:05 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Covid-19 symptoms outsideofCh ina ------~~ (b)(6) > Dear Dr. Fauci, Many insist on coughs as one of the requirements for self-isolation or testing for covid-19. However , l have read about instances where coughs were not experienced by those who tested positive. ls it possible to share a list of covid - 19 symptoms that *exclude* the patients in China and perhaps France due to their fairly high numb er of smokers? Does coughi ng remain a symptom ? l am concern ed about the health of our nursing hom e resideni s, as well as the financial well-b eing of service sector workers. Thank you, Winnie NIH-000442 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 18:27 :08 +0000 To: Redfield, Robert R. (CDC/OD);Stephen Hahn;Birx, Deborah L. EOP/NSC Cc: (b)( ;Troye, Olivia EOP/NSC;Short, Marc T. EOP/OVP;Miller, Katie R. EOP/OVP;Hicks, Hope C. EOP/WHO;kellyanne conway Subject: Follow -up of today's conversation Folks: (b) (5) --------- 5J. Hap py CbH to discuss. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-000443 accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-000444 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 18 Mar 2020 15:09 :54 +0000 To: Subject: (b)(6) FW: Bloomberg: 99% of Those Who Died From Virus Had Other Illn ess, Italy Says Look at the hypertension percentage Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Wed nesday, Marc h 18, 2020 9 :52 AM Subject: Bloomberg : 99% of Those Who Died From Virus Had Other Illness, Italy Says 99o/oof Those Who Died From Virus Had Other Illness, Italy Says By Tommaso Ebhardt, Chiara Remondini , and Marco Bertacche March 18, 2020 , 8:56 AM EDT More than 99% of Italy's coronavirus fatalities were people who suffered from previous medica l conditions, according to a study by the country's national health authority. After death s from the virus reached more than 2,500, with a 150% increase in the past week, health authorities have been combing through data to provide clues to help combat the spread of the disease. NIH-000445 Prime Minister Giuseppe Conte' s government is evaluating whether to extend a nationwide lockdown beyond the beginning of April, daily La Stampa reported Wednesday. Italy has more than 31,500 confirmed cases of the illness. Italy Coronavirus Deaths By prior illnesses(%) 0 .8 7 No other illness 25.1 1 other illness- --3 48 .5 or moreillnesses 25 .6 2 other illnesses-- Source: ISS Italy National Health Institute, March 17 sample The new study could provide insight into why Italy's death rate, at about 8% of total infected people, is higher than in other countries. The Rome-based institute has examined medical records of about 18% of the country 's coronavirus fatalities, finding that just three victims, or o .8% of the total, had no previous pathology. Almost half of the victims suffered from at least three prior illnesses and about a fourth had either one or two previous conditions. More than 75% had high blood pressure, about 35% had diabetes and a third suffered from heart disease. The average age of those who've died from the virus in Italy is 79.5. As of March 17, 17 people under sohad died from the disease. All of Italy's victims und er 40 have been males with serious existing medical conditions. While data released Tuesday point to a slowdown in the increase of cases, with a 12.6% rise, a separate study shows Italy could be underestimating the real number of cases by testing only patients present ing symptoms. NIH-000446 According to the GIMBE Foundation, about 100,000 Italians have contracted the virus, daily Il Sole 24 Ore reported. That would bring back the country's death rate closer to th e global average of about 2%. - With assistance by Karl Maier NIH-000447 From: Date: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 18:13:38 +0000 To: Fauci, Anthony (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];A uchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:Covid-19 coverage in Nature Reviews Immunology Dear Alexandra, Thank you for your kind words. Yes, we can send yuu references of notable papers My chief of staff, Greg Folkers (cc'd here), will be my conduit/surrogate. Regards, AS Fauci From: Alexandra Flemming Date: Tuesday, March 17, 2020 10:26 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Covid-19 coverage in Nature Reviews Immunolo gy -----~ = Dear Tony, Thank you again for contributing the fabulous year in review article to Nature reviews Immunology last year! Given the current pandemic, we can only imagine how incredibly busy you are at the moment. At Nature Reviews Immunology we have decided that we would like to introduce an in-brief section that provides a brief overview of the most notab le/important research on SARS-CoV -2, particular ly with regards to its immunopathology and vaccine development. To this end, we are recruiting a small number of advisors to point us in the right direction - this wou ld involve no actual writing, just sending us references to the papers as and when they come out . Would you, or a member of your team, be willing to act as an advisor for this project, by sending us between 1-5 references for notable papers per month? We feel that particularly in th is fast evolving situation, it is of paramount importance that amongst the deluge of data, scientists are guided towards the most important papers. I look forward to hearing from you , With best regards, Alexandra Dr AlexandraFlemming NIH-000448 Chief Editor Nature Reviews Im munology Natu re Research 4 Crinan Street, London Nl 9XW, UK (b)(6) a.f lem ming@natu re .com www .nat ure.com/n ri 150YEARS i~~ CELEBRATING 1869-2019 nature DISCLAIMER:This e-mail is confidential and should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delet e it from your mailbox or any other storage mechan ism. Springer Nature Limited does not accept liability for any statements made wh ich are clearly the sender's own and not expressly made on behalf of Springer Nature Ltd or one of their agents. Please note that Springer Nature Limited and their agents and affiliates do not accept any responsibility for viruses or malware t hat may be contained in th is e-mail or its attachments and it is your responsibi lity to scan the e-mail and attachments (if any). Springer Nature Limited . Registered office: The Campus, 4 Crinan Street, London, Nl 9XW. Registered Number: 00785998 England. NIH-00044 9 From: Date: (b)(6) To: Cc: (NIH/NIAID) [E] Subject: Attachments: Tue, 17 Mar 2020 10:42:33 -0400 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C];Lane, Cliff (NIH/NIAIO) [E];Marston , Hilary Fwd: Invitatio n: BIO Coronavirus Collaboration Initiat ive INVITATION_FauciBIO COVID19 Virtual Summit 15Mar2020.pdf, ATTOOOOl.htm Let us discuss and decide one way or another. Begin forwarded me ssage: From: Hannah Dorsey Date: March 16, 2020 at 3 :51:02 PM EDT To: "Fauci, Anthony (N lH/NlAID ) [E] " Cc: "Conrad, Patricia (NIH/NIAID) [E]" Hilary (NIH/NIAID) [E]" --------,;-, = --------- >, "Marston, Phyllis Arthur :r-----,--- (b) C6 b, Subject: Invitation: BIO Coronavirus Collaboration Initiative Dear Dr. Fauci, On behalf of BIO, I wou ld like to inv ite you to participate in our multi-stakeholder COVID19 Collaboration Virtual Summit which will take place March 24-25. We are hosting this summit in order to facilitate near-term collaboration among indust ry, government, academic and non-governmental experts to help confront this growing and unpredictable publ ic health crisis. We would like you to be a speaker during the Plenary session on March 24th. We would like you to give 5-10 minutes of opening rema rks to the Summit participants. Please note that the plenary session of the event will be open to the press, while the remaining sessions will be closed to just invited guests to ensure a robust discussion and maximum collabo ration. You are welcome to attend any of the subsequent Breakout sessions scheduled over the two days. This virtual meet ing will take place over two days: • March 24th: 10:00am -11:45am - Plenary Session • March 24th: 12:00pm - 2:30pm - Treatment Break Out Session • March 25th: 10:00am - 12:30pm - Prevention Break Out Session • March 25th: 1:00pm - 3:30pm - Diagnostics Break Out Session NIH-000450 Attached is the full invitation to our event from our CEOJim Greenwood, the full agenda will be to follow. Please let us know if you would be available as a speaker for the Plenary session on March 24th . Best, Hannah Dorsey Coordinator, Health Policy Biotechnology Innovation Organization (BIO) 1201 Maryland Ave. SW, Ste. 900 Washington, DC 20024 Office: (202) 962-6644 hdorsey@bio.org ww w .b io.org NIH-000451 From: Date: (b)(6) To: Subject: Tue, 17 Mar 2020 07:30:48 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Updates Sent from my iPhon e Begin forwarded message: From: "Fauci, Ant hony (NIH/NIAID) [E]" Date: March 17, 2020 at 7: 14:00 AM EDT To: Janet Tob ias Subject: RE: Updates Thanks, Janet. Please conti nue to work with Patty to make t his happen. Best regards, Tony From: Janet Tobias Date: Tuesday, March 17, 2020 7:00 AM To: Fauci, Anthony {NIH/ NIAID) [E] Subject: Updates -----~~ ------- (b)(6) Dear Tony: Quick updates , we have partnered with Story Syndicate/John Hoffman (who was in charge of First In Human and Alzheimer's and Obesity projects) on the film about your life . This will help us make sure that next year this film has maximum impact and we carry the message widely of "men serving men" and public health . NIH Communications head John Burklow, and the main office , knows and is very supportive and excited about the potential impact. They have worked super closely with John in the past. We are putting in the request for filming with the Vice President's office and we will work with Patty to figure out how to film your work and NIAID's work on COVID-19, which is important. But safety and NIH-000452 modelling appropriate behavior always first and foremost. Crews on my side tiny and all from Unseen Enemy. Thanks for everything, every day, and stay healthy, Janet PSThe Aids project, and the educational partnership with Howard Hughes Medical lnsitute continues in good state, just on hold as it should be. NIH-000453 Fauci, Anthony (NIH/NIAIO) [El Tue, 17 Mar 2020 03:04:31 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question about COVI0-19 Mechanism of Transmission From: Date: To: Subject: Please respond. From: EDWARD EITZEN (b)(6) Se nt: Sunday, March 8, 2020 3:10 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Subject: Question about COVI0-19 Mechanism of Transmission Hi Tony: Thank you for what you are doing for our country to try and limit the consequences of COVID-19. Many Americans are hanging on your every word, as they should be, and that includes me. A question about COVID-19 mechanism of spread: The reported reproductive number from China of about 2.6 indicates a likelihood of large droplet spread as the mode of transmiss ion from person to person . My question is - could there be a component of airborne spread (droplet nuclei) wi th this virus? If super spreaders exist with COVID-19, is airborne spread possible? Knowing the answer to th is question would help to inform decisions about PPEand Decontamination in settings such as Emergency Departments . If this is not already known definitively, could NIOSHand some key partners possibly study it in current quarantine settings? Thanks, Tony . God bless you and you r important work! Best, Ed Edward Eitzen, M.D., M.P.H. Senior Partner, Biodefense and Public Health Programs Martin-Blanck and Associates 2034 Eisenhower Avenue, Suite 270 Alexandria, VA 22314-4678 Office Phone: 719-548-9207 Cell Phone: (b)(6) Email: ------- (b) (6) NIH-000455 From: Fauci, Anthony (NIH/N IAID) [El Date: Tue, 17 Mar 2020 03:02:00 +0000 To: Lerner, Andrea (NIH/N IAID) [El FW: Flu statist ics Subject: Please respond for me. -----Original Message ----From: Candace Gunn --------Date: Sunday, March 8, 2020 10:53 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Flu statist ics (b-,-.. )(=6) -----~~ (b)( > Dear Dr. Fauci, First of all, thank you so much for the wonderful job you are doing regarding the infomrntionon the coronavirus. You were excellent with Chris Wallace! Js it possible to give facts on the FLU - number of people who have had it and how many have died - during the past month? I wonder if that might perhaps slow down the media frenzy. Many thanks for yow- consideration of my question. Best regards , Candace Gunn NIH-000456 Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 03:00:44 +0000 Anderson, Roy M RE: Lancet Commentary on COVID-19 From: Date: To: Subject: Roy: Thank you for your kind note. Very nice article! I hope that all is well with you . Best, Tony ------------------, (b) (6) > From: Anderson, Roy M Date: Saturday, March 7, 2020 5:27 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet Commentary on COVID-19 --------- .----..-.= (b)(6) Dear Tony, I thought the attached may be of interest to you . You have been doing a very good job in communicating the important issues around this epidem ic - well done. Kind regards, Roy Professor Sir Roy Anderson FRSFMedSci Director London Centre for Neglected Tropical Disease Research (LCNTDR) Department of Infect ious Disease Research, Faculty of Medicine Imperia l College London Praed Street London W2 lPG Te (b)(6) (b)(6) Assistant Project Manager Man ager LCNTDR (b)(6) ------.==============---- ~= (b) (6)1 -=================~~;(b) (6) NIH-000457 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 17 Mar 2020 02:59:48 +0000 To: Lerner, Andrea (NIH/NIAID) [El Subject: FW: Modeling of COVID-19 from Mike Levit Attachment s: 1.Analysis_of_Coronavirus-2O19_Data_Michael_Levitt-vl.pdf, 1.The_Corona_Chronologies. Part 11- Rest of the World. Michael_Lev itt,Stanford.pdf, 3O.The_Corona_Chronologies. Part I - China. Michael_Levitt,Stanford.pdf Please take a look and see what you thin k. From: Tabak, Lawrence (NIH/OD) [El Se nt: Friday, March 6, 2020 8 :46 PM To: Collins, Francis (NIH/OD) [El (b) (6) > (b)(6)> ------ == Cc: Lauer, Michael (NIH/OD) [El Subject: Modeling of COVID-19 from Mike Levit (b)(6); (b)( Fauci, Anthony (NIH/N IAID) [El > Francis, TonyMike Levitt (Nobel prize in Chemistry, 2013) sent the attached model ing of the COVID-19 epidemic to Mike Lauer. I don't know if this will prove useful but wanted to pass it along in case. He indicated that he was amazed to see how an Excel level analysis could allow him to predict the China epidemic would end as early at 2-Feb and get what he considers the best estimates for case fatality rat io . His first report from 2-Feb is attached as well as his most recent two-part report. Larry NIH-000458 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:54:15 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Community -Spread Covid-19 Contact Tracking Take a look and handle. From: John G. Boland Date: Thursday, March 5, 2020 10:00 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b)(6b (b)c-c (= > Subject: Community-Spread Covid-19 Contact Tracking Dear Dr. Fauci : Without success. for more than a week, I have tried to reach any techie CDC person about the problem of community-spread Covid-19 contact tracking. Though your workload is unimaginable. I thought you might personal ly know and could provide contact information of an appropriate CDC or NIH epidemio logist. ***Brief Summary of Concept***skip to End, if obvio us*** Had I bee n to a doctor or ER with a virulent disease, they would immediately have asked where I had been , with whom, and for what duration . With that information, epidem iolog ists can notify and test those contacts ... and their contacts ... before their symptoms are eviden ced. This manual contact tracking process is workload intensive, calendar -day wasting, data-poor, and inaccurate . "Location tracking" can provide the raw data needed to identify potential contacts automatically , early , and thorough ly, from information routinely collected by network providers. The location , at a date and time, of a vast number of anonymo us cell phones , over the preceding two weeks, wo uld be very useful for identifying the index case and subsequent contacts of an individual. As an illustration , the New York Times published , on 19 December 2019 . "Twelve Million Phones, One Dataset , Zero Privacy" about the commercial location tracking industry : https://www .nytimes.com/interactive/20 19/ 12/19/op inion/location-trackinq-cell-phone .html ***End of Summary*** Ignoring the techie and legal detai ls. can you suggest an appropriate contact, whi le Covid-19 infections in the United States are few? Your continuing dedication , candor , and data-driven focus are refreshing and very much appreciated, Dr. Fauci. Best , John G. Boland NIH-000459 (b)(6) .__ _____ ___ (24 hr, text or leave msg if no answer) NIH-000460 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:53:27 +0000 Tom Frieden RE: FYI I tried to call you this evening but got voice mail that said you were not accepting calls. Let us try to connect soon. -----Orig inal Message----From: Tom Frieden _________ (b ""~,.... c= - Date: Wednesday , March 4, 2020 l J: 12 AM To: Fauci, Anthony (NIH/NIAID) [E] ._______ Subje ct: FYI ------~~ (b _)_(6) _.> h tlps ://the h iiI.co m/po Iicy/ healthca re/ 4 8560 4- mee l-the- fede ra I- govern men ts-co ron a virus -exper t I know you don't read the papers but "super smru1:,super able to communicat e very cleru·ly, with a ve1y deep ethical commitment to doing the right thing" is exactly what f think , not just what I'm telling the media. All the best , Tom NIH-00046 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 02:48:31 +0000 Pardis Sabeti RE: Planning for a hearing on Global Health Security Team Pardis: Sorry that I d id not respond sooner. I am getting over 1500 emai ls per day and this one got lost in the pile . Anything that you can do to help would be welcome. Best, Tony From: Pardis Sabeti (b)(6) Se nt : Tuesday, March 3, 2020 9:31 PM To: Fauci, Anthony (NIH/NIAID) [E]-------~= (b)(6) Subject: Fwd: Planning for a hearing on Global Health Security Team Dear Tony, I hope that all is well given our current circumstances. I am sure you are very busy, so apologize for the intrusion, but wou ld love you r insight if you have a moment . I just had a very interesting talk today with Wendy Ginsberg on the House Committee on Oversight and Reform, w ith an opportunity to testify at a hearing next Wednesday {email attached) . While I am very excited for an opportunity to advocate for further funding and operational support for pandemic preparedness, I also recognize that th is forma t may not be the right one to do so. Moreover , I may not be the right person to do so, as I think you, Francis, or Eric Lander would do far better than me. I imagine they have already asked you to part icipate, and would just love any insight you might have as to whether I should consider do ing this, and if so, how I should proceed . I really only would want to do so if it is a place where I can help the larger infectious disease community and make a positive nonpolitical impact. Thanks so much fo r your consideration, Pardis ------------,,~ ------------ ---------- Forwarded message --------From: Ginsberg, Wendy Cb)C > Date: Mon, Mar 2, 2020 at 8:54 AM Subject: Planning for a hearing on Global Health Security Team To: (b)(6)> NIH-000462 Richard Preston pointed me in your dire ction, saying you wou ld be the right person to help me think thro ugh a potential hearing o n codifying the global health security team on the National Security Council. The hearing (as of right now in my mind) wou ld 1. Examine the lessons learned from the Ebola and ot her previous outbreaks about how federal government design and operations can fac ilitate or hinder global healt h and stemming pandemics; 2. Analyze how eliminating the global health security team has put us several steps behind where we need to be in figh ting coronavirus ; and 3. Argue for cod ifying th e team and its leader ship as part of th e larger national security apparatus and avoid kowtowing to outbreak fatigue. I'm hoping you might be w illing to speak w ith me about your expertise and thoughts in this area. I'm defin itely not the expert and I would love someone w ith your background to ensure I'm getting this story right - and that I have the right people at the witness stand to tell it . Would you have time to ta lk today or some time very soon? We are hoping to have this hearing next week . Yours, Wendy Wen dy Gins berg. Th.D. Staff Director House Committ ee on Oversight and Reform Su bcommittee on Government Opera tions (b)(6) Pardis Sabeti, MD, DPhil Professor, Harvard University & Harvard School of Public Health Broad Institute of MIT and Harvard Howard Hughes Med ical Institute -====~~---------------- Assistant : Phone: (b)(6) Website: www .sabet ilab.org (b)(6) NIH-000463 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 17 Mar 2020 01:46:44 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Wall Street Journal request Please decide if we can do this. From: Wi llick, Jason Date: Monday, March 16, 2020 9:44 PM ------------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: Wall Street Journal request ::;..,..-,= (b)(6 )1> Dear Dr. Fauci, My name is Jason Will ick wi th t he Wall Street Journa l. I was wondering if you would be willing to ta lk to me for the WSJweekend interview section on pandemics and the coronavirus - the US response but also the broader challenges from infectious disease. I know you are beyond busy, but I thought I'd ask. Let me know if this is a possibility and I can discuss more details. Jason NIH-000464 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:27:13 +0000 To: M ichael liu RE: Great advice from Chinese expert Subject: M ichael: Thank you for your note. We indeed have learned much from our Chinese colleagues . appreciate your bringing these issues to our attention. Best regards, Tony From: Michael liu (b)( > Date: Monday, Ma rch 16, 2020 8:14 PM ------~~ -------Subject: Great advice from Chinese expert To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Dear Dr. Fauci, Dr. Wenhong Zhang, has become very famous in China's war against COVID-19 because of his great excellence in anti-virus. Dr. Zhang is the D irector of the Infectious Disease Department of Huashan Hospita l in Shanghai. He is very good according to my observation all long. Another great doctor in China is Dr. Nanshan Zhong. According to Dr. Zhang's video at https ://www. thepaper.cn/newsDeta il forward 6537248 , COVID-19 can really be prevented with 3 key measures, i.e. to keep social distancing , wash hand s frequently and wear masks. I strongly suggest American people shoul d wear masks like Chinese, Soutl1 Korean people, etc., because even China ' s highest leader, Mr. Jinping Xi, wears masks. If it is difficul t for all the US p eople to do this now, I suggest working staff in airport s, supern1arkets and other pub lic places should wear masks firstly in order to avoid crossing infection. Further, Dr. Zhang said, if a p erson is still infected though he/she takes the above 3 measures carefully, the person must be infected by his/her family members . So I propose the concentrated isolation of mild confirmed cases should be considered as I advised yesterday. I strongly sugges t American government should learn precious experience of anti-COVID-19 from and cooperate with the mainland China, Taiwan, South Korea with an open mind. If you need any help to contact with Dr. Zhang , I will do what I can. I am very confident that the US government will lead American people to win the anti-COVID19 war by you and other great experts. Science, expertise and great learning are best medicines. God bless you! God bless America, China and the whole world ! Best regards, NIH-000465 Michael Liu (b)(6) ~f!J:A:Fauci, Anthony (NIH/NIAID) [E] [mailto: ~~la Ia.J:2020if3J:315B 13:28 (b)(6) IHlf!l:A: Jingm ing Liu (Michael) < ---------3:.B:Re: Great Advice on How to Avoid Family Spread of COVID-19 -------- Thank you for your note A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:26 PM, Jingming Liu (Michael) -------- (b)(6)> wrote : Dear Dr. Fauci, My name is Michael Liu. My family are living in now. I have been following spread of COVID-19 (Corona Vims) closely because such virns is very contagious and dangerous. (b)(6) If a person is mildly sick with COVID-19 , the CDC now suggests the person shou ld "stay home except to get medical care", i.e. home-isol ation, according to https ://www.cdc.gov /coronav irus/2019-ncov /downloads /slck-with- 2019-nCoV-fact- sheet.pdf However, the home isolation may result in family spread of COVID-19 in certain kinds of families, e.g., parents are infected but their kids are too young to take care of them, adults are infected but their parent s are too old and risky to look after them (if they live together) , an old husband /wife is infected but the spouse is too vulnerable to take care of him/her, etc. In such scenarios, the home isolation may increase family spread and even comm unity spread risks in the us. A great method to avoid home-isolation risks is the concentrated isolation, i.e. to isolate mild symptomatic people in a concentrated place instead of thefr homes. The concentrated isolation can avoid the above family spread risks, provide professional medical help to isolated people, reduce menta l pressure of other family members, etc., so that it can reduce community spread risks. Such method has been proved to be effective by China's war against COVID - 19. The conce ntrated place can be a hotel , university dorm building, etc., which should be easily managed for medica l surveillance. NIH-000466 The concentration isolation may be voluntarily chosen by relevant families at the beginning, and adjusted to apply subject to different conditions. Hope the above advice helpful! Best regards, Michael Liu NIH-000467 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 17 Mar 2020 00:23:16 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] Subject: RE:offer from Mark Zuckerberg I will write to or call Mark and tell him that I am interested in doing this. I will then tell him that you will get for him the name of the USG point of contact. I agree it shou ld be Bill Hall who could then turf to the White House Com ms if he wishes (bH > From: Billet, Courtney (NIH/NIAID) [E] Date: M onday, March 16, 2020 6:53 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Folkers, Greg (NIH/NIAID) [El (bH ; Conrad, Patricia (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [E) (bH >; Routh, Jennifer "'.'" (N - 1-H/-:-N-IA - l':"" D):--: [':"" El:-===::::::...-____;-= (b'"'"" )(= > -----~~ Subject: ASF: offer from Mark Zuckerberg Per email below, Mark Zuckerberg has extended a few offers to do videos with you that we would be happy to seek clearance on for you to do, if you are amenable. These would have the weight and impact of television - really, more so. Please advise if you want to do and we will seek clearance with VP office and work with Patty to sort out the logistics. But an even bigger deal is his offer (b)(4) The sooner we get that offer up the food-chain the better. I gave Bill Hall a heads-up about this opportunity and he is standing by to discuss this with HHS and WH comms, but I didn't want him to do anything without you being aware of the offer. Is it OK if I hand this aspect off to Bill to determine who the best point of contact would be so the Administration can take advantage of this offer, soonest? Do you plan to call MZ? His cell number is in his message below. From: Mark Zuckerberg (b)(6) Date: Sunday, March 15, 2020 12:18 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thanks and ideas ------ -------- ..-.-,= (b)(6J> Tony: I wanted to send a note of thanks for your leadership and everything you're doing to make our country's response to this outbreak as effect ive as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understan d you 're incredibly busy, so don't feel a need to reply unless these seem interest ing. This isn't public yet, but we 're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion peop le worldwide) with two goals: (1) NIH-000468 make sure people can get authoritative information from reliable sources and (2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live within the next 48 hours. As a central part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and political leaders. This could be done in a number of formats if you're open to it. Probably best would be recording a Q&A where you answer people's top questions , but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on the platform {100 million followers) to get authoritative information out as well. I'd love to have you do one of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel t he need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b) (6) . Thanks again for everything you're doing . Mark NIH-000469 From: Fauci, Anthony (NIH/N IAID) [E) Tue, 17 Mar 2020 00:22:45 +0000 To: Mark Zuckerberg Cc: Conrad, Patricia (NIH/NIAID) [E);Billet, Courtney (NIH/ NIAID) [E];Barasch, Kimberly (NIH/NIAID) [CJ Subject: RE:Thanksand ideas Date: Mark: Thank you for your kind note. I tried to cal l you, but got voice mai l. FYI, my cell phone number is (b)(6) Your idea and proposal sound te rr ific. I would be happy to do a video for your hub. We need to reach as many people as possible and convince them to take mitigation strateg ies seriously or th ings will get much , much worse. Also, your id ea about (b)(4 ) is vey exciting. I am copying my Special Assist ant, Patty Conrad. Her office numbe r is (b)(6) Cb)( • Please have your people contac t her to arrange for the video. I am also copy in g the Director of my Communications and Governmen t Relations gro up . She can put your people in contact with the best person who cou ld be the US Government poin t of con tact for (b)(4). ----- Best regards, Tony From: Mar k Zuckerberg (b)(6)> Date: Sunday, Marc h 15, 2020 12:18 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Thanks and ideas ------~~ -------- (b)(6)> Tony : I wanted to send a note of thanks for your leadership and everything you 're doing to make our country's response to this outbreak as effective as possible. I also wanted to share a few ideas of ways we could help you get your message out, but I understand you're incredibly busy, so don't feel a need to reply unless these seem interesting . This isn't public yet, but we're building a Coronavirus Information Hub that we're going to put at the top of Facebook for everyone (200+ million Americans, 2.5 billion people worldwide ) with two goals: (1) make sure people can get author itative information from reliable sources and {2) encourage people to practice social distance and give people ideas for doing this using internet tools. This will be live wit hin t he next 48 hours. As a centra l part of this hub, I think it would be useful to include a video from you because people trust and want to hear from experts rather than just a bunch of agencies and politi cal leaders. This could be done in a number of fo rmats if you're open to it . Probably best would be recording a Q&A where you answer people's top questions, but we'd be open to other fo rmats too. I'm also doing a series of livest reamed Q&As with health experts to try to use my large following on th e platform (100 million followers) to get authoritative information out as well. I'd love to have you do one NIH-000470 of these Q&As. This could be the video we put in the Coronavirus Hub or it could be a different thing that we distribute separately, but I think it could be effective as well. Again, I know you're incredibly busy, so don't feel the need to respond if this doesn't seem helpful. If it 's easy to talk live, give me a call anytime on my mobile phone: (b)( 6) Thanks again for everything you're doing. Mark NIH-00047 1 From: (b)(6) Date: Mon, 16 Mar 2020 19:40:27 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Coronavirus antibodies Please handle Begin forwarded message: From: Andrew Sprouse Date: March 16, 2020 at 4:00:44 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" ---------- Subject: Re: Coronavirus antibodies (b)(6) ------~~ --------- (b)(6J: If millennials are spread ing the corona virus sho uld we allow them to be tested with milder symptoms? Otherwise they have no idea they have it. On Mar 13, 2020 , at 5:27 AM , Fauci, Anthony (NIH/NIAID) [E] (b) (6)>wrote: It likely would On Ma r 13, 2020 , at 2:58 AM , Andrew Sprouse (b)(6J: How about human breast milk? Would it have the antibodies as well? Sent from my iPbone On Mar 12, 2020, at 7:53 PM, Andrew Sprouse (b) (6l> wrote: --------- Dr. Fauci, If China is taking patients and using the. plasma/ant ibodies from them to help cure other patients why couldn ' t we do that to heaittw people to give them immunity to the yip.I*? Andrew NIH-000472 NIH-000473 (bX5) -PCE NIH-000474 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO)[E) Mon, 16 Mar 2020 23:19:56 +0000 Monticone, Giulia RE:COVID19emergency Your arguments are solid. From: Monticone, Giulia (b)(6)> Date: Monday, March 16, 2020 7:00 PM To: Fauci,Anthony (NIH/NIAID) [E]-------=Subject: COVID19emergency (b)c(= -c > Dear Dr. Fauci, I am a postdoc researcher working at LSU health sciences center In New Orleans. I would like to communicate my concern about the COVID19 in the US. I am Italian and my partner is Chinese and we have been carefully following the COVID19 spread first in China and now in Italy and Europe. Based on my scientific and personal knowledge I am confident to say that the US is only few weeks ahead of What is happening in Italy now and this could on ly be stopped if strict measures will be taken in the enti re country as soon as possible. If you have the power , I ask you to please try to convince the government to apply such measures, even if this means to shut down the entire country for some weeks. I know that the economy and money interests are what often prevents to take such decision, but in this case we are ta lking about life and death and we cannot risk this high price. We have a very clear example of how severe the COVID19 can be if we do not act on t ime and th is is unfortunately my country at this time. We also have a good example, China, in which very aggressive measures have been applied and, despite some delay in their application at first, they now have reached a strong regression in the virus spread and they gradually can restart the country. China measures were to close every city borders, close working places and every non essent ial activity. They asked the population to stay at home and go out only for food and health emergencies. I think th is is what we should do in US too. A recent study from Italy in which they tested every person in one It alian city showed that the 50-70% of the peop le positive for the virus were asymptomat ic. This is such an impor tant information that tells us the only way to prevent the spread is to prevent the people from moving because we cannot really know who is caring the virus. Also, screening is important and should be ideally extended to everyone. http s:// www .repubblica.it /s alut e/ medicina-erice rca/ 2020/03/16/n ews/ coro navir us st udio ii 5075 dei casi a vo sono asintomat ici e molto contagiosi-251474302/ NIH-000475 My lab is based in New Orleans where the number of COVID19 cases is now growing fast. However, there is no sign from the university or my institute to close. We are working as usual with only some mild restrictions even if we have colleagues that are at home sick, or worse, that showed up at work coughing. The city mayor applied some restrictions but the people are still celebrating events on the street. Up to today we were acknowledged that we have a presumptive positive case in the building where we live. We are doing what we can as responsible individuals but tomorrow we will go to work again not knowing if we are spreading the virus. I thank you for reading this email and I hope my arguments are solid and accurate enough to encourage you to take action. Best wishes, Giulia NIH-000476 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:28:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: INTERVIEWQUOTE FOR ESPNFROM YOUR CALLWITH CARLODELRIOS From: Date: To: Subject: I did not say that they necessar ily should actually cancel the tournament, games. They could still play the tournament spectators in the gym. make a similar call i.e . not play the and have it televised without having many There is a big difference there. From: Conrad, Patricia (NIH/NIAID) [E) And I did not say that all sports should (b)(6) Date: Monday, March 16, 2020 3:22 PM ------- =---c-c= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: INTERVIEWQUOTE FOR ESPNFROM YOURCALLWITH CARLODELRIOS PLEASEADVISE Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ion al Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It sh ould not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Deat rick, Elizabeth (NIH/NIAID) [C) (b)(6)> Date: Monday, Ma rch 16, 2020 3:19 PM To: Conrad, Patricia {NIH/NIA ID) [E) -------~~ (b)(6)> Cc: NIAID COGCORE; NIAID Media Inqu iries ; NIAID FOG Subject: Interview request: ESPN ESPN Tisha Thompson (b)(6) Tisha.Thompson@esp n.com NIH-000477 Deadline: COBtoday Hi Patty, This reporter is writing about the NCAA's reaction COVID-19, and would like confirmation that the following actually occurred: Dr. Brian Hainline said two members of the NCAA's advisory panel, Dr. Colleen Kraft and Dr. Del Rio, spoke with Dr. Fauci, who said he would back the NCAA in its decision to cancel the tournament. That Dr. Fauci 11wholeheartedly" agreed and said to the NCAA reps, "Not only would he back us that this was the right thing to do ...he believed that all sports should make a similar call. 11 The reporter would like a quick call/confirmation this evening, before they publish the story. NIH-000478 From: Fauci,Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 21:17:44 +0000 Jon LaPook RE:Great news. Date: To: Subject: _______ --------------------- .., . Thanks again. (b)(6] Wonderful!! -----Origi11alMessage----From: Jon LaPook ,,;::;..----(b ~)~(6) => Date: Monday , March 16, 20204:13 PM ----- To: Fauci, Anthony (.,. NI.;..H _ IN _ I;_ A.;.. JD _ )::..::.. [E..:. ]....!::===== Subject: Great news . -=s:"=---------- ~= (b)(6) . Thanks again . Jonathan LaPook, M.D. Chief Medical Correspondent,CBS News Professor of Medicine NYU Langone Health Twitter @DrLaPook NIH-000479 Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 21:17:06 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Treatments that may be useful against the novel coronavirus From: Date: To: Subject: Please respond. From: PEAK (b) (6b Date: Monday, March 16, 2020 4:58 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Treatments that may be useful against the novel coronavirus Dear Dr. Fauci: I am a Cb)(6) assistant attorney general of the States of New York and Oregon. I have received some information that may be useful in dealing with the novel coronavirus, but I am not able to evaluate this information personally. It is in an a1iicle authored by a former asst. secretary of the US Treasury. I would like to make this information available to you for evaluation, and to that end I am copying it immediately below. Sincerely , Robert Roth Eugene, Oregon Treatments for Coronavirus That Have Worked in China Paul Craig Roberts • March 13, 2020 These are scientific papers showing effective treatments for coronavirus being used in China Hydrox ychloroqu ine https ://www.ncbi.nlm.nih.gov/pubmed/32 l 506 18 https://reader.elsevier.com/reader/sd/pii/S0924857920300820?token =92457EBC4 E7 5F28D02F3 l 1f610 OB2D48113£ 501DC04D49C824E6 FD819F77BE34A99 378 4AEAC0D l 15710BDB7BCC2175B5 These research papers show great antiviral promise for both HydroxychJoroquine and Chloroquine. The Chinese have started using them. So should we. The antiviral effects were originally disco vered in Europe during SARS, but then forgotten about as SARS was so aggressive it killed the host too quickly and died out. French ProfRaoult and others have helped the Chinese advising them to p roceed in this way and they had the good sense to trial it. Unlike vaccine s and costly new antiv irals, Hydroxychloroquine and Ch loroqu ine are generally safe, very well tested , cheap and readily available today. They could be a real game changer. Please publish and dissemina te. Please also re -refer to the Blaylock cytokine paper to emphasize the importance of vitamin C, D3 etc. Hydrox ychl oroquine and Chloroqu ine https :// www .ncbi.n lm .nih .gov/pubmed / 32 l 506 18 https ://reader.elsevier.corn/reader/sd/pi i/S09248 57920300820?token =92457EBC4E7 5F28D02F3 11F610 DB2D48113E50 1DC04D49C 824E6FD819F77BE34A9937B4AEAC0D 1157 10BDB7BC C2175B 5 https ://www.ncbi.nlm.nih .gov/pubmed/?term=chloroquine+coronavirus (Republi shed from PaulCraigRobe 1ts .org by permission of author or representative) NIH-000480 More at Roberts' homepage: https://www.paulcraigroberts.org/wpcontent/up loads/2020/03/ 14 2020 .010 12.pdf NIH-000481 From: Date: (b)(6) To: Cc: Subject: healthcare settings Mon, 16 Mar 2020 16:23:09 -0400 Luo, Yiming (NIH/NIAMS) [E) Kadlec, Robert (OS/ASPR/1O) Re: concerns regarding CDC recommendations for COVID-19 prevention in Yiming: Thanks for your note. I will forward your email to dr. Robert Kadlec who is in charge of the SNS. Best regards , To ny On Mar 16, 2020, at 2:53 PM , Luo, Yiming (NIH/NIAMS) [E] --------- (b)(6) > wrote: Dear Dr. Fauci, My name is Yiming and I am a clinical fe llow in rheumato logy at NIH/NIAMS. I have colleagues and friends working in community hospita ls fighting against COVID-19 and we are deeply concerned regarding the CDC inte rim recommendations for COVID-19 prevention in healthcare settings saying that "facemasks are an acceptable alternative w hen the supply chain of respirators cannot meet the demand" . Currently hospitals in New York City are asking their healthcare providers to wear surgical mask while t reating COVID19 COVID-19 is highly contagious in healthcare settings w ith a large proportion of healthcare professionals being infected reported in early literature [1]. A recent study suggested that asymptomatic patients can transmit SARS-CoV-2which puts potentially additional threats to healthcare providers [2]. Although surgical mask can effectively prevent droplet transm ission, whether and to what degree SARS-CoV-2can transmit through aerosol approach is still uncerta in. Studies with 2003 SARSvirus suggest a high level of concerns for aerosol transmission [3], and a recent unpublished study from MedRxiv revealed that SARS-CoV-2has similar aerosol stability compared to SARS[4). Healthcare professionals are our frontline force against the coronav irus emergency and we cannot afford even a slight probability of a large scale infect ions among healthcare workers due to insufficient personal protective equipment. We hope that accessing the Strategic National Stockpile (SNS)and any potential mass production program are actively being considered to protect, and ultimately, save lives for U.S. people. Sincerely, NIH-000482 Yiming Luo, MD [1] Wang et al, Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-lnfected Pneumonia in Wuhan, China. JAMA. 2020 Feb 7. Doi: 10.1001/jama.2020.1585. [2] Chang et al, Protecting health care workers from subclinical coronavirus infect ion, Lancet Respir Med . 2020 Mar;8(3):e13. doi: 10.1016/52213-2600(20)30066-7. [3] Jones et al, Aerosol transmission of infectious disease. J Occup Environ Med. 2015 May;57(5) :501-8. doi: 10.1097/JOM.0000000000000448. [4] Doremalen et al, Aerosol and surface stability of HCoV-19 (SARS-CoV-2)compared to SARS-CoV-1.doi: https ://doi.org/10 .1101/2020.03.09.20033217 (MedRxiv) NIH-000483 From: (b)(6) Date: Mo n, 16 Mar 2020 14:31:15 -0400 To: Redfield, Robert R. (CDC/OD);Deborah Birx Subject: Fwd: (b)(4) Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19 . This is a (b) (5) Begin forwarded me ssage: From: Jon LaPook (b) (6) Date: March 16, 2020 at 1:52:57 PM EDT To: "Fauci , Anthon y (NIH/NlAID) [E]" (b)( · (b) (4) Subject: ______ Algorithm for addressing people with mild upper respiratory symptoms in the age of Covid-19. ----------==-=--=-=- Hi Tony, Thank you so much for calling me this morning, and for your terrific help last night trying to think through the issue (b)(4), (b)(6) Given our discussion this morning, I think it would be very helpful if the task force on coronavirus came up wi t h a clear algorithm for addressing issues related to people having symptoms that could be from a cold, flu, or other virus - and not related to the virus that causes COVID-19. Let's say there's a hypothetical patient with some combination of sore throat, aches and pain, low grade fever in the 99's by mouth, and cough; there's no shortness of breath. let's say they are now proactively self-quarantined at home and are in the process of evaluation. Questions include : 1. Who, if any, of the person's contacts within the previous days should be contacted? 2. If it's only "close contacts" - those who were within 6 feet of the person for an extended period of time: a. What's t he definition of extended period of time? b. Does any physical touch ing- such as a hug or handshake - immediately mean there is significant contact? c. How far back from the onset of the person's illness do we need to check for "close contacts?" This gets to the issue of how long before symptoms begin can asymptomatic shedding occur. 3. If no Covid-19 test ing is available or the person has been told they are not sick enough for testing: how do we think about the potential risk to that person's contacts, for example, at home or work? NIH-000485 4 . If Covid-19 testing is available: before the result is back, what is t he advice for a corporation or other entity where the person being tested may have infected others through asymptomatic shedding of virus? Should the possible exposure, even if relatively "low risk", set off any protocol that deals with trying to minimize possible spread of the virus? Thanks! Jon Jonathan LaPook, M.D. Chief Medical Correspondent , CBSNews Professor of Medicine NYULangone Health Twitter @DrlaPook NIH-000486 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 14:23:32 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: coronavirus vaccine using cow pox-small pox example Niaid inquiries Begin forwarded message: (b)( From: nishit sawa l Date: March 16, 2020 at 1:39:58 PM EDT ------~~ To: "Fauci, Anthony (NIH/NIAID ) (E]" (b)(6J: , "Auchincloss , Hugh (NIH/NIAID ) (E]" (b)(6) , "Barasch, Kimberly (NIH/NIAID) [C]" _____ (b _>_ <, "Conrad, Patricia (NIH/NIAID) [E]" "Lerner, Andrea (NIH/NIAID) [E]" (bH6), "Mascola, John (NIH/YRC) [E]" (bH6J , "Graham , Barney (NIWVRC) [E]" (bH6)>, (b)(6) Subject: coronavirus vaccine using cow pox-small pox example hi sir, currently an effective vaccine for covid-19 appears 12-16 months away. in view of rampant spread of disease, we can use the cow pox-small pox idea to minimize the disease mortality. if general population at large was purpo sefu lly infected with human coronavirus stra ins which classically cause mild URTI's, the chances of them gett ing infected or more probably getting severe ly ill with covid-19 would be definitely reduced. we do not need to make a vaccine of these strains - classically they cause mild , selflimitin g URTI's. we have these resources and can do this in a ve1y short period. think over it - time to innovate like Edwa rd Jenn er did. rega rds, Dr Nish it sawa l. Consultant Neurologist Governmen t Medical Colleg e and Hosp ital . Chand igarh ,India NIH-000487 From: Date: (b)(6) To: Subject: Mon, 16 Mar 2020 13:45:28 -0400 Jethro Pen Re: Steven Hilton of Fox News' Covid19 Question to Dr Fauci et al. Stay tuned On Mar 16, 2020, at 1:40 PM, Jethro Pen -------- Cb)(6>\ >wrote : Dear Dr Fauci: Apo logies for further burdening your staff at this time of Covidl 9 crisis, by submitting this question. Fox News' Host Steven Hilton posed a ques tion to understanding of it - which my wife and I, question - is as follows: ou on his March 15th program: my (b)(6), believe to be a "good" "Given the relative safety of all but the elderly and those whose immune systems are compromised, and that they are far fewer than the rest of the population, why not quarantine only them?" Mr Hilton says he believes t here to be an answer, but it's not yet been given to the public. For what it's worth, I too believe there's an answer . I'm less certain that it's not been given . Below is the link to this matter on the Fox website. https: //www .fox news .com/opin ion/steve -hilton - on-coronavi rus -dr-fauci -offic ials-m ust answer -t he-big- quest ion-america ns-are-asking Thanks for such attention as this may be given. If in the present circumstances, that means none, I get it; nothing further is necessary or expected. Happy to t ry to provide anythi ng fu rt her which is needed or helpful. Sincerely, /s/ Jethro Pen NIH-000488 From: Date: (b)(6) Mon , 16 Mar 2020 13:36:16 -0400 To: Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) Fwd: March 26th hearing postponed Cc: Subject: Yeah! Begin fo1warded message: From: "Hallett, Adrienne (NIH/OD) [E]" ________ Cb _H_6) Date: March 16, 2020 at 1:23:40PM EDT ---------=-c-= ------- To: "Hodes , Richard (NIH/NIA) [E]" CbH6), "Volkow , Nora (NIH/N IDA) [E]" .------ CbH6), "Sharpless, Norman (NIH/NCI) [E]" (b)( 6) , "Fauci, Anthony (NIH/NIAID) [E]" CbH6)"Bianc hi, Diana (NIH/N ICHD ) [E]" CbH >, "Gordon, Joshua (NIH/NIMH) [E]" ________ Cb _>_<6), "Collins,Francis IH/OD) @,l~ ------~ Cb ~H=6>1 Cc: "Kelley, Melinda (NIH /NIA/ERP) [E]" Cb)C6) >, "Hobin, Jennifer (NIH/NIDA) [E]" CbH , "Holohan, MK (NIH/NC I) [E]" Cb> (6) , "Haskins , Melinda (NIH/NIA ID) [E]" CbH6) >, "Kaeser, Lisa (NIH/NICHD) [E]" Cb> C6J, "Ampofo, Phyllis (NIH/NIMH) [E]" CbH6)"Mitchell, Miche lle (NIH/OD) [E]" (b)(6) Subject: March 26th hearin g postponed 0MB is putting a ho ld on sending HHS witnesses to the Hill through the end of March . This will indefinitely postpone our budget hearing. Thanks for your patience, Adrienne Dear Agency Legislative Affairs Teams: Due to the full Administration mobil ization underway, we are placing a temporary hold on sending up government witnesses who are engaged in the coronavirus response. The Executive Branch needs all of its resources directly focused on executing its day-to-day respo nse to coronavirus. We will continue to p ractice "radical transparency" with Congress NIH-000490 and the American people, but participation in hearings cannot continue to divert resources from our response effort. This pause is effective immediately. It is intended to last for three weeks, through the end of March, though we will reevaluate if it needs to be extended at a later date . Importantly, as noted above, this does not only include witnesses for hearings that are explicitly focused on coronavirus, but also, to be determined on a case-by-case basis, witnesses and agencies who are playing vital roles on the Task Force or the broader Administration response, whether or not the hearing topic is coronavirus . Therefore, please do not accept hearing invitations from Congress for hearings through March if you believe they meet the above criteria . If you already have hearings confi rmed that you believe fits th is cr iteria, please notify us immed iately. You will likely have to postpone those hearings . Four corners leadersh ip offices have already been notified of this policy. Please reach out to 0MB if you have any questions, and we w ill be happy to work with you as we implement this policy. Thank you . NIH-000491 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:34:42 -0400 Billet, Courtney (NIH/NIAID) [E] Fwd: A SIMPLESTRATEGY FORPREVENTING CORONAVIRUS SPREAD Niai d inquiries Begin forwarded message: From: Walter T enge lsen (b)(6) Date: March 16, 2020 at 1:32:43 PM EDT -------~~ To: "Fauci , Anthony (NIH/N IAID ) [E]" CbH Subject: A SIMPLE STRATEGY FOR PREVENTING CORONA VIRUS SPREAD T o: Dr. Anthony S. Fauci , MD, Head of NIAID From: Walter Tengelsen , Chmn. of MACROSYSTEMS INST. First,, allow me to thank and congratulate you for telling the government, and the press, about our nation's unpreparedness for the coronavirus spread. But while we wa it for Big P harma to dev elop a vaccine for this disease, there is some thing that could be done NOW to prevent the spread of the virus ... and it wo u ldn't cost the gove rnment anything! Allow me to exp lain. Decades ago, when I was a designer in Aerospace , and took my drawing s up to the blueprint room for copies, I would always notice the 'aroma' of ammonia in the room. In quiring about the safety of thi s constant exposure by the blueprinting staff I was told that there are three groups of people who don't get co lds: 1) those work ing in salt mines, 2) those workin g in sewe rs, and 3) tho se working in blueprint rooms! A few decades later I was advised, by an MD, that the way to avoid colds is to keep sauce rs of household ammoniain my house rooms (and in the office rooms , if allowed), and that one would not even notice the smell after a few days. Since cold virus transmission is by aeroso l particles from the already -in fected, and the dilute ammonia fumes are able to NIH-000492 'inactivate' them, might these ammonia fumes be able to pro tect us against the coron aviru s? Admitted ly, too much ammonia gas can be very irritating (and even fatal, as in WW!), but evidently people seem to survive and thrive at the just-noticeab le gas levels being recommended here . If there is some potential lung damage from ammonia gas, that might be prevented by taking (freeze-dried) stinging nettles leaf, a widely recognized lung-cleaning supplement that is recommended by Naturopathic Doctors. But it would seem that the potentia l benefits of limiting the spread of the coronavirus in our entire population far outweighs the risks of lung damage . Since most homes already have bottles of anunonia (in their laundry area), this preventive strategy could be impl emented immediately, and would provide the public with the satisfaction of feeling they are doing 'their part' in combatting this pandemic ...and protecting themselves and their loved-ones. NOTE: I am NOT a medical doctor, but an electron ic systems enginee r and scientist (who takes systems engineering as a license to meddle in all things), but I was the first male family member in 4 generations who did NOT become a pham1acistor physician. I'm emailing my (old address) CV separately, but the email and ----~~ Cb)( still reach me as I'm cell phone number -(b)(6) _ , and then plan to____ ~= return to my new home in Cb)(6) (IF there's no travel res trictions in force)! I can be reached via ema il or cell phone to exp lain this preventive strategy further. Meanwhi le, good luck on all your efforts to contain this pandemic; the next four weeks or so will be critical! NIH-000493 (b)(6) From: Date: To: Subject: Mo n, 16 Mar 2020 13:33:40 -0400 Carlos del Rio Re: FYI... Thanks, Carlo s On Mar 16, 2020 , at 1:31 PM , Del Rio, Carlos --------- (bH6)>wrote: Dear super -st ar fr iends: I wanted to give you a heads up abou t a letter (attached} that myself as well as two AAAS Lesher fellows have been work ing on. Our goal is t o send t his with as many signatures as possible to the WH. Most of what we ask for is wha t you are already do ing or going to be doing but we are calling fo r e nforced social distancing mea sures, including closing or severely limiting all non-essential businessand schools nationwide. I hope t his is useful in our efforts. Sincere ly, Carlos del Rio, MD, FIDSA Distinguished Professo r fo r Emory Clinical and Academic Affa irs at Grady Professor of Medicine Executive Assoc iate Dean for Emory at Grady Emory University School of Medicine Professor of Globa l Health and Epidemiology Rollins School of Public Health Co-Director , Emor CFAR Tel : (b)(6) Tweeter: .___, (b """" )...,. (6) = Pro nouns: he/him/his This e-mail message (includ ing any attachments) is for the sole use of the intended recipient(s) and may contain confidentia l and privileged information . If the reader of this message is not the intended recipient. you are hereby notified that any dissemination. distribution or copying of this message (including any attachments) is strictly prohib ,ted If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-000494 From: (b)(6) Date: To: Subject: ill ness? Mon, 16 Mar 2020 13:19:42 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Can existing SARSvaccine be used to possibly limit severity of COVID-19 Please bandle Begin forwarded message: From: Benjamin Cintz (b) C Date: March 16, 2020 at 1:10:48 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" (b)(6). Subject: Can existing SARS vaccine be used to possibly limit severity of COVID-19 illness? . --------::-:--:-= Dr. Fauci, I have read that COVID-19 is close ly related to SARS. I am wondering if the existing SARS vaccine be used to possibly limit the sever ity of COVID19 illness in highly at-risk populations? Thanks, Ben Cintz Mobile: (b)(6) NIH-000495 From: Date: (b)(6) To: Subject: Attachments : Mon, 16 Mar 2020 13:12:18 -0400 Marston, Hilary (NIH/NIAID) [E] Fwd: Coronavirus Antidote Zn2+ Inhibits Coronavirus • 14 Mar ch 2020.pdf, ATT000Ol.htm People respond Begin fo1warded message: From: FH Mughal Cb> (6)> Date: March 16, 2020 at 1:05:20 PM EDT To: "Fauci , Anthony (NJH/NIAID) [E]" Subject: Fw: Coronavirus Anti dote -------=-c--c CbH6) I'm anx iou sly waiting for your respo nse. Kindly respond , the soonest - Thank you ----- Forwarded Message ----From: FH Mu hal ----~~ To: Cb)(> Date: Sunday, March 15, 2020 , 03:54:48 AM PDT Subject: Coronavirus Antidote Dear Dr Anthony Fauci and Hilary D. Marston Kindly enlighten me on the following points: Can the high temperature (30-35 degrees C) kill the virus? Can the heatwave ( 40-49 degrees C) kill the v irus? During last heatwave, t he te mperature in some cities of Pakistan was 47-49 degrees C. What is the antidote for coronavir us? In the fol low ing lin k, Pastor Jim Bakker is suggesting that the silver solution can kill the coronavirus within 12 hours. What are your views: Coronav irus 'Cu re ' Claims Get FTC Warn ing, So Maybe Don't Drink Silver NIH-000496 Coronavirus 'Cure' Claims Get FTC Warn ing, So Maybe Don't Drink Silver Thomas Brewster Science says drinking silver won't cure coronavirus, but companies offering the "cure" are trying to capitalize .. Coronavirus 'Cure' Claims Get FTC Warning, So Maybe Don't Drink Silver Th omas Brews t er Science says drinkin g silver wo n't cu re coro nav iru s, but co mp anies offe rin g th e "c ure" are t ry ing to capita lize ... In the attached paper, the authors say zinc can inactivate the virus. Your comments on silver and zinc, please. Could I kindly request for an early response, please. Thank you, Kind regards, NIH-000497 F H Mughal (Mr) Karachi, Pakistan NIH-000498 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 13:04:59 -0400 Billet, Courtney (NIH/NIAID) [E] Fw d: Hypothesis for reducing fata lities from Coronavirus NIAID inquiries Begin forwa rded message: From: Patrick Hackenbe rry Dat e: March 16, 2020 at 12:59:07 PM EDT To: "Fauci, Anthony (NIH/N lAID ) [E]" (b)(6) ------~~ (b)(6J: Subject: Hypothesis for reducing fatalities from Coronavirus Dear Dr. Fauci / to whom it may concern: I am not a medical doctor but I have an idea. I know you have every exper t on earth working on this virus. I am watching the attem pts to slow the transmission and "flatten the CUJve." What if we could reduce the fatality rate? Wouldn't that be huge and assis t in reducing the panic ? I am hearing that hosp itals are go ing to be short on respirators and that the virus attacks the lungs. My idea - might help people to breat h more efficien tly . Summary: Here is my idea: D octors need to uti lize methods that endurance athle tes have used in the past to increase their red blood cells in order to increase their body's blood-o xygen carr ying capacity. Further descript ion : Athletes like Lance Armstrong used blood doping and other ways to increase the ir Ery thropo ietin (EPO). This was called cheating in sports. Howeve r, the result s gave him an advan tage because his body could get mo re (V0-2 max) oxygen with a sing le breath compa red to others. T his helped Armstro ng to become more "supe r human ." I agree that this should be illegal in sports. However, I think it wou ld be great if a person was fighting for their life to be super human. NIH-000499 There are natural ways to increase your EPO and there are drugs to trick your body into producing more EPO. One of the best natural ways is high altitude training (think Boulder, CO and Kenya marathon runners). Also, the risks involved in increased red blood cell count obviously include stroke, blood clot, heart attack and many others. But I think that if monitored closely and as a last resort this method might help some people to survive this outbreak. Sincerely , Patrick Hackenberry (b)(6) From (b) (6) cell I have NO connections to the website(s) or companies below: Reference the article below from www.harnmemu trition.c om By: William Misner, Ph.D. From 1996 until his retirement in 2006, Dr. Bill worked full-time as Director of Research & Development at Hammer Nutrition. Among his many accomplishments, both academically and athletically , he is an AAMA Board Certified Alternative Medicine Practi tioner and the author of "What Should I Eat? A Food-Endowed Prescription For Well Being". - Dr Bill's Full Bio What is EPO? Erythropoietin (EPO ) is a naturally occurring hormone that stimulates the production of red blood cells (RBC). Erytbropoietin is a glycoprotein hormone produced in the kidneys, containing a 165-amino acids structure. Most erythropoietin is produced by the kidney's renal cortex, but some is also produced in the liver (mainly in the fetus), the brain and uterus. Why is it important? Erythropoietin production is stimulated by low oxygen levels in interst itial cells of the peritubular capillaries in the kidneys. Following its production in the kidneys , EPO travels to the bone marrow where it stimulates production ofred blood cells NIH-000500 (RBC's) [2]. EPO increases the body's blood-oxygen carrying capacity, but only up to a point. An ove rabundance may comprom ise health and hinder blood flow dyna mics with performance-limiting implications . In the absence ofEP O, only a few RBC's are formed by the bone marrow. Why are RBC's important? Red blood cells carry iron-rich hemoglobin for up to 120-days, then they die. Unless there is a continual supply of Iron, Vitamin B-12, Vitamin C and Folacin, anemia and reduced oxygen carry ing capac ity manifests in two ways: Low red blood cell count Malformed red blood cells. How can one increase their oxyge n carrying capacity? There is a distinct difference between unethical , harmfu l, EPO-blood doping methods and the safe nutr ition that effectively increases indiv idual oxygen-ca rrying capac ity. Once can improve their hea lth and oxygen carry ing capac ity similar to EPO without compromising the athlete's health or integrity. EPO levels up to 48% safely improve performance in males, however beyond this level, the risk of compro mised health increases . Look to dietary suggestions below regarding vitam ins, minera ls, proteins, and avoid ing anem ia to ensure oxygen carry ing capacity. Can excess EPO can be lethal? Yes. The margin between effective and letha l quantities of EPO is very narrow. EPO use can be LETHAL. Many athletes seeking to derive its performance -enhancing effects have died from incorrec tly-administered EPO . Inappropriate use of exogeno us EPO can cause elevated hematoc rit levels (i.e. thickened blood that is difficult to pump). Elevated EPO increases the risk of heart attack due to the increase in hematocrit. Choosing sustainable, healthy choices is preferred. Exogenous EPO is totally cleared from the urine with in 48 hours of its administration and is cleared from the blood within 72 hours of its administration but its physiologica l effects prevai l for severa l months). [3) A look at EPO's comp lex pathway further illustrates a complex physiologica l process below, see PATHWAYS[4]. Resea rch followed over 7,000 middle-aged men for more than 12 years, and discovered that the risk of diabetes increases proportionate to hematocrit increase.[19) [20). Men with hematocrits above 48 percent have a 400% increased risk of non-insul in-depe ndent-diabe tes mellitus. The upper recom mended levels for a female is slightly lower at 45%. This nutritional intervent ion parallels exerc ise intens itys effect for increasing EPO. Nutr itional and training interventions for reso lving low EPO levels during iron NIH-000501 supplementation (only prescribed by a physician who should monitored progress) shou ld not be permitted above a refere nce ra nge of 48% in males and 45% in fema les. Similar resea rch confirms this repo rt. [21] [22] [23] Does exercise intensity increase EPO? It's comp licated. Roberts & Smit h measured the effects of exerc ise-ind uced hypoxia on the physiological production of erythropoie tin. Twenty athletes exercised for 3 min at 106-112% maximal oxygen consumption. The fitness of these athletes prov ides a physiological env ironment for increasing EPO naturally from short 3minute all-out intervals . Estimated oxyhemoglobin saturat ion was measured by reflective probe pulse oximetry (Nellcor N200) and was validated against arterial oxyhemoglobin saturation by CO-oximetry in eight athletes. Serum erythropoietin concentrat ions, as mea sured using the IN CST AR Epo-T rac radio immunoassay, increased significant ly by 19-37% at 24 hour s post-exercise in 11 participants who also had an arterial oxyhemoglobin saturation< or= 91 %. Decreased ferritin levels and increased reticulocyte coun ts were observed at 96 hours post-exercise. However , no significant changes in EPO levels were observed in nine non-desaturating athletes and eight non-exe rcise contro ls. Good agreement was shown between arterial oxyhemoglobin saturation and percent estimated oxyhaemoglobin saturation (limits of agreement= -3.9 to 3.7. They concluded that a shor t 3 minutes supramax imal exerc ise pe riod cou ld induce both hypoxem ia and increased erythropo iet in levels in we ll-train ed indi vid uals . The dec line of arteria l hypoxemia levels below 91 % during exercise appears to be necessary for the exercise -induced elevation of serum erythropoietin levels. Furthermore, reflective probe pulse oxim etry was found to be a valid predic tor of percent arter ial oxyhemoglob in saturatio n during supramaxima l exercise when percent estimated oxyhemog lob in satura tion> or= 86%.[9] What naturally occur ing, nutritional building block s aid in EPO production? Protein adequacy is a factor in erythropoietin (EPO) production . Inadequate protein nutrition can reduce the EPO produced. The erythroid response to Erythropoietin (EPO) is highly dependent on dietary protein adeq uacy and qua lity . The mouse spleen is an erythropo ietic organ, whic h contains an EPO-responsive cell population that can be easily amplified by administration of the hormone. Researchers determined the effect of a protein-free diet offered freely to mice up to two days afte r injection of r-Hu EPO (l000mU /200 ul) on the response of the above pop ul ation. Sp lenic ce ll suspen sions from control and experimental mice were prepared in microwells containing 400 mU r-Hu EPO and appropriate medium. The response to EPO was evaluated in terms of 3H-thymidine uptake. The results obta ined indicate that acute ly induced protei n restr iction suppressed the response of the EPO-responsive splenic ce ll population to EPO when it was imposed on mice immediately after hormone injection, and suggest the appearance of deficient rates of differentiation of erythropoietic units by protein restriction .[ 11] Adequate dietary protein intake is 1.4-1.7 grams /kilogram body weight per day for an end urance NIH-000502 athlete. What other nutritional elements and processes affect the natural product ion of EPO and the body's oxygen carrying capacity? Dietary Iron. To ensure oxygen carry ing capacity, one shou ld take the recommended dai ly va lue of iron. Food sources of iron are red meat, liver, and egg yolks. Most flour , bread, and cereals are iron-fortified. If the diet continues to be iron-deficient , only a physician should prescribe and supervise iron supplementation. Ca lories . Calor ies are needed for EPO production . Calorie sufficie ncy (in spite of exercise expense) is required for optimal EPO-r elease. If training is causing weight loss, then EPO loss may be occurring. In order to test the hypo thesis that the early cessat ion of erythropoi et in (Ep) production during hypobaric hypoxia is induc ed by lowered food intake, researchers compa red the p lasma Ep titer of rats after expos ure to continuous hypoxia (42.6 kPa = 7000 m altitud e) for 4 days in fed or fasted rats after exposure to discontinuous hypoxia. They found that plasma Ep was rather low afte r 4 days of cont in uous hypoxia . Their findings showed that fast ing lowers the EPO- response to hypoxia in normal rats [12]. Hormone and Glucose. EPO production also has hormonal-dependant roots complex ly related to glucose metabolism, and calorie adequacy . The effect of Thyroid-T3 rep lacement and glucose supplemen tation on erythropo ietin production was investigated in fasted hypoxic rats. It was found that 48 hr of fasting significantly reduced the circulating levels of thyroid hormones and the prod uction of renal and extra renal erythropo iet in in response to hypoxia . These effects of fast ing were comp lete ly abo lished when the an imals had free access to 25% g lucose solution as drinking water , despite their Lackof protein intake. Replacement doses of T3 (0.5 micrograms / 100 gm per day) restored erythropoietin production in the fasted anima ls but a lso increased the response of the fed contro ls. To avoid the effec t of endoge nous T3, the experiments were repeated in thyroidectomized rats. EPO prod uction in athyroid rats was found to be markedly decreased , with values equivalent to those found in nonnal fasted animals, and were not affected by fasting or glucose supp lementa tion. Replaceme nt doses of T3 increased EPO product ion in all three gro ups, but the fasted anima ls needed five t imes as much T3 to obta in a response similar to that observed in the fed group. Glucose suppl ementation enhanced the effect ofT3 in the fasted animals but did not completely restore them. These results indicate that ca loric deprivat ion is primarily respons ible for the decreased EPO production induced by fasting and that this effec t is proba bly mediated by both a decreased level of T3 and a decreased responsiveness to it.[13] A calorie deficit therefore requires 500% more Thyroid Hormone (T3) to maintain EPO leve ls. Th is is a good reason for monitoring ca lorie intake during high h·aining ca lori e expense. Iron abso rbtion . Dietary intervent ions sign ifican tly advance nonheme iron abso rptio n rate during EPO production. It is very important to include foods to NIH-000503 enhance nonheme iron absorption, especially when an exercise-induced iron loss is high or when no heme iron is consumed, such as in a vegetarian diet. Absorption of heme iron is very efficient; the presence of red meat increases absorption of nonheme iron +400%. Only 1-7% of the nonheme iron in vegetable staples in rice, maize, black beans , soybeans, and wheat are absorbed consumed alone. Vitamin C improves the rate of absorption of nonheme iron from red meats. Diets that include a minimum of 5 serving s of fruits and vegetables daily provide adequate vitamin C to boost nonheme iron absorption. Calcium , polyphenols , tannins from tea, and phytates (a component of plant foods), rice, and grains inhibit the absorption of nonheme iron. Some of the protein found in soybeans inhibit s nonheme iron absorpt ion. Most hea lthy individuals maintain normal iron stores when the diet provides a wide variety of foods. However, if the diet contains large amounts of oxalates and phytates from dark green leafy vegeta bles and whole cerea l grains the abso rption of iron decreases due to binding with iron in the gut. High absorption of heme iron is further advanced by foods containing vitamin C in an acid environment found of the stomach. The recommended for daily iron intake is between 10-18 milligrams for adult males and postmenopausal females. Most endurance athletes consume too much iron. Iron is added to breads, cereals, and most packaged foods. From a computer-generated dietary analysis on 16 endurance athletes and 9 nonathletes, iron intake from their reported food intake was assessed. The results of this data is as follows: GROUP PERCENT DAILY IRON (RD I/RDA) MALE ENDURANCE ATHLETE 279% FEMALE ENDURANCE ATHLETE 193% MALE SEDENTARY 158% FEMALE SEDENTARY 115% What are some food combinations that incr ease the absortion of iron? NIH-000504 How foods are combined may affect iron absorption rate. Excess iron overdose is unhealthy and should be avoided. Common side effects of acute iron ove rload are gastro-intes tinal pain, constipation, nausea, and heartbwn. Excess iron levels may generate a continuous low-grade infection. Foods are the best source of iron. The best food source of iron is liver and red meats. These foods contain heme iron, which is better absorbed than non-heme iron. No n-heme iron can be found in dark green, leafy vegeta bles (spinach, chard and kale) and whole cereal gra ins (bran and whole wheat bread). Include dark green, leafy vegetables and who le cerea l grains in the daily diet. Oxalates and phytates found in dark green leafy vegetables and whole cereal gra ins decrease the absorption of iron because they bind with iron in the gash·ointestina l tract. Iron fo11ified cereals increase iron from the diet. Anem ia may develop on a meat-free diet and/or if the iron store or intake is low. Red meat contai ns arachidonic acid, an EPO-p recu rsor nutrient, but it also conta ins high leve ls of saturated fats and chol esterol sugges ting a little (now and then) is good but too much will harmfully compromise cardiovascular lipid levels. Adding iron to the diet in supplementa l form is not reconunended except under the superv isio n of a physician who is monitoring blood serum leve ls for a spec ific outcome. It has been shown that eating red meat 1-2 per week may contribute to providing substrates known to regenerate EPO as shown in anima l research . The ability of Arachidonic Acid (AA), the bisenoic pro staglandin precursor to stimulate erythropoi esis and Eiythropoietin (EP) Production in exhypox ic polycythemic mice and the programmed isola ted perfused canine kidney was found to stimul ate erythropoi esis when adminis tered to exhypoxic polycythernic mice in the lowest dose tested (50 microgram/kg i.p.). Endogenous ly synthesized prostaglandins, their intermediates and/or other products of AA metabo lism, such as prostacyclin and prostaglandins pl ay an importan t role in the control EPO production.[14] Hematocrit levels are restored through the supplying dietary or supplementa l specific substrates to support the body's na tural EPO-produ cing mechanisms during endurance exercise stress . SUBSTRATES THAT ASSIST EPO METABOLISM[l5] Acidophilu s - 15-30 Billion Count Probiotics Coenzyme QlO - 150-300 mg daily Garlic - 2 cloves or 2 capsules up to 3 x day Kelp - 100-225 micrograms V itamin B6 - 50-100 mg Vitamin B12 - 200-1 ,000 mcg Folic Acid - 800 mcg Prot eolytic enzymes - Bromelain & Papain Selenium - 200 mcg Vitamin A - 15,000 IU daily or Beta Caro tene - 25,000 IU daily Vitamin B Compl ex - 50-100 mg Vitamin C plus Biofla vonoids - 1-3 grams (divided dose) Vitamin E - 400 IU da ily NIH-000505 Copper- 2 mg Zinc 40 mg daily ---->(Do not take zinc in amounts over 40 mg daily as it may interfere with metabolism of iron and copper) More Dietary Recommendations There is a method to improv e iron uptake in the absence of oxalate or phytate rich foods previously men tioned above. If hematocrit, hemog lobin, or fe1ritin blood lab measures are low, the athlete may add 1-gram of vitamin C to a 3-4 ounce lean cut of red meat cooked in an iron skillet one to two times each week. A complete dietary protoco l for cance r patients going through chemotherapy and radiation was published and is applicable to over-trained endurance athletes who present low hematocrit levels. [ 16] Conclusion In normal adults, the kidneys produce EPO, which initiates approximately 90% of natural erythropoietin production. Tissue oxygenation exposure regulates the production of erythropoietin . Less oxygen saturat ion in the air we inhale (eithe r by altitude or hypoxic interval training) stimulates the kidneys to activate the chemica l messengers to instruct the bone marrow to increase the production of EPO to resolve the lack of oxygen exposure. Hypoxia or Anemi a stimulates the kidney production of erythropoietin to increase production red blood cells . EPO released from the kidneys increases the rate of red blood cell division and differentiation of specific cells in the bone marrow. Dietary deficiency of spec ific foods and micronutrients, horm one imbalance, and lack of specific hypoxic training stress inhibit the endogenous (natural) production of EPO. Additionally, nutritional imbalance from caloric restriction (or exercise related expense), dehydrat ion, fluid intoxication, excess calcium, excess inositol, excess oxalates foods, excess phytic acid from cereal gra ins, or a lack of hypoxic interval trainin g all inhibit the natural production of EPO also. [17] [18], Manipulating diet for protein and total calor ie adequacy, monitoring hydration, using supplements, timing food combinations, adding weekly hypoxic exercise followed by easy or rest days all increases the release of natural EPO for healthy maximal oxygen carrying capacity. Plus, there are many ways to use diet and wellness to ensu re that the body's production of red blood cells is sound and that their oxygen carrying capacity is functioning. [1] Director of Research & Product Development for HAMMER NUTRITION LTD. 1-800-336-1977, Whitefish, Montana. [2] Courtesy of From Wikipedia , the free encyclopedia@: http ://en.wikipedia.org/wiki/Ma in Page NIH-000506 [3] In-Tele-Health 2002 (from Hyperhealth Pro CD-ROM) [4] Cou rtesy ofBioca 1ta@ http://www .biocarta .com/pa thfiles /h eponfkb Pathway.asp [5] CLINICA L PHARMACOLOGY OF PROCRIT @: http ://www .procrit.com/profo nly/neph rology/wha t is procrit/clinical pharmaco logy .html [6] Fisher JW . Pharmacologic modu lation of erythropoietin production. Ann u Rev Pharmacol Toxico l. 1988;28:10 1-22. [7] Plasmapheresis is the process of separating certain cells from the plasma in the blood by a machine; only the cells are returned to the person. Plasmapheresis can be used to remove excess antibodies from the blood. [8] Roberts D, Smith DJ, Donnelly S, Simard S., Plasma-volume contrac tion and exercise-induced hypoxaemia mod ulate e1ythropoiet in production in healthy human s. Clin Sci (Lond). 2000 Jan ;98( 1):39-45. [9] Roberts D, Smith DJ. Erythropo ietin concentration and arterial haemoglobin saturation with supramaxima l exerc ise. J Sports Sci. 1999 Jun; 17(6):485-93. [10] Brun JF, Bouchahda C, Chaze D, Benhaddad AA, Mica llef JP, Mercier J. The paradox of hematocrit in exercise physiology: which is the "normal" range from a hemorheologist's viewpoint? Clin Hemorheol Microcir c. 2000;22(4):287-303. [11] Depressed respon se of the erythropoietin-responsive splenic cell population to erythropoietin in acutely protein restricted mice. In Vivo. 1995 Jan-Feb ;9( 1):71-3. [12] Jelkmann W, Kurtz A, Bauer C., Effects of fasting on the hypoxia -induced erythr opoi etin production in rats. Pflugers Arch. 1983 Feb;396(2): 174-5. [13] Caro J, Silver R, Ers lev AJ, Miller OP, Birgegard G., Eryt hropoietin produ ction in fasted rats. Effects of thyroid hormones and glucose supplementat ion. J Lab Clin Med. 1981 Dec ;98(6):860-8. [14] Fo ley JE, Gros s DM, Ne lson PK , Fishe r JW. The effects of arac hidonic acid on erythropoietin produc tion in exhypox ic polycythemic mice and the isolated perfused canine kidney. J Pharmacol Exp Ther. 1978 Nov;207(2):402 -9. [ 15] As with any supplement , always confirm with your phys ician as to the appropr iate level and selection prior to use. [ 16] Nutritional Interventions for Reducin g the Negat ive Side Effec ts of Chemothera py, Bill Misner, Ph.D. http ://www .cancure.org/Chemo support.htm NIH-000507 [17] Oxala te-rich foods are: Spinach , Cerea ls, Green Beans (steamed), Potato (raw), Pean ut Butter, Tea (brewed), Cele ry, Choco late, Rav ioli, and White Bread. [18] Phytate-rich foods are Grains , Corn, Oats , Rice Bran , Wheat Bran, Legumes , Peanuts , Soybeans, and Seeds . [19] Catalano C, Muscelli E, Natali A, Mazzoni A, Masoni A, Bernardini B, Seghieri G, Ferrannini E. Reciprocal association between insulin sensitivity and the haematocr it in man. Eur J Clin Invest. 1997 Jul;27(7):634 -7. [20] Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk ofNIDDM. Diabetes. 1996 May;45(5):576-9. [21] Sit D, Kad iroglu AK, Yilmaz ME, Kara TI-I,Isikog lu B. The prevalence of insulin resistance and its relationship between anemia, secondary hyperparathyroidism , inflammation , and cardiac parame ters in chronic hemodialysis patients. Ren Fa il. 2005;27( 4):403- 7. [22] Evrengul H, Dursunoglu D, Kaftan A, Kilicaslan F, Tanriverdi H, Kilic M. Relation of insulin resistance and left ventricular function and structure in non diabet ic pat ients with esse ntial hype rtension . Acta Cardiol. 2005 Apr;60(2) : 191-8. [23] Amoah AG, Schuster DP, Gaillard T, Osei K. Insulin resistance, beta cell function and cardiovascular risk factors in Ghanaians with varying degrees of glucose tolerance. Ethn Dis. 2002 Fa11;12(4):S3-10-7. NIH-000508 From: Date: (b)(6) To: Subject: Mon , 16 Mar 2020 13:00:10 -0400 Lerne r, Andrea (NIH/NI AID) [E) Fwd: natu ral course of the coronavi rus pandem ic Please handle B egin forwa rded mess age : From: Martin Gelbaum Cb)< > Date: Mar ch 16, 2020 at 12:52:24 PM EDT -----~~ To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6J Cc: M artin Gelbau m Cb )( Subject: natural course of the coronavirus pandemic Reply-To: Cb)(6) 2020-03-16 Dear Dr. Fauci, Thank you very much for courageous and tireless efforts to defeat the coronavirus pandemic . One of the statements attributed to you puzzled me. Th e articl e Dr. Anthony Fauci Says He Would Like a 'Dramatic' Reduction of Personal Interactions at Social Gatherings to Fight Coronavirus, by Donica Phifer, newsweek.com March 15, 2020 02:20 PM https ://www .newswee k.com/dr-ant hony-fauci-savs-he-would-like-dramaticreduction-personal-interactions-socia l-14924 1O" quotes you as saying , "I've said many times if you just leave it alone and left the virus to its own devices then it'll go way up and it'll come down naturally over a period of several weeks ," Fauci said. "Unfortunately for our colleagues in Italy, in France, and certainly in China, that's what happened ." NIH-000509 Question: Is the implication that the virus would have stopped spreading rapidly in China even if their government had not instituted drastic measures to curtail the epidemic? Put another way: Is it not correct that the drastic measures implemented by the Chinese government were very helpful in halting the spread of the virus in China? From yet another angle: Is it correct that the public health measures adopted in South Korea and Taiwan have proved very effective in controlling the spread of the epidemic? Thank you very much again for your hard work, Martin NIH-000510 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:58:37 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: thank you Please handle Begin forwarded message: From: Robyn Cotter (b)(6) Date: March 16, 2020 at 12:53:29 PM EDT -------~~ To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: thank you --------- (b)(6) Hello Dr. Fauci, --------- (b)(6) I live a very normal life in a Tennes see suburb. We have a 1ways kept a modest supply of important sw-vival items in our home, so we are prepared , not panicked. We are carefully following the information and facts regarcling the Coronavirus and taking the appropriate safety suggestions. The reason for my email toda y is to thank you for your expertise. You must be exhausted from the stress. No t to mention having to continually repeat yourself... and stretch your political diplomacy to the breaking point while walking the fine line between stating facts and debunking myth s (or outright lies) . Please know that my family and I thank you for your continued professionalism, swift communication of facts and overall leadersh ip while we ride this rollercoas ter with our neighbor s and the rest of the world. Sincerely, Robyn Cotter NIH-000511 From: (b)(6) Date: To: Mo n, 16 Mar 2020 12:56:53 -0400 Conrad, Patricia (NIH/NIAID) [E) Subject: Fwd: [EXTERNAL] Re: Fox News Request for Dr. Fauci FYI Begin forwarded message: From: "Koerber, Ashley" Date: March 16, 2020 at 12:56:25 PM EDT --------~~ To: "Conrad , Patricia (NIH/NIAID) [E]" (b)( (b) < , "Routh , Cc: "Deatrick , Elizabe th (NIHINIAID) [CJ" (b) (6) , "Op linger, Ann e Jenni fer (NIH/NIA ID) [E]" (b)( , "Fauci, Anthony (NIH/NIA ID) [E]" (NIH/N IAID) [E]" -------- (b)(6) ...----------- Subject: Re: [EXTERNAL] Re: Fox News Request for Dr. Fauci Hi Patricia, Would Dr. Fauci be available to join Bret Baier in th e 6pm hour one night this week? I underst and he is very busy , but we wou ld accommodate him any night tba t be is avai lable. P lease get back to me when you can - thanks! -Ashley As hley Koerber Moir Booking Producer Special Report wl Br et Baier Fox News Channel- DC Bureau (b)(6) ( cell) Sent from my iPhone ----- On Mar 13, 2020, at 15:32, Conrad, Patricia (N IH/NIA ID) [E] (b) (6)>w rote : I am sorry- we cannot make this work . Apologies . Patricia L. Conrad NIH-000512 Public Health Analyst and Special Assistant to the Director National Institute of Alle rg y and Infect ious Diseases The National Inst itutes of Hea lth 31 Center Driv e, M SC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 30 1-496-4409 fax Disclaime r: The information in this e-ma il and any of its attachmen ts is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and de lete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf or the NIAID by one of its representatives. From: Baier, Bret Date: Friday, March 13, 2020 3:30 PM To: Koerber, Ashley ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6b Cc: Deatrick, Elizabeth (NIH/NIAID) [C] (b)(6)>; Routh, _.;...._....;..;...;.::::==c~=---:-:-:------:--(b)( ; Oplinger , Anne (b)(6) ; Fauci, Anthony (NIH/NIAID) [E] _ _..:._.:.....:.======~~-- Jennifer (NIH/NIAID) [E] (NIH/NI A ID) [E] (b)(6) Subject: RE: [EXTERNAL] Re: Fox News Request for Or. Fauci Thank you for considering . I know Dr. Fauci has been a lot... and will be this weekend ... but tonight to wrap th e week .. afte r the national emergency declaration ... We'd love to have him Bret Bret Baier Chief Political Anchor, Fox News Channel Anchor &Executive Editor "Special Report with Bret Baier" From: Koerber , Ashley Date: Friday, March 13, 2020 3:27 PM To: 'Conrad, Patricia (NIH/NIAID) [E]' Cc: Deatrick, Elizabeth (NIH/NIAID) [C] -------~~ (b)(6) (b)(6J>; Routh, .,....:_ __ .:...:.......:...!:=~=~-----Jennifer (NIH/N _IA_I_ D:.. ) [:E ....::.. ] ...====~~-::"' (b""".' )(_ >; Oplinger, Anne (N IH/ NIAID) [E] (b)(6b; NIH-000513 Baier, Bret Subject: RE: [EXTERNAL]Re: Fox News Request for Dr. Fauci Hi Patricia, I know this is last minute, but any chance Dr. Fauci can join us in the 6pm hour tonight? Looping in Bret as well. Please get back to us when you can - thanks! -Ashley Sorry - w ill not work. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Insti tute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fa x Disclaime r: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please infor m the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Koerber, Ashley Date: Thursday, March 12, 2020 8:55 AM To: Conrad, Patricia (NIH/NIA ID) [E)_______ Cc: Deatrick, Elizabeth (NIH/NIA ID) [C] Jennifer {NIH/NIAID) [E] _,(,b.., ~=(6) "' > (b)(6) Routh, -""""""""'":"=:--------(b)( >; Oplinger, Anne NIH-0005 14 (b)( > (NIH/NIAID) [E] Subject: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci ----------- Hi Patricia, Would Dr. Fauci be availab le to join Bret tonight in the 6pm hour? Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)( cell) Sent from my iPhone _________ ..... On Mar 10, 2020, at 11:20, Conrad, Patricia (NIH/NIAID) [E] Cb)(6)>wrote: Oh - tonight is even worse . I don't think it will work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infect ious Diseases The National Inst itutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-mai l and any of its attachments is confidential and may contain sensitive informat ion. It should not be used by anyone who is not the original intended recipient. If yo u have received this e-mail in error please inform the sender and de lete it from your mailbox or any other sto rage devices. National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its represe ntatives. From: Koerber , Ashley Date: Tuesday, March 10, 2020 11:08 AM ---------=-=-=- To: Conrad, Patricia (NIH/NIAID) [E] Cc: Deatr ick, Elizabeth (NIH/NIAID) [C] NIH-000515 (b)(6) Cb)( >; Routh, Jennifer (NIH/NIAID) [E] --=======~5'""~ Opl inger , Anne (NIH/NIAID) [E] (b)(6)>; (b~ )( ~ > :========~ Subje ct: Re: [EXTERNAL]Re: Fox News Request for Dr. Fauci@ 6pm on Tuesday I'm asking about tonight. Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6)(cell) Sent from my iPhone On Mar 10, 2020, at 10:51, Conrad , Patr icia (NIH/NIAID) [El CbH6>>wrote: Hi Ashley I don't think we can make this work tomorrow. If anything changes will let you know. Sent from my iPhone On Mar 10, 2020, at 10:49 AM, Koerber, Ashley wro te: Hey Patricia , Just checking on this! Ashley Koerber Moir Booking Producer Special Report w/ Bret Baier Fox News Channel - DC Bureau (b)(6) ( cell) ------ Sent from my iPhone On Mar 9, 2020, at 15:11, Koerber, Ashley NIH-0005 16 wrote : Our special is actually 6-8pm tomorrow, so we could do either 6pm hour or 7pm hour. From: Koerber, Ashley Se nt: Monday, March 9, 2020 11:48 AM To: Patricia Conrad (b)(6) - Subject: Fox News Request for Dr. Fauci@ 6pm on Tuesday Hey Patricia, Wou ld Dr. Fauci be available to join us in the 6pm hour tomorrow (Tuesday) to discuss the latest with COVID-19 from any of the NIH studios? Bret Baier and Martha Maccallum are co- ancho ring from New York . Please get b ack to me when you can thanks! -Ash ley Ashley Koerber Moir NIH-0005 17 Booking Producer Special Report w/ Bret Baier Fox News Channel DC Bureau ____ Cb _H_ 6) ( cell) This messageand its attachments may contain legally privileged or confidential information . It is intended solely for the named addressee. If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee), you may not copy o r deliver th is message or its attachments to anyone . Rat her, you should permanently delete this message and its attachments and kindly noti fy the sender by reply email. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this email or its attachments are without defect. NIH-000518 From: (b)(6) Date: To: Subject: Mon, 16 Mar 2020 12:55:29 -0400 Victor ia Baron Re:Thank you Victoria: I saw it and thanks for sending it. Be st rega rds, Tony > On Mar 16, 2020 , at 12:53 PM , Victor ia Baron ________ (b)( _,> wrote: > > Dear Dr Fauci, > > I am a Cal ifornia resident and wanted to take a moment to thank you for your professionalism and integrity during this crisis with the Coronavirus. > > It is so evidently clear that you are forced to work "around" the ignoranc e, ineptness and narcissism of Dona ld Trump, yet you continue to provide the countly with the truth. > > I'm guessing that the odds of you actually seeing this emai l might be slim but l feel better for having sent it. You will be remembered as a hero during a very dark time. > > With Appreciation, > > Victoria Baron > (b) (6) > > Sent from my iPhone NIH-000519 From: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:54:30 +0000 To: Eisinger, Robert (NIH/NIAID) [E] Subject: FW: press release and "cheat sheet" Attachment s: NIAID press release mRNA Phase 1 FINAL.docx, CONDENSEDmRNA phase 1 talking points 3.14 CB.docx Date: Anthony S. Fauci, MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ai l and any of its atta chments is confidential and may contain sensitive info rmation . It should not be used by anyon e who is not the o rigi nal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its repre sent atives . --------- (b)(6) From: Billet, Courtney (NIH/NIAID) [El Date: Sunday, March 15, 2020 10:13 PM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El CbH ; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Stover, Kathy (NIH/NIAID) [El (b)(6) Routh, Jennifer (NIH/NIAID) [E (b)( >; Marston, Hila-ry- (:-:N'."'."'. IH "'."" /:"."'. N~IA~ID :-:)-::[-:: E]~=~-...:...--.a(b"'"" H= > --------, .....,..,= ~=======~ ~ Subject: ASF: press release and "cheat sheet" Attached, per discussion. NIH-000527 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 16 Mar 2020 11:03:39 +0000 Marston, Hilary (NIH/NIAID) [E];Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [El RE: URGENT:Confidential and urgent request regarding (b)(4) Thanks! From: Marston, Hi lary (NIH/N IAID) [E] _______ Se nt: Monday, March 16, 2020 7:00 AM -----~~ To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) 1· '= E-::-. ] ======= Cb _ >_C6) _ > (b)(6)> '"-' (b=)(= ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: URGENT: Confidential and urgent request regarding (b)(4) I will draft something for you today . (b) (5) I will send a draft later today. Best, Hilary On Mar 16, 2020, at 5:05 AM, Collins, Francis {NIH/OD) [El ------- (b)(6h wrote: Hi Tony and Hilary, See message below from Tom Hudson of Abbvie. Francis ----------- From: Hudson, Thomas J Se nt: Sunday, March 15, 2020 11:08 PM NIH-000528 (b)(6) (b) (5) (b)(6)> To: Collins, Francis (NIH/OD) [E] Subje ct : Confidential and urgent request regarding Dear Francis, I am sending this brief note as a request for guidance on an evolving situation w ith (b) (4) I am reaching out to you to see if you have any suggestions or individuals that we should contact . Best wishe s, Tom TH OMAS HUDSON Senior Vice -President, R&D Chief Scientific Officer AbbVie , North Chicago 1 North Waukegan Rd R473, Build ing AP9-1 N Chicago , IL 60064 TEL (OFF ICE) --~ (b)~(6) = EMAIL( .----------- abbvie.com This communication may contain information that is proprietary, confidential. or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this NIH-000529 communication is strict ly prohibited. Anyone who receives this message in error should notify the sender immediate ly by telephone or by return e-mail and delete it from his or her computer. NIH-000530 NIH-00053 1 (bXS) - PCP NIH-000532 From: (b)(6) Date: Mon, 16 Mar 2020 06:09:17 -0400 To: Lerner, Andrea (NIH/NIAID) [E) Subject: Fwd: Dental Respond Sent from my iPad Begin forwarded message: From: Date: March 16, 2020 at 5:54:34 AM ED T To: "Fauci , Anthony (NIH/NlAID) (E]" Subject: Dental ------------------- (b)(6) ,-------- ~= (b)( I ask you to addres s the explosion of concern s among the dental community in regards to COVID-19. We, the dental community , already high risk pe rsonnel , are at an even higher risk at this point and time. Many of thos e who do not work in the dental community are not aw are of how high risk our cun-ent situation is. For 8-12 hours a day we are creating aerosols while sitting 8-12 inches from a persons open mouth. These aerosols contain saliva and blood drop lets, along with billions of other bacteria and materials . In dentistry , saliva is considered a blood borne pathogen. Although OSHA requi res Level 3 masks for all aerosol producing procedmes, not all offices are complying. This DOES NOT matter anyway as we know SURGICAL MASKS DO NOT FILTER OUT THE COVID-19 virus. I ask that you suspend non essential dental pro cedures such as dental clean ings and other procedures that are non-emergent. That we triage patients and accept EMERGENCIES ONLY. We are at such a HIGH risk , not only to ourselves and our families, but a HIGH RISK to spreading this virus COMMUNITY wide . Many ofus are taking extra precaut ions but screeni ng patients, but with a up-to-14 day incubation period, that obvious ly does not matter. Plea se hear our plea to addJes s our concerns. The American Dental Association and the American Dental Hygienists Association has failed us. Thank you Alicia Jewell Sent from my Verizon, Samsung Galaxy smartphone NIH-000533 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Mon , 16 Mar 2020 10:07:04 +0000 Marston, Hilary (N IH/NIAID) [E] FW: lifting EUA COVID-19 ASM survey comments.docx Hilary : Please take a look at this and see if th e re is anything that we can do h ere. Th anks, Tony ------------- (b)(6)> From: Bertuzzi, Stefano Date: Sunday, March 15, 2020 8:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Segal, Allen CbH6l;Melissa Miller __ ..;;:_ .;___-======;:;;,,:,;:;---:-----:-~~~----:-(b)(6)> ; Stevens-Garcia, Jonathan ... M-L~======= (b =-= ,-=c~.,__________ ary ee , Subject: Lifting EUA ~= (b)( _, '>; Wat t s, -------- Hi Tony- Per our conversat ion , see the attached email asking FDA to lift the EUA, which would allow CUA hospital labs to ramp up test capacity significantly . We have sent this letter also to Francis and to Adam Boehler and were on a call with them . Jeff Shuren at FDA also knows , but we think it will be important to take action quickly. Many thanks, let me know if you need anything else from me at this time . Sincerely , Stefano Stefano Bertuzzi , Ph.D., M.P.H. Chief Executive Officer Ame rican Society for M icrob iology (ASM) 1752 N St., NW Washington, DC 20036 -2904 Phone (b)(6) NIH-000534 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 16 Mar 2020 10:07:03 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: TytoCare: COVID19Telehealth Support To: Subject: From: David Bardan (b)(6)> Date: Sunday, March 15, 2020 9:25 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Shriya Palekar Subject: TytoCare: COVID19 Telehealth Support Importance: High (b) '""' (= 6)> Hi Dr. Fauci -good evening. I represent TytoCare, a company that built the industry's first and only allin-one medical device that pairs w ith a virtual exam, going beyond the means of audio and visual. Tyto Home, an OTC and FDA approved/c leared device is meant to either synchronously or asynchronously examine a patient with capabilit ies to capture heart/lung/gastrointestinal sounds, ear/throat/skin exams, and temperature . Due to the outbreak of COVID-19, Tyto has experienced an influx of orders worldwide to support those that need to be monitored when quarantined. I would like to offer Tyto's assistance here in the U.S. and think through ways and oppo rtunities that the product can make a difference. Please see a few a couple of examples on how Tyto is making a difference below : • • Patient Quarantine/Dischargeat Home o Design: patients receive TytoHome or have it delivered for remote evaluation by infectious disease specialists • Example: Home Admission Service with TytoCare Create & manage quarantine locations, onsite or offsite o Setup: Patients do a self-exam with TytoClinic while a prov ider evaluates them from a distance • Patient is remotely guided to fully disinfect the device and station before it 's returned to staff for a second round disinfection • Example: Nursing Home Triage Thank you for all that you do during this difficult time . Thanks, David David Bardan Vice President, Provider Solutions m: (b)(6) NIH-000535 2 15 W 40 th Street , 9 th Floor New York, NY 10018 www.ty toca re.com ~ t~tocare... NIH-000536 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Mo n, 16 Mar 2020 10:07:03 +0000 Lerner, Andrea (NIH/N IAID) [El FW: Leronlimab Please check out and respond . -----Original Message ----From: nicho las Agresti ...__________ Date: Sunday, March 15, 2020 9:15 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Leronlimab --------- ..-,a-s-= < -----~~ (b_~..... (b)( > Dr. Fauc i, Tcan't even imagine how busy you are. r am a gastroen terologis t in for coronavirus. Any word on results of the clinical trial? Thank you N icholas Agres ti MD NIH-000537 ---(b) (6) Geo rgia. I read about Leronlimab From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 22:52:4 0 -0400 Lerne r, And r ea (N IH/NI A ID) [E) Fwd : COVID-19 Please handle Sent from my iPad Begin forwa rded message: From: Deb W hitney Cb)(6Jl Date: March 15, 2020 at 10:28:48 PM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" ---------~~ Subject: COVI D-19 ----------- CbH6) Thank you for you r frank speaking about COVID-19.1 cred it you r willingness to stand up and speak aloud that "the emperor has no clothes " ... You have already helpe d so many through the current pandemic . I know you will understand my concern. But, please help me spread this message as we ll. In light of public school closures ...these include chil dre n and young people from kindergarten through high school. These closures also include preschool programs (Volunta ry Pre- Kin Florida) for 4-year-olds that are part of a public elementary school. These school closures do not apply to children whose ages range from infants through preschoo l (including VPK) receiving care and education in pr ivate, corporate , or fa ith - based centers . My center is one of these , and we are not closing. This is a business decision. No kids = No money . At what price ? We have more t han 90 infants, todd lers and young children enro lled at ou r center, with 20-plus employees on premises thro ughout the day between the hours of 6:30 am and 6:00 pm . Ours is a 5-Star rated, NAEYCaccredited preschool program . I have 17 t h ree-year-old preschool childre n in my classroom on any given day, with 3 t eachers assigned to this room. This is a high quality program . Please expla in how I am supposed to take recomme nded precautions against COVID-19? Does social distance apply only to adults? If not, please help me know how to maintain social distance of 3 feet between child ren and adults at arr ival or departure times when I am helping a child with separation from their prima ry care giver o r saying goodbye at the end of t he day? How do I maintain social distance between children during center time in the block area , in the NIH-000538 dramatic play area, in the classroom library or computer center, during story time or music circle? Our 3 table surfaces are used for multiple activities through the day including mealsand they seat six children at each table. Friday afternoon, I had 9 children sharing space and materials engaged in cooperative play for an extended period outside in a sandbox that measures S'xl0' ...you do the math. Our spacing for cots at nap time is considerably less than 3 feet. We have no hot water in our classroom for hand washing for children or staff which is considered a safety measure. We are relentless in our efforts to teach hygiene to 3-year-old children who cough, sneeze, vomit upon (and occasionally may spit, bite or lick) each other or a staff member. we work to teach them to use a tissue instead of their hand/arm/shirt to wipe a runny nose...then throw it in the trash and wash their hands again. Believe me when I say a determined child can sing "Happy Birthday" twice in an amazingly short time--definitely less tha n 20 seconds--all the while whipping through instructions to wash the tops, bottoms and fingers of their hands while they sing. Hand washing is monitored by 3 adults through the day to ensure it happens after each cough, sneeze, nose wipe and use of the bathroom. Hands are washed after sensory play indoors or out, before am snack, lunch, and pm snacks (and sometimes during), and when we transit ion from outside play. At a minimum, these 17 children are taking turns washing hands (at ou r single sink) six times during a full day at preschoolbefore we add in those runny noses, coughs or sneezes. Avoid touching shared objects ...seriously? We work daily to teach these 3-year-olds to share materials and space. Yes, we disinfect our toys regularly and our room daily--but that stuffed animal may move from dramatic play to the reading nook and to a nap cot all in one day and may be held by a different ch ild with each move. our families send a blanket from home for their child to use through the week at nap time-along with a soft "s leep toy" if this is needed, to sooth their child to sleep. These items are stored in the child's open "cubby box" in the classroom through the week . Do we know how log COVID-19 "l ives" on soft surfaces? I am convinced school closures are necessary at this time to stem community spread of COVID- 19. I understand the strain on multiple levels this will inevitably put on families to provide care for and education of their own children for this period. But-young children can contract this virus and can spread it even though they may not demonstrate symptoms themselves. Or, what may be dismissed as allergies or "just a cold" may not be. Young children can carry this virus home to their fam ily and neighborhoods just as easily as a school age child; and, they can certainly bring it into our center from their home . How many of our children in preschool depend upon elderly family members for their care? We have infants as young as 6 weeks old and children th rough 5 years old at our center . How many young children in care are we willing to expose? How many and which grandparents are we go ing to risk? (b)(6) ---------------------- (b)(6)l Forget sporting events, museums, concerts or even worship services--1am worried about going to work on Monday ...and uncertain what may happen if I stay home. Again ... This is a business decision. NIH-000539 No kids = No money At what price? Respectfully, Deb Whitney NIH-000540 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 22:48:23 -0400 Glen Goldmark Re:Thank you Glen : Tha nk you for your kind note. Be st rega rds, Tony Sent from my iPad > On Mar 15, 2020. at I 0:39 PM. Glen Goldmark _______ (b _ )_~_ > wrote: > > Dr.Fauci, > > You are my hero! Thank you for being the voice of reason and credibility dur ing the COVID -19 crisis. > > All the best, > > Glen Goldmark NIH-00054 1 From: (b)(6) Date: Sun, 15 Mar 2020 22:43:39 -0400 To: EmoryFord Subject: Re:Great Job Em ory: Thank you for your kind note. It is much appreciated . Best rega rds, Tony Sent from my iPad > On Mar 15, 2020 . at 10:23 PM . Emory Ford ______ > > Dear Dr. Fauci: (b _)_(6> _. wrote: > > You are doing a great job and a great service to the cow1try. Amid the chaos you are one of few voices that provides clear, accurate information on the coronavirus pandemic. > > Plea se continue providing that service despite the presid ents continued effort(s) to spin the situation with misleading and false information. In the end biology wins , the virus ignores political needs and wants. > > Emory A. Ford PhD NIH-000542 From: (b)( 6) Date: To: Subject: Sun, 15 Mar 2020 19:38 :20 -0400 Conrad, Patricia (NIH/NIAID)[E) Fwd: "LeadingThrough A Time of CrisisIn Healthcare" - ZRGThought Leadership Sent from my iPhone Begin forwarded message: From: Greg Gerson Date: March 15, 2020 at 7: 34:59 PM EDT -------~= To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( > Subject: "Leading Through A Time of Crisis In Healthcare" - ZRG Thought Leadership Hi Dr. Fauci I am reaching out as you have been doing an incred ible job as part of the White House Coronavirus Task Force. These are difficult times and you seem to prov ide the most informative interviews without send ing signals of panic to the American public. Not sure if you remember, but we we re in touch years back through many executive clinical leadership searches I conducted during my 18 years at Korn Ferry . I am now leading the hosp ital/hea lth system practice for ZRG. ZRG is an innova tive global boutique firm disrupting the traditional execut ive search industry . As a result of the COVI0-19 crisis, I am speak ing with/ interviewing many heal thcare leaders (Chief Medical Officers, Hospital CE Os , Lead ing Scie ntists , etc.) as part of a thought leadership piece . The topic is "Leading Through a Time of Crisis in Healthcare". I know you are extremely busy with the task force, but I would very much appreciate if you have some time for an interview/call. As you know , strong leaders hip is cruc ial in times of crisis and we are facing weeks /months of extremely important decis ions by our healthcare leaders nationwide. Do you have any avai lability over the next few weeks to connect? I will make myself availab le to meet and/or have a video or phone call at your convenience. Hope to hear from you soon. Regards , Greg NIH-000543 Greg Gerson Managing Director ZRG Partners, LLC Americas EMEA Asia Pacific C: (b)(6) 0: 215-422-3576 mJ Z RG p a rtn ers com •• The informa tion and attachments in this e -mail is the property of ZRG Partners, LLC and is confident ial and may be privileged . If you are not the intended recipient , please destroy this commun ication and notify the sende r immediately . You should not reta in, copy or use the contents of this e-mail for any purpose , nor disclose all or any part of its contents to any othe r person or persons . NIH-000544 (b)(6) From: Date: Sun, 15 Mar 2020 19:37:43 -0400 To: Lei Wu Subject: Re: Please shut down the country NOW Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 7:35 PM , Lei Wu ------- (b)(6)>w rote: Dr. Fauci. This is Lei Harrison. In the coronavirus crisis , as a former (b)(6) I have been calin until now. No one can anymore after seeing the photos of the international airports today where hundreds if not thousands of people standing in line for 5-6 hours and reali zing immediately the virus transmission will explode exponentially because of this. I strongly request: ------------- 1. Shut down the country NOW. Mobility has to be as low as possible. We have to do the very best RIGHT NOW to break the transmission chain. 2. Please talk to Dr. Zhong Nanshan (tlfl¥j LU) , the Chiense doctor and advisor during the coronavirus crisis. His advice and experience would be of tremendous value for the U.S. now. 3. Sofar, we've been acting in a reactive instead of proactive fashion. Not anymore. People need to realize that we are entering war time. We need to act fast, in light speed to beat the virus. 4. Healthcare worker s need to most strongly protected - treat it as airborne if needed at the hospitals and pharmacies. Supplies of essential protective medical supplies for healthcare workers are equally important as supplies needed for the patients. Make sure supply chain from China is uninterrupted; and have American companies to start making masks, ventilators etc. Plan ahead. NIH-000545 5. Grocery store and restaurants can potentially become a hub too. They need to have high level of hygiene, and ideally no contact with the customers. 6. Garbage and belongs and bodies need to be burned. 7. Safety protocol at the labs, public and private labs that have access to the virus or experimental animals with the virus. 8. Plan ahead. Instruct patient to self-treat or be treated by family at home. If we ever come to it, recruit and train volunteers ( how and whom?) to help taking care of patients. Dr. Fauci. Clock is ticking. It's a race against time. And it's time that every single American takes responsibility. Please lead us through the crisis. Respectfully, Lei Harrison NIH-000546 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:37:15 -0400 Lori Hall Re: Real EstateAppraisals-Coronavirus (COVID-19) Thank yo u for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020, at 7:35 PM , Lori Hall _________ .... (b)( 6bwrote : Dr. Fauc i, Thank you for your impor tant work and for educa ting the public. Earlier today I sent the message below to President Trum p. I am writ ing out of concern both for my husband's safety, others in the industry, and knowing refinances (especially with low rates) will help the American people through this unpre cedented time. I unde rstand that om Loca l and Nat ional Govern ment continues to look at all potent ial solutions, with advice from experts such as yourse lf. I fully under stand this suggestion from one mom and wife might be way too simplist ic for banks/lenders to even cons ider. I am hoping to be ahead of the curve and that it starts/cont inues what I cons ider to be a much needed conve rsati on for this indust ry, for the safety for apprai sers and homeow ners alike, and for the pipeline for the lenders. It's very much appreciated. Be Safe. Kindes t Regards, Lori Ha ll Dea r Mr President , First , our great apprecia tion to you and your staff for all you do every day and in keep ing our countr y &ci tizen s safe . We have a family real estate appraisal business (Chicago Metro Area). I hand le all service related items from the comfort of my home. However, my husband, William Ha ll, who is a Cer tified Gen eral Rea l Estate Appraise r, is out in the field all day perform ing interior appra isa ls. I have reac hed out to all our appraisa l management compa nies with this quest ion to ask their lend ers. Considering the abundance of caution everyone is taking and the refinance industry seeing unprecedented volume, is there any talk about lender s moving to exterior only appra isals (and possibly following up after with an interior)? We heard from ServiceLink, a Fidelity company, and they have not heard any word from their national banks/lenders changing to exterior only apprai sals at this time . Thank you very much! God Bless, Lori Hall NIH-000547 Best Regard s, Lori Hall For updated real estate news &more, please visit our website at: www.alphavalues .net NIH-000548 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 19:11:49 -0400 Gandam, Shyam Kiran Re: Front line physicians in limbo need ing reassurance Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 4: 13 PM , Gandam , Shyam Kiran (b) < >wrote : Dear Dr.Fauci, I would like to congratulate you for your excellent work and thank you for leading us in the fight against COVID-19 pandemic . We are 14 critical care physicians and almost 30 hospitalist physicians at Memorial medical center and HSHSSt. John medical center in Springfield Illino is and are the frontline workers in dealing with the situation . We are developing protocols and creating safety net for the hospitals and community with the help of your guidance. I would like to bring up an issue plaguing us with concern for years and now even more so. It concerns us and more importantly our helpless fami lies. It might be untimely to bring up this issue but it is very important for us and our families. (b)(6) Dur ing thi s pandemic, it's imp ort ant th at physicians can help oth er areas in the country in nee d. Immi grant work for ce on Work Visa (H-1 visa) constitute s at least 50% of physicians. (b)(6) (b)(6) Your assist ance in bringin g up t hese issues w ith th e president will he lp us work with reassuran ce fr om governm ent and help our communi ty with peace of mind. NIH-000549 Again, We thank you for the hard work you and your t eam are putting to guide us in these tumulus times. Regards, Shyam Kiran Gandam MD Critical Care Medicine Associate professor, SIU school of medicine Springfield Clinic Springfield, Illinois NIH-000550 From: (b)(6) Date: Sun, 15 Mar 2020 19:10:41 -0400 To: ABCDEFGHIJK Subject: Re: COVID-19 • The necessity of using fluo rescent light lamps to prevent or reduce or slow down the spread of coronavirus Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 15, 2020 , at 4:15 PM , ABCDE FGHIJK ---------- (b)( >wrote : Dear Dr. Anthony S. Fauci, It's critical to disinfect droplets, aerosols and surfaces continuous ly to prevent or reduce or slow dow n the spread of COV ID-19. The best way is using UVC ultraviolet light. UVC's wavelength is germicidal and it is capable to inactiva te coronavirus by destroying nucleic acids and disrupting its DNA because Waveleng ths between about 200nm and 300nm are strongly absorbed by nucleic acids . The absorbed energy can result in defects including pyrimidine dimers. These dimers can prevent replication or can prevent the express ion of necessary proteins .resulting in the death or inactivation of the coronavirus. Fluorescent light lamps emit ultraviolet (UV) light , including UVC ultraviolet light. I think it's necessary to use fluorescent tube light lamps and CFL (Compact fluorescent lamps) lamps in hospita ls, Health centers, stores , supermarkets, elevators, public lavatory , toilets, restrooms and other public places and should always be on 24 hours a day, 7 days a week in order to be effective. Research has shown that Fluorescent light lamps must be installed without any glass shade or decorat ive shade and should be at least 40 watts . I hope you find the UVC-based continuous disinfection solution helpful. Thank you for your time and consideration. Sincerely, P.Salimi NIH-000551 From: (b)(6) Date: Sun, 15 Mar 2020 19:09:44 -0400 To: Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Subject: Sent from my iPhone Begin forwarded message: From: Sia Hersini (b) (6J Date: March 15, 2020 at4:15: 21 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Dear Dr. Fauci, Many yea rs ago, I did so me resea rch on the effect of SIV infect ion on the Macaque immun e response . I have some thoughts on the current COVID -19 spread and in general about other virus with unknown cure or immunity vaccine. In research, we have adhered to a scientific method necessary for the protection of the public in the development of new technology and treatment. There are times how eve r whe n that Boyle method and ph ilosophy should give way to Desca ,t es approac h. The current infection has thus far shown a predilection for causing severe illness in men more than women and in adults over 30 sparing children from mortality. I believe there is a reason for this and it's not because of past exposure to other coronovirus strains. I believe it is because of children being in the middle of or having recently completed their immunization schedule for school. These immuni zation s are abso lutely not prov idin g an immuni ty to COVID-19, BUT, th ey are caus ing an increase in the numb ers of gamma delta t ce lls and NK cells . The child ren are responding better to a viru s with an 5 .1 day median incuba tion period because of the higher values of gd and nk cells. Women hav e a better gd and nk: cell response to the flu and other viral infections which could explain why there is a gender difference in mortality. I would suggest that adults update their vaccines and especially the hep b. Interestingly, the hep viruses illicit a better gd and nk cell response and although most Western countries require hep b for health care workers, the immunization rate in China is only 60% which may explain the high mortality among health care prov iders. NIH-000552 This has been on my mind for a few days and I felt I should share. Th ank you for your time Sia NIH-000553 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 19:09:26 -0400 Eliot Robinson Re: Pre guidance on coronavirus Thank you for your note. A.S . Fauci. Sent from my iPho ne On Mar 15, 2020, at 4: 15 PM, Eliot Robinson wrote: Dr. Fauci, thank you for all you do . one of my chinese friends sent me the attached pre guidance on corona virus. it includes both western medicine as well as traditional medicine approached. On its face, it seems to be complete and very up to date. I apologise for your having to follow of dear leader trump' s instructions to praise him. thanks eliot Eliot Steele Robin son Robinson Ma nagemen t Serv ice 4290 Bella Casca da Street Las Vegas, NV 89135 -2436 CbH6)(cell)702-330-9921 (fax) Eliot@RobinsonManagementService.com https://www.Rob insonMan agementServ ice.com DUNS 079879598 CAGE 7EEU6 JCP 0073645 ----- NIH-000554 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 19:06:03 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Coronavirus From patty Pis respond. Sent from my iPhone Begin forwarded me ssage : From: Kathleen Quinlan Date: March 15, 2020 at 5:16:22 PM EDT (b)(6) To: "Fauci, Anthony (NIH/NIAID) [E]" --------=-::-:-= (bH > Subject: Coronavirus -------- Dear Dr . Fa uci, I have a question which has been troubling me since we began checking people's temperatures. --------. (b)(6) _ I have seen the temperature cutoff is 99.5F. (b) (6) ---------------------------- ? I doubt very much that in screening people the question is asked them whether they have taken a med icin e for pa in or for fever in the last 24 hour s. I am a nur se and many people do rea lize that the common pain relieve rs also re lieve feve rs. Shou ld we up our game and do be tter at screening? You seem to be the wisest person on the government task force for the Coronavirns. I hope this reaches you. Thanks, Kathy Quinlan P.S. P lease practice socia l distancing during the White Hou se briefing,etc. It is hard to watch all of you people bunched around the President and telling the pub lic to stay 6 feet apart. If you do it maybe the others wi ll follow suit. Sent from my iPad NIH-000555 (b)(6) From: Date: Sun, 15 Mar 2020 19:04:54 -0400 To: Subject: flippi 333333 Re:Coronovirus Thank you for your note. A .S. Fauci. Sent from my iPhone On Mar 15, 2020, at 5:22 PM , flippi 333333 ---------- (b)(6) wrote: Dr. Fauci: Sending all students home may be increasing the spread of Covid-19 in the us because the young people now off college, middle and high school, see this as a vacation to go out and frequent social businesses, parents are taking kids out to enterta in them, and they are traveling to visit friends in other cities and states, all aiding the spread of Covid-19. Please cons ider more strict MANDATES TO ENFORCE TEMPORARY CLOSING OF RESTAURANTS, BARS, BOWLING ALLIES, MOVIE THEATERS, MALLS or other places of gathering and TRAVEL ONLY IF IT IS AN EMERGENCY, to mitigate the increasing cases of Covid-19 in the US. People are clearly not taking the advice given to minimize social or publ ic gatherings . In order for our United States not to follow the same fate as Italy , we need mandated changes asap. Please conside r telling peop le over 60 or 65 to also stay home from work for a 2-week period. Thank you very much for your fine leadership in this critical matter . Concerned paren t and scientis t, Robbin. NIH-000556 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 19:02:51 -0400 Luanne Novak Re: Corona virus suggestions Thank you for your note. A.S. Fauci. Sent from my iPhone ---------- > On Mar 15, 2020, at 5:39 PM, Luanne Novak (b) (6)> wrote : > > > Dear Dr. Fauci: > > First, thank you for your honest and forthright testimony and advice during this crisis. Your calm but serious approach is a great comfort to me. (b) (6) > > He is a Pharmacologist by training, and taught physiology at the School of Health Professions at Baylor College of Medicine until he retired in January. We have been discussing the COVID - 19 situation and he has severa l sugge stions. (b) ( . > > 1. Since South Korea got such a quick handle on this situation, could we buy their tests? Since it has taken such a Jong time for the US to gear up, could we not just buy their system turn-key? > > NPR reported that there is a national stockpile of respirator s - when will those be released ? > 2. Since China appears to be back online , can the US contract with them to build mechanical respirators to replenish our "strateg ic reserve"? > > l hope that you will continue to be able to speak the truth, and that you stay healthy. > > Many thanks, > Luanne Novak and David Johnson , PhD > (b) (6) NIH-000557 From: Date: To: Subject: Pandemic (b)(6) Sun, 15 Mar 2020 19:01:28 -0400 Daniel Gutstein Re: Daniel Gutstein: Regarding Synagogue Services during the Covid-19 Thank you for your note. A.S. Fauci. Sent from my iPhone > On Mnr 15, 2020 , at 5:53 PM, Dan ie l Gutstein --------- (b)(6) > wrote: > > > Dear Dr. Fauci , > I would like to commend you for providing needed doses of stabi lity and reas sura nce to our nation at this troubl ed tim e. Your knowledge and professionalism ha ve been indispensable to the masses. I am an assistant to the rabbi of a Jewish congregation in Chicago which holds services thrice daily. Due to the tight-nit natw·e of the large r Jew ish community, many synagogues in the city and surrounding suburbs have closed indefinitely in order to limit the community spread of the Covid - l 9 virus. (One person visiting the community from New York and who interacted with numerous individuals has so far tested po sitive.) Our synagogue is few in parishione rs though is an essential sanctum of sustenance and faith to those who make usage of its services. We would like to keep our doors open for the longest duration possible but remain cognizant of the 1·ealities of the pandemic. Consider ing that we gather in a sanctuary of impressi ve size with usua lly no more than 20 members who are sta tioned at a distan ce apart from one another, would it be responsible to continue services for the remainder of the week and this upcoming Sabbath so lon g as no specific member of the congregation itself has contracted the virus? > Thank you . > Wis hing you sustained health and much success , > Daniel Gutstein NIH-000558 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E] Sun, 15 Mar 2020 23:00:03 +0000 Talbert, Patricia Y Re: Public Health 101: -- Please listen to my Public Health Cry/Recommendation Outlook-1516124588.jpg Thank you for your note. AS . Fauci. Sent from my iPhone On Mar 15, 2020, at 6: 14 PM, Talbert, Patricia Y wrote : Greetings Dr. Fauci, As you know, we are currently experiencing a public health pandemic, Coronavirus (COVID-19). I am asking that you take a moment to listen to Fareed Zakaria's show that was aired today, Sunday, March 15, 2020, at (https://www.cnn.com/shows/fareed-zakaria-gps ). Please listen to the message and review the attached chart that was presented on Fareed's show. This is NOT about politics, but instead the people. Therefore, let's call to action that the United States of America government officials and leaders call for a mandate similar to other countries, such as China, Italy, and Spain (i.e., now, New York & Illinois) to help reduce the spread of this virus, flatten the curve, reduce the inundation to our healthcare system, (which is about to experience the worst morbidity and mortality outcomes), and work to save lives. There are too many unknowns for us to continue to go on as status quo. Let's be public health officials and petition to mandate the US Administration to move to action - by putting in place a Mandatory Shutdown of Movement throughout this Country. Currently, we have approximately (9 airports in the United States) in total chaos, which will be another wave and spread of this virus. We are not proactive; instead, we continue to react late. This is not the public health that I know and have seen throughout the duration of my public health vocation. We have to change this Pandemic, so let's get to work. #Cry for Pubic Health Action Needed -----****We need this Administration/Government Committee to LockDown the United States of America. This can slow down the spread of this disease, save lives, and maybe within 30 days we can get back on our feet. Warm and sincere regards - please push action. NIH-000559 Dr. Pat Talbe rt Dr. Pat Y.8. Talbert Patricia Y. B. Talbert, PhD, MPH,MS, CPHA,CHES,cPHN Associate Dean of Academic Affairs and Administration Howard University, College of Nursing and Allied Health Sciences Healt h Sciences Executive Suit e, Towers 6000 2041 Georgia Avenue NW Washington DC 20059 Email: patric ia.talbert@howard .edu Howard U: https ://home .howard .edu/ CNAHS: https ://cnahs.howa rd.edu/ Cell#: (b)(6J "Of all the forms of inequal ity, injustice in health care is the most shocking and inhumane." Rev. Martin Luther King, Jr. "Once a task is just begun, never leave it till it's done. Be the labour great or small, do it well or not at all." Quincy Jones THE TIME IS ALWDS NOW 150 HOWARD UNIVERSITY SESQUICENTENNIAL --- 1867 - 20 17 --- ExcellenceanTruthand Service NIH-000560 THE TIME IS ALWAYS NOW 15Cl ~ HOWARD UNIVERSITY -Qu:~ -~ENNIAL Excellencein Truthand Stnict From: Date: (b)(6) Sun, 15 Mar 2020 18:58:40 -0400 Lindley Lee Re: Under 10 Minute P-O-C Testing Reported by Colorado To: Subject: Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 6:22 PM , Lindley Lee ---------- (b)(6) wrot e: Dr. Fauci, I am not sure you are aware, but there is already a point-of-care solution available for Coronavirus, and the Denver newsrooms have been reporting about it. 9News and FoxNews are all reporting about Aytu Bioscience of Englewood, Colora do. The kits have already been used in China, and are immed iately available to assist burden the testing time and ba cklog. Who do we need to inform of this already available option? Thank you. Regards, Lindley Lee (b)(6) NIH-000562 (b)(6) From: Date: To: Subject: Sun, 15 Mar 2020 18:58:19 -0400 JOHN Lightbo dy Re:Thank You! Thank you for your note. A.S. Fauci. Sent from my iPhone On Ma r 15, 2020 , at 6:22 PM , JOHN L ightbod y --------- (bH6)wrote: Dear Dr. Fauci , Thank you for your service and your honesty. It is difficult for me to watch you telling the truth with all of the people of the T rump Administration spouting lies constantly! Keep up the good work! Our prayers are with you and those who are working to help this country deal with this coronavirus. Sincerely, Sonja C. Lightbody (proud (bH6) federal employee) (b)(6) NIH-000563 From: Date: (b)(6) Sun, 15 Mar 2020 18:58:06 -0400 Clarence Jones Re: A Telemedicine Book to help Doctors & Staff Cope w ith the COVID-19 To: Subject: Overload Thank you for your note. A .S. Fauci. Sent from my jpbone On Mar 15, 2020, at 6:22 PM, Clarence Jones wrote: Dr. Fauci: If your predictions come true, the entire medical system will soon be overwhelmed. Only massive use of telemedicine will be able to cope with the over load. I'm a former TV reporter, now full-time wr iter , with nine books in pr int. One of them - "Webcam Savvy for Telemedicine" -- can help th ose in the medical community quickly learn how to use this medium. It is available at amazon.com in both print & digital versions. https://smile .amazon.com/Webcam-Sawy Telemedicine-ClarenceJ ones/ dp/1546501894/ref =sr 1 f kmr0 1?keywords=webca%2C+savyy+for+tel emedicine&gid=1584307097&sr =8- 1-fkm r 0 I'll attach a PDF copy t o this message & also send the same message without an attachment, just in case your system rejects messageswith att achments. I can also overnight you a print copy if you'd like . Bulk pricing is available for both print & digital versions. You've become a rock star in the current crisis. As a long-time on-camera coach, I don't think I could teach you a THING you haven't already mastered . Congratulations. Cheers, Clarence Jones (b) (6). NIH-000564 (b)(6) Landline: Cell:--=~ (b) (6) (b,:,,:: )(~6)r-- website: www.winning -newsmedia.com Books by Clarence Jones in both print and e-book versions: LED Basics: Choosing and Using t he Magic Light Sweet hear t Scams - Online Dat ing's Billion-Doll ar Swindle They're Gonna Murder You - War Stories From My Life at the News Front Winning with the News Med ia - A Self -Defense Manual When You 're the Story Webcam Savvy - For the Job or the Ne ws W ebcam Savvy- For Telemedic ine Filming Family History - How t o Save Great Stories fo r Future Generations Sailboat Projects - Clever Ideas and How to Make Them More Sailboat Projects - Clever Ideas and How to Make Them NIH-000565 From: (b)(6) Sun, 15 Mar 2020 18:57:17 -0400 To: NIAIDODAM Subject: Fwd: CANCELUHION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Date: Sent from my iPhone Begin forwarded message: From: (b)( Date: March 15, 2020 at 6:25:06 PM EDT To: "Fauci , Anthony (NIH/NlAID ) [E]" (b)(6) Cc: "Folkers, Greg (NIH /NIAID) [E]" (b) (6), "Conrad, P atricia (NIH/NIAID) [E]" (b)(6) Subject: CANCELLATION amfAR Capitol Hill Briefing, Ending the HIV/AIDS Epidemic on Thursday, March 26th Reply-To: (b)(6) ---------::-,:-:-= Dear Tony: amfAR, The Foundation for A IDS Research will be postponing our Capitol Hill Briefing, "Ending the HIV/AIDS Pandemic: Lessons Learned for the Coronavirus Outbreak" planned for Thursday , March 26th, due to the declaration of a National Emergency in our country. Once the coronavirus public health crisis abates, amfAR will reschedule the briefing and hope that you will be able to speak as planned. At that meeting , you and several other of our nation's leading health officials will address two pandemics - AIDS and COVID-19. and the lessons learned from fighting both of these diseases. We will very much look forward to hear ing your perspectives about global initiatives for ending AIDS and the work done to erad icate the coronavirus pandemic. We know your remarks will help provide a roadmap for ending HIV and other infectious disease threats now and in the years ahead. I was proud to see the contributions of the US Public Health Service highlighted in today's WH briefing. You did an excellent job with your remarks. Tha nks for your work and dedication to safeguarding and advancing globa l health. Hope we get a chance to catch up soon . Sincerely, Susan Susan Blumenthal , MD, MPA Senior Policy and Medical Advisor, amfAR Rear Adm iral (ret) Former US Assistant Surgeon General First Deputy Asst Secretary for Women's Health NIH-000566 From: Date: To: Subject: (b)( 6) Sun, 15 Mar 2020 18:56:55 -0400 Linda Jones Re: Emulating Social Distancing During Press Conference Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 15, 2020 , at 6:25 PM, Linda Jones (b) (6) > wrote: > > Thank you so much for all your EXTREMELYIMPORTANT info on COVID-19. You are a national treasure. Please emulate Social Distancing during ALL press conferences and the press Corp as well. > Please be safe and stay welI. > Linda Jones > > Sent from my iPad NIH-000567 From: Date: Sun, 15 Mar 2020 18:55:37 -0400 To: el Subject: Re: Coronavirus Cases in New Jersey (b)(6) Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 6:30 PM, el -------- CbH >wrote: De ar Dr. Fauci, My apo logies if you have already spoken with Mike Maron, but it seems the political machine here :inNew Jersey is ignor:ingour own medical experts and I thought it important that your team be aware of how this crisis is manifesting on the front lines: https://WW1.v. roi-n j.com/202 0/03/ l 4/opiruon/li fe-at-the-epi center -of-n -j-scoronav irus-outbreak/ Om family is keeping you and your team in our thoughts and prayers. With infinite respect for you and the daunting task you face, Rosanna Galluccio NIH-000568 From: Date: (b)(6) To: Sun, 15 Mar 2020 18:52:24 -0400 Eva Sperling MD Subject: Re: For your urgent attention (COVID-19) Thank you for your note. A.S . Fauc i Sent from my iPhone On Mar 15, 2020, at 6:38 PM, Eva SperlingMD --------- CbH6) wrote: Dear Dr. Fauci, Thank you for your leadership during the current COV ID-19 crisis. We're writing to ask you to consider spearheading an additional initiative in this effort. As you know, one of our greatest immediate needs is an adequate supply of ventilators for use in hospitals . We will face a severe shortage of this crucial equipment during a surge of COVID-19 hospitalizations. This will creat e a bottleneck in our ability to de liver care , a situation where we have to triage who should live and who should die . Tragically, we see this happening already in Ita ly. This is a situation we must avoid. So we propos e to immediately help existing fac tories to increase production , to convert other existing factorie s for the production of ventilators and to build new factories to do so. Some of this will take a long time to accomplish but this pandemic is also predicted to be w ith us for a long time. We must stay ahead. We should make an all-out effort to supply our hospitals properly and quickly. We are in a time of war and we must make the commensurate effort now. We believe we have the knowledge and the resources to do such a thing. We just need the will, and the leadership. We're writing to urge you to use your position of leadership to make this happen. Here is a link to NPR's report on this crucial issue: https://www .npr.org/sections/healthshots/2020/03/ 14/8156 7567 8/as-the-pandemic-spreads-will-there-be-enoughventilators Thank you, Eva Sperling, MD Elisabeth Sperling NIH-000569 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 15:33:20 -0400 Xiaoyang Hua, M.D., Ph.D. Re:COVID-19some suggestions Thank you for your note Sent from my iPhone ---------- > On Mar 15, 2020 , at 3:17 PM, Xiaoyang Hua, M.D. , Ph.D. (b)( > wrote: > > Dear Dr. Fauci: > Jam writing to you to express my deepest concerns on the COVTD- 19 outbreak in the USA and would like to share som e though ts with you. > > I am a (b) (6) and an otolaryngo logist at the Duke Medical Center. I completed my training in Otolaryngology at the University of lowa in 2019. From 2013 to 20 I 5, l did a research fellowship with Dr. Stanley Per lman , an expe rt in corona virus , to study SARS. Before I came to the States, I was an ENT doctor and had worked in the epicenter of the COVID- I 9 outbreak, Wuhan, China for several years. Many of my friend s, neighbors, and colleagues were infected . Some of them have died or are dying. I truly appreciate what you have done to wake the Americans and warn them about this dangerous virus outbreak. J hope we arc not repeating the mistakes that the Chinese and Ita lians have made earlier. > > I know many physicians and nurses who have been on the frontlines against this coronavirns outbreak in Wuhan China. Over the past a coup le of months , I have been communicating with them about the COVID-19 ou tbreak. T have obtained much firsthand information about this virus from medical profess ionals, including the ICU directors of major hospitals in Wuhan. Here l want to share some thoughts with you and hope that I can help prevent the worst in the USA . > > For the government: > > I. Close all public school s immediat e ly. My family is in (b) (6). They are yet to decide if they should close the schools after the spring break . This is one example that has concerned me a lot. In the email from the (b) (6) School Distr ict, quote: "there are many factors to be considered any time a decision is made to close schools. These factors range from eva luating the consequences of missed instruction to providing meals to students who rely on the school's food service program ", this is extremely short -sighted . These factors, as quoted above, will be very minor issues and easier to handle, compared with the potential catastrophic consequences should the virus outbreak be out of control and have para lyzed ow· already -overwhelmed medical system in the USA. I hope the foderal government can issue an administrati ve order to close the public schoo ls. > > 2. Cance l or postpone any large gathering events more than 20 people. Use tele-conference if necessary. > > 3. Every county in this country should have contingent plan in place and have one or several isolation fac ilities/temporary shelters in the remote areas using co!Jege dorms or hotels, in preparation of future large outbreaks ofCOVJD-19 in the community. > > 4. Work with local or state media to inform the pub lic oftbe status of basic life necessity (e.g. food, water, tissue paper) and essential med ical supplies (including PPE). If there is a shortage, the estimated back-to-stock timeline should be provided. for PP Es, if the shortage cannot be so lved within a short period of time, they should be saved for those who truly need them includ ing medical professionals treating patients with COVID-19. All local medical supply businesses should tum in their inventories since the State Emergency has been declared. These timely updates will provide assurance to the public to avoid panic and chaos. NIH-000570 > > 5. Encourage online shopping and drive-thru pick-up including groceries. Help the local businesses to expand their delivering capacities. > > 6. Provide the public live updates on the outbreak , including the number of confinned cases , their curre nt clinical status, strategies of tracing their close contacts , as well as the number of tota l cases being tested. From what T have learned, the more transparent the government is, the less panic the public will be. > > 7. Issue laws that prohibit intentional spread of COVID - 19, irresponsible behaviors that put other innocent peop le or medica l professiona ls at risk of contracting the virus. > > > > For medical professionals : > > Early January in Wuhan, many patients very likely contracted CO YID- I 9 in the local hospita ls when they visited their physicians for other medical conditions. In addition, the medical system in Wuhan China was almost paralyzed at that time. One of major reasons is that many medical professionals were infected and sick. The medical professionals are the backbone in the fight against this vims outbreak . We need to prepare for the worst scenario that this outbreak can last for a few or several months. We need to protect om medical professionals first. > > I. Set up a centralized Fever/COYID-19 hotline operated by trained provider/nursing staff. This telephone line can use the current available state infom1ation hotline , with expanded functions serving as a gatekeeper and triage mechanism for potential COVID-19 patients to receive guidance on where to seek help before visiting a busy clinic , an urgent care , or a hospital emergency room to minimize the chances of cross-infection and over-whelming large medical centers. > > 2. Establish designated Fever/COVTD- 19 clinics or hospitals led by well-trained ID teams (MD , NP), especially in highly populated areas. These clinics will serve as the secondary triage and referral centers for the aforementioned Fever /COVTD-19 hotline, plus for primary care clinics that are not equipped with adequate staff and testing tools . These clinics should have adequate staff including physic ians and middle level providers, equipped with testing kits to perfonn COYID -19 test on site. They should have the capacity of testing drive-through patients , securing airway for ventilation if needed before transferr ing severe patients to tertiary medical facilities. They should be operated collaboratively with larger healthcare systems like U Iowa , Unity Point , and Mercy who are setting up their own isolated COVID-19 centers for more severe cases. > > 3. Establish a clear conunun ication and transfer protocol between Fever/COVID -19 hotlines, clinics and treating hospitals for management of suspicious and confirmed cases. For those with mild COVID-19 infection, they should be self-quarantined at home and monitored closely and remotely. If they cannot perform self-quarantine safely, such as living by themselves or in nursing homes, they should be kept in the county isolation facilities (as mentioned above), being monitored there. > > 4. If drive-through testing is available at CVS or Walgreen , patients with positive results should call the hotline or their PCPs first if clinically stable to receive guidance for self-quarantine , monitoring and follow-up. If they cannot perform self-quarantine safely , they should be kept in the county isolation facilities as mentioned above. > > 5. lnform the public and other healthcare providers of the availability of these Fever/COYID-19 hotline and clinics, encouraging patients with symptoms to utilize these resources first before visiting clinics , emergency rooms to reduce the chances of cross-infection , and the burden on large medical centers. > > 6. Encourage medical professionals to call their clinic patients for screening . Allow the medical providers to postpone all non-urgent medical visits for annual checkups , stable and non-urgent chronic conditions et al. > > 7. Encourage all physicians and healthcare professiona ls who provide direct patient care to wear personal protective equipment (PPE) such as masks, eye shields and gloves to protect themselves and to minimize the chances of spreading the virus to other patients, if necessary or based on their screening phone calls. NIH-000571 > > > > > > Sincerely, > > > > > > > > > > > > > Kind regards , ----------------------- -------Xiaoyang Hua, MD/PhD Duke Head and Neck Surgery > NIH-000572 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 15:08:54 -0400 Jon LaPook Re: TIME SENSITIVE;from Jon LaPook to Tony Fauci I would not use an age number, but if you had to I would say 70. I would say "serious" underlying condition. Not sure about ACE inhibitor s. On Mar 15, 2020, at 3:01 PM, Jon LaPook ------- CbH6l wrote: Tony, Since "elderly" means different things to different people (to me, it's 10 years older than me - and l' ~ hould I give a certain age after which people should voluntarily selfisolate now? And for underlying conditions, should I say "serious underlying conditions" or leave it vague at " underlying medical condit ions?" I think the more specific the bet t er. And, fina lly, I'm hearing that it's puzzling that hypertension is such a risk factor and that perhaps people on ACE inhibitors are upregulating receptors for ACE2 in the lung. Any evidence of that? If so, maybe we should switch people off ACE inhibitors for now. Thanks, Jon From: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Date: Sunday, March 15, 2020 2:46 PM To: Jon LaPook CbH6J> Subject: RE:TIME SENSITIVE; from Jon LaPook to Tony Fauci Jon: Looks quite good. I suggest that you lean out there and explicit ly say that the elderly and certainly those with underlying conditions should voluntar ily self-iso late now. Best regards, Tony ------- From: Jon LaPook (b)(6) Se nt: Sunday, March 15, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: TIME SENSITIVE; from Jon LaPook to Tony Fauci ------------- == Hi Tony, NIH-000573 I would like to post this widely today , but want your input first. Can you please make suggestions/add itions/correct ions? Thanks so much! Jon The World Health Organization has declared the Covid-19 outbreak to be a pandemic -- official recognition that the virus respects no borders and now affects masses of people in countries all over the world. And there is no denying the world is changing, in painful ways . We see it in financial markets, where prices are plunging -- and in supermarkets, where customers are stripping shelves bare. All driven by fear , as the number of virus cases grows with each passing day. While we may feel powerless over this threat, we are not. There are important things we can and must do -and right now . To borrow a phrase from the war on terror, the coronavirus only has to be right once to infect us. We have to be right every time to prevent it. So, every time you cough or sneeze , use a tissue or the crook of your arm. Every time you think of it, wash your hands -- as frequently as you can. Every time you can, practice "social distancing" -- stay away from others during this outbreak. Social distancing is now being enforced throughout our society. Schools are closing, sporting events of every kind are being canceled. The curtain has even come down on Broadway shows as the Great White Way goes dark. Despite our best efforts , it's likely many of us will eventually get infected by the virus , since we have no immunity to it. If that's the case, you may ask, does it really matter when we get infected? The answer is a resounding yes! And here's why: slowing the spread of coronavirus -- and consequently delaying infections -- can make an enormous difference in our ability to handle the pandemic . Take a look at this illustration. It appeared in the Economist and is based on a CDC report . The blue curve shows what happens when you do nothing . The number of infections peaks relatively quickly. This can overwhelm a healthcare system that is not prepared to handle such a huge number of patients. Emergency rooms and hospitals can become overloaded. We may see shortages of medical supplies -- including protective gear and breathing machines -- and shortages of healthcare workers, especially if many of them become infected. But look at the yellow curve. It shows what can happen when you slow the epidemic. The outbreak is stretched out. And while it may last longer , the peak number of infections is much lower, putting less stress on the healthcare system and allowing better care for each patient. It also gives scientists more time to develop new treatments and vaccines . NIH-000574 Is there any evidence this works? Absolutely, especially when coupled with the time-proven technique of aggressive testing to find and isolate infected people as early as possible. In China , where there has been strict quarantine and social distancing in the epicenter of the outbreak, new infections have dramatically slowed. In South Korea, where health officials cleverly used drive-through testing, we' re also seeing the number of new cases slow down. And there 's a history lesson from the 1918 flu pandemic . Back then , Philadelphia held a parade attended by several hundred thousand people. Soon , every hospital bed in the city reportedly was filled with sick patients . Saint Louis , on the other hand , practiced social isolation and saw fewer cases. So we have work to do, and it won't be easy, because it means changing the way we live our daily lives and how we interact with our neighbors . And we have to start now -- when we can make the most difference . And here's something we need to keep in mind. We are all in this together. So even as we keep a distance from each other physically , we need to stay close emotionally. Social isolation is bad for your health! If ever there was a time to call or video chat with friends and loved ones. And don't forget to reach out to the elderly --who may be alone and afraid. Demonstrating grace under pressure is easier said than done. But that is this doctor's prescription for getting through this . And , if we treat each other with kindness and empathy, we will. Jonathan LaPoo k, M .D. Chief Medical Correspondent, CBS News Prof essor of Medic ine NYU Langone Health PLEASE NOTE: IF YOU LEAVE ME A MEDICAL MESSAGE AND DO NOT HEAR BACK WITHIN 24 HOUR S, PLEA SE CALL MY OFFICE AT 646-754 2000 . PLEASE NEV ER LEA VE AN EMAIL ABOUT AN URGENT MEDICAL ISSUE. This messageis confidential. WARNING : THIS EMAIL MAY CONTAIN CONFIDENTIAL MEDICAL INFORMATION The medical inform ation in this message is confidential and privileged. It is unlawfu l fo r unauthor ized persons to review, copy, disclose or disseminate confidential information . If the reader of th is warn ing is not the intended email recipient , or the intended recipient 's agent, you are hereby notified that you have received t his email in error and that review or furth er disclosure of the information contained NIH-000575 therein is strictly prohibited. If you have received this email message in error, please notify us immediately at 646-754-2000 and delete the original message. HIPAA regulations require proxy/patient approval before use of electronic media. By requesting and/or agreeing to email correspondence, you are agreeing to use of electronic media for transmission of info rmation. NIH-000576 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:52 -0400 To: Liz Subject: Re: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it's own epidemic . Good point > On Mai 15, 2020, at 2:42 PM, Liz_______ (b _.).,.(6) _.. wrote: > > Hello Dr. Fauci , > > T hop e you will see thi s m essage. T he subject line is part of th e eq ua tion , for Covid - 19, in th e US whi ch is an unknown . Tam highly concerned how ft will affect this group. Please let all hea lthcare systems know to be awa re and have thi s on their radar. We keep hearing it's for older adults but it's for people with co mpromised lungs among other all pre -existing conditions you've mentioned. > > Sincere ly, > Lyzzy Crouse NIH-000577 From: (b)(6) Date: Sun, 15 Mar 2020 15:02:32 -0400 To: Schuchat, Anne MD (CDC/OD) Subject: Fwd: Concern for young 'Vapers' population; th is will be serious for them. Vaping was already it's own epidemic. This pe rson makes a good point. Beg in forwarded message: From: Liz (bH > Date: March 15, 2020 at 2:42:24 PM EDT To: "Fauci, Anthony (N IH/NlAID ) [E]" (b)( · Subject: Concern for young 'Vapers' population; this will be serious for them. Vaping was already it' s own epidemic. --------=-=--:= Hello Dr. Fauc i, I hope yo u will see this message. The su bject line is part of the equation, for Cov id19, in the US which is an unknown . I am highly conce rned how It will affect this group. Please let all heal thcare sys tems know to be aware and have this on their radar. We keep hearing it's for older adults but it's for people wi th compromised lun gs among other all pre-existing condit ions yo u 've mentioned. Sincerely, Lyzzy Crouse NIH-000578 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 15 Mar 2020 18:33:06 +0000 Eisinger, Robert (NIH/NIAID) [E) FW: Tools that may help you To: Subject: Please handle. ------------- From: Landrigan, David Date: Sunday, March 15, 2020 1:44 PM To: Fauci, Anthony {NIH/NIAID) [El -------~= (b)(6) (b)(6) --------- (b)( >; Fauci, Anthony (NIH/NIAID) [El Subject: Tools that may help you Tony, It has been about 20 years since you and I talked about SARSand my model that David Will iams at WHO used. I didn't know if your old email still worked, so I'm using the directory listing by NIH in addition. I have some ideas to share with you about the use of tools in the current war on covid-19. Your 'close the bars' statement is right on target with what I was writing when I heard you say it . It was a great illustration counterintuit ive to what will work . You could have more correctly said keep the bars open on ly to those in their twenties and thirties. Five minutes later Mayor DeBlasio said everything is on the table including closing bars and restaurants! Below you will see me argue why there are better approaches and this total closure approach is the wrong move. Selective participation will work in our favor to blunt the curve! Total closure will not work and can wo rk against us! In a period of two weeks demand for medical treatment can go from 50% of hospital capacity to 200% due to disease progression and binomial expansion. You know the math and ideas, so there's no need to go into them. There is a need to closely consider how available tools are being used to mitigate an overwhelm ing of the health care system. I can tell you now that what needs to be done isn't being done and that the road we are on now will at most postpone crossing the threshold of 100% capacity. It will not achieve the desired result of distributing cases over a greater time period so that being overwhelmed is avoided . Consider the curves: The ' with out protective measures' curve is the normal distr ibut ion as modeled by the binomial distribut ion. The 'w ith protect ive measures' distribution is what we want to achieve, although that would be fore ign to an exper imenta list. We don't want the number of cases to exceed capacity as indicated by the horizontal dotted line. If the 'protective measures' are social distancing, school closings, entertainment/sporting cancelations, restaurant closings, and hygiene and similar uniformly applied measures, the 'with' curve should have a shape similar to the 'without' curve, just shifted to the right, unless there is some unpartitioned factor interaction. The flattened curve WILL NOT RESULTbecause errors should be random and SAMENESSOF TREATMENTPRODUCESSAMENESSOF EFFECT.With UNIFORM application of measures the curve afte r application will still exceed a height showing the system capacity has been exceeded . NIH-000579 We could expect to flatten the mesokurtic 'without' curve into the platykurtic 'with' curve by systematic time staggering in the use of the protective measures and selectively apply ing the measures to drive toward herd immunity. As immunity builds toward HIT (Herd Immunity Threshold), there will be greater and greater slowing of infections as the linkages for transmission decrease. There are two points to consider here. The first point is whether measures should be applied in a uniform and blanket manner. The answer is typically no when the effect is on an existing population because the curve won't flatten. There are two aspects of the application of measures to consider. Is the effect of the application defining the population or is it an effect within a defined population. In the instance of halting all air traffic to the US from China, the population is being defined and altered if influx is allowed and that would both increase the infections and population turbulence. There would be movement away from HIT. Any measure such as people influx, which moves the US away from HIT, is to be avoided. School, restaurant, and sporting event closings need to be examined in relationship to their impact on an existing, not an increasing population . The actions have many criteria to influence them, but from the viewpoint of keeping the healthcare system from becoming overwhelmed closings that are staggered, variable, and alternating will work to increase movement toward HIT and promote flattening of the 'with' curve. The second point to consider is whether we can move the US toward HIT by age selective application of available measures. The answer is yes and this could provide the best tool. Susceptibility and strengths of covid-19 infections covary with age. People less than 30 rarely have severe infections and the younger ones may not become infected. People under 40 show a low frequency of severe infection. It will be important to know if there is a large age cohort exempt from infection because that would undermine part of the result from selective app lication of measures or limit the sampling age because these people wouldn't develop immunity , but might contribute to delaying herd effects. If they develop immunity their contribution can be substantial and they can be kept separated from more vulnerable people until and unless it is established that there isn't a need. Opening night clubs, sporting events, restaurants, and other places to people in their twenties and th irties will build immunities, break infection transmission links, and move toward HIT with little or no risk to the people or the rest of the herd. Have admission to the venues by existing ID, like a driver's license with age, and have agreement that they do not mingle with vulnerable older people. Leaving the bars open to people in their 20's and 30's will flatten the curve! NIH-000580 From: Fauci, Anthony (NIH/NIAIO) [E) Sun, 15 Mar 2020 18:32:34 +0000 Birx, Deborah L. EOP/NSC RE: [EXTERNAL ] CNN question/German vaccine company? Date: To: Subject: This is the first that I have heard anything about this subject. From: Birx, Deborah L. EOP/NSC (b)(6)> Se nt : Sunday, March 15, 2020 1:38 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b) '""' (= 6)> Subject: Fwd: [EXTERNAL]CNN question/German vaccine company? Do you know anything about this? Sent from my iPhone Begin forwarded message: From: "Miller, Kat ie R. EOP/OVP" (b)(6) Dat e: March 15, 2020 at 1:14:28 PM EDT ---------~~ To: "Birx, Deborah L. EOP/NSC" (b)(6J> Subject: Fwd: [EXTERNAL] CNN questi on/ Germ an vaccine comp any? Sent from my iPhone Begin forwarded message: From: "Liptak, Kevin" Dat e: March 15, 2020 at 1:09:32 PM EDT To: "Miller, Katie R. EOP/OVP" (b)( >, "Fetalvo, Ninio J. EOP/OVP" (b)(6J>, DL NSC Press (b)( > ----------=-~ Subject: [EXTERNAL] CNN questi o n/ Germ an va ccine company? Afternoon - checking to see whether the White House has any comment on these allegations in German media that President Trump is offering large sums of money to lure a German vaccine maker to the United States? >https://www .reuters .com/art icle/us -health -coronav irus-germany usa-idUSKBN2120IV< Thanks Kevin NIH-00058 1 KevinLiptak CNN White House (b)(6) NIH-000582 (bX5) - PCl1 NIH-000583 (bX5)-PCI NIH-000584 NIH-000585 NIH-000586 From: Date: Sun, 15 Mar 2020 13:30:08 -0400 To: Soumya Jayaraj Subject: Re: Concern about Covid spread in South Padre Island Texas (b)(6) Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at l :29 PM, Soumya Jayaraj ---------- CbH6)wrote: Hello Dr . Fauci , I hope you get to read this and you can do someth ing about it. I am wr iting from Cb)~. Here at South Padre Island spring break events are going in full swing with no concern whatsoever about coronavirus spread. We do not have positive cases yet in the Rio Grande Valley but this is inviting the disease here. ------ People come from all over USA , especially students in huge numbers for spring break to SPI. In spite of repeated requests by pre ss and general public the authori tie s have not shut down the event. I am attach ing a couple of articles below . It is very concern ing to see the author ities do not seem to understand the gravity of the situation and the importance of social distancing which is the need of the hour. Kindly look into this and please do what you can to put a stop to this. Please note the crowd is expected to increase next week. Appreciate your help. Thanks Regards Soumya Jayaraj https://ww w.them onitor.com /2020/03/ 12/ sp i-spring-break-con tinue/ https://www.facebook.com/KRGVChris tian/v ideos/ 1954047085687 68/ NIH-000587 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 13:29:23 -0400 Daphne Coley Re:Confidence in you Thank you for your note A.S. Fauci. Sent from my iPhone _______ .... > On Mar 15, 2020, at 1:22 PM, Dap hne Coley (b) ( wrote: > > Dear Dr. Fauci. > > Out of this whole mess you are the voice of reason that is most comforting. Your intelligence , calm demeanor and lack of p ersonal agenda (I hope) come through in your explanations of this recent crisis. > > I have read how many lives that you saved during the AIDS crisis and Laude you for it. I trust, given enough rein, that you can do it for the COVID-19 crisis. > > You must be feeling the weight of crushing political and media forces_ a real tightrope. Then, of course you do have to worry about the illness itself, which should be your primary concern but might be probl emat ic given the infig hting and > terri torial nature of politic s. > > Anyway , I wanted you to know that you have a real fan in (b) (6) . If there are two there are many , many more . .lust keep on doing what you do so well and know that you are appreciated by lots of American s. > > Best, > Daphne Coley NIH-000588 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 13:28:26 -0400 rclavalle Re:Thank you! Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 1:25 PM , rclavalle -------- (b)( >wrote: Good afternoon Sir, Thank you for your continued vigilance in protecting the American people. Your wise guidance regarding a temporary national lockdown may greatly help in reducing the spread of COVID-19. If this action were to occur it should be in phases: Phase 1: Federal Quarantine. Effective Immediately until 4 MAY 2020 (or further notice) - ONLY Key and Essential federal employees of all agencies (IC included) should repo1t to work. Eve1yoneelse is on administrative leave. While buildings are empty, staff remaining should conduct deep cleaning (air systems, etc.) to ensure a healthy environment when employees come back to work. Pha se 2: Federal recall: Be ginning 4 MAY 2020, federal employees are called back to work on an as-needed basis (indefinitely) depending on how the virus trends. Excluding postal workers, that accounts for nearly 2 million full-time employees. There should be a mandatory home-quarantine so people are not out spreading the disease. Phase 3: Mitigation and recovery. Federal agenc ies need to produce mitigation measures (crisis action plans) should something of this nature occur in the future. F ederal agencies must be ready to respond in an organized manner when a cn s1soccurs. Throughout this COVID-19 event, military and law enforcement must have an increased presence to prevent mass hysteria and mob mentality. Increased military and law enforcement presence may help enforce the home quarantine measures and prevent looting and other crimes that tend to occur during crisis events. NIH-000589 The National messages may include the following: The top priority is the safety and security of the people We will make decisions based on health guidance and current conditions here and elsewhere We will get through this together (share resources , express kindness etc.) We need to care for each other - It is vital it is to unite around this crisis As a Nation , we need to come together as a conununity to survive this international disaster This health crisis is challenging each of us to make sacrifices and implement changes out of the norm. Ultimately , this crisis is not about us. It's about our responsibility to each other. Thank you for all you are doing during this difficult time. Thank you, Sir, for taking the time to review this corres pondence . Best regards , RC La Va lle-McIntosh NIH-000590 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:21:50 -0400 Laetitia Moreau Re: Alert: ADVIL= killer with COVID19 , references and more Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020, at 1:16 PM, Laetitia Moreau Cb)(6J>wrote : Est imated docto r Fauci Wi t h covi d t he r e ar e dos and don' ts. An important DON' T f i rst and a DO he r e I heard fr om Fr ance and Eur ope. USAto be advise d . Self medication / Unecessary medication of Advil &corticoids is highl y dangerous with Covid 4 young adults were in critical conditions in France with no special reasons except they self medicated on Advil https : //www.theguardian.com/world/2020/mar/14/anti inflammatory - drugs - may- aggravate-coronavirus infection?CMP=share btn tw In French news https : //www.lefigaro.fr/sc i ences/coronavirusalerte-sur l - ibuprofene - et -autres - anti - inflammatoires - 20200314 French people directly avoid Advil https://twitter.com/ol 264 instructed by Health Minister i vi erveran/status/1238776545398923 Reference articles https://www.thelancet.com/action/showPdf?pii=S2213 2600%2820%2930116-8 NIH-00059 1 - to htt 40- www . t hel an 20 30317- 2 ourna l s lancet artic l e PIISOl Also about oo. I have been sharing about s leep / mor ning sun and covid. Sleep protects against virus. we should keep standard time permanently. A good move alreaqy in normal times. covid is an additional reason. https: // www.ucsf. edu{news/ 2015/ 08/ 131411/ short - sleepers are-four - times-more- ikely - catch - cold https ://www.ncbi.nlm.nih .gov/pubmed/26118561 "The impact of daytime light exposures on sleep and mood in office workers ." High levels in the morning is associated with reduced sleep onset latency ... and increased sleep quality . ncbi.nlm.nih.qov/oubmed /2852625 Thank you for your work. Laetitia Moreau (b)(6) <> NIH-000592 From: (b)(6) Date: Sun, 15 Mar 2020 13:19:05 -0400 To: (b)(6) Subject: Re: Suggestion for the Coronavirus Task Force Thank you for your note A.S. Fauci. Sent from my iPhone On Mar 15, 2020 , at 12:05 PM, wrote : --------- (b)(6) Dear Director Fauci, While important stores with pharmacies (Walmart, CVS, Walgreens) remain open, many elderly folks are afraid to enter due to the mixing of young and old and the increased risk of coronavirus exposure. I suggest that these stores designate certain hours for for those 60 years of age and older. Now that stores are reduc ing hours to clean and restock the stores overnight, the best hours might be first thing in the morning . For example for Walmart , the hours designated for those 60 and over could be 6 a.m. to 9 a.m. This could reduce their exposure to younger people who might have the virus but who are asymptomatic (or relatively so) . This same idea could be applied to grocery stores. Best wishes Alan R. Ertle MD MPH, MBA (b)(6) NIH-000593 From: Date: (b)(6) To: Subject: Sun, 15 Mar 2020 13:17:01 -0400 Herb Re: Coronavirus Thank you for your note A.S. Fauci . Sent from my iPhone On Mar 15, 2020 , at 12 :24 PM , Herb ----------- CbH6) >wrot e: (b)(6) I feel that the information I have might be of interest to your posit io n in this matter . If so, please reply by return email. Thank you. Herbert E. Johnson Sent from Mail for Windows 10 NIH-000594 From: (b)(6) Date: Sun, 15 Mar 2020 12:02:05 -0400 Conrad, Patricia (NIH/NIAID) [E) Fwd: Request for interview To: Subject: Sent from my iPhone Begin forwarded message: From: Larry Milian < lmilian @slammiami.com > Date: March 15, 2020 at 10:42:39 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Cc: Larry Milian -------- --;;-~ (b)( Subject: Request for interview Dr. Fauci, My name is Larry "The Am igo" Mi lian and I am the Nationa l General Manager and Progra m Director for SLAM Radio on Sirius XM 145. I would like to respectfully request to have you on with me on my national morning show to update and discuss Coronavirus. I will be on air tomorrow starting at 7am est. While my show normally ends at 11am, [ have decided to stay on air in order to keep our listeners properly infom1ed. I would like to thank you in advance. Kind ly email me or ca ll me back (b) (6) ~ ) and let me know what might be the best time to come in the air with me . LaITy'The Amigo " Milian National GeneralManager/Program Director SLAM Radio on Sirius XM - Channel 145 LMilian @SLAMMiami.com (b)(6) NIH-000595 From: (b)(6) Sun, 15 Mar 2020 11:57:49 -0400 Alex Tanner Re: Nasal spray Date: To: Subject: Thank you for your note. A.S. Fauci Sent from my iPhone > On Mar 15, 2020, at 11:56 AM, Alex Tanner > > Greetings Dr. Fauci: > ------------ (b)( > wrote: > Wouldn't some concoction/ratio ofbleach to water put in a nose spray bottle help prevent or kill covid-19? What about hydrogen peroxide? > > Regards, > Alex > > Char les A Tanner (b)(6) > > Sent from my iPhone NIH-000596 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 11:57:34 -0400 Deborah Lowery Re: Hospitalization of covid-19 positive patients Thank you for your note. A.S. Fauci Sent from my iPhone --------- > On Mar 15, 2020 , at 11:57 AM , Deborah Lowery (b)(6) wrote: > > Eve ry large US city has several hospitals within city limits . Would it be possible to set up at leas t one hospital for ONLYcovid - 19 positive pa tients requir ing hospitalizat ion. This cou ld belp prevent transfer of virus to those hospitalized that do not have the viru s and could help reduce the need for more personal protective supplies needed for staff, since only thos e staff at that particular hospital would be taking care of those with covid- l 9. Thank You for your time. > Deborah Lowery NIH-000597 From: Date: (b)(6) To: Sun, 15 Mar 2020 10:17:01 -0400 Esam.Almarzo uq Subject: Re:God blessyou all Thank you for your kind note. > On Mar 15, 2020, at 10:13 AM , Esam.Alrnarzouq wrote: > > Dear D r Anthony > > My name is Esam AIMarzouq from (b) ~ a country that Jam sure you know. My daughter is studying in one of the un iversit ies in (b) (6) > > I ju st wanted to take the oppo 1tunity to say God bless you for all the effo11taken by you along with your colleagues in NIAID and President office to contain Corona Virus. I am confident, with God he lp we sha ll all overcome Covid-19 pandemic. > > All the best wishes to you all > > Regards > Esam AlMarzouq > CEO - JS GROUP, private company in the area of general trading and construction in Kuwait NIH-000598 From: Date: To: Subject: (b)(6) Sun, 15 Mar 2020 09:28:21 -0400 Mary Lane Re: Honest Communication Than.ks! > On Mar 15, 2020, at 9: 17 AM , Mary Lan e > --------- (b) (6)> wrote: > Thank you so much for being hone st about the coronavinis. We feel we can trust what you say! > > Sent from my iPhone NIH-000599 From: (b)(6) Date: To: Subject: Sun, 15 Mar 2020 09:15:29 -0400 NIAID Public Inquiries Fw d: Ind igenous Peoples - Bat Guano Harvesters - COVID-19 Sent from my iPhone Beg in forwa rded message: From: Geoffrey Wilcox (b)(6) Dat e: March 15, 2020 at 9:11:50 AM EDT ,-------;;-c-;= To: "Fauci , Anthony (NIH/NlAID) (E]" (b)( Subject: Indigenous Peoples - Bat Guano Harvesters - COVID-19 Dear Mr Fauci: Is it poss ible to be immune to the virus? W hat if any research has been done on the indigenous people around the world, including the US, that have harvested guano for centuries? Geoff Wilcox NIH-000600 From: Date: To: Subject: Attachment s: Fauci edit.docx Fauci, Anthony (NIH/NIAID) [El Sun, 15 Mar 2020 01:58:46 +0000 Collins, Francis (NIH/OD) [El RE: Draft all hands message Draft_AII_Staff_F irst_NIHStaff_Coronavirus_3 .14.20_ V2 fsc clean - with minor Francis: It looks fine, but I made one minor edit that is tracked. Thanks, Tony From: Collins, Francis (NIH/OD) [E] Date: Saturday, March 14, 2020 9:38 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Cc: Tabak, Lawrence (NIH/OD) [E] Subject: Draft all hands message ------- (b)(6)> (b)(6)> :;.::::======~-,-=, --------- (b)(6) Hi Tony, If you have a couple of minutes to review it, please let me know if you see any problems wi t h this draft all-hands message. FC NIH-00060 1 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [E) Sun, 15 Mar 2020 01:11:43 +00 00 Robert Jones RE: Avoid ing Italy 's Coronaviru s Disaster Thank you for the note. From: Rob ert Jone s (b)(6) Se nt: Saturday , M arch 14, 2020 8 :26 PM To: Fauci, Anth ony (NIH/ NIAID) [E] -------=- (b)c-c (= > Subject: Avoid ing Italy's Coro navirus Disaster Dear Or. Fauci, Thank you for your leadership. I ask that you take two minutes to read the following artic le in today's Boston Globe written by an Italian journalist. https://www .bostonq lobe .com/2020/03/ 13/ opin ion/coro navirus-ca utionary-ta le-italy-dontdo-what-we-did/ Bottom line: Please consider a lockdown or some form of a lockdown by the end of this week. Best regards , Bob Jones NIH-000602 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Sun, 15 Mar 2020 01:00:13 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Covid 19 Minocycline From: Ramaswamy,Sriram Date: Saturday, March 14, 2020 9:00 PM To: Fauci,Anthony (NIH/NIAID) [E] -------=Subject: Covid 19 Minocycline (b)(6) ------------(b)c-c (= > Hi Dr. Fauci, Pardon the intrusion into your email. I am sure you are super busy spearheading t he fight against COVID-19, hence I will cut to the chase. If your research team is looking for ideas to manage this novel virus, perhaps you can consider adjuvant minocycline. Personally I conducted a sma ll proof of concept study with minocycline in veterans with PTSDand am now collaborating with the San Francisco VA for a larger and definitive study. The point I am making that minocycline has potential benefits beyond antibacterial .. I see that the re is preliminary evidence that it can slow down viral replicat ion. Anyway you are the international expert and we all THANK YOUfor all that you do! Best, Sriram Ramaswamy, MO Professor of Psych1alry Vice Chair for Research Department of Psychiatry Creighton University School of Medicine 7710 Mercy Road,Suite 601 Omaha, Nebraska 68124-237 NIH-000603 From: (b)(6) Sat, 14 Mar 2020 19:24:11 -0400 Fabien Re: Great talk, as usual ... Date: To: Subject: Thank you for your note . A.S . Fauci. Sent from my iPhone On Mar 14, 2020, at 3:42 PM , Fabi en --------- CbH >w rote: Dear Professor, We see you every where at telev ision in France currently . I fully understand that you have much more urgent to do than answe ring my previous email and 1 apologi ze to have bothered you. Bon courage ... With all my respect and admiration , for decades, Fab ien Sordet. Envoye de mon iPhone Le 10 mars 2020 a 19:09, Fabien --------- Cb>< a ecrit: Dear Professor Fauci, Great talk at CROI... Thank you. I follow your works on HIV for 25 years. (b)(6) when I stated to work on HIV myself. This give me the chance to have your email address, but it is not as health care professional that I write you today . Just as human, lambda human ... My parents are a bit older than you . Imagine fo r yourself : If tomorrow, whereas you are already vaccined against Flu, yo u have significative start of feve r and cough, in an environment ----- NIH-000604 where Covid-19 is epidemic, would you right away take Kalet ra and Plaquenil (knowing the fact that if there is a little chance it works, the soonest is the best) ? Kind Regards, (b)(6) NIH-000605 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:23:16 -0400 Janice Strauss Re: Truthful science information Thank you for your note. A.S. Fauci. Sent from my iPhone (b) ( > wrote: > On Mar 14, 2020, at 4:04 PM, Janic e Strauss > > Dr.Fauci. > > Thank you for your determ ination and stamina to infonn the American public with science-based upda tes and information regarding the novel coronavirus . > > Without the appropriat e data the virus trajec tory will leave the country in a state of greater uncertainty and fear. Among many of the public who watch the task force briefing s you rema in a bulwark against chaos and panic. ---------- > > When politicians announce policy regard ing the virus they may fear accusations of"flip flopping" when a fluid situation requires nimbleness through recalibration or reversal. That instinct is not party-based. However , an honest, neutral agent eschewing disinfom1ation, misinforma tion, or omissions might better protect the public than a politician concerned with polls , contributions, and election results. > > Thank you, Dr. Fauci, for being the honest, neutra l agent despi te direct or untoward pressure to ignore sciencebased evidence. > > Sincerely, > Janice Straus s > > > NIH-000606 From: (b)(6) Date: Sat, 14 Mar 2020 19:22:43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost wit h potential ly greater potency Pis respond Sent from my iPhone Begin forwa rded message: From: Mark Emalfarb (b)( · Date: March 14, 2020 at 4:11:01 PM EDT To: "Fauci , Anthony (NIH/N lAID ) [E]" (b)(6) Subject: Helping to mass produce more dosages of cornavirus vaccines and antibodies at lower cost with potentially greater potency -------=~ Dear Dr. Fauci I don't want to overburden you with a long e1nail, so I'll try and get to the point. First, we have developed a gene expression system, our C 1 cell line which is significantly more efficient than traditional cell lines being used by Big Pharma to manufacture recombinant vaccines and drugs . The hyper produc tive Cl cells can be grown at flexible commercial scales and are proving to be the most efficient, cost effective way to produce the tens of millions of preventative vaccine s and/ or antibody treatments the world so desperately needs. In a collaborat ion with Sanofi, C 1 cells were developed to produce recombinant proteins for use in manufacturing a lower cost better performing influenza vaccine. After conducting a NIH-000607 mice trial Sanofi concluded that the use of our Cl platform resulted in equal or better influenza protection, using a lower amount of vaccine that could be produced at 10-30 times higher productivity levels. The Original Sanofi Presentation can be found at the following link: https: //www.dyadic.com/wp -content/up loads/2018/01/Sanofi Pasteur -C 1-Presentation.pdf (b) (4) Wor king togethe r we can "Keep America Safe" by helping to addre ss the immediate coronavirus outbreak , be better prepared for future infectious diseases, pandemic, and epidemic outbreaks, and leveraging this unfortunate situation to advance biopharmaceutical manufacturing to help speed development, lower the cost and improve the performance of NIH-000608 biologic vaccines and drugs such as insulin, seasona l flu and other vaccines and antibod ies to make healthcare more accessible and affordable to patients. I am confident that a meeting with you can be very productive in further stimulat ing big pharma and other research institutions to speed effective, low cost vaccines and antibodies to market. Given the severity of the current coronavirus situation, I am prepared to make myself available for a meet ing at your convemence. My cell number is quickly. ----- CbH6) should Sincerely, Mark Emalfarb Chief Executive Officer Mark Emalfarb CEO Dyadic International, Inc. CbH6)(Office) CbH6)(Cell) www.dyad ic.com ------ NIH-000609 you want to reach me From: Date: (b)(6) Sat, 14 Mar 2020 19:21:17 -0400 Richard Lynn Re: So proud To: Subject: Thank you for your note. A.S. Fauc i. Sent from my iPhone On Mar 14, 2020, at4:41 PM, RichardLynn ----------- CbH6) >wrote: So well said Carol. Be we ll Richard Richa rd A. Lynn, MD ,FACS ,RPVI (b)(6) On Fri, Mar 13, 2020, 5:23 PM Carol Storey-Johnson wrote: Dear Dr. Fauci-I fully agree with Dr. Lynn's message. I have been following your commentary on the current COVID-19 pandemic. Our Dean, Dr . Augustine Choi, has also been a major positive voice at WCM, communicating frequently with our community and, in his role as an expert in pulmonary diseases, echoing your messages at WCM as we struggle to educate students and trainees and manage the overwhelming questions and administrative issues that present themselves at this time. The measures he has implemented at WCM have been scientifically sound and commensurate with national expert (yours included) recommendations . As a member of the Board of Directors of the Alumn i Association, I am also so proud of your work in t his critical time for our nation. I'm sure WCM is appreciative of your representing the quali t y of your train ing, career experience , scient ific thinking, and academic acumen in your advice to the nation and its people in these challenging times. The Alumn i Association has recognized your work in the past, but your continued efforts speak so well to the excellence in the rigor and standards of the NIH-000610 educational, research, and clin ical experience that all of our alumni have had at WCM. We wish you well and hope that you have continued influence in these matters. Sincerely, carol Storey-Johnson MD Professor Emerita of Medicine Weill Cornell Medical College Note: This information, transmitted from Weill Cornell Medical College, is intended only for the person or entity named above, and may contain legally confidential and/or privileged material. Any forwarding, copying, disclosure, distribut ion, or other use of this information by any person is prohibited . If you are not the intended recipient, any review or taking of any action in reliance upon this information is strictly prohibited. If you received t his in error, please contact the sender and dele te the material from all computers. Thank You. From: Richard Lynn (b)(6)> Date: Tuesday, March 3, 2020 8:22 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: nl121 ; Natasha I Leibel ; kathleen foley (b)(6); Carol Storey-Johnson ; Lewis M Drusin Subject: [EXTERNAL]So proud Dear Tony, As a member of the Board of Directors of We ill Cornell Med Alumni Association, J am so proud of what you are doing and proud that it all started in Olin Hall and 1300 York Ave . Drs McDermott , Hook , Kilbourne, Kean and Johnson must have great prid e in how you are a voice of science and reaso n during this crisis. Stay strong and thank you Ric hard 1(6) Ric hard A. Lynn, MD,FACS ,RPVI (b)(6) NIH-0006 11 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 19:19:57 -0400 Jim Edwards Re: Nitrile gloves request for COVID19 Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:49 PM, Jim Edward s (b) (6) wrote : > > > Dear Dr. Fauchi: > > Regard ing testing by drive through cars ,_______________________ > > It has been hard for me to grocery shop during this corona virus illness because the retailers are allowing the employees and baggers to (b) ( > (b)(6) > l so wish you could address this for u > > You do no t know how much this would mean to me. > > Thank you for your service! > > Best Regards, > -------- > > > > NIH-000612 (b_)_(6) _, From: (b)(6) Date: To: Sat, 14 Mar 2020 19:19:29 -0400 Norm Harris Subject: Re:Thank you VERYVERYmuch Thank you for your note. A.S. Fauci. Sent from my iPhone --------- > On Mar 14, 2020 , at 4:51 PM, Norm Harris (b) ( > wrot e: > > > For your recent frequent, focused , knowledgeable and unde rstandable asse ssments and recommendations regarding the COVID-19pandemic. > > A clear and transparent voice makes a very pos itive difference . > > Thank you, > > Linda and Nonn Harris > (b) (6) NIH-0006 13 From: Date: (b)(6) Sat, 14 Mar 2020 19:18:47 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Our Company Offer of Assistance During this Critical Time of the To: Subject: Coronavirus. Pis hand le. Sent from my iPhone Begin forwa rded message: From: Kay Savio Cb>lii b Date: March 14, 2020 at 4:59:41 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Cc: "Auchincloss, Hugh (NIH/N IAID) [E]" "McGowan, John J. (NIH/NIAID) [E]" ________ _ Subject: Our Company Offer of Ass istance Dur ing this Critical Time of the Coronaviru s. ---------::-,:-:-=--~~ Dear Dr. Fauci: I work for Focus Pointe Global, a Schlesinger Group Clinical Research Company that has a data base of over 6 million participants globally. Our company is the largest of its kind in the world. I wanted to reach out to the NIH &N IAID to see if there is any way our company can be of help during the coronavirus epidemic. We have the unique ability to survey this panel of participants on line or in person, asking various questions getting data back fairly quickly (approximately 2 weeks). Our company utilizes industry leading techniques and can follow this group for years in the future. We have worked with the NIH, CDC&such institutions as Northwestern University, Stanford, Harvard, Battelle, NORC, ICFetc., for many years. Please contact me if this is of interest and our company can be of help. Kind Regards, Kay Savio VP Client Development &Clinical Research FocusPointe Global - A Schlesinger Company ___ Cb _H_6) I .Fnr GFGlobal ocusPointe (b)(6) NIH-0006 14 - Qualitative &Quantitative Solutions ~~ ., I Visit our website , Growing& Innovating SCHLESINGERLearning GRO P People,Pass10& Pu pose NIH-000615 From: (b)(6) Date: Sat, 14 Mar 2020 19:16:32 -0400 To: NIAID Public Inquiries Fwd: COVID-19 reporting Subject: Sent from my iPhone Begin forwarded message: From: G C (b) (6) Date: March 14, 2020 at 5:18:16 PM EDT ,------To: "Fauci, Anthony (NIH/NlAID ) (E]" Subject: COVID-19 reporting -------- --;;-~ (b)( In VA, there is a woman who says she had "the corona" back in November and her husband had it in Decembe r. If this is fact, how can we trust om government when it comes to Public Hea lth? Sent from my iPad NIH-000616 From: Date: (b)(6) To: Subject: Attachments : Sat, 14 Mar 2020 19:15:18 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL PastedGraphic-10.tiff, ATTOOOOl.htm Pis respond. Sent from my iPhone Begin forwa rded message: From: "Prof.Shimon Slavin" Date: March 14, 2020 at 5:36:53 PM EDT To: "Fauci, An thony (NIH/NlAI D ) [E]" (b)(6) --------=-=--:= (b)(6>f Subject: Proposal for new treatment of established COVID-19 - CORRECTED EMAIL I APOLOGISE FOR SOME TYPOS IN MY PRE VIOUS EMA IL SENT TO YOU OUT OF SPONTANEOUS ENTHUSIASM. PLEASE CONSIDER THIS CORRECTED VERSION INST ED. Dear Dr. Fauci, You may not remember but we have met years back when I was at Stanford University and Training with the late Donald E Thomas to cons ider cell therapy of HIV based on the use of reduced intensity , non-mye loablative conditioning in preparatio n for stem cell transp lantation to induce tolerance and then apply cell therapy with donor lymphocytes wh ich I have proposed for consideration of treatment of patients with HIV wit h secondary malignancy. The purpose of this email is to try and capture your attention in order to consider a new treatm ent option for COVID-19 that can be applied for patients in need with evidence of disease with no delay. Whereas many companies focus on development of anti-corona vaccine, I believe the more rational approach should be to develop treatment for COV ID-19 and then, if the virus will be deleted and/or the disease controlled or modified, vaccination will result without the need for specific corona-specific vaccination which is not yet available and by the time it may be available it may no longer be relevant. I am serving as the Medical Director of a company in Hungary and we believe that one simple and safe experimental treatment of patients with existing viral disease may already be at hand, (bH 4J NIH-000617 (b) (4) I will greatly appreciate if you could give me a call or have one of your colleagues contact me and then I will be able to discuss the concept in greater details , after I will provide supportive scientific and clinical literature. I am available 24/7 on my mobile phone listed below. Shimon Slavin, M.D. Professor of Medicine Scientific &Medical Director , Biotherapy International The Center for Innovative Cancer lmmunotherapy &Cellular Medicine Weizmann Center, 14 Weizmann Street Floor 15, Suite 1503 Tel Aviv 64239 , Israel Email: _ ___, Mobile phone: ____ (b)(6) _.Cb ..,) ..,(6) .., NIH-000618 , -~ NIH-000619 ~!B iotherapy In1ernat1onaI NIH-000620 From: (b)(6) Date: To: Subject: Sat, 14 Mar 2020 19:11:42 -0400 Alex Amonette Re:Thank you for your leadership! Thank you for your note. A.S. Fauci. Sent from my iPhone On Mar 14, 2020 , at 5:43 PM , Alex Amon ette (b)(6) wrote: Dea r Dr . Fauci, Thank you for your leadersh ip and expertise on the coronav irus and for your other great works . You are a true hero . Thank goodness you are here for all of us r ight now. No reply expected . To your continued good health fo r many many years to come! Sincerely, A lexandra Amonette (b)(6) NIH-00062 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 14 Mar 2020 19:22:47 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Use SARSDrugs From: (b)(6) Se nt : Saturd ay, March 14, 2020 3:22 PM To: Fauci, Ant hony {NIH/NIAID) [E] Subject: Use SARS Drugs -----~~ ------- (b)(6)> Dr. Fauci; In germany they found the drug camostat mesilate they used on SARS in 2003 kills the coronavirus in a petri dish. why wouldn't you give it a try? Will drug companies lose too much monies? Makes sense to use an already approved drug with little side effects. God is watching !!!!!!!!!!!!! NIH-000622 From: Folkers, Greg (NIH/NIAID) [E] on behalf of Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 17:49:09 +0000 Halula, Madelon (NIH/NIAID) [E];Fauci, Anthony (NIH/NIAID) [E] RE: Thank you - It 's worth it Date: To: Subject: Thank you! From: Halula, Madelon (NIH/NIAID) [E] Date: Monday, March 9, 2020 10:10 AM To: Fauci, Anthony (NIH/NIAID) [E] --------- = ------~~ (b)( > ________.. (b)( 6h Subject: Thank you - It's worth it Dear Dr . Fauci, Than k you for being willing to step up publ icly and have your life over taken by the coronavi rus. This can't be easy and is likely to be harder in the coming weeks and months. Know that we appreciate it and that I am willing to do whatever needs doing to help. Sincerely, Madelon Halula Madelon Halula, PhD Initiative Coordinator Email : (I?)(© Tel (b)(6) FAX: 240-627-3466 DHHS N IH NIA ID DAIDS Scient ific Program s & Ope rations Branch MSC 9831 (rm 8C48} 5601 Fishers Lane Rockville , MD 20852-9831 .~ The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases shafl not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . ~ NIH-000623 (b)(6) From: Date: To: Subject: Sat, 14 Mar 2020 13:15:38 -0400 Mike Betts Re: Coronavirus response Thank you for your note. A.S. Fauci Sent from my iPhone On Mar 14, 2020 , at 12 : 19 PM, Mike Bett s ------- (b)(6)>w rote: I wanted to convey an idea I had with regard to the coronavirus. It seems to me that trying to contain the virus as we are doing at present will be futile. Since the virus can be present for many days without a person having any symptoms, you would literally need to test everyone at the same time to determine who has it--an impossible task . I have a different thought. We know that the virus is especially dangerous for the old and/or immunosuppressed. IMO we should be focusing all of our efforts on keeping that group from becoming infected. To do so that group should be encouraged to self-isolate, to limit their social interactions and other groups should be instructed to avoid them. Sort of a reverse-quarantine idea. All testing would be done within those groups and all groups would also be encouraged to continue with the hygien ic suggestions they've already received . The problem right now is that the media has created a panic. Last night my wife and I went to the local Whole Foods and many of the shelves were empty and healthy younger people were wearing masks . The message is not getting out that the virus is almost solely dangerous to the elderly and immunosuppressed. [Why aren't the demograph ics being released? That in itself could calm many people.] With my suggestion, exposures to them would be diminished, significantly reducing the number of deat hs, as well as NIH-000624 the potential impact on hospitals. Any person outside of that group that was severely affected could be identified and treated. Quarantining otherwise healthy people outside of those groups who finally demonstrate symptoms--like the NBA players--is ridiculous. They are likely to get the sniffles and have also already spread the virus. As long as they're not spread ing it to the endangered group we should not worry about it. In sum, we need to isolate the vulnerable and realize that the mortality rate for people outside of that group is likely lower than the flu. Of course , while this occurs we are working on finding treatments and vaccines. But sending home workers who have next to no likelihood of being significantly impacted by this virus is ridicu lous. The virus hits hardest the old and infirm , two groups that are most likely NOT to even be in the workforce! To me, this solution is a lot simpler than what is being tried right now and is much more likely of success. To everyone besides the endangered group this virus is literally less dangerous than the flu. There is no reason that anyone outside of the endangered group should have any concern at all and we need to make that clear. Please let me know what you think. Sincerely , Michael Betts (b)( NIH-000625 From: Date: (b)(6) To: Subject: Sat, 14 Mar 2020 13:14 :36 -0400 Sharon Ganderson Re: Subject. Virus recommendat ions Thank yo u for your note. A.S . Fauc i Sent from my iPhone On Mar 14, 2020, at 12:42 PM , Sharo n Ganderson Cb)~ wrote: Dear Dr. Fauci: Thank you for your incre dible dedicatio n &expert ise in dealing w ith the coronaviru s situation. My conce rn is that when the President &the virus team and others are seen together they stand close together &shake bands. This has been ill advised by all the medical expe rts, includin g yo u. I m ho ping you and the other expe rts will strong ly advise changes in this behav ior in accordance with current recommenda tions. We need them to se t a good exam ple for all. Many thanks for your help - its greatly app reciated. Sharon Fink (b)(6) NIH-000626 From: Date: To: Subject: (b)(6) Sat, 14 Mar 2020 13:12:23 -0400 Adrienne Delucca Re:THANK YOU Thank you for your note. A.S. Fauci Sent from my iPhone ----------- > On Mar 14, 2020 , at l :04 PM, Adrienne Delucca (b) (6) > wrote: > > > Dear Dr. Fauci: > > My name is Adrienne Delucca and I live in Connecticut. I am a Labor Attorney and repre sent almost 40,000 public school teachers. You may not read this until months from now a~I know you are working tirelessly on the Coronavirus Task Force. I just felt the need to send you a quick note to thank you. Your expertise and presence during inter views and Whit e House briefing has offered me so much comfort at such an anxiety ridden time. l have heard from so many friends and family members who feel the same way about you. Without your involvement we wouJd be lost as yours is the most credible vo ice that we have come to rely on. Thank you for all you are doing for our country. We are all so lucky to have you. I pray that you and your family stay healthy. > > Sincerely, > Adrienne Delucca NIH-000627 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:10:59 +0000 Celia Lewis RE:No BS Celia and Jim: Thank you for your kind note. Berst, Tony From: Celia Lewis (b)(6)> sent: Saturday, March 14, 2020 6:44 AM To: Fauci, Anthony (NIH/NIAID) [E)------= Subject: No BS (b)""'(6J => Dear Dr. Fauci: My husband and I are both ----- (b) (6) so we've followed a lot of TV news regarding COVID-19. We want to express our appreciation for your "no BS" presentation of the realities of the disease spread and what we, as a country, can expect . We hear the polit icians and the news anchors, but we find our comfort in the unwav ering truth you deliver through the lens of your decades of experience and experti se. And we thank you, more than you know. Highest regards, Celia and Jim Lewis NIH-000628 From: Date: To: Subject: Fauci,Anthony (NIH/NIP.ID)[E] Sat, 14 Mar 2020 13:09:28 +GOOO Diane Gaarv RE:Thank you Than.ks, Diane. I will try your suggestions. ----- Original Message ----- From: Diane Gaary ..----- .-,;-,-= (b) (6) Date: Saturday , March 14, 2020 7:45 AM To: Fauci , Anthony (NIH/NIAID) [E]..._______ ------~~ = (b _)_(6) ... Subject: Thank you Dear Dr Fauci, Thank you. Your efforts to infonn and help all of us during the Covid-19 situation are greatly appreciated. You are in our prayers. Sincerely, Diane Gaary PS. I am a speaking voice teacher. If your voice is tired from the constant talking , here are 2 easy suggestions: 1) a closed mouthed yawn (as one might do in a boring class) is a quick stretch and tension reliever for the entire vocal mechanism 2) 10-20minutes of constructive rest (on your back with knees bent and head on a book to keep it in line with your spine) will put your spine into a passive traction and give your back and neck muscles a chance to rest and release l know you don' t have much time for this sort of thing, but decreasing your physical stress will help your voice tremendously and help you work even more efficiently. Once again, Thank you for your knowledge commitment , and integrity. NIH-000629 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 13:05:46 +0000 Deb Webster RE:Thank you Deborah: Thank you for your kind note. Best, Tony -----Original Message- ---- From: Deb Webster.-------~ (b ~)~(= 6J Date: Saturday, March 14, 2020 9:04 A"'M ;..;;..... ____ To: Fauci, Anthony (NTH/NIAID) [E]______ Subject: Thank you ~~ _> Cb _<_. Dr. Fauci, J have been so very heartened and impressed with your forthcoming and rational communications and actions around the COVID-19 crisis. This includes your insistence on speaking trnth to power and taking more aggressive steps in thls combat. Don't relent, and keep up the great work. We all need you. ] wish you well. Deborah Webster (b)(6) NIH-000630 From: Fauci, Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 12:58:29 +0000 William Templeton RE:Thank you Date: To: Subject: William. Thank you for your kind note. Best, Tony From: William Temple t on __________ Cb _) _ (6)> Date: Saturday, March 14, 2020 8:33 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: Thank you (b)(6);, -------- _____ ......as an (b)(6) Infectious Diseases physician in southern Indiana and Louisville. During my career I cared for hundreds of individuals with HIV/AIDS and remember well your tireless efforts in this regard. Even in the midst of the cur rent coronavirus pandemic, your know ledge and expertise cont inue to preva il- a model for many . There has never been a more important time for dissemination of facts not blind faith . Again, congratulations ! William C. Templeton, MD NIH-000631 NIH-000638 (bX5) -PCP. NIH-000639 From: Date: To: Fauci,Anthony (NIH/NIAID) [E) Sat, 14 Mar 2020 00:32:38 +0000 Bill Canavan Subject: RE: REGISv FORDHAM (b)(6) Billy: Thank you so much for you note. You brought back a flash of happy memory that was wedged in the bottom of my brain. What a game that was! Billy Canavan and Donnie Walsh versus Tony Fauci and Artie Guar ino. You guys were clear ly better than we were; yet we won which proved to me then that anything is possible. Thanks again for bringing back such amazing memories. I hope that yo u are well and I wish you all the best. Warm regards, Tony From: Bill Canavan Date: Friday, March 13, 2020 8:23 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= Subject: REGISv FORDHAM .... 1958 ... (b)(6)> (b-:)(=6) TONY ... BEAT CORONAVIRUS THE WAY YOU AND ARTIE BEAT DONNIE AND ME BILLY CANAVAN ... NIH-000640 --- (b)(6) REGARDS... From: Date: To: Subject: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 17:54 :56 +0000 Alecia Siuta;Fauci, Anthony (NIH/NIAID) [El RE:Thank you and how can I help? From the wife of a hospitalis t Dr. Fauci asked me to thank you for your note. Best, Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institute s of Heal th 31 Center Driv e, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) sha ll not accep t liabi lity for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. -----Original Message----from : Alecia Siuta :.:-------(b ~)-(6) ~ Date: Friday, Ma rch 13, 2020 1:53 PM To: Fauci , Anthony (NTH/NTAID)[El (b)(6) > Subject: Tharlk you and how can I help? From the wife of a hosp italist -----~~= Dr. Fauc i, Thank you so much for being the honest, clear minded medical leader that our country needs right now. You are doing a superb job handling this difficult situation. My ______ (b)(6) a hospitalis t in State College, PA is on the front lines of this impending crisis in our community (he is (b) (6)ra;'1d also works clinically for both intemal medicine and pediatrics). Tappreciate the clear and easy to understand campaign to the genera l public to "flatten the curve" and slow the inev itable sp read so that we don't overwhelm the medical community's capac ity to care for the seriously ill. I sugge st that to add to this campaign (espec ially given the serious lack of testing; current ly he is waiting 4-7 days for test results for hospita lized sus pected covid-19 patients ) that you make it clear to the American public that they should NOT go to their docto r/hospital/ urgent care and instead stay at home, isolate themselves, and make a phon e call to their doctor 's office or some sort of dept of health hotline. If everyone with mi ld/moderate symptoms (and their imme diate contacts) are bringing the virus into medical fac ilities, it greatly increases exposure and outs healthcare workers (and their families and communities) at unnecessary risk. We need to convey to the Ame rican public the importance of keeping our healthcare workers from falling ill (and into quarantine) so that they can treat those that absolute ly need to be hospitalized. There also should be a mandated no visitor policy for suspected/confirmed patients al every point of care. NIH-00064 1 I am interested in helping in any way lam able. Please let me know what I can do to increase awareness and spread the vital messages you are trying to convey. Thank you for your service and sacrifice for the greater good of the American people, Sincerely, Alecia Fay Siuta (b)(6) Sent from my iPhone NIH-000642 From: Date: Conrad, Patricia (NIH/NIAID) [E) on behalf of Fauci, Anthony (NIH/NIA ID) [E) Fri, 13 Mar 2020 15:52 :12 +0000 Lynda Hayashi;Fauci, Anthony (NIH/NIAID) [E] RE: dr ive up covid-19 te sts for Washington State To: Subject: Dr. Fauci wanted me to thank you for your note. Best, Patric ia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax Discla imer: Th e informat ion in this e-mail and any of its attachme nts is confidential and may contain sens itive info rmation. It should not be used by anyone who is not the original intended recipien t. If you have received this e-mail in error please info rm the sender and delete it from your mailbox or any other storage devices . National Institu te of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Lynda Hayashi Date: Thursd ay, March 12, 202010 :17 PM To: Fauci, Anthony (NIH/ NIAID) [E]______ (b)(6) (b ...,)"'~= > Subject: dr ive up covid-19 tests for Washington State If South Korea can make th is happen why can't we? At least here in t he most hardest hit state . Please make t his happen. We're all scared. Lynda C. Hayashi (b)(6) NIH-000643 From: Date: (b)(6) To: Fri, 13 Mar 2020 09:23:12 -0400 NIAID Pub lic Inquir ies Subject: Fwd: Coronavirus quest ion - please read Sent from my iPhone Begin forwarded message: From: Zofia Agee Cb)(6)> Date: March 13, 2020 at 8:02:50 AM EDT To: "Fauci , Anthony (NIH/NIAID) [E]" --------~= Subject: Coronavirus question - please read ---------- CbH6>: Dr. Fauci, I'm not a medical professional. I'm just someone who is paying attention to what is going on. I'm hearing that in many cases people have died because they developed pneumonia due to coronavirus. Since there is no coronavirus vacc ine and won't be for a while can pneumonia be prevented by getting pneumonia vacc ination? To me, that seems like a very logical course . I was actually trying to get that vacc ine but I was turned away because I do not have any medical history showing that I need it and I'm not 65 yet. Could this be some way to lower the death while working on the vaccine? I have sent this to a few other places/peop le but not sure I'm reaching the right people, so I'm hoping it will reach you or someone in your office that will read it:). lfw e can not cure the virus yet, maybe we could get in front of it and prevent it from being deadly ... Just a thought. Zofia Agee Zofia Agee (b)(6) NIH-000644 From: Date: (b)(6) Fri, 13 M ar 2020 09:18:32 -0400 To: NIAID Public Inquir ies Subject: Fwd: thanks very much for your honesty and clear-eyed scientific integ ri ty about coronav irus ! an analysis you m ight want to read or share Sent from my iPhone Begin forwa rded message: From: Jonatha n Fritz CbH6) Dat e: Ma rch 13, 2020 at 8:3 1:51 AM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" CbH6) Subject: thanks ver y much for your hone sty and clear-eyed scientific inte grity about coronavirus! an analysis you might want to read or share --------=-=--= Hello Dr. Fauci, I wo uld like to thank. you for being one of the few honest and tm stworthy scientific v01ces as the world and the US confron t the challenges of coronavirus. I was recently sent this thoughtful statistical analys is and thought you or one of your colleagues might wish to see it. best wishes, yours, Dr. Jonathan Fritz https: //medium .com/@tomaspueyo/coronavirus-act-todayor-people -will-die-f4d3d9cd99ca NIH-000645 From: Date: (b)(6) Fri, 13 Ma r 2020 09:16:52 -0400 Cassett i, Cr istina (NIH/NIAID) [E];Auchincloss, Hugh {NIH/NIAID) [E] Fwd : NK Cells for COVED-19 To: Subject: Pls respond. Sent from my iPhone Begin forwarded message: From: Jeffrey Miller CbH6J Date: March 13, 2020 at 8:53:29 AM EDT -------~~ Cc: "Fauci , Anthony (NIH/NIAID ) [E]" Subject: Re: NK Cells for COVED-19 --------- CbH6J Dr. Fauci , I am working with Ashley Haase and others at Minneso ta to think through the feasib ility and wisdom of this appro ach. Let me know your thoughts if you have the time. You look busy lately ! Jeff On Fri, Mar 13, 2020 at 7:49 AM Jul ian Adams --------- CbTI6>i >wrote: Dear Dr Fauci (Tony), You may remember me from the early 90' s as I was the inventor of nevirapine , the first NNRTi. We met severa l times at NW D and FDA. I have since turned my scie ntific interests to cancer research and discovered and developed Velcade for multip le myelom a. And I have changed career paths again, turning to immuno therapy to treat cancer . I am curr ently the CEO of Gamida Cell with a focus on cellular therap ies. One of our programs is the expansion of allogeneic NK cells. We are collaborating with Dr Jeff Miller at the University of Minnesota and are administering 10-20 billion freshly expanded NK cells in combination with rituximab to pat ients with NHL. The results are stunn ing with 8/ l l patients NIH-000646 achieving CR or very good PR with a single infusion. (see EBMT abstract below). In addition, the safety profile has been remarkably good since two thirds of our pati ents have Karno fsky perform ance <8 0. (NO CRS or Tumor lysis syndrome or neurotoxicity has been observed) (b) (4) I thank you in advance, and look forward to your response, (also copied is Dr Simantov, our Chief Medical Officer) Warmest regards , Julian Adams, PhD EBMT Abstract: (the conference due to have taken place in Madrid is postponed but the abstract is availabl e online) RESULTS OF A PHASE 1 TRIAL OF GDA-201, NICOTINAMIDEEXPANDED ALLOGENEIC NATURAL KILLER CELLS (NAM-NK) IN PATIENTS WITH REFRACTORY NON-HODGKIN LYMPHOMA (NHL) AND MULTIPLE MYELOMA Veronika Bachanova1, David McKenna1, Xianghua Luo1, Todd Defor1, Murali Janakirami, Claudio Brunstein 1, Daniel Weisdorf 1, Erica Warlick1, Rose Wangen1, Fiona He1, Joseph Maakaron1, Zuzan Caycii, Bartosz Grzywacz 1 , Guy Brachya 2, Tony Peled 2 , Jeffrey NIH-000647 Miller 1 1University of Minnesota, Masonic Cancer Center, Minneapolis, MN, United States, 2Gamida Cell, Jerusalem, Israel Background: NK cells have the capacity to kill tumor targets and potential in cancer therapy. Limitations include specificity, persistence after infusion and how to maxim ize NK cell activity in vivo. We report results of a Phase 1 clinical trial of GDA-201, a cellular product composed of Natural killer (NK) cells from healthy donors expanded ex-vivo with nicotinamide (NAM) and IL-15, a unique ex vivo activation strategy to induce persistence. Prior in vitro studies and pre-clinical models demonstrated that NAM-exposed NK cells exhibit augmented resistance against exhaustion and improved killing function, proliferation, and organ trafficking. We report safety and preliminary efficacy from a phase I trial of GDA-201 in patients (pts) with relapsed or refractory (R/R) NHL or MM. Methods: Following donor apheresis, CD3-depleted mononuclear cells were cultured for 14-16 days with NAM (5mM) and IL-15 (20ng/m l), resulting in a 40-fold increase in NK cells and increased expression of CD62L from 2.9% to 21%. GDA-201 contained ~98% NK cells, and CD3 content was maintained at <0.5% (<5x10s/kg/dose). Pts with R/R B-cell NHL or MM received cyclophosphamide (400mg/m 2 IV x 3d) and fludarabine (30 mg/m 2 /d IV x 3d), followed by two doses of GDA-201 (Days 0 and 2) and low-dose IL-2 (6 million units sc). Pts with NHL or MM received rituximab (375 mg/m or elotuzumab (10 mg/kg), respectively, x 3 weekly infusions to enhance NK cell targeting through antibodydependent cellular cytotoxicity (ADCC). Results: 25 pts were enrolled:11 with NHL (5 follicular, 5 diffuse large cell lymphoma, 1 mantle cell lymp homa) and 14 with MM, in 3 cohorts of escalating GDA-201 dose; 14 pts received the maximum target dose (median 1.7 x 1Qscells/ kg, range 1.6-2.0 x 1Oscells/kg). There were no dose lim iting toxicities. The most common grade 3/4 adverse events were neutropenia and thrombocytopenia, febrile neutropenia (n=2), increased creatinine, hyponatremia, pulmonary edema; all events were transient. There were no neurotoxic events, confirmed CRS,GVHD or marrow aplasia. One patient died of E-coli sepsis. r4mong 11 NHL pts, there were 7 CR and 1 PR with an overall response rate of 72%. Median duration of response is 11 months (CR patients) and 3 months (PR pat ients). In MM patients, 1 patient with extramedullary disease had CR and 4 had SD with median duration 2.5 months. In our previous study using overnight activated NK cells, persistence 7 days after adoptive transfer was limited. Using GDA-201, flow cytometry confirmed 2 ) NIH-000648 the persistence of donor NAM-NK in peripheral blood up to day 7-10 (day 7 range 2-55% donor NK cells; Figure 1), as well as enhanced in vivo proliferation (median Ki67 99%). In addition, the enhanced expression of the homing receptor CD62L correlated with trafficking to bone marrow and lymp h nodes in vivo as confirmed by flow cytometry of biopsied tissues at day 4. Conclusions: Cellular therapy using GDA-201 with mono clona l antibodies was safe, and demonstrated early evidence of clinical activity in heavily pre-treated pts with advanced NHL and MM. Laboratory studies show that the GDA-201 product shows better persistence. Larger phase II studies are warranted. Clinical Trial Registry: clinicaltr ials.gov NCT03019666 Disclosure: Funding for the trial is provided by Gamida Cell. BMS is providing drug only support. Veronika Bachanova: Research Funding Gamida Cell, Advisory Board: Gamida Cell Julian Adams , Ph.D. Chief Executive Officer Gamida Cell 673 Boylston St 4th Fl Boston, MA 02116 (b)(6) Heather DiVeccbia Chief orStaff Gamkla Cell Ud. Cell Therapy Technologies 673 Boyls ton Street, 4 th Floor Boston . MA 02 116 Direct: (b)(6) NIH-000649 (b)(6) www.gamida-celJ.com gamida~ell s. Jeffrey Profes sor Mille r , M.D. of Medicine Deputy Director , 11asonic Cancer Center Division of Hematol ogy , Oncology and Transplantation, Roger L . and Lynn C. Headrick Famlly Univers it y of Minnesota Cha i r in Cancer Therapeuti cs Regular Mail : Divisio n of Hematology , Oncology , and Transplantation 420 Delaware St . SE, Mayo Mail Code 806 Minneapolis , MN 55455 Federal Express or courier University of Minnesota 425 E. Riv er Road Minneapolis delivery: Cancer Center , Room 654A , MN 55455 CONFIDENTCALITY NOTICE:Electronic parties . '!'he University of messages Min nesota can canoe not misctjrectect a nd does not or Lntercep tect oy unint enctect g u.;,rantee c he confidentiality messages sent over the I n te rnet . Messages sent to or received from work e -mail accounts also may be monitored or vie wed by your employer . I f you have rece i ved this communication in error , plea se notify the sender imme diately a nd delete NIH-000650 the information . of (b)(6) From: Date: To: Subject: Fri, 13 Mar 2020 09:10 :05 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: UV light for COVID-19 prevention Sent from my iPhone Begin forwarded message: From: David Levi Date: March 13, 2020 at 9:06: 16 AM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: UV light for COVID-19 prevention (b)(6) > ------~~ (bH6J · Thank you for all your hard work trying to deal with this horrible pandemic. P lease cons ider ways to get UV light cleaning devices through out the U.S. that they are currently using in Wuhan, China to attempt to contain this virus. Closed schools and sports venues can be cleaned with UV light while workers wear PPE and sunglasses to protect themselves. This pandemic could be seen as an opportunity to help prevent the spread of other contagious diseases by impl ementing rational public policy such as UV cleaning when schools and sporting events have concluded . It may also help "flatten the curve" and hopefully rebuild consumer confidence so we can resume activ ities such as travel and commerce that is vital for the healthy of not on ly our economy but our citizens . Thank you again for your work and your time. Sincerely, Dr. David Levi NIH-000651 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 09:09:39 -0400 NIAID Public Inquiries Fwd: Metr ics Sent from my iPhone Begin forwarded message: From: Steve Fisher CbH6) Date: March 13, 2020 at 9:06:43 AM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Metrics CbH6Jr Thanks for your hard work on Coronavirus. What we desperately need are specific metrics (available daily to everyone) on the disease. We also need to know how to evaluate them. When will we know if it is getting better? It is really as bad as the med ia would have us believe? Please set some goals and objectives on the metrics so we know where we are and know when we have won or lost . Yesterday Rush Limbaugh compared this to data on the Swine Flu in 2009 (60 million cases, 275,000 hospitalizations, 12,500 deaths from your website) and suddenly the Corona virus doesn't sound very bad at all. Yet we have shut down the world economy and done irreparable harm to many lives. Can you explain this? Frankly no one even remembers the Swine Flu epidemic on ly 10 years ago. SieJ>Re JJ.£.i sb_e ._._ __ ,.._,,,_, (b)(6) NIH-000652 From: Date: (b)(6) To: Subject: Fri, 13 Mar 2020 07:22:03 -0400 Morris Flaum Re: Thank you Thank s, Morris. I appreciate your note On Mar 13, 2020, at 12:37 AM, Morris Flaum --------- (b)(6) wrote: Dear Ton y, I had the good fortune of working with you and Ha rvey Gralnick when I was a Clinical Associate at the NIH from 1977-1979. I am writing to expre ss my deep app re ciation for speaking truth to power and being one of the few honest voices in the governme nt at this time of crisis. Your confidence and approach to articulating the issue and ramifications have provided critical information to the American population. Although COVID-19 is a un ique event, we would have been much better prepared had you been leading the effort,;; in dealing with this outbreak. Th e US owes you a great deal of gratitude. Morris Flaum Morris A Flaum, MD , MBA Flaum Consultants , LLC Consultant to the Healthcare Industry NIH-000653 From: Date: (b)(6) Fri, 13 Ma r 2020 07:18:58 -0400 Lerner, Andrea (NIH/NIAID) [E) Fwd: Trial by fire? To: Subject: Please handle Begin forwa rded message: From: Aaro n Harber Cb)(6) Date: March 13, 2020 at 6:52:52 AM EDT --------~~ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Trial by fire? ---------- CbH6) Dear Tony, You're doing a grea t job und er terrible circums ta nces so I hop e you hang in th ere . I'm sure th e President is driving you nuts at t im es. T know you 're probab ly far too busy to do yet an ot her program with me (HarberTV.com / Fauci ) but, if you can send me a coupl e of quick answers this morning, that wo u ld be great. l. Do you think it' s realistic we could have an effective vacci ne for the COVID-19 virus by this Fall? My guess is it will be more like the Fall of 2021 but tell me if I might be wrong. 2. Given that we've known abou t the probability of a pan demic, why are we so poorl y prepared to address it (e.g., mas ks, test ing k its, medical staffing et cetera)? I rea lize most of the needs rarely occur an d when they do, th ere are extraordinary spikes in demand for cer tain products and expertise but one wou ld think the re are ways to address this far bett er than we have. 3. Is there anything people should know that is not being emphasized? Thanks for any resp onse you can sen d, even if it's a few words. And keep up the good work . You are greatly appreciate d . Best wishes, Aaron Aaron@HarberTV.com NIH-000654 P: (b)(6)(+voicemail) C: (b)(6) (+texts) Ha rberTV .com /I nfo + Har berTV.com /Awa rd NIH-000655 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 13 Mar 2020 01:26 :08 +0000 Marston, Hilary (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El RE:Moderna trial To: Cc: Subjec t: Need less to say, ___________________ Cb _H_5. -----Origi11alMessage----From: Marston, Hilary (Nll-1/NIAID) [El Date: Thur sday, March 12, 2020 8:23 PM To: Grigsby , Garr ett (HHS/OS/OGA) Cc: Stecker , Judy (OS/ TOS) (b)(6) -------~ Mango, Paul (HHS/IOS) Kyle (HHS/0S /OGA) ----- (b)( (b)(6) = (b)(6) > (b)(6) >; Pauc i, Anthony (NIH/NIA ID) [E] (b)( ·; Harrison, Brian (HHS/TOS) ...______ (b)(6) ; ....., Cb _H....i ; Zebley, >; Richardson, Juliana (HHS/0S /OGA) Su~ject: Re: Modema trial Correct - as of right now (b) (5) Will let you know ifthere is an unforeseen delay. On Mar 12, 2020, at 7: 19 PM, Grigsby, Ga rrett (HHS/OS/OGA) > > Hilary, --------- (b) ( wrote: )(5) > > Please let us know soonest. > > Many thanks! > > > > > Sent from my iPhone NIH-00066 1 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 10:28:35 +0000 (b)(6) (OS/IOS);Giroir, Brett (HHS/OASH) Harrison, Brian (HHS/10S);Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) RE: High Risk from CDCWebs ite Just checked the CDCguidance, which I had not had the t ime to read before. The secret ary w as CbH5) correct Here it is: (b)(S) From: (b)(6) (OS/105) (b)( > Date: Wednesday, March 11, 2020 5:28 AM To: Giroir, Brett (HHS/OASH)'======='--=" Cc: Harrison, Brian (HHS/105) (b)( >; Stecker, Judy (05/105) (b)( ; Fauci, Anthony (NIH/NIAID) [E] (b)(6J>; Redfield, Robert R. (CDC/OD) (b)(6) Subject: Re: High Riskfrom CDCWebsite "'.'--.-'.":=====-=~ Thanks Brett. Tony and Bob, (b) (5) (b) (5) On Mar 10, 2020, at 6:59 PM, Giroir, Brett (HHS/OASH)_______ Brett P. Giroir, MD ADM, us Public Health Service NIH-000690 Cb _)_C6) _ wrote: Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) NIH-000691 From: Date: Fauci, Anthony (NIH/NIAID) [E) Wed, 11 Mar 2020 01:59:54 +0000 To: Stecker, Judy (OS/10S);Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E);McGowan, Robert (Kyle) (CDC/0D/OCS);Lepore, Loretta (CDC/0D/OCS);Murphy, Ryan (OS/ASPA) Subject: RE: URGENT(b)(5) -------,;- ~ I amok with this -------------~ -------- From: Stecker , Judy {OS/10S) Date: Tuesday, Ma rch 10, 2020 9 :54 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > (b)( ' (b)( =; Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)( ; McGowan, Robert {Kyle) (CDC/0D/OCS) . ---:----:-~===~~ (b)(6) >; Lepore, Loretta (CDC/0D/OCS) (b)( ; Mu rphy, Ryan (OS/ASPA) (b)( Subject: URGENT-.__ > _____ (b)__. (5) I understand you both know what this is regarding . Are you good with this? (b)(5) Sent from my iPhone NIH-000703 From: Date: (b)(6) Sun, 8 Mar 2020 09:02 :09 -0400 To: Bright, Rick (OS/ ASPR/BARDA) Lane, Cliff (NIH/NIAID) [El Cc: Subject: Fwd: IL6 R Rick; See below. Tony Begin forwnrded message: From: "Lane, Cliff (N IH/NIAID) [E]" Date: March 7, 2020 at 11:33:28 PM EST To: "Fauci, Anthony (N IH/NJA ID ) [E]" ______ Subject: Re: IL6 R (b)(6)i ------~~ (b_><_ > (b) (5) lt poss16le, 1t woulo 6e of mterest to receive a copy or1'11eChmese treatment guidelines you reference. Thanks, On Mar 7 , 2020 , at 10: 13 PM , Fauci , Anthony (NIH/NIA ID) [E] (b)(6) wrote: Please advise. -------- From: Bright, Rick (OS/ASPR/BARDA) Date: Saturday, March 7, 2020 3:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (OS/ASPR/I0) (b)(6) -------=-:--= (b)(6),; Kadlec, Robert (b)( Cc: Walke r, Robert (OS/ A _ s_P_R.:.. /B_A_R _D_A.:. ) ===~~-~-- (b_H_6); Disbrow, (b)(6); Johnson, Robert Gary (05/ASPR/BARDA) (OS/ASPR/BARDA) [E] (b)( _______ ; Marston, Hilary (NIH/NIAID) (b)(6); Shuy, Bryan (OS/ASPR/10) (b)(6); _, Redd, John (OS/ASPR/SPPR) Subject: Fwd: ll6 R NIH-000828 -------- (b)(6) Dr Fauci, I know that Dr Kadlec has mentioned the news we heard from genentech about the evaluation of monoclonal antibodies to IL-6 and IL-6R in severely ill COVID-19 patients in China. Additional information became available yesterday and we learned that China updated Their clinical guidelines to include anti-I LG. (b) (4) (b) (5) I welcome your thoughts and would also make our team available fo r a quick call if you prefer. Many thanks. I know you are very busy. Rick Begin forwarded message: (b) (4) NIH-000829 (b) (4) NIH-000830 (b) (4) NIH-00083 1 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 15:35:47 -0500 Lane, Cliff (NIH/NIAID) [E] Fwd: IL6 R Sent from my iPhone Begin forwarded messag e: (b)(6) From: "Bright, Rick (OS/ ASPR/BARDA)" Date: March 7, 2020 at 3: 18:02 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( ·, "Kadlec, Robert (OS/ASPR/10)" (b)(6)> Cc: "Walker, Robert (OS/ASPR/BARDA)" (b)(6) , "Disbrow, Gary (OS/ASPR/BARDA)" (bH >, "Johnson, Robert (OS /ASPR /BARDA)' (b)( >, "Marston, Hilary (NIH/NIAID) ,------[E]" (b)(6)"Shuy, Bry an (OS/ASPR/IO) " (b)( >, "Redd , John (OS/ASPR/SPPR) " (b)(6) Subject: Fwd: IL6 R --------------~~ ---------=-:-:= _,------- -------- ---- ---------=-=-= Dr Fauci , I know that Dr Kad lec has mentioned the news we heard from genentech abou t the evaluation of monoclonal antibodies to IL-6 and IL- 6R in seve rely ill COVID-19 patient s in China . Additional information became available yesterday and we learned that China updated Their clinical guideline s to include anti-IL6. (b) (4) (b) (5) Many thank s. I know you are very busy. Rick Begin forwarded mes sage: NIH-000859 (b) (4) NIH-000860 (b) (4) NIH-00086 1 From: Date: To: Subject: Attac hments : Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 02:58:28 +0000 Redfield, Robert R. (CDC/OD);Birx, Deborah L. EOP/NSC RE: County specific guidance Seattle_Community_Mitigtion_3_10 as version final with minor Fauci ed its ..docx, Santa Clara_Community_Mitigtion_3_10 as (002) - with Fauci minor edits.docx Bob : They look pretty good . I have made a few minor changes that are tracked in the attached documents. Best regards, Tony From: Redfield, Robert R. (CDC/OD)____ Date: Tuesday, March 10, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E)-----(b)(6) Subject: Fwd: County specific guidance _> Cb _<_ > (b ~)-(6) ~ >; Birx, Debora h L. EOP/NSC Draft I am reviewing now but wanted you both now so not delay Get Out look for iOS From: Schuchat, Anne MD (CDC/OD) CbH6J> Date: Tuesday, March 10, 2020 5:58:15 PM To: Redfield, Robert R. (CDC/OD) (b)(6)> Cc: Cohn, Amanda (CDC/DDID/NCIRD/OD) (b)(6J>;Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6J>;Redd, Stephen {CDC/DDPHSIS/OD) CbH6J>; Messonnier, Nancy ----- (CDC/DDID/NCIRD/OD) (b)( >; Schuchat, Anne MD (CDC/OD) Robert (Kyle) (CDC/0D/OCS) (b)(6);Berger, Sherri (CDC/OC00/0D) Warne r, Agnes (CDC/0D/OCS) CbH6J> Subject: FW: County specific guidance Or Redfield: Attached please find (b)(6J>;McGowan, (b)(6J>; (b)(5 t (b)(5) Note that if you are trying to send to Debbi Birx she mentioned that things going to her CDCemail will not reach her so you may want to include Olivia Troye to make sure to meet your deadline. NIH-000702 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Tue, 10 Mar 2020 17:54:45 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE:Great talk Jon: Thank you for your kind note. It is much appreciated. I hope that you are well. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Date: Tuesday, March 10, 2020 1:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J> Subject: Great talk ------ CbH > -------= ~ Tony: Superb presentation on COVID- 19 today! ----------• Excellent work with the media, Congress, and scientific community--you have made a great difference for the nation and world in a complex time . Best, Jona NIH-0007 10 From: Date: (b)(6) Fri, 13 Mar 2020 06:26 :43 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Urgent info rmation about a Corona Virus Management Device Attachments: M edixair Micro virus report. pdf, ATT000Ol.htm, M edixai r White Paper - 2016 Jan.pdf 1.pdf, ATT00002.htm Please handl e Begin forwarded message: From: Ani John (b) (6)> Date: M arch 13, 2020 at 3 :13:38 AM E DT ------~~ To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6J Subject: Urgent information about a Corona Virus Management Device Dear Dr. Fauci Given the gravity of the corona pandemic, my brother and I are reaching out to make you aware of product that we think could help mitigate the spread of the virus and protect health care workers as well as the public . We have already tried the usual channels to contact the Wh ite House and the emergency authorization use division at the FDA but also wanted to bring this to your attention also. Medixair™ , an ultraviolet (UVc) air sterilizer with proven , well established unique patented germicidal technology to effectively and safely eradica te viruses and bacteria up to 99.9%. It is capable of delivering a log6 reduction in microbial concentration , by penetrating the nucleus of microorganisms, disrupting their DNA thus destroying the ability of the organism to reproduce ; effectively rendering it harmless . Medixair™ is a portable unit and can easily be installed in a variety of settings including hospitals , emergency rooms , waiting rooms , dentist offices , cruise ships and airport lounges. In both clinical trials and under invitro testing conditions (see attached white paper) , Medixair™ has been demonstra ted to be highly effective in protecting patients and health care workers from pathogens (e.g. MRSA, Clostrid ium Difficile) and also by preventing cross infection . Specifically , Medixair™ was tested and found effective for a strain of Coronavirus known as FCoV and thus COVID-19 would have the same susceptibility to eradication with UVc within a relatively short period of time (attached). NIH-000656 Medixair™ has been on the market since 2005 and is fully CE marked to EN standards. Currently it has been safely and effectively used in acute hospitals , dental surgeries , in UK, Malaysia, India, Israel, and Southern Africa . Please let us know how we can help make these units available for use in the US during this critical period of time. Kind regards, Ani John , BSN, MPH, PhD San Ramon, California Mathew Kaye, Manufacturer of Medixair™ Dudley , United Kingdom NIH-000657 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:19:54 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Question from Jefferson Health NE Philadelphia Please respond or refer. From: Robert Danoff (b)(6) Date: Thursday, March 12, 2020 11:02 PM To: Fauci,Anthony (NIH/NIAID) [E] ------= (b-c)(c-= 6) Subject: Question from Jefferson Health NE Philadelphia Hi Dr. Fauci, Hope all is wel l. Dr. Fauci, we will be setting up COVID-19 testing facilities and I wanted to ask your opinion regarding the following: Is it ok to expand our testing beyond the current strict testing criteria to includ e those with lesser symptoms or potential exposure whom we want to rule out Covid-19? We are concerned that while we isolate those with more severe symptoms who currently qualify for testing, the majority with lesser symptoms would be ambulatory and potentially spreading the illness to others. Plus, it is hard to get someone to isolate for 14 days without prov iding a diagnosis. Just as we can test those we suspect fo r Inf luenza A, Influenza Band RSV,it would be helpful to be able to test those we suspect with Covid-19, including healthcare workers with no symptoms but with possible exposure. Thank you for your time and your leadership for our nation's healthcare. Be well. Rob Rob Danoff DO, MS, FACOFP,FAAFP Program Director, Family Medicine Residency Program Director , Combined Family Medicine /Emergency Medicine Residency NIH-000658 Jefferson Health - No1theast Clinica l Pro fessor of Famil y and Coilllmmity Medicine Sidney Kimm el Medi cal College of Thomas Jefferson University (b)(6) Jefferson Philadelphia University + Thoma s Jeff e~o n Unlversity HOMEOf 5IDIUYKIMMUMB>ICAI. CDlLEGf The info r matio n contained in this tr ansmiss ion contains privilege d and confidential information. It is intended only for the use of the person named above. I[ you are not the intended recipient. you are hereby notified that any review, dissem ination . distribution or dup lication of this communication is strict ly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. CAUTION: Intended recip ients should NOT use email communication for emergent or urgent hea lth care matte r s. NIH-000659 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 13 Mar 2020 03:18:51 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Varicella vaccine -COVI0-19 connection Please respond. From: Rose Marie Codling Date: Thursday, March 12, 202011:16 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Varicella vaccine-COVID-19 connection ------- .----..-. = (b)(6) Dr. Fauci, Is it possible that the varicella vaccine could be playing a role in why children are not presenting with the COVID-19 virus? If the vaccine became common around 1995, we wo uld be seeing little to no infection of children and young adults up to about 25 years old, which seems to be the case. Could something in the varicella vaccine have provided immunity to COVID-19? Just an idea from a concerned citizen ... Thank you for your remarkab le leadersh ip during this crisis. Sincerely, Rose Mar ie Codling Rose Marie Codling, Ph.D. Educational Consultant NIH-000660 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 13 Mar 2020 01:23:58 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [El Erbelding, Emily (NIH/NIAID) [El RE:ASM Recommendat ions for speeding up COVID-19 testing (b) (5) I would ------- From: Collins, Francis (NIH/OD) [E] (b)(6)> ------~= _______ Se nt: Thursday, March 12, 2020 8:22 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( _, ; Tabak, Lawrence (NIH/OD) [El (b)(6)> --------- (b) ( > Cc: Erbelding, Emily (NIH/NIA ID) [E) Subject: FW: ASM Recommendations for speeding up COVID-19 testing Hi Tony and Lar ry, (b) (5) (b) (5) Bit of a sto ry he re Thoughts would be most welcome. Franc is From: Collins, Francis (NIH/OD) (E] Se nt : Thursday , March 12, 2020 8:07 PM To: Bertuzzi, Stefano (b) (6b; (b) (6) Cc: Erbelding, Emily (NIH/NIA ID) [E] (b)(6); Stevens-Garcia, Jonathan '"':'"'.":'---;;=:::=====~:;;---"".-:''""' Allen CbH6l;McNult, Peggy (b)(6)> Subject: RE: ASM Recommendations for speeding up COVID-19 testing (b)(6); _...=-:---------- Miller, Melissa (b)( >; Segal, Hi Stefano, Thanks for this rapid turnaround survey and concise recommendations. Adam, I'm g lad to help with conveying this message to FDA- though we should involve ADM Giroir as well. How would you like to proceed? NIH-000662 Francis From: Bertuzzi,Stefano Date: Thursday , March 12, 2020 7:57 PM Cb) (6J> ------------~ -== Miller, Emily (NIH/NIAID) '":"::":-:============::::_--[E] To: Collins, Francis (NIH/OD) [E] Cc: Erbelding, (b)(6) (b)(6) ; '":":':'---::=====~~--:-:~~ Allen (b)(6)> ; Stevens-Garcia , Jonathan (b)(6J>; McNult, Peggy Melissa (b)(6)> ; Segal, (b)(6) Subject: ASM Recommendat ions for speeding up COVID-19 testing Dear Francis and Adam Sorry for the slight delay in gett ing to you the recommendations that ASM collected from clinical lab directors . See attached document. ASM leaders remain availab le for any further discussion that may be helpful to solve the current impasse. Please do not hesitate to contact us, we are here to serve as a resource to you . Sincerely , Stefano St efano Bertu zzi, Ph.D., M.P.H. Chief Executive Officer American Society for Microbiology (ASM) 1752 N St., NW Washington, DC20036-2904 Phon (b)(6) NIH-000663 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 23:20 :57 +0000 Tabak, Lawrence (NIH/OD) [E);Collins, Francis (NIH/OD) [E] RE:Time-sensitive To: Subject: Please be "presumptuous" and go for it. Many thanks. From: Tabak, Lawrence (NIH/OD) [E] Se nt: Thursday, March 12, 2020 7:18 PM To: Collins, Francis (NIH/OD) [E]-------= --------- CbH > Cb "'"" H= ; Fauci, Anthony (NIH/NIA ID) [E] (b)(6)> Subject: FW: Time -sensitive Francis, TonyI am certainly w illing to do this so that neither of you have to, but I did not want to be presumptuous in case either of you preferred a different spokesperson . Please let me know how I should respond to Mary. Thanks Larry From: Mary Woolley Date: Thursday, March 12, 2020 at 10:02 AM To: " Tabak, Lawrence (NIH/OD) [E)" -------- -== (b)(6) Cc: Ellie Dehaney Subject: Time-sensitive Larry, I have a favor to ask. Wou ld you or a designee be willing to join a teleconference next week with our all iance members to discuss NIH's efforts to mitigate the negative impact of COVID-19 on federally funded research? We would need no more than 30 minutes of your time, and can schedule around you. Ideally, though, we could make this happen soon (to state the obvious, everyone is feeling the need for touch points right now , and you are a wonderfully calming one for our university members!) . We could arrange the teleconference fo r as early as this Monday , the 16th: ifthere is a 30-minute window for you or a designee between 1:00 pm and 3:00 pm on that day or within that same block of time Tuesday, the 1ih, we'll commandeer it! Thank you, Larry, for considering this ask. I'm sure it comes amidst many ot hers. NIH-000664 I would love to close by saying something insightful about the indescribable times we were in, but all I can come up with is "indescribable ." My Best, Mary NIH-000665 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:10:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Feds say Florida has 'community spread' of coronavirus. Florida disagrees. Check this out and get back to me. Not sure what he is talking about. From: Robert Tober (b) (6)> Date: Thursday, March 12, 2020 6:44 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=(b""" )(=6) Nancy Lascheid Dolan (b)( ; .. Le - s-:li_ e _L-as-c-:h-ei'."". d-:===::!....-....:... ___ -======= ---------------- (b)(6)>; Gail (b -=)=(6) :;:-- Subject: Fw: Feds say Florida has 'commun ity spread' of coronavirus . Florida disagrees. Dear Dr. Fauci, I am medical director of a charity clinic in Nap les, Florida. A lthough we try to screen pts for cough, fever, sore throat , URI sxs, dyspnea or unusual fatigue, appa rently some patients are asymptomat ic and neg for these 5 hallmarks but still contagious. There is conflict between what our Florida governor states and what CDC states. Do you believe all of our staff should be in goggle s, mask , gown and gloves for AAL PATIENTS that we treat regardless of not meeting one of the 5 screening criteria above. If indeed there is community spread happening, I and many others are sitting ducks. It is not if but when !! Thanks for any guidance you might be able to provide. l am copying to my administrative staff as well. Good luck. This is quite the challenge. Robert Boyd Tober, M.D., F ACEP Medical Director Neighborhood Health Clinic Napl es, Florida 34102 (b)(6)-cell To: Bob Tob er (b)( , Date: Thursday, March 12, 2020, 04:46:08 PM EST Subject: Feds say Flo1ida has 'communit y spread' of corona virus. Florida d isagrees. https://www.tampabay.com/news/health/2020/03/ 11/feds-say-:florida-has-community-spread-of-coronavirus-t1oridadisa grees/ NIH-000666 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Thu, 12 Mar 2020 23:07:14 +0000 Lerner, Andrea (NIH/NIAID) [El FW: Hi Dr Fauci (re : URGENT : epiqar Systems & Coronavirus 2nd tier events) Please handle. From: Jason Ressler (b)( Date: Thursday, March 12, 2020 6:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~~ (b)(6) Subject: Hi Dr Fauci (re: URGENT: epiqar System s & Coronavir us 2nd t ier events) Hi Dr. Fauci, epiqar (https://epigar.com/) is the only system in the world that can help experienced surgeons continue to support teams of less experienced surgeons worldwide, which we're doing with Coronavirus quarantined surgeons in France & Italy now while we expand to other theaters. For Coronavirus care we 've just developed an easy plug in kit for remote hospital surgeries which US hospitals need to be made aware of before they get overwhelmed the way they are in Italy & China. Here 's an article on epiqar from today inThe Hill. Please let me know how we can help your teams. Thanks, Jason Ressler Director, Business Development ENGAUGE/EPIQAR www.en g.us www .epigar .com The world's first low -cost telementoring, surgeon tra ining and instanc Cloud-archiving Platform us 888.615. 7874 EUROPE44 2031399059 NIH-000667 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 12 Mar 2020 23:06:46 +0000 Billet, Cou rtney (NIH/NIAID) [E] FW: Very urgen t Coron avirus Date: To: ---- ------ ,a-s-r:= Subject: (b)(6) NIAID inquiries, please. --------- From: Sushama Talwalkar Se nt : Thursday, March 12, 2020 7:04 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Cc: Conrad , Patricia (NIH/NIA ID) [E] (b)(6)>; Barasch, Kimber ly (NIH/NIAID ) [CJ (b) (6)·> Subject: Very urgent Coronavirus ------ (b)(6) Marc h 12, 2020 Dr . Fauci, (b)(6) Sincerely, Sushama Get Out loo k fo r An dro id NIH-000668 From: Date: (b)(6) To: Subject: Thu, 12 Mar 2020 14:22 :38 -0400 El-Sadr, Wafaa M. Re: Thank you Thanks , Wafaa On Mar 11, 2020, at 8:33 PM, El-Sadr, Wafaa M. Cb)( wrote: ------------ Adding Tony's correct email address. Dear Zunyou , John, Ralph and Tony , Thank you for your superb presentations in the Special COVID-19 Session at the Virtual CROI 2020. As you can imagine, your presentations were very much appreciated by all the audience . There is great thirst for more information at this point in time, which made your presentations particularly timely and impactful. Al I the best, Wafaa Wafaa El-Sadr, MD, MPH, MPA Director, ICAP at Columbia University University Professor of Epidemiology and Medicine Mathilde Krim-amFAR Professor of Global Health Tel: (b)(6) Fax: 212 342 1824 www.icap.columb ia.edu NIH-000669 From: Date: To: Cc: Subje ct: Conrad, Patricia (NIH/NIAID) [Elon behalf of Fauci, Ant hony (NIH/NIAIO) [El Thu, 12 Mar 2020 14:09:11 +0000 O'Donnell, Norah;Fauci, Anthony (NIH/NIAID) [El Verdugo, Adam RE:Thursday night WE are working with Adam. Thank you Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Inst it ute of Allergy and Infectious Diseases Th e National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAi D by one of its representatives. From: O'Donnell, Norah Date: Thursday, March 12, 2020 9:12 AM To: Fauci, Anthony (NIH/NIAID) [E]--------=Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: Thursday night (b"'"' )(=6) ---------- (b)( ; Verdugo, Adam Dear Tony and Patricia, Hoping for tonight from the W hite House or in studio . Adam Verdugo has been in touch and hope we can lock down and confirm ti me. Thank you W!D~□W!D Norah O'Donnell NIH-000670 On Mar 9, 2020, at 8:53 PM, Fauci, Anthony (NIH/NIAID) [E] wrote: -------- (b)(6) External Email Norah: Sorry that I took so long to get back to you. Just got out of the White House a little while ago to get to my office where I am now and it is obviously too late . Please copy my assistant, Patty Conrad, (copied here) in future correspondence. I am so swamped with coronavirus "stuff", I rarely get to e-mail until late at night. Thanks, Tony Anthony S . Fauci , MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6)! FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not th e original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on beha lf of the NIAID by one of its representatives . From: O'Donnell, Norah Date: Monday, March 9, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Verdugo, Adam Subject: Monday night -------c:-~ -------- (b)(6) Dear Dr. Fauci, You are doing an amazing job helping to educate and inform during this crisis. Are you available tonight or any night this week to join us for the Evening News? NIH-00067 1 I am also happy to come to your office . Thank you for your consideration. Norah O'Donnell NIH-000672 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 12 Mar 2020 10:48:06 +0000 Arthur Ammann RE:Art again Art: Good idea. I will ment ion this to CDCduring this AM's daily meeting. Hope that you are well. Best, Tony From: Arthur Ammann Date: Wednesday, March 11, 2020 9:54 PM To: Fauci, Anthony (NIH/NIAID) [E)______ Subject: Art again (b)(6) -------------------=:-:-=,Cb_H_6) Tony. So good to see you now on TV in full charge. Your entire expression has changed almost like when I bumped into you in the Washington Metro after you had gotten off the plane with President Bush. I have an interesting question regarding pneumococcal polysaccharide immunization. One of our staff members phoned. Her father is a physician in France and has many physician acquaintances. She was told that the doctors believe that the older patients who received pneumococcal vaccine have less of a mortality than those who did not get the vaccine. When we did the studies and got the pneumococcal vaccine approved for the elderly in 1976 there was a battle about who should get it and whether was cost-effective. Since then, other studies have documented the benefit, especially in older people and you probably have received it. It is now routine but I know many elderly individuals have not gotten immunized. Historically, many, if not the majority of deaths from influenza in some of the past epidemics was a result of secondary infection with pneumococcus. I'm not hearing anything about urging people to get immunized with pneumococcal vaccine. The message would need to be clear so they don't confuse pneumococcal secondary infection with primary coronavirus infection. It would be a good idea for people to be urged to get the pneumococcal vaccine. If they had not received it. I'm not seeing any recommendations from the CDC or elsewhere regarding this. Please note : this document has been produced by a voice recognition program and may contain errors or words that are out of context. Please let me know if clarification is required . Arthu r J Ammann M.O. NIH-000673 (b)(6) www .Glob alStrat eg ie s.org Ethics in Health http :// ethics inhealth.org / NIH-000674 From: Date: To: Subject: Attachments: Fauci, Anthony (NIH/NIAID) [El Thu, 12 Mar 2020 10:23:36 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: News - Germ/V irus Containment XTI Deck - Key Information OSHA.pdf Please handle . From: ___________________ Date: Thursday, March 12, 2020 6:07 AM To: Fauci, Anthony (NIH/ NIAID) [E]______ Cb _)_(6) (b ""'~""' (6) = > Subject: News - Germ/Virus Containment Importance: High Hi Dr. Fauci, I have been following the news and some interviews with yourself. I was hoping you would be willing to speak with me about our technology? Testing for the positive patients and finding a vaccine are essential, but containment is paramount. We have the only GERM CONTAINMENT TEC HNOLOGY of it's kind. The ongoing Coronavirus and FLU viruses pose a significant threat to public health globally and here in the US. We have the most powerful solution to minimize infection and maximize protection against SARS, EBOLA , FLU, and all types of germs and viruses. With local 3rd party tested efficacy of 100%, no other technology anywhere can yield this result or sustainable 24/7/365 protection . XTI02 is a world exclusive containmen t technology with self-cleaning functions that can help minimize the risk of cross-contamination in hospitals, planes, public transportation, elevators, and public places. XTI02 technology works by forming an invisible protective layer on mostly ALL material surfaces (plastic, steel, glass , fabric, paper, walls, etc ...). It is green, sustainable, and has yielded up to 100% efficacy proven by SGS LABS (US). NIH-000675 I look forward to hearing from you and attached is an information file for you r review. Thank you, Michael Holbert Cleancoati ng LLC 2522 State Rd., BLDG ISPBC Bensalem , PA 19020 http ://www .cleancoa tinq.us Email: Cb)(6) Direct: Cb)(6) Mobile Cb)(6) DISCLAIMER This e-mai l message is intended fo r sole use of the above named recipient(s) . If you are not the intended recipient, you may not review , copy or forward th is e-mail message . If you have received this communication incorrectly , please notify Clean Coating Technologies LLC immediately via e-mail or phone and delete the message accordingly . NIH-000676 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:14:07 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: CORONAVIRUS DATASUPPORTING PROACTIVE EFFORT Begin forwarded message: From: dennis malone (b)(6)> Date: March 11, 2020 at 6:35:32 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" ---------=-:-:-= CbH6) Subject: CORONA VIRUS DATA SUPPORTING PROACTIVE EFFORT Slr, I appreci ate the effo rt of your entire team in ident ificati on and reso luti on of the predicament the chinese government has gotte n us into. That said, I believe you might add a more proact ive edge by min ing existing data. You' re going to have to dig deep. It seems that the commo n denominator in originating vector, at least by your news releases, is plainly travel-related co-mingling of persons not otherwise in contact. There fore, l wou ld propose that there is a great trove of existing data waiting to be filtered within the travel manifest s' histo ry of US-bound airlines and US-bound cruise vessels. Suggest as a start the collection of every manifest from the last 4 months or so, filtered and compared with principl e contractees known to exist in the US , and list every other person on said aircraft/vessel that disembarked on US soil. DO NOT WAIT FOR PEOPLE TO GET SICK - Employ the National Guard and Coast Guard to track these folks and put a swab in their nose. If positive, the n contact trace this smalle r group. If nega tive maintain them on the list and force complian t reporting if they develop suspected symptoms. I know it would seem to be a lot of work. However, I presume your are familiar with the FRAM Oil Filt er Guy from the 1970s, where it's better to pay now than later because you're going to pay one way or another. Get a proac tive jump on DETECTIO N, IDE NTI FICATION , CONTROL. We're burning daylight. Respectfully submitted, Dennis J. Malone (b)(6) NIH-000679 (b)(6) NIH-000680 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 11 Mar 2020 23:10:18 +0000 To: Subject: Attachments : Sharon Cumbie Re: Need to add cell phone disinfecting to the hand washing messaging image.png, POSTING.jpg Than ks ! On Mar 11, 2020, at 6:46 PM, Sharon Cumbie ---------- CbH6)> wrote : Dr. Fauci, First , thank you for all you are doing to keep the publ ic infonned in a clear , direct , and truthful manner. I am writing to offer a suggestion. The following is a post I just p laced on my Facebook page: It's a 2-step process!!! We are seeing the ubiquitous pleas for proper hand-washing as a preventative against contracting the corona virus. BUT ...I have observed people doing a great job of hand-washing , then picking up their dirty cell phones!! The cell phone should FIRST be wiped down using a disinfecting wipe (do NOT use sprays or household cleaning supplies). After cleaning the phone , THEN do a proper 20 second hand-washing. Now, CARRY ON! Step 1: https://www. tomsguide.com /news/how -to-clean -your -phone-to -protect aga inst -coronav irus ?tbcl id=lw AR 1WHGawAANyt kUOSmSV2SM UcZ5776 l mAsp -XR.k:UEKDsl YhcLRKXFBOJ io Step 2: Proper Hand Washing Photo message montage : I hone-stly do not see people disinfecting their cell phone s. I am active in our Cb)(6) community and am trying to get this information across to people in the comm unity. They have told me it was helpful and something they had not cons ider ed. I tho ught it would be helpful for me to share with you . Best Regards , Sharon Cumbie ----- NIH-000681 Sharon Ann Cumbie, PhD, RN, CS, CNE (b)(6) Professor of Nursing (b) (6) Resea rch and Educa tion Cons ultant , Certifi ed Nur se Educator e.ptal l::lealth Csm ns_eJ_uo .,__~= (b)(6) Skype: _____ !&)\\et~LI'ldtt runnno wato, (b_H_6l b)~ ,.,.p3"drub PHnSIOQ911lOI 10 WUlO (Cl Sp,...u tM Lr.Mf IWff 1.1'» IWluSof the llilndl 1<$Mlk•S<.r~lh+so-,p !)'II In bot;>,_ Ul4fllgt(S compliw eor~• tI) ~/ PMIIC\lla(.ittae11on tolhe~ {9}Prffi t~ 11'1!0 l~ Pitit!I of ffeh 11.\/ld NIH-000682 !\) Olylhol:~wlCh dt~n 10'1 ,.l I From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:46 -0400 Eisinger, Robert (NIH/NIAID) [E) Fwd: Coronavirus Please handle Begin forwarded message: From: Terr i Davis (b)(6) Date: March 11, 2020 at 7 :04:02 PM EDT To: "Fauci , Anthony (NIH/N lAID) [E]" Subject: Coronavirus --------::-,--:=, --------- (b)(6) Dear Dr. Fauci; I live in (b) (6) Last week there was the first incidence of the Coronavirus. The officials in Media gave no true information on the individual but that it was a female. When questio ned by the press as to the locat ion in which the individual was - the respon se was that that information could not be given. [ have also heard that it is in a violation of a person's privacy. No one is asking for the person's name or address. If the public were given the general area of the affected person they would proba bly stay clear of the area. The people directly in the area wou ld be more cautious . Knowing where the person freq uented, for example, the market would be pertinent in preventing spread of this virus. There is so much information about this virus that is unknown yet most officials continue to underscore the severity of this v irus. Sincerely, Teni Davis Sent from my iPad NIH-000683 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 19:08:05 -0400 Cassetti,Cristina(NIH/NIAID) [E] Fwd:Applicationfor NIH and Dr. BruceAylward from W.H.O. Please handle Begin forwarded message: From: David Craig (b) (6)> Date: March 11, 2020 at 7 :05:42 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID ) [E]" (b)( > Subject: Re: Application for NIH and Dr. Bruce Aylward from W.H.O . Evening Dr. Fauci, My name is David Craig and I am one of the Founders of the Medsoft Group, a Analytics, Telemetry and Reporting medical platform out of Canada. We would like to offer our solution to the NIH free of charge, much like we have done with Dr. Bruce Aylward and the World Health Organizat ion earlier today. Our application will track, log and provide a pathway to true two-way real time communication of COVID-19 as citizens around the US report their symptoms on their mobile device . We are currently implementing our technology with our partners at the University of Alberta, but we would like to refocus our immediate attention in helping with the novel coronavirus . Deployment of our application would allow the NIH to manage and understand potential clusters and outbreaks of the pandemic, taking advantage of the estimated 96% of Americans that use a smart phone to easily record a potential case, providing all stakeholders across the US with the latest information. Medsoft Group is ready to offer th is immediately and without delay. With your cooperation we believe we could be up and running with in a week, providing th is invaluable too l to better understanding where and what the virus is doing around the country in real time. Please let me know if you would like to speak further. We would be happy to demonstrate our technology as well as discuss how we wou ld put this amb itious plan into place. Best, David Craig Co-founder &Ch ief Executive Officer Medsoft Group Inc. NIH-000684 C: CbH6)T: ------- (b)(6) U: www .medsoftqroup.com IMPORTANT: The contents of this email and any attachm ents are confidential. They are intended for the named recipient(s) only. If you have received th is email by mistake, please notify the sender immediately and do not disclose the contents to anyone or make copies thereof . NIH-000685 From: Date: To: Subject: (b)(6) Wed, 11 Mar 2020 18:35:29 -0400 Stephen Chiarello Re: Treatment of Corona virus Than.ks, Steve. l will fo1ward to my program staff > On Mar 11, 2020, at 6:22 PM, Stephen Chiarello > ___________ (b) ( __, wrote: > Anthon..y_: ___ ~~= > This is (b)(6) Stephen Chiar ello from (b)(6) _ I am a board-c ertifi ed de rmato Iogist and interni st. > > Justa brief note and certainly somew hat quixotic: The treatment of toxic epidermal necrolysis With TVvitamin C and th iamine (benfotoxamine) May well stop the cytoki ne casca de with the coronav irus. This was used Wayback in the po lio epidemic before the vaccine w ith great success but limi ted subscrip tion. > I 'll send you the references. > Sinc erely, > Stev e chiarello ----------- > > Sent from my iPhone NIH-000686 From: (b)(6) Date: Wed, 11 Mar 2020 18:34:29 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: Treatment of Corona virus To: Subject: Please handl e . Begin forwa rded message: From: Stephen Chia rello Date: March 11, 2020 at 6:22: 13 PM EDT To: "Fauci , Anthon y (NIH/N IAID ) [E]" ----------- Subject: Treatment of Corona virus ------~~ --------- Anthony: This is (b)(6) Stephen Chiarello from 1 am a board-certified dermatologi st and internist. ----- (b)( == > (b)(6J: ------------ (b)(6) Just a brief note and certa inly somewhat quixot ic : The treatment of toxic epide rmal necro lysis With IV vitamin C and thiamine (benfoto xamine) May well stop the cytokine cascade with the coronavirus. This was used Wayback in the polio epidemic before the vaccine with great success but limited subsc1i ption. I'll send you the references. Sincerely , Steve chiarello Sent from my iPhone NIH-000687 From: Date: To: Subject: Coronav irus Fauci, Anthony (NIH/N IAID) [El Wed, 11 Mar 2020 11:53 :45 +0000 Lerner, Andrea (NIH/N IAID) [El FW: From Whit Clark; possible theory and plausib le new thinking about a Please respond. Anthony S. Fa uci, MD Director Nat iona l Ins titute of Allergy and Infectiou s Diseases Buildi ng 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 Nationa l Institutes of Health Bet hesda, MD 20892-2520 Phone: (b) (6) FA X: (301) 496-4409 E- mail (b) (6) The information in this e-mail and any of its attachme nts is confidential and may contain sens itive infom1at ion . It should not be used by anyone who is not the original intended recipie nt. If you have received this e-mai l in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The Nationa l Institute of Allergy and Infectious Disease s (NJAlD ) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representa tives. -----Original Message----From: Whit Clark ,,,_..-----= (b,.,. )""' (6) =Date: Wednesday, March 11, 2020 7:39 AJ\'1 To: Fauci, Anthony (NlH/NlAlD) [E] (b) (6} Subject: From Wh it Clark; poss ible theory and plausib le new thinking about a Coronav irus --------=-=--:-= Jn Later November, After a discus sion with my daughte r yesterday (an Asst. Principal in (b)(6) area) , we theorized that the Co ronavirus May well have already been here before the close of 2019. China had likely had the outbreak begin much ear lier but neve r acknowledged it; peop le traveling to Chi na from the US could have returned and brough t the virus with them at a mu ch earlier date . When thinkin g about the numb er of peo ple my daughte r and I have known that bad a bou t of respiratory illnes s with a cough that cont inued much longer than the t)'p ical cold, we are propos ing a theory that possibly Coron a made its entry here much ear lier... .and this new expected outbreak may well be more of a contin uation and less threatening than possibly theo rized at this time. It is ju st a thought but I thought it was worth sharing. If true, we have already met the disease and the deaths attributed to "nom1al" flus and respiratory cau ses in the elderly and prev iously .impaired, may have been caused by Cor onavirus. This cou ld be a slight ly new twist and could pres ent a slightly lower concern for a new major outbreak. Just a thought ..... Whit Clark William W (b)(6) Sent from my iPhone NIH-000689 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:23:48 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: The Coronavirus Pis respond Sent from my iPhone Begin forwarded message : From: LAB (b) C Date: March 10, 2020 at 11:23:49 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: The Coronavirus --------::-:--:-= --------(b)(6) . Dear Dr. Fauci, My name is Sargon Gorjian and I am a research chemist at Clean Plus Chemical in S dne . Man ears a o I wa5 workin at Nanosonics com any in Sydney on (b) (4) I just wanted to share with you my experience with ----------this type of work. I would suggest to have a look at Virox Pat ents. It will not do any (b) (4) harm. It might be the right way to go. Sorry to take up your valuable time. I wish you all the best and good luck! NIH-000692 Regards Sargon Gorjian Laboratory Manager (b)(6) Stop the spread. Instant Hand Sanitiser Is an alcoholbased gel whichkills bacteria(99.9916)w,rhin 30 seconds, no washing or rinsing required. Testedand approvedaccordingto TGAmelhocl s. Glycerinmoisturiser& Vitamin E. icals Pty Ltd rge Young St . 44 444 F: 7 Contactus todayto placeyour orde,. s.co m Codt numbtr: 36430 (1211SOOmL ttN ) Any views expressed in this message are those of the 1nd1v1dualsender, except where specifically stated to be the view of the Company, its subsidiaries or associates. When addressed to our customers, any opinions or advice contained in this email are subject to the relevani Company terms of business ....... Plus Be earth -smart . Please con.sider the environment and cost of paper before you print. NIH-000693 From: (b)(6) Date: Wed, 11 Mar 2020 06:21:19 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: Breakthro ugh: Chloroquine phosphate has shown apparent efficacy in t reatment of COVID-19 associated pneumonia in clin ical studies Pis respond Sent from my iPhone Begin forwa rded message: From: RJ Claymont (b)( Date: March 11, 2020 at 4:22:35 AM ED T To: "Fauci , An thony (NIH/N lAID ) [E]" (b)(6) Subject: Breakthrough: ChJoroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies ---------=-:-:-= Dr. Fauci Just thoug ht I'd brin g this article to your attentio n. Are your rese arch ers trying Chloroq uin e? https://www.js tage.jst.go.jp /article/bst/advpu b/O/advpub _ 2020.0104 7/_artic le Best Regards RJ Claymon t NIH-000694 From: (b)(6) Date: Wed, 11 Mar 2020 06:20 :35 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: NIH ketone ester for Coronavirus treatment? To: Subject: Pls respond Sent from my iPhon e Begin forwarded message: From: Frank LLosa - KetoneAid (b) (6J Date: March 11, 2020 at4:14:0 8 AM EDT ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: NIH ketone ester for Corooavirus treatment? Dear Dr. Fauc i The re was a paper recently showing a ketogen ic diet helped tame the general flu, in mice. Meanw hile, there is a drink developed via DARPA and NI H (Dr Veech) that mimics the benefits of the diet. It is called a ketone ester. Even shown to block effec ts of nuclear bomb style radiat ion (LD-70 to 100% survival). Who can I soak to about te sting this drink on mice for the general flu , or even human s with Coronavirus symptoms? Can I send you the paper ? Thank you, Frank Llosa CEO KetoneAid (b)(6) NIH-000695 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:19:56 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fw d: Curevac, meeting w ith President Trump Please respond Sent from my iPhone Beg in forwa rded message: From: Ingmar Hoen(b)(6) Dat e: March 11, 2020 at 2:20 :51 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Cur evac, meetin g with President Trump -;;-c-;= (b)( Dear Dr. Fauci, I am the new CEO of CureVac. Would be good to update you on our efforts on Covid-19 vaccine here in Europe. This is a globa l challenge, we shou ld learn from each other to act fast and avoid mistakes . I do not accept any barrie rs from Stephane Banceljust for compe titive reasons. Happy to call or to mee t persona lly. Best regards, Ingmar Hoerr Gesendet iiber BlackBerry Work (www.blackberry.com) NIH-000696 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 06:19:13 -0400 NIAID Public Inquiries Fwd: Coronavirus bioweapon production method Sent from my iPhone Beg in forwarded message: From: Adam Gaertner (b) (6) Date: March 11, 2020 at 6:16:40 AM EDT ,------To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Coronavirus bioweapon production method --;;-~ (b)( Hello Anthony , This is how the virus was created . Inte rvirion Fusion. HIV-luc(ACE2) (500 ng ofp24) was mixed with 1,000 ng of p24 of HIV-gfp particles incorporating ASLV-A envelope, SARS-CoV S prote in, or both envelopes in PBS at 4 °C for 30 min to allow bind ing. Samples were ra ised to 37°C for 15 min to allow for conformational rearrangements. Virions were adjus ted to the desired pH with 0.1 M citric acid. PB S, TP CK-trypsin (final concentration 10 ~tg/ml), CTSL , cat hepsin B (CTSB) (fina l concentrations 2 ~tg/ml) or CTSL buffer alone was then added . Recombinant CTSL (R &D Systems) was preactivated by incubat ion for 15 min at 10 µg/ml in 50 mM Mes, pH 6.0, on ice. Recombinant CTSB (R &D Systems) was preactiv ated in 25 mM Mes, 5 mM OTT, pH 5.0, for 30 min at 25°C. After a 10-min incubation at 25°C, proteolysis was hal ted by the addit ion of 300 µ1 ofDMEMIO conta ining leupept in (25 µg/ml) and STI (75 µg/m l). Virions were then incubated at 37°C for 30 min to allow membrane fusion. 100 µl of the virion mix ture was added in quadrupl icate to HeLa- Tva cells pretreated for 1 h with leupepti n (20 ~tg/ml). The cells were spin-infect ed and inc ubated at 37°C for 5 h NIH-000697 From: (b)(6) Date: To: Subject: Wed, 11 Mar 2020 06:15:22 -0400 NIAID Public Inquiries Fwd: Prevalence of smoking, and reported mortality rates in COVID-19 Sent from my iPhon e Beg in forwarded message: From: Charles Kni ght (b) (6J Date: March 10, 2020 at 10:40:45 PM EDT To: "Fauci, Anthony (NIH/NlAID) (E]" (b)( Subject: Prevalence of smoking, and reported mortality rates in COVID-19 ,-------- ~= To whom it may concern: I assert that the frequency of clinically significant disease, as well as severe disease and morta lity of COVID -19 is much higher in smokers, as is the case with any pulmonary infection, such as influenza, or bacterial pneumonia. This is clearly in addition to that due to the prevalence of elderly and immunocompromised patient s; but smoking status overall may be a more significan t risk factor for clinically significant disease. In listening to the news med ia, smoking has not been addressed as a significant risk factor for disease. I would suspect that smoking is at least one reason that such a high mortality has recent ly been seen in Italy, and China, and I expect that mortality rates, as well as rates of clinically significant cases, will also be increased in other populations with increased prevalences of smokers, and strongly associated with the prevalence of smoking in the given population. Of course, the reporting of severe disease will be modulated by the effective ness of the given population in containing the virus) as well as the effective reporting of clinical disease within the community, whether severe or not. ln listen ing to the news media, smok ing has not been addressed as a significant risk factor for disease. I think that it should be addressed. One wonde rs if it could be a modifiable risk factor, at least in certain patients (such as those who have not smoked for very long). NIH-000698 One also wonders whether this could be another good prognostic factor for limited reported/ clinically significant cases (and thus limited perceived sprea d) in the United States, obviously in addition to our early, effective containment measures. Just thought this might be helpful. Dr. Charles W. Knight, MD Sent from my iPhone NIH-000699 From: Date: To: Cc: Subje ct: (b)(6) Wed, 11 Mar 2020 06:12:10 -0400 Lerner, Andrea (NIH/NIAID) [E) Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Covid-19 patie nt in hospital without negati ve pressure room Sent from my iPhone Begin forwa rded message: From: 00~ Date: March 11, 2020 at 3:53:18 AM ED T To: "Fauci, Anthony (NIH/NlAI D ) [E]" (b)(6) Subject: Covid-19 patient in hospital without negative pressure room --------=-=--= Hi Dr. Anthony Fauci , I saw you on M eet the Pr ess this weekend and you we re so awesome! Ve ry informative, calm, assuring but with the right amount of inst illing the need for us all to move fo1wa rd with the appropr iate caut ion for ourse lves. It's extreme ly reas surin g to have you leading and guiding us during this time . I'm emai ling you because I work at Kai ser Pem 1anente Hospita l in (b)(6) · Our administration init ially sa id if any Covid-19 patient came into the ho spital needing emer geny care and needing to be admitted they wou ld be given an N95 mask and put in a negative pressure room . Now they reve rsed that decision and said they'd be put in a regular positi ve pressure roomn even after I showed them the CDC's recommend ation for both co nfimed and possib le Covid-19 cases needing to be placed in negati ve pressure rooms /A IIR. Well tonight a possible Covid- 19 patient came to the Emergency Room and had to be admitted to the ICU. The patient was given ju st a regular mask and put in an elevator to the ICU . Management would not co nfi rm if the patient was in a negative pres sure room and wouldn't give staffN95 masks. I again showed them the CDC website hospital protocol Covid-19 recommendations but same response. And even was ye lled at by the hospit al nur sing superv isor for ask ing about it. I feel this is not safe at all for other patients , visitors and staff if the air is be ing recirculated not ven ted outside or through a hepa filter before recirc ulating back NIH-000700 through the hospital. I don't know what to do. Please help. The hospital main phone number is Cb)(6) the Chief of the hospital is Cb)(6) I know you're extremely busy now but any help or guidance is appreciated .. even if it's just to confirm that any confirmed or suspected Covid - 19 patient needs to be in a negative pressure room . Thanks so much! Sincerely, Kara Smalls NIH-00070 1 From: Date: Fauci, Anthony (NIH/NIAI0) [E) Wed, 11 Mar 2020 01:38:17 +0000 NIAID0DAM Fwd: Cancellation of 2020 Stanford Drug Discovery Symposium To: Subject: Sent from my iPhone Begin forwarded message: From: Joseph Wu Date: March 10, 2020 at 6: 11:52 PM EDT ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH6>: Cc: "David L.M.Preston" , Amanda Chase , Sanjay Malhotra Subject: RE: Cancellation of 2020 Stanford Drug Discovery Symposium ,..-..., •~ SDDS 2020 ,- -=~j !==. 111._ __,# I StanfordDrugOi$<;overy Symposium April 20-21, 2020 Dear Dr. Fauci, We greatly appreciate your willingness to participate in the 2020 Stanford Drug Discovery Symposium (SODS). As you undoubtedly know, with the further spread of the novel coronavirus COVID-19, Stanford is taking precautionary measures to minimize any preventable spread of this viral disease. After much consideration, we feel it is in the best interest of our speakers, guests, and community to cancel the April 20-21, 2020, symposium. We apol ogize for th e inconve nience this may cause in your sche dules . We do hope th at you will agree to be our gues t speaker NEXT yea r for our April 19-20, 20 21. As soon as your schedu le allow s, p lea se let us know if you would be able to s eak at our 2021 SDOS meet ing. NIH-000704 Please feel free to contact Dav id Preston preston@stanford.edu Amand a Chase chaseama@stanford .edu or myself joewu@stanford .edu if you hav e any qu estion s . or Thank you for your und erstanding, and we hop e to see you next ye ar. Lastly, THANK YOUfor all service to our country and for educating the public about the corona virus, we're a big fan of yours on all the news media. Sincerely, Joseph C. Wu, MD, PhD Sanjay Malhotr a, PhD Kuldev Singh, MD Mark Mercol a, PhD Joseph C. Wu , MD, PhD Director, Stanford Cardiovascular Institute Simon H. Stertzer, MD , Professor of Medicine & Radiology Stanford University School of Medicine 265 Campus Drive, Rm G1120B Stanford, CA 94305-5454 Ph: 650-736-2246; Fax: 650 -736-0234 Email: joewu@stanford.e du Tw itter: @StanfordCV I Lab Websi te: http ://wulab.stanford .edu Stanford CVI: http://med.stanford.edu/cvi .html Oi Stan £ord V Cardiovascular~ Institute , NIH-000705 From: Date: Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAIO) [El Tue, 10 Mar 2020 21:25:59 +0000 NIAIDODAM FW: Fields Symposium To: Subject: Patricia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases Th e National Institutes of Heal th 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The information in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please Inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: David Knipe Date: Tuesday, March 10, 2020 5:03 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)( > Subject: Fields Symposium ------ -=-<"= Dear Tony, I am sorry to write that we are going to have to cancel the Fields Symposium for April 24th, but we will re-schedule when we can. As you may know, Harvard has cancelled all meetings larger than 100 (and this morning limited that to 25) through at least April 30th. We are sad to have to do this, but we need to help mitigate the spread of the virus. Harvard even told the undergraduates today to go home this weekend and take their classes on line for maybe even the rest of the semester. Thank you for all you are doing to keep everyone informed about the coronavirus outbreak . We are going to give you the Harvard "Veritas " award when you are next here. Stay wel l. Best regards, David NIH-000706 David M. Knipe, Ph.D. Higgins Professor and Head, Program in Virology Dept. of Microbiology, Blavatnik Institute Harvard Medical School NRB Room 9508 77 Avenue Louis Pasteur Boston, MA 02115 Ph. 617-432-1934 Lab web site : htt p:/ /k nipelab.med .harvard .edu NIH-000707 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 17:56:17 +0000 Auchincloss, Hugh (NIH/NIAID) [C] FW: Funding, for Dr. Fauci --------~~ ------------ (b)(6) Please respond to thi s person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Rena Patel (b)(6)> Date: Tuesday, March 10, 2020 1:33 PM Tol (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E) Subject: Funding, for Dr. Fauci --------- (b)(6) Responsiveness to emerging infect ious disease threats is important. However, I worry that increasing funding is going away from global health priorities. It appears that the US Ending the HIV Epidemic has already diverted funding within NIH from global work to domestic . Will the NIH response to COVID-19 only worsen funding available for global health? Thanks, Rena Rena Patel, MD, MPH She/her Assistant Professor Division of Infectious Diseases, Dept . of Medicine International Clinical Research Center, Dept . of Global Health Email: (b)(6) Mobile : (b)(6) Skype: (b)( NIH-000709 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 10 Mar 2020 17:46:08 +0000 To: Gary Spinner RE: Testing for Covid-19 Subject: Gary: If you have the resources and capability to do it, you should. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Gary Spinner (b)(6) Date: Tuesday, March 10, 2020 1:45 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Testing for Covid-19 ------- --------- ~= (b)(6) Just heard your CROI talk. Thank you so much. Should we be testing for Covid-19 in patients with flu like symptoms in our Community Health Center by using commercially available tests for patients without history of travel or known contacts? We have two cases thus far in (b) (6) where my center is located. Gary Spinner Southwest Community Health Center Get Out loo k for iOS NIH-000713 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:26:19 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: asymptomatic infections of COVID-19 thelancetrm-5-20-00427 .pdf Please handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: 1iiJ ~ (b)(6)> Date: Tuesday, March 10, 2020 1:46 AM To: Fauci, Anthony {NIH/NIAID) [E]_______ (b =-,)..,. (6) = Subject: asymptomatic infections of COVID-19 Dear Prof. Anthony Fauci, At first, I express regret if I am bothering you in your busy schedule. I know you care about asymptomatic infection of COVID-19. COVID-19 is spreading rapidly all over the world, especially in Iran and Italy, and possibly even more widely. Asymptomatic infections and healthy carriers are possible sources for transmission. However, such sources of infection cannot be effectively identified due to the symptoms absent. The research evidence is ve1y lacking so far. (b)(4J NIH-000714 (b) (4) This encourages me to write to you to seek help! I will be mo st grateful if you could give us some suggustio n. Look forward to hearing from you soon, With kind regards, Your s sincerely, Yong He NIH-000715 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 16:21:12 +0000 To: Hahn,S tephen Cc: Redfield, Robert R. (CDC/OD); (b)(6) ;Cassetti, Crist ina (NIH/NIAID) [E];Marston, Hilary (NIH/N IAID) [E]; (b)(6);Conrad, Patricia (NIH/NIAID) [E];Graham, Barney (NIH/VRC) [E];Mascola, John (NIH/VRC) [E];Lerner, Andrea (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E] Subject: FW: Coronavirus test Attachments: nCoV-ColorimetriclAM P.pdf St eve: Let us discuss thi s whe n we are toge th er at t he 4:00 PM TF meet ing. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Roberts, Rich (b)(6)> Se nt: Tuesday, March 10, 2020 12:05 AM To: Fauci, Anthony (NIH/NIAID) [E] Subj ect : Coronavirus test ------=--c= -------- (b)(6)> Dear Tony: If you can find a few minutes, I would very much like to talk with you briefly about a new diagnostic LAMP test for coronavirus COVID-19 that we have developed here at NEB. I attach a paper now in the MedRxiv that briefly describes the test. It has been used already in Wuhan and because of its simplicity, speed and visual output we think it would be very useful for use here in the US. We have just met with several people at Mass General Hospital and wil l be working with them for local validation here in MA. The test itself is very inexpensive, does not require any special equipment nor train ing of technicians . This would appear ideal for the FDA and the CDCto know about, but I have not so far been able to reach NIH-0007 16 either Stephen Hahn or Robert Redfield . I would emphasize that our goals are to help deal wit h the humanitarian aspects of the current problems. I can be reached on my cell at ----- (b)(6) or in my office at the number below. Rich Sir Richard J. Roberts Ph.D. F.R.S. 1993 Nobel Laureate in Physiology or Medicine Chief Scientific Officer New England Biolabs 240 County Road Ipswich, MA 01938-2723 USA Tel: (b)(6) Fax: (978) 412 9910 emai l (b)(6) Executive Assistant: Tel (b)( ---- (b)(6) Fax: (978) 412 9910 emai l (b)(6) NIH-0007 17 From: Date: To: Cc: Subject: (b)(6) Tue, 10 Mar 2020 11:13:29 -0400 Cassetti, Cristina (NIH/NIA ID) [E] Auchincloss , Hugh (NIH/NIAID) [E] Fwd: Patented System - COVID-19 From P atty Pis respond. Sent from my iPhone Begin forwn rded me ssage: From: JOHN FLYNN (b) C Date: March 10, 2020 at 10:49:44 AM EDT To: "Fauci, Anthony (NIH/N JAID ) [E]" -------~~ _______ Subject: Patented System - COVID-19 (b_H_6J Dear Dr. Fauci, I know that you are extremely busy, but I would respectfully urge you to take 5 ruins. of your time to review the information below as I believe that I have a disruptive technolog y that can help prevent the spread of COVID-19. My name is John Flynn. I previously founded a startup medical equipment company that was focused within the area of orthop edics , wh ich I ran for twe lve yea rs. I ultimate ly sold the company to a pub lic competitor, DJO Global. I have worked on different healthcar e projects, but have exclusiv ely spe nt the last twenty month s focused on a new medica l product within the area of infection prev ention . My goal was to introduce what I believe is a disruptiv e product to help healthcare facilities to prevent the spread of MDRO's in order to reduce HAl's /SSl's; however , I believe that it can also help to reduce the spread of Coronavirus. (b) (4) NIH-000720 (b) (4) NIH-00072 1 (b) (4) NIH-000722 (b) (4) -------------------------you will have an intere st in further discussion . a Respectfully, John Flynn Cell: (b)(6) NIH-000723 Cb)<4> I hope that From: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 10:45:53 +0000 Houndsburgh RE:Thinking of you Date: To: Subject: Linda: Many thanks for your kind note. It is much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Iofectious Diseases Building 31, Room7A-03 31 Center Driv e, MSC 2520 National Jnstitutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) f AX: (301) 496-4409 E-ma il (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is nol the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Alle rgy and lnfectious Diseases (N1AID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives. ·-----------=.,..,.=- -----Original Message----from : Houndsburgh.,...,,.....,..,,..,...,.....,..,..-,-....,.----(b)(6) > Date: Monday, March 9, 2020 4:24 PM (b) (6) > To: Fauci, Anthony (Nlli/N IAID) [E) Subject: Thinking of you --------- Dear Dr. Fauci, You have been a bulwark for me since Twas a resident in the 1980s, dealing with the ATDS epidemic at LA County General. For so many years, you have prov ided expert guidan ce in a calm, rational manner. As the Coronavirw; becomes close r and closer to a pandemic, I know you have so much on your plate (hoarse vo ice, no? ). I sen d you my best wishes to stay well yowself during these trying times, and hope that you know how much you have meant , and continue to mean, to all physicians out there. You hav e given so much. May God bless you always. Best, Linda Schmidt, MD Internal Medicine NIH-000724 From: Date: Fauci, Anthony (NIH/NIAID) [El Tue, 10 Mar 2020 10:16:29 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E] Subject: FW: Predict the potential outbreak of COVID-2019 in the region based on the age information of reported COVID-2019 infected peop le Attachment s: COVID2019Prediction20200310.pdf, S1.xlsx FYI -----Original Message----From: (b) (6)> Senc: Tuesday , Marcb J0, 2020 5:21 AM To: Fauci , Anthony (NIH/NIAJD) [E] (b)( > Subject: Predict the potential outbrea k of COVTD-2019in the region based on the age infomiation of reported COVTD-2019 infected peop le ------. ~= Dear Prof. Anthony Fauci My name is Chao Wu and I am a research staff in national clinical research center for infectious disea~es. the first affiliated hospital of college of medicine of Zhejiang University of China . Based on the public data of COVID-2019 infected people in China, l have developed a simp le model to warn the potential outbreak of COVID-2019 in a region based on the age information ofieported COYlD-2019 infected people. Hope this could provide useful infonnationfor preventing COVI D-2019 spreading in US. And hope the two countries can be together to fight with COVID-2019 Best wishes! Chao Wu Room6A17 13 Qingchun Branch The First Affiliated Hospital of College ofMedicine of Zhejiang University. Hangzhou NIH-000725 From: Date: Fauci, Anthony (NIH/NIAID) [E] Tue, 10 Mar 2020 02:20:57 +0000 Eisinger, Robert (NIH/NIAID) [El FW: FW: Coronavirus Remote Monitoring image001.png , image001.png To: Subject: Attachments : Please take a look. From: ezriel kornel Cb)(6) Date: Monday, March 9, 2020 7 :10 PM To: Fauci, Anthony (NIH/NIAID) [Elr-----(b)(6) > --..(b.._.. )= c >; Auchincloss, Hugh (NIH/N IAID) [El Subject: Fwd: FW: Coronavirus Remote Monitor ing I think this may be a very valuable program . I have no involvement but was sent to me for my input . Ezriel Kornel, MD ---------- Forw arded message --------· From: King,Nicholas Date: Mon, Mar 9, 2020, 5:07 PM Subject: FW: Coronavirus Remote Monitoring To 00~ Hi Ed, I thought you'd find this to be of interes t. Greg is ~ (b)( ~ and I think the re may be an opportunity to help health agencies. Do you know anyone that this could be passed along to? Nicholas King Vice President - Financial Advisor T (b)(6) nicholas.king@bernstein .com 11 ::-c: After Arts Group I I Forbes From: Greg OKeeffe ------------ (b)(6) Date: Monday, Ma rch 09, 2020 9:05 AM To: King, Nicholas Subject: Coronavirus Remote Monitoring NIH-000726 External Email. Use caution when clicking links or opening file attachments. Nick, Following up on our conversation this weekend, I am including some information below about our Remote Patient Monitoring platform which we are making available for free to health agencies and organizations partic ipating in the response to COVID-19 in the United States. Remote Patient Mo nitoring with FollowApp is a HIPAA-Compliant system that helps health officia ls to diagnose, contain and treat this highly transmiss ible vira l threat by enab ling the effective screening of large numbers of potentia l patients and to triage/prioritize targeted clinical interventions including the use of test kits. FollowApp's monitoring dashboard and patient mob ile applications (iOS and Android) can be used to deliver two of the keys to an effective response plan: 1) encourage "self-qua rantin ing'' (a fundamenta l epidemiologic te net) and 2) off -load exploding cl inical volume threatening hospital Emergency Departments . Healthcare systems are thus able to maintain important contact with these populations and recommend targeted escalation of care when needed, while decreasing exposure to both clinicians and other patients. The public perception of the lethality of t his globa l pandemic is fueling panic wh ich, in and of itself, is creating its own logistic issues that are already beginning to overwhelm hospita l Emergency Departments. The dilemma for health care systems, then, becomes a question of identifying subpopulations at increased risk wh ile at the same time, keeping t hese patients out of the hospita l. Please feel free to forward this email along with my contact information (cell provide a demo to anyone who may be interested. ----- (b) (6)) -- I would be happy to Thank you again, Greg Greg O'Keeffe President & CEO Human Resolution Technologies, LLC www .Patient Monitor ing.com Linkedln The informa tion contained in this e-mail is legally privi leged and confidential information intended only for the use of the individual or enti ty to whom it is addressed. If the reader of this messageis not the intended recipient, you are hereby notified that any viewing, dissemination, distri bution, or copy of this e-mail messageis strictly proh ibited. If you have received and/or are viewing th is e-mail in error, please immediately notify the sender by reply e-mail and delete this email from your system. Thank you. e Virus-free. www .avast.com NIH-000727 For further important information about AllianceBemstein please click here http ://www .alliancebernste in.com/d iscla imer/ema il/discla imer .html IHI IHI BERNSTEIN BERNSTEIN NIH-000728 NIH-000729 BERNSTEI NIH-000730 BERNSTEI From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 02:19:50 +0000 Date: To: (b)(6) Subj ect : At tac hment s: FW: Revised Nursing Home Guidance QS020-14. COVID-19 Nursing Homes - REVISEDNIAID.docx I had my staff review this and their edits/suggestions are incorporated into the attached document. Best regards, Tony Disclaime r: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: CMS (b)(6) Se nt : Sunday, March 8, 2020 9:02 PM To: (b)(6) Fauci, Anthony (NIH/NIAID) [E] Subj ect : Fwd: Revised Nursing Home Guidance ---------- (b)(6) Would you mind reviewing our updated guidance to nursing homes? This is upgrading the policies around visiting etc . Would like to send this out tomorrow. Thanks. Sent from my iPhone Begin forwarded message: Fro m: "Shulman, Evan T. (CMS/CCSQ)"_________ _ )_ C_6)> Cb Dat e: March 8, 2020 at 8:52 :14 PM EDT To: CMS (b) (6)> (b)( >, "Brookes, Brady "Moody -Williams, Jean D. (CMS/CCSQ)" ;.,__.:....:......:.......!::::======~=;:--(b)( 6) >, "Wright, David R. (CMS/CCSQ)" Cc: "Hittle, Matthew (CMS/OA)" (CMS/OA)" ========::; (b)( , (b:;:: )(c"= 6>: ">-- Subject: Rev ised Nursing Hom e Guidan ce Seema, Attached is the Nursing Home memo with revised guidance (changes are in red/italics). This includes suggestions from Shari and Patti Meier, but they are still reviewing the full document. We sent this to the CDCthis afternoon and I just received their feedback (while NIH-00073 1 on this call). I skimmed through their feedback and while they recommended some changes, they did not suggest any substantive changes. Summary of revisions: (b) (5) We've also been in contact w ith the industry, and believe they will support the revisions . Happy to answer any questions . Thanks, Evan Evan Shulman Director, Division of Nursing Homes Quality Safety and Oversight Group Center for Clinical Standards and Quality Centers for Medicare and Medicaid Services NIH-000732 From: Date: To: Subject: Fauci, Ant hony (NIH/N IA ID) [El Tue, 10 Mar 2020 02:11:06 +000 0 Ma rston, Hilary (NIH/N IAID) [El FW: Coro navirus Case in Mu nich Please respond to this person . -------- From: Rita DiCasagrande Olsen Date: Monday, Mar ch 9, 2020 9:20 PM (b)(6) -------,;; ~ To: Fauci, Anth o ny (NIH/N IAID) [E] Subject: Coronavir us Case in M uni ch -------- (b)(6) Carissimo Dr. Fauci Greetings from Munich, Germany! It 's hard to believe so many years have passed since our t ime work ing avian influenza preparedness. I have watched every single interview during the past few months and I could not be more relieved to see you at the helm of this new, rapidly evolving crisis. I know you have very little time, so I will make this quick - hopefully to be followed by a more fulsome and proper hello. We have a prominent American businessman (age 64) here in Munich who tested posit ive a little over a week ago after skiing in the Dolomites in Italy. He has a history of respiratory illnesses, including double pneumonias and various other similar complicat ions. In short, he is sedated and intubated , and was placed on ECMOduring the past 24 hours. The team is administering ritonavir and lopinavir, as well as broad spectrum antibiotics. The German docto r here would like to acquire Remdesivir to have on hand if all other treatments fail. Because it is not being tested here, he inquired whether we could access it in the States. Would you be able to point me in the right direct ion for how, if even possible, we could transfer some to the Munich-based hospital here? Thank you so much in advance. Any other insights of course are certainly welcome. You continue to be a national treasure. All the best - Rit a NIH-000733 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Tue, 10 Mar 2020 02:09 :14 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Science of COVID-19 Curriculum? Please respond to him for me. Try to help him out. From: michael dispezio Se nt: Monday, March 9, 2020 9:16 PM ---------- (b)(6) To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Science of COVI0-19 Curriculum? Dr. Fauci, Twenty years ago, I wrote the US curricu lum "The Science of HIV" and we were honored to have you featured in our accompanying television broadcast, which was nominated for an Emmy (Discovery Channe l) . Years prior to that, I snagged my Masters from BU on some nove l, emergent retrovirus called HIV. Now , its time for me to do my magic and educate this new generation on COVID-19. This is a familiar audience (my people ), since most use the science programs I have authored fo r K-8 for the past 30 yea rs! How do I best proc eed with developing materials in sync with the national needs that demys tify the concepts sunounding COVID- 19? My skillset is in education, but my background in biology and biochem. Plea se Goog le me and/or check out the links below. https ://www.ns ta .org/recommendsN iewProduct Print.aspx? ProductlD = 1213 8 ht1ps:// www. hmh co.com /people /m ichael -dispezio NIH-000734 Sincerely, M ichael Di Spezio (anothe -------- Cb)< ) Virus-free. www .avg.com NIH-000735 Cc: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:58 :15 +0000 Collins, Francis(NIH/OD) [E);Trevor Mundel Dan Wattendorf;Jennifer Weisman Subject: RE: COVID-19 From: Date: To: Trevor: Ditto what Francis said. If Bill is seeing the VP tomorrow, he will surely bring it up to me at our 4:00 PM daily Task Force meeting. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis(NIH/OD) [E] Date: Monday, March 9, 2020 8:25 PM To: Trevor Mundel -----....Cb ~H;;: 6);;>------------ (b)(6)> ------- Cc: Dan Watt endorf --------=======- (b)(6) (b ~~::;; (6) :c;------ >; Fauci, Anthony {NIH/NIAID) [E) (b) (6>r>; Jennifer Weisman Subject: RE:COVID-19 Hi Trevor, Truly interesting opportunity. Tony is doing a media blitz (Sean Hannity on Fox right now) but I' m sure he will check in - and I would imagine that VP Pence will turn to him to decide how to respond to Bill' s phone call. Doctor-based testing capability in the US has gone up substantially in the last couple of days - after admittedly a rocky start. But home testing presents a novel detection scheme. I assume from what you say that false negat ives are uncommon and false positives are rare? NIH-000736 For Africa, this seems like a technology that ought to be deployed as soon as possible. It astounds me that there are no documented cases in East Africa yet-that defies everything we know about air traffic with China. Providing an opportunity for low -tech testing in Addis, or Kampala, or Nairobi, or Dar es Salaam seems like a highly desirable outcome. My two cents. Francis Date: Monday, March ----------------9, 2020 5 :57 PM -----~~ (b)(6) Cc: Dan Wattendorf ---------!:=====~=-..::~-----> (b)(6); From: Trevor Mundel To: Collins, Francis (NIH/OD) [E] ______ (b)(6)> Cb _H_6)>; Fauci, Anthony (NIH/NIAID) [E] Jennifer Weisman (b)( 6) Subject: COVID-19 Dear Francis, Tony, I wanted to give you a heads up on a call that Bill will have with Vice President Pence tomorrow around the COVID-19 sit uation. As you might be aware, we have been running an inf luenza transmission study in Seattle for the last 2 years. This involves at-home testing fo r ILi-symptomatic individuals (who log-in via a web app) and collection of nasal swabs, which are then sequenced for a range of respiratory pathogens . Dan can give you more details on this study if you have questions. When the Coronavirus situation arose, we added t his to the list of pathogens and hence were able to detect some of the early cases in Washington. The CDChas been very interested in the approach and at one point we had the highest screening capacity in the US (though only 400 samples per day, so I hope this is no longer true). At the same time, we have developed a COVID-19 at-home screening and information system with robust software that approximates what China was doing but also takes into account the opt-in requirements that are necessary in the US. We want to propose going beyond the Seattle area- this would be gated only by availability of testing. We can deploy this ready-now system more broadly in the US. Ideally we would also do a parallel outreach to some African countries. I'd be interested in your views and would be happy to jump on a quick call. Warm regards, Trevor Trevor Mund el, MD, PhD President, Global Health Program V (b)(6) F +1.206.494.7041 E ------------- (b)(6) NIH-000737 (b)(6) Executive Assistant Office of the President, Global Health V (b) (6) (b)(6) Bill & M elinda Gates Foundat ion www .gatesfoundation.org NIH-000738 From: Date: Fauci,Anthony (NIH/NIAID) [E) Tue, 10 Mar 2020 00:47:56 +0000 Del Rio, Carlos RE:[External] Re:Nice job in PressConference SSRN-id3549276.pdf To: Subject: Attachment s: Not for distribution. lt may still be under review Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7 A-03 31 Ce nter Driv e, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NJAlD) shall not accept liability for any statements made that are the sender's own and not expressly made on behalfofthe NIAID by one of its representatives. -----Original Message----- From: Del Rio, Carlos ------ (b ""),...(=6); Date: Monday, Ma rch 9, 2020 7:59 PM To: Fauci, Anthony (NlH/NlAlD) [E] -------=-=-:-= (b)( > Subject: Re: [External] Re: N ice job in Press Conference Share the Australian paper when you can. Could not find it. Carlos del Rio, MD. Sent from my iPhone > On Mar 9, 2020, at 7:54 PM, Fauci, Anthony (NTH/N[ATD)[E] > > Thanks, Carlos. --------- > >> On Mar 9, 2020, at 7:21 PM, Del Rio, Carlos ...______ >> >> >> >> Carlo s del Rio, MD . Cb _>_<_ wrote: >> Sent from my iPhone >> >> >> -------------- >> This e-mail message (including any attachments) is for the sole use >> of the intended recipient(s) and may contain confidential and >> privileged information. If the reader of this message is not the >> intended recipient, you are hereby notified that any dissemination, >> distribution or copying of this message (including any attachments) NIH-000739 (b) (6} wrote: >> >> >> >> >> is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the ori ginal message (including attachments). NIH-000740 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:30:13 +0000 M ichael Gerson RE: My column, just FYI Well done! Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui Iding 31, Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496-4409 -------- (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseas es (NIAID) shall not accep t liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by on e of its representa tives. -----Original Message----From: Michael Gerson--------(b ~)(= Date: Monday,Marcb 9, 2020 5:47 PM To: Fauci, Anthony (N1H/N1AID)[E]------~-~ ______ Subject: My column,just FYI _ )_(6) Cb _ https://www.washingtonpost.com/ opinions/ coronavirus-isnt-another-hurricane-katrina-itsworse/2020/03/09/25c302f2-6224- l l ea-acca-80c22bbee96f story.html NIH-00074 1 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 00:26:59 +0000 Mark Harrington ;Folkers, Greg (NIH/NIAID ) [El RE: NYC community letter to M ayor De Blasio on social distancing measure s to Date: To: Subject: mitigate COV ID-19 Tha nks, Ma rk. Goo d lett e r. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mark Harrington (b) < > Date: Monday, Ma rch 9, 2020 5 :42 PM To: Fauci, Anthony (NIH/NIAID) [E)______ --------=-:~ Cb _H_ >; Folkers, Greg (NIH/NIA ID) [El (b)(6)> Subject: NYC commun ity letter to Mayor De Blasio on social distancing measu res to mit igate COVID-19 At tached. Hope you're both we ll. cheers, Mark Mark Harrington Executive Director Treatment Action Group 90 Broad Street, Suite 2503 New York, NY 10004 USA (b)(6) - tel. NIH-000742 (b)(6) mark.harrington@ t reat ment act iongroup .org NIH-000743 From: Date: (b)(6) To: Subject: Mon, 9 Mar 2020 19:56:50 -0400 Eisinger, Robert (NIH/NIAID) [E] Fwd: Requesting a copy of your article Pis handle Sent from my iPhone Begin forwarded message : (b) (6]. From: MahendraDe Silva -----------Date: March 9, 2020 at 7:52:52 PM ED T To: "Fauci, Anthony (NIH/NIA ID) [E]" ---------=-:-:-= -------Subject: Requesting a copy of your article Cb)(6). Dear Dr. Fauci: Would you be kind enough to send me a copy of this important article (see below)? Thank you . Sincerely, MahendraDe Silva, PhD January 23, 2020 Coronavirus Infections-More Than Just the Common Cold Catharine I. Paules, MD1; Hilary D. Ma rston, MD, MPH2 ; Anthony S . Fauci, MD2 NIH-000744 From: Date: To: Subject: (b)(6) Mon, 9 Mar 2020 19:53:18 -0400 Krista Conley Re:Terry Beirn Kri sta: Many thanks for your kind note. Best rega rds, Tony __________ _, (b) (6) > wrote: > On Mar 9, 2020 , at 7:25 PM , Krista Conl ey > > Good evening Dr. Fauci: > > My name is Krista Conley and I was a staff assistant for Senator Kennedy's Labor and Human Resources Committee in 1987. I was supporting the committee on health-related issues until one day, this smart-aleck of a guy walked in and said "You work for me, now." > > That was Terry Beim, and I spent the next year ofmy life working on the very first legislation for research funding and for anti-discrimination protections. Terry made me better, stronger, more empathetic than I ever thought possible. He worked me relentlessly - and it never felt like work. Those were very tough times, and we never let up, not even to eat. > > I fielded a lot of calls from you to Terry , and seeing the coronavirus press conference tonight, I wanted to thank you for your tireless public health efforts. You changed lives to the good for millions - Terry did his bit, too. > > It' s good to hear your voice at the lectern - makes me feel like we'll get through it. Thank you for always jump ing in - Krista Conley NIH-000745 From: Date: (b)(6) Mon, 9 Mar 2020 19:43:06 -0400 Conr ad, Patricia (NIH/NIAID) [E) Fwd : The Economist Asks request for Dr. Anthony Fauci To: Subject: Let us discuss Begin forwa rded message: From: Sujata Thomas Date: March 9, 2020 at 7:41:03 PM EDT -------~~ To: "Conrad, Patricia (NIWNIAID) [E]" Anthony (NIWNIAID) [E]" Cb) C6>: CbH6J >, "Fauci, Subject: Re: The Economist Asks request for Dr. Anthony Fa uci Hi, I just wanted to follow up on this request for The Economist. The interview could happen at Dr. Fa uci's convenience. Th anks for the cons iderat ion. Best, Sujata On Thu, 5 Mar 2020 at 08:48, Sujata Thomas wrote: Dear Dr. Fauci, "The Economist Asks" , The Economist's award-winning interview podcast would love to have you join the program this spring. "The Economist Asks" is the Economist's flagship show , a current, frank and engaging profile-style interview , in a series that includes heads of state, cultural pioneers and business leaders, and hosted by Anne McElvoy . Anne wou ld like to discuss with you, your thoughts on coronavirus, its spread and the managem ent of this globa l public health emergency. We'd record 20 mins of interview, very flexible as to date and location though we'd love to do it soon - and are open to include subjects you feel NIH-000746 need to be covered. We know you are likely inundated with requests, so if you could connect me with the appropriate person handling your speaking requests, we'd greatly appreciat e it. Economist Radio has over 12 million listens a month worldwide , with a core audience in the US and the UK. Previous guests on "The Economist asks" include Melinda Gates, Tony Blair, Hillary Clinton , lmran Khan , Salman Rushdie, Annie Lennox , Anna Wintour, Darren Aronof sky, David Sedaris , David Mamet, Margaret Atwood, Ursula Burns , Juan Manuel Santos, Christine Lagarde, Jacinda Ardern, Michael Bloomberg, Pussy Riot, Pete Buttigieg among many others. You can listen to previous episodes here acast.co m/theeconom istasks . Thank you for your consideration and hope to hear from you or someone from your office . Thanks , Sujata (b)(6) This e-mai l may conta in confidential material. If you a re not an intended recipient , please notify the sender and delete all copies . It may also cont ain persona l views which are not the vie ws of The Economist Group . We may monitor e -mai l to and from our netw ork . Sent by a member of The Econom ist Group . The Group's parent co m pany is The Econo mist News paper Limited , reg istered in England with com pany number 236383 and registered office at The Adelphi, 1-11 J ohn Adam Street , London, WC2N 6HT. For Group company registration details go to http ://le gal.economist grou p.co m NIH-000747 From: Date: (b)(6) Mon, 9 Mar 2020 19:25:47 -0400 Nl;\JDPqhliC'lnquiries At.ithin d oss, Hugh (NIH/NIAID) [E] To: Cc: Subject: Fwd: (b)(6) Sent from my iPhone Begin forwa rded message: From: Laura (b)(6) Date: March 9, 2020 at 5:48:06 PM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" Subject: Still positive after 30 days --------=-=--:= --------- De_ar Dr:...£a uc.·._,, _______________________ (b)(6>f _, ...--,,., (b)(6) Thank you , Laura Umphries (b)(6) Sent from my Verizon, Samsung Galaxy smartphone NIH-000748 From: (b)(6) Date: To: Subject: Mo n, 9 Mar 2020 19:22:39 -0400 Auchincloss, Hugh (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Fwd: Testing for COVID-19 From patty Pis respond . Sent from my iPh one Begin forwarded me ssage : From: Robe rt Langston Date: March 9, 2020 at 6:38 :20 PM EDT To: "Fauci, Anthony (NIH/N IAID ) [E]" (b)( ---------=-=-:-= (b)(6) Subject: Testing for COVID-19 Hello Dr. Fauci, Are you able to provide false posit ive and false negat ive values for patients w ith Corona Virus infect ion and colonizat ion? Thank you fo r ta king t ime to read and respond my question . My regards, Robert Langston M D NIH-000749 From: (b)(6) Date: To: Subject: Attachments: Mon, 9 Mar 2020 19:21:36 -0400 Handley, Gray (NIH/NIAID) [E] Fwd: CoV collabo ration with Polish Medical Research Agency image00l.png From Patty. Does asf need to see this I am trying to empty his emails. Pls advise ASAP Sent from my iPh one Begin forwarded message : From: "Hand ley, Gray (NIH/NIAID) [E]" Date: March 9, 2020 at 6:51:14PM EDT To: --------------. (b)(6) CbH6) Cc: "Fauc i, Anthony (NIH/NIAID) [E] " CbH6) "Lane, Cliff (NIWNIAID) [E]" Cb>< , ''Auchincloss , Hugh (NIH/N IAID) ..... [E]" Subject: CoV collaboration with Polish Medical Research Agency ___________ Dear Dr. Sierpinski, Dr. Fauci referred your message to me and other NIAID colleagues with a request that we respond on his behalf so as to avoid further delay. We certa inly sympathize with your situation, as we also are working urgently to prevent, control and manage COVID-19 in the United States. During his visit to NIH in 2018, I was pleased to meet Minister Szumowski and, although I was traveling when you visited Dr. Fauci last year, I am aware that the meeti ng was productive and that we remain interested in encouraging further U.5.-Poland scientific collaboration . In part , as a result of that meeting, w e are also very pleased to be planning an NIH and ABM-sponsored clinical research training workshop in Poland later this year . As you are likely aware, NIAID is collaborating with a number of organizations to develop vaccines for SARS-CoV-2.We are expecting the first vaccine to start Phase I t rials within the next month . As vaccines move through Phase I testing, there may be opportunities to collaborate . In addition , with NIAID as the regulatory sponsor , we have initiat ed a rando mized, controlled clinical tria l to evaluate the safety and efficacy of the investigational antiviral NIH-000750 remdesivir in hospitalized adults diagnosed with COVID-19. This adaptive design trial w ill allow for t he addition of new treatment arms as promising new therapeutics fo r COVID-19 become available. Eventually, t his trial may be expanded to include international sites, potent ially includ ing some that have been affiliated with our INSIGHTNetwork in the past. Three sites in Poland have part icipated in INSIGHT trials: Site Name: Wroclawsk ie Centrum Zdrowia (Wroclaw) Sit e Leader: Brygida Knysz Site Name: Wojewodzki Szpital Zakazny (Warsaw) Sit e Leader: Andrzej Jerzy Horban Site Nam e: Uniwersytecki Szpital Kliniczny (Bialystok) Site Leader: Robert Flisiak It might be a good idea to let any Polish sites/investigators considering participation in this trial know that ABM m ight have available funding to support international collaborat ive research, if that is the case. This may be importan t info rmation as Polish scientists interact with other European scientists considering the development of a multi -site clinical tr ial. In addition, there may be other opportunities for collaborative research engaging Polish Institutions with accessto COVID-19 patients, particula rly through the sharing of biolog ical samples and research data. Another approach would be for interested Polish scientists to explore shared interests with U.S. colleagues who are planning to apply for COVID-19 funding in response to current Funding Opportunity Announcements in the NIH Guide to Grants and Contracts. To do what we can to facilitate possible collaborations, we would also welcome receiving additional information on specific COVID-19 research interes ts, capabi lities and activities current in Poland. Thank you again for reaching out to Dr. Fauci. We look forward to continuing to discuss potent ial areas of collaboration. Best regards, F. Gray Handley Associate Directo r for International ResearchAffa irs National Insti tute of Allergy and Infectious Diseases National Insti tute of Health U.S. Department of Health and Human Services ----- (b)(6) Tel: Fax: 301 480 2954 5601 Fishers Lane, Room lESO Bethesda, MD 20892-9802 (b)(6) Disclaimer: The info rmation in this e-mail and any of its attachments is confidential and may conta in sensitive info rmat ion . It should not be used by anyone who is not th e origina l intended recip ient . If you have rece ived this e-mail in error please inform the sender and delet e it from your mailbox or any ot her storage devices . Nat io nal Institute of Allergy and Infectious Diseases shall not accept liability fo r any statements made that are sender's ow n and not expressly made on behalf of the NIAID by one of its representat ives. NIH-00075 1 --------------------="'""""=-- From: Radostaw Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NIAID) [El" Cc: "Gupta, Ranjan (NIH/FIC) [E)" (b)(6)> CbH6)> ;....:..-======~~~ (b)(6) --------- Subject: CoV collaboration w ith Polish Medi cal Rese arch Agency Dear Doctor Fauci, I hope this e-mail is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly with general society wo rries than epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project . On behalf of Polish Minister of Health Prof . Lukasz Szumowski I would like to kindly ask you for some support and collaboration options with NIH in this very del icate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, Radostaw Sierpinski MD , PhD Preside nt of M ed ical Research Agency in Polan d (b)(6) M edical Research Agency ul. S. Moniuszki 1A 00-014 Warszawa www .abm.gov.pl AGENCJA BAOAN MEDYCZNYCH NIH-000752 AGENCJA NIH-000753 BAOAN MEOYCZNYCH From: Date: To: Subject: Attachments : Conrad, Patricia (NIH/NIAID) [El on behalf of Fauci, Ant hony (NIH/NIAID) [El Mo n, 9 Mar 2020 20:13:17 +0000 NIAIDODAM FW: Opp to speak to U.S. CEO Commun ity CEOoverview _updated_5_31 _19_ (1) (2).pdf Patr icia L. Conrad Pub lic Health Ana lyst and Special Assistant to the Direc tor Nat ion al Inst it ute of Aller gy and Infectious Disease s Th e National Institutes of Heal t h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer : The informat ion in this e-ma il and any of its attachments is confidentia l and may conta in sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA i D by one of its representatives. From: Greg Reilly Date: Monday , March 9, 2020 4:06 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: Opp to speak to U.S. CEO Community (b)(6J> Dr. Fauci, Our national radio and magazine audience is the U.S. CEOcommunity, and th is is an invitation to be interviewed for The CEOShow and The CEO Forum Magazine. The opportunity is to deliver your words directly, verbatim , with no reporter's interpretation. [Company Overview attached.] The line of questioning would be about advice for corporate leaders during a health crisis, such as we are experiencing now with COVID-19 and such that we may experience again in the future. We could do the 19-minute interview by phone or in person in New York City. Certainly w e honor your service and excellence as a spokesperson. Our out lets would be effective fo r your messages specific to business leaders. Please consider this invit ation. NIH-000754 Thank you Greg Reilly Greg Reilly I Associate Publisher (b)(6) I greg@theceoforumgroup .com ----- I www .t heceoforumgroup.com NIH-000755 Fauci, Anthony (NIH/NIAID) [E) Mon , 9 Mar 2020 18:23:56 +0000 Tabak, Lawrence (NIH/OD) [E) (b)(6) Marston, Hilary {NIH/NIAID) [E] RE:Appropriations - second supp for cornavirus - professiona l judgement From: Date: To: Cc: Subject: ·------- request W e w ill have additi onal needs. Wil l get back to you tod ay about th e amou nt and wha t th e plan is. Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . CbH > From: Tabak, Lawrence (NIH/OD) [E] Date: Monday, March 9, 2020 1:01 PM -----~~ To: Collins, Francis (NIH/OD) IE) (b)( > ------- CbH6J>; Fauci, Anthony (NIH/NIAID) [E] Subject: FW: Appropriations - second supp for cornav irus - professional judgement request Import ance: High How do you want this approached please? Thanks Larry From: "M itch ell, Michelle (NIH/OD) [E]" CbH6J> Date: Monday, March 9, 2020 at 12:43 PM CbH6)>,"Shapiro, Nei l (NIH/OD) [El" (b)( >, "Hallett, Adrienne (NIH/OD) [E]" CbH6),"Higgins, Lauren (NI H/OD) [El" CbH6) Cc: "LaMontagne, Karen (NIH/OD) [El" CbH6)>,"Bauer, Jenna (NIH/OD) To: " Tabak, Lawrence (NIH/OD) [E)" NIH-000756 [E]" Subject: Appropriations --------- (b)( > - second supp for cornav irus - professional judgement request Hi everyone, Jen Cama wit h DeLauro just reached out to request our professional judgement on a second supplemental for the coronavirus . Below is her questio n. Would you let me know what I should tell her? Question: Does NIH, in its professional judgment, recommend any additional funding for coronavirus? Thanks. Michelle NIH-000757 From: Date: (b)(6) Mon, 9 Mar 2020 13:49:31-0400 Oplinger, Anne (NIH/N IAID) [E] Fwd : M ed ia Request: CBC News To: Subject: From Patty pls decline Sent from my iPhone Begin forwarded message: From: Adam Miller Date: March 9, 2020 at 1:44:59PM EDT -------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" Subject: Media Request: CBC News --------- CbH6J Hi Dr. Fauci, I'm a senior journalist with the health unit at Canada's public broad caster, CBC News, and I'm hoping to speak with you for a national story on COVID-1 9 preparedne ss in th e U.S. and Canada. I'm wondering if you'd be free for a brief phone interview on how prepared the U.S . bas been through out this outbreak and wha t further efforts need to be taken. Thanks , I would only need five minutes of your time by phone. Best, Adam Adam Miller Senior Writer CBC News Desk: 416-205-5719 Cell: Cb> (6) Twitter: @adams miller NIH-000758 From: Date: (b)(6) Mon, 9 Mar 2020 13:23:24 -0400 NIAID Public Inquiries Fw d: Celiac and Coronav irus To: Subject: Pls handle Sent from my iPhone Beg in forwa rded message: From: Ten ley W illock (b)(6) Dat e: March 9, 2020 at 1:00: 11 PM EDT ,------To: "Fauci , Anthony (NIH/NlAID) (E]" -;;-c-;= (b)( Subject: Celiac and Corona virus Hello Dr. Fauci, I am a teac her from --(b~ in a school district that closed this week due to the vim s scare (b)(6) I am >< years old and I have (b)(6) What is my vulnerabi lity to getting this virus teaching around young children. I know you have mentioned heart issues and chemothera py. Can you please give me advice? Tha nk you so much! Thank you for your hard work! Sincerely, Tenley Willock (b)(6) NIH-000759 From: Date: (b)(6) Mon, 9 Mar 2020 13:22:31 -0400 Haskins, Melinda (NIH/NIAID) [E];Selgrade, Sara (NIH/NIAID) [E] Barasch, Kimberly (NIH/NIAID) [C] Fwd: Senator Barbara Boxer To: Cc: Subject: Pis advise. Set this up? Sent from my iPhone Begin forwarded message: From: Nicole Burak (b)( Date: March 9, 2020 at 1:18: 11 PM EDT To: "Fauci, Anthony (NIH/NlAID ) [E]" Subject: Senator Barbara Boxer Reply-To: (b)(6). ________ --------=-=--= _, (b)(6) Dr. Fauci - my name is Nicole Kaneko and I work for Senator Barbara Boxer from California . I know the Senator is (b)(6) and she is hoping you may have a few minutes to talk to her via phone regarding an exciting way to test for the COVID-19 virus. Thank you in advance . Nicole Kaneko (b)(6) NIH-000760 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:19:45 -0400 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Virus Transmission From P atty Not sure who responded. Canu take this repeat email. Sent from my iPhone Begin forwarded message : From: DANIEL GAGNON Date: March 9, 2020 at 1: 16:07 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: Fwd: Virus Transmission (b)(6) ------------------=-::-:-= -------- (b)( > Dr. Fauci: I appreciated your office calling me last Thursday regarding my email concern below on the CoYid 19 virus epidemic. The fact that China has a larger percen tage of smokers in its population may have something to do with the faster spreading of the virus ther e. Male smoke rs out number females by a huge number and are there fore dying in much higher numbers because of that fact. Has anyone at CDC look ed into when a pe rson is around cigarette smokers that the particles of smoke land onto a persons clothing . That person then comes home with those smoke particles on their clothing and they can be shed when the clothes are removed from their body thus placing the possible virus laden particles back into the air at home to infect others. Just smell your clothes the next day and you can no doubt sme ll smoke on them . Has this case in point been looked into as a possible means of spreading the virus? Since a side effect of the virus is the patient developing pneumonia wou ld giving an elderly person the Prevar 13 shot help streng then their immu ne sys tem before the virus ever strike s them? I wish you &other virologist God Speed with finding a vacc ine that will stop the spread of this epidemic. Dan iel Ga non (b)(6) NIH-000761 Begin forwardedmessage: From: DANIEL GAGN ON Subject: Virus Transmission Date: Februar y 24, 2020 at 3 :48:33 PM EST To: CbH6 ) ----------- (b)( > Hi Dr. Fauci: I have been a long time admir er of you in the field of modern med icine. This ques tion I have re lates to the current Coronavirus circu lating around the world. For many years I have infom1edpeople that the ways a virus can be passed from person to person isn't always by a sneeze, cough or by touching someones face with their hands. Has anyone in your medica l community thought tha t if someone were smok ing and was an infected person that once they expel the smoke particles into the air tha t those micro smoke particles may contain vi.ruses tha t were in the respiratory system of an infected person. Everyone I mention this to don 't believe that this is possib le. What are your thoughts on this matter? If so why hasn't the medical communitywarned the public about this possibility as I stay away from all establishmentsthat allow smoking on their premises. Thank you, Daniel Gagnon (b)( 6) NIH-000762 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:18:14 -0400 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Question re: coronavirus infection & pneumococcal vaccination From patty Can one of you pls respond. Thx Sent from my iPhone Begin forwarded message: From: Manon Cox (b)( Date: March 9, 2020 at 1:06:33 PM EDT To: "Fauci, Anthony (NIH/NIAID) [E]" (bH 6J Subject: Question re: coronavirus infection &pneumococcal vaccination --------. ;..,...,-= Dear Dr. Fauci, This is Manon Cox, former CEOof Protein Sciences, the developer of Flublok® . First of all I would like to thank you for your realist ic comments around the ongoing coronavirus outbreak. I am glad to see that not everyone is presenting a "Spanish Flu"- like scenario. I am reaching out to you b/c I am noticing that so many people including professionals (MD's!) appear to be think ing that people with a coronavirus infection are dying from a cytokine st orm whereas my understand ing is that pneumonia (whethe r viral or bacterial) is generally the underlying of the lung failure. My question to you is: Do we know whether people that have previously received a pneumococcal vaccinat ion might be better protected from death after contracting a severe coronavirus infection? i.e., would it be possible that the coronavirus causes tissue damage resulting in a secondary pneumococcal infection? I know bette r than anyone (afte r work ing over 15 years on Flublok approval) that it is not realistic to expect a coronavirus anytime soon but if we could message that a pneumococcal vaccine could be beneficial in ultimate outcome it would be good for vaccines in general as we do have pneumovax and Prevnar available. Thank you for your consideration. NIH-000763 Kind regards, Manon Cox Sent from M ail for Windows 10 NIH-000764 From: (b)(6) Date: To: Subject: Mon, 9 Mar 2020 13:16:15 -0400 Oplinger, Anne (NIH/N IAID) [E] Fwd: Time for an interview w ith Ame rica Magazine? This is from patty Pis decline. Sent from my iPhone Begin foiwarded message: From: Kevin Clarke Date: March 9, 2020 at 1:07:02 PM EDT To: "Fauci, Anthony (NIH/NIA ID) [E]" CbH6J Subject: Time for an interview with A merica Magazine? ------- --..-. --, Dear Dr. Fauci, America magazine is the flagship effort of America Media in New York. We are a min istry of the Jesuits of the United States and Canada. America magazine may be the best known Catholic publication in the United States, publish for more than 100 years . I realize you must be supremely busy under the circumstances, but I thought I would ask if you could spare a few minutes for an interview in New York, over the phone or on remote via Skype for one of our internet programs to talk about the co ronavirus landfall here in the United States, how the public can best respond. We would also love to hear how your faith is helping you cope personally, perhaps how your Jesuit background is assisting your decision-making in this drama. Let me know if you think anything might be possible. Thanks, Kevin Clarke Kevin Clarke Senior Editor and Chief Correspondent 1212 Sixth Ave, 11th Floor New York, NY 10036 Phone : 2 12-515-0130 (office) NIH-000765 Phone : (b) (6) (mobile) Phone (b)( (Friday) Email: clarke@americamedia.or g Web: www. americamedia.or g America1 11~.Ri!~ Jo in the conversation: Twitt er I Facebook I YouTube NIH-000766 I Tumbl r From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 16:07:16 +0000 Alison Galvani RE: In press paper about impact of travel restrictions attached Thanks, Alison . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Alison Galvani Cb)(6) Se nt: Tuesday, March 3, 2020 4:04 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: In press paper about impact of travel restrict ions attached -------~~ Hi Tony, It may not be as pertinent as it was w hen we subm itted it, but I thought you might be interested in our modeling on the global spread of COVID-19. It is in press at PNAS. We also have a paper submitted to them about ICU and ventilator inadequacy in the US. I'd be happy to send it to you now or wait until after the peer-review process . Thank you for everything you do to lead us th rough these crises. All the best, Alison Alison Galvani, PhD Director , Yale Center for Infectious Disease Modeling and Analysis (CIDMA) NIH-000767 Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p:// cidma .yale.edu/ NIH-000768 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 16:02:31 +0000 Jacquelyn (Jackie) Madry-Tay lor RE: Dr. Marilyn Madry Lightfoote Thank you . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------------~~ From: Jacquelyn (Jackie) Madry-Taylor Date: Tuesday, March 3, 2020 11:04 AM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Dr. Marilyn Madry Lightfoote -------- (b)(6)> (b)(6) Good Morning, Dr. Fauci, I am CbH6) Dr. Jacquelyn Madry-Taylor. I know she would want me to congratulate you on the outstanding information you are providing the nation about the Coronavirus. The success of CbH career was directly related to you allow ing her to work in your labs as she began her career in molecular immunology . Your name was mentioned quite frequently during those early years and throughout her work in the federal government. I, CbH6)and othe r fam ily members miss her so much and know that she would be on top of the information about this new virus as you present it. Thank you so much for being such a cata lyst for her success and we applaud your efforts in identifying the source of the virus and finding a vaccine. Sincerely, NIH-000769 Jacquelyn Madry-Taylor , EdD NIH-000770 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 13:18:02 +0000 Kate Dickman RE:Thank You Tha nk yo u! Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . ---------________ --------:a ~aa, From: Kate Dickman Date: Monday, March 9, 2020 9 :00 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Thank You (b) (6) > ,. (b)(6J> Dear Dr. Fauci, I have been reading about your efforts to learn quickly about COVID-19, and subsequently educate the American public about its risks. I wanted to say how grateful I am for your expertise, perseverance and candor. Updates about what Americans should do to keep safe, and understanding what may be deemed risky for personal and community health, are greatly needed in these days of information (and possibly misinformation) overload. Giving American people current information and clear, updated guidance is the best way to create grassroots, coordinated, widespread effort, while the CDC,NIH, and other government health organizations organize the tops-down approaches to regional screening, emergency care, and COVID-19 research/testing for hopeful vaccination or treatment protocols . I'm very relieved and assured to have strong voices of reason, experience, and merit helping 'us' navigate these murky waters . I'm grateful for your courage. Thank you again. Kate Dickman NIH-00077 1 (b)(6) resident of ------- Cb)(6) Northern California Sent from Postbox NIH-000772 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 M ar 2020 12:57:57 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Containment Measures Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Alex Wolf, Esq. (212)717-2 510 Date: Monday, March 9, 2020 8 :43 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E (b)(6) Subject: Containmen t Measures Dear Dr . Fauci, Why doesn't CDCcounsel entire country on need for conta inment measures as indi cated by t he follow ing study: black box appears in ori . NIH-000773 Rapid Response was Crucial to Containing the 1918 Flu Pandemic Historical Analyses Help Plan for Future Pandemics. (b)(6) Would you know whether pulmonary sarcoidosis which has been in remission for years without medication puts one at greater risk of Covid-19 hospitalization as an underlying condition, or would only be higher risk if it was active and one was taking immunosuppressive drugs? Thank you. Alexander Wolf, Esq. 60 East 42nd Street Suite 4600 New York, NY 10165 (b)(6) NlH-000774 From: Date: To: (b)(6) Mon, 9 Mar 2020 06:49:10 -0400 Handley, Gray (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) (E];Barasch, Kimberly (NIH/NIAID) (C];Erbelding, Emily (NIH/NIAID) (E];Lane, Cliff (NIH/NIAID) (E] Subject: Fwd: CoV collaboration with Polish Medical Research Agency Gray: Please work with Emily to see what we can do for this person, if only with advice. Thanks , Tony Begin forwarded message: From: Rados law Sierpinski Date: March 9, 2020 at 6:42:08 AM EDT To: "Fauci, Anthony (NIH/NWD) [E]" Cc: "Gupta, Ranjan (NIH/FIC) [E]" _______ Cb>< --------. .--.,-,-= _ Subject: CoV collaborationwith Polish Medical Research Agency Dear Doctor Fauci, I hope this e-mai l is finding you well and your efforts in fight against Coronavirus epidemics is giving some effects. As you know in Poland we have currently 15 cases of CoV infection and we are also fighting mostly w ith general society worries t han epidemics. We would like also to take part in research on CoV vaccine or drug and Polish Medical Research Agency is planning to start financing some project on it as soon as possible. Both polish medical universities and institutes are fully prepared to take part in such project. On behalf of Polish Minister of Health Prof. LukaszSzumowski I would like to kindly ask you for some support and collaboration options with NIH in this very delicate issue. Maybe NIH can take some advisory role in our scientific project or Polish scientists may take some part in your work bilaterally . Looking forward to hearing from you, RadosfawSierpinskiMD, PhD President of Medical ResearchAgencyin Poland (b)(6) AGENCJA SADAN MEOYCZNYCH NIH-000775 Medical ResearchAgency ul. S. Moniuszki lA 00-014 Warszawa www .abm.gov.pl NIH-000776 From: Date: To: Fauci, Anthony (NIH/NIAID) [El Mon, 9 Mar 2020 09:57:48 +0000 Cassetti, Cristina (NIH/NIAID) [El Cc: Subject: Attachm e nts: FW: Connecting with Tony Fauci Baricitinib as potential treatment for 2019-nCoV acute respiratory disease .pdf (b)(6J Please take a look and respond -----Original Message----From: Collins, Francis (NTH/OD) [E] (b)(6) > Date: Monday , March 9, 2020 5:29 AM To: Fauci , Anthony (NTTI/NIAID) [E] (b)( >; Erbelding , Emi ly (NTTI/NlAlD) [E] (b) (6) >; Austin, Cb ristopher (NIH /NCA TS) [E] (b) (6) -=-....,,,,-,--,-..,,...---,,...,.,,,,.._ Cc: Tabak, Lawrence (NIH /OD) [E) (b) ( Subject: FW : Connecti ng with To ny Fauc i ------~~ Passing this on in case Bill Chin's idea mignt be of interest. Franc is -----Original Message- ---From: William Chin ________ (b_)~( = > Date: Sunday, March 8, 2020 10:48 PM To: Collins, Francis (NIWOD) [E] Cc: Baker, Rebecca (NIH/OD) [E] _______ (b_) _(6J _, ; Roger Glass ________________ Subject: Connecting with Tony Fauci ------~~ ; Austin, Christop her (NIH/NCATS) [E] (b_) _(6J _, Hi Francis et al, I write to get a message to Tony, who clearly is on the COVID -19 front lines of these days and "everyw here." At this early stage , you may agree that it is possible tha t containment and/or mitigation will not completely solve the current pandemic . Instead, effect ive treatmen t or amelioration of the worst complications is necessary. 1nthis spirit, I have an idea that was spurred by a letter in Lancet last month authored by Al Benevolent (attached ). In this com munication they suggest that baricitinib (Oluminant ; a JAK1/2 inhibitor regis tered by Lilly for the treatment of rheumatoid arthritis ), using in si lico techniques . might be useful in the treatment adva nced COVID - 19 pneumon ia/ ARDS identified . Baric itinib could possibly blunt the cytokine storm seen in the most severely affected patient s via inhibiti on of JAK 1/2, but also decrease viral en try in AT2 pulmonary cells and my ocard ial cells via inhibition ofGAK and AAKI. It is has a relatively short plasma half-life and hence could be mo re useful than Roche 's tocilizumab / Actemra). Baricitinib has a good safety profile although as a drug to treat autoimmunity it is fonnally contraindicated in patients with infections, this could be offset by treatment patients with anti-viraJs such as Gilead's remdesivir, etc. Perhaps you folks have already thought about/discus sed its use bu t if not J' d like a chance to chat about my additional thoughts. Thanks. Bill NIH-000777 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 03:10:28 +0000 Glenda Gray;Rancourt, Anne (NIH/NIAIO) [E];Dieffenbac h, Carl (NIH/NIA ID) [E] RE: 'You don't want to go to war with a president' To: Subject: Thanks, Glenda! From: Glenda Gray Se nt: Tuesday, March 3, 2020 9:37 AM _________ ..... To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (6) = >; Rancourt, Anne (NIH/NIAI D) [E] Dieffenbach, Carl (NIH/NIAID) [E] (b)(6) Subj ect : FW: 'You don't want to go to war with a president' (b)(6)•>; DearTo ny wonderful art icle, proud to be associated with you Subject: 'You don't want to go to war with a president ' https ://www .polit ico.com/ news/2 020/ 03/ 03/a nt hony-fauci-trump -coronavirus -crisis-118961 regards Glenda Glenda Gray President & CEOSouth Afr ican Medical Research Council : Executive Management South African Medical Research Council Tel: +27 21 9380905 I Cell: Francie van Zij l Drive, Parow Valley (b)(6) I Cape Tow n I Western Cape ww w .sam rc.ac.za saMR9 i I YEARS 19 9-201 9 &l Disclaimer - The information contained in this communication from the sender is confidential. [t is intended solely for use by the recipient and others authorized to receive it. lf you are not the recipient, you are hereby notified that any disclosure, copying, distribution or taking action in relation of the contents of this information is strictly prohibited and may be unlawful. This email has been automatically archived by Mimecast SA (Pty) Ltd This e-mail and its contents are subje ct to tbe South African Medical Research Co unc il e -mail legal 11oticeavailable at http ://www.samrc .ac.za/about/ EmailLcgalNoticc .htm. NIH-000778 From: Date: To: Subject: Linda; Thanks for the note. Tony Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 03:04:02 +0000 Birnbaum, Linda (NIH/NIEHS) [VJ RE:Thank you I wou ld cancel if I were you . From: Birnbaum, Linda (NIH/N IEHS) [V]________ Date: Sunday, March 8, 2020 1:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ----Subject: Than k you Cb _)_C6) _, -= (b=H=6J> Hi Tony, Just wanted to say thank you as a fo r mer colleague and friend for speak ing truth to power during this coronavirus crisis. So, am I right in thinking t ravel ing to California for my major science meeting and some university lectur es in a week should be canceled? I am, (b)( ~ Thx Linda NIH-000779 Fauci, Anthony (NIH/NIAIO) [El Mon, 9 Mar 2020 02:59:07 +0000 Thomas R. Frieden RE: FYI - guess which (b)(6JIwas thinking of .... From: Date: To: ---- Subject: Great article. Glad to be the anonymous subject of your discussion. Q From: Thomas R. Frieden (b)(6) Date: Sunday, March 8, 2020 3:32 PM To: Deborah Birx (b)( ; Deborah Birx CbH6J;Fauci, Anthony (NIH/NIAID) [El (b)(6J;Redd, Stephen (CDC/DDPHS.':": IS:-: / -:0 -:D-:. ) ==== (b ~),,..,. (= >; Schuchat, Anne MD "'.'" (C--D-C-:/0- D -.,====~ (b-)(= > Subject: FYI - guess whic li.___ _ )_(6) Cb ...i I was thinking of .... New article re nursing home restrictions and more here. (b)( > From: Tom Frieden Date: Sunday, March 8, 2020 at 2:35 PM To: Tom Frieden (b)(6) Subject: Nursing homes are ground zero for COV ID19 -- and what more we can do to save lives in the pandemic Dear Colleague, Two weeks ago it was clear that COVID-19 would become a pandemic , and, sadly it has. Now the United States is in the acceleration phase and cases, clusters, and large outbreaks will occur in many parts of the country. I outl ine steps we can take to reduce the harms. The core concept to protect the most vulnerable. First, restrict visits to nursing homes. All of us can play a part reducing infections. Medically vulnerable people can protect themselves by reducing social contacts . I'm not sure I'd go quite as far as my good friend Bill Schaffner and say they should become semi-hermits . but that 's certainly a helpful frame of reference. Health care needs to get much safer, and ready to surge safely. And we need to stop mass gatherings, consider telework, figure out whether closing schools will help, and more. Read what I've posted about ground zero in the COVID-19 pandemic in the US here . I've shared on Twitter if you'd like to disseminate. We'll all be working together to protect as many people as quickly as possible . Thank you, Tom NIH-000780 Tom Frieden, MD, MPH President and CEO (b)( t TOSAVE LIVES ANlfllTIATIVE OFVITAlSTRATEGIES RESOLVETO SAVE LIVES An initiative of Vital Strategies STAYCONNECTED www.resolvetosavelives.org facebook twitter NIH-000781 From: To: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:49:23 +0000 Mark Feinberg Subject: RE:Thanks so much Date: Mark: Thanks for the note. Much appreciated. Bet, Tony ----- Original Message- ---From: Mark Feinberg (b) (6)> Date: Sunday . March 8. 2020 9:48 PM______ To: Fauci , Anthony (NTH/NIA ID) [E] ______ Subject: Tha nks so much ------ ~= ~= _> Cb _<_. Dear Tony, J hope you are doing well despite your extraordinar ily busy schedule address ing the COVID-19 outbreak. J just wanted to se nd you a note to ofter sincere thanks and deep admiration tbr you r tremendous efforts 10 provide the public with clear, insightful and accurate iufonn ation about this very ser ious public health threat and for your great leadership in helping to guide efforts to respond to it in the most effecti ve and scientifically grounded way . Our nation is so fortunate to have your full and expert engagement in this response. I can only ima gine how busy you are and you need not worry about responding to this note. However, l did want to share one voice of appreciation and thanks. Very best , Mark NIH-000782 Fauci, Anthony (NIH/N IAID) [El Mo n, 9 Mar 2020 01:37:26 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Countering COVID-19 From: Date: To: Subject: From: Clayton Conger Se nt : Sunday, Marc h 8, 2020 9 :36 PM To: Fa uci, Ant hony {NIH/NIAID) [E] Subject: Coun t ering COVID-19 (b)( 6)> ------~~ --------- = (b)(6) > Dr. An thony Fau ci Director of the National Institute of Allergy and Infectious D iseases Dear Dr. Fauci: It occurred to me that if viruses contain an iron atom , perhaps a form of magnetic treatment might stop or reduce the severity of the COVID-19 virus , so I investigated and found thatviruses have one atom of iron. My sugges tion is that experimentation on victims of the v ims be conducted, perhap s by inserting a tiny magnet into their lungs to see if it might gather up the vu.uses circulating in the victim . Perhaps externa l application of magnetism would work as well, J'm sw-e yom scientists will have even better approaches to so lv ing this problem. I'm a probl em so lver, hav ing pub lished a boo k that solves many of the Earth's problems: "Thinking Outsid e The Oven -- Concomitan t Concepts and Synergi stic Solu tions for the 21st Century" (availabl e at Barn es & Noble and Amazon ). I'm working on a sequel and if you find my idea useful I'll includ e a chapter on it. Very respectfully, Ned Conger (b)(6) C.N. Con er (b)(6) NIH-000783 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:33:55 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Record a short interview with me for a UPenn course? Sorry no. From: Scheyder, Elizabeth C Se nt: Sunday, March 8, 2020 6:03 PM ---------- To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b)'""' (= 6)> Subject: Record a short interview with me for a UPenn course? Dear Dr. Fauci, I am emba rrassed to admit that I was not familiar with your name when I read the story about you in today's NY Times, but I was most impressed by the statement in the first sentence that you are "widely respected for [your] ability to explain science without ta lking down to [your) audience" . I'm putting together the first offering of CLCH300 : Communicating Science, as part of the University of Pennsylvania's new online Certificate in Climate Change. {https :ij lpsonline.sas.upenn .ed u/academ ics/certificates/climate -change) A brief recorded conversation wi t h you about your strategies for communicating without being patronizing would be most enlightening for my students . The students in this course w ill be coming from a wide variety of backgrounds, and potentially from all over the globe. I think they wou ld love to hear from a scientist who is so good at communicating his field of study to diffe rent audiences. And let's face it, as soon as you say "NIH" as COVI0-19 swirls around the globe, their ears will certainly perk up! I think the students would find our interview very engaging and informative . The first run of the course will be from May 26 to July 20, 2020, but we can record the interview (on line) any time, since I know you are already over-extended right now . I think 15 minutes would be plenty, and I would be happy to send you questions that I plan to use to guide the conversat ion in advance. If a synchronous conversation is impossible given your schedule, I would be happy to just send you a couple of questions and ask you to use them to guide a 10-15 minute video that you record yourself . Please let me know what you think of this, and I will send you the syllabus when it's finalized , including where our interview would fit. Then I can begin the process of coordinat ing this with the Associate Director of our Online Learning Studio. Sincerely, Elizabeth Elizabeth C. Scheyder, Ph.D., P.E. SAS Computing Senior Instructional Technology Project Leader NIH-000784 & Lecturer in SAS Williams 441 B NIH-000785 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:32:52 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: FW: can you use a miRNA-seq assay to detect covid-19 in blood samples? Attachment s: GSE81852 MERSvs Mock control PCA p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarchical clustering heatmap p=2.le-8 q=7.79e-7 2 variables 8March2020.tif, GSE81852 MERSvs Mock control PCA p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif, GSE81852 MERSvs Mock control Hierarch ical clustering heatmap p=6.4e-7 q=4.2e-5 10 variables 8March2020.tif (b)(6) From: Hellmich, Helen Se nt: Sunday, March 8, 2020 5:52 PM To: Fauci, Anthony (NIH/NIAID) [E] -------c.c -------- .-.-= (b)(6)> Subject: can you use a mi RNA-seq assay to detect covid -19 in blood samples? Dr. Fauci, how are you sir? Long ago, in the early 90's, I was a post -doctoral fe llow in the Laboratory of Viral and Molecular Pathogenesis at NIH. I don't know if the same lab is still there. Now I work on brain injury and Alzheimer's but my interest in viruses and mechanisms of viral pathogenesis has not waned and the recent covid-19 outbreak prompted me to do a little investigation on my own. My studies of blood microRNA changes after TBI and AD suggest that principal component analysis of distinct changes in circulating miRNAs can identify the patient population. MicroRNA alterations can be measured by real-time PCRwhich I presume is the basis of the test that is developed for this disease but I am analyzing blood mi RNA-seq expression profiles and now it is possible to quickly sequence blood samples in a few hours and get accurate results. Blood gene expression in my studies was more var iable (lots of RNasesin blood) so I found that microRNAs are much more stable in blood and serum samples. I attach an example of a PCA/hierarchical clustering heatmap analysis of a GEO dataset for MERs-coV from 2016 https ://www .ncbi.n lm.nih.gov/geo/query/acc.cgi?acc=GSE8l852 I performed the PCA and heatmap analyses at two differen t stringencies and you can see that the patients can be unequivocably distinguished from the controls at very significant p and FDRvalues. Just a thought but many clinical centers , hospitals, academic institutions can quickly perfo rm transcriptome-wide sequencing. Blood RNA can be isolated in 1-2 hrs, sequencing libraries made in a few hres and one mi RNA sequencing run can handle up to 48 samples and the data can be quickly analyzed. Just my two cents on how NIH could accelerate the analysis of new blood samples for this new strain of coronanvirus . You could mob ilize hundreds of sequencing centers to help in the analysis. Regards NIH-000786 Helen Hellmich, PhD Associate Professor Department of Anesthesiology University of Texas Medical Branch (b)(6) NIH-000787 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:32:20 +0000 Erik Blutinger RE:Fighting the fight Thanks, Erik. From: Erik Blutinger Date: Sunday, March 8, 2020 7:02 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subje ct: Fighting the fight (b)(6) ------~~ -------- (b)(6)> Tony, It's been so inspiring seeing you fight tirelessly against COVID-19, sticking to the facts and stepping up to explain on a daily basis. If there's anything I can do to help from the world of emergency medicine beyond pat ient care, please let me know . Whether that means taking on a new project or pushing my specialty organization, the American College of Emergency Physicians (ACEP).I sit on their board and keep look ing for ideas to help fight this pandemic . Best wishes, Erik Erik J. Blutinger, MD, MSc Department of Emergency Medicine Mount Sinai Queens Hospital (c (b) (6) NIH-000788 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01:30:35 +0000 Cassetti, Cr istina (NIH/NIAID) [E] FW: COVID- 19 model From: William Schiesser (b)( Date: Sunday, March 8, 2020 6:53 PM ------- .----..-.= To: Fauci, Anthony (NIH/NIAID) [E) _:.:...__...:...::....:.!~~------Cc: William Schiesser (b)( > (b)(6) Subject: COVI0-19 model Hello Dr. Fauci, May I bring to your attention a prototype computer -based m athematical model for C0V ID-19 dynamics . I will be glad to send some deta ils if you t hink they would be of interest . Thank you for your consideration of this query. W . E. Schiesser, PhD, ScD htt p:// ww w .lehigh.edu/~wes1/id cove r 2.pdf NIH-00078 9 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 9 Mar 2020 01:27:36 +0000 (b)(6) To: Subject: RE:Californ ia DMV Coronavirus exposure danger I recommend that you keep trying to work with Governor Newsom's office since this is vey specific for the state of California. From: Date: Sunday, Marc h 8, 2020 8:12 PM To: Fauci, Anthony (NIH/NIAID) [E] -----Cc; Conrad, Patricia (NIH/NIAID) (b)(6)> --=(b=)(=6) [E] (b)(6) Subject: Californ ia DMV Coronavir us exposure danger Dear Dr. Fauci, I am writing to alert you to what I believe is a serious coronavirus health threat in California that is being posed by the California Department of Motor Vehicles . It has long been the policy of the California OMV that all drivers OVER 70 YEARS OLD must renew their drivers licenses IN PERSON at DMV offices. DMV offices are notorious for being extremely crowded and requiring long wait times where people are breathing on each other touching each other and undisinfected surfaces and touch screens for hours. As far as I am aware DMV offices are never sanitized so germs from thousands of people can remain there for weeks on end. This is obviously a dangerous environment for anyone in the current worldwide coronavirus emergancy yet nobody in the news media is reporting on it or even seems aware of the danger. In light of your recent statement warning people over to 60 to avoid crowds this California OMV policy seems to be incredib ly irresponsi ble and even life threatening but nobody is doing anything about it. (b)(6) "" N.,... e_w_s_o_m__________ __ . Only one day earlier on March 4 California Governor Gavin declared a State of Emergency in California to prevent the spread of coronav irus. I find this situation to be utterly absurd since Newsom is allowing California citizens to be exposed to exactly the kind of coronavirus danger he claims to be preventing and apparently does not even know that the DMV is totally contradicting his emergency declaration , the CDC recommendations, the California State Health Departmen t, the Los Ange les County Health Department, and the Pasadena City Health Departmen t. (b)(6) I am concerned that nobody seems to see the obvious public health threat. None of the relevant public health agencies have any information about this NIH-000790 on their websites and the Californ ia DMV website makes NO MENTION WHATSOEVER of Coronavirus as a health threat in there overcrowded offices. I would sincerely like to know what you make of this dangerous DMV policy. I also want to tell you that the Californai OMV is currently advertis ing on the radio asking even more people to crowd OMV offices in order to get the REAL ID license. REAL ID further exacerbates the danger by draw ing in more than NINE MILLION Californians to leave their germs in OMV offices over 1he next few months at the exact time we are in the midst of the greatest health emergency of this century and 1he most important recommendation is to AVOID CROWDS and stay at least six feet away from other people. Try staying six feet away from anyone in a crowded OMV office where hundreds of people are stuffed in like sardines. Obviously a rational policy would be to suspend the requirement for drivers over 70 to renew in person and simply let them renew by mail until the coronavirus emergency is over . The same should be done for REAL ID. A total suspension to protect public health in a crisis is the only sane thing to do. If I were the Director of the California OMV I would close all offices immediately and disinfect every inch of them, and not reopen until the coronavirus emergency is over. I would require that all OMV business should be done by mail or internet until the coronavirus threat is over . Please tell me what you think about all this and I will forward your response to local Pasadena officials since state level officia ls are almost impossible to contact even in an emergency when they most need to get this kind of information from the public but apparently do not want to know about bad news. I greatly appreciate your voice of reason in these scary times. I wish the officials of the State of California were as reasonable but they are apparently oblivious to a serious and unnecessary danger being created by one of their own state agencies. Sincerely Robert Maine (b)(6) NIH-000791 Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 01:24:37 +0000 Cassetti, Cristina (NIH/NIAID) [E] From: Date: To: Subject: FW: URGENT: (b)(4) ----------------------- (b)(4) (b)(4) Att achm ents: Please handle. From: Michael Matin Date: Sunday, March 8, 2020 8:01 PM To: Fauci, Anthony {NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: URGENT: 1mp ortan ce: High --------------------------- (b) (4} Dear Dr. Fauci: (b)(4l Please contact us at your earl iest convenience so that we may provide you with further data and information concerning this treatment. Best, Michael M . Mat in Chairman & CEO HDL Therapeutics, Inc. 60HDL Theapeu t icsl 21st Street , Suite 300 Vero Beach, FL 32960 (b)(6) From: (b)(4) -------------------6, 2020 6:18 Dat e: Friday, March at PM (b)(4) To: ===============~------c (b "")--=(4) (b)(4 Dear ---------- (b)(4):: NIH-000792 (b) (4) NIH-000793 (b)(4l NIH-000794 (b)(4l NIH-000795 (b)(4l NIH-000796 (b) (4) NIH-000797 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Mon, 9 Mar 2020 01:23:24 +0000 Krasne, Robert RE: Thank you!!! Bob: Many thanks for your note. Best, Tony From: Krasne, Robert Se nt : Sunday , March 8, 2020 7:59 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you!!! ------ ..-.-,= (b)(6J> Tony, Thank you for the science-based sani ty you are bringing to the COVID - 19 challenges. I follow your public comments with great interest (and publish them in our newspapers here in Pennsy lvania) and find solace that you are leading the efforts to address this extraordinary health care challenge. I cannot imagine the challenges you are facing, from disinformation to pure exhaustion, not to mention the sc ientific challenges that this virus brings. However , if anyone is capab le of wre stling these challenges to the ground, it is you. You have my profound appreciation and admiration. Best wishes to you, ---Cb)(6) and your family. Bob Rob ert M Krasne I Chief Executive Officer STE INMAN COM MUNI CATI ONS .,,..,.,.,._..,.Cb .,.,.. ~_(6) -!.. I SteinmanCommunications.com 8 West King St, Lancaster, PA 17603 NIH-000798 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 01: 19:21 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronav iru s Tre atment Question To: Subject: Please handle. From: Barb E Se nt: Sunday, March 8, 2020 7:26 PM ------------ (b)( 6) To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: Coronavirus Treatment Question 3-8-2020 Dr. Ant hony S. Fauci; I have attached an article I read on line abo ut a doctor in Taiwan treating patients w ith Coronavirus, with a combina t ion of ant i-viral drugs. Since the treatment helped the patients, I was won dering why they are not t reating patients in the United States with those drugs . Thank you. Sincerely, Barbara Eagan https ://www.yah oo.com/news /cockta il-flu-hiv-drugs -appears - 124753996 .html By Parm Wongcba- um Reuters•Februa ry 2, 2020 Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai doctors Reuters •February 2, 2020 NIH-000799 By Panu W ongcha-um BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new corona virus with combinat ion of medications for flu and HIV , with initial results showing vast impro vement 48 hours after applying the treattnent, they said on Sunday. The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year -old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days. The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltami vir in large doses. "This is not the cure, but the patient' s condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Krian gska Atipornwanich , a lung specialist at Rajavithi, told reporters. "The outlook is good but we still have to do more study to determine that this can be a standard treatment." Chinese health officials have already been administering the HIV and flu drugs to fight the corona virus. The use of the three together in a cocktail seemed to improve the treatment, the Thai doctors said. Another doctor said that a similar approach in two other patients resulted in one displaying some allergic reaction but the other showed improvement. "We have been following internat ional practices , but the doctor increased the dosage of one of the drugs ," said Somsak Akkslim , director-genera l of the Medical Services Department, referring to the flu medicine Oseltamivir . Thailand has recorded 19 cases of corona virus. Of the Thai patients , eight have recovered and gone home while 11 are still under treatment in hospitals . NIH-000800 Somsak said the health ministry will meet on Monday to discuss the successful treatment in the case of the 70-year-old but said it is still too soon to say that this approach can be applied to all cases. Initially we will apply this approach only to severe cases," he said. (Reporting by Panu W ongcha-um; Editing by Peter Graff) NIH-000801 Sent from Mai l for Windows 10 • Virus-free . www .avast.com NIH-000802 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Mon, 9 Mar 2020 00:45:58 +0000 Collins , Francis (NIH/OD) [E];Erbelding , Emily (NIH/NIAID) [E];Cassetti, Crist ina To: (NIH/NIAID) [E] Cc: Austin, Christophe r (NIH/NCATS) [E];Tabak, Lawrence (NIH/OD) (E];Conrad, Patricia (NIH/NIAID) [E] (bH 1 ·Marston , Hilary (NIH/NIAID) [E] Subject: RE:ACE2 Em ily/Cristina: Please contact Chris Austin and see if there is anything that we can do to he lp/coordinate with them. Thanks, Tony -------- From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, Ma rch 8, 2020 2:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ; Tabak, Lawrence (NIH/OD) [E] Subject: FW: ACE2 Hi Tony, team help? Best, Francis From: Austin, Christopher (NIH/NCATS) [E] Date: Sunday, March 8, 2020 1:51 PM To: Collins , Francis (NIH/OD) [E) ----- -------- (b) ~ > -= (b"'"" )( =6J> Subject: RE:ACE2 Hi Francis, Very interesting paper . Larry likely let you know about the enclosed exchange, but enclosed if not. (b)(5 NIH-000803 Chris From: Collins, Francis (NIH/OD) [E]______ Date: Saturday, March 7, 2020 11:07 PM To: Austin , Christopher (NIH/NCATS) [E]_______ Subject: RE:ACE2 Cb H_6>> _ ------~~ Cb _H_6) Structure of the coronav irus spike protein and ACE2 interaction From: Collins, Francis (NIH/OD) [E] Sen t: Saturday, March 7, 2020 10:58 PM To: Austin, Christopher (NIH/NCATS) [E]--------=Subject: ACE2 Yo Chris, - Francis NIH-000804 (b) ,.,(=6) is j ust out... From: Date: To: Cc: Subject: Greg: Thanks for this. Fauci, Anthony (NIH/NIAIO) [E) Mon , 9 Mar 2020 00:37:42 +0000 Greg Simon Erbeldi ng, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE:TXA127 for COVID-19 pneumonia --CONFIDENTIAL I will bring it to our group. I hope that all is well with you. Warm regards, Tony From: Greg Simon (b) ( > Se nt : Friday, March 6, 2020 7:22 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: TXA127 for COVID-19 pne umonia --CONFIDENTIAL here is the paper i ment ioned from a friend of mine fo r yo ur consideration. Thank you for all you'r e doing Greg ---------- Forwar ded message --------From: Rick Franklin (b)(6)> Dat e : Mon, Mar 2, 2020 at 5:46 PM Subject: TXA127 for COVID-19 pneumonia- -CONFIDENTIAL To: Greg Simon (b)(6)> Here's the paper. Let me know what you think . Best, Rick Greg Simon (b)(6) NIH-000805 From: Fauci,Anthony (NIH/NIAIO) [E) Date: To: Sun, 8 Mar 2020 23:55:07 +0000 Redd, Stephen (CDC/DDPHSIS/OD);Birx, Deborah L ( (b)(6)J);Grigsby, Garrett (HHS/0S/OGA);Kadlec, Robert (OS/ASPR/IO);Redfield, Robert R. (CDC/OD) Cc: Marston, Hilary (N IH/NIAID) [E] (b) (6) ;Eisinger, Robert {NIH/NIAID) [E]; Lerner, Andrea {NIH/NIAID ) [ E] Subject: FW: - Attachments: ----------------------~ = (b)(5) SSRN-id3549276.pdf Team: (b) (5) Thanks, Tony Paper attac hed. Dalton, Craig and Corbett, Stephen and Katelaris, Anthea, Pre-Emptive Low Cost Social Distancing and Enhanced Hygiene Implemented before Local COVID-19 Tran smission Could Decrease the Number and Severity of Cases. (March 5, 2020). Avai lable at SSRN: https ://ssrn .com/abst ract=3549276 or http ://dx.do i.org/10 .2139/ssrn .3549276 NIH-000806 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 22:56 :20 +0000 To: Cassetti, Cristina (NIH/NIAID) [El FW: For Novel Coronavirus of Ant iviral Treatmen t. Subject: FYI ________ ________ -------=-:--:= (b)__, (6)> From: IPJ::J~lli-1Date: Sunday, March 8, 2020 9:58 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: For Novel Coronavirus of Antiviral Treatment. _, (b)(6) Dear Director of NIAID, Anthony S. Fauci MD . : Potential inhibitors aga inst papain-like protease of novel coronav irus (SARS-CoV-2) from FDA approved drugs Version 2 Preprint revised on 20.02.2020, 00:05 and posted on 20.02.2020, 16:51 by Rimanshee Arya Amit Das Vishal Prashar Mukesh Kumar The cases of 2019 novel coronavirus (SARS-CoV-2) infection have been continuously increasing ever since its outbreak in China last December. Currently, there are no approved drugs to treat the infection . In this scenar io , there is a need to utilize the existing repertoire of FDA approved drugs to treat the disease. The rational selection of these drugs could be made by testing their ability to inhibit any SARS-CoV-2 proteins essential for viral life-cycle . We chose one such crucia l viral protein, the papain-like protease (Plpro), to screen the FDA approved drugs in silico. The homology model of the protease was built based on the SARS-coronavirus Plpro structure, and the drugs were docked in S3/S4 pockets of the active site of the enzyme. In our docking studies, sixteen FDA approved drugs , including chloroqu ine ard formoterol, was found to bind the target enzyme with significant affinity and good geometry, suggesting their potential to be utilized against the virus. FUNDING Department of Atomic Energy, Government of India Dear Dr . Fauci : NIH-000807 We are an individual researcher from Taiwan Biochemical Papain, my name is Terry Wang. Without funding support , (b)(4 (b) (4) I am willing to participate in the process in the United States. @@@There are many ways to perform the trea t ment ! Sincerely, Terry Wang in Taiwan . Please contact me : Email: (b) (6) Address: (b)(6) Cell phones: Line ID (b)(6) (b)(6) NIH-000808 Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 18:55:46 +0000 Gregg Gonsalves RE:We Are Desperate for Advice From: Date: To: Subject: Gregg: Understood . I appreciate your note . I will keep pushing . Best regards, Tony -----------------.~ From: Gregg Gonsalves (b)(6) Se nt: Sunday, March 8, 2020 2:54 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: We Are Desperate for Advice -------- (b)(6J> Tony, that part of the message was not directed at you . Peter Staley and I have seen you in action on TV and I've forced (b)( to watch you talking about social distancing, since she says the President says she has nothing to worry about. Bob Redfield and Secretary Azar haven' t been as forth right as you have. The main thing that concerns many people I know : the roll-out of testing , surveillance has been botched and we're likely to have cases of COVID in our communities already w ithout knowing it . Meanwhile some corporations, some universities, some other institutions have started to put social distancing into place, with a few municipa lities doing the same, but there is no real guidance from CDCon when to act for most of us. There are plenty of instructions about getting prepared, but all seem to point towards waiting until there is an outbreak in one's community to do anything substantial, which seems if you'll excuse my language, ass-backwards, as one you see multiple cases, you're likely to already have widespread community transmission . I think this piece by Bill Hanage at Harvard explains where a lot of us are right now : https ://www.washingtonpost .com/outlook/co ronavirus-test ing-united -states/2020/03/0S/a6ced5aa Sf0f- llea-9055 -5fal2981bbbf story. htm l Stay well, we need you more than ever (and I mean that from the bott om of my heart). Most of the career civil servants on the email were copied not to chastise, it's the political appointees that most think got us into this mess. g From: Anthony Fauci (b)(6) Date: Sunday, March 8, 2020 at 1:50 PM ------------ To: Gregg Gonsalves Subject: RE: We Are Desperate for Advice (b)( > Gregg: I am surprised that you included me in your note. I genuflect to no one but science and a lways, always speak my m ind when it comes to pub lic hea lth. I have cons istent ly corrected missta t ements by others and will con t inue to do so. I am including t wo links from Sunday NIH-0008 12 Shows today where I am extremely explicit and forceful. I would be happy to chat with you about this. https ://ap p.crit icalment ion.com/app/#/c lip/publ ic/2beb07d0-f72d -45b9-9ed660754bd93fa7?show sent iment=false ht tps://app .cri ti calmention .com/app/#/c lip/publ ic/183207e9 -e6e1 -4164 -ble5 - 53e0dddbc363?show sentiment=fa lse Best regards, Tony ----------------~~ From: Gregg Gonsalves Date: Sunday, March 8, 2020 11:17 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6)> (b)(6)>; JeffTrammell >; Redfield, Robert R. (CDC/OD) (b)(6J> ; Collins, Francis (NIH/OD) [El (b)(6J>; Lane, Cliff (NIH/NIAID) [E} (b)(6J>; Schuchat, Anne MD (CDC/OD) (b)(6 b; Messonnier, Nancy (CDC/DDID/NCIRD/OD) (b)(6) Birx, (b)(6)>; Azar, Alex (OS/IOS) (b)(6); Redfield, Robert Deborah L (b)(6)>; Harrison, Brian (HHS/IOS) CbH6J> Subject: We Are Desperate for Advice (b)(6) ":'--:---~--=-::======-~~--======~~- ---- == ___ ___,!=====~~ ----------- Dear Tony, Bob and Deb et al, The AIDS experts among you know me well. We've been first adversaries then colleagues for over 30 years. They also know I can't keep my mouth shut, which is a virtue and a failing, depending on the context. Now : There are thousands of people waiting for advice from our federal government on broader social distancing measures in light of the fact that our failure in early testing and surveillance means the coronavirus is likely already spreading in our communities . If you thought the ire of AIDS activists 30 years ago was tough, the anger now spreading among researchers, scientists, clinicians and activistsis going to be a conflagration. All we see is genuflection in word and deed fr om most of you to a White House that wants thi s all to magically go away. Yes, I know you're all doing your best and behind the scenes our federal government is hard at work . For those I know, I don't doubt your commitment to publ ic service. But time is running out. We need vocally, unequ ivocal leadership now, that offers real guidance to communities about what to do, what might happen next. Your own legacies will be defined by this moment, what you do and what you don't, what you shy away from saying because you fear for your jobs or your short-term fortunes in the eyes of the President. The status quo is untenable. It's going to get people killed by this virus . Gregg NIH-0008 13 Gregg Gonsalves PhD Assistant Professor, Epidemiology of Microbial Diseases Yale School of Public Health Associate Professor (Adjunct) and Research Scholar Yale Law School Co-Director, Yale Global Health Justice Partnership Co-Chair, Global Health Studies Faculty Committee, Yale College Affiliated Faculty, Add iction Medicine Affiliated Faculty, Jackson Institute for Global Affa irs (b)(6) NIH-0008 14 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 17:06 :22 +0000 Conley, Sean P. CDR USN WHMO/WHMU Munster , Vincent (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) (b)(6);Lerner, Andrea (NIH/N IAI D) [El;Eisinger, Robert (NIH/NIAID) [El;Birx, Deborah L (b)(6)) To: Cc: [El -----~~ Subject: Attachments : FW: Stability data - spoke to Vincent. 2020 -03-03 Manuscript Stability_MASTER .docx Sean: As per our recent conversation Dr. Vincent Munster , here is a paper that is under review at the NEJM . It is from who works in my institut e. It confirms what we surmised that after almost two weeks, the chances of viable virus being present in the facility is extremely low based on his stud ies reported in this paper . Figure 18 in the paper is of particular relevance regarding our discussion of surfaces. Best regards, Tony (b)(6) From: Marston, Hilary (NIH/NIAID) [El Date: Saturday, March 7, 2020 3:40 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) > -------::-::-:-= (b)(6)>; -------- Lane, Cliff (NIH/N IAI D) [El --------- Cc: Lerner, Andrea (NIH/NIAID) [El Subject: Stability data - spoke to Vincent. (b)(6) Talked to Vincent. Attaching his manuscript, unde r review with NEJM. Vincent is available at - (b)(6) if you need him. How the experiments were done: Aerosol -A solution of live virus was made and aerosolized in a rotating drum (kee pi ng it in aerosol form) ; at various time point s, air was removed and amount of virus measured (using end-poin t titration on Vero cells). Surface - A base solutions of live virus was made and placed on specific surfaces (plastic, etc) and at various time points, coating was taken away and virus contained was titrated. Note t hat surface experiments with proteinaceous material (e.g., respiratory secretions) are underway, as are variations in relative humidity and temperature. How do you interpret aerosol data? Decay in aerosols occurs over three hours, so if the virus is aeros ol ized (via aerosol-generat ing procedures or cough), the moment it drops below a certain threshold, it would be hard to get an infect ious dose/infection. Of course we do not actually know the infectious dose, which limits our abil ity to give firm guidance based on this data. NIH-000815 How do you interpret the surface stability data? Copper seems to have some virucidal effect, as is seen with other viruses. Plastic and stainless steel don't have much of an effect on the virus itself, and the virus persists for some time. As for cardboard, difficult to interpret because the surface absorbs a good deal, but there is some immediate decay. Should we be concerned about packages based on your data? This is of far lower concern than droplet and other fomite transm ission. Typical shipping wil l allow ample time for viral decay, and the card board itself seems to have some direct effect on the virus (either through absorption or other effect) . For example, in the experiment, Vincent applied lOeS viral particles/ml and it drops 2 logs to 10e3 immediate ly, ind icating that either due to absorption or direct effect on the virus . Of course, if a mail carrier coughs on a package and then someone touches it directly after, there may be a risk. The typical shipping situation is likely not a concern. Why are SARS-CoV-2 vs. SARS-CoV-1 different? For the cardboard data in particular, there is a difference seen between SARS-CoV-2and 1, which is likely due to error/variation in surface. NIH-000816 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 14:30 :13 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: A Coronavirus Deterrent? From: Ron Jacobs Date: Sunday, March 8, 2020 10:13 AM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: A Coronavirus Deterrent? (b)(6)> ------~~ -------- (b)(6) Would the use of a facial steam inhalator cause nonviability of the virus in someone who had contracted the virus? Would spending time in a steam room have a similar effect? NIH-000817 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 14:29:44 +0000 To: CbH6l;'Birx,Deborah L';Redfield, Robert R. (CDC/OD);Kadlec, Robert (OS/ASPR/IO);Redd, Stephen (CDC/DDPHS IS/OD) Subject: FW: Hazardous use of Remdesivir in CoV-19 Attachments: COVIO19linee guida trattamento 0lMAR.pdf .pdf .pdf There may be nothing to this, but we shou ld at least be aware. (b) ~ > From: rosario leopard i Date: Sunday, March 8, 2020 9 :04 AM To: Fauci, Anthony (NIH/ NIAID) [E]-----~~ Subject: Hazardous use of Remdesivir in CoV-19 -------- ------- (b)(6)> Dear Dr Fauci, I am copying below a let t er I just sent to the ed itors of Lancet and NEJM t hat I th ink you should also read. It's informal as it is not meant for publication but ju st as a concern. Since I no longe r work as a virologist, I am forma lly out of the fie ld. I am however active as chief psychiatrist in Stockholm, Sweden. If you have doubts as to my expertise as a virologist or a physician, Dr Bernard Roizman at U of C knows me very well, as M ar kus Heili g does here in Sweden . "I have noticed a striking difference in mortality by Co V-19 in different countries. China and Italy have a morta lity that 's at least 6-fold higher than that in South Kor ea. So far Germany and Scandinavia , totalling over 1300 cases, have not rep orted a single death. That' s over a 35-40 fold difference. Loo kin g at the data more closely, I have found that China and Ital y have been using the antivira l Remdesivir (Gilead Sciences) extensive ly on many patients in intensive care , ju stifie d as "compassionate use" . In the epidemic areas of Italy this drug is now part of treatment guidelines for hospitalised patients , used on every single patient in "criti cal conditi on". (see attachment). The "rationale" is simp ly that the first two cases treated at the SpaHan.zan.iHospital in Rome rec eived this dn1g, and ...we ll, actuall y surv ived. NIH-000818 Remd esivir has never passed a Phase 3 trial, but has already made big head lines in major international newspaper s. Neither South Korea nor Germany or Scandinavian countries have yet used this drug. I unde rstand that this is a (relatively) long shot, but given the number oflive s at stake, I would recommend that a carefully scrutiny by the scientific community on the use of this drug is warranted. I have no conflict of interest. Thank you for your attention". Sincerely , Rosario Leopardi , MD, PhD ____ Forensic Psychiatry Care Clinic Cb)C6) , Sweden cell : (b)(6) Sent from Outlook NIH-000819 (b)(6) From: Date: Sun, 8 Mar 2020 09:59 :21 -0400 To: Conrad, Patricia (N IH/ NIAID) [E);Folkor s, Greg (NIH/NIAID) [E);Mar ston , Hilary (NIH/NIAID) [E];Lerner , And rea (NIH/ NIAID) [E]; t isinger , Robert(N JH/NIAID) [E];Barasch, Kimberly (NIH/N IAID) [CJ Subject: Fwd: BIO Coronavirus Collaboration Initiative March 12th Summit - POSTPONED Begin forwa rded message : From: Phylli s Arthur Date: M arch 8, 2020 at 9:51 :46 AM EDT To: Phyllis Arthur Cc: Jenni fe r Alton , Ellen Carlin (bH6) >, Amy Walker , Grego1yFrank ---------< gfrank@bio.org>, Hannah Dorsey Subject: BIO Coro navirus Collaboration Initiative March 12th Summit - POSTPONED Dear Colleagues, BIO is heartened that so many of you have expressed interest in join ing us for the BIO Coronavirus Collaboration Init iative Summit planned for March 12, 2020. Given the evo lving circumstances surrounding the COVID-19 outbreak, and afte r discussions with our Board leadership, we have decided to postpone the BIO Summit so that we can make adequate arrangements to hold t he meeting virtual ly. We made this decis ion out of an abundance of caution , so as to avoid placing anyone at unnecessary risk of exposure whi le we work together to improve our nation's ability to respond to this outbreak. We will re -schedu le this virtua l meeting within the next two weeks using a digital techno logy that can allow for robust discussion among the participants. In the inter im, we plan to send out a short questionnaire on Monday to all company participants requesting information on your product, technology or serv ice, which we plan to compile in a digital "book" and share with all participants in advance of the meeting . We believe this approach wi ll help to make the meet ing more efficient, allowing us to quickly shift to discussions of the NIH-000820 most impo rtan t shared challenges and potential opportunities that exist between industry members, government leaders and nongovernment partners. Please feel free to reach out to me with any questions. We will move qu ickly to establ ish a new date for this meeting and appreciate your flexibility in t h is regard. We look forward to talk ing with many of you then . Thanks again for your commitmen t to enhancing the health and safety of people facing this outbreak around the globe. Sincerely, Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T: 202 -962 -6664 C (b) (6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio .org Convention Phyllis A Arthur Vice President, Infectious Diseases and Diagnostics Policy Biotechnology Innovat ion Organization (BIO) 1201 Maryland Ave SW, Suite 900 Washington , D.C. 20024 T : 202 -962 -6664 C: (b)(6) parthur@bio.org Join us at the 2020 BIO International June 8-11, 2020 in San Diego, CA www.convention.bio.org NIH-00082 1 Convention From: (b)(6) Date: To: Subject: Sun, 8 Mar 2020 09:50:00 -0400 Cassetti, Cristina (NIH/NIAID) [E] Fwd: COVID19.ACElsand ARBs Please handle Begin forwarded message: From: Martin Engman Date: March 8, 2020 at 9:30:51 AM EDT To: "Fauci, Anthony (NIH/NIAID ) [E]" Subject: COVID19, ACEis (b)(6) ------~~ --------and ARBs (b)(6J: Is there any evidence to suggest that patients already on treatment with angiotensin receptor blockers have a better or worse COVID-19 outcome than patients not on these medications?Similar question for initiating ARB treatment once COVID-19 has been diagnosed. And s imilar questions for ACE inhibitor s. Thank you. NIH-000822 From: Date: (b)(6) Sun, 8 Mar 2020 09:23:28 -0400 To: Kristian G. Andersen Cc: Jeremy Farrar;Collins, Francis (NIH/OD) [E];Robert Garry;Edward Holmes;Andrew Rambaut;lan Lipkin;Chris Emery Subject: Re: SARS-CoV-2article to be published in Nature Medicine Kris tian: Than.ks for your note. Nice job on the paper. Tony On Mar 6, 2020 , at 4:23 PM , Kristian G. Andersen --------- (b)(6) wrote: Dear Jeremy, Tony , and Francis , Thank you again for your advice and leadership as we have been working through the SARS-CoV-2 'origins' paper. We' re happy to say that the paper was just accepted by Nature Medicine and should be published shortly (not qui te sure when). To keep you in the loop, I just wanted to share the accepted version with you, as well as a draft press release. We're sti ll waiting for proofs, so please let me know if you have any comments , suggestions, or questions about the paper or the press release. Tony, thank you for your straight talk on CNN last nigh t - it's being noticed. Best , Kristian Kristian G. Andersen, PhD Associate Professor, Scripps Research Director oflnfectious Disease Genomics , Scr ipps Resea rch Translational Institute Dir ector , Center for V iral System s Biology The Scripps Research Institute 10550 North Torrey Pines Road, SGM-300A Depa1tment of Immunology and Microbial Science La Jolla, CA 92037 (b)(6) NIH-000823 NIH-000824 From: Date: (b)(6) Sun, 8 Mar 2020 09:04 :10 -0400 Lane, Cliff (NIH/ NIAID) [E] Re: COVID-19 Real Time, Sensitive Detection Breakthrough To: Subject: Please take care of this yourself Thanks On Mar 7, 2020, at 11:30 PM, Lane, Cliff (NIH/NIAID) [E] (b) (6) wrote: -------- They claim to have an improved diagnostic developed through DoD funding. It is a DNA platform that they claim to have adapted to COVID-19. They prov ide no data , o_Jl )y__ cJaims_________________________ ~ (b) (5) On Mar 7, 2020 , at 10:03 PM, Fauci, Anthony (NIH/NIAID) [E] (b) (6) wro te: Please read this and figure out what th e heck he is talking about and act accord ing to your jud gment. Only 498 emails to go tonig ht. From: (b)(6) Date: Saturday, March 7, 2020 4:09 PM To: Fauci, Anthony (NIH/NIAID) (E] (b)(6) Subject: COVID-19 Real Time, Sensitive Detection Breakthrough -----~~ Tony-It has been awhile since we have worked together since my time as the senior SES standing up DTRA (with the help of Josh Lederberg M.D. &Dave Franz DVM who you know), at Argonne/UofChicago establishing your NIAID RBL with Olaf Schneewind M.D., and as the OHS Director of Research reporting to SEC Michael Chertoff &U/S Jay Cohen (RADMret). Michae l &Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Executive Director &Chief Scientist. I know you have your hands very full with the NIH-000825 COVID-19 threat, so I wanted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged. Thanks to DARPA &OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system for human identification, the ANOE group has a breakthrough for detection of COVID-19 and to the future , other emerging threat viruses. As you may know the ANOE system for human identification (e.g. CT &OHS missions) is mature and now deployed operationally/tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in EI Paso to demonstrate its effective capabilities to determine family relationship in undocumented minors. Additionally ANOE is in use by law enforcement and by officials responding to mass casual ty events (CA 2018 Camp Fire disaster , 2019 Conception dive boat fire, and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provides 2 hour turnaround with no special training requirements as a stand-alone system for all the above users . Our wa rfighters and special operators are using the ANOE system now in field forward operations and it meets M IL specs &is the only system certified for data submission to the OoO AB IS/DIA DNA reposi tory and FBI CODIS data base. The (b) (4) executive summary and a more in-depth document for your teams review . Hope the above is helpful and I stand ready to provide any additional information . I have cc'd Jim Davis (ANOE Chief Federal Officer) . Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer &Founder , Richard Selden M.D. , Ph.D . Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker NIH-000826 Member-Homeland Security Experts Group , MITRE Global Strategy Officer -Defense &Homeland Security/Intelligence ANDE Corporation p: (b)(6) e: m: ------- (b)(6) >!:II.ii ANOE ' ~ Rap id DNA for a Safer World (b)(4l NIH-000827 (b)(6) From: Date: Sun, 8 Mar 2020 07:41 :41-0400 NIAID Public Inquiries Fwd: Ems Personnel & Ambulance Teams To: Subject: Sent from my iPhon e Begin forwarded message: From: "Nabial, Nasir M " (b)(6) Date: March 7, 2020 at 10:54:39 PM EST To: "Fauci, Anthony (NIH/NlAID) (E]" Subject: Ems Personnel &Ambulance Teams -------= -------- = (bH Dear Dr . Fauc i: Im a first responde r, and I believe an oral vaccine platform is the best delivery method for situations of national emergency like the coronav1rus. lf the vaccine is a tablet, we would be able to keep them on our ambulances and get medical authorization whenever the situation arises. First responders can then treat patients before doctors and nurses and also instead of having the patient make an appointment Or having them wa it in line for a shot , which can ultimately cause more spread . This me thod that will enable the EMS teams of the nation to combat outbreaks because you would allow EMT (Emergency Medical Technicians) and Paramedics to diffuse situations through our Ambulances. This w ill lead to more control and get a hold of the situations as fast as possible and lower the spread of the virus on our people. Thank you . NIH-000832 From: Date: (b)(6) Sun, 8 Mar 2020 07:40:53 -0400 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: from Dr Mike Meyer ( CEO- Sensible Biotherapeut ics) Finding the answer to halting replication of COVID-19 Pis respond Sent from my iPhone Begin forwarded message : From: Michael Meyer Cb) C Date: March 8, 2020 at 12:28:03 AM EST To: "Fauci , Anthony (NIH/NIA ID) [E]" CbH> , philip meyer CbH>, "Perkins, Miriam (NIH/NIAlD) [E]" ------~~ (b)(6) Subject: from Dr Mik e Meyer ( CEO - Sensible Biotherapeutics) Finding the answer to haltin g replication of COVID-19 DR ANTHONY FAUCI (b)(6) Dear Dr. Fauci , I am a Neuro logist and Nuclear Medicine Phys ician who has a passionate interest in developing antisense med ications to treat disease and have formed a drug discovery company here in Buffalo New York (SENS IBLE BIOTHERAPEUTICS , LLC). (b)(4) NIH-000833 (b) (4) I very much appreciate any advise you may be able to provide about this project Sincerely, Michael A. Meyer MD cell Cb)(6) NIH-000834 From: (b)(6) Date: Sun, 8 Mar 2020 07:39 :47 -0400 To: NIAID Public Inquiries Subject: Fwd: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of go ing to hospita l Sent from my iPhone Begin forwa rded message: From: rebecca hagenberg (b)(6) Date: March 8, 2020 at 3:06:34 AM EDT To: "Fauci , An thony (NIH/NlAI D ) [E]" (b)(6) Subject: Set up county hotline for people to contact if they think they have coronavirus or are sick instead of going to hospital -------~~ Dear Sir , I am sending this message to assist in an idea to help m inimi ze the impac t of Coronavirus. Instead of people going to the hospital or urgent care. Each county health depa rtment needs to have a direct number of a nationa l number that distributes information to local county governmen t health department. If you are sick and show or exhib it signs of the coronavirus you shou ld call the appropriate number , a technician wi ll come to yo ur home, draw lab specimen needed. Of course if someo ne is extremely ill they shou ld call 9 11 and adv ise 911 they are exhib iting signs of the virus. The re sho uld be special protocols in p lace for how to transport the patient into the hosp ital as well ( to limit exposure to everyone involved. This means finding alternat ive entrance at hospi tals for a suspected coronavirus patient. These patients shou ld be brought in by a least used locat ion of the hospital into a spec ial unit that has a barrier from the rest of the emergency department. Home lab work will keep someone from sitting in a waiting room for 3_ 5 hours. The county unit to conduct lab wo rk wi ll act in response much like calling 911 or the po lice. Eac h hospital needc; to set up an emergency entran ce for Coronavirus patient s only, and the unit must be sealed from the rem ainder of the unit. We begin having a coronavirus team that does not cross contaminate to any other unit on the emergency room floor. I am thinking of the best p lausible way to minin1ize outbreak . This helps . Rebecca Hagenbe rg (b)(6) NIH-000835 From: Date: Fauci,Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:34 :45 +0000 To: Michael Oldstone RE: item Subject: Thanks, M ichael. I appreciate your note. From: M ichae l Oldstone Date: Friday, M arc h 6, 2020 2:12 PM To: Fauci, Anthony {NIH/ NIAID) [E] -----~~ (b)(6) Subject: item Dear Tony A note to let you know how much over the years I have appreciated your active support of biolog ic research, public health and your directorship of NIAID . Impressive, intelligent, high integrity and management skills has placed you at the head of the curve. I reached this conclusion from personal observat ions of your work and style as wel l as having served as a consultant for NIAID and several other NIH Institutions, WHO, Pasteur and Karolinska . After nearly 50 years of continuous research from my original AI09484 grant studying viral pathogenesis[ acute and persistent infections] using the LCMV model, I decided to close my laboratory. I have had other generous NIH support as well especially for investigations of other negative strand viruses[ primarily measles and influenza, Lassa ,arenavirus receptor] , Ebola, cytokine storm and autoimmun ity. The AI09484 grant was credited by 300 peer reviewed papers, training of 61 postdoctoral fellows[ including Rafi Ahmed , Christine Biron , Persephone Borrow, Ray Welsh, Ian Lipkin , Dorian McGavern and other successes including the late Patrick Sissons who was the Reagent Professor of Medicine at Cambridge. Over 85% of these folk are in academic medicine/b iology at research institutes or universities. Good luck and smooth sailing with the current coronavirus pandemic. With your involvement this work is in good hands . Best wishes Michael NIH-000836 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:26:22 +0000 To: Cc: Liz Cheney Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Greg Folkers -------- (b ~ )~(6) = RE:Test Kits Subject: Sorry, Liz. In White House all day. Will try to call tomorrow. From: Liz Cheney CbH6)> Date: Friday, March 6, 2020 2:14 PM To: Fauci,Anthony (NIH/NIAID) [ E] -----~ (b).-.(= 6J> Cc: Barasch,Kimberly (NIH/NIAID) [C) CbH ; Conrad, Patricia (NIH/NIAID) [E) (b) ( '> Cb)( ; Haskins,Melinda (NIH/NIAID) [E) Subject: Re: Test Kits --------- --------- Dr. Fauci - Who can I speak w ith about the status of the test kits ? I am also concerned about reports from CDCthat there are six states, including Wyoming, with no certified lab in which to conduct tests. Thank you, Liz Cheney (b)(6) -------- On Tue, 25 Feb 2020 at 10 :28 PM, Fauci, Anthony (NIH/NIAID) [E) (b)(6J> wro te : Liz: Thank you for your note. I would have been very happy to provide remarks at the weekly meeting of the Republican Conference. However, I have a late afternoon 2nd panel Congressional Hearing with Secretary Azar followed by a meeting with the President in the Roosevelt Room of the White House, which over laps with the time frame of your meeting tomorrow. I would be most happy to do this at another time. If you could have your office contact my Special Assistant, Patty Conrad (copied here) , she will help arrange setting up something at a mutually convenient time. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone (b) (6) FAX : (301) 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive informa tion . It should not be used by anyone who is not the original intended NIH-000837 recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Liz Cheney (b) (6) Date: Tuesday, February 25, 2020 6:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: House GOPConference Mtg (b)(6) Dr. Fauci - I am the House Republican Conference Chair and we are holding our weekly mtg at S pm tomorrow in the Capitol. I wanted to see if you'd be available to provide remarks and an update on Coronavirus. It is by far the topic in which our members are most Interested, and you would be the best person to provide an update . I realize th is is short notice . If tomorrow doesn't work , let me know if we could arrange another time. My eelI is ------ (b)(6), ____ office is ._ (b)(6) _. Thank you, Liz Cheney NIH-000838 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 03:23 :05 +0000 Hilary Rosen RE:You! Hila ry: Thanks for your note. I would postpone it. The situation is very fluid. best, Tony From: Hilary Rosen Date: Saturday, March 7, 2020 9:01 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: You ! (b)(6) ------~~ -------- (b)(6) Tony, I am so proud of you . It is so comforting to see your face on TV explaini ng the world of coronavirus . know it is exhausting for you but it is so important . Your dedication my friend has always been so admirab le. Quick question, CDCisn' t giving much guidance on this. Our company has its annual retreat this week. About 80 people coming from NYCand LA meeting in a DC Hotel ballroom for two days with an additional 100 people from DC. SO approximately 180 in total. Would you postpone this if you were me? XO Hilary Hilary Rose n Vice Chair SKDKnickerbo cker 202.4 64 .69 69 w (b)(6) m 2019 Holmes Report Public Affair s Ag ency of the Year NIH-000839 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:06 :52 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) (6) FW: medi a request from spain an old journal ist friend , patricia mat ey Cannot do. No t ime From: Patricia Matey Corada Date: Saturday, M arch 7, 2020 3:31 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: media request from spain an old journalist friend, patricia matey -------=---c-c= Hi doctor Fauci, Can you remembe r me. I am a Patricia Matey, oldest journalist of health from spain. I work in the past in El MIU ndo, now I am a chief editor in El Confidencial, the first newspaper online in Spain. Can you give me little time for answer some questions . I want to do an article of the coronav irus, but the eyes of science, I read three days ago te article in New Yor Times by Gina Kolata, the best woman health journalist of the wo rld, I want to do an art icle without panic and false concept I send you some questions What is really the differen ce in this conoravirus and the past? Can one of the mute ate , change in one strain more aggressive in short time The fl u always affect a all t he count ries in same time . Why the new coronavirus only star enChina, Is because became from one animal,,, What are your opinio n for the really impact of this virus What are you opin ion for the press and the paper in this problem. What are you op inion for the evolut ion in the next month Best regard for all, but best regard for yourtime tC Patricia Matey Jefa de Alimente www.e lconfidencial.com Via de las Dos Castil/as, 33. Edificio 7. Planta 1- Oficinas E,F, G, H 28224 Pozue lo de Alarcon (Mad rid) (b)(6) NIH-000840 From: Date: Fauci, Ant hony (N!H/ NJAID) [E) Sun, 8 Ma r 2020 03:03:28 +0000 To: (b)(6) Cc: Subject: Conrad, Patricia (NIH/N it1t. lD } [ E] FW: COVID-19 Real Tim e, Sensiti ve Detect ion Breakth roug h (b) (4) CUsersstarnD eskto pSEW Bio, October 2019.docx, CUsersstarn Desktop ANDE BiosRFS CV 05 M arch 2020 .pdf Please read th is and fig u re out wha t t he heck he is tal king about and act according to your j udgm e nt. Only 4 98 em.::iils to go tonigh t . From: Date: Saturday, M arch 7, 2020 4:09 PM (b)( 6) To: Fauci, Anthony (NIH/N IAID) [ E] -------= (b,.,.. )(=6) ----------------- Subject: COVID-19 Real Time, Sensitive Detect ion Breakthrough Tony-It has been awhile since we have work ed together sin ce my time as the senior SES standing up OTRA (with the help of Josh Lederberg M.O. & Dave Franz DVM who you know), at Argonne /UofChicago establishing your NIAID RBL with Olaf Schneewind M.D ., and as the OHS Direc tor of Research reporting to SEC Michael Chertoff & U/S Jay Cohen (RADM-ret) . Michael & Jay brought me aboard when Jay was our Chief of Naval Research at ONR and I was ONR's Execu tive Director & Chief Scientist. I know you have your hands very full with the COVID-19 threat, so I wan ted to give you a heads up that a game changer for enhanced detection of COVID-19 has emerged . Thank s to DARPA & OHS S&T sponsorship in years past of ANOE developing a real time Rapid DNA microfluidics system fo r human identificat ion, the ANOE group has a breakthrough for detection of COVI0 -19 and to the future , other emerging threat viruses . As you may know the ANOE sys tem for huma n identification (e.g. CT & OHS missions) is mature and now deployed operationally /tactically by CENTCOM , DIA , the IC and used most recently by OHS in their recent test bed in El Paso to demonstrate its effective capabil ities to determine family relationship in undocumente d minors. Additionally ANO E is in use by law enfor cemen t and by officials responding to mass casualty events (CA 2018 Camp Fire disaster, 20 19 Con ception dive boat fire , and the very recent 2020 tragic helicopter crash) to ID the victims . The ANOE system now provid es 2 hour turnaround with no special training requirements as a stand-alone system for all the above users. Our warfighters and special operat ors are using the ANOE sys tem now in field forward operation s and it meets MIL specs & is the only system certified for data submission to the DoD ABIS/ DIA DNA repository and FBI CODIS dat a base. The Cb H4> NIH-00084 1 (b) (4) attac liecJ an executive summary and a more in-dep th document for your teams review. Hope the above is helpful and I stand ready to provide any additional information. I have cc'd Jim Davis (ANOE Chief Federal Officer). Additionally since it has been some time since we have worked together I have attached my bio and that of ANDE's Chief Scientific Officer & Founder, Richard Selden M.D. , Ph.D. Tony thanks for considering this in your very busy life now and I will look forward to seeing you again. Best regards-Starnes Dr. Starnes E. Walker Member -Homeland Security Experts Group , MITRE Global Strategy Officer-Defense & Homeland Security/Intelligence ANOE Corporation p: (b)( 6) m: '\71 ----~ ---______ (b)(6) w: www.ANDE.com e: /A ANO (b)( _. 6) ... E' 2 ~? Rapid DNA for a Safer World NIH-000842 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 03:00:50 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Corona Virus plann ing Please respond. From: K.A. Traul (b) (6) Date: Saturday, March 7, 2020 4:42 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Corona Virus planning ------------- == (b)(6) Dear Dr. Fauci; I am a toxicologist and have spent time, years ago, working in the arena of oncogenic virology as part of NCI programs. I am very concerned about what I see in the news media about the NIH approach to the COVID-19 pandemic (yes, pand emic) that has arrived in our country. There is much talk about development of a vaccine , however , I believe that this is a long-term strategy. You and I both know , from working as scientists, that the develop ment and trial of an antiviral vaccine is a months-long program, at best. I am surprised, even disappointed , that there seems to be no visible focus on the part of the NIH on the development of anti-viral treatments (drugs etc) . It is my professional opinion that anti-virals would take a shorter time to develop than vaccines, yet it appears that this may be a back burner focus of NIH . I realize that there are many political pressures on your office and I support your strong efforts to apply science to the resolution of this growing problem . Please do not give short shrift to th e potential of antiviral treatments in favor of the longer-term promise of a vaccine. Respectfully yours, Karl A. Traul K.A. Traul , Ph.D. K.A. Traul Pharmaceu tical Consulting (b)( 6) NIH-000846 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 02:59 :37 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview request I really do not have time for this. From: Kopelman, Hannah Date: Saturday, March 7, 2020 5:19 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> Cc: Ross Kopelman _________ Cb _>_C6) _ Subject: Interview request ------~~ Dear Dr. Fauci, My name is Dr. Kopelman. I am currently a resident at Boston Medical Center. I am reaching out because I would like to interview you on my podcast along w ith (b)(6)·, on our podcast called MedChatMonday wh ich reaches thousands of millenn ia ls a day. We want to discuss Coronavirus. I know you are very busy so any of your time would be appreciated. I want to discuss the implications of Coronavirus, symptoms, understanding of why it has become a global scare, what people should do to combat and lower their risks. Podcast will be done remotely through Skype. I hope to hear from you soon. Best regards, Dr. Hannah Kopelman and Dr. Ross Kopelman Hannah B. Kopelman This electron ic transmission may conta in information that is privileged, confidentia l and exempt from disclosure under applicable law. If you are not the intended recipient , please notify me immediate ly as use of this information is strictly prohibited. NIH-000847 From: Fauci, Anthony (NIH/NIAID) [E) Date: Sun, 8 Mar 2020 02:58:52 +0000 (b)(6) To: Cc: Marston, Hilary (NIH/NIAID) [E];Conrad , Patricia (NIH/NIAID) [E];Barasch, Kimberly (NIH/NIAID) [C] Subject: FW: One Step COVID-19 test kitS - IMMEDIATE AVAILABILITY Attachments: DoN SARS-CoVtests 200305.pdf, IFU One Step COVID-19 Test.pdf , 002.png, 0005.jpg , 0099.jpg, 9999.jpg, 0001.png What do you think of this. Do what you need to do. From: (b)( > Date: Saturday, March 7, 2020 6:26 PM To: vice.president@whitehouse.gov Cc: secretary@hhs.gov; Hahn, Stephen (FDA) (b)( ; Redfield , Robert R. (CDC/OD) (b)(6) ; Fauci, Anthony (N... IH - /7:N--IA--ID :-'.):-:[~E]:.=====::::::.:...--....;_---=(b) '""' (6) =; secreta ry@state.gov Subject: One Step COVID-19 test kit$ - IMMEDIATE AVAILABILITY Dear Mr . Vice President & Task Force Members My name is Jeffrey "Scott" Smith . I live in CbH KS. For the past 35 years I have been a Purchasing Agent in the private sector. Much of my career has dealt with China sourcing and supplier development. I have established a wide network of suppliers and contacts throughout China. You can see from my US Passport number CbH6)that I have traveled to China for the past 20 years ... including spending nearly CbH6Jmy time in 2018 & 2019 visiting China suppliers . (Thankfully I returned on 15-Nov-2019 , prior to the outbreak... CbH6) .) I was invited by one of my trusted suppliers to offer One Step COV ID-19 test kits to the United States. The Guangzhou based s~as CbH4>test kits available now for immediate shipment. T hey can produce ~ kits per week at their factory . Please see the information below and the materials attached for more information. This is a very cost effective test - and provides results in 15 minutes. I will trust you to determine the efficacy of the diagnostics. To be clear - this is not my business. I will profit in no way from providing these kits to the American healthcare public -- except for the sat isfaction of doing my patriotic duty to assist my fellow Americans. I fully understand the gravity and seriousness of this disease. All of my factories in China have, and are , suffering from the effect and fall out. My business in CbH6)is dealing with the effects of the supply chain disruptions. I hope that this offer , and availability of a additional test kit pipeline, will help ease the test kit shortage that we are experiencing in the USA . If you and your Procurement NIH-000848 Offices would like more information or would like to secure these test kits, please contact me . I can assist in arranging supplier contacts and immediate air shipments. I certainly thank you and the many dedicated leaders in the USA for your great work to combat COVID-19 - and for the care that you are showing the American public. Best regards, Scott Smith (b)(6) (b)(6) M: -------- Original Message -------Subject: One Step COVID-19test kit Date: 2020-03-07 2:41 am From: "JackScientek" To: (b)(6) Reply-To: Dear Scott, How are you? It was a great pleasure talking with you on Wechat, As we discussed, I have a friend who works in Wandfo Biotech Company in Guangzhou (a public listing company). They have developed a One Step COVID-19 test kit to screen the Corona virus in only 15 minutes. This test kit is been massively used in China and it's been suppl ied to Japan,South Korea, Ukraine and Iran to cope with the Corona Virus, It has also been certified by Chinese health organization and EU. I am wondering if you have any connection with any medical 4> organizations, if they need this kit, Wondfo is able to supply. CbH • Wondfo provide international shipping worldwide. Maybe this can be helpful for some people. Here below please refer to the most concerned informat ion: Name of the test kit: One Step COVID-19 Test (Chromatography Assay) Manufacturer: GuangZhou Wondfo Biotech Co.,Ltd NIH-000849 Name Quantity One Step COVID-19 Test Kit Unit Price - Packages K:arton Measurement ~olume(CB K;ross M) h,veight(Kgs) (b) (4) One Step COVID-19 Test Kit One Step COVID-19 Test Kit One Step COVID-19 Test Kit Price availability : 1 week (b) (4) Payme nt terms: Delivery term Avai labi lity : productio n capacity (b) (4) --- --------- For you r information, this testing kit has been supplied to Japan, and south Korea , lran, Ukraine , their production schedule is very tight, the factory may raise up price a week later. Other Available documents are attached for your reference. Best Rega rds JackJiang ~Scientek Scientek Electrical Co .,Ltd. ~ 86- 189-4246-9075 Q I I Mob/WhatsApp/Wechat Danzao . I (b)(6) : Nanhai District I Foshan,Guangdong I China 528216 -1J www .scientekpower .com l8l info@scie ntekpower .com CbH6J NIH-000850 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 8 Mar 2020 02:57 :55 +0000 Marston, Hilary (NIH/NIAID) [El To: (b) (6)' Cc: RE:NSCinquiry on treatment study Subjec t: See my changes in Red From: Marston, Hilary (NIH/NIAID) [E] Sen t : Saturday, March 7, 2020 6 :37 PM To: Fauci, Anthony (NIH/NIAID) [E]-----(b)( (b)(6 )> -= (b=H=6); Lane, Cliff (NIH/N IAID) [E] > Cc: Conrad, Patricia (NIH/NIAID) [El (b)( Eisinger, Robert (NIH/NIA ID) [El Subject: NSCinquiry on t reatment st udy -------- (b)(6)>; ·>; Lerner, Andrea (NIH/N IAID) [E) (b)(6) (b)(5), (b)(5) Sorry to add to the in box. NIH-00085 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 8 Mar 2020 02:08:47 +0000 Gregory Klomp RE: COVID-19 treatment To: Subject: We are pursu ing th is idea. From: Gregory Klomp Se nt: Saturday, March 7, 2020 8:06 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6) Subject: COVID-19 treatment It seems COVID-19 causes greater problems for the elderly and those with chron ic illnesses, as you have said. Why not try giving those with active disease, or those at risk, gamma-globu lin, to ame liorate the effects of the il lness? It would be especially interesting to prepare batches of gamma globulin using the blood (2,000- 3,000 dono rs) of people who have, or who have recovered from, COVID-19 infection. There is ample precedent for using Gamma-globulin to prevent or treat viral illnesses (Hepatitis A, B) or diseases of unknown etiology (ie Kawasaki's). This could be useful especially while we wait for the development of a vaccine . What do you think? Gregory Klomp, MD (b)(6) (I trained at Columbia-Presbyterian Hospital I see you were at Weil Cornell) NIH-000852 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 17:06:39-0500 NIAIDPublic Inquiries Fwd: From ERProvider,SomeCommonsenseCOVID-19addl. suggestions Sent from my iPhone Begin forwarded message: From: (b)(6) Date: March 7, 2020 at 4:08:23 PM EST ,--------;;-~ To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: From ER Provider, Some Common sense COVID-19 addl. suggestions Dr. Fauci: I have been following you and others on CSPANwith appreciation. 1) Please ensure you are all getting adequate sleep. (There is too much yahoo-machismo in our field) Please put forth recommendations for providers and their employe rs. 2) I see the CDCwarning about herbals, which I agree with except for one: echinacea, just about the only herbal with proven medical usefulness, not as it is recommended on the bottles or websites, but as only a single 2 capsules, on day one of viral ill ness. Echinacea demarginates the matured bone marrow leukocytes. Used as a "one shot deal" may decrease COVID-19 duration/severity as eg.: "take right away on day one, drink plenty of water and sleep as long as necessary". Please at least study the use of Echinacea in this manner for COVID-19. (Google is suddenly missing Echinacea's mechanism/use info, so please have this corrected, if for nothing else to prevent hoarding. One bottle can be for a whole neighborhood and please ask the drug stores to offer "two packs" with proper instructions. eg.: "take only two as soon as ill with cold or flu and not take more, but to replenish the immune system follow up with fresh fruits and vegetables, etc . 3) Make sure we have enough Ventolin, Proventil available so those with new asthmatic component due to COVID-19 can call their Dr. for RX if they cannot blow out a match, for instance, and use th e drive through i nstead of goin into the pharmacy. Consider hazmat for drive through testing and Rx pharmacy staff (as in S. Korea). I would be interested in knowing the percent of COVID-19 respiratory sufferers who can stay home but will need Ventolin.10%? (just a guess from seeing bronchitis in the ER). NIH-000854 4) Ensure all the medical providers with offices, give out their office telephone numbers and have staff trained to triage calls so people can stay home until they are well. 5) Ensure levothyroxine (the USmost common Rx) is made in the USAfrom ingred ients made in the USA. Ditto for down the line of the most necessary and common RX, including Ventolin, and the antibiotics that would treat bacterial superinfection of COVID-19 (particularly the ones that can be used at home: macrolides, etc.) 6) Encourage prevention of superinfection with clean respiratory toilet, hydration, chest PT preferred over suctioning , clean environment, including cleaning floors daily. One of the most successful methods of chest PT involves the patient lying on the bed with their face near the floor. Decreasing the load of pulmonary sputum is critical. 7) There is very large number of semi-retired physicians, such as myself who would probably like to be utilized (an paid a little) for te lemedicine to assist with triage. We can do telemedicine at home. I am not set up to do this but will soon be set up and able. We need to know which companies we can trust to hire us. There should be telemedicine training and tracking coming from t he CDCor other state and national governments. 8) Is the 3/3/20 John Kehoe Financial Times art icle correct? Is it not best to predict mortality so as to more realistically prepare for post-COVID-19 recovery economically and socially and give confidence by being transparent? I see recovery j obs being the young taking care of the old after most have had it and been cured or succumbed. Then the other half of the people w ill get it, too ... Is there some stigma attached to the word "infrastructure" that would prevent recovery of our economy? 9) I do not wee the recommendations for Flu and both pneumovax vaccines, but the recommendation needs to get out broadly right away. 10) Wuhan had to truck in food ...how are we planning? Canned food decreases one's immu ne system. Fresh fruits and vegetables, frozen or dried are needed. 11) China closed all the theaters ...and we should also start closing the use of public places, particularly asking folks in their 60's and older to stay home now. 12) Recommend providers write three month supply of Rx for all patients, to decrease visits out and ensure availability. 13) The closure of schools might spread COVID-19 unless children have food to eat at home and the parents comply. 14) Will census takers spread it? Should the census be postponed or performed via hazmat suit or in another fashion? This is a long list. Please look into 2-packs of Echinacea with instructions . Get enough sleep/stay wel l. Thank you. Best regards, Gretchen Boise, MD LL (b)(6) (caller must announce who they are) NIH-000855 (b)(6) NIH-000856 From: Date: (b)(6) Sat, 7 Mar 2020 16:15:52 -0500 To: Lane, Cliff (NIH/NIAID) [E) Fwd: Covid-19 Pandemic -- update Subject: FYI. I get 100 of these per day. Begin forwarded message: From: David Katz Cb)(6) Date: March 6, 2020 at 7 :46: 18 PM EST-----~~ To: "Fauci, Anthony (NIH/NIAID) [E]",___ _______ CbH6J Subject: Covid-19 Pand emic -- update Dear Tony: As I continue to follow the evolution of this disastrous calamity, 1 continue to think of possible approaches to dealing with therapeutic options that might be "off the beaten trail" but nonetheless worth considering - especially for those patients who are at high risk for debilitation and, possibly, death . I share one such thought with you here. Several years ago, recombinant Human Growth Hormone (rHGH) was reported to be significantly effective in restoring/ enhancing T cell anti -viral act ivity in patients infected with HlV (citation below): Growth hormone resurrects adult human thymus during HIV-1 infection Kiki Tesselaar, Frank Miedema J Cf in In vest. 2008; 118(3):844-847. http s://doi.org/ 10. l 172/JCI351l 2. My thought is that since, in many ways, elderly patients afflicted with COVID-19 fall into a similar category, that treatment NIH-000857 with rHGH might be an effective treatment alternative to employ during this immediate time frame while you are exploring more specific alternatives. I look forward to your thoughts on this, and best wishes, David (PS: I think you have handled yourself magnificently during these incredible press conferences, etc.!) NIH-000858 From: Date: To: Cc: -------- Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 19:06:14 +0000 Megan 8. Conrad, Patricia (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Greg Folkers (b ~ )~(6) = RE:Thank you, Dr. Fauci Ms. Fender: There is no such a th ing right now as "no risk" given the uncertainty of the current situation . However, in t he context of what we do know, since you are H years old, you have ----- Go about your usual business. You have no reason to panic. I hope that this is helpful. Best regards, A.S. Fauci From: Megan B. Date: Saturday, March 7, 2020 11:10 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Thank you, Dr. Fauci CbH6)> CbH6J> Dr. Fauci, I apologize to reach out, I know how extremely busy you must be. But I have always invested a great deal of trust in you . (b)(6) Thank you greatly. Sincerely, Megan Fender NIH-000862 On Sun, Feb 9, 2020, 6:27 PM Fauci, Anthony (NIH/NIAID) [E] --------- Cb H6J wrote : Megan: Many t hanks f or yo ur kind wo rds. They are much appreciated. Best rega rds, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 E-ma il: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Megan B. Date: Sunday, February 9, 2020 4:53 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Thank you, Dr. Fauci CbH6J> -------=-c-c= (b)(6J Dr. Fauci, As a citizen and mother , I would just like to take a short moment to say thank you for all of your great work and service to the American people . I have admired your work for many years, and appreciated your transparency during the Ebola crisis, as we ll as this most recent situation . As a citizen, I appreciate that you relay facts, both good and bad, and have established a sense of trust w ith the people . (b)(6) · W ith the Ebola crisis, and with Coronaviru s, I feel better when I see your press conferences and hear all of the work you and your team do to protect both UScitizens, and the world commun ity . Friday I was very happy to hear you announce the extreme progress that's been made in just two week's time on the vaccine, and that there have been no roadblocks . This has been done at unprecedented speeds, by what I'm sure are very talented scientists. Again, thank you for your lifetime of service in disease prevention, and for making citizens like myself feel bet ter knowing we have people like you and your team working tirelessly for the people. ) (6) ________________ , but I take comfort in knowing we have such great, 11111111 talented individuals leading our public health system. Dr. Fauci, you are truly a saint. Thank you for all that you do. NIH-000863 Sincerely, Megan Fender NIH-000864 From: (b)( 6) Date: Sat, 7 Mar 2020 13:37 :51 -0500 To: NIAID Public Inquiries Fwd: a question Subject: Sent from my iPhone B eg in forwarded messag e: (b)(6) From: Leonard Trudell Date: M arch 7, 2020 at 1:34: 34 PM E ST -------~~ To: "Fauci, Anthony (NIH/N lAID ) (E]" Subject: a question --------- --------- (bH6J · Dr. Fauci, May I suggest a question that you might ask of COVID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COV ID-19 corona virus basic construct is a basic flu version with a bio-engineered HIV or other(?) component , is it possible that our flu vaccines might have some degree of protection agains t this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trudell (b)(6) NIH-000865 Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 18:36:42 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: a question From: Date: To: Subject: Please have someone respond. From: Leonard Trudell Date: Saturday, March 7, 2020 1:34 PM --------- To: Fauci, Anthony {NIH/NIAID) [E] Subject: a question -----~~ (b)(6) ------- (b)(6)> Dr. Fauci, May I suggest a question that you might ask of COV ID-19 identified patients? Could you ask them if they had received a current flu shot for this season? Since the COVID-19 corona virus basic construct is a basic f lu version with a bio-engineered HIV or other(?) component, is it possible that our flu vaccines might have some degree of protection against this new COVID-19 viral construct? I think it is important to ask this question! Dr. Len Trude ll (b)(6) NIH-000866 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Sat, 7 Mar 202018:10:15 +0000 Richard Carmona RE: Kudos To: Subject: Rich: Many thanks for your kind note. Much appreciated . I hope that all is well with you . Best regards, Tony From: Richard Carmona -----------------.~ (b)( Date: Saturday, March 7, 2020 11:56 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Kudos -------- > (b)(6J> Tony, as always and for many decades and most importantly now, thank you for being the voice of reason and integrity that emanates from the political swamp to quell uncertainty and fear . Ironically your words now as a "vaccine" against the disease of public fear and uncertainty may be as important as the eventual immunologically derived vaccine against coronavirus you are working on. Be well, Rich Carmona Richard Carmona 17th Surgeon General of The United States Chief of Health Innovations Distinguished Professor University of Arizona 8600 E. Rockcliff Road CAN YONRANCH. 0: 520.749.7754 M: ___ Cb ...,).,.(6) __. canyonranch.com NIH-000869 I Tucson , AZ 85750 From: (b)(6) Date: To: Subject: Sat, 7 Mar 2020 11:19:16 -0500 NIAIDPublic Inquiries Fwd: universitycoronavirus From patty on asf phone. Pis handle Sent from my iPhone Begin forwarded me ssage : From 1< Date: ~ -ar-ch - 7,- 2-0-20 - at_ l_0_:0-6-:2_1_A_M _ E_S_T__ To: "Fauci, Anthony (NIH/NIAID) [E]" Subject: university coronavirus ---------::-,:-:-= --------- (b)(6) Hello and thank you for all of your tireless efforts in dealing with the coronavirus. I have a concern about the universities and the spread of this virus . Many schools brought back students from study abroad before the 14 day quarantine was put into place, and even after the quarantine was put in place, many students did not follow the quarantine rules. Also, with shared dorms and apartments it was not possible for student's who returned to campuses and not their homes. By the times schools came up with a plan for quarantining the student's it was well over a week after some were back. Therefore, there is potential for widespread infection. The vice president said the elderly and those w ith underlying medical conditions are at risk and should take caution in where they go, avoid crowded places etc..Millions of students have asthma, diabetes, auto-immune disorders, and they do not have a choice other than to go to class. The government does not seemed concerned about the potential spread among campuses and what a disaster this could be. They have voiced why grade schools are not closed (since younger are not at risks better for them to be at school) but they are ignoring college kids are at risk and the impact of widespread infection on a campus could be huge. Students i~ colleges travel back and forth to the city all the time , and I am concerned schools are not temporarily closing until more testing is available and we see where this goes. At minimum , giving student's with underlying medical conditions the option to go home and work remotely. Right now they do not have NIH-000870 any option other than to go to class. When questioned they say they are listening to the CDC and state government. (b)(6) and students are not following the advice to stay home sick and nobody seems concerned about trying to prevent infection. Can the government please look at a temporary ban on classes at Universit ies in states where infection is rapidly spreading, especially knowing there are not enough test available yet. The schools are not taking action on their own and this is a frustrating situation seeing delays in decisions making. Thank you for your time in consideration in addressing these concerns, Prefer to remain anonymous for the protection of Sent from Mail for Windows 10 NIH-00087 1 ---------- (b)( (b)(6) From: Date: Sat, 7 Mar 2020 11:16:57 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Re: Plasmapherese pediatricians to obtain anti-corona virus antibodies To: Subject: Sorry this is from patty. I have an iPhone just to manage h is email s so some of these are from me. Will add the letter p to the ones I send you so you know they are from me. Sent from my iPhone On Mar 7, 2020, at 10:46 AM , AuchincJoss , Hugh (NIH/NIAID) [E] (bH6J > wrote : Tony, as I told Pany yesterday, I am handling all that you send me but I' m not going to fill your inbox with an acknowledgement each time. Sent from my iPad On Mar 7, 2020 , at 9:15 AM , Fauci , Anthony (NJH/NTAID) [E] (b) (6) > wrote: Pls handle Sent from my iPhone Begin forwarded message: From: David Chung (b) (6J> Date: March 6, 2020 at 12:45: 17 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" (b)(6) > Subject: Plasmapherese pediatricians to obtain anticorona virus antibodies Dr. Fauci , I appreciate the efforts of the WHO taking a look into the temperature question. It is helpful to understand the virus and know what to expect. (b)(6) is a professional data analyst of large datasets like census NIH-000872 data, for example. I was wondering if it would be possible to obtain the WHO dataset to see if there were any angles not considered. I am certain that the WHO 's biostatisticians know what they are doing, but data is a funny thing. You get the answers to the questions you ask. If the right questions were not asked, you may miss useful information. Regarding the subject line, if the theory is true that children have some cross-reactive protection due to antibody production to the harmless coronavirus population , that would mean that pediatricians would also carry very high levels of protective antibody. If this is true, then plasmapheresis might provide anticoronavirus antibody as potential treatment. I do not know enough about plasmapheresis to know if this could be applied to scale but I wanted to pass along the thought CbH6) David Chung On Monday, March 2, 2020 , 07:46 :51 AM EST , Fauci , Anthony (NIH/NIAID) [E) (b)(6)>wrote: Thank you for your careful and well thought out note. Worthy of consideration. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: Cb)( FAX: (301 496-4409 E-mail: Cb)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives. NIH-000873 From: David Chung (b)(6) Date: Sunday, March 1, 2020 9:44 P _M _____ ~ = To: Fauci , Anthony (NIH/NIAID) [E] (b)(6) Subject: Pis advise to allow return air travel only , stop all other air travel Dear Dr. Fauci , Thank you for your leadership and guidance in this difficult time. I am a pediatrician in Massachusetts, and as you know , direct-linkage from travel cases are popping up on the East Coast. In order to keep the community viral load down , keeping new cases from moving around the country and the world will delay the spread and amplification of the vira l load. According to my observations, hot climates seem to be having a favorable new case rate . Based on the city of Qom versus the experience in Singapore and Australia, it appears that the transit ion temperature for efficient spread is somewhere above when there are highs around 50 degrees F, similar to H1N1 . According to my observations, prior to seasonal flu , the transition temperature was closer to highs of 40 degrees F. This theory should be testable . For example , there are new cases in Kuwait and Bahrain. If I am right , if you tested a subset of these populations , you would find a very high rate of asymptomatic infection , probably 80-90%, because that's how many people it would take to shed small amounts of virus to create a community viral load to make someone sick enough to get tested. If this is true , this bodes well for the virus burning itself out to endemic status relatively quickly. This would be very reassuring data you could provide to reduce panic - if you can tell people you know how long this pandemic is going to last rather than saying that we don't know . Although some experts may say that restricting travel w ill on ly delay the inevitable, this is not a valid statement if the transition temperature for effect spread really is 50 degrees. A delay of significant community spread in the US until highs reach the 50s for the Northeast where the population is the most NIH-000874 dense would have a massive life-saving effect , but if this is to occur, the flight restriction needs to happen now. Stopping all flights would be impractical and inhumane, but allowing return flights only and stopping all other air travel would be effective . It would have a massive effect on the economy, but so will overwhelming corona virus infection. No one will die because they can't take a vacation or business trip . Financial losses would need to be settled later, so this would require emergency declarations , etc. If you wanted to take it in a step-wise manner , you could start with international flights and then move on to domestic flights if necessary - this would probably be wise and would have a less severe impact on the economy. Thank you again, and I am sure this is one of thousands of unsolicited emails . I wish you the very best and God grant you w isdom. Best, David Chung Pediatric Associates of Brockton NIH-000875 From: (b)(6) Sat, 7 Mar 2020 09:17:55 -0500 To: Cassetti, Cristina (NIH/NIAID) [E] Subject: Fwd: ACE2 neutraliz ing antibody from R&D Systems Attachments : SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2and is blocked by a clinically-proven protease inhibitor.pdf , ATTOOOOl.htm,Crystal structure of the 2019-nCoV spike recept or binding domain bound with ACE2 receptor .pdf, ATT00002.htm Date: Sent from my iPhone Begin forwarded message: From: Hung Trinh (b)( Date: March 5, 2020 at 11:04:5 1 PM EST To: "Fauci , Anthony (NIH/NIAID ) [E]" (bH6J Subject: Fwd: ACE2 neutralizing antibody from R&D Systems -------= = NIH-000876 From: (b)(6) Date: Sat, 7 Mar 2020 09:12:07 -0500 To: Auchincloss, Hugh (NIH/NIAID) [E];Folkers, Greg:(NHf/i\llAlD) JE] Subject: Fwd: Blog Clearance Request: COVID-19: Potent ia l lrfrp!icati6hs for Hfdividuals with Substance Use Disorders Attachments: COVID SUD blog ebe3 ew6 sw2 ndv4 CLEAN.docx, ATTOOOOl.htm Pls handle Sent from my iPhone Begin forwarded message: From: "Volkow , Nora (NIH/NIDA) [E]" (b)( > Date: March 6, 2020 at 4:46:06 PM EST -------~~ To: "Fauci , Anthony (NlH/NlAID ) [E]" (bH6J· Cc: "Hobin , Jennifer (NIH/NIDA) [E]" (bH6J>, "Volkow, Nora (NIH/N IDA) [E]" (bH6J> Subject: Blog Clearance Request: COVID-19: Potential Implications for Individuals with Substance Use Disorders Dear Toni. John Burklow asked NIAID to review a Blog I wrote on the need to evaluate vulnerabilities among patients with substance use disorders to COVID-19. Let me know if u or your staff have concerns or suggestions. I realize u are totally swamped and I apologize for burdening u with it. Best nora NIH-000877 From: Date: (b)(6) To: Subject: Attachments : Sat, 7 Mar 2020 09 :11:12 -050 0 Auchincloss, Hugh (NIH/ NIAID) [E] Fwd: JID 2006, 193:1244 -1249 SARS & gd T cells.pdf, ATT00001.h tm Pis respond if required Sent from my iPhone Begin forwa rded message: _______ From: MIRO SLA V MALKOVSK Y ....,.... Date: March 6, 2020 at 4:46:28 PM EST To: "Redfield, Robert R. (COC/OD) " Cc: "Fauci, Anthony (NIH/NJAID) [E]" _______ Subject: JID 2006, 193:1244-1249 (b)(6) -----=-:--=(b)( 6) (b_H_6J Dear Bob, Long time, no see. Our SARS study (JID 2006, 193:1244-1249; see the attachmen t) showed selective expansions of Vy9Vo2 T cells in survivors of SARS-CoV infection. Interestingly , stimulated Vy9V62 T cells also display an interferon-y-dependent anti-SARS-CoV activity and are able to directly kill SARS-CoV-infected cells. Since it is very easy to activate human Vy9Vo2 T cells in vivo (e.g., using FDA-approv ed and relatively non-toxic drugs for treating bone-demineraliza tion) and given the simi larities between SARSCoV and SARS -CoV-2, I thought that it cou ld be potentially useful to bring these facts to you r and Tony 's attention , in spite of knowing that both of you are probably slightly busier these days than you would like to be. All the best and good luck with everyth ing, Yours as ever, Mirek M. Malkovsky , MD, PhD, FRCPath Professor Emeritus, UW School of Medicine and Public Health Mobile: (b) (6) Office telephone and fax: (b)(6) E-mail: (b)(6) NIH-000878 From: Date: To: Subject: (b)(6) Sat, 7 Mar 2020 09:07:07 -0500 Auchincloss, Hugh (NIH/NIAID) [E] Fwd: Pneumococcus vaccination in relation to coronavirus infection . Pls respond Sent from my iPhone Begin forwarded message: From: Lar s Nie lsen (b)(6) > Date: March 6, 2020 at 8:07:37 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (b)( Subject: Pneumococcus vaccination in relation to coronavirus infection. ,-------- ~= De ar Anthony Fauci, As l und erstand the fa tal cases of covid-19 develop pneumonia after severa l days of symptoms of the acute viral infecti on. In this way the present conoravirus infection is very like our present and previous fatal influenza virus infections. In the 1918 pand emic many if not most of the fatal cases were caused by bacterial superinfection with hemolytic streptococci and pneumococci. The former is rather se ldom now, but the pneumococcal infections are common. Should we advice persons over >65 y as well as people with chronic diseases with increased risk of fatal co ronavirus diseases to be vaccinated against pneumoco cci now? My best regards and thank you for your significant contribut ion to inflammato ry medicine and infections. Lars P . Nielsen, M.D . Specia list in Medical Microbiology and Virology Forme r head of the Danish National Influenza Laboratory. NIH-000879 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:25:29 +0000 Elizabeth Stevens RE:Thank you for staying front and center, and in the public eye re COVID-19 Ms. Stevens: Thank you for your kind note . Best regards, A .S. Fauci ---------- (b)(6) From: Elizabeth Stevens Date: Friday, March 6, 2020 10:30 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Thank you for staying front and center, and in the public eye re COVID-19 --------- Dear Dr. Fauci, I am so happy to continue seeing you in press conferences and on news broadcasts. Please keep making those pub lic appearances. Amer icans need to hear the facts from someone who is trustworthy . I am sure that tiptoeing around Donald Trump has dramat ically complicated your life . I hope that you will find ways to " correct" or "clarify" the constan t stream of misstatements that he makes- our lives depend upon it . (Maybe Trump could wear a hazmat suit - to protect his frag ile ego from any possible bruising caused by a collision with the truth. Just kidding.) Seriously, Doctor, it is a huge relief to see and hear you and your expert colleagues . It is to the point that we cannot believe a single word tha t comes out of Trump's mouth. Very sincerely, Elizabeth Stevens (b)(6) NIH-000880 From: Date: Fauci, Anthony (NIH/N IAID) [E) Sat, 7 Mar 2020 13:23:54 +0000 _________________ (b)(6) To: FW: Subject: ___. (b) (4) fyi From: Lipkin, Ian W (b)( ------------" Se nt : Saturd ay, March 7, 2020 8:20 AM To: Fauci, Anthony {NIH/NIAID) [E]------~= Subject: > ___________________ (b)(6) ___. (b)( 4) Tony, (b)(4 Happy to connect you w it h Zhu. (b) (4) NIH-00088 1 (b)(4 l NIH-000882 (b) (4) NIH-000883 (b) (4) NIH-000884 (b)(4) NIH-000885 (b) (4) »» Wit h best regards, >>>> »» Zhu >>>> >>>> >»> ~ 1~ A: Lipkin, Ian W. -------------- » » ~3!Bt fsJ: 2020~2)=19 8 23 :01 »» >»> ~~i4 A: Zhu Chen :t'J>i!: George Gao; zhangzongwei »» ~~: Re: important info >>>> >>>> Zhu, (b)(6) »» Please call me on >>>> >>>>Ian >>>> >>>> >>>> »>> W. Ian Lipkin, MD »» John Snow Professor of Epidemiology and Director »» Center for Infection and Immunity >»> Mailman School of Public Health >>>> >»> Professor of Pathology and Neurology »» College of Physicians & Surgeons >>>> Columbia University »» 722 West 168th Street, 17th Floor »>> New York, NY 10032 »» Voice: (b)(6) >»> Fax: (212) 342-9044 (b)(6) >>» Email: ----- ----------- NIH-000886 (b)( >>>> »» Administrative Coordinator >»> (b)(6) >>>> Voice: »» >>>> »» »» Email: (b)(6) ~====::::!!:,__~ = (b)(6) --------- www.cii .columbia.edu Follow CII on Twitte r: CII_Columbia I Facebook: ClI.Columbia >>>> >>>> >>>> >>>> >>>> >>>> >»> On Feb 9, 2020, at 9:43 AM, ZhuChen >>>> ------- (b)(6)> wrote: >>>> Dear Ian, »» I have an important info to be shared with you. According to the latest report from the National Health Commission, the number of confirmed cases of NCP (2019-nCoV pneumonia) in other Provinces than Hubei {Wuhan is the capital city) was decreased from 890/day on Feb 3rd to 509/day on Feb 8th . So it is still possible for this outbreak to be basically contained in China. »» Therefore, my suggestion is that we support the current public health policies and strategy to concentrate quality med ical human resources and other resources to save more life of severe pat ients, even though the cost is high, very high. And then, we shall continuously analyze the situation for possible adjustment of policies and measures. >>>> Best, >>>> Zhu >>>> >> NIH-000887 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:23:10 +0000 Lorne Brandes RE:Coronavirus immunity We have thought about it. -----Original Message ----From: Lorne Brandes ______ r-:;; (b'"")'"" (6) = Date: Saturday , March 7, 2020 12:51 AM To: Fauci, Anthony (NIH/NIAID) [E]...______ Subject: Coronavims immunity ------~~= Cb _> _<.... Hi Dr Fauci , Has anyone considered the possib ility that previous coronavims infection(s) associated with common colds may result in at least partial immw1ity to the COVID-19virus? This may expla in why the disease is generally mild in 80% of adults and apparently rare in children (most of whom get more frequent colds than adults). I would be pleased to hear your thoughts. Sincerely, Lome Brandes, MD, FRCPC Professor, University of Manitoba (b)(6) NIH-000888 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:21:56 +0000 Ann Job RE:2020 Censusand COVID-19 Ms. Job: Thank you for your note., Best regards, A.S. Fauci From: Ann Job (b)(6)> Date: Saturday, March 7, 2020 12:18 AM To: Fauci, Anthony (NIH/NIAID) [E] ------~= Subject: 2020 Censusand COVID-19 --------- (b)(6) Dear Dr. Fauci , Today I wrote and mailed a letter to both you and Dr. Redfie ld. I will not duplicate nor attac h it her e, but I did want you to make you aware of my letter in case it doesn't reach your desk on Monday. In it I ask you and Dr. Redfie ld to explore the possibility of using 2020 Census Enumerators as an "on-the-gro und army" to help stop COVID-19 . Because as you know better than anyone else that time is of the essence, I thought it useful to give you a heads-up about my letter via this email. I am probably being na ive, but just in case it make s sense to you , I thought it cou ldn't hm1 to write you . Thank you for being there for us. We really need you . Yours, Ann E. Job (pronounced like the Book of Job in the B ible) (b) <~(iPhone) (hom e) NIH-00088 9 From: Date: To: Subject: Attachments: Fauci, Ant hony {NIH/ NIAID) [E] Sat, 7 Mar 2020 13:13: 58 +0000 Eisinger, Robert {NIH/ NIAID) [E] FW: A vaccine w ith ant i imm unosuppre ssive prope rties (b)(6) Please respond on my behalf --------- From: Avr aham Halbrei ch Date: Satur day, Ma rch 7, 2020 7:00 AM To: Fauc i, Ant hony (NIH/NIAID) [E] ..------ (b)( 6)> -,.(b'""' H= > Subject: A vaccine w ith anti lmmunos uppressive properties Importance : Low Dear Dr Fauci , Common wisdom tells us that the inability to immunize against HIV, malaria etc. as well as the need to repeat evry year anti flu vaccination result from the excessive , or limitless, genetic variability of the underlying pathogens. While not doubting the reality of this genetic variability , best observed in an orderly manner in the case of HIV, I considered the possibility that these pathogens are endowed wiith an immunosuppressive capacity that is not inactivated during vaccine production, and that current vaccines do not induce immunity against such immunosuppression. I applied this reasonning when I work ed on an AIDS vaccine in 1991 in Zagury's lab (Halbreich A et al. (1992) Vaccine Research,4 :397-412 ). Indeed , we tested then , in suitably immunized animals , the effect of the various preparations on the cellular response to tuberculin and the capacity of animals to be Immunized against tuberculin and tetanus as a function of the exrent of treatment. The immune response to these agents was indeed higher in the presence of hivions compared to heat inactivated preparations . This HIVION preparat ion was used on 6 patients in Zaire (Zagury et al. ( 1992) J Acquired Immune Deficiency Syndromes, 5 :676-681). NIH-000890 Unfortunately, when I tried to make a greater prep for a phase I trial , the viral preparation turned out (too late) , by SOS gel elecrophoresis , not to contain any viral protein , due either to degradat ion or another mishap . I left Zagury 's lab soon after and it was impossib le for me later to obtain material (either viral or from recombinant protein) to further advance the matter. I do believe that tuning vaccine preparation to counter immunosuppressive effe ct of the virus (parasite) while preserving its capacity to induce anti viral immunity should resolve the need to revaccinate every year against the same virus. In fact, identifying the epitopes , acting for immunity and those acting against immunosuppression, at a later stage should allow a better result than we obtained. (It is not yet known whether corona virus also mutates rapidly, but I heard that a woman was reinfected after having recovered from covid-19 infection and this might indicate a capacity of the virus to counteract the host's immune response. In Cb H 6) I have been itching ever since to go back to unfinished projects , but did not find an avenue. Now, with the outburst of the corona virus pandemic this surfaces again . (b)((;J Sincerely Avraham Halbreich NIH-00089 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sat, 7 Mar 2020 13:06:00 +0000 Anderson, Jennifer (NIH/NIAID) [E] RE: unit heads To: Subject: If I am available, I would be happy to discuss COVID-19 From: Anderson, Jennifer (NIH/NIAID) [E] Date: Saturday, March 7, 2020 8:03 AM To: Fauci,Anthony (NIH/NIAID) [E] ------=-c Subject: Fwd: unit heads ---------- (b)( (b)'""' (6) = Good morning Dr Fauci We are - for the momen t - scheduled for a Un itheads meet ing on Tuesday. Tae Wook is next to pr esent but suggested (see below) that we make it a round table and discuss COVID-19. Question: IF Unitheads isn' t canceled how do you feel abou t having a Roundtable instead of Tae Wook presenting? Or would you prefer to take a break from Coronavirus for a moment and hear about HIV! Thanks Jen Sent from my iPhone Begin forwa rded message : From: "Chun, Tae-Wook (NIH/NIAID) [E]" Oate: March 6, 2020 at 9:53 :11 AM EST To: "Anderson, Jennifer Subject: Re: unit heads --------- ---------~~ (NIH/NIAID ) [E]" ----------- CbH6J> Can we do round table? I want to talk to him about corona not to mention the MTA will get canceled anyway . If you want me to I wi ll present . On Mar 6, 2020, at 9 :47 AM, Ande rson, Jennifer (NIH/NIAID) [E] (b)(6) wrote : Hi Tae Wook, NIH-000892 I thin k you are up for Unit heads? It's been so long, I've lost tr ack . I think you were supposed to present back on Jan 14th but it got canceled and I don 't th ink we 've had a pre senta tion since . Im being t old w e might have a UH on Tuesday-ASF is free so far . Can you present ? Jen Jennife r M. Anderson, PhD Deputy Branch Chief IAMB/OAS/N IAID Scientific Operations Manager LIR/DIR/NIAID 9000 Rockville Pike, Bldg. 10 Rm. 6A19A Bethesda, Mary land 20892 Office Phone : (b) (6) NIH Cell: Personal Cell: (b)(6) ----- (b)(6) FAX: 301-402 -4122 NIH-000893 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sat, 7 Mar 2020 13:02:34 +0000 Cassetti, Cristina (NIH/NIAID) [El;Lane, Cliff (NIH/NIAID) [El FW: Plasma therapy FYI --------- == -----Original Message ----From: Lipkin, Ian W. _________ Cb _> _<_, Date: Saturday , March 7, 2020 7:50 AM To: Fauci, Anthony (NIH/NIAID) [E] ..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on pi lot study of plasma therapy for COVlD -19. Sufficiently encouraging that J' d begin collecting p lasma for compassionate use as well as larger randomiz ed trial. Jan Jan NIH-000894 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 7 Mar 2020 13:02:18 +0000 Lipkin, Ian W. RE:Plasmat herapy Than.ks, Ian ---------, ~= -----Orig inal M essage ----From: L ipkin, Ian W. _________ Cb _)_(_. 6l> Date: Saturday, M arch 7, 2020 7: 50 AM To: Fauci, Anthony (NIH/NIAID) [E]..._______ Subject: Plasm a therapy ------~~ Cb _)_(6) ... Tony, Just reviewed paper (b) (4 on p ilot study of plasma therapy for COVlD-19. Sufficiently encouraging that J' d begin collecting p lasma for compass ionate use as well as larger randomized trial. Jan Jan NIH-000895 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 23:44:54 +0000 Folkers, Greg (NIH/NIAID) [E) Crawford , Chase (NIH/ NIAID) [E] Re: ASF------- AIPAC reports that two people who attended its conference To: Cc: Subject: tested positive for the co ronavirus Attachments: imageOOl.jpg Yikes! On Mar 6, 2020, at 6:23 PM , Folke rs, Greg (N IH/NIAID) [E] (b)(6) wrote: Just fyi -folks from this delegation wer e in the hallway on the Hill when you and Chase were the re From: Folkers, Greg (NIH/NIA ID) [El (b)(6) Date: Friday, March 6, 2020 6:18 PM Subject: JTA:AIPACreports that two people who attended its conference tested pos itive for the co ronav irus AIP AC reports that two people who attended its conference tested positive for the coronavirus MARCH 6, 2020 5:45 PM Outside the American Israel Public Affairs Committee (AIP AC) annual conference in Washington, DC on March, 01, 2020. (J\1arvin Joseph/The Washington Post via Getty Images) NIH-000896 WASHINGTON (JTA) - The American Israel Public Affairs Committee said that at least two people who attended the lobby's policy conference have tested positive for the . coronaVIrus. The conference, which ran from Feb. 28-March 2, drew 18,000 activists to Washington. The AIPAC statement posted late Friday on Twitter said the two people who tested positive are from New York. The outbreak has been especially hard on the Orthodox Jewish community in Westchester County, and AIPAC listed the county's health department as among the authorities with which it is in communication. The others are the New York Health Department, national health authorities and the District of Columbia Health Department. The statement also said the lobby was consulting with Edward Septimus, a professor of internal medicine at Texas A&M University. The statement posted on Twitter said an email was going out to all attendees as well as to congressional offices. The conference routinely attracts a majority of Congress members and their staffers. BY RON KAMP EAS NIH-000897 NIH-000898 From: (b)(6) Fri, 6 Mar 2020 18:35:49 -0500 NIAIDPublic Inquiries Fwd: Important & EmergencyNature (COVID-19)Related Date: To: Subject: Sent from my iPhone Begin forwarded message: From: Udita Katugampola (b) C Date: March 6, 2020 at 6:29: 16 PM EST ,--------;;-~ To: "Fauci , Anthony (NIH/NlAID ) (E]" (b)( Subject: Important &Emergency Nature (COVID-19) Related Dear Dr. Fauci, I saw that you are discussing the steps we need to take to make the impact of COVID-19 a minimum in CNN and decided to write to you what we did as faculty in this aspect. I believe that prevention is m uch more important than treatment later. As a preparation for the COVID-19 outbreak, two days ago, I made a personal decision to make all my homework on line submission so that we may avoid the spread of the virus anymore . Students work on homework for hours and can easily spread the virus without knowing it. Once it goes to graders (my TAs), they then spread it to the rest of the class, again without knowing it. Thus, an innocent act can be devastat ing. So, in simply two-three days it may spread to another 100 new indiv iduals easily. Graders may act as hubs in this case. The danger is, it may have spread to another hundred or more new individua ls even before it comes to a detectable level f rom any test. I also want to emphasis the following points: 1. We hear in all news that elderly people are the most vulnerable. But I think it should be corrected as people with immunodeficiency are the most vulnerable and elderly are in that category. Some one who is 10 years old and have diabetic or HIV has the same danger as an elderly person . 2. We should come up with a test such as a pregnancy test, which can be done at home without leaving their homes. This stops further spreading. 3. We should discuss foods that help cure it fast and th ings that we should not do. NIH-000899 I have shared my thoughts with CNN (Dr. Sanjay Gupta and Anderson Cooper as well). Thank you for your time and everything you do to our community at this critical moment . Best, Udita Udita Katugampola, Ph.D . Assistant Professor of Ma themat ics Florida Polytechnic Univer sity Office: !ST 2015 Tel: (b)(6) Email. (b) (6'i, edu Web:https ://sites. google.com/site/uditanalin/ NIH-000900 From: (b)(6) Date: To: Fri, 6 Mar 2020 18:32:06 -0500 NIAID Public Inquiries Subject: Fwd: MOSQUITOES Sent from my iPhone Begin forwarded message: From: JAME S NUTILE Date: March 6, 2020 at 5:58:58 PM EST ,------To: "Fauci , Anthony (NIH/NlAID ) (E]" Subject: MOSQUITOES ---------- (b)(6) -------- --;;-~ (b)( Dr. Fauci, No ones address ing the possibi lity of the Coronav irus being transferred by mosquitoes this summer. Is that a possib ility? Thank you, James Nutile Sent from my iPhone NIH-000901 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:31:39 -0500 NIAID Public Inquiries Fwd: I am not spam. Possible consideration for Coronavirus Sent from my iPhone Beg in forwarded message: From: Karen Bender (b)(6) > Date: March 6, 2020 at 6:07:58 PM EST To: "Fauci, Anthony (NIH/NlAID ) (E]" (bH6J · Subject: I am not spam. Possible consideration for Coronavirus -------~~ Good Evening Dr Fauci , I have an idea for your consideration for the Coronavirus vaccine/treatment. Noting that the virus is attacki ng ou r elderl y more and knowing their lungs are o lder and not as functi onal to fight this infection. Have you conside red artific ial surfactant to boost lung function. (b) (6) Perhaps if their lungs are stronger to expand they could fight the virus better. Thank you for listening, My prayers are with our Healthcare Professional s to achieve a treatment/vaccine. Karen Bender NIH-000902 From: (b)(6) Date: To: Subject: Fri, 6 Mar 2020 18:28:43 -0500 Lerner, Andrea (NIH/NIAID) [E);Auchincloss, Hugh (NIH/NIAID) [E) Fwd: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Can one of you take this? Sent from my iPhone Begin forwarded me ssage: From: Raja R (b)(6) > Date: March 6, 2020 at 6: 15:37 PM EST To: "Fauci , Anthony (NIH/NlAID ) (E]" <{,----~(b~ Subject: Kidney Disease (NS-MCD) and Covid-19 Coronavirus Dear Dr. Fauci, I live in the United Kingdom and listen to your recent press briefings from White House. First of all, I want to convey my sincerest thanks to you for providing valuable information to the general public. I would greatly appreciate it if you can advise on what precautions I should take -- . Should he try to avoid all social contact, and of course avoid any cruise, air or pub lic transport to prevent him from gettin g the infection? I would greatly appreciate your advice on thi s. Regards Raja NIH-000903 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 15:26:21 +0000 Dzau, Victor J. RE: URGENT- GPMB COVID-19 FUNDING NOTE Please leave m name off . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Ozau, Victor J. (b)(6) Date: Friday, March 6, 2020 10:02 AM -------::-::-=, To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Cc: Alex Harris (b)( ; Jeremy Farrar Subject: Re: URGENT- GPMB COVID-19 FUNDING NOTE ---------- (b) (6)> Tony, I know you are extremely busy. I am following up on GPMB business. Given our conversation 3 days ago, would you like to sign on the statement or do you prefer us to leave you name off? Please let us know ASAP. Best, Victor On Mar 5, 2020, at 9:31 AM , Alex Harris ---------- Dear Board Members, NIH-000904 (b)(6)> wrote: (b) (4) With many thanks, Alex Alex Harr is Head of Global Policy & Advocacy Wellcome T: (b)(6) (b)(6) G7 leadersand Sherpas Country Rep Canada Justin Trudeau, Prime Minister France Emmanuel Macron , President Germany Angela Merkel, Chancellor It aly Giuseppe Conte, Prime Minister Japan Shinz6 Abe, Prime Minis t er United Kingdom Boris Johnson , Prime Min ist er United States Do nald Trump, Sherpa(amendmentswelcome) GPMB lead(s) (b)(6) Jeremy Farrar u ~ Jeremy Farrar Victor Dzau NIH-000905 President Participants (b}(v European Union Charles Miche l, President of the Euro12eanCouncil European Union Ursula von der Le~en, President of the Euro12ean Comm ission International financial institut ions Institution Leadership Victor Dzau Jeremy Farrar Sherpa/equivalent or suggestedcontacts GPMB lead (b) (6), (b) <4Y Victor Dzau As Sy Jeremy Farrar NIH-000906 From: Alex Harris Se nt: 03 March 2020 23:06 To: 'Amelie RIoux• -------""' (b)(6) Cb "'>""'" <6) =>; Dzau, Victor J. Jeremy Farrar (b)( >; Anthony (b)(6)> ; Fore Henrietta (b)(6)>; Gao Fu (b ~ )~( ~ > -; G - as-humba Diane (b) (6) Ilona (b)(6) -:---:-.:======~~;---:--====~~-:----:-Fauci --~===: (b)(6)> ; Suzuki Yasuhiro (b)(6) ; Kiekbusch -----!:=====~~-::.=======~---(b)(6); Vega Morales Jeanette (b)(6); ----------- VijayRaghavan Krishnaswamy (b)(6)> (b)(6J>;Skvortsova Veronika Cc: Gro Brundtland CbH6)>;Elhadi SY (b)(6)>; Tore Godal ______ ; Godal, Tore (b)(6)>; (b)(6); SCHWARTLANDER,Bernhard F. (b)(6J>;RYAN, Michael J. (b)(6J>;Pate Muhamed (b)( 6) >; Kanarek, Morgan (b)(6) ::========~~-:-'."':"":"" ~======~~- ; William Hall ._________ ":"":":7:'"""---:---:-:----::;========;__---=---c-= Miller de Vega (b)( >; 'Marston Hilary' ; 'Sheila Austria' (b)(6); __ Teresa Subject: RE: GPMB: COVID-19 FUNDING NOTE Dear Board Members, Ahead of the GPMB Board call on Wednesday, I'm pleased to attach a note (on behalf of Jeremy Farrar, Victor Dzau and a small working group) setting out the urgent need for new funding for th e global COVID-19 response. You will have seen the strong announcement today from the World Bank of up to $12bn to support country response, wh ich we warmly welcome . We are asking for your feedback on the call and (b) (4) (b) (4) NIH-000907 (b) (4) We look forward to the discussion. With best wishes, Alex Alex Harr is Head of Global Policy & Advocacy Wellcom e T: (b)(6) (b)(6) NIH-000908 To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 15:23:33 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Folke rs, Greg (NIH/NIAID) [El;Conrad , Patricia (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch From: Date: Looks fine. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX : (301) 496-4409 E-mail : (b)(6l The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Stover, Kathy (NIH/NIAID) [El (b)(6)> Date: Friday, March 6, 2020 10:20 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6J> Cc: Billet, Courtney (NIH/N IAID) [El (b)(6) >; Folkers, Greg (NIH/NIAID) [E] _______ Cb _>_ <6l;Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft PRre: Phase 1 mRNA coronavirus vax launch ------ ::;..,..-,= Good morning, Dr . Fauci, Please fi nd attached for your review a draft press release about the launch of the Phase 1 study of the mRNA COVID-19 vaccine. We are tentative ly planning to issue the release on Wed ., March 11 once we ' ve received confirmation that the first participant has been vaccinated. For ease of reference, the following is the q uote we have crafted for you : "Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said NIAID Director Antho ny S. Fauci, M.D. "This Phase 1 study, launched in record speed, is an important first step toward achieving that goal." Thanks, NIH-000909 Kathy Kathy Stover Branch Chief News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases National Institutes of Health 31 Center Drive, Room 7A17F Bethesda, MD 20892 (b)(6) Media line: (301) 402-1663 NIH-000910 To: Fauci, Anthony (NIH/NIAIO) [El Fri, 6 Mar 2020 14:50:15 +0000 (b)(6) Subject: FW: Developing Immunity to SARS-CoV-2and lvlg From: Date: Please respond to th is person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Dr. Art Kamm Date: Friday, March 6, 2020 7:47 AM To: Fauci, Anthony (NIH/NIAID) [El -------::-:-:-= (b)(6>l>;Lane, Cliff (NIH/NIAID) [E] (b)(6)> Subject: Developing Immunity to SARS-CoV-2and lvlg Dear Dr. Fauci and Dr. Lane: I have been fo llowing the growing international outbreak of COVID-19 and wanted to share a thought with you, understanding that this may have already been thought of. My early academic research (refe rence provided, PNAS)involved cancer immunology where it contributed to a growing body of info rmation that certain tumor cells could possessunique surface antigens that could be used for immunologi c therapy (https://www .pnas.org/co ntent/pnas/7S/12/S9 12.fu ll.pdf ). My career then too k me to executive and senior executive/corporate officer positions in publicly-held pharmaceutical corporations (Glaxo and Salix, respectively) overseeing R&D of therapeutic agents. My experience has included both pharmaceuticals and biologics. (b)(6) Our current understanding of COVID-19 mortality is that it appears to be concentrated in the elderly and those with underlying medical conditions. In healthy indiv iduals (although still early) it appears that many of NIH-0009 11 those infected with SARS-CoV - 2 may remain symptom free or develop mi ld disease, or recover from mo re severe illness. Currently there are te ns of thousands of individua ls who have been identified as having been infected but are considered 'recovered' . That being case it wou ld seem plausible that they have mounted an antibody response to the vir us. The question is whethe r these individua ls are being tested for ant ibody titre to the virus, and if that is occurring whethe r they are being approached to donate plasma to move into lglv prod uction. With this illness still in it s early stages and being international, I would imagine that such an effort would involve a public/private sector endeavor. Understanding the difficulty in developing a vaccine fo r 'cold viruses', lvlG may be a way to at least reduce the mortality in our most vulne rable patients . So, the slow start we have had in t esting the US popu lation for this virus goes beyond disease prevention - it would certa inly be affecting our ability, to some degree, of rapidly developing a more ta rgeted intervention for high risk patients . Again, you may have already thought of this, but as a concerned citizen having some background and an (b)(6) ,I wanted to share these thoughts . Understanding your busy schedules, I have copied both the Director and Deputy Director for Clinica I Research and Special Projects. ---------Respectfully submitted, Arthur R. Kamm, PhD (b)(6) NIH-000912 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 14:48:03 +0000 Corey MD, Larry RE:A query To: Subject: Visit where? Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institute s of Health Bethesda, MD 20892 -2520 Phone: CbH6) FAX: {301) 496-4409 (b)(6) E-ma il: The info rmation in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the orig inal intended recipient . If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. -------- ________ -----Original Message---------From: Corey MD, Larry Date: Friday, March 6, 2020 8:18 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: A query _,, (b) (6)> ------ ---..---.--.,= CbH6J> Should i and I the younger Glenda Gray give these 702 tal ks at CROIon This coming Tuesday in Bosto n. If I fly East for this Tuesday evening t alk are you at all free Wednesday to come visit and tal k about HIV antibodies? Or are you so progr ammed with coronavirus thi s is not realistic . ? Sent from my iPhone NIH-0009 13 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:56:55 +0000 McNeil, Donald (mcneil@ nytimes .com) FW: NYT: Inside China's All -Out War on the Coronavirus Donald: You r interv iew w it h Bruce Ay lwa rd was t he best di scussion of COVID-19 t hat I have seen t hus far. Great job! Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/ NIAID) [E] CbH > Se nt : Thursday, March 5, 2020 11:19 PM Subject: NYT: Inside China's All-Out War on the Coronavirus Q&A Inside China's All-Out War on the Coronavirus Dr. Bruce Aylwa rd, of the W.H.O., got a rare glimpse into Beijing's camp aign to stop the epidemic. Here's what he saw. NIH-0009 14 Dr. Bruce Aylward, leader of the W.H.O. team that visited China to assessthe country's response to the coronavirus outbreak.Cred it ...Salvatore Di Nolfi/Keystone , via Associated Press By Donald G. McNeil Jr . • March 4, 2020 As the leader of the World Health Organization team that visited China, Dr. Bruce Aylward feels he has been to the mountaintop - and has seen what's possible. During a two -week visit in early February, Dr. Aylward saw how China rapidly suppressed the coronavirus outbreak that had engulfed Wuhan, and was threatening the rest of the country . New cases in China have dropped to about 200 a day, from more than 3,000 in early February. The numbers may rise again as China's economy begins to revive . But for now, far more new cases are appearing elsewhere in t he world. China's counterattack can be replicated, Dr. Aylward said, but it wil l requi re speed, money, imagination and political courage. For countries that act quickly, containment is sti ll possible ''because we don't have a global pandemic we have outbreaks occurring globally," he added. NIH-000915 Dr. Aylward, who has 30 years experience in fighting polio, Ebola and other global health emergencies, detailed in an interview w ith The New York Times how he thinks the campa ign against the virus should be run . This conversation has been edited and condensed. Do we know what this virus's lethality is? We hear some estim ates th at it's close to the 1918 Spanish flu, which killed 2.5 percent of its victim s, and other s that it' s a littl e worse th an the seasonal flu, which kills only 0 .1 percent. How many cases are missed affects that . There's this big panic in the West over asymptomatic cases. Many people are asymptomatic when tested, but develop symptoms within a day or two. In Guangdong, they went back and retested 320,000 samples originally taken for influenza surveillance and other screening . Lessthan 0.5 percent came up positive, which is about the same number as the 1,500 known Covid cases in the province . (Covid-19 is the medical name of the illness caused by the coronavirus.) There is no evidence that we' re seeing only t he tip of a grand iceberg, with nine-tenths of it made up of hidden zombies shedding virus. What we're seeing is a pyram id: most of it is aboveground. Once we can test anti bodies in a bunch of people, maybe I'll be saying, "Guess what? Those data didn't tell us the story ." But the data we have now don't support it. That 's good, if there' s little asymptomatic tr ansmission . But it's bad in that it implies that th e death rate s we 've seen - from 0.7 percent in parts of China to 5.8 percent in Wuhan - are correct, right? I've heard it said that "t he mortali t y rate is not so bad because the re are actua lly way more mild cases." Sorry - t he same number of people th at were dying, still die. The real case fatality rate is probably what it is outside Hubei Province, somewhere between 1 and 2 percent. Patients wait ing t o be t ransferred from one hospital in Wuhan to Leishenshan Hospit al, a newly bui lt medical center to address th e epi demic t hat is also in Wuhan, China.Credit ...Agence France-Presse Getty Images NIH-000916 What about children? We know they are rarely hospitalized . But do they get infected? Do they infect their families? We don't know. That Guangdong survey also turned up almost no one under 20. Kids got flu , but not this. We have to do more studies to see if they get it and aren't affected, and if they pass it to family members . But I asked dozens of doctors : Have you seen a chain of transmission where a child was the index case? The answer was no. Why? There's a theory that youngsters get the four known mild coronaviruses so often that they ' re protected. That's still a theory. I couldn't get enough people to agree to put it in t he W.H.O. report . Does that imply that closing schools is pointle ss? No. That's still a question mark . If a disease is dangerous, and you see clusters, you have to close schools. We know that causes problems, because as soon as you send kids home, half your wor k force has to stay home to take care of them. But you don't take chances with children . Are the cases in China really going down? I know there ' s suspicion, but at every testing clinic we went to, people would say, "It's not like it was three weeks ago." It peaked at 46,000 people asking for tests a day; when we left, it was 13,000. Hospitals had empty beds. I didn't see anything that suggested manipulation of numbers. A rapidly escalating outbreak has plateaued, and come down faster than would have been expected . Back of the envelope, it's hundreds of thousands of people in China that did not get Covid-19 because of this aggressive response. Is the virus infecting almost everyone, as you would expect a novel flu to? No - 75 to 80 percent of all clusters are in families. You get the odd ones in hospitals or restaurants or pr isons, but the vast majority are in families. And only 5 to 15 percent of your close contacts develop disease. So they try to isolate you from your relatives as quickly as possible, and find everyone you had contact with in 48 hours before that. You said differ e nt cities responded differently. How? It depended on whether they had zero cases, sporadic ones, clusters or widespread transmission. First, you have to make sure everyone knows the basics: hand-washing, masks, not shaking hands, what the symptoms are. Then, to find sporadic cases, they do fever checks everywhere, even stopping cars on highways to check everyone. As soon as you find clusters, you shut schools, theaters, restaurants. Only Wuhan and the cities near it went into total lockdown. How did the Chinese reorganize their medical response? First, they moved 50 percent of all medical care on line so people didn't come in. Have you ever tried to reach your doctor on Friday night? Instead, you contacted one online. If you needed prescriptions like insulin or heart medications, they could prescribe and deliver it. NIH-000917 Grocery delivery to a quarantine area in Wuhan, China.Credit ...Agence France-Presse - Getty Images But if you thought you had coronavirus? You would be sent to a fever clinic. They would take your temperature, your symptoms, medical histo ry, ask where you'd traveled, your contact with anyone infected. They'd whip you through a CT scan ... Wait - "whip you through a CT scan"? Each machine did maybe 200 a day. Five, 10 minutes a scan. Maybe even partial scans. A typical hospital in the West does one or two an hour. And not X-rays; they could come up normal , but a CT would show the "ground-glass opacities" they were look ing for . (Dr. Aylward was referring to lung abnormalities seen in coronavirus patients .) And then? If you were still a suspect case, you'd get swabbed. But a lot would be told , "You' re not Covid." People would come in with colds, flu, runny noses. That's not Covid. If you look at the symptoms, 90 percent have fever, 70 percent have dry coughs, 30 percent have malaise, trouble breathing. Runny noses were only 4 percent. The swab wa s for a PCRtest , right? How fast could they do that? Until recently , we w ere sending all of ours to Atlanta. They got it down to four hours . So people weren't sent home? No, they had to wait . You don't want someone wandering around spreading virus. If they were positive, what happened ? They'd be isolated. In Wuhan, in the beginning, it was 15 days from getting sick to hospitalization . They got it down to two days from symptoms to isolation . That meant a lot fewer infected - you choke off this th ing's ability to find susceptibles . What' s the difference between isolation and hospitalization? NIH-000918 With mild symptoms, you go to an isolation center. They were set up in gymnasiums, stadiums - up to 1,000 beds. But if you were severe or critical, you'd go straight to hospitals. Anyone with other illnesses or over age 65 would also go straight to hospitals. What were mild, severe and critical? We think of "mild" as like a minor cold. No. "Mild" was a positive test, fever, cough - maybe even pneumonia, but not needing oxygen. "Severe" was breathing rate up and oxygen saturation down, so needing oxygen or a ventilator. "Critical" was respiratory failure or multi-organ failure. So saying 80 percent of all cases are mild doesn't mean what we thought . I'm Canadian. This is the Wayne Gretzky of viruses - people didn't think it was big enough or fast enough to have the im pact it does. A sports stadium converted to a makeshift hospital in Wuhan, China.Credit...China Daily/Reuters Hospitals were also separated? Yes. The best hospitals were designated just for Covid, severe and critical. All elective surgeries were postponed. Patients were moved . Other hospitals were designated just for routine care: women still have to give birth, people still suffer trauma and heart attacks. They built two new hospitals, and they rebuilt hospit als. If you had a long ward, they'd build a wall at the end with a window, so it was an isolation ward with "d irty" and "clean" zones. You'd go in, gown up, treat patients, and then go out the other way and de-gown . It was like an Ebola treatment unit, but without as much disinfection because it's not body flu ids. How good were the severe and critical care? China is really good at keeping people alive. Its hospitals looked better than some I see here in Switzerland. We'd ask, "How many ventilators do you have?" They'd say "50 ." Wow! We'd say, "How many ECMOs?" They'd say "five ." The team member from the Robert Koch Institute said, "Five? In Germany, you get three, maybe. And just in Berlin." NIH-000919 (ECMOs are extracorporeal membrane oxygenation machines, which oxygenate the blood when the lungs fail.) Who paid for all of thi s? The governmen t made it clear: testing is free. And if it was Covid-19, when your insurance ended, the state picked up everything . In the U.S., that's a barrier to speed. People think: "If I see my doctor, it's going to cost me $100. If I end up in the I.C.U., what's it going to cost me?" That'll kill you. That's what could wreak havoc. This is where universal health care coverage and security intersect. The U.S. has to think t his through. What about the nonmedical response? It was nationwide. There was th is t remendous sense of, " We've got to help Wuhan ," not "Wuhan got us into this." Other prov inces sent 40,000 medical workers, many of whom volunteered . In Wuhan, our special train pulled in at night, and it was the saddest thing - the big intercity tra ins roar right through, with the blinds down . We got off, and another group did. I said, "Hang on a minute, I thought we were the only ones allowed to get off ." They had these little jackets and a flag - it was a medical team from Guangdong coming in to help . How did people in Wuhan eat if they had to stay indoors? Fifteen million people had to order food on line. It was delivered. Yes, there were some screw-ups. But one woman said to me: "Every now and again there's something missing from a package, but I haven't lost any weight ." A yoga class being taught on line from a studio in Beijing.Credit ...Roman Pilipey/EPA, v ia Shutterstock Lots of gove rnm ent employ ees w ere reassigne d? From all over society . A highway worker might take temperatures, deliver f ood or become a contact tracer. In one hospital, I met the woman teaching people how to gown up. I asked, "You're the infection control expert?" No, she was a receptionist. She'd learned . NIH-000920 How did technology play a role? They're managing massive amounts of data, because they're trying to trace every contact of 70,000 cases. When they closed the schools, really, just the buildings closed. The schooling moved on line. Contact tracers had on-screen forms . If you made a mistake, it flashed yellow. It was idiot -proof. We went to Sichuan, which is vast but rural. They'd rolled out SG. We were in the capital, at an emergency center with huge screens. They had a problem understanding one cluster. On one screen, they got the county headquarte rs. Still didn't solve it. So they got the field team. Here's this poor team leader 500 kilometers away, and he gets a video call on his phone, and it's the governor. What about social media? They had Weibo and Tencent and WeChat giving out accurate informat ion to all users. You could have Facebook and Twitter and lnstagram do that. Isn't all of this impossible in America? Look, journalists are always saying: "We ll, we can't do this in our country." There has to be a shift in mind-set to rapid response thinking . Are you just going to throw up your hands? There's a real moral hazard in that, a judgment call on what you think of your vu lnerable popul ations. Ask yourself: Can you do the easy stuff? Can you isolate 100 patients? Can you trace 1,000 contacts? If you don't, this will roar through a community . Isn't it possibleonly because China is an autocracy? Journalists also say, "We ll, they're on ly acting out of fear of the government," as if it's some evil fi rebreathing regime that eats babies. I ta lked to lots of people outside the system - in hotels, on trains, in the streets at night . They're mobilized, like in a war , and it's fear of the virus that was driving them. They really saw themse lves as on t he front lines of protecting the rest of China. And the world. NIH-000921 A medical worker in a hospital in Wuhan working with traditional medicines to treat patients.Credit ...Agence France-Presse - Getty Images China is restarting its economy now. How can it do that without creating a new wave of infections? It's a "phased restart ." It means different things in different provinces . Some are keeping schools closed longer. Some are only letting factories that make things crucial to the supply chain open . For migrant workers who went home - well, Chengdu has 5 million migrant workers. First, you have to see a doctor and get a certificate that you're "no risk." It's good for three days. Then you take the train to where you work. If it's Beijing, you then have to self-quarantine for two weeks. Your temperature is monitored, sometimes by phone, sometimes by physical check. What's going on with the tr eatment clinical tri als? They're double-blind trials, so I don't know the results. We should know more in a couple of weeks. The biggest challenge was enrolling people. The number of severe patients is dropping, and the re's competition for them. And every ward is run by a team from anothe r province, so you have to negotiate with each one, make sure they're doing the protocols right . And there are 200 trials registered - too many. I told them: "You've got to prioritize things that have promising antiviral properties." And they're te sting traditional medicines? Yes, but it's a few standard formulations. It's not some guy sitting at the end of the bed cooking up herbs. They think they have some fever -reducing or anti -inflammatory properties. Not antivirals, but it makes people feel better because they're used to it. What did you do to protect yourself? A heap of hand-sanitizer. We wore masks, because it was government policy. We didn't meet patients or contacts of patients or go into hospital dirty zones. And we were socially distant. We sat one per row on the bus. We ate meals in our hotel rooms or else one person per table. In conference rooms, we sat one per table and used microphones or shouted at each other. That's why I'm so hoarse. But I was tested, and I know I don't have Covid. NIH-000922 Dr. Aylward offered an elbow in lieu of a handshake during a briefing in Geneva on the W.H.O. mission to China.Credit.. .Salvatore Di Nolfi/EPA, via Shutterstock Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH, HHS , or the U.S. government. NIH-000923 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 12:31:28 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Nicolle Wallace/ MS NBC interview request for today or next week ... FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robinson, Querry (NBCUniversal) Date: Friday, March 6, 2020 7:17 AM To: Conrad, Patricia (NIH/NIA ID) [E) (b)(6); Fauci, Anthony (NIH/NIAID) [El (b) ( > Subject: Nicolle Wallace/ MSNBC interview request for today or next week ... ---------=-=-= Hi Patricia, This is Querry Robinson with Nicolle Wallace at MSNBC's 'Deadline: White House' in New York again. I am writing to request an interview with Dr. Fauci today during the 4 pm ETor at some point next week if his schedule may allow. Nicolle is hoping to speak with Dr. Fauci about growing concerns over the spread coronavirus and what the public should be doing now in the wake of this pandemic . We would gladly have Dr. Fauci join us from the NIH camera if his schedule may allow .. Please let me know if today may be a possibility or if another day next week may be better for the schedule when you may have a moment. All the best, NIH-000924 Querry Quer ry Robinson 'Deadline: White House' with Nicolle Wallace 30 Rockefeller Plaza, NY, NY 10112 W - 212-664 -3923 C- (b)(6) querry .robinson@ nbcuni.com Sent from my iPhone - please overlook any misspellings or grammatical errors NIH-000925 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:02:56 +0000 To: Cassetti, Cristina (NIH/ NIAID) [El Subject: FW: Emergency Preparedness , Coronavirus , and Products from MPI Attachments : MPI - CloroxPro_Scrubs_2019 (1).pdf, MPI - Cloro xPro_LabCoats_2019.pdf, MPI - PrimeMedical _Curtains_Flyer.pdf, MPI - POW_HOSP_Barrier_Protection_28update29.pdf, MP I EvaClean Tri Fold 2019 .pdf Please take a look and handle if necessary From: Brad W icklas (b)(6 )> Date: Friday, March 6, 2020 3:46 AM -------=:-:-=, To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Emergency Prepared ness, Coronavirus, and Products from MPI Hi Anthony F auci, I know you're busy, but I wanted to introduce our Company, Medical Partners Internation al, and talk for a quick minut e about what we do and how it can help you. As you know, the CDC has asked all healthcare facilitie s to prepare for the "worst case scenario" around the Novel Coron avirus. As much of our medical supply manufacturing in the US comes from overseas , it is of critical import to look at potential shortages of key product s that will be needed to perform basic IP functions in you r facility . We have already seen challen ges with N95 masks, and I have heard about potential shortag es of items like disinfect ion wipes . We at MPI have a couple of uniqu e solution s you need to consider: PureTabs and PureOne NaDCC tablets that are diluted in tap water to create HOCl for surface disinfection. They are currently used in electrostatic spraye rs to offer greater coverage around your equipme nt. If, for some reason , there's a challenge getting the electrostati c spray ers in the future (and we've already seen shortages and delays in getting new units), simpl y use our NaDCC tablets with spray bottle s from your local store to apply the HOCl for disinfe ction. Our tablets have kill claim s for C. diff in four minutes, and like a number of other cleaning agents , we believe we can be effectiv e against the Novel Coronaviru s. The prob lem with the other products out there comes down to availability, particularly of the N95 masks that are required on their IFU's. With our product, an N95 mask is recommended, but not required, which is a huge distincti on if you have run out of N95 masks. Secondly , we have our protective scrub s, lab coats and privacy curtains from Prime Med ical. Co-branded with Clorox, these products create a 3 log (99.9%) barrier against bacteria and viruses when washed with bleach. The barrier lasts for 12 weeks, NIH-000926 so there's a dramatically lower chance of passing something along. These are a great protective measure for your staff. The CDC mentioned that sodium hypochlorite (bleach) may be effective against Novel Coronavirus, so it stands to reason that our scrubs will help against unwanted spreading as well. Finally, we have our Path-0-Wrap, which protects mattresses and gurneys from the harsh chemicals used during cleaning. It also can help dramatically when a catastrophic event happens, as you simply put these on a gurney or mattress and remove them between patients. It was invented by an EMT for just this purpose , and may be exactly what you need for your Emergency Preparedness Program. We also have other great IP products such as: • UV Disinfection Boxes to create a "touch-less check-in" to protect staff and patients alike • HealthySo le UV solutions for the bottom of feet for OR and other sensitive areas • Bowman Cover Your Cough Stations I have attached a couple of brochures for your review. We can provide you with a quote, or have our local representative bring in samples of some of the products to show. Simply write me back with what you would like more information on. We feel our products will make a difference for your facility; let us know how we can help. Sincerely , Medical Partners International Brad Wicklas Managing Partner Cell: CbH6) Websi te: www .bwicklas @medpint.com NIH-000927 Medical Partners lnt'I NIH-000928 From: Date: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 11:00:51 +0000 Corey MD, Larry;Dieffenbach, Carl (NIH/NIAID) [El RE:coronovirus vaccine testing To: Subject: Anything that works is fine with me. From: Corey MD, Larry Date: Friday, Ma rch 6, 2020 12:23 AM To: Dieffenbach, Carl (NIH/NIAID) [E) (b)( 6) > (b)(6)> ----------------- r,a-s-,~ (b)(6); Fauci, Anthony (NIH/NIAID) [E) Subject: coronovirus vaccine testing I know the VTEU's are first in line but I am sure th e HVTN sites would be quite willing to participate in any coronavirus vaccine testing and if you need international populations the sub Saharan African sites will I am sure be interested . so our informal polling of sites revealed enthusiasm. NIH-000929 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 04:07:20 +0000 Cassetti, Cristina (NIH/NIA ID) [El FW: SARSCoV entry inhibition for the masses Novel Inhib itors of SARSCoV Entry .pdf Please handle. Chris So rg (b)(6)> Date: Wednesday, March 4, 2020 4:24 PM To: Fauci, An th ony (NIH/ NIAID) [E] -----From: --=(b=)(=6) Subject: FW: SARScov entry inhibition for the masses Dear Dr. Fauci: I really think you should look at thi s emai l trail. I can't seem to (b) (4) NIH-000930 Respectf u Ily, John C. Sorg, M.D. Cell: (b)(6) Chris Sorg Hospit alist Nor th A rkan sas Region al Medical Ce nt er 620 North Main Str eet, Ha r rison, AR 72601 Offic e: ...__ ....:--" ....-.il ....... NORTH ARKANSAS ~ RfG lONAL MI D I OAL ClNfU'I OR'S ~~4~;f;y Award From: Chris Sorg Date: Monday, Ma rch 2, 2020 1:16 PM To: (b)(6) Subject: FW: SARSCoV entry inhibition for the masses Continuing to think outloud. (b) (4) J.C. Sorg, M. D. Chris Sorg H ospit alist Nor th Arkan sas Regional Medical Ce nt er 620 Nor t h Main Str eet, Harri son, AR 72601 NIH-000931 Office : (b) ( NORTH ARKANSAS ~ ....-.il ~ REGlONAL • • u, c AL c •" GOVERNOR'S QualityAward T• R From: Chris Sorg Date: Monday, March 2, 2020 12:11 PM To: (b) (6) Cc: Subject: SARSCoV entry inhibition for the masses -------------------------------- (b)(6) (b) (4) RespectfullyJ J.C. SorgJ M. D. Internal Medicine Chris Sorg Hospitalist North Arkansas Regional Med.icalCenter 620 North Main Street , Harrison , AR 72601 Office (b) (6) ' NORTH ARKANSAS~ ~ REGlONAL GOYEROR'S ....-.il .. ■ DI c• i. c • QualityAward 11 T • R Confidenlialit~ ~olic~: I hi- 1:111,111 nnd lll\ l1k, lransn1111~Jw1•h 11,, Th" n.upl\.:llt \ r11i.~ JlilUl"JlldtH.lll c-,11fak1nal ~ H:(JUIJ\ ..J In 111J1111<11d,dsC1kl\ hH !he 11·,~t•l lh, 1•1d1,1d11,ilor~ 1111 \ r,11,hem lite\ ir, 1d) 1h..:rnJo,m...ilh.JII ,t.lh.·1ll~ !\l,1,1..·tJ 1-.;~J ha-. bc..:n lullt,lctl 1J )UU Jll 11111lhl JJ1ll..:nJ1..·d 1~up11-..·1u t• I ~n .. 1111-.,101 1J1 ,lit ·111rlny·c H :H• 1\1 ti.:,pn11,1hl1.. I lrdch\.•flllt 11u...1r:llhll11,,1n111., 1h...111h...·11d ....o FL•up1e111 \01111111,11ml IL\I \ rdru1,n11t ..:<1nvcr1h• 1 r<, u•p\ u>p~ uru,e 1h1~ lrs1sn is,1,111, r Jlll a11,11.n111,111' lr.ltNnllttd \\1lh111 lf",u 1.1,~ r~~cl\ed 1hi- rtln,1111s,11111 •~ c1Tc,rlti, c ,,m prcblcni~ l\'tlh •his ll"m<1111 To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Robert Chen Subject: Meeting to AssessEvaluation of COVID-19 vaccine candidates for risk of enhanced disease Dear Doctor Fauci, I am writing to you as a member of the SPEACproject which CEPI has funded to assist with the evaluation of the safety of vaccines in their portfolio. As part of this effort, we are assisting with developing preclinical and clinical test ing criteria to evaluate the risk of enhanced disease fol lowing vaccination with COVID-19 vaccine candidates. As you know, this had been an issue with some prior SARSvaccine candidates. We are convening a two day virtual meeting of experts via video conference next week on March 12 and 13 between 8 am and 1 pm Eastern ti me each day. Participants in the meeting are shown in the attached agenda but include Paul Henri Lambert from Geneva and Barney Graham from NIH. The meeting will actively involve the participants on the agenda the first day and on the second day the meeting will be open for several peer reviewers including Stanley Plotk in and Andy Pollard to review and comment on possible small and NHP animal models as well as appropriate immunologic testing to be done in early phase one trials. I am wanted to make you aware of the meeting so that you could attend all or part as an observer if you wish but also to invite you to consider joining on day two as one of our formal peer reviewers. The goal of the meet ing would be to share recommendations with CEPI COVID-19 developers as well as other interested part ies. Any comments you have on the agenda or draft questions for consideration would be greatly appreciated. I look forward to hearing back from you. ATTACHMENTS: DRAFTAGENDA; DRAFTQUESTIONSFORCONSIDERATION NIH-000933 Steve Steven Black MD SPEACProject work package lead for CEPI NIH-000934 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:04:44 +0000 00~ Subject: FW: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients To: fyi From: Folkers, Greg {NIH/NIA ID) [E) Cb)( > Se nt: Wednesday, Marc h 4, 2020 4:27 PM Subject: medRxiv: Detectable serum SARS-CoV-2viral load (RNAaemia) is closely associated w ith drastically elevated inte rleu kin 6 (IL-6) level in critically ill COVID-19 patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely associated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Xiaohua Chen, Binghong Zhao, Yueming Qu, Yurou Chen, Jie Xiong, Yong Feng, Dong Men, Qianchuan Huang, Ying Liu, Bo Yang, Jinya Ding, Feng Li doi: ht t ps://doi .org/10 .1101/2020.02 .29.20029 520 This article is a preprint and hasnot been peer-reviewed [what doesthis mean?]. It reports new medicalresearchthat hasyet to be evaluatedand so shouldnot be usedto guide clinical practice . • Abstract • Info/ History • Metr ics • • Preview PDF Abstract Background: Although the SARS-CoV-2 vira l load detection of respiratory specimen has been widely used for novel coronavirus disease (COVID-19) diagnosis, it is undeniable that serum SARS-CoV-2nucleic acid (RNAaemia) could be detected in a fraction of the COVI0-19 patients. However, it is not clear that if the incidence of RNAaemia could be correlated with th e occurrence of cytokine storm or with the specific class of patients. Methods: This study enrolled 48 patients with COVID- 19 admitted to the General Hospita l of Central Theater Command, PLA,a designated hospital in Wuhan, China. The patients were divided into three groups according to the Diagnosis and Treatmen t of New Coronavirus Pneumonia (version 6) published by the Natio nal Health Commission of China. The clinical and laboratory data were collected . The serum viral load detection and serum IL-6 levels were determined. Except for routine statistical analysis, Generalized Linear Models (GLMs) analysis was used to establish a patient status NIH-000935 prediction model based on real-time RT-PCRCt value . Findings: The Result showed that cases with RNAaemia were exclusively confirmed in critically ill patients group and appeared to reflect the illness severity. Further more, the inflammatory cytokine IL-6 levels were significantly elevated in critically ill patients, which is almost 10-folds higher than those in other patients. More importantly, the extremely high IL-6 level was closely correlated with the incidence of RNAaemia (R=0.902) and the vital signs of COVID-19 patients (R= -0.682). Interpretation : Serum SARS-CoV-2 viral load (RNAaemia) is strongly associated with cytokine storm and can be used to predict the poor prognosis of COVID-19 patients. Moreover, our results strongly suggest that cytokine IL-6 should be considered as a therapeut ic target in critically ill patients with excessive inflammatory response. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTAID, NTH, HHS, or the U.S. government. NIH-000936 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:01:59 +0000 James Krellenstein RE:2019-nCo\/ Testing fo r Public Health Labs James: Thanks for the note. Be ass.~red that I am trying to break this log jam. Best, Tony From: James Krellensteih sent: Wednesday, March 4, 2020 6:46 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) _.,, (b.,.. )(=6) Subject: Re: 2019-nCoV Testing for Public Health Labs Tony: I am loath to contact you give n that I am sure you are overwhelmed . However, we are now being contacted by sources at tertiary academic hospita ls with CUA-high complexity clinical labs who are alarmed about their inability to scale up SARS-CoV2 qRT-PCRtesting in t heir facilities in the time frame they feel is neccesary, even after Saturday's FDA regulatory guidance and the availability of Integrated DNA Technology 's testing reagents. (An example of such an email is below.) I am passing th is along with the hopes that if you can do something about it , you will. From an email: "We have experience bringing up laboratory deve loped tests. We have never submitted an EUA before. For our current LDTs, they are typically for pathogens that we have some experience with, positiv e clinical samples are readily available, and/or appropriate control materials (e.g. bact eria, viral genomes) are read ily commerc ially available. None of those are true for SARS-Co V2. There is tremendous concern about deploying a suboptima l test into a challenging envirom11ent. The EUA guidance from FDA is not unreasonable for the validation of a new respiratory virus test, and it gives an accurate picture of the amount of testing that is required to bring on a new test by the lab. Federal law requires us to perform accuracy , reproducib ility, analytica l sensitivity / LOD, and analyt ical specificity (cross reactivity) studies. Those stud ies require pos itive contro l mater ial includingintact v irus or RNA. Clinica l labs are not prepared to generate RNA transcript , and we don't usually source these ourselves. We can't get the virus without filling out extensive paperwork that requires multiple signatures. Getting control material for validation one of the biggest issues . NIH-000949 Prior to the EUA change, the calculus for our labs was that it would take 3 to 4 weeks to actually validate a test, and then we would submit to the FDA for EUA (a process non e of us has ever done), and then we wou ld wait for the FDA to respond (hopefu lly in the affirmative). I think we all expected the FDA EUA review to be at least 4 weeks. Based on that time-line, many commercial vendors would have reagents available with their own EUAs that would be able to be performed on large automated instruments including potentially STAT. None of the LDT assays (or CDC assay) can be performed STAT or on demand. With the EUA change, the proc ess to va lidate the test is st ill the same and will still take 3 or more weeks. Once validated, we can perform clinical testing (like any other LDT) while we submit the EUA. This would likely allow us to begin testing several weeks before commercial vendors have EUA reagents available based upon our best current infonnation. Most of us expect to transition a commercial EUA at some point. The recent statement that IDT reage nts can be used under the EUA from CDC is misleading. It applies to a very limited number of lots ( cunently 1, likely 2 soon), it assumes reagents are available, and it requires strict adherence to the CDC protocol using identical extraction methods (2 choices) and amplification/ detection methods ( l instrument). It still specifies the use of an Nl, N2, and NJ reactions, but CDC has dropped the N3 reaction . The EUA has not yet been updated. Neither of our hospitals have the complete extract ion or amplifi cation instruments so we have to do the EUA anyway." Hope you are coping ok, James James 8. Krellenstein 109 S 5th St, Brooklyn, NY11249 (b)(6) (mobile) (b)(6) On Sun, Feb 2, 2020 at 7:36 PM James Krellenstein --------- (b)( > wrote: Tony: I hope this email finds you well. Over the past 48 hours, PrEP4AIIhas received multiple requests from leaders of public health departments and public healt h practitioners to begin publicly pressuring NIH-000950 CDC/HHSto ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcr iption PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019nCoV). Our understa nd ing is that given the public health emergency declared by HHS, an emergency use aut horization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotoco l and primer/probe sequences ( https://www.cdc .gov/coronav irus/20 19-ncov/down loads/rt -pcr-panel-for -detection -instruct ions.pdf ) , and the lab is capable of handling BSL3+samples. We understand the extreme delicateness of this situation, and also that it is outside of our normal wheelhouse. But given the concerns of our colleagues in the public health sector, we thought it wa s important to give you a heads up regard ing this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AIICollaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) James B. Krellenstein he- him - his (b)(6) (Sent from a mobile device) NIH-00095 1 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 04:00:31 +0000 (b)(6) To: Subject: Attac hment s: FW: Covid-19 causes CRS(and source of mortality) Ruan2020_A rticle_ Clinical PredictorsOfMorta lityD. pdf FYI -------- From: Pavletic, Steven (NIH/NCI) [E) (b)(6)> Se nt: Wednesday, March 4, 2020 10:18 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: Covid-19 causes CRS(and source of mortality) ------~~ -------- Dear Dr Fauci, this is not an area of my expertise, but given the urgency of situat ion with the Covid-19 and some of our experiences with treating CARTinduced cytokine release syndrome in cancer patients, just wanted to share this email with you in case you find it of interest . Dr Betts is my brilliant junior BMT colleague at University of Minnesota. I realize this may be old news to you but wanted to share just in case. Warm regards Steve Pavletic From: Brian Betts (b)(6)> Date: Wednesday, Marc h 4, 2020 2:06 PM To: Pavletic, Steven (NIH/NCI) [E] (b)(6)> Subject: Covid-19 causes CRS(and source of mortality) ------ --~ Hi Steve, This is an interesting paper from intensivists in Wuhan. The IF of the journal is 18 too . Looks like covid-19 causes an IL-6 mediated CRSwith myocarditis, which is associated with mortality (more so than the pneumonitis) . This suggests we should be more concerned with getting tocilizumab for critically ill covid-19 pat ients, rather than tam iflu and ARVT... Do you have a friend at the CDCthat could use this info? Thanks, Brian BrianC. Betts MO Associate Professorof Medicine Division of Hematology, Oncology and Transplantation University of Minnesota NIH-000952 The infor mation transm itte d in this e-mai l is intended only for the per son or entity to which it is addressed and may conta in confidential and/or privileged material, Including "protected healt h informa tion ." If you are not th e inten ded recipient, you are hereby notified that any review, retransmission, dissem inat ion, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please destroy and delete th is message from any computer and contact us immed iately by return e-mail. NIH-000953 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 6 Mar 2020 03:57:38 +0000 Conrad, Patricia (NIH/NIAID) [E);Greg Folkers (b)(6) FW: COVID-19 event Friday @CSISTony March 20, 1:30pm-3:30pm Date: To: Subject: Let us discuss. From: Stephen Morrison Se nt : Thursday, March 5, 2020 7:02 AM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Samantha Stroman Subject: Re: COVID-19 event Friday @CSISTony March 20, 1:30pm-3 :30pm --------- Hi Tony Will March 20 work for you? Best Steve On Mar 2, 2020, at 10:07 AM, Stephen Morrison wrote: Tony I know the demands on you have skyrocketed, so I am circling back to confirm you are still available on Friday March 20 for the COVID-19 event, and also to seek your advice, as we amend the layout of the event, including possibly havi ng it run a little longer . I am still hoping you can do a big picture scene sette r {15-20 minutes with slides) (i) (ii) (iii) (iv) The state of the science surrou nding the virus, what we know and do not know, Progression of the outbreak Testing Status of accelerated early work on vaccines, antivirals We wi ll have a panel that covers China, and we may add a panel on the epicenters in Italy, ROK,Iran I would like to carve out ample space for discussion of the United States. In your view, is it advisable to put a request forward to Secy Azar or VP Pence? Neithe r needs a platform to have thei r voices heard. But perhaps they would see this sort of sett ing as an opportunity. If not the Secy or VP, is there anyone else you might propose? I had reached out earlier to Steve Biegun to speak on the foreign policy dimensions, especially regarding China, but have not heard back. I have separately reached out to the NGA about possibly enlisting a governor to speak. NIH-000954 If you are free and wish to speak by phone about any of this, please let me know. Best of luck with everything. You seem to be making progress! Best Steve ----- Cell (b)(6) NIH-000955 From: Date: F.aucl,Anthony (NIH/NIAID) [El Fri, 6 Mar 2020 03:56:47 +0000 MAVILIO Domenico ICH RE:Ciao To: Subject: Domenico: Thanks for the note. Indeed, this outbreak has changed the lives of many people, including me. I am doing nothing else but coronavirus. I cannot predict when the travel restriction for Northern Ita ly will be removed. I hope soon, but I doubt that. STAY WELL. Best regards, Tony -------------------::-::-:-= From: MAVILIO Domenico ICH (b)(6) Date: Thursday, March 5, 2020 7:49 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Ciao -------- (b)(6)> Hi Tony, ju st a short notice to tell you that you are becoming even more popular in Italy as your face and interviews are everywhere on the main Italian broadcasting news and journals . It seems like to be in USA again for me, as I see you every day and I can tell you are doing well although you must be overwhelmed with all this. I was supposed to be at NIH in tre weeks from now , but I have cancelled the flight and travel due to highest restrictions from CDCand HHSfor Italian travellers from Lombardia and Veneto (and I live in Milan). Can we estimate how long all this w ill last? Weeks or months according to you knowledge? Hope to see you soon anyway and I really hope U.S. outbreak will not turn as bad as the Ita lian one. Indeed, Milan is living a real unprecedented (for modern t ime) and surrealistic situati on with a mix of fear, panic and incredulity among people. It almost seems a movie! The government shut down half country by closing all schools and universities, by not allowing meetings of any kind, by limi t ing travels in many places and by placing severe restrictions in social life. They even stopped the Fashion week in Milan that is a big thing here. Maybe too late, but they didi it and we hope it will work somehow to reach a plateau in contagious. have a nice day Ciao Domenico Domenico Mavilio, M.D., Ph.D. Associate Professor of Translational Medicine NIH-000956 Department of Medical Biotechnologies and Translational Medicine Medical School of Milan University , Milan, Italy Principal Investigator Head, Unit of Clinical and Experimental Immunology Humanitas Research Hospital, Rozzano, Mi lan, Italy Adjunct Investigator Laboratory of Cardiovascular Regenerative Medicine, Nationa l Hearth , Lung and Blood Institute Nationa l Institutes of Health, Bet hesda, MD, USA (b)(6) Phone: (b)(6) Fax: +39 02 8224 5191 emai ls: .J========= (b)(6) (b~ )(=6X (b)(6) webpage: http ://www .huma nitas-research.org/ category/p ri nci paI-investi gat or/mav il io/ h m Y NIH-000957 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 03:51:21 +0000 Phillips, Kyra Conrad, Patricia (NIH/NIAID) [El RE: Hi Tony ! Univ of Nebraska ..... Kyra: Thank s for the note. You would .have to go through my Special Assistant, Patty Conrad, who is copied on this email. Best, Tony ----- Original Message- ---From: Phillips , Kyra Date: Thursday, March 5, 2020 9:30 AM To: Fauci , Anthony (NTH/NIAJD) [E] Su~ject: Re: Hi Tony! Univ of Nebraska ..... -------,:,,:-:= --------(b)( Good morning! I made contact and it's in the works! We even have them in our 20/20 spec ial tomorrow night! Question: do you think you could go live with me from NIH or WH one day next week for our Noon Coro navirus show? it 's live steamed so we have millions of viewers . We would take viewer questions (1 wo uld give you ahead of tim e) and you woul d answer only those you want to. I t's a half hour show , but we would do whatever amowlt of time your sched ule allows. It would be so impactful for the average viewer. V/R Kyra @KyraPhillips , ABC News Jnvestigative Correspondent KyraPhillips.Com (b)( (b) (6)> wrote: > On Mar 3, 2020, at 10:32 PM, Fauc i, Anthony (NTH/NJATD)[E] > > Kyra: > They very well mi ght let you do it. It is worth a try . The containment there is exce llent and there is no evidenc e ofcommuniLy spread in Omaha. > Best, > Tony > > -----Original Message----> From: Phillips , Kyra > Date: Tuesday, March 3, 2020 6:21 PM > To: Fauci, Anthony (Nlli/NIAID) (E] Cb)( > > Subject: Hi Ton y! Univ of Nebraska ..... > > Ton y, > Do you think the University of Nebraska would let me in to do a story for ABC News on the therapeutics they are working on? > Would it even be safe for me to do it? -------- ------~~ NIH-000958 > Appreciate how you are holding court during this crisis. > Respectfully , > Kyra > > > @KyraP hillips, ABC News > Investigative Corre spondent > KyraPhillips.Com > > (b) (6) NIH-000959 NIH-000688 From: Date: To: Subject: (b)(6) Tue, 10 Mar 2020 14:57:59 -0400 Short, Marc T. EOP/OVP Re: White House Coronavirus Task Force Meeting at **3:30pm** on 3/10/20 Marc: I likely will be severa l minutes late since 1 have to come down from Bethesda by Metro and the time change threw me off. Sorry. Tony ---------- > On Mar l 0, 2020 , at 2:49 PM, Short , Marc T. EOP/ OVP > > > NIH-000708 (b) (6) wrot e: NIH-0007 11 (bX5)-PCE NIH-0007 12 From: Date: To: Fauci,Anthony (NIH/NIAIO) [E) Tue, 10 Mar 2020 15:59:26 +0000 Hurst, Natalie R. EOP/OVP Cc: Subject: Mars ton, Hilary {NIH/NIAID) [E] RE: Important Updates - White House Coronavirus Subtask Force Calls Natalie: Please add my Assistant, Dr. Hilary Marston, to the list of invitees to the Subtask Force Calls. She reports directly to me and is my source of de-briefing after the calls. I am copying her on this e-mail. Many thanks. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail , (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Hurst, Natalie R. EOP/OVP (b)(6) Date: Tuesday, March 10, 2020 11:22 AM Subject: Important Updates - White House Coronavirus Subtask Force Calls Importance: High Good morning all, I wanted to send a n ote to clarify the White House Coronavirus Subtask Force Calls moving forward. There will be a Whit e House Coronavirus Subtask Force Call every day, unless otherwi se directed by Olivia Troye , Dr. Debi Birx, or me. • Monday - Friday, the call will take place at 9:00am • Saturday - Sunday, the call will take place at 10:00am Start ing this evening, I will send a new calenda r invite for the rem ainder of this week's calls (Wednesday , March 11 / Thursd ay, March 12 / Friday, March 13). On Friday, March 13, I will send a ca lendar invite for this weekend's calls (Saturd ay, March 14 & Sunday, March 15). NIH-000718 Looking ah ead • Invites for weekday calls will be sent on Sunday nights . • Invites for weekend calls will be sent on Friday nights. • Please note : Call-in numbers for Saturday & Sunday will be different from the number used Mondays - Fridays. ** If you would like to be removed from this distributio n list, please respond to this email before 5:00 pm ton ight, so that you will be removed starting Thursday morni ng.*" Please do not hesitate to reach out with any quest ions or concerns. Thank you, Natalie Hurst Operat ions Coordinator, White House Coronavirus Task Force Executive Assistant to the Chief of Staff The Office of the Vice Pres ident (b)(6) NIH-000719 (bX5) -PCP. NIH-000809 (b)(5) - PCP. NIH-000810 NIH-0008 11 NIH-000843 NIH-000844 NIH-000845 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 8 Mar 2020 01:38 :49 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: White House Coronavirus Task Force Meeting on 3.8.20 at 4:00pm To: Subject: I need WAVES, please. Thanks. ----------- From: Hurs t , Nat alie R. EOP/OV P (b)(6) Date: Saturday, March 7, 2020 8:30 PM Subject: Whi te House Coro navirus Task Force Meeting on 3.8.20 at 4:00pm Importance: High AllThere will be a White House Coronavirus Task Force Meeting on Sunday , March 8 th at 4:00 pm in the White House Situation Room. Agenda will be forthcoming . Thank you , Natalie Hurst Opera tions Coordinator, Wh ite House Coronaviru s Task Force Executive Assistant to the Chiefo f Staff Th e Office of th e Vice Pr es id ent (b)(6) NIH-000853 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:03:24 +0000 To: Greg Folkers (b)(6) Subject: Attachments : FW: 2020 03 03 SC POTUSNIH Roundtable. Email #1 P20200303SC-0059.jpg, P20200303SC-0066.jpg , P20200303SC-0088.jpg, P20200303SC-0109 .jpg, P20200303SC-0123.jpg, P20200303SC-0182.jpg, P20200303SC-0272.jpg For the fi le From: Hansen, Daniel E. EOP/WHO Date: Wednesday, March 4, 2020 6:36 PM (b)(6)> ----~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: FW: 2020 03 03 SC POTUS NIH Roundtable. Email #1 Photos from POTUS visit Tuesday NIH For Your Personal Archives 2020 03 03 SC POTUS NIH Roundtable. Email #1 P20200303SC 0088 President Donald J. Trump listens as Dr. Francis Collins, director of the National Institute of Allergy and Infectious Disea ses, addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0066 0109 NIH-000937 President Donald J. Trump participates in a coronavirus roundtable briefing Tuesday , March 3, 2020 , at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) P20200303SC 0059 0123 0182 President Donald J. Trump listens as Dr. Anthony S. Fauci, director of the National Institute of Health , addresses his remarks during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda , Md. (Official White House Photo by Shealah Craighead) P20200303SC 0272 President Donald J. Trump answers questions from reporters during a coronavirus roundtable briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Shealah Craighead) Please note that these photos are being sent to you for personal use only. If you share them with friends or family, make sure to include the disclaimer below. Thank you. If posting to social media the following byline must be used: Official White House Photo by Shealah Craighead This photograph is provided by THE WHITE HOUSEas a courtesy and may be printed by the subject(s) in the photograph for personal use NIH-000938 only. The photograph may not be manipulated in any way and may not otherwise be reproduced, disseminated or broadcast, without the written permission of the White House Photo Office. This photograph may not be used in any commercial or political materials , advertisements, emails, products, promotions that in any way suggests approval or endorsement of the President, the First Family, or the White House. Dan Hansen WH Photo Office NIH-000939 NIH-000940 NIH-000941 Fauci, Anthony (NIH/NIAID) [E) Fri, 6 Mar 2020 04:02:46 +0000 To: Greg Folkers (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle Attachments : P20200303JB-t34 7 .jpg, P20200303JB-1380.jpg, P20200303J8-1393.jpg, P20200303JB-1473.jpg, P20200303JB-1531.jpg, P20200303JB-1554.jpg, P20200303JB-1606.jpg, P20200303JB-1630.jpg, P20200303JB-1708.jpg, P20200303JB-1742.jpg From: Date: For the fi le From: Hansen, Daniel E. EOP/WHO (b)( > Date: Wednesday, March 4, 2020 6:42 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: FW: 2020.03.03 WH bSouth Lawn Arrival from NIH and Press gaggle -------=-:-= Subject: 2020.03.03 WH South Lawn Arrival and Press gaggle for Personal Archives P20200303JB-1347, 1380, 1393 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, disembarks Mar ine One on the South Lawn of the White House after attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at the Natio nal Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1473 President Donald J. Trump, joined by Dr. Anthony S. Fauci, director of the National Institute of Health, listens as Secretary of Health and Human Services Alex Azar answers a reporter's question following President Trump's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he Nation al Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1531, 1554, 1606 President Donald J. Trump, joined by Secretary of Health and Human Services Alex Azar, listens as Dr. Anthony S. Fauci, directo r of the National Institute of Healt h answers a reporter's question following President Trump 's return from attending a coronavirus roundtable briefing Tuesday, March 3, 2020, at t he National Institutes of Health in Bethesda, Md. (Official W hite House Photo by Joyce N. Boghosian) P20200303JB-1630,1708 President Donald J. Trump, jo ined by Dr. Anthony S. Fauci, director of the National Institute of Health, and Secretary of Health and Human Services Alex Azar, speaks with reporters following his return to the White House after attending a coronavirus roundtab le briefing Tuesday, March 3, 2020, at the National Institutes of Health in Bethesda, Md. (Official White House Photo by Joyce N. Boghosian) P20200303JB-1742 NIH-000942 President Donald J. Trump, Or. Anthony S. Fauci, director of the National Institute of Health , and Secretary of Health and Human Services Alex Azar, walk to the Oval Office Tuesday, March 3, 2020, at the White House. (Official White House Photo by Joyce N. Boghosian) Dan Hansen White House Photo Office (b)(6) NIH-000943 NIH-000944 NIH-000945 NIH-000946 NIH-000947 NIH-000948 (b)(6) From: Date: To: Cc: (NIH/NIAID) [E] Subject: Mon, 2 Mar 2020 08:32:20-0500 Tabak, Lawrence (NIH/OD) [E) Collins, Francis (NIH/OD) [E];Marston, Hilary (NIH/NIAID) [E];Conrad, Patricia Re: TIME SENSITIVE Larry: Let Hilary do this. I am on a conference call. Thanks , T ony On Mar 2, 2020 , at 8:27 AM, Tabak , Lawrence (N IH/OD) [E] Cb) (6)> wrote: TonyCould one of your folks give me a quick read out on this please? (should I reach out to Hilary Marston?) . This is the paper that DOE alluded to in the initial conference call we had with OSTP. I w ill respond informed by your staff's guidance. Larry From: "Mango, Pau l (HH S/10S)" Cb) (6J> Date: Monday , March 2, 2020 at 8: 19 AM To: Stephen Hahn CbH6J >, "Lenihan, Keagan (FDA/OC)" Cb)( >, Anthony Fauci Cb)( ·, "Tabak, Lawrence (NIH/OD) [E]" Cb> (6), "Redfield, Robert R. (CDC /OD)" CbH6) "McGowan, Robert (Ky le) (CDC /OD/OCS)" CbH6J >, "Berger, Sherri (CDC /OCOO /OD)" CbH> Cc: "Harrison, Brian (HHS /JOS)" Cb) <6J > Subject: T IME SEN SITIVE --------------- Dr Hahn and the FDA team in particular , but with input from relevant SMEs at CDC and NIH, please give the brief attached doctunent and quick read on comment on the usefulness of us sett ing up a sess ion with the folks at DOE today to discuss further . Many thanks Sent from my iPhone Begin forwarded me ssage: NIH-001047 From: ".Harrison, Bri an (HHS /1OS)" (b)(6) Date: Marc h 1, 2020 at 6:15:54 AM E ST To: CbH6J(OS /1OS)" CbH6J --~ Cc: "Steck er, Judy (OS/IOS)" (HHS/IOS)" Cb><> Subject: FW: ------- = (b)(6) , "Ma ngo, Pau l With attachment. I've asked CDC, FDA, NIH, and ASPRto review . From: Brouillette, Dan Date: Friday, February ---------28, 2020 9:58 PM To: Harrison, Brian (HHS/IOS)_______ (b)(6) ""' (b..,... H=6) Subject: Bria n: As we discussed earlier this evening, here 's a preliminary finding from scientists at Oak Ridge National Laboratory using the Summit supercompute r system. We stand ready to assi st in any manne r helpful to you and Secretary Azar. Very best, Dan Sent with Black.Berry Work (www.b lackberry .com ) NIH-001048 From: Date: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:15:02 +0000 To: Kadlec, Robert (OS/ASPR/IO);Redd, John (OS/ASPR/SPPR);Yeskey,Kevin (OS/ASPR/IO);Shuy, Bryan (OS/ASPR/IO);Phillips, Sally (OS/ASPR/SPPR) Cc: Redfield, Robert R. (CDC/OD) Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start We really need to discuss this. --------- (b)( > From: Kadlec, Robert (OS/ASPR/10) Date: Sunday, February 23, 2020 11:31 PM To: Redd, John (05/ASPR/SPPR)------~ (b~)(=, ; Yeskey, Kevin (OS/ASPR/10) (b)(6)>; Shuy, Bryan (OS/ASPR/10) (b)( ; Phillips, Sally (b)(6 b (OS/ASPR/SPPR) ----:---:---:-:.:==!--~ Cc: Redfield, Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) ------ Subject: Fwd: Red Dawn Breaking, CO\IID-19 Collaborative, Feb 16 start Read this! This is unsettling if true efficient spreading in asymptomatics with negative test . Is that possible? Report is intermittent shedding is that true or artifact of poor sample collection or lack of sensitivity of per testing? From Dr Eva Lee GaTech "Means of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-yea r old infected wi t h COVID-19 left Wuhan and went on infecting 5 relatives. When they tested positive, she was finally isolated , but tested negative still, and later tested positive , and remain normal on chest CT with no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because the re exists these very healt hy individuals who can spread effectively -- even during incubation per iod -- while they remain perfectly healthy . It also showcases difficulty in testing-- negative test -- may not be the end of it. " Sent from my iPhone NIH-001465 Begin forwarded message: From: "Dr. Eva K Lee" (b)(6)> Date: February 23, 2020 at 7:37:12 AM EST To: Carter Mecher (b)(6)> Cc: Richard Hatchett (b) (6)>, Tracey McNamara (b)( >, "Caneva, Duane" (b)(6), ...; (b ,.._., ~= c6)>, "Dodgen, Daniel (OS/ASPR/SPPR)" ==========::::...:... __ (b)(6)>, "DeBord, Kristin (OS/ASPR/SPPR) " -=======:::-:,:=:;:--------~~ (b)(6)>, "Phillips, Sally (OS/ASPR/SPPR)" (b)( >, (b)(6)>, "Hepburn, Matthew J CIV USARMY David Marcozz i (USA)" Will iam (STATE.GOV)" (b)(6)>, Lisa Koonin "Walters, (b)( (b)(6) , "HARVEY,MELISSA" (b)(6), "WOLFE, HERBERT" "Eastman, Alexander" (b)(6)>, (b)(6)>, "EVANS, MARIEFRED" (b)(6), "Callahan, Michael V.,M.D." (b)(6) >, "Johnson, Robert (OS/ASPR/BARDA)" __ -------.,;_..;___...;_ (b)(6)>, "Yeskey, Kevin" (b)(6), "Disbrow, Gary (b)(6)>, "Redd , Johnt(OS/ASPR/SPPR)" ~,::;;-""'.'.'"'---:-:--~-:-:--.-- >, "Hassell, David (Chris) (OS/ASPR/1O)" (b)(6) "Hamel , Joseph (OS/ASPR/1O)" (b)( >, "Dean, Charity A@CDPH" (b)(6)>, " Lawler , James V" (b)(6), "Kadlec, Robert (OS/ASPR/1O)" (b)(6) "' M artin, Gregory J (b)(6)>, "Borio , Luciana" (b)(6), "Hanfling, Dan" (b)(6) " McDonald, Eric" (b)(6) "Wade, David" (b)(6) (b)(6)>, "WI LKINSON, THOMAS" "TARANTINO, DAVID A" (b)(6)>, "David Gruber (b)(6) " ===========~c:;---7."."" (b)(6) , "KAUSHIK, SANGEETA" (b)( >, Nathaniel Hupert (b)(6)> Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Reply-To: "Dr . Eva K Lee" (b)(6)> ':':'"""--:-~--"'.-:.:========:~;-::-----,______ ... __ ___: :::...._ _~=====-:=~ --------~= """".'":'.~========:=;.~ A few things I want to highlight -1. M ea ns of spread A study from AMA confirmed many of the parameters assumed in our models: - A 20-year old infected with COVID-19 left Wu han and went on infecting 5 relatives. W hen they tested positive , she was fina lly isolated, but tes ted negative stil l, and later tested positive, and remain normal on chest CT wit h no fever, stomach or respiratory symptoms (cough or sore throat as late as Fen 11 (time of the papert study duration). So spreading and its wide scope is unavoidable because there exists these very healthy individuals who can spread effect ively -- even dur ing incubation period -- while they remain perfectly healthy. It also showcases difficulty in testing -- negative test -- may not be the end of it. NIH-001466 2. Iranian cases, though mysterious since the origin was not traced to China, may very well show that COVID-19 vi rus is very adaptable and mutating rapid ly. 3. Long recovery The long recovery period is troubesome and must be taken seriously by health providers as they prepare for hospitalization. Therei snot much surge capacity in hospitals. So they must be innoative in the staggering process and isolation is of paramount importance. Government/Local should be readied for supplementing medical tents outside hospit als when needed (clearly extra staff too) . 4. Citizes ' vi ew I was traveling so I did a real-time on-the-road analysis of human behavior and anxiety level. I overheard many people -- (a) asked when CDCwould tell us more on what to do. -- (b) wish t hey could pull their kids out of school but there is no such option as part of the preventive measure (not announced by CDC). -- (c) wish CDCwou ld recommend tele-work options so they don't have to travel and expose themselves and their family to unneccessary risk. -- (d) have no clue what the government is doing to keep the risk low as it is now. What exactly is being implemented to keep it low. 5. Resource -limit ed countri es I pray that it would not reach the resource-limited countries like many in Afri ca (though it seems unavoidable). I cannot imagine the consequence. 6. What we must do : We must leverage the knowledge from other countries to better prepare ourselves. Japan's Crusis shows the importance of TIMELY proper isolation and STRATEGICoperations logist ics in testing and in quarantine . South Korea (contrasting with Hong Kong, Singapore) demonstrates critica l importance of EARLYsocial distancing and high compliance community NPI intervent ion. China's latest lockdown of 1/2 billion people truly signifies that gravity and unchartered terrority of this virus. No country would take to such extreme measure. 7. CFR Since over 90% of influenza is never recorded/known, this COVID-19 seems to fall into similar spirit now, with so many cases of asymptomtic and transmission while incubating . While the true CFRremains unknown, the CFRof tested positive cases should offer a good comparison to the CFRof tested positive flu cases. That gives us a clearer estimate of health-resource burden. (b)(6) mobile: ----(b)(6) Sent with Prot onMa il Secure Email. ------- Original Message------On Saturday, February 22, 2020 10:19 PM, Carter Mecher Updates NIH-001467 --------- (b)(6)> wrote: South Korea (+123 with +2 deaths)- Total cases 556; Total deaths 4 https://www. cdc. go .kr/boa rd/board.es?m id=a3 0402 0O0O0O&bid=003 0 Singapore (+3)--Total cases 89; Total deaths 0 Hong Kong (unchanged)--Total cases 69; Total deaths 2 Japan- Total cases 135; Total deaths 1 Sent from Mail for Windows 10 From: Cart er Meche r Date: Saturday, February 22, 2020 6:28 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tra cey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR); DeBor d, Kristin (OS/ASPR/SPPR); Phill ips, Sally (OS/ASPR/SPPR); David Marcoz zi; Hepburn, Ma tthew J CIV USARMY (USA); Lisa Koo ni n; Wa rgo Mi chael ; Walte rs, Willi am (STATE.GOV); HARVEY, MELISSA; WOLFE. HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (O5/A SPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Lawle r, James V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade , ------- -- David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6J _ ,; KAUSHIK. SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 sta rt Roundup this morning . NIH-001468 Singapore and Hong Kong are holding steady- both have implemented NPis pretty early and have good surveillance . Things are really accelerating in South Korea. Case count increased to 433 with 2 deaths. https ://www .cdc. go .kr/board/board .es?mid=a30402000000&bid=0030 Report below of COVID hitting Samsung's mobile device factory, which has now been shut down. This is what will happen here. The greatest concern is what this would mean for critical infrastructure sectors (including components of our healthcare system), The strateg ies I outlined for outpatient clinics could be used by business (most especially CI sectors) to maintain business continuity. It is as simple as the old saying, "Don't put all your eggs in one basket." It is both contingency planning (continuity of operations /continuity of business) and application ofNPis/fLC (especially social distancing in the community supported by home isolation and home quarantine). We now have COVID in several countries across the ME (Iran, Israel, Egypt, Lebanon , UAE) . We added Iran the day before yesterday and 3 countries yesterday (Israel, Egypt and Lebanon). Iran already appears to have a well established outbreak that will be tough to slow down given the estimated size with 5 deaths already (that is where Wuhan was by Jan-20). Japan is also seeing acceleration with local transmission (119 cases). Italy is another area to watch. htt ps://p rotect2.fi reeye.com / ur l?k=c92f3372 -957b2a0e -c92f02 4d0cc47adc5fa29270 140238 19d8ec&u =htt ps://www .ilgazzett ino. it/no rdest/. .. D0yaq109ac4o 84 Numerous infected in the hospital of Schiavonia (Padua) "And unfortunately, what the experts feared since yesterday has occurred, when it was discovered that two patients had been hospitalized for about ten days at the Schiavonia hospital (Padua) without knowing that they had contracted the Coronavirus: since yesterday evening everyone those who attended the hospital were subjected to a swab to detect any infections, and the examination gave positive results in numerous cases. It means that there are other people, probably among those who attended the ward where tw o patients were hospitalized , who are now positive for the virus and consequently could in turn have spread the infect io n. Already yesterday evening the Governor of Veneta Luca Zaia ordered t he progressive evacuation of the Padua hospital which should take place within 5-6 days." NIH-001469 'The hospital is surrounded by a 'sanitary cordon' , with Carabinieri , workers of the Red Cross and Civil Protection . Cardiology chief Giampaolo Pasquetto aITived outside the hospital for a few minutes and reported the results of the swabs 'as far as I have been able to know from my colleagues so far,' he said. The modern structure is located between the towns of Este and Monselice and was recently inaugurated to serve the Euganean Hills area ." https://www.reuters.com /article/us-china-health-southkorea -samsung elec/samsung-electronics -confirms-coronav irus-case-at-phone-factorycomplex-in-south-korea-idUSKCN20G0CG SEOUL (Reuters) - Samsung Electronics said on Saturday that one coronavirus case had been confinned at its mobile device factory complex in the southeastern city of Gumi, causing a shutdown of its entire facility there until Monday morning. Samsung Electronics, the world's top smartp hone maker, said the floor where the infected employee worked would be shut down until the morning of Feb. 25. "The company has placed colleagues who came in contact with the infected employee in self-quarant ine and taken steps to have them tested for possible infection," Samsung said in a news release. Samsung's factory in Gurni accounts for a small portion of its total smartphone production , and it makes high-end phones, mostly for the domestic market. Samsung produces most of its smaiiphones in Vietnam and India. Gumi is close to the city of Daegu , home to a church at the center of South Korea's largest coronavirns outbreak. South Korea said on Saturday that the number of people infected with the coronavirus in the country had more than doubled to 433. Samsung said production at its chip and display factories in other parts of South Korea would not be affected. Sent from Mail for Windows 10 From: Carte r Mecher NIH-001470 Date: Friday, February 21, 2020 6:52 PM To: Richard Hatchett ; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duanei (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; W OLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Ro bert (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbro w . Gary (OS/ASPR/BARDA); Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (OS/ ASPR/1O); Hamel, Joseph (OS/ ASPR/ 1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/A SPR/1O); 'M art in, Gregor y J (b)(6) · Borio, Luciana; Hanfli ng. Dan; M cDona ld, Eric; Wade. David; TARANTI NO, DAVID A; W ILKINSON. THOMA S; David Grube r CbH6); KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start --------- ----------- Wuhan to add 19 addi tional hospital (when combined with the other 3 hosp itals, this would add 30,000 bed s). Just to put that in perspective. • There are 2.8 hospita l beds in the US per 1,000 population. • 30,000 beds is about the number of beds we would have for a popu lat ion of 11 M . When you add th e 30,000 beds plus the 13,348 other beds added (total of 43,300 bed s) • There are 4.5 hospita l beds in China per 1,000 populatio n • 43,300 beds is about the number of beds in China for a population of 9 .6 M • Wuhan will have nearly doub led its bed capacity How hard wou ld that be for us to double bed capacity in any major US city ? (Really isolation beds for mild illness) https: //www .straitstimes .com/ asia/east -asia/coronav irus -wuha n-toact ivate -one-more -ternporary-hosp ita l-with -3690beds?fbcli d=l wAR lotfl4xNxKiuB RuODJzoTDMJWHueF9gTc06u l I M9nM2u -3 VTpohO tFt7 s NIH-001471 WUHAN (XINHUA)- Wuhan, the epicentre of the coronavirus outbreak , plans to build another 19 mak eshift h osp itals to rece ive more infected pat ients, local aut horit ies said Frida y (Feb 21). Upon their completion, all the makeshift hospita ls in Wuhan are expected to offer 30,000 beds on Feb 25, said Mr Hu Yabo, deputy mayor of Wuhan at a press briefing on epidemic prevention and control. To date, Wuhan has converted 13 existing venues into temporary hosp itals, with a total of 13,348 beds , and about 9,313 beds have been put into use to treat patient s with mild symptoms, said Mr Hu. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Friday , February 21, 2020 1:59 PM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6) Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.; (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/10); Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_<6> _ ,; KAUSHIK. SANGEETA; Natha niel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- Week ly CDC update looks like flu m ight be on the downs lope (good new s). Watch ing the curves of % posi tive flu tests and ILi (should track one another as flu is receding). Tro uble is the data reported today is for the week ending Feb 15 (so a week old). NIH-001472 Our inpatient nursing sick leave is tracking ILI (current thru 2/20)- nothing unusual Sent from Mail for Windows l 0 From: Carter Mecher Sen t: Friday, February 21, 2020 10:54 AM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey M cNam ara; Caneva, Duane , CbH6)1; Dodgen , Dan iel (0 S/ASPR/SPPR); DeBor d, Krist in (OS/ASPR/SPPR); Phillips, Sally (0S/AS PR/SPPR): David M arcozzi; Hepburn. M att hew J CIV USARMY (USA): Lisa Koonin; W argo M icha el: Walt ers , William (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastm an, Alexander ; EVANS, MARIEFRED: Callahan, M ichael V.,M .D.. (b)(6) Johnson, Rober t (05/AS PR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd. Johnt(OS/ASPR/SPPR) ; Hassell , Dav id (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10 ); 'Mart in, Gregory J (b)(6) '; Borio, Luciana ; Hanfli ng, Dan; M cDona ld. Eric; Wad e, -------- David ; TARANTINO. DAVID A; W ILKINSON. THOMAS; David Gru ber (b)(6) KAUSHIK, SANGEETA; Natha niel Hupe rt ------------ Subject: RE: Red Dawn Breaking , COVID-19 Collaborative , Feb 16 start Singapore and Hong Kong are holding the line. Both implemented NPls early. No change in numbers from Hong Kong and Singapore saw its case count increase by only 1 for the past two days. Japan reported to have 107 case s. First reported case in young children (se below) Hokka ido boy 1st Ja pa n case of coronaviru s infection under 10 February 21. 2020 (Mainichi Japan ) NIH-001473 SAPPORO-- Two elementary school brothers and a woman in her 40s in Hokkaido have been infected with the new coronavirus, wi t h t he younger sibling becoming the first infection under 10 in Japan, Hokkaido Gov. Naomichi Suzuki announced on Feb. 21. Some graphics of the drop off in trave l in China (pretty dramatic) Jan-23 Feb-13 Sent from Mail for Windows 10 From: Carter Meche r Se nt : Friday, February 21, 2020 10:28 AM To: Richard Hat chett ; Dr . Eva K Lee Cc: Tracey McNama ra; Can eva, Duane i (b)(6); Dodge n, Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepbu rn . Ma t thew J CIV USARMY (USA); Lisa Koo nin: Wa rgo Mich ael; Wa lters , W illiam (STATE.GOV): HARVEY, MELISSA; WO LFE, HERBERT; East man , Alexa nder ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Rober t (OS/ASPR/BARDA); Yeskey. Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd. Johnt (OS/ASPR/SPPR); Hassell. David (Chris) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean. Char ity A@CDPH; Law ler, James V; Kadlec. Robert (OS/ASPR/1O); 'M art in, Grego ry J (b)(6); Borio. Luciana ; Hanfli ng. Dan; McDon ald, Eric; Wade. David ; TARANTINO, DAVID A; W ILKINSON. THOMAS : David Grube r ( CbH6XKAUSHIK, SANGEETA: Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- NIH-001474 https://www. cdc.go.kr/board/b oard.es?mid=a3040200000 0&bid =0030 Here is the best link to track cases in South Korea. South Korea is now up to 204 cases and 1 death (South Korea is where Wuhan was 1 month ago). Sent from Ma il for Windows l 0 From: Carter Mecher Date: Friday, February 21, 2020 10 :02 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane (b)(6); Dodgen, Daniel (OS/ASPR/SPPR); 0eBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, Matthew J CIV USARMY {USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASP R/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J (b)(6) · Borio, Luciana; Hanfl ing, Dan; McDonald, Eric; Wad e, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber CbH6J;KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start -------- ----------- On a totally diffe rent note. Others have been plying with and modify ing the notiona l conops for a healthcare system. I set up some simple rules : 1. Protect uninfected patients and staff from infectious patients and staff (using all the tools that we have includin g home isolation and home quarantine , cohorting/physical separation, PPE, telehealth, etc.) 2. Provide acute care for COVID pat ie nts (cont inuum of ER-inpatient care-intensive care) 3. Support mildly ill COVID patients in home isolation --telehealth 4. Support patients in voluntary home quarantine- -te lehea lth NIH-001475 5. Continue to address the usual mix of healthcare needs for patients (from outpatient care to acute care to mental health care to long term care) a. Outpatient clinics and providers focus on wellness to minimize ERvisits/hospitalization to unburden the acute care system-leverage telehealth b. Continue to provide acute care and inpatient mental health care (continuum of ER-inpatient care-intensive care) for nonCOVID conditions c. Protect high-risk patients in residential/long term care (n ursing homes, hospice, long term psychiatry, etc.) The notional conops divides the healthcare system into hot and safe areas. The hot area is only acute care: ER-acute inpatient care-ICU care. The safe areas include a separate acute care area (ER-acute inpatient care-ICU care), all the outpatient clinics/care, other inpatient care areas such as mental health, as well as long term/residential care (nursing home, hospice , long term psychiatry, etc.). Triage will not be easy (between hot and safe). Best I could come up with would be: ( 1) anyone already on home isolation or home quarantine (may need a medical record flag); (2) anyone with ILI (could narrow that down with a negative rapid flu test); (3) anyone with a sick household member with suspected COVID. Could be very difficult for an unconscious /confused, or trauma patient etc., but would probably err on the side of hot and think of additional layered strategies to minimize patient risk within that area (private rooms, patient PPE?). Triage would need to err on the side of keeping the safe area safe. The mitigation measures are our best tools to reduce community transmission and reduce the probability of an infectious patient getting into a safe area. If we have a breach in a safe inpatient area, it pretty much converts that inpatient area into a hot area. That also means that we have the staff in that area exposed (because of limited availability of PPE, the staff in the safe area would not be PPE-PPE would have been directed to the staff in the hot area). Those staff would likely need to be placed on quarant ine. The effect is we now have a much larger hot area with even fewer staff. That would really be a mess. NIH-001476 You have the same problem in the outpatient areas. Have a sick patient slip through and come in contact with a number of the clinic staff (not in PPE), and we now need to quarantine all those staff. In contrast to a breach for the inpatient area, the outpatient area can still operate as a safe area (just minus those staff who would now be on quarantine). But do that a few times and pretty soon you have nobody left to fight. One way I thought about dealing with this scenario is to take the outpatient staff and split them in two. One group works the clinic (physically present) for the usual clinic hours for a 14 day stretch (1 incubation period) . Another group works from home (and practices social distancing, etc., really acting as if they are on home quarant ine) and leverages telehealth technology to care for patients and help with monitoring those patien ts in home isolation and home quarantine. After 14 days the groups switch. [All along we monitor employees daily (whether at work or at home) for symptoms or sick household membe rs] In the event of a breach , the groups immediately switch and the group that was working is placed on actual home quarantine (but still continues to work from home leveraging telehea lth) . That way if a breach does happen, we have a fallback response (that we are constantly practicing) that allows us to sustain outpatient care. For the inpatient areas, I thought about the lone survivor model (holding back 1 Secretary and staff in the event that the government is decapitated). So think of a small group (would need to think thru what the composition of that team would look like for each area (acute care, inpatient mental health, long term care) that would at least provide the nucleus of the expertise necessary to reconstitute the service in the event of a major breach). This smaller group would vary in team members every 2 weeks and would rotate to work from home for 14 days stretches and pract ice social distancing (acting as if they were on home quarantine). They could also assist via telehealth (inpatient consultation , etc., while out of the hospital). Is anyone thinking along these lines (really continu ity of operations for the healthcare system)? Sent from Mail for Windows 10 NIH-001477 From: Carter Mecher Date: Friday, February 21, 2020 8:35 AM To: Richard Hatch ett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); OeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Michael ; Walters, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT ; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; Cb)( Johnson, Ro bert (0S/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell. David (Chris) (0S/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) ; 'Mart in, Gregor y J (b)(6) '; Borio, Luciana; Hanfling, Dan; McDonald, Eric; Wade , David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ Cb _ >_C6) _ ,; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - https: // www.cbc.ca/news / canad a/ ottawa /d iamond -princ ess-coronavirus- tr enton-comw all-l .54 70386 Canada flies home passengers from cruise line . Data in article : 47 of 256 Canadians contract https://protect2.fi reeye.com/url?k=96ebd7bc -cabfcec0 -96ebe6830cc47adc5fa2 16a39afbe c00c653&u=https ://www.t imesofisrael.com/israe l ... need iagnosed/ Israel confirms first coronavirus case as cruise ship returnee diagnosed One of 11 Israel is who arrived in the morning after quarantine aboard Diamond Princess ship tests positive, after entering 14-day isolation at Sheba Medical Center Trying to track cruises ship passenger /crew by country (data is sketchy) Country Passengers/Crew us 434 Total ICU % Confirmed Admissions Deaths Infected Cases l? 13% 58 NIH-001478 Hong Kong Canada 330 Australia 241 78 UK Ita ly South Korea Israel 256 47 48 20% 6 8% 1 9% 18% 35 14 11 2 Japan Subtotal 1,399 160 Tota l 3,711 634 Sent from Mail for Windows 10 From: Carter Mecher Date: Friday, February 21, 2020 5:46 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara; Caneva. Duane; (b)(6); Dodgen. Daniel (0S/ASPR/SPPR) ; DeBord. Kristin (OS/ASPR/SPP R); Phillips. Sally (0S/ASPR/SPPR ); David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koonin; Wargo Michael ; Walters. William (STATE.GOV); HARVEY. MELISSA ; WOLFE. HERBERT; Eastman. Alexander; EVANS.MARIEFRED; Callahan, Michael V.,M.D.1 (b)(6); Johnson, Robert (05/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR) ; Hassell, David (Chris) (0S/ASPR/10) ; Hamel, Joseph (0S/ASPR/10) ; Dean, Charity A@CDPH; Lawler, JamesV; Kadlec, Robert (0S/ASPR/10) ; 'Mart in, Gregory J (b)(6) _... '· Borio, Luciana; Hanfl ing. Dan; McDonald, Eric; Wade, David; TARANTINO. DAVID A; WILKINSON,THOMAS; David Gruber (b)(6); KAUSHIK.SANGEETA; Nathan iel Hupert Subject: RE:Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start _______ ---------- China ha s again mod ified its reportin g (first it added clin ical cases to lab confirmed cases on Feb-12). Now it is subtracting out those clinical cases and limiting numbers to lab confirmed). Have continued to follow the hospitalization data from Hubei (see below). NIH-001479 17% Here is the data being reported by Hubei and Wuhan. Data is pretty sketchy prior to Jan-21. Hubei and Wuhan Cases Hospi talization Rates Hubei Wuhan Tota l Wuh Cum Cum Mild Sever Critic Cum Cum Cum Hubei Current an Hospitali Hospitali Date Disea ely ally Discha Death Inpatie Cum Inpatie Case zation zation se Ill Ill rges nts cases s nts s Rate per Rate per 100,000 100,000 1/ 14/ 6 6 6 41 41 0.01 0.5 20 1/15/ 5 5 2 41 41 0.01 0.5 7 20 1/ 16/ 45 2 45 0.01 0.5 5 5 7 20 1/17/ 8 2 10 62 62 0.02 0.7 8 20 1/ 18/ 121 121 0.2 1.4 136 100 33 3 3 139 20 1/ 19/ 4 170 126 35 174 198 198 0.3 2.4 9 20 1/20/ 239 176 51 12 7 246 270 258 0.4 3.1 20 1/21/ 15 375 320 0.0 3.8 20 1/22/ 304 71 24 17 416 444 390 0.7 4.7 399 20 1/23/ 494 24 31 549 549 495 5.9 365 106 23 0.9 20 1/24/ 472 129 57 729 729 572 1.2 6.8 658 32 39 20 1/25/ 915 221 85 52 1,052 J,052 618 1.8 7.4 20 1/26/ 44 1,645 1,013 563 69 2.4 8.3 76 1,423 1,423 698 20 1,59 1/27/ 4.6 19.0 2,567 1,877 563 127 47 100 2,714 2,714 20 0 1/28/ 1,90 3,349 2,450 671 228 80 125 3,554 3,554 6.1 22.8 20 5 1/29/ 2,26 4,334 3,346 711 277 162 4,586 4,586 7.8 27.0 90 20 1 1/30/ 5,486 4,392 804 290 116 204 5,806 5,806 2,63 31.5 9.9 Hubei 2019-nCoV Confirmed Hospital Data NIH-001480 & ¾ Hube i Cases Hospita lized 100% 100% 100% 100% 100% 100% 100% 100% - ,- 20 l /31I 20 2/1/2 0 2/2/2 0 2/3/2 0 2/4/2 0 2/5/2 0 2/6/2 0 2/7/2 0 2/8/2 0 2/9/2 0 2/ 10/ 20 2/11/ 20 2/12/ 20 2/13/ 20 2/ 14/ 20 2/15/ 20 2/ 16/ 20 2/17/ 20 2/ 18/ 20 2/19/ 20 2/20/ 20 6,738 5,444 956 8,565 7,003 9,618 7,917 10,990 8,857 12,627 14,314 15,804 19,835 20,993 22,160 25,087 26,121 33,693 36,719 38,107 39,447 40 814 41 957 43,471 43 745 42,056 10,10 7 11,23 0 11,80 2 14,64 0 15,74 6 16,65 5 18,74 3 18,88 0 26,60 9 27,08 1,118 1,223 1,557 1,809 2,328 3,161 338 166 249 7,153 7, 153 444 215 294 9,074 9,074 478 295 350 576 396 414 711 520 479 756 633 549 841 817 618 1,113 699 1,439 780 1,795 871 2,222 974 4,188 1,007 4,093 1,154 4,269 1,236 5,046 1,298 5,724 1,517 5,647 1,437 7,953 1,685 ] 27,95 5 29,05 1 31,01 7 30,98 7 32,22 5 32,56 7 3 1,05 8,276 1,876 8 439 1,957 8,024 1,773 9,117 1,853 9,289 1,957 2,639 1,068 3,441 1,310 4, 131 1,426 4,774 1,457 5,623 1,596 6,639 1,696 7,862 1 789 9,128 1,921 9,128 2,050 10.337 8,979 2,018 11,788 9 NIH-001481 2,029 2, 144 10,263 11,177 11,800 13,522 13,626 16,678 15,496 19,665 17,239 22,112 21,647 24,953 23,212 27,100 24,826 29,631 28,283 31,728 29,828 31,728 38,444 48,206 42,276 5 1,986 44,338 54,406 46 666 56,249 49, 149 58,182 51,608 59,989 54,520 6 1,682 56,111 62,013 55,988 62,422 9 3,21 5 4,10 9 5,14 2 6,38 4 8,35 l 10,1 17 11,6 18 13,6 03 14,9 82 16,9 02 18,4 54 18,4 54 32,9 94 35,9 91 37,9 14 39,4 62 41,1 52 42,7 52 444 12 45 ,0 27 45,3 46 12.2 38.4 100% 15.5 49.l 100% 17.5 56.4 92% 20.2 66.6 87% 23.3 81.6 82% 26.5 95.3 79% 29.5 108.3 78% 37.0 141.1 87% 39 .7 153.4 86% 42.4 169.3 84% 48.3 196.7 89% 51.0 207 .4 94% 65.7 314 .6 80% 72.3 349 .9 81% 75.8 369.4 81% 79.8 39 1.4 83% 84.0 415 .6 84% 88.2 439 .7 86% 93 .2 469 .3 88% 95.9 487 .0 90% 95.7 486 .2 90% Sent from Mai l for Windows l 0 From: Carte r M eche r Date: Friday, February 21, 2020 5:09 AM To: Richa rd Hat chett ; Dr . Eva K Lee Cc: Tracey M cNama ra; Caneva. Duane; Dodgen . Daniel (OS/ASPR/SPPR); DeBord , Kri stin (OS/ASPR/SPPR); Phill ips. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walte rs, William (STATE.GOV); HARVEY, (b)(6); MELISSA; WO LFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris ) (OS/ASPR/1O); Hame l, Joseph (OS/ASPR/1O); Dean . Char ity A@CDPH; Lawler . James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in. Gregory J (b)(6 ) Borio. Luciana ; Hanfl ing. Dan; McDona ld. Eric; Wade , David; TARANTINO, DAVID A ; W ILKINSON, THOMAS ; David Gruber _________ Cb _ )_(6) _ ,; KAUSHIK, SANGEETA ; Nathan iel Hupe rt -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start More on South Korea (soundsjust like what happened at Jefferson Barracks, just outside St. Louis, in 1918, armed with the exact same tools they had more than 100 years ago to control an outbreak ). I assume they must also be taking measures within the base to limit spread (keeping infect ious individuals apart from those not yet infected with isolation and quarantineand social distancing). https://en.yna.co.kr/view/AEN2020022l 003000325?section=national/d efense SEOUL, Feb. 21 (Yonhap) -- The military is making all-out efforts to prevent the new coronavirus from spreading further into the barracks, offic ials said Friday, after the country's first infections in the armed forces we re confirmed . Earlier in the day, a Navy sailor on the southern island of Jeju was confirmed to have contracted COVID-19 in the first such case among service_personnelhere. NIH-001482 Follow ing the confirmat ion, the Navy has checked the temperature of all personne l at the base where the infec ted sai lor served and quara ntined all those who had contacts with the pe rson, it said. "We have carried out disinfec tion work at the base and are devoting all our efforts to preven ting the spread of the new virus," the Na:vy said in a release. An officer each from the Army and the Air Force were also confirmed to have the virus the same day. The military is now wo rking to ident ify personnel who have visited the southeastern city of Daeg u and the suffound ing Nort h Gyeong sang Province since Feb . 10, as these areas have rece ntly seen a surge in the number of infected people. More than 5,000 service persom1el are estimated to have visited the region during their vacat ion accord ing to the military's preliminary inve stigatio n. On Thursday night the defense ministry said all personnel will be barred from vacationing, staying outside their bases and meeting v isitors starting Saturday. The decision was made at a meeting of top defense officials presided over by Defense Minister Jeong Kyeong-doo, during which he called for "extraordinary measures" to contain the s read of the virus . Amid growing fears over the disease , the govemment called off a planned ceremony to mark the 60th ann iversary of a pro -democracy movement in Daegu, which was designa ted a "special care zone" over the virus earlier in the day. Sent from Ma il for Windows l 0 From: Carte r M eche r Date: Thursday, February 20, 2020 9:21 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane; (b)(6); Dodge n. Dani el (OS/ASPR/SPPR); DeBord. Kristin (OS/AS PR/ SPPR); Phillips. Sally (OS/ASPR/SPPRl : David M arcozzi: Heob urn , M att hew J CIV USARMY (USA); Lisa Koo nin ; W argo M ichael; Walt ers, W illiam (STATE.GOV); HARVEY, NIH-001483 MELISSA; WOLFE. HERBERT; Eastman , Alexa nder ; EVANS. MAR IEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (OS/ASPR/10) ; Dean , Charity A@CDPH; Lawl er, Jame s V; Kadlec, Robert (OS/ASPR/10 ); 'Ma rt i n, Gregory J (b)(6) · Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric ; Wad e, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gru ber (b)(6)· KAUSHIK, SANGEETA; Nat hanie l Hup ert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- ----------- S. Korea reports 52 new virus cases, total now at 156 Welfare /Medicine 10:37 February 21, 2020 SEOUL, Feb. 21 (Yonhap)-- South Korea reported 52 new cases of tbe new coronavirus Friday, bringing the total numbe r of infections in the nation to 156, with the potentially fatal illness spreading fast across the country. The number of COVID-19 infections here has almost tripled in just three days, with most new infections traced to church services in the southeastern city of Daegu. Of the 52 new cases, 41 are in Dae gu, 300 kilometers southeast of Seoul, and the neighboring North Gyeongsang Province. Another three were reported in Seoul, the Korea Center for Disease Control and Prevention (KCDC) said in a statement. Tour buses are parked at a logistics terminal in Daegu , 300 ki lometers southeast of Seoul, on Feb. 20, 2020. Thirty-eight new coronavi rus cases were reported in the city on Feb. 21, 2010. (Yonhap) The spike of infections in Daegu and several cases in Seoul , where routes of infection s are not immediately traceable , have prompted health offic ials to declare that COVID-19 has begun spl!_ading locally. The KCDC said two new cases were reported in South Gyeongsang Prov ince . In a sign that the virus may broadly spread nationwide , six prov inces, includ ing Gyeong gi, Jeju , Chungcheong and North Jolla, each repo rted one case. NIH-001484 Of the 52 new cases, 39 are linked to the Shincheonji Church of Jesus in Daegu , where the 31st patient, the country 's probab le "super spreader ," attended worship serv ices, the KCDC said. A 61-year-old South Korean woman, who tested positive for the virus earlier this week, attended worship serv ices at the church on Feb . 9 and this past Sunday . KCDC Director Jung Eun-kyeong told reporters Thursday that the agency is uncertain whether the woman , known as the 31st patient , was a "super spreader" of the virus but asked 1,001 membe rs of the church to self -isolate to stem the spread of the virus . The government decided to designate Daegu and neighboring Cheongdo as "special management zones," following the spike in the number of infected people and the nation's first death from the virus. Sent from Mai l for Windows 10 From: Carte r Mecher Date: Thursday, February 20, 2020 5:38 PM To: Richa rd Hat chet t; Dr. Eva K l ee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6) Dodgen , Danie l (OS/ASPR/SPPR); DeBo rd. Kri stin (OS/ ASPR/SPPR); Phill i ps. Sally (OS/ASPR/SPPR); David Marcozzi : Hepburn. Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Mi chael ; Wal t ers, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MARIEFRED; Callahan , M ichael v .,M .D.; (b)(6) Johnson , Robert (0S/AS PR/ BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt( OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASP R/ I0) ; Hamel , Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Lawler , James V; Kadlec. Robert (OS/ASPR/10); 'M art in. Grego ry J (b)(6J 1; Borio. Lucian a; Hanfli ng. Dan; McDona ld, Eric; Wade. David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grube r __________ Cb _) _(6J;KAUSHIK, SANGEETA; Nathan iel Hupe rt -------- Subjec t: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start From Feb-15 to Feb-20 the number of confirmed cases increased from 355 to 634 (increase of 279). The number of asymptomatics increased from 73 to 322 (increase of249) . So from Feb-15 to Feb-20 , 249 of the NIH-001485 279 confirmed cases (89%) were asymptomatic. Seems a little odd. Also, read reports that all passengers and crew have beem tested (but report s only note that 3,066 of the 3,711 have been tested) . Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb 15-Feb Eve nt Cruise ship depa1is from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confirmed to have COVID-19 When results known, certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms, those who got off in Hong Kong , and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confirmed + 31 more passengers and crew confinned + 30 more passenger and crew confinned + 9 more passenger and crew confirmed + 66 more passenger and crew confinned + 39 more passenger and crew confinned + 28 more passenger and crew confirmed+ 15 more passenger and crew confomed + 67 more passenger and crew confinned + 70 more passenger and crew confirmed+ NIH-001486 Cumulative Number of Confirmed Cases Cumulativ eNumber of Deaths Notes 10 41 61 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 355 1,219 tested; 73 asymptomatic 16-Feb 329 American evacuated from cmise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Amer icans remained hosp italized in Japa n 17-Feb 85 more passenger and crew confirmed+ 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 369 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 2 3,066 20-Feb 13 more passenger and crew confirmed+ 634 Sent from Mail for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 4:49 PM To: Richa rd Hat chett ; Dr. Eva K Lee Cc: Tracey Mc Nama ra; Caneva, Duane; (b)(6); Dodgen, Dan iel (OS/ASPR/S PPR); DeBo rd, Kri stin (OS/ASPR/SPPR); Phill i ps, Sally (OS/ASPR/S PPR); David M arcozzi ; Hepburn , Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Mi chael; Walte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexande r; EVANS, MA RIEFRED; Callahan, M ichael V.,M .D., (b)(6) _; Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd, Johnt(OS/ASP R/S PPR); Hassell, David (Chris) (OS/ASPR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Ma rt in, Grego ry J (b)(6) · Borio, Luciana ; Hanfli ng, Dan; McDona ld, Eric; Wade, -------- David; TARANTI NO, DAVID A : W ILKINSON. THOM AS: David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupe rt Subjec t : RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- NIH-001487 2 tested; 28 seriously ill; 322 asymptomatic This is new • Now 634 cases confirmed on the cruise ship (3,063 tested) (so not all the ship and crew have been tested 3.711) • Slightly more than half are asymptomatic (previously we heard that 73 of 355 are asymptomatic) • 28 in serious condition (4.4%) Japan's Health Min ister Katsunobu Kato told Parliament the t\vo people from the Diamond Princess cruise ship who died had "received the best medica l treatment" but couldn't be saved after catching the novel corona virus on board. As of Thursday, 634 passengers and crew members were diagnosed with the virus out of 3,063 tested. Slightly more than half have no symptoms at all, officials said, and many of the remainder have only mild fever or a cough. Among patients who tested positive for the virus, 28 were reported in serious condition Thursday. Doctors have said the vims can be particularly harmfu l in elderly patients , and one of the two fatal cases from the Diamond Princess, a Japanese man in his 80s, had pre-exist ing bronchial asthma and had been treated for angina. The other, a Japanese woman in her 80s without underlying illnesses, came down with a fever on Feb. 5, the same day passengers were told they would be quarantined in their cabins for two weeks, according to health ministry officials. The next day, she started suffer ing from dianhea and saw a doctor on board. She wasn't taken to a hospital until Feb. 12 when she started suffering shortness of breath. Her virus test came back posi tive the following day, and despite treatment with antivira l drugs norma lly used to treat HIV infection, she died Thursday. Asked about the woman's case, health ministry official Hiroshi Umeda said, "I believe it was hand led promptly." He said the ship was a difficult environment for medica l staff but they worked day and night and tried to prioritize the most serious cases. Sent from Mai l for Windows l 0 From: Carte r Mec her Sen t : Thursday, February 20, 2020 11:00 AM To: Richard Hatc hett ; Dr. Eva K Lee Cc: Tr acey Mc Nama ra; Caneva, Duane; (b)((;); Dodgen, Daniel (OS/ASPR/S PPR); DeBord, Kristin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/S PPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); NIH-001488 Lisa Koo nin; Warg o Mich ael; Walters. W illiam (STATE.GOV); HARVEY. MELISSA; WOLFE. HERBERT; Eastma n. Alexander; EVANS. MARIEFRED: Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/IO); Hamel, Joseph (OS/ASPR/ IO); Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/IO) ; 'M art in, Gregory J ,.._ _____ Cb _>_<6J _,,_, ' · Borio, Luciana; Hanfl ing, Dan; M cDonald, Eric; Wade, David; TARANTINO, DAVID A; W ILKINSON, THOM AS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nat haniel Hupe rt Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ----------- Keep an eye on South Korea too. Seeing rapid growth in cases in South Korea (see story below) South Korea now reporting 104 cases and 1 death today. South Korea now implementing NPi s. This story is eerily remini scent of the actions taken at Jefferson Barracks near St. Louis in 1918. Also attached are update for Singapore (85 cases; 46 in hospital/4 in ICU; 4 kids, only l in hospita l) and Hong Kong (69 cases, still no kids report ed). Both have implemented NPis (small increases in cases today). Japan has reported 10 new cases today-total now is 94. South Korea reports first virus death as Daegu struggles to contain outbreak htt ps://p rot ect 2.fi reeye.com/ur l7k=3b90 7Sda-67c46ca6 -3b9044e50cc47adc5fa2 08635f0e3 1f1241 a&u=https://www .stri pes.com/news/p acific ... break1.619407 SEOUL,South Korea - South Korea reported its first coronavirus-linked death Thursday, while the U.S. military tightened restrictions on travel to the southeastern city of Daegu due to an outbreak in infections in the area. Daegu also urged resident s to stay home as the city of 2.5 million people and surrounding areas struggled to contain an outbreak of the pneumonia-like disease . The Army garrison in Daegu also restricted access and announced that schoo ls and nonessential business would be closed for a second day on Friday. NIH-001489 In an exception to policy, U.S. service members were authorized to wear face masks in uniform "regardless of air quality condit ions," according to the ga1Tison' s F acebook page. Fast-moving developments this week were a blow to South Korea's hope that the crisis was easing. Instead, dozens of new cases were confirmed in recent days, with the total number of infections soaring to 104 on Thursday, according to the Korea Centers for Disease Control and Prevention U.S. Forces Korea said, "there remains zero confirmed cases ofUSFK personnel with COVID-19." The virus first appeared in December in Wuhan, China, and spread to nearly 30 countries. More than 2,000 people have died - most in mainland China. A South Korean man in his 60s died Wednesday at a hospital in the sout heastern city of Cheongdo and posthumously tested positive for the virus , the KCDC said Thursday. It was South Korea's first death from the virus. USFK raised the risk level for the militar y communit y to moderate on Wednesday and banned all nonessential travel to Daegu due to an outbreak linked to a church near the Anny garrison in the city. On Thursday, USFK added that all travel by American troops to, from and around Daegu requires authorization from their leadership. The precaution was "highly encouraged" for all family members, civilians and contractors as wel l. "All off-insta llation travel for all USFK populations should be minimized to reduce potential contam ination," USFK announced on its website. U.S. Army Garrison Daegu, about 200 miles southeast of Seoul, also said visitors not performing mission essential or official business would be denied access as it implemented health checks at the gates. Nonessential personnel were not required to go to work on Friday and most activities would be suspended , including the schools , it said. The garrison also recommended that members of the military commun ity avoid public places and transportat ion in the c ity, includin g NIH-001490 stores, restaurants and other heavily congested areas until the situat ion is brough t under control. Self-quarant ine measures were ordered for any Amer ican troops who had visited the affected New World Church, but garrison commander Col. Edward Ballanco said earlier Thursday that no Americans were known to have done so. He also urged Americans to avoid a local hospital where the woman believed to have been a carrier was treated. The garrison also lifted limits on wearing face masks for American troops in uniform, who normally are only allowed to wear them on days with extreme pollut ion. Sent from Mai l for Windows 10 From: Carte r Mec her Date: Thursday, February 20, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNa mara ; Caneva, Duane ; (b)(6); Dod gen, Daniel (OS/ASPR/S PPR); DeBo rd, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David M arcozzi; Hepburn, M att hew J CIV USARMY (USA); Lisa Kooni n; Wa rgo M ichael; Wa lte rs, Will iam (STATE.GOV); HARVEY, MELISSA; W OLFE. HERBERT; Eastm an. Alexande r; EVANS, MARIEFRED: Call ahan, M ichael V.,M .D.J (b)(6); Johnson , Ro bert (OS/ASPR/BARDA); Yeskey, Kev in; Disbro w, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/AS PR/SPPR); Hassell, David (Chris) (0S/AS PR/I0) ; Hame l, Joseph (OS/ASPR/ 10) ; Dean, Charit y A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)( ' ; Bo rio, Luciana; Hanfli ng, Dan; M cDo nald, Eric; W ade, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber _________ _> Cb _ C_6) KAUSHIK. SANGEETA; Natha niel Hupert -------- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Last thing. Keep a very close eye on Japan. The outbreak is starting to take off there with number s of cases scattered across the country with no link to known cases. We are also seeing nosocomial transmission (a number of healthcare workers infected). There is also a large number of cases hospitalized in Japan related to the cruise ship, and now the release of large mLmbers of passengers from the cru ise ship into the community. Yesterday they reported a total of 84 cases-caught up to NIH-001491 Singapore. But unlike Singa pore , Japan has been slow to implement NPis. The other concern is that Japan's popu lation is disproportionately aged (it has the highest% age 65 of any country). In Ja pan, 27% of the population is :::_ 65; in the US, 15.6% of the population is~ 65. And Japan can also claim the largest city in the world (metro Toky o with 38 M people - pretty much the populat ion of California crammed into an area smaller than the size of Conn ecticut). Japan also has the 1oth largest city in the world (Osaka wi th 19 M people). Sent from Ma il for Windows 10 From: Carter Mech er Date: Thursday, February 20, 2020 7: 15 AM To: Richard Hat chett ; Dr. Eva K l ee Cc: Tracey McNam ara; Caneva, Duan e; (b)(6) Dodg en, Dani el (OS/ASPR/SPPR); 0 eBord, Kri stin (OS/AS PR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi; Hepb urn , M atth ew J CIV USARMY (USA); Lisa Koo nin; Wargo M icha el; Wal te rs, Wi lliam (STATE.GOV); HARVEY, M ELISSA; W OLFE. HERBERT; East man , Alexan der; EVANS. MARIEFRED; Callah an. M ichael V.•M .D.; (b)(6) Jo hnson. Rober t (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt (OS/ASPR/SPPR); Hassell, Dav id (Chris) (OS/ASPR/IO); Ham el, Joseph (OS/ASPR/1O); Dean, Chari ty A@CDPH; Law ler , Jame s V; Kadlec, Robert (OS/ASPR/1O); 'M art in, Gregory J (b)(6) Borio, Luci ana; Hanfli ng, Dan; M cDon ald , Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grub er _________ Cb _H_6) KAUSHI K. SANGEETA; Nath an iel Hu pert -------- Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start What has me worried is what happened on the crui se ship is a preview of what will happen when this virus makes its way to the US healthca re sys tem (no t to mention institutionali zed h igh-r isk population s in the US, like nur sing homes) . I'm not sure that folks und erstand what is ju st over the hor izon. Remem ber the story about Mann Gulch ? We are at the equiva lent of abou t 5:44. I anticipate that when we reach 5:45, th ere is go in g to be chaos and panic to get anything in place. I doubt that what we would NIH-001492 then hurriedly put in place will be any better than what they did on that cruise ship. As a conseq uence, would expect much the same results. I listened to the discussion yesterday. After listening to James and Michael describe the conditions on and around the cruise ship, I wondered whether anyone in healthcare leadership ( outside the expert ise at our biocontainment facilities) is thinking about infection control practices for any staff entering areas of a hospital caring for COVID patients (like changing clothes before entering and perhaps wearing scrubs, not bringing personal items into the area like iphones, ipads, stethoscopes, white coats, purses, briefcases , etc .)? And instituting policies that require all patients to phone for clearance to enter prior to presenting at safe acute and non-acute areas including community based clinics? Are we confiden t of the infection control practices of acute care staff (that they know the basics of how to don and doff PPE and behavior while in PPE?) Would HCWs in outpatient clinics or long tem1 care facilities be any better prepared than the crew on board the cruise ship or the responders in Japan? I'm no expert in infection control and would defer to the expertise in this group. I was jus t a little smprised how little this seemed to be a concern for the healthcare leaders gathered yesterday. I think we are getting close to the point where we need to drop those things that are not critical and focus on the most imp01tant things. We are going to have a devil of time with lab confirmation - it is just too slow (they had a 2 day turnaround on the cruise ship) and we just don't have the capacity for the volume of tests we would anticipate. Charity has stressed this point again and again. That means we are going to have to fly blind early on. Perhaps the best we are going to be able to do in the near term if things begin to acce lerate is screen all suspect cases (pretty much anyone with ILi symptoms) with a quick flu test and assume anyone who tests negative is suspected COVID until proven otherwise; and treat everyone who tests positive with Tamiflu. It will prove problematic early on, but as the epidemic barrels along, COVID will displace everything (at that point we will just assume that anyone with a fever or ILi has COVID). The problem is in the beginning . It is going to be so hard to sort things out. Matt, James and others are pushing for more rapid screening- but we ju st aren't there yet. The consequence is that we will be placing patients with resp illness (that is not flu and presumed to be COVID) in areas with actual NIH-001493 COVID patien ts. I hate to do that, but not sure how it could be avoided early on. But we wou ld only do that for those who are ill enough to be hospitalized. The large number of asymptomatic and mildly ill patients would be under home isolation (so no worries about mixing confinned and suspected patients). The downside is that we would have larger number of people is isolation and home quarantine than is really necessary (and the consequence of increased workplace absenteeism). And it is because home isolation and home quarantine are so important, healthcare systems (and not ju st public health) have to grab a hold of operationalizing those NPi s with both hands. A while back, I created some prescriptions (tongue in cheek), just to underscore that physicians do have a role in isolation and quarantine (it is not limited to public health). We might not have pharmaceutica ls available to treat COVID, but why can' t we write pre scriptions for non-pharmaceutica ls? I don't think healthcare leaders appreciate this point. Every COVID pat ient we admit or see in the ER will require us to follow up with household members to make sure they know to home quarant ine (need to do the same anywhere in our system we find a patient who is infected). You could not imagine the pushback I have received when I proposed that we must have an active role-people seem to think that state and local public health is alone respons ible for this. I would think public health will be overwhelmed and taking charge of this is our best strategy to keep our safe areas safe. I would be interested to hear how other healthcare systems and public health leaders are thinking about this. Sent from Mail for Windows 10 From: Carter Mecher Date: Thursday, February 20, 2020 6:39 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva. Duane (bH ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Krist in (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepb urn, M atthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Wa lters, W ill iam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; East man, A lexander ; EVANS, MARIEFRED; NIH-001494 Callahan. M ichael V.,M .D.; (b)(6); Johnson, Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hame l, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber (b)(6); KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------- - ----------- Keeping track of the outbreak aboard the cruise ship. The latest update is the announcement of 2 deaths (both patients in their 80s). An 87year-old man and an 84-year-old woman, died on the 20th. Both were Japane se (the 87-year-old man was hospitalized on Feb-11 and the 84year-old women on Feb-12). So time to death from recognition of infection was 8-9 days. On Feb-12 , the total number of confirmed cases was 203. So estimated CFR back dating the denominator to Feb-12 is 1%. Assuming a denominator of 621, the CFR is 0.3%. if death s are lagging by 8-10 days (and con finned cases plateau), we should have a pretty good estimate of CFR for he entire group in another week or so. Will need to peel off the number of cases involving the crew member to get a better estimate of CFR in the elderly. These numbers are within the range we have been estimating . The 2,666 pass engers are similar in age (and likely in co-morbidities) to the population we see in a nursing home or residential ca re faci lity. The 1,045 crew are a proxy for a young healthy population. It will be important to look at the outcomes separately. One of the concerns is how a 'remake of this movie' could play out in similarly confined populations of elderly frail Americans. Here are the number s of long term care facilities /programs in the US that care for the frail elderly. A large number of loc ations and a large numbe r of residents /p articipa nts. I know that healthcare leaders were engaged yesterday, is anyone engaging this sector (long term care)? The healthcare leaders seemed more concerned about critical supply shortages (akin to the IV fluid shortage). Listening to them, it felt like their concerns seemed almost divorced from the threat ofCOVID. NIH-001495 Number of Number of Number of Number of Number of Facilities / Agencies I Beds Residents Participants Communities Centers Nursing Homes Residential Care Hospice Care Adult Day Care 15,600 28,900 1,700,000 996 , 100 1,300,000 811,500 4,300 4,600 1,400,000 286,300 Source: https ://www. cdc. gov/nchs /fas ta ts/nursing -home -care .htm The outbreak on the cruise ship should be the wake up call for leaders in long tenn care (and I would think healthcare overall). Here is a sununary of the cruise ship data (as of Feb 20) Date 20-Jan 25-Jan 1-Feb 3-Feb 5-Feb 6-Feb 7-Feb Event Cruise ship departs from Yokohama Japan 80 year old passenger disembarks in Hong Kong 80 year old passenger confnmed to have COVID-19 When results known , certificate of landing canceled and ship under quarantine. Tests for the virus would be administered to three groups : those with symptoms , those who got off in Hong Kong, and those who had close contact with the infected passenger. Ship arrives in port of Yokohama Japan 10 passengers and crew confinned + 31 more passengers and crew confirmed+ 30 more passenger and crew NIH-001496 Cumulative Number of Confirmed Cases 10 41 61 Cumulativ eNumber of Deaths Notes 8-Feb 10-Feb 11-Feb 12-Feb 13-Feb 14-Feb confirmed+ 9 more passenger and crew confirmed + 66 more passenger and crew confirmed+ 39 more passenger and crew confirmed+ 28 more passenger and crew confirmed+ 15 more passenger and crew confinned + 67 more passenger and crew confirmed+ 70 136 439 tested 175 492 tested 203 4 in ICU 218 713 tested 285 927 tested 73 asymptomatic; 1,219 tested 15-Feb 70 more passenger and crew confirmed+ 355 16-Feb 329 American evacuated from cruise ship (14 of the evacuees found to be +) 61 Americans remained on board 44 Americans remained hospita lized in Japan 369 17-Feb 85 more passenger and crew confinned + 18-Feb 19-Feb 167 more passenger and crew confirmed+ 2 deaths 454 1,723 tested; 19 serious ly ill 621 3,011 tested 621 Data by country is a bit sketchy Countiy Passengers us 434 330 256 241 78 35 Hong Kong Canada Australia UK Italy Total Confirmed Cases 58 32 46 6 NIH-001497 ICU Admissions Deaths 1 2 South Korea 14 Japan Subtotal 1,388 142 New virus cruise ship disembarks and kills two Japanese passengersin hospital February 20, 2020 11 :38 Two Japanese men and women in their 80s who were hospitalized and treated for the virus were killed on the 20th in a cruise ship passenger who was confirmed to be infected with the new coronavirus . This is the first t ime a cruise ship passenger has died and three peop le have been killed in the country . As of the 19th, 621 cruise ships out of approximately 3,700 crew members and passengers on the cruise ship where outbreaks of the new coronavirus were confirmed were confirmed. Accord ing to government offi cials, two of them, a 87-year-old man and an 84year-ol d woma n, died on the 20th. Both were Japanese and had a basic illness and were confirmed to have been infe cted w ith the virus, so it was said that men were hospitalized on the 11th of this month and women on the 12th to be treated. This is the fir st time a cruise ship passenger has died . In addit ion, three people have been killed in Japan, following th e death of a woman in her 80s living in Kanagawa Prefecture on the 13t h of this month. Sent from M a il for Windows 10 From: Carter Mecher Date: Wed nesday, February 19, 2020 10:05 PM To: Richard Hat chett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)(6); Dodgen , Daniel (OS/ASPR/SPPR) ; DeBord. Kristin (O5/ASPR/SPPR ); Phillips. Sally (O5/ASPR/SPPR) ; David Marcozzi; Hepburn. Matthew J CIV USARMY(USA); Lisa Koo nin; Wargo M ichael; Walters. William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander; EVANS,MARIEFRED; NIH-001498 Callahan. M ichael V.,M .D.; CbH6J Johnson, Robert (0S/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (0S/ASPR/ 10) ; Dean, Char ity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in. Gregory J (b)(6) '; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON. THOMAS; David Gruber CbH6J; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ------- - ----------- More puzzle pieces. Italy https: //protec t2.fireeye.com /url?k =e5d0524 7-b9844b3b -e5d063 780cc47adc5 fa2el6553f827677d60&u=htt ps ://www .joumalgazette .net/new s/wor ld/202 002 16/ g uarantine -ends- for-germans-italy-to-fly -citizens -from-s hip Italy plans to evacuate 35 Italians from the cruise ship • 25 Italian crew members (including the ship's captain) • 15 passengers UKhttps: //www .telegraph.co.uk/g lobal -health/sc ience -and disease /coronav irus-news -uk- china-s ingapore-death-to ll-Jatest / UK plans to evacua te British passengers Friday 2/21 78 British passengers on board 4 confirmed COV ID the Fore ign Office 2 passeng ers on board say they are infect ed Hong Kong https ://www .japantimes.co .jp/news/2020 /02/ 16/nationa l/science health/ canada-evacuat e-passenge rs-coro navirus-covid l 9-diamondprincess-cruise-s hip/ There are around 330 Hong Kong resident s on board, including 260 holding Special Administrative Region of Hong Kong passpo1ts and roughly 70 people with foreign ones . NIH-001499 South Korea https ://www. japantime s.co . jp/news/2020/02/1 8/nationa l/science hea lth/south- korea-evacua te-diamo nd-princess / The South Korean government is sending a presidential plane to Japan on Tuesday afternoon to evacuate several citizens on a coronavirusstricken cruise ship docked in Yokohama, a government official said Tuesday. 14 South Koreans - nine passengers and five crew members Canada https ://www . japantimes.co . jp/news/2 020/02/18/nationa l/scienceheal th/ cana da-diamond-princess -covid 19/ Global Affairs Canada had confinned that 32 out of 256 Canadians on the ship had tested pos itive . Canadian passengers are set to be evac uated from the virus- hit boat soon, passengers will be screened before boarding the evacuation aircraft , and those who exhibit symptoms of COVID-19 will be transferred to the Japanese health care system ,Australia https: //www .news.com.au/ travel /travel-updates/healthsafety/ unusua l-resc ue-fli gbt-ahead-for-aus tralian-evacuees -of-thed iamond-pr ince ss/news-story/ 564e590 bec70b 7182 5c897 df85d0bc24 Austra lia evacuated passengers from the cruise ship today. • • • • ~180 evacuated 15 declined evacuation 36 confirmed COVID hospitalized in Japan 10 newly confirmed had to stay behind So there were a total of ~241 Australians aboard the ship; 46 tested + (19%) The story from Australia sounds familiar (see below). NIH-001500 Australian cruise passengersarrive to Darwin after Diamond Princess virus outbreak ordeal Feb 20 A rescue mission of Australian cruise ship passengers from Japa n has officially landed in Darwin, but the ilight wasn't free from drama. Thousand s of people sharing toilets, pools and buffets - is thi s the petri dish of the sea? The Qantas coronavirus rescue flight, carrying about 180 citizens and permanent residents on board from Japan, has landed in Australia. Qantas flight 6032 touched down in Darwin at 8. 11am local time, after being slightly delayed from takeoff our of Haneda. The last -minu te drama hit the rescue mission when 10 Aus tralians, who were set to leave the coronavirus-hit Diamond Princess ship and head to the airport , were told they had tested positive to coronav irus and had to stay behind. About 180 citizens and permanent residents , who have spent the past fortnight on the quarantined cruise ship off the coast of Japan, had taken up the Federal Government' s offe r of a seat on the repatriation flight to Austra lia. They join another 36 Australians who contracted coronavirus on the Diamond Princes s and are being treated in Japan. About 15 of their rel atives declined the offer of repatriation to stay with them. The Australians on board will be screened for coronavirus five times before they are taken to a quarantine facility at Howard Qantas boss Alan Joyce praised the crew who took part in the repatriation flight as well as two previous Qantas chartered flights that broug ht Austra lians home from virus epicent re Wuhan . "It took literally thousands of hours to plan complex operations like these," Mr Joyce said at t press conference today. "T he crew were all vo lunteers and they did us proud ." NIH-001501 Yesterday , Australians who were cleared to finally disembark the Diamond Princess were driven by bus to Haneda Airport for the chartered flight home. They first needed to pass a health check to receive an approval of disembarkation notice by Japanese quarantine officials. They were then screened several more time s before they could board the Qantas 74 7. On the plane , they had no contact with Qantas crew, who remained upstairs for the flight. Food for passengers was already waiting for them at their seats when they boarded. If they passed the latest health check, they would have been given "approval of disembarkation" notices by Japanese quarantine officials , which grant them permission to enter Japan. From Yokohama Po1t, where the ship was docked, they boarded buses to Haneda Airport. Brisbane student Tehya Pfeffer , 18, who has been quarantined on the Diamond Prin cess with her grandmother Cathy, was among them. "At 10.30am (local time, 12.30pm AEDT) we will start to be screened and given luggage tags and wrist bands," Ms Pfeffer told news .com.au yesterday. "At 5pm we have to have our luggage put outside, and at 6pm we will disembark the ship and go through a makeshift customs . This is where we use our wrist bands. "And then we will take a bus to the airport and at around 12am Thursday we will fly to Darwin." On the evacuation flight , cabin crew would not be making direct contact with evacuees . Meals were already waiting for passengers at their seats when they boarded, and Qantas staff remained upstairs. All those retw·ning to Austra lia on the Qanta s flight will spend two weeks in quarant ine at the Howard Springs facility, in add ition to the two weeks in lockdown they've had on the ship. NIH-001502 Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)( ; Dodgen. Daniel (OS/ASPR/SPPR); DeBord, Kristi n (OS/ASPR/SPPR); Phillips. Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michael ; Walters. Will iam (STATE.GOV): HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6) Johnson, Robert (OS/ASPR/BARDA); Yeskey, Kevin; (b)(<;>:w, Gary (0S/ASPR/BARDA) ; Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/10) ; Hame l, Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ; Borio. Luciana ; Hanfling, Dan; McDonald. Eric; Wade, David ; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Gruber (b)(6) KAUSHIK, SANGEETA; Nathan iel Hupert -------- ----------Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start South Korea cases are taking off. S. Korea reports 31 more cases on 2/20; total now at 82 Singapore, Hong Kong , Japan, and South Korea are the new front lines. Matt er of time befo re travel from those areas will raise concerns. Sent from Mai l for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 4:45 PM Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Was listening to the discus sion today. There was a discussion about the shortages of PPE . There was also discussion re N PIs, but I'm not sure that most folks appreciate that the NPls that have been arrayed as part of the TLC strategy to reduce disease transmission in the community NIH-001503 can be leveraged to create safer compartments or spaces by shunting disease toward the home. By implementing these interventions, one could reduce the likelihood of disease in workplaces (by home isolation and home quarantine-- keeping sick employees at home and keeping employees who are well but potentially infected because someone is sick in their household, at home). Adding in other social distancing measures including social distancing at work, helps to reduce community transmission (adds additional protection to the workplace). The consequence is shunting disease to the home --120 M different compartrnents in the US, and making the workplace the safe place. That is potentially very important for critical infrastructure. The answer is not PPE for these employees. And why would we expect that employees in these sectors would have any better IPC with the use of PPE than we saw with staff on the Diamond Princess? Healthcare is a key critical infrastructure. It is different from the other sectors in that it will be attracting patients with COVID like a magnet. It is hard to imagine how one could makes healthcare a safe workplace. But it is only hard to imagine how one could do that unless you begin to look a little closer at the different components of the healthcare system and the roles each component might play during this pandemic . To illustrate this, I took a stab at developing a conops or roadmap to look at the various pieces of the healthcare system. The shunting of disease is really fractal. Just as we can look at shunting disease across a community into one compartment (the home) to make other compartments safer, we can do the same within our healthcare systemshunt disease to the acute care area where COVID patients will be conce ntrated. What are the strategies to do that? This conops is notional. It is purposely designed for a severe outbreak with severe disease and assumes that the hea lthcare system must somehow continue to limp along and continue to care for the background disease we see during normal times (strokes , AMis, fractures and trauma, appendicitis, other serious infections, CHF, diabetic emergencies, psychotic episodes, preeclampsia, complicated deliveries, end stage renal disease and dialysis, etc.) as well as sustain outpatients with chronic conditions that require monitoring and care to keep them well and out of the ER and out of the hospital. NIH-001504 Sent from Mail for Windows 10 From: (b)( Date: Wednesday, February 19, 2020 2:36 PM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane; (b)(6); Dodgen , Dan iel (OS/ASPR/SPPR); DeBord. Krist in (O5/ASPR/SPPR); Philli ps. Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn . Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters , Wil liam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARl EFRED; Callahan, M ichael V.,M .D.1 (b)( ~ ; Johnson , Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/S PPR); Hassell , David (Chris) (OS/ASPR/IO); Hame l, Joseph (OS/ASPR/1O); Dean, Char ity A@CDPH; Lawle r, James V; Kadlec, Robert (OS/AS PR/ 1O); "M art in, Grego ry J (b)(6)..,.· Borio. Luciana; Hanfling, Dan; McDona ld. Eric; Wade. Qilld.Q.; TARANTINO, DAVID A ; W ILKINSON, THOMAS; David Gr uber (b)(6]; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start _______ ---------- Update for South Korea (see attached) 51 cases; l child Colombia confirms first case of Coronavirus citizen on Japan cruise ship February 17th, 2020, 09:06 AM @Stats Alerts BREAKING: Colombia conf irms fir st case of Coronaviru s Colombia confirm s fir st case of coronavi rus: citizen wa s on a Diam ond Princess cruise Sent from Mail for Windows l 0 From: Carter Mecher Date: Wednesd ay, February 19, 2020 10 :05 AM NIH-001505 To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane ; (b)(6); Dodgen, Daniel (0S/ASPR/SPPR); DeBord , Kri sti n (0S/ASPR/SPPR); Phillips, Sally (0S/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wa rgo Michae l; Wa lters, W illiam (STATE.GOV); HARVEY, MELISSA; WO LFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callah an, M ichael V.,M .D.; (b)(6J Johnson , Robert (0S/ASPR/BARDA) ; Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell. David (Chris) (0S/ASPR/ I0) ; Hamel, Joseph (OS/ASPR/10 ); Dean, Charity A@CDPH; Lawler, James V; Kadlec. Robert (0S/ASPR/10 ); 'Mart in, Gregor y J (b)(6) ' ; Borio, Luciana ; Hanfling, Dan; McDonald, Eric; Wade, ~ TARANTINO, DAVID A; W ILKINSON, THOM AS; David Grub er _________ Cb _ >_<6J _ ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start Update on HK (65 cases; no children) and Singapore (84 cases; 49 currently hospitali zed/4 in ICU; still only 4 children (2 asymptomatic /2 hosp ita lized). Sent from Ma il for Windows 10 From: Carte r Mecher Date: Wednesday, February 19, 2020 8:20 AM To: Richa rd Hatche tt ; Dr. Eva K Lee Cc: Tracey McNamara ; Caneva, Duane ; (b)(6J; Dodgen, Danie l (OS/ASPR/SPPR); DeBord, Kristin (OS/ASPR/SPPR); Phill i ps, Sally (0S/AS PR/SPPR); David Ma rcozzi; Hepburn. Matt hew J CIV USARMY (USA); Lisa Koon in; Wa rgo Michae l; Wa lte rs, W illiam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman , Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.; (b)(6); Johnson, Robert (OS/ASPR/BARDA); Yeskey. Kev in; Disbrow. Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SP PR); Hassell, David (Chris) (OS/ASPR/I0) ; Hamel. Joseph (OS/ASPR/10) ; Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10); 'Mart in, Grego ry J (b)(6) ' ; Borio, Luciana; Hanfling, Dan; M cDona ld, Eric; Wad e, David; TARANTINO, DAVID A; W ILKINSON, THOMAS; David Grube r _________ Cb _ >_<6J _. ,; KAUSHIK, SANGEETA; Nathan iel Hupe rt ------- - Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start NIH-001506 As of yesterday, there are 251 Canadians on board the Diamond Princess , of whom 34 have tested positive. https://global news.ca/ news/6567907 / c...hi p-canadia ns/ Canada wa lks back expected departure date for evacuees of Japanese cruise ship By Staff The Canadian Press Posted February 19, 2020 7:47 am Updated February 19, 2020 7:49 am Global Affairs says the departure date for a plane that w ill carry Canadians home from a coronavirus-stricken cruise ship in Japan is yet to be confirmed. Spokeswoman Barbara Harvey says the departure wil l be settled once final arrangements are made with the Japanese government and the cruise ship company . A news release from the company operating the Diamond Princess cruise ship says the Canadian flight has been "shifted 11 to early Friday morning . Sent from Ma il for Windows l 0 From: Carter Mecher Date: Wednesday, February 19, 2020 8:09 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey M cNamara; Caneva, Duane: (b)(6): Dodgen. Dani el (OS/ASPR/SPPR); DeBo rd, Kristin (O5/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David M arcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mich ael; Walters, Will iam (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.f (b)( 6)1 Johnson. Robert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary (OS/ASPR/BARDA); Redd, Johnt(OS/ASPR/SPPR); Hassell, David (Chr is) (OS/ASPR/IO); Hame l. Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawle r, James V; Kadlec. Robert (OS/ASPR/1O); 'Mart in, Gregory J .__________ Cb _)_( _,,_, '· Borio, Luciana; Hanfli ng, Dan; M cDonald, Eric; Wad e, David; TARANTINO, DAVID A; WILKINSON, THOMAS; David Grub er (b)(~; KAUSHIK, SANGEETA; Nat haniel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ------------ NIH-001507 621 cases on cruise sh ip (17% of the passenge rs and crew have been infected). https://www.channe lnewsasia.com/news ...it ive-12450498 79 more people test positive for COVID-19 on Diamond Princess cruise ship 19 Feb 2020 06:21PM (Updated : 19 Feb 2020 06 :30PM) TOKYO: An additional 79 cases of coronavi rus have been discovered aboard the Diamond Princess cruise ship in Japan, the health ministry said Wednesday (Feb 19), bringing the total to 621. Sent from Mai l for Windows l 0 From: Carte r Mecher Date: Wednesday, February 19, 2020 6:06 AM To: Richard Hatchett ; Dr. Eva K Lee Cc: Tracey McNama ra; Caneva, Duane; (b)( ; Dodgen, Daniel (OS/ASPR/SPPR); DeBord, Kri stin (OS/ASPR/SPPR); Phillips, Sally (OS/ASPR/SPPR); David Marcozzi ; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michael ; Walters, William (STATE.GOV); HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan. M ichael V.•M .D.; (b)(6); John son, Robert {OS/ASPR/BARDA); Yeskey, Kevin; Disbrow, Gary {OS/ASPR/BARDA); Redd, Johnt{OS/ASPR/SPPR); Hassell, David {Chris) (OS/ASPR/1O); Hamel, Joseph (OS/ASPR/1O); Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/1O); 'Mart in, Gregory J ( (b)( 6Yil:_; Borio, Luciana; Hanf ling, Dan; McDonald, Eric; Wade, David ; TARANTINO, DAVID A; WILKINSON, THOMAS; David Gruber (b)(6) ; KAUSHIK, SANGEETA; Nathan iel Hupert Subject: RE: Red Dawn Breaking , COVID-19 Collaborative, Feb 16 start ---------- -- I saw a news s101y yesterday (WashPost) that testing was comp leted. So we should know in the next coupe of days. A lso saw a story abou t the 100 or so Americans left behind (44 in hosp itals and 61 who declined evacuation) . https://mainichi.jp /engl ish/articles/20200219 /p2g/00m/0in/028000c NIH-001508 Hard to find data on the stah 1s of those still ho spita lized in Japan. James made a very important point yesterday. Altho ugh the passengers are elderly (2,666 passengers) , the crew membe rs are relati vely young (1 ,045 crew members). James also expected the attack rates to be very high among the crew member s (they were housed together in a relatively small space aboa rd the ship, perfect condit ions for explosive disease transmission). So this combined data on passengers (elderly) and crew (young and healthy) will be invaluable in terms of helping understand seve rity . I wou ld think that Japan also realizes how invaluable this data is. Japan will be in the best position to assess the impact on the crew, since they will know the results oflab screening and hospitalization of all + crew members (as well as the monitoring qua rantine of the rest of the crew over the next 14 days). But now that the passengers are being dispersed, it will be important for several nations to share the data on these passengers - it is really our best chance to understand severity (would need collabo ration of the US, Canada, Australia, Ho ng Kong, Japan). Sen t from Mail for Windows 10 From: Richa rd Hat chet t Date: Wednesday, February 19, 2020 4:47 AM To: Dr. Eva K Lee; Carte r M eche r Cc: Tracey McNama ra; Caneva, Duane; (b)(6) Dodgen , Daniel (OS/ASPR/SPPR); DeBord, Kri st in (OS/ASPR/SPPR); Philli ps, Sally (OS/ASPR/SPPR); David Marcozz i; Hepburn, M att hew J CIV USARMY (USA); Lisa Koon in; Wa rgo M ichae l: Wa lte rs. Will iam (STATE.GOV): HARVEY. MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS, MARIEFRED; Callahan, M ichael V.,M .D.1 (b)(6) · Johnson, Ro bert (OS/ASPR/BARDA); Yeskey, Kevin; Disbrow , Gary (OS/ASPR/BARDA) ; Redd, Johnt (OS/ASPR/SPPR); Hassell, David (Chris) (OS/ASPR/ 10) ; Hamel, Joseph (OS/ASPR/ 10) ; Dean , Charity A@CDPH; Law ler, James V; Kadlec, Robert (OS/ASPR/10); 'M art in, Grego ry J (b)(6) '; Borio, Luciana; Hanfli ng, Dan; McDonald, Eric; Wade, -------David; TARANTINO. DAVID A; W ILKINSON. THOM AS; David Grube r (b)(6); KAUSHIK, SANGEETA; Nat haniel Hupert ----------· Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start NIH-001509 I understandfrom contacts at WHO that Japan is testing everyone on the Diamond Princess , so we should have a complete accounting of that closed population (and thus a nice dataset to inform severity estimate s). From: Dr. Eva K Lee Date: 19 February 2020 03:54 To: Carter Meche rr------Cc: Tracey McNamara I ---------- (b)(6) Cb =>=c6J =~ (b)(6))>;Caneva, Duane Cb)(6))>;Richard Hatchett ======:::,~;-::--:-(b)(6)jDodgen, Daniel (OS/ASPR/SPPR) (b)(~ DeBord, Kristin (OS/ASPR/SPPR) =======;~::,;--~ (b)(6) ]>; Phillips, Sally (OS/ASPR/SPPR) =======~':;;:' ---------~~ CbH6)] David Marcozzi CbH6)]>; Hepburn, Matthew J CIV USARMY (USA) CbH6J>; Lisa Koonin f (b)(6)J>; Wargo Michae l CbH6)}>; Walters , William (STATE.GOV) -:.======= (b '=== )='(6J '5i' t---:·H -:-'. A~R-:-'. V:::: EY -:-,-:--: M ELISSA! CbH6))>; ======::::!...-~ ~ -------- WOLFE, HERBERT ! -------'=====; CbH6))> ; Eastman, Alexander (b,:::: )(~(6)) ,;:>-; =EV -:-A :-:N -:-S :-, -:M-:-'. A:-:R ~IEFRED (b)(6)j; Callahan, Michael V.,M.D. (b)(6)}; (b)(6) , Johnson, Robert (05/ASPR/BARDA) CbH6))>; Yeskey, Kevin! (b)(6)j --------,:..;____ -=======~~~,.......----Disbrow, Gary (OS/ASPR/BARDA) CbH6J>;Redd, .,,:.... __ .:.......::==:::::::;,:;;------:-:--Johnt (OS/ASPR/SPPR) (b)( >; Hassell, David (Chris) (OS/ASPR/I0) (b)( >; Hamel, Joseph (OS/ASPR/10) (b)(6)>; Dean, Charity A@CDPH ~======:=!!'======..::::-..::::-..::::-_-_-~= -------~~ (b)(6))> ; Lawler, James V (b)(6)}>; Kadlec, Robert (OS/ASPR/10)1 (b)(6J:>; 'Martin, Gregory J (b)(6))Borio, Luciana (b)(6),>; Hanfling, Dani CbH6) 1>; McDonald, Eric (b)(1> )J>; Wade, David I (b)(6b; CbH6))>; WILKINSON, TARANTINO, DAVID Ar Cb)(6)]; David Gruber THOMAS( =======~= ---------- '-:-:---:--::-:'.::-:.:========='c~;;---:--:--:--:(b - )_(6>: _,..... v>; KAUSHIK, SANGEETAI (b)(6)_ ; Nathaniel Hupert (b)( 6)j ----!:====~=":"---- Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start Just talked to a lab director in Hong Kong U. They tested 3,600 passengers and crews on World Dream in 24 hours , all using the definitive RT-PCR test. The tests were performed in government labs . They disembarked everyone after 3 days (a ll came back negative). And they are still performing contact tracing and monitoring on all at the moment. NIH-001510 old news: https ://www .scmp.com/news /hong -kong/healt henvironmen t/article/304 97 14/coronavi rus-3600 -passe ngers -and-crewmembers For surveillance , regional hospitals do an initial screening , then suspected cases are tested by a governmental lab for confirmation. Schools are still closed for another month. (b)(6) mobile: ----- (b)(6) Sent with ProtonMa il Secure Emai l. ------- Original Message ------On Tuesday , February 18, 2020 7:56 PM, Carter Mecher (b) < ·> wrote: -------- Japan inching toward mitiga tion Abe urges people with coldlike symptoms to avoid work, school Today 06:30 am JST 24 Comments NIH-001511 TOKYO Prime Ministe r Shinzo Abe on Tuesday advised peop le across the country not to go to work or schoo l if they develop cold-like symptoms, as the country grapples with the spread of a new coronavirus origina ting in China. Workplaces in the country, known for their long hour s, need to encourage people to take days off without hesitation if they do not feel well , Abe said. "The first thing that I want the people of Japan to keep in mind is to take time off school or work and refra in from leaving the hou se if they develop cold-like symptoms such as fever," Abe told a meeting of a government task force on the viral outbreak. Te leworking is an "effect ive alternative" to help prevent the viru s from spreading fmther, Abe said . He made the remarks as the governmen t is scrambling to contain the virus that originated in Wuhan, with more people with no obvious link to Ch ina gett ing infected in Japan. The global outbreak of the disease called COVID -19 has prompted some even t organizers in Japan to rethink their plans for hosting mass gather ings. The number of confi rmed cases in Japan has topped 600, including over 500 passengers and crew on the Diamond Princess , a quarantined cruise ship docked at Yokohama near Tokyo with more than 3,000 confined. The steady rise in infections in various pa1ts of Japan has raised public concern , prompting the health ministry to ask people who develop symptoms such as a temperature of 37.5 C or higher fo r at least four days to cons ult loca l health care centers and go to designated hospital s. The period is set shorte r for the elderly , those with underlying condi tions and pregnan t women. As Tokyo and othe r major cities in the country are notor ious for packed rush -hour trains, commute rs have been encouraged by a government panel of medical experts to go to work earlier or later than usua l as the risk of infect ion is increased in crowds . NIH-001512 On Tuesday, Fujitsu Ltd and Hitach i Ltd said they are expa nding teleworking , though Japane se companies overall have been slow to introduce it. Sent from Mail for Window s 10 From: Tra cey McNama ra Date: Tuesday , February 18, 2020 4:38 PM To: Dr. Eva K Lee ; Canev a, Du ane Cc: Cai1er Mecher ; Richar d Hatchett ; (bH6); Dodgen, Daniel (OS /ASPR/SPPR t DeBord , Kristin {OS/ASPR/SPPR ): Phillips. Sally (OS/ASPR /SPPR) : David Ma rcozzi ; Hepburn . Matthew J CIV USARMY (USA) ; L isa Koonin ; Wargo Michae l; Walter s, Will iam (STATE.GOV) ; HARVEY . MELISSA ; WOLFE, HERBER T; Eastman. Alexander ; EVANS, MARIE FRED ; Callahan, Michael V.,M .D.; (b) (6) Johnson . Robe rt (OS/ASPR/BARDA) : Yeskey. Kevin ; Disbrow. Gary (OS/ASPR/BARDA ); Redd. Johnt(OS/ASPR/SPPR ) : Hassell, David (Chris) (OS/ASPR/1O) ; Hame l, Jos eph (OSI ASPR /1O) : Dean, Charity A@CDPH ; Lawler, James V; Kadlec, Robe rt (OS/ASPR/1O) : 'Martin, Gregory J (b)(6) •; Borio, Luc iana; Hanfl ing. Dan ; McDon ald, Eric; Wade, David ; TARAN TIN O, DAVID A ; \VILKINSO N, THOMAS ; David Gruber (bH6); KAUSHIK, SANGEETA ; Nathaniel Hupert ------- ------------------------ ---------- Subject: RE: Red Dawn Br eaking, COVID -19 Collaborat ive, Feb 16 sta1t I must be psychic. This just came out. Like I said - Oxford Nanopore NIH-001513 Sequencers are being sent to China! Tracey https://protect2.fireeye.com/url? k=0a860669-56d21f150a863756-0cc47adc5fa24fc7adc96dfbde59&u=https://glo balbiodefense.com/newswire/ox ford-nanopore-sequencershave-left-uk-for-china-tosupport-rapid-near-samplecoronavirus-sequencing-foroutbreak-surveillance/ To: 'Caneva, Duane' -- CbH > · Carter Mecher ' ; Richard Hatchett Cb><6l; Dr. Eva K Lee (b)(6) Cc~ Dodgen, Daniel (0 /ASPR/SPPR) ________ Cb> _<6); DeBord, Kristin (OS/ASPR/SPPR) Cb> <6) ; Phillips , Sally (OS/ ASPR/SPPR) CbH6); David Marcozzi CbH6) > ; Hepburn , Matthew J CIV USARMY (USA) CbH6) • Lisa Koonin ..-----' Cb> <6)>; Wargo Michael Cb>< ,• Walter s ' > ---------- __________ NIH-001514 William (STATE .GOV) _________ Cb _>< _6J; HARVEY, MELISSA Cb><6J· WOLFE ' ' CbH6),. , HERBERT Eastman, Alexander Cb><6)>; EV ANS, MARIEFRED (b)(6) >. ____________ ------------------------Callahan , Michael V.,M .D. ' (b)(6) Johnson , Robert (OS/ASPR /BARDA) Cb>< >- Yeskey Kevin ' ' Cb><6)>; Disbrow, Gary (OSI ASPR/BARDA) _______ Cb> _<6J>; Redd, John (OS/ASPR/SPPR) Cb><6)>; Hassell, David (Chris) (OS/ASPR/IO) _______ Cb> _<6); Hamel, Joseph (OS/A SPR/1O) Cb>< > · Dean Charity ' ' CbH6J>Lawler , r--, CbH6); K adl ec, James V (b)(6) Robert (OS/ ASPR/1O) 'Martin, Gregory J Cb> <6) Cb>< > · Borio Luciana ' ' Cb>< ; Hanfling, Dan Cb><6J p ; McDonald , Eric CbH6) }>. Wade David ' CbH6); TARANTINO ,' DAVID A Cb><6J> • -------------' WILKINSON, THOMAS Cb>< >· David Grub er Cb>< ) ' Cb><6) p-; KAUSHIK, SANGEETA Cb><6) t ; Nathaniel Hupert Cb>< Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start ----- ---- NIH-001515 Hello all - Clearly , the most important thing of all is a reliable , real-time diagnostic test that can differentiate between flu and COVID-19. CDCs test kits were recalled because states said they were not working. Now they have to remanufacture the faulty reagent. How long will that take? If and when more kits are available , will they be available in sufficient quantity that all health care providers will have access? In all of this, I have not heard anyone talk about the Nanopore MinION technology that has been used for Ebola. What gives??? It is field deployable and can be run in-house. Hospital labs can run thousands of samples at once. It gives results of all viruses, bacteria, protozoa , fungi, in 2 hours. We all know this technology is quite promising. Why aren't we going gangbusters to validate this rapid technology and get it to all diagnosticians? If ever there was a time to invest in a diagnostic technology , this is it! Tracey NIH-001516 From: Dr. Eva K Lee > (b)( Date: Tuesday , February 18, 2020 1:06 PM To: Caneva, Duane ---------- Cc: Carter Mecher (b) (6) Richard ; Tracey McNamara Cb)(6) ; _________________ Hatchett CbH6);> (b) ((ij•, Dodgen, Dan iel (OS /ASPR/SPPR) Cb)(6) > ; DeBord, Kristin (OS/ASPR /SPPR) Sally (OS/ASPR/SPPR) Cb)C6)> ; Marcozzi Matthew J CN USARMY (USA) Cb)(6); Phillip s, David Cb)C6); Hepburn, ------------------- ---- >; L isa Koonin ; Wargo Michael (b)(6) Walters , William Cb)(6) ; HARVEY , CbH6)> ; WOLFE, Cb)( (STATE . V) MEL ISSA HERBER Cb)(6); Eastman, ______________ ;EVANS, (b)( > ,· Callahan, Michael V .,M.D . (b)(6) Cb)(6) Robert (OS/ ASPR/BARDA) Yeskey, Kevin (OS/ASPR /BARDA) Johnt(OS / ASPR/SPPR) David (Chris) (OS/ASPR/ IO) Hame l, Joseph (OS/ASPR/ 1O) ----....,, Dean, Charity A@CDPH Lawler, James V ....,..._,..., Robert (OS/ ASPR/ 1O) Gregory J Borio, Luc iana (b) (6) . (b)(6) ..-----' ; Disbrow, Gary Cb> (6) ; Redd, Cb) (6) ; Hassell , (b)(6) > ; (b)( (b)(6) p ; Cb)<6Y du>· Kadlec =-Cb) ~'C6)v ~ > ; 'Martin, ' (b)(6) Cb)C ; Hanfling , Dan McDonald, Eric Cb) (6) ; Wade, David (b)(6) > ; TARANT INO , DAVID A Cb)C6)> ; WILKINSON, , (b)(6)• (b)(6) > ; THOMAS Johnson, --- ___ (b) (6)) NIH-001517 ========~ Cb><6J; KAUSHIK, SANGEETA Cb)(6); Na thani el Hu pert (b) ~(6) ~- Subject: RE: Red Dawn Breaking, COVID-1 9 Collaborative, Feb 16 start Carter, Just listened in to our state COV ID-19 response effort updat e. Georgia has no COVID-1 9 cases yet , and hence they remain in the conta inment period where they place medium-risk individuals on supervised monitoring of home quarantine, advise them to take temperature daily and report any respiratory symptoms (24/7). Educate them not to show up in ED, or any place without facilitation. To avoid potential disease spread, they are advised to remain at home. The next stage will be mitigation when a confirmed case is reported. That will initiate the pandemic planning and community-based NPI will be considered. This includes social di stancing -- telework , teleclass , etc. I assume at cities where there are confirmed local COV ID- 19 cases, the public health leaders have already begun the mitigation phase now and hence are practicing some degree of social distancing and rolling out telework, and various strategies to protect health in the population and to maintain business con tinuity already. Is that true or they are still wa iting to execute their operations? There are not many tests needed here in Georgia. But rapid robust and reliable testing kits (Tracey's reporting of current bottleneck) remain critical in all communities with positive cases. If we have such mean s, test ing can also be conducted (sampli ng) on some flu-like cases at strategic selec ted cities also. NIH-001518 ------- Original Message ------On Tuesday , February 18, 2020 2:20 PM, Dr. Eva KLee (bH > wrote: --------- Duane, Yes. (asymptomatic or mild symptoms) this is the worry at the very start, and it remain s the most critical. Hence even 1% of infection for us -- can balloon out of proportion and we can't handle . Shedd ing not only during infection period, bur also post-recove ry. It's a very long time line that we have to deal with. Then you have all the university siudents . Students travelled to China and came back to school, they asked hea lth service if they needed to quaran tine or take any actio n, theadvice -- no need. Those are missed opportunities. Again, seasonal influenza affects 8-10% Americans, 0.7% of those infected requir ed hospitalization , and morality is roughly 0.1 %. So it is easy to "calculate" all these numbers backwards ... So 20% ofCOVID19 infected may need hospitalization, mortality is 10-30 times higher than seasona l flu. How much can we tolerate before anyone would spring into action? Keep in mind, some begin to infect rapidly upon contracting the virus, the incubat ion is so short (and so long) and infectious too dming that period (with much being unknown). Ca1ter, I think you will expect hetero geneous approaches from different communit ies in the overall response strategy, since it depends on the socia l setting and the demographics and more imp ortant ly the local resources. We have to optimize for sure. NIH-001519 ------- Original Message ------On Tuesday , February 18, 2020 1:51 PM , Caneva, Duane Cb)(6) wrote: Seems to me a big challenge will be asymptomatic or mild symptoms in kids, spread through the schools, shed to parents who staff both categories acute and non-acute care clinics. If there are several days of asymptomatic shedding, how do you prevent spread to the vulnerable, high risk patients in each category? Wi H mi ld symptoms drive complace nt compliance? From: Carter Mecher (b)(6) > Date: Tuesday , February 18, 2020 1:32 PM Subject: RE : Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start CAliTIO~: This email originated from outside of OHS. DO NOT click links or open attachment s unless you recognize and/o,r trust the sender. Contact your component SOC w ith questions or concerns. NIH-00152 0 My thinking is evolving in terms of healthcare system response. Initially I described how I would refocus the outpatient clinics away from COVID care and leverage the NPis of isolation and quarantine to help keep the workplace safe (for the clinic staff and other patients) rather than a strategy that employs PPE. I would only use the outpatient clinic staff to help with telephone /home care support of those patients under home isolation or home quarantine--to help with compliance /adherence to isolation and quarantine, monitoring their health, and optimizing the care of their other chronic medical conditions (to keep them out of the ER and the hospital). But as I thought more about this, it occurs to me that this can be generalized beyond outpatient clinics. I would think about dividing our healthcare system into two big pieces: ( 1) acute care (EDs, acute inpatient care, critical care); and (2) non-acute care including outpatient clinics (PC/Family Practice , pediatrics , OB/GYN, medical specialty, surgical specialty , dental, mental health, rehab, etc.), as well as other inpatient areas (inpatient mental health, substance abuse, nursing homes , hospice care, memory care, assisted living, etc.). Inpatient surgery (and I suppose labor and delivery) is part of acute care, but for this outbreak, it probably best belongs bundled with the other non-acute inpatient NIH-001521 areas. I would anticipate that the tripwire for implementing NPis (community transmission), will also be the trigger for healthcare systems to dial down or tum off elective admissions (primarily surgical) to free up acute care and ICU/monitored meds. The most effective way to protect these nonacute areas is by shunting potential COVID pat ients away from these areas and either providing this type of care while the patients is hospitalized in acute care or thru telephone care/home care for patients with mild illness receiving care at home. And the most effective way to shunt these patients away from non-acute care areas is thru the implementation of early and aggressive NPis of isolation of the ill and home quarantine of household contacts (and not fit testing the world and passing out PPE that we don't have) . Sent from Mail for Windows 10 From: Carter Mecher Date: Tuesday , February 18, 2020 11:02 AM To: R ichard Hatchett; Caneva, Du ane; Tra cey McN amara; Dr. Eva K Lee ; (b)(6) (b)(6) ; Dodge n, --------Danie l (OS/ASPR/SPPR) : NIH-001522 DeBord. Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR /SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA) ; Lisa Koonin; Wargo Michael; Walters, William (STATE .GOV) ; HARVEY, MELISSA; WOLFE , HERBERT ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan, M ichael V .,M.D .; (b)(6) ------,------ Johnson, Robe rt (OSI ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gary (OS/ASPR/BARDA) : Redd, John (OS/ ASPR/SPPR) : Hassell, David (Chli s) (OS/ASPR/10) ; Hamel, Joseph (OS/ASPR/ 10) : Dean, Charity A@CDPH; Lawler, James V; Kadlec, Robert (OS/ASPR/10) : 'Martin, Gregory J (b)( ' ; Borio, Luciana; Hanfli:ng,Dan; McDonald , Eric ; Wade, David ; TARANTINO, DAVID A; WILKINSON , THOMAS; David --------Gruber (b) (6); KAUSHlK , SANGEETA ; Na than iel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More puzzle pieces re the cruise ship outbreak. • About 2/3rds of the passeng ers NIH-001523 have been tested so far (2,404 out of 3,711). • 61 Americans opted to remam onboard and not be evacuated. Japan has completed tests for all passengers and crew aboard the ship as of Monday, but the results for the last batch of tests aren 't expected until Wednesday, the day that the quarantine is slated to end. So far, results are back for 2,404 passengers and crew , out of the 3,711 who were on board the ship when the quarantine began on Feb . 5. Japanese Health Minister Katsunobu Kato said Tuesday that people who have tested negative for the virus would start leaving on Wednesday, but that the process of releasing passengers and crew won't be finished until Friday , according to the Washington Post. The remaining 61 American passengers on the DP who opted not to join the evacuat ion will not be allowed to return to the US until March 4, according to the American embassy in Tokyo. The governments of Australia, Hong Kong and Canada have also said they would evacuate passengers. NIH-001524 Elsewhere, Japan confirmed three more cases of the virus. This tim e, they were confirm ed in W akaya ma, a pr efec ture in eas tern Japan. Sent from Mail for Windows 10 From: Carte r Mecher Date: Tuesday, February 18, 2020 10:50 AM To: Rich ard Hatchett; Caneva , Duane ; Tracey McN amara ; Dr. Eva K Lee ; Cb) (6) ..,________ __>; Dodgen, Daniel {OSIASPR/SPPR); DeBo rd, Kristin (OSIASPR /SPPR) : Phillips, Sally (OSIASPR /SPPR) ; David Mar cozz i; Hepbu rn, Matthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walters. W illiam {STATE.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman, Alexander ; EV ANS. MARIEFRED ; Callahan, Michael V.,M .D .; (b)(6) ; Johnson, ------Robert (OSI ASPR/BARDA) ; Yeskey , Kevin ; Disbrow, Gary (OSIASPR/BARDA) ; Redd, John (OSIASPR/SPPR) ; Hassell, David (Chris) (OSI ASPR/10) ; Hamel, Jose ph (OSI ASPR/ IO) ; Dean. Charity A@CDPH; Law ler, James NIH-001525 V ; Kadlec, R obert (OSIASP R/1O): 'Martin, Grego ry J (b)(6l '; B orio, Lu ci ana ; H an fling , Dan ; M cDon ald, Er ic ; Wade , Dav id; TARAN TI NO , DA YID A ; WIL KINS ON, THOMAS ; Dav id Grube r --------- (b)(6) KAUS HIK , SANGEETA ; Nath aniel Rupe rt Subject: RE: Red Dawn Break ing , COVID-19 Co llaborative, Feb 16 start Maybe he was misquoted or it was a typ o- perhaps what was meant was 4 per 100 (and that would be a low estimate) Sent from Mail for Window s l 0 From: Richard Hatchett Date: Tuesday, Februaiy 18, 2020 10:45 AM To: Ca rter M echer; Caneva , Dua ne; Tra cey McNamara ; D r. Eva K Lee ; (b)(6) > ; Dodgen, Danie 1 (OSIAS PR/S PPR); DeBo rd, Kristin (OS/ASPR/SPPR) : P hillips, Sally (OS/ASPR/S PPR) ; Da vid '----'------..J- NIH-001526 Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koon in; Wargo Michae l; Walters , William (S TATE .GOV) ; HARVEY , MEL ISSA ; WOLFE , HERBERT; Eastman, Alexan der; EV ANS , MARIEFRED ; Callahan, Mic hael V .,M.D. ; (b)(6) Johnso n, -------Robe rt (OSI ASPR/BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OSI ASPR/SPPR): Hassel l, David (Chr is) (OS /ASPR/ 1O) : Hamel, Joseph (OS/ASPR/ 1O) : Dean , Charity A@CDPH ; Lawler, James V ; Kadlec, Robert (OS /ASPR/ 1O) ; 'Martin , Gregory J CbH '; Borio, Luci ana; Hanfling. Dan ; McDo nald, Er ic; Wade . David ; TARAN TINO, DAV ID A; WILKINSON, THOMAS ; David Gruber (b) (6)., ,__ --------- _________ KAUSHIK, SANGEETA; Nathanie l Hupe rt Subject: RE: Red Dawn Breaking, COVID -19 Co llaborative , Feb 16 start No te that 4/ 100,000 woul d imply that only 440 peop le have been infec ted. From: Carter Mec her (b)(6) NIH-001527 Date: 18Febmary202015: 26 To: Caneva, Duane (b)(6) Tracey McNamara Cb)(6) ; Dr. EvaKLee > ; Dodgen, -------Danie l (OS/ ASPR/SPPR) (b)(6) > ; DeBord , Kristin (OS/ASPR /SPPR) (b) (6).; Ph illips, Sally (OS / ASPR/SPPR) Cb)< > ; David Marcozzi -------- (b)(6) >; Hepburn, Matthew J CN USARMY (USA) (b)(6) >; Lisa Koonin -------Michael Cb)(6) ; Wargo )(6) Walters , William (STATE .GOV ) (b)( HARVEY, MELISSA (b)(6) >• , WOLFE,HERBERT (b)(6) Eastman, Alexander (b)(6) > ; EV ANS , MARIEFRED )(6) Callahan , Michael V. ,M.D. _________ ; Johnson, Robert (OS/ ASPRJBARDA) , (b)(6) > · NIH-001528 Yeskey, Kevin (b)(6) Disbrow , Gary (OS/ ASPR/BARDA) --------- Cb> (6) > ; Redd, John (OS/ASPR/SPPR) Hassell , ------David (Chris) (OS /ASPR / IO) Cb> (6) > ; (b) (6Ji; Hame l, Jos eph (OS/ ASPR/IO) CbH6) >; Dean, Charity A@CDPH --------- CbH>· ' Richard Hatchett (b)( >; (b)( ; Lawler, James V Kadlec , Robert (OS / ASPR/IO) (b)(6) 'Marti n, Gregory J (b)(6) ------ Luciana Hanfling, Dan (b)( McDonald, Eric (b)(6) ; Wade , David (b)( >; TARANTINO, DAVID A (b) (6) > ; WILKINSON , THOMAS (b)(6) David Gruber KAUSHIK , SANGE ETA ----------Nathaniel R upert (b)( (b)( Subject: RE: Red Dawn Break ing , COVID-19 Collaborative , Feb 16 start NIH-001529 > >· ' WHO estimates 80% of patient with COVID-19 have mild disease and recover; that implies that 20% have severe disease. WHO estimated that 14% develop pneumonia and 5% are considered critical. [We were estimating that 12% of cases needed hospitalization (so 88% did not) and 2% needed ICU care (with mortality of patients with pneumonia in the ICU generally between 15%-50% so a CFR of 0,3%-1.0%). Also noet his comment on sparing children. The latter comments are reminiscent of the early comments of public health leaders during the 1918 pandemic-always minimizing. I have no idea where an attack rate of 4 per 100,000 comes from.] https://www .channelnewsa sia.com /news/world/covid-19coronavirus -who-china -patien tsha ve-mild-disease-124450 10 GENEY A: The new novel coronavirus only causes mild disease for 80 per cent of infected patients, said the World Health Organization on Monday (Feb 17). Speaking to reporters , WHO chiefTedros Adhanom Ghebreyesus said that 14 per cent of patients would have severe diseases such as pneumonia. "Around five percent of cases are cons idered critical with possible multi-organ failure, septic shock and respiratory failure and, in some cases, death," he added. NIH-001530 Tedros also said there were "relative ly few cases" among children and more research was needed to understand why. The WHO chief also warned against "blanket measu res" over the novel coronavirus outbreak, pointing out the epidemic outside of China was only affecting a "tiny" proportion of the population. Ryan said that even at the epicentre of the crisis in the city of Wuhan in centra l Hubei Province, the "attack rate" - a measure of the speed of spread of the virus - was four per 100,000. "This is a very serious outbreak and it has the potential to grow, but we need to balance that in terms of the number of people infected . Outside Hubei this epidemic is affecting a very, very tiny , tiny proportion of people," be said. T edros also referred to an apparent decline in new cases of the disease in recent days but said that the trend "must be interpreted very cautiously". Sent from M ail for Windows 10 From: Carter Mecher NIH-001531 Date: Tues day, Feb ruary 18, 2020 10: 15 AM To: Canev a, Du ane; Tr acey McNamara ; Dr. Eva K Lee ; (b)( 6) Dodgen, D anie l (OSI ASPRJSPPR ) : DeBord , Kr istin (OS/AS PR /SPP R) ; Phill ips, Sa lly (OS/AS PR/ SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY(USA ); Lisa Koonin ; Warg o M ichael ; Walters , Wi lliam (STA TE .GOV) ; HAR VEY. MELISSA ; WO LF E. HERBERT ; Eastman, Alexander ; EV ANS , MARIEFRED ; Ca llahan, Michael V .,M.D .; ,__ ______ ..z-> ; (b)(6) ; Cb)( ; Johnson, ------Robe rt (O S/ASPR/ B ARDA) ; Yeskey, Kev in; D isbrow, Gary (OS/ASPR/BARDA ): Redd. John (OS/ASPR/ SPPR) : Hassell. Davi d (Chris) (OS/ASPR/1O): Hame l, Joseph (OS/ASPR/ 1O): Dean, Ch arity A@CDPH ; Rich ard Hatchett ; Lawler, James V; Kadlec , Rober t (OS / ASPR/1O); 'Martin, Gregory J CbH6)'; Borio, Luciana; Hanfling. Dan; McDonald, Eric: Wade . David; TARANTINO , DAVID A ; WILK INSON, THOMAS ; David Gru ber --------- (b)( 6); KAUSHIK,SANGEET A ; Nathan iel R upert Subject: RE: R ed D aw n Br eaking, COVID -19 Co llaborativ e, Fe b 16 sta1t NIH-001532 Update on cruise ship, Japan (implementing NPis) and South Korea (evacuating passengers) https://www .channelnewsas ia.com /news/asia/covid l 9-japan-virus testing -comple te-quarant inecru ise-ship- 12445788 88 more people test positive for COVID-19 on Diamond Princess cruise ship. The new cases take the total number of confirmed cases on the Diamond Princess to 542 - the biggest cluster outside the epicentre in China . [Almost 15% of the crew and passengers have been infected.] Japan has also confirmed at least 65 cases domesticalJy, including many involving people with no history of recent travel to China. Author ities have said the virus is being transmitted locally now, and have asked citizens to avoid crowds and non-essential gather ings. On Monday, the amateur portion of the Tokyo Marathon, which had been expected to attract some 38,000 runners, was cancelled. Only elite athletes wilJ now be able to take part. The public celebration for Emperor Naruh ito's birthday has NIH-001533 also been scrapped over virus fears. South Korea will send a presidential aircraft on Tuesday to fly back four nationals and one Japanese spouse, an official told reporters. There are 14 South Koreans on board in total, but the othe r ten have declined to be evacuated from the ship because they live in Japan, the Yon.hap news agency reported. V ietnam NPis https://protect2.fireeye .com/url?k= 5a2fa482-067bbdfe-5a2f95bd 0cc4 7adc5fa2a5b86bc 1581cf39c&u=https ://saig oneer. com/sai gon-health / ...ue-tocov id- 19 Due to COVID-19: As of February 15, all 63 provinces and cities in Vietnam have extended their schoo l closing time, 56 of which - including Saigon have announced that schoo ls will be closed until the end of Fe bruary. Ho Chi Minh City's People Committee proposing students stay at home until the end of March. Sent from Mai l for Windows 10 NIH-001534 From: Carte r Mecher Date: Tuesday, February 18, 2020 7:10AM To: Canev a, Duan e; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc·< \, _._ >; Dodgen, Daniel {OSIASPR/SPPR) ; DeBo rd, Kristin (OSI ASPR/SPPR) ; P hillips, Sally (OS/AS PR/SPPR) : David Marcozzi ; Hepburn, M atthew J CIV USARMY (USA) ; Lisa Koonin ; Wargo M ichael ; Walter s, Willi am (STATE.GOV) ; HARVEY, MELISS A; WOLFE , HERBER T; Eastm an, Alexande r; EV ANS, MARIEFRED ; Callahan , Michael V .,M.D .; .__ .i- _____ (b)(6) ; Johnson, ------Robert (OS/ASPR/BARDA) ; Yeskey , Kevin; Disbrow , Gary (OSI ASPR/BARDA) ; Redd, John (OS/ASPR/SPPR) : Ha ssell, Davi d {Chris) {OS/ASPR/1O); Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Richard Hatchett; Lawle r, James V; Kadlec, Rober t (OSI ASPR/1O): 'Martin, Gregory J CbH6) Borio, Luci an a; Hanfling , Dan; McDonald. Eric ; Wade, David ; TARAN TINO . DAVID A; WI LKINSON , THOM AS; David Gruber -------- (b)(6); KAUSHrK, SANGEE T A; Nathan iel R upert NIH-001535 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start More things to keep an eye on (attached links of stories and trans lations of news reports): Yesterday a 5th flight of evacuees from Hube i arrived in Japan. There were 65 on board and 7 peop le were symptomatic (11 %). Watch for the number of confirmed - it will provide a point est imate of prevalence of COVID19 in Hubei as of yeste rday. Sounds like this is the last flight japan will accept. Yesterday , Japan provided an update of all cases in Japan: • 53 people were infec ted in Japan and trave lers from China • 454 passengers and crew members on cruise ships, and • 13 people returned on NIH-001536 charter aircraft. • 520 people in total. • 23 people were determined to be seriously ill Watching for other countr ies to evacuate passengers from cruise ship • 256 Canadians on the Diamond Prince ss cruise ship • 32 tested + (as of Feb17) • A plane chartered by the Canadian gover nment has left for Japan to evacua te its nationals aboard a virus -hit cruise ship off Yokohama , TV Asahi reported on Tuesday, citing a NIH-001537 tweet by Canada's foreign minister Can't find anything about other countries evacuating passenge rs (UK, Hong Kong , Italy, etc.) La st thing . Am seeing stories from Japan re patients going from clinic to clinic with resp symptoms and fever and being confomed . They are finding nosocomial transmission- so underscores the concerns outlined in the proposal I outlined for realigning outpatient clinics . Sent from Mail for Windows 10 From: Ca rter Mecher Date: Monday, February 17, 2020 10:39 PM To: Canev a, Duane ; Tracey McNamara: Dr. Eva K Lee : (b)(6) (b)(6) Dodgen, --------Dan iel (OSI ASPR/SPPR) : DeBord, Kristin (OS/ASPR/SPPR): Phillips, Sally (OS/ASPR/SPPR): David Mar cozzi ; Hepbu rn, Matthew J CIV USARMY (USA); Lisa NIH-001538 Koonin ; Wargo Mic hael ; Walters . W illiam (ST ATE .GOV) ; HAR VEY , ME LISSA ; WOLF E, HERBERT ; Eastman, Alexander ; EV ANS . MARIEFRED ; Callahan, M ich ael V. ,M .D .; ; Johns on , -------Robe rt (OSIASPRJBARDA) ; Yeske y, Ke vin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OSIASPR/SPPR) ; Has sell. Davi d (Chris) (OSIASPR/10) : Hamel. Joseph (OSI ASPR/ 10 ): Dean , Charity A@CDPH ; Rich ard Hatchett ; Lawle r. James V; Kad lec. Rober t (OS / ASPR/IO) ; 'Martin, Gregory J Cb)(6); B orio, Luci an a; Hanfling. Dan ; McDo nald, Eric; Wade. David ; TARANTINO , DAVID A; WILKINSON, THOMA S; Davi d Gruber -------- (b)(6) KA USH lK, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking, COVI D- 19 Co llaborat ive , Feb 16 stait I really need help thinking tbru the testing piece (screening for COV ID-19). How do we protect the staff in outpatient clinics (where all the ILI is typically seen) and conserve PPE by shifting all the mi ld illness away from clinics and toward patien ts' homes using telephone careltelehealth and home healthcare and emp loying home NIH-001539 isolation for those who are infected and voluntary home quarantine for otherwise well (but exposed and potentially infected) household contacts? Having all the suspected patients coming in to clinics to be screened rea lly defeats the purpose. So how would very large numbers of outpatients get screened? Home screening? Drive thru screening? Or creating a free standing screening facility for rapid screening? Has anyone thought this thru (how you screen for disease plus promote adherence /compliance to home isolation and home quarantine and shift outpat ient care of patients with mild disease to telephone /home care to protect outpatient clinic staff? Looking for practica l solutions . Just to remind you , here are the estimates of demand (assuming we would need to screen all ILI)about 88K per day in primary care clinics across the US. I US Data US population 325,700 ,000 Hospital Beds 924,107 81,790 ICU Beds Hospital Admissions ER Visits Family Practice/PC Visits Total Deaths 36,353,946.00 145,600,000 481,963,000 2,813,503 A Day in the US Hospital Admissions NIH-001540 99,600 Inpatient Census (85% occupancy) ICU Census (85% occupancy) ER Visits Family Practice /PC Visits 785 ,491 69,522 398,904 1,320,447 7,708 Current Background of Illn ess Simila r to COVID-19 Deaths 2019-20 Flu Season MMWR Week 5 ILI Rate 6.7% 1.4M hospitalizations annually for pneumo nia Medicare Average LOS Pneumonia 6 days 55,672 pneumonia & influenz a death s annually Daily Hospital Admissions Pneumonia Hospital Census Pneumonia Da ily ILI cases seen in ERs Dai ly ILi cases seen in FP/PC clinics Dai ly pneumonia & influenza death s Sent from Mai l for Window s 10 From: Carte r Mecher Date: Monday, February 17, 2020 9:04 PM To: Canev a, Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Cc: C b > ; Dodgen, Dan ie I (OS/ ASPR/SPPR) : DeBord , Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally .___,_ _____ ..,r- NIH-001541 3,836 23,014 26,727 88,470 153 (OS/ASPR /SPPR) : David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA) : Lisa Koonin ; Wargo M ichael ; Walters, William (STATE .GOV) : HAR VEYL MELISSA; WOLF E, HERB ERT ; Eastman , Alexander ; EVANS, MARTEFRED; Callahan, Michael V .,M.D .; ______ ; John son, Rob ert (OS/ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OSI ASPR/BARDA) : Redd , John (OS/ASPR /SPPR) : Ha ssell, David (Chr is) (OS/AS PR/IO) : Hamel, Joseph (OS/AS PR/IO) : D ean, Charity A@C DPH ; Richard Hatchett ; Lawle r, James V; Kad lec, Rober t {OS/ASPR/10) ; 'Marti n, Gregorv J Cb)(6) ' ; Bo rio, Luci an a ; Hanfling. Dan ; McDonald, Er ic; Wade. David ; TARAN TINO , DA YID A; WI LKINSON, T HOM AS ; Davi d Grube r ,_ -------- (b)(6)• KAUSHIK, SANGE ETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start I tinkered with the strategy for integrating outpat ient clinics and hospital s for the care of COVID19 patient s. Proposing this for my system. NIH-001542 Sent from Mail for Windows 10 From: Car ter Mecher Date: Monday, February 17, 2020 7:17 PM To: Caneva , Duane ; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) (b)(6) Dodgen, --------Danie l (OS/ASPR/SPPR) ; DeBord, Kristin (OSI ASPR /SPPR) : Phill ips, Sa lly (OS/AS PR/SPPR) ; David Marco zzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wa rgo Michael ; Walters, W illiam (STAT E .GOV) ; HARVEY, MELISSA ; WOLFE, HERBER T ; Eastman, Alexander ; EV ANS, MARIEFRED ; Callahan . Michael V.,M.D .; (b)(6) Johnson. -------Robe rt (OS/ASPR/ BARDA) ; Yeskey, Kev in; Disbrow, Gary (OS/ASPR/BARDA) ; Redd , John (OS/AS PR/ SPPR) : Hassell, David (Chr is) (OS/ASPR/ 1O); Hamel, Joseph (OS/ASPR/ 1O); Dean, Charity A@CDP H ; Richard Hatchett; Lawler, James V; Kadlec, Robert (OS /ASPR/IO) : 'Martin, Gregory J Cb)( '; Borio, Luci an a; Hanfl ing. Dan ; McDonald, Er ic; Wade . David ; TARANTINO, DAVID A; WILKINSON,THOMAS ; David Gruber ---------- NIH-001543 (b)( KAUSHIK, SANGEETA ; Nathan iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start More details on evacuation of American passengers aboa rd the cru ise ship . Total evacuated: 177 + 151 = 328 bttps: //www .usatoday .com/story /tr ave l/cruises /2020 /02/ 17/coronavir us -diamond -princess -evacuees test-pos itive -allowe d-fly-unitedstate s/ 4 783787002 / Fourteen evacuees from the Diamond Princess cruise ship quarantined in Japan were allowed to fly back to the United States Sunday de spite testing positive for coronav irus, the U .S. State Departme nt and Health and Hwnan Services said in a jo int stateme nt. The evacuees were not symptomatic. "These individuals were mov ed in the most expeditious and safe manner to a specialized containment area on the evacuat ion aircraft to isolate them in accordance with standar d protoco ls," the statemen t, pub lished Sunday , read. NIH-001544 The State Department was unaware the individuals had coronavirus when they were being removed from the ship; they had tested negative just a few days before, Robert Kadlec, the assistant secre tary for preparedness and response at the U.S. Department of Health & Human Services, said on a phone call with repmiers. "If those results had come back four hours earlier before we'd started to disembark the ship and before these people were evacuees within an evacuation system, then it would've been a different discussion." Dr. William Walters, director of operational medicine at the U.S . Department of State, said on the call. Kadlec said that individuals received multiple screenings when moving from ship to bus to plane and a more extensive medical assessment upon arrival. Two charter flight s carry ing the Diamond Princ ess passenger s landed at military bases in Ca lifornia and Texas overn ight, starting the clock on a 14-day quarantine period to ensure those passengers don't have coronavirus . In tota l, approximately 380 Americans were on board the Diamond Princ ess ship for the duration of the cruise and quarant ine at sea. 'Something went awry': Why did US break Diamond Princess coronavirus quaran tine? NIH-001545 One plane carrying American passengers touched down at Travis Air Force Base in northern California just before 11:30 p.m. Sunday local time. A second flight arrived at Lackland Air Force Base in Texas around 2 ½ hours later, early Monday. The California flight had 177 people on it, seven of whom tested positive for coronavirns, Walters said. An additional three people were isolated during the flight for fever. Upon arrival, 171 stayed in Travis while six traveled to Omaha. It's unclear which passengers were transferred there and whether initial tests were positive or whether they were at risk for the vrrus. The Texas flight had 151 people board and included the other seven who tested positive for coronavirus. Two additional passengers were isolated on account of fever . All passengers who tested positive for coronavirus then moved on to Omaha. The aircraft design allowed passengers to sit in isolation thanks to a plastic divider at the tail of the aircraft. 13 high-risk passengers awa it test results at Nebraska Medical Center NIH-001546 Officials from the University of Nebra ska Medical Center and Nebraska Medicine confirmed that they are assessing 13 adults at their quarantine and bioconta inment facility in Omaha. "Late last night at about 2 or 3 a.m., we were asked to bring some individuals here who had either tested positive or had a high likelihood of testing positive because of symptoms they were exhibiting ," said Dr. Chris Kratochv il, the exec utive director at the Univers ity ofNebraska Medical Center ' s Global Center for Health Security. Twelve of them are housed in the quarant ine cente r while one man was transferred to the hospital's biocontainment unit for testing and observat ion because of symptoms including cough, fever, shortness of breath, lightheadedness and an undisclosed chron ic cond ition that wou ld make him particularly vulnerable to the COVID-19 VITUS. "He is doing good and in stable condition at this time ," reported Shelly Schwedhelm , Nebraska Medicine's executive director of emergency management and biopreparedness . She went on to note that "the folks in the quarantine center have all been tested, and we're waiting for those results ." She added that the other 12 are isolated in "very nice rooms with WiFi , TV and a sma ll refrigerator NIH-001547 - a lot of the amenities at hotels but with eng ineering contro ls" to prevent contaminated air from escapmg. Their test results , which are due back Monday afternoon, will determine whether the patients will be allowed to see their spouses or leave their rooms. Regardless of whether they test positive or negative, all of the new arrivals will spend at least 14 days in the facility , and any who test positive will likely stay longer, said Dr. Mike Wadman, the comedical director of the National Quarantine Unit. Kratochvil says it's possible that they may be asked to take more patients should more of the Diamond Princess passengers now in quarantine at the airbases test positive. Dr. Anthony Fauci , director of the Nationa l Institute of Allergy and Infectious Diseases at the Nat ional Institutes of Health, told the USA TOD AY editorial board and reporters Monday that the original idea to keep people safely quarantined on the ship wasn't unreasonable. But even with the quarantine process on the ship, virus transmissio n still occurred. "The quarantine process failed ," Fauci said. "I'd like to sugarcoat it and try to be diplomatic about it, but it failed. People were getting infected on that ship. Something went awry in the process of the quarantining on that ship. I don't NIH-001548 know what it was, but a lot of people got infected on that sh ip." USA TODAY reached out to Princess Cruises for clarification on how many Americans from the ship have the virus. Sent from Mai l for Windows 10 From: Caneva, Duane Date: Monday, February 17, 2020 4:51 PM To: Carter Meche r; Tracey McNamara ; Dr. Eva K Lee ; (b)(6) Dodgen, Daniel (OS/ASPR/SPPR): DeBo rd, Kris tin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin; Wargo Mic hael ; Walters, William (STATE.GOV): HARVEY, MELISSA ; WOLFE, HERBERT ; Eastman , Alexander ; EVANS , MARIEFRED ; Ca llahan , Mic hae l V .,M.D. ; (b)(6) ------,------ Johnson, Robert (OSI ASPR/BARDA); Yeskey , Kevi n; Disbrow , Gary (OSI ASPR/BARDA) : Red d, John (OS/ASPRJSPPR); Hassell, David (Chris) (OSI ASPR/ 1O); Hame l, NIH-001549 Joseph (OSI ASPR/ 1O); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J CbH6l'; Borio , ---------Luciana; Hanfling. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Gruber (b)( KAUSHIK, SANGEETA; Nath an iel Hupert Subject: Re: Red Daw n Breaki ng, COV ID- 19 Collaborative , Feb 16 start + Bob Glass Get Out look for iOS From: Carter Mecher (b)( Date: Monday, February 17, 2020 4:47:38 PM To: T racey McNamara Cb)C6J> ; Dr. EvaKLee Duane Dodgen, Dan iel (OS/ASPR/SPPR) Cb)C6) b ; DeBord, Kristin (OS/AS PR/ SPPR) NIH-001550 ________ (b) (6) ,. Phillips, Sally (OS/ASPR/SP PR) Cb)< > ; David Ma rcozzi -------- (b)(6) >; Hepburn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb)(6) Wargo --------Michael (b)(6) >; Walters, William (STATE.GOY ) >· (b)( ' HARVEY, MELISSA (b)( WOLFE , HERBERT (b)(6) Eas tman, Alexande r (b) (6) > ; EVANS, MARIEFRED (b)(6) >; Callahan , Mic hael V.,M.D. Johnson, Robert (OS/AS PR/BARDA) ________ (b)(6) > ; Ye skey, Kevin , >· (b)( Disbrow , Gary (OS/ASPR/BARDA) Redd, -------John (OS/ASPR/SP PR) Hassell, -------David (Chris) (OS/ASPR/10 ) Cb> (6) > ; Cb> (6) (b)(6) Hame l, Joseph (OS/ASPR/ 10) Cb)(6) ; Dean, Charity A@CDPH -------- (b)(6) NIH-001551 Richard Hatchett (b) (6} . ' Lawler, Jame s V (b) (6) ; ___________ Kadlec, Robert (OS/ASPR/10) (b) (6)1,• 'Martin, Grego ry J (b)(6) Lu ciana Hanfling , Dan ------(b)(6) > • McDonald,Eric ' (b)(6) ; Wade , David (b)(6) TARANTINO, DAVID A (b)(6) > • ' WILKINSON, THOMAS (b)(6) David Gruber (b)(6) -----------KAUSHIK , SANOEE TA >· ' (b)( Nathan iel Hupert >· ' (b) (6) Subject: RE: Red Dawn Breaking, COVID -19 Co llaborat ive, Feb 16 stait ('AL Tl o:-,,i:This email originated from outside of DHS. DO NOT click links or open attachmentsunJess you recognize and/or trust the sender. Contactyour component SOC with questions or concerns. A correction . Shou ld not have included breakdown of hospitalized since we have spotty data 9or could have used a range). Only solid data we have is numb er NIH-001552 confirmed (58), number in hospital (44), and number in ICU (.:::1). Mix of hospital pat ients is unknown (from the Singapore data the ratio of hospitalized to ICU has ranged from 6: 1 to 13: 1 from two data points). So estimates of severity looking only at the American passengers : ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) (44 cases actually hospitalized) ~2% of total cases requiring ICU admiss ion ( 1 case) Expected mortality for patients with pneumorua adm itted to ICU (15-50%) ; assuming 2% of those who become infected with COVID-19 require ICU care, these mortality rates equate to a CFR of 0.3%-1.0% Sent from Mai l for Windows 10 NIH-001553 From: Carte r Mecher Date: Monday , Februa ry 17, 2020 4:15 PM To: Tracey McNam ara ; Dr. Eva K Lee (b)(6) Caneva, -------Du ane; Dodg en , Danie l (OS/ASPR/ SPPR) ; De Bo rd, Kri stin (OSI AS PR/ SPPR) ; Phi llips, Sally ( OSI ASPR/ SPPR ): David Marcozz i; Hepburn, Matthew J CIV USARMY (USA) : L isa Koon in; Warg o M ichael ; Walters, W illiam (STATE .GOV) ; HARVEY. MEL ISSA ; WO LF E. HERBERT ; Eastm an, Alexande r ; EVANS, MARIEFRED; Call ahan , Michael V .,M.D.; (b)(6) John son, -------Rob e rt {OS/ASPR/BARDA) ; Yeskey . Kevin ; Disbrow . Gary (O S/ASPR/B ARDA) : Redd, John (O S/AS PR/ SPPR) ; Ha ssell, David {Chris) {OS/ASPR/ 1O): Ha mel, Joseph (OS/AS PR/1O) : D ean, Charity A@C DPH ; Ri chard Hat chett ; Lawler, Jame s V; Kad lec, Robert (OS / ASPR/1O) ; 'Mart in, Gregorv J Cb)< ; Borio, Lu ciana; Hanfling. Dan; McDonald , E ric; Wade, David ; TARAN TINO. DAV ID A; WI LKINS ON , TH OMAS ; David Grube r ------------ (b)(6) ; KA USHIK. SANGEE TA ; Na than iel R upert NIH-001554 Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 start Latest data from Singapore (77 cases; 4 children, 2 are asymptomatic) and Hong Kong (60 cases; no children) More puzzle pieces . Singapore status: h ttps://protect2 .fireeye .com/url?k= f6750fe4-aa21 1698-f6 753edb0cc4 7adc5 fa276d29cc40fd8c03f&u =https: //ww w.moh .gov .sg/newshighligh ...tion-confirmed Update on condition of confirmed cases To date, a total of 24 cases have fully recovered from the infection and have been discharged from hospital. Of the 53 confirmed cases who are still in hospital, most are stable or improving. Four are in critical condition in the inten sive care unit. [Ratio of hospitalized to ICU of 53/4 or ~ 13:1] Consistent with estimates in earlier emai l. [On Feb - 12 Singapore reported that 8 patients were in ICU.] NIH-001555 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 2:57PM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Daniel (OS/AS PR/SPPR) : DeBord, Kristin (OS/ ASPR/SPPR); P hillips, Sally (OS/ASPR/SPPR): David Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , William (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS . MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/ASPR/BARDA): Redd, John (OS/ASPR/SPPR): Hassell, David (Chris) (OS/ASPR/1O): Hame l, Jose ph (OS/ ASPR/ 1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb) Borio, --------Luci an a; Han fling, Da n; (6) McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A ; WILKINSON, THOMAS; David Gruber NIH-001556 (b)(6); KAUSHIK, SANGEETA ; Nathan iel Hupert ; (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborat ive, Feb 16 start Try ing to estimate severity by bringing a number of pieces together. The Diamond Princess Cruise Ship had a crew of l ,745 and 2,666 passengers (total pf3 ,7 11) Approximately 400 of the passengers are Americans (11 %) . Severa l days ago (Feb-13) we attempted to estimate disease severity using the current data being reported by the media (number of confirmed cases and ICU cases) as well as data on the outbreak in Singapore (number of confinned cases, number hospitalized , and number in ICU) (see attached Word file). Given the additional information becoming available (includ ing more specific information being reported by the media on the n umbers of Americans infected), I was interested in an updated crude estimate of severity (and to see how well the early predictions of severity matched with what was being reported by the media on illness in the Americans. See NIH-001557 latest re the cruise ship outbreak below (two stories). We can glean from these stories that the number infected is now up to 454. And 14 positive passengers were included among the Americans who were evacuated to the US. Canada, South Korea , Italy and Hong Kong announced Sunday that they would also an-ange charter flights to evacuate their citizens. A few additional pieces of data. News reports yesterday stated that 73 of the 355 confirmed cases from the cruise ship were asymptomatic (20%). Also , yesterday the media quoted Dr. Fauci that the total number of Americans who were confirmed to have COVID yesterday and who remained at hospitals in Japan at 44. Assuming that this number does not include the 14 confirmed cases that were evacuated, suggest s that the total number of Americans with confirmed COVID is 58. An ear lier news report from Feb-12 re a couple from California, noted the husband was in the ICU in Japan (so at least 1 American in the ICU). [" ...remained in a hospital intensive care unit and has been able to communica te with his family, his wife said in a phone interv iew from the ship, where she remained in quarantine. " https://protect2 .fireeye. com/ur l?k= 5b0 l 4cc3-075555bf -5b0 l 7dfc0cc4 7adc5fa25be62cfl a816fc6d& u=https: //web. archive.org/web/202002 12093725 /https://www .ocregister .com/2020/ 02/11/sout hern-california -man-oncru ise-sent-to-a-hosp ital-in-tokyo- NIH-001558 with -a-high-fever-tested-forcoronaviru s/ ] So, piecing all the data together: The ~400 Americans account for 11% of the 3,711 passengers and crew of the Diamond Princess. The 5 8 confirmed cases among Americans account for 12% of the 454 total confirmed COVID cases Assuming that proportion of asymptomatic cases in Americans is similar to the proportion of asymptomatic cases for the entire ship (73/355 or 20%), we would estimate the number of Americans with asymptomatic infection at ~12. Symptomatics would be 46. If 2% of cases result in ICU admission (based on earlier estimates on Feb -12 where 4 ICU cases were reported with 203 total confirmed cases), we would expect ~9 ICU cases overall with 454 infected. Media repo1ts from today note 19 of the passengers are "seriously ill, with some of whom treated in intensive care units." (Would be helpful to quantify "some" - from the earlier data, we would estimate about half that number would require ICU care at some point). For the 54 Americans confirmed to have COVID, we would estimate 1 would require ICU care if 2% of cases required ICU care (we are already aware of at least 1 American who was receiving ICU care in Japan). NIH-001559 So estimates of seve 1ity looking only at the American passengers: ~400 total American passengers 58 confirmed to have COVID-19 12 Asymptomatic (20%) 46 Symptomatic (80%) ~ 55% of total cases mildly ill (hospitalized for isolation only) (31 cases) ~25% of total cases acute ly ill requiring inpatient care ( 15 cases) ~2% of total cases requiring ICU admission ( 1 cases) Exp ecte d mort ality for patie nts with pneu mon la admi tted to ICU (1550% ); assu mm g NIH-001560 2% of thos e who beco me infec ted with co YID -19 requ ire ICU care, thes e mor talit y rates equa te to a CFR of 0.3 %- 1.0 % Those estimates fit pretty well with the estimates from Feb-13 . To firm up these numbers it would be useful to have actual numbers from Japan on ICU admissions, number requiring mechanical ventilation, number in the hospital because they are acutely ill, and number in the hospital because of isolation only (mildly ill or asymptomatic). Also would be helpful to have more granular NIH-001561 information on the Americans (hospita l data in Japan including number acutely ill, number needing ICU admission , and number only in the hospital for isolation). Wou ld also be critical to gather/compile the same infonnation from Canada, South Korea, Italy, Hong Kong , and other nations as they also evac uate their citizens. The cruise ship is a circumscribed population where it is possible to get a handle on severity fairly early in an epidemic . The limitation though, is the population on board that ship is elderly (so need to be careful about genera lizing to the entire population). But it is the best data we have. The reason why th is is so important is decisions re the implementation ofNPis depend upon severity (the more severe the more intense the NPis). The sooner we have a more accurate assessment of severity , the better for making plans for NPis. Sto1y # 1 https ://protect2 .fire eye .com/url?k= fb4e 1b73-a7 1a020f-fb4e2a4c0cc4 7adc5fa2 6b 70ca 76908c 81a4&u=https: //ww w3.nhk.or.jp/news/html/202002 17 NIH-001562 /kl 00 12289341000 .html?utm int= news contents new s-main 00 I Translation New virus cruise ship confirmed 99 new infections February 17, 2020 18:54 A new outbreak of the coronavirus was confirmed on February 17, with 99 new passengers and crew members infected on a cruise ship. As a result, 454 passengers and crew members of cruise ships have been infected, of which 19 are severely affected. According to the Ministry of Health, Labor and Welfare, a total of 99 new passengers, including 85 passengers and 14 crewmembers, were revealed on March 17 on the cruise ship "Diamond Princess" anchored in Yokohama Port. Among them, there are 43 Japanese. This means that a total of 1723 passengers and crew members were inspected on the cruise ship, and a total of 454 infection s were confirmed. According to the Ministry of Health , Labor and Welfare, 19 of the confim1ed individuals are seriously ill, some of whom are being treated in intensive care units. According to the Ministry of Health , Labor and Welfare, the Minist1y of Health , Labor and Welfare said that infections were confirmed one after another on NIH-001563 cruise ships. Need to be analyzed quickly." The Ministry of Health, Labor and Welfare has a policy to conduct a virus test on all passengers and crew members remain ing on board, and those who have a negative result will be asked to leave the ship after the 19th. Story #2 Fourteen peop le who were evacuated from the Diamond Princess cruise ship and flown back to the United States on charter flights tested positive fornovel coronavirus , according to a joint statement from the US Departments of State and Health and Human Services. The passengers are among the more than 300 people removed from the ship, which is docked off the Japanese port city of Yokohama , Sunday night and flown to milita1y bases in the Un ited States . US officials were notified that they had tested positive for coro naviru s during the evacuation process, after passengers had disembarked the ship, the agencies said in the joint statement Monday . The passenge rs had been tested two to three days before the NIH-001564 evacuation flights, the statement said. "After consultation with HHS officials, including experts from the HHS Office of the Assistant Secretary for Preparedness and Response, the State Department made the decision to allow the 14 individuals, who were in isolation, separated from other passengers, and continued to be asymptomat ic, to remain on the aircraft to complete the evacuation process," the agencies said. One charter flight carrying evacuated Americans arrived at Travis Air Force Base near Fairfield, Californ ia, around 11:28 p.m. loca l time Sunday. A second anived at Joint Base San AntonioLackland in San Antonio, Texas at 3:56 a.m . local time Monday. The passengers who tested positive were isolated from the other passengers during the flights, the statement said. And all passengers are being "closely monitored" throughout the flight. "Any who become symptomatic will be moved to the specialized conta inment area, where they will be treated," the statement said. After the flights land , any passengers that developed symptoms on the flights and those who had already tested positive will be transported to "an appropr iate location for continued isolation and care ." NIH-001565 The remaining passengers will remain under quarant ine for 14 days. Passengers arriving to Travis Air Force Base will be housed in the same facility as evacuees who arrived from Wuhan ear lier this month, a spokesperson for the base told CNN. New evacuees will be kept in a separate area of the Westwind Inn on the base, the spokesperson said. Before the announcement about the infected flight passengers, some Americans aboard the Diamond Princess said they didn't want to take a chance being evacuated for fear they would be subject to possible infect ion. Sacramento resident Matthew Smith told CNN affiliate KOVR that he would rather deal with issues in Japan than be evacuated and quarantined in the United States. "We decided we would j ust face whatever consequences here rather than exposing ourselves to that situation ," Smith told the affi liate ."It kind of didn't make any sense if the us was fearful that these were infected people which is why they're going to quarantine them for anot her 2 weeks to have thrown them all together" Smith's wife Katherine Codekas was met with some surprise when she told authoriti es that she and her husband weren't going to go with the other American evacuees, KOVR reported. NIH-001566 "They came back around again and I said no we're not going and they very sincerely wis hed us luck but there was a little look of surprise on their face ," Codekas explained to the affi liate. "You know, it's not like we're the last helicopter off the roof top in Ho Chi Mihn City ," she told KO VR . "We're on a boat and we're watching peop le go away and people just make different choices about how they want to confront the virus." Sent from Mai l for Windows 10 From: Carter Mecher Date: Monday , February 17, 2020 11:00 AM To: Tracey McNa mara ; Dr . Eva K Lee Cc: Canev a, Duane ; Dodgen, Daniel (OSIASPR/SPPR ); DeBord , Kristin (OS/AS PRJSPPR) : Phill ips, Sally (OS/AS PRJSPPR) ; David Marcozzi ; Hepb urn, Matthew J CIV USARMY (USA): Lisa Koonin ; Wargo Micha el; Walters, William (STA TE.GOV) : HARVEY, ME LISSA; WOLFE , HERBERT ; Eastm an, Alexander ; EV ANS. MA RIE FRED ; Ca llahan . Michae l V .,M.D .; ________ (b) (6) ,. NIH-001567 Cb)C ; Johnson, -------Robe rt (OS/ASPR/BARDA) ; Yeskey, Kevin ; D isbrow, Gmy (OS/ASP .R/BARDA) ; Redd, John (OS/ASPR/SPPR) ; Hassell, David (Chris) (OS/ASPR/10); Hame l, Joseph (OSI ASPR/10) : Dean , Charity A@CDPH ; Richard Hatchett ; Lawler, James V; Kad lec, Robert (OS / ASPR/ IO) ; 'Martin, Gregory J Cb)(6); Bor io, Luci ana; Han fling, Dan ; McDona ld, Eric; Wade , David ; T ARANTfNO, DAVID A; WILKINSON, THOMAS ; David Gruber -------- (b)(6); KAUSH CK, SANGEE TA ; Nathaniel Ru pert Subject: RE: Red Dawn Breaking, COVID-19 Collaborat ive, Feb 16 stait Attac hed is Bob Glass' origina l paper- his co-autho r was his high-schoo l age daugh ter. Here is a link to anothe r pape r. Glass RJ, Glass LM, Beye ler WE, Min HJ. Targeted social distancing designs for pandemic influenza. Emerg Infect Dis [serial on the In ternet]. 2006 Nov [date cited]. http: //dx.do i.org/ 10.3201/eidl 211. 060255 NIH-001568 Sent from Mail for Windows 10 From: Carter Mecl1er Date: Monday, February 17, 2020 9:59 AM To: T racey McNam ara ; Dr . Eva K Lee Cc: Canev a, Duan e; Do dgen, Dan iel (OS/AS PR/SPPR) : DeBord, Kristin (O S/ ASPR/SPPR); P hillips, Sally (OS/ASPR /SPPR) : Da vid Mar cozzi; Hepburn, Mat thew J CIV USARMY (USA ) : Lisa Koonin ; War go M ichael; Walters , W illiam (STATE .GOV) : HARVEY, MELISSA; WOLFE, HERBERT; Eastman, Alexander ; EVANS. MARIEFRED; Callahan, Michael V.,M .D .; (b)(6) Johnson, -------Robert {OS/ ASPR/BARDA) ; Yeskey, Kevi n; Disbrow, Gary (OS/AS PR/BARDA) : Red d, John (OS/AS PR/ SPPR) : Hassell, David (Chris) (OS/ASPR/1O): Hamel, Jose ph (OS/ ASPR/1O): Dean, Charity A@CDP H ; Rich ard Hatchett; Lawler, James V; Kadlec, Robert (OS/ASPR/1O): 'Marti n, Gregorv J Cb)(6) Borio, --------Luci ana; Hanfling, Dan; McDo nald, Er ic; Wade, Da vid ; TARAN TINO , DAVID A; WILKINSON, THOMAS; David Gruber NIH-001569 (b)(6); KAUS HI K, SANGEETA ; Nathan iel Hupert Subject: RE: R ed Dawn Breaking , COVI D-19 Collaborative , Feb 16 start This is the origi nal graph of Bob Gla ss' data. He modeled the various interventions alone or in combination. Along one axis are the social distancing measures from doin g nothing, to ju st closing schools but allowing kids to mix in the community , to social distancing of ki ds in th e community but keep ing school s open , to only social distancing of adults in the community , to closing school s and adults socia l distancing, to kid s and adult s socia l distancing in the community, to closing school s and socia l distancing of kid s in the community, to a combo of all 3. Along the other axis are other interventions including doing nothing, to quarantine (Q) , treatm ent of the ill wit h antivirals (T), proph ylaxis of con tacts (P), and variou s combinations. We observed what we called a " cliff effect" or phase tr ansition or a discontinuity once you closed scho ols and implemented social distanc ing among kids. The effect was non -line ar and drama tic. As a consequence we began a deep dive to better understand the sch ool env ironme nt (includi ng the NIH-001570 transportation system half the school age kids use each day) and school age kids. An unsung hero in all this was Lisa Koonin (who was at CDC at the time). If Richard birthed TLC, Lisa kept the baby alive in the neonata l ICU. We still have much to learn about this virus. Thus far, it seems to be sparing kids (just like SARS). We have been monitoring the reports from Ch ina as we ll as the detailed data we can see from Hong Kong , Singapore , and Japan - the numbers of kids remain very low and disease appears to be mild. Nonet heless, TLC (and the NPis) is focused on reducing disease transmission (effective ly decreasing Ro )- the interventions are rea lly agnostic to sever ity. It is why CDC had to scale the implementation of TLC (later called CMG) to severi ty. Despi te the abse nce of severe disease in kids , we really are still in the dark in tem1s of the amount of asympto matic disease or mild subclinical disease in kid s becau se we just haven ' t been able to look. I never forgot this gra ph of the data from Bob Glass and the inflection point that was observed when the combo of closing schools and social distancing of kids was imp lemented in his model. Although closing schools is complicated by its 2nd and 3 rd order impacts , it is actua lly a pretty clean intervent ion in tenns NIH-001571 of actually pulling the trigger (much cleaner than the other component s ofTLC) . If this outbreak proves to be as severe as our initial estimates, we should think long and hard before dismi ssing the early implementation of th is strategy (closing schools and social distancing of kids). Sent from Mai l for Windows 10 From: Cart er Mecher Date: Monday, February 17, 2020 8:57 AM To: Trac ey M cN amara ; Dr . Ev a K Lee Cc: Caneva, Duane ; Dodgen, Danie l (OS/ ASPR/SP PR) : DeBo rd, Kr istin (OS/ASPR /SPPR) ; Phill ips, Sally (OS/ASPR/ SPPR) ; David Ma rcozz i; Hepburn , Matthew J CIV USARMY (USA) : Lisa Koonin ; Warg o M ich ael ; W alters, Willi am (STA TE .GOV) : HARVEY , MELISSA ; WOL FE, HERB ER T ; Ea stman , Alexander ; EV ANS, MARIEFRED ; Ca llahan, M ichael V. ,M.D .; (b)(6) ; Johnson, --------Rob e rt (OS/ASPR/BARDA) ; Yeskey, Kev in; Disbrow , Gary (OS/ASPR/BARDA ): Redd, John (OS/ASPR /SPPR) ; Ha sse ll. Davi d (Chr is) (OS/ASPR/ 1O) : Hamel, NIH-001572 Joseph (OSI ASPR/ 10 ); Dean , Char ity A@CDP H ; Rich ard Hatchett ; La wle r, James V; Kadle c, Rober t (OSI ASPR/1O); 'Martin , Gregory J (b)(6) ' ; Borio , Lu ciana; H anflin g. Dan; McDonald, Eric; Wad e, David ; TARAN TINO, DA YID A ; WILKINS ON, THOMAS ; David Grube r '-------- ~ (b) (6); KAUSHIK, SANGEE TA ; Nath an iel Hupert Subject: RE: Red Dawn Breaking, COVID-19 Collaborative, Feb 16 start N Pi s are going to be central to our response to this outbreak (assuming our estimates of sever ity prove accurate). Th is email group has grovvn since we began (not quite epidemic-level growth, but getting there) . Lo oking ahead, I anticipate we might encoun ter pushback over the implemen tation ofN Pls and would exp ect s imi lar concerns/arguments as were raised back in 2006 when this strategy first emerged. It was one of the reasons I shared the updated data on US household s from American Community Survey, data on USDA programs for nutrit ional support (inc luding schoo l meal program s), data on schoo ls and enro llment, and even data on juvenile crime. The data that was gathered back in 2006 on socia l density in var ious environments NIH-001573 (homes , offices /workplaces, schools, daycare , etc., is unchanged) . For additional background and context, we attached are 3 papers on NPis and TLC for those who are interested. Richard Hatchett deserves full credit for birthing the idea of TLC (it was actually developed in response to the threat of HSN 1 and later adopted for pandemic influenza response). Duane, perhaps you can store these documents on MAX for safe keeping and access? The first paper is an historical review of the 1918 pandemic (the comparison of Philadelphia and St. Louis is emblematic of the lesson from 1918 that timing matters when deploying NPlsneed to be early) . The second paper is modeling work that was done to evaluate these strategies. At the time, modelers were focused on how best to contain an outbreak overseas (really focusing on using antivirals primarily for treatment and prophylaxis). They focused their models to evaluate the effectiveness of various strategies and quantities of antiviral medications required to quench an emerging outbreak . There were 3 groups who were doing this work back then. They each present their data in that paper . A few things to note. In all the model runs, they did not model perfection or 100% adherence (actually far from it). You will see scenarios from 30/60 (meaning 30% compliance and 60% ascertainment) on up to 90/80 ). (See figures 1) Even leaky implementation can reduce overall NIH-001574 attack rates. The modelers also looked at timing of implementation (see figure 3). At the time there was a great deal of skepticism-was hard for people to believe this was possible . Or even if TLC could be effective, was implementation practical given the challenges trying to implement and the 2nd and 3 rd order consequences (especially of closing schools). But the modeling data combined with the histolical data was the tipping point. Marty Cetron from CDC and Howard Markel from U of Michigan, published a more extensive historical review of the 1918 pandemic showing much the same. Since then, a group within CDC continued to work on this (collecting additional data from the 2009 pandemic and elsewhere). They published an update of CMG in MMWR in 2017. https://protect2 .fireeye .com/ur l?k= 3985fc87 -65d l e5fb-3985cdb8 0cc4 7adc5 fa2bb4a28 993 b5aa9e0& u=https://ww w .cdc.gov/media /dpk/cdc-247/preven ting-pandemic influenza /community -mitigation guidelines-for-preven tingpandem ic-flu.html The third paper, is a more recent paper (from 201 7) that Richard shared with me. The paper is a little dense, but I found this paper useful because it provides a vocabulary for strategies that we have raised (Symptom Monitoling vs NIH-001575 Quarantine of potentially infected but symptom-free contacts during an epidemic). This paper identifi es those conditions where SM or Q is preferred. Figure 1 is useful for und erstanding the challenges given the picture that seems to be emerging with this virus. This outbreak seems closer to pandemic flu than SARS in terms of transm ission dynamics (and hence the NPis we would need to employ). Lastly, another person, Bob Glass at Los Alamos, also did work on this separately from the MIDAS group. He actually began this work as pa1t of a science fair project for his daughter (using social contacts of his daughter and her classmat es at school to model disease transmission). He knew someone at VA who forwarded his work to us (chain of transmission). Early on (even before the MIDAS group modeled TLC), we had a "Eureka" moment when we graphed his data in Excel (I can share that single graph to anyone interested). Bob Glass was also interested in trying to determine when you could let up on the NPis during a pandemic. Here is a story about Bob Glas s and that work published in Fast Company https: //protect2.fueeye. com/ur l?k= 3862f880 -6436e l fc-3862c9 bf0cc4 7adc5fa29ce5afJ 1e3c2cd6 4&u=https ://ww w .fastcompany .corn/3058542 /thescientist s-who-simulate-the-endof -the-world I will see if I can find his work on when to reopen schools. Deci sions in terms of NIH-001576 letting up on NPis could be critical dow n the line. Sent from Mai l for Windows 10 From: Tra cey M cNa mar a Date: Sunday, February 16, 2020 7:10 PM To: Carter M ec her ; Dr. Eva K Lee Cc: Canev a, Duan e; Dodgen, Dan iel (OS/ASPR/SPPR ): DeBo rd, Kristin (OS/ASPR/SPPR) ; Phill ips, Sally (OS/ASPR/SPPR) ; David Marcozzi ; Hepburn , Mat thew J CIV USARMY (USA) : Lisa Koon in; Wargo M ichae l; Walters , W illiam (STA TE .GOV) : HARVEY , MELIS SA ; WOLFE, HERBERT ; Eastma n, Alexan der ; EV ANS, MARIEFRED ; Ca llaha n, M icha el V .,M.D. ; (b)(6) Johnson, -------Ro be rt (OS/ ASPR/BARDA) ; Yeskey, Kevin ; Disbrow, Gary (OS/AS PR/BARDA ); Red d, John (OS/ASPR /SPPR) ; Hassell , David (Clni s) (OSI ASPR/IO) : Hamel, Joseph (OS/ ASPR/1O) ; D ean, Charity A@CDPH ; Rich ard H atchett ; Lawle r, Ja mes V; Kad lec , Rober t (OS /ASPR/IO) ; 'Martin, Gregory J Cb)( ' ; B or io, Luci an a ; Ha nfling , Dan; M cDonal d, Er ic; Wade. Davi d ; --------- NIH-001577 T ARAN TINO, DAV ID A; WILKINSO N , THOMAS ; David Grube r (b)(6) KAUSHIK, SANGE ETA ; Nathan iel R upert Subject: Re: Red Dawn Breaking, COVID-19 Collaborative , Feb 16 start Here is the link to a town hall mtg at the Munich Security Conference. Shared by Dr Christian Haggenmiller , Dorector of the German Defense Institute. htt ps ://pro tect2.firee ye.com/url ?k=ec4e0592-b01a1cee ec4e34ad-0cc4 7 adc5fa2c00af41a186 719a2&u=https://s ecur ityconference .org/en/ medi al ibrary/asse t/town hal1-on-the coronavirus-o utbreak20200215 -1000/ Tracey Get Outlook for Android --- (b)(6) From: Dr. Eva K L ee > Date: Sunday, February 16, 2020 3:05:43 PM To: Carter Mecher (b)(6) > Cc: Caneva, Duane (b)(6) Dodgen, Dan iel (OS /ASPR/SPPR) NIH-001578 _________ , (b)(6) > • DeBord , Kristin (OS/ ASPR /SPPR) (b) (6) ; Phillips , Sally (OS/AS PR/S PPR ) Cb> (6) ; David Marcozzi (b)(6) -------- >; Hepbu rn, Matthew J CIV USARMY (USA) (b)(6) >; Lisa Koonin Cb> (6) Wargo -------Mich ael Walters, William (STATE .GOV ) (b)(6) HARVEY, MELISSA (b)(6) WOLFE, HERBERT (b)(6) E astman , Alexande r (b)(6)> ; EV ANS , MARIEFRED (b)(6) > ; Callahan , Michael V. ,M.D. Johnson, Robert (OS/ASPR/BARDA) (b)(6) Yeskey, Kevin (b)(6)> ; Disbrow , Gary (OSIAS PR/BARDA) --------John (OS /ASPR/SPP R) Cb> C6)Redd, Cb)(6)> ; Hassell, -------Da vid (Chris) (OS /ASPR/ 1O) (b)(6) Hame l, Joseph (OS/ASPR/1O) NIH-001579 (b) (6) ; Tracey McNamara (b)( Dean, Charity A@CDPH (b) (6); Richard Hatchett (b) (6); Lawler, James V (b) (6) ; Kadlec, Robert (OS/ ASPR/IO) (b)(6) 'Martin, Gregory J (b)(6) Lu ciana ------ Hanfling, Dan (b)(6)>; McDonald, Eric (b)(6) Wade, David (b)(6) TARANTINO, DAVIDA (b)(6) WILKINSON, THOMAS (b)(6) David Gruber KAUSHIK, SANGEETA (b)(6) Nathaniel Rupert (b)(6) Subject: RE: Red Dawn Break ing, COVID-19 Collaborative , Feb 16 sta 1t Hi Carter, great points. l. Separate current ED/ ICU patients from COVID-19 is a must. NIH-001580 2. Migrating current ED/ICU (non-COVID) patients to other care sites is great idea . 3. Caring for COVID-19 patients: leveraging ED/I CU personnel for high comp liance and usage of limited resources (PPE everything that goes with it) is very critical. Strategic usage and minimizing non-medical staff is necessary --- either these operators are well-trained and protected, or they cannot be there. 4. Concentrating care within ED/ICU for COVID-19 ensures rap id learning and sharing of knowledge among workers as they take care of these patients. Clearly from the standpoint of data collection and clinical symptoms record ing and organization, it is more feasible and allow for immediate analysis and feedback. 5. Strategic prioritization of limited resources is extremely impo1tant. We must do it now , because the supp ly chain is already being affected and it can go worse. 6. Primaiy care and call centers are good. If you want to do strategic testing , this is also a good place to involve . NIH-001581 7. So few children are reported among the confirmed positive case s . They may be good spreaders (not necessarily have to be super) and the more vulnerable people would be ones show up with symptomatic disease characteristics (or no/mild symptoms). Best, Eva (b)(6) mobi le (b)( Sent with ProtonMail Secure Email. ------- Original Message ------On Sunday, Febmary 16, 2020 4:30 PM, Carter Mecher (b) (6) > wrote: Wanted to bounce something off this group. I have been concerned about some of the preparedness efforts of healthcare systems NIH-001582 as they are ramping up their capab ilities to care for patients with COVID -19 presenting anywhere in their system. Staff working in ERs and ICUs are pretty familiar with the care of these types of patients and the use of appropriate PPE (standard contact and airborne precautions including eye protection). The staff at the hospitals undergo fit test ing for respirators, etc. Staff in outpatient clinics (especially remote comm unity based outpatient clinics) don't typically undergo fit testing for respirators. So ERs and ICUs have muscle memory for isolating patien ts and prov iding care to patients with infectious respiratory disease. Community based outpatient clinics do not. As part of the preparedness efforts, there has been interest in fit testing outpatient clinic staff and supp lying these clinics with PPE and establishing procedures for NIH-001583 evaluating COVID-19 patients in the commun ity based clinics. Given the projected shortages of PPE, that just doesn't seem like the most prudent approach. Rather than expand the care of potential COVID-19 patients to community based outpat ient clinics, I wou ld focus on hospital care--ERs and inpatient areas (especially ICUs). I would not pursue fit testing for staff working in outlying clinics. As a strategy, I suggested dividing COVID patients into two categories-(1 ) those with illness that is mild enough to be cared for at home ( self care or care by other family members); or (2) those who are sick enough to be seen in the ER for possible hosp italizat ion. I would refocus the efforts of outlying clinics away from COVID and toward keeping non-COVID patients with the usual mix of acute and chro nic illnesses we see from hypertension to CHF to diabetes, NIH-001584 etc., out of the ER and out of the hospital. That is what they can do to help unburden ERs and hospitals for the surge in COVID patients in ERs and hospitals. I would leverage telephone care as much as possible to handle patients with mild disease seeking care related to COVID (and quickly develop algorithms to detennine who has mild disease and can be managed by telephone at home and who needs to evaluated in the ER) . Think of it like the program Lisa developed for pandemic influenza (Nurse On Call) on steroids , minus the antivira l piece. Could we repurpose and leverage that program for COVID? Such a strategy would help to conse rve om PPE supply (avo id the expansion of fit testing and the redirection of already limited supplies of PPE to outlying clinics) and not ask outlying clinics to do something they don't typically do (that usually doesn't out turn out very well). If NIH-001585 the outlying clinics focused on what they normally do (caring for patients with chronic diseases), they could help the ER and hospitals cope with the demands of COVID. I would think about Urgent Care centers in the same way- to help to decompress ERs. I also think that we need to start thinking about strategies to conserve PPE for hospitals. I'm concerned about the projected burn rates and the supply chains for PPE. Click on Amazon and check out the prices now. Or click on WalMart (can't pick up any masks from Wa lMart now). I saw one supplier selling 200 surgica l masks on WalMaii's site for only $459.99. Such a deal. As a conservation strategy , we might think about limiting the amount of staff interacting with infected patients and cohorting patients (even thinking of strateg ies to minimize need for NIH-001586 housekeeping or food service or lab services from enter ing areas with COVID patients-think Ebola-like strateg ies (not out of concern of disease transmission but simply to limit number of staff to conserve PPE). Could do something similar with ERs (akin to what pediatricians do to separate sick call patients from other appointments). I have recommend prioritizing PPE for EDs and ICUs as well as specific inpatient areas where we would likely initially cohort patients , not pursuing fit testing of outpatient clinic staff, and shifting patients with mild COVID disease to telephone care and away from outpatient clinics. I know several of you are part of large healthcare systems. Am curious how others are approaching this challenge. I am also resending the questions I posed NIH-001587 for handling sick ER/ho spital staff or staff members with a confinned case of COVID in their hou seho ld. Ca11er Sent from Mai l for Windows 10 From: Caneva, Duane Date: Sunday, February 16, 2020 3:24 PM To: Dodgen , Daniel (OSI ASPR/SPPR) ; DeBord, Krist in ( OSIASPR/SPPR); Phi llips, Sally (OS /ASPR/SPPR) ; Dav id Marcozz i; Hepburn, Matthew J CIV USARMY (USA); Lisa Koonin ; Wargo Michae l; Walters, William (STAT E.GOV) ; HARVEY, MELISSA ; WOLFE, HERBERT; Eastman, Alexander; EVANS, MARIEFRED; Ca llahan, M ichae l V.,M.D. ; )(6) ; Johnson. Robert NIH-001588 (OSIAS PR/BARDA) : Yeskey, Kev in; Disbrow, Gary (OSI ASPR/BARDA) : Redd, John (OS IASP R/SPP R) : Hasse ll, David (Clu-is) (OS /ASPR/10 ): Ham el, Joseph (OSIASPR/JO) : Tra cey McNamara ; Dean , Charity A@CDPH ; Ric hard Hatch ett ; Lawler, Jame s V ; Kadlec, Robert (OSI ASPR/10) ; 'Ma11in, Greg ory J (b)(6) :t; Borio , Luciana ; Hanfling, Dan ; McDonald, Er ic; Wad e, David ; TARAN TINO, DAVIDA ; WlLKINSON, THOMAS ; Dav id Gruber KA USHIK, SANGEET A; Dr . Eva K Lee ; Nathan iel Hupert ; Carter Mecher Subject: Re: Red Dawn Breaking, COVID-19 Co llaborative , Feb 16 start Sorry for spam. + Carrer NIH-001589 Get Outloo k for iOS From: Caneva , Duane Date: Sunday, February 16, 2020 10:21:38 AM To: Dodgen , Danie l (OS /ASPR/SPP R) (b)(6) >; DeBord, Kristin ( OSIASPR/S PPR) (b)(6) >; Phillips , Sally (OS/ ASPR/S PPR) (b)(6) D avid Marcozzi (b)(6) Hepb urn, Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koon in (b)(6) Walt ers, William (STAT E.GOVJ (b)(6) >; H ARVEY , MELISSA (b)(6) WOLFE , HE RBERT )(6) ; Eastman, A lexander )(6) NIH-001590 EVANS, MARIEFRED (b)(6) Callahan, Michael V.,M.D. l> ;Johnson, Robert (OS / ASPR/BARDA) )(6) > ; Yeskey, Kevin )(6) Disbrow, Gary S/ ASPR/BARDA) )(6) >; Redd, John (OS / ASPR/S PPR) (b)(6) >; Hassell, David (Chris) (OS /ASPR/ 1O) )(6) Hame l, Joseph (OS /ASPR/1O) (b)(6) > ; Tracey McNamara )(6) Dean, Char ity A@CDPH )(6) ; Richard H tc ett )(6) Lawler , James V )(6) ; Kadlec, Robert NIH-001591 (OS/ASPR/IO) )(6) ; 'M artin, Gregory J (b)(6) >; Borio, Luciana (b)( Hanfling , Dan (b)( ; McDonald , Eric (b)(6) Wad e, Dav id )(6) TARANTINO, DAVID A )(6) Barie , Ralph S (b)(6) ■ WILKINSON, THOMAS >; Hassell, David (Chris) (OS/ASPR/10) (b)(6) > ; David Grub er (b)( KA USHIK , SANGEETA (b)(6) KLee Nathaniel Rupert )(6) > Subject: RE: Red Dawn Breaking, COVID-19 NIH-001592 Collaborative , Feb 16 start Some Mark Lipsitcb Tweets copied. Sorry, might not be in the right order ... "So far, we have conducted tests for 1,219 individuals. Of those , 355 people tested positive. Of those, 73 individuals are not showing symptom s," Japan ' s health minister says Marc Lipsitch (@mlipsitch) 14/02/2020, 17:42 I did actually say the quote that is going around , but the article contained vital context -- we don't know what propor tion are symptomatic. Also we have only a rough estimate of what proportion of symptomat ic people will have severe outcomes . pie .twitte r.comic W zvINSZ Bm Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:43 Why do I think a pandem ic is likely? The infect ion is in many parts of China and many count r ies in the world , with meaning ful numbers of secondary transmissions . The scale is much larger than SARS for examp le (where the US had many introduct ions and no known onward transmissio n) NIH-001593 Marc Lipsitch (@mlipsitc h) 14/02/2020, 17:45 Why do I think 40-70% infected? Simpl e math models with oversimp le assumpt ions would pred ict far more than that given the ROestimates in the 2-3 range (80-90%) . Making more realistic assumptions about mixing, perhaps a little help from seasonality, brings the numb ers down Marc Lipsitch (@mlipsitch ) 14/02/2020 , 17 :48 pandemic flu in 1968 was estimated to _symptomatically_ infect 40% of the population, and in 1918 30%. Tho se likely had RO less than COVID- 19. Belo w is from stacks .cdc.gov /view/cdc/ 11425 pic.tw itter .com/EMwjE pA49s Marc Lipsitch (@mlipsitch ) 14/02/2020, 17:49 What cou ld make this scenario not happen ? 1) cond itions in ·wuhan could be so different in some fundamental way from elsewh ere that we are mistaken in expecting further outbreaks to have basic aspects in common. No reason I know of to think that but a forma l possibility NIH-001594 Marc Lipsitch (@ mlipsitch) 14/02/2020, 17:53 2) There could be a higher degree of superspreading than has been appreciated ("dispers ion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission. hopkinsidd.github.io/nCo VSandbox/D ... . Ma rc Lipsitch (@mlipsitch) 14/02/2020, 17 :53 2) There could be a higher deg ree of superspreading than has been appreciated ("dispersion in RO") which could mean that many locations outside Wuhan could "get lucky" and escape major onward transmission . hopkinsidd. github .io/nCo V-Sandbox/D ... . Marc Lip sitch (@mlipsitch) 14/02/2020 , 17:55 3) Control measures could be extremely effective in locations that have had time to prepare. Maybe in a few, but seems unlikely that is the case in all, especially countries with stretched health systems. Marc Lip sitch (@mlipsitch ) NIH-001595 14/02/2020, 17:56 4) Seasonalfactors could be much more powerful at reducingtransmissionthan we currently expect. That doesn't help the Southern hemisphere , and is not consisten t wi th behavior in Ch ina (preprint in queue from D @Ma uSantil lana D et al.) From: Caneva, Duane Date: Sunday, February 16, 2020 9:39 AM To: Dodgen , Daniel (OS /ASPR/S P PR) (b)(6) >; DeBord, Kristin (OS / ASPR/SPPR) (b)(6) >; Phillips , Sally (OS / ASPR/S PPR) (b)(6) Hepburn , Matthew J CIVUSARMY (USA) (b)(6) ; Lisa Koonin (b)(6) Walters, William (b)(6) H ARVEY , M ELISSA NIH-001596 )(6) >; WOLFE, HERBERT (b) (6)_ 111111> ;Eastman, Alexa nder (b)(6) EVANS, MARIEFRED __.. ; (b)(6) Callahan, Michael V.,M.D. ; Johnson, Robert (OS / ASPR/BARDA) (b)(6) 1111111> ;Yeskey, Kevin (b)( Disbrow , Gary (OS /ASPR/BARDA) (b)(6) 1111Redd, John (OS / ASPR/SPPR) (b)(6) >; Hassell, David (Chris) .>; (0S /ASPR/IO) (b)(6) Hamel, Joseph (0S /ASPR/IO) (b)(6) Ill> ; Tracey McNamara (b)(6) > ; Dean , Char ity A@CDPH (b)(6) Caneva, Duane NIH-001597 )(6) ; Richard Hatchett )(6) ; Lawler, James V (b)(6) >; Kadlec, Robert (OS/ASPR/10) )(6) >; 'Martin, Gregory J (b) (6), >; Borio, Luci ana (b)( Hanfling, Dan (b)(6)> ; McDonald , Eric )(6) _ Wade, David )(6) TARANTINO, DAVID A (b)(6) >; Barie, Ralph S )(6) WILKINSON, THOMAS (b)(6) >; Hassell, Dav id (Chris) (OS/ASPR/10) (b)(6) Da vid Gruber (b)( KA US HIK, SANGEETA (b)(6) NIH-001598 Subject: Red Dawn Breaking , COVID-19 Co llaborat ive, Feb 16 start Purpose: This is a new Red Dawn String to cut down the size from the previous string, opportunity to provide thoughts, concerns, raise issues, share information across various co lleagues responding to COVID-19. Including all from previous string plus a few additional folks. Duane C. Caneva, MD, MS Chief Medical Officer Department of Homeland Security (b)(6) Executive Assistant: (b)(6) NIH-001599 (b)(6) (U) Warning : This document is UNCLASS IFIED!/FOR OFFICIAL USE ONLY (U//FO UO). It contains informatio n that may be exempt from public release under the Freedom of Infor m ation Act NIH-001600 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 24 Feb 2020 11:08:54 +0000 Gilman, James (NIH/CC/OD) [El;Tabak, Lawrence (NIH/OD) [El Davey, Richard (NIH/NIAID) [El RE: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB Date: To: Cc: Subject: We should probably also inc lude Rick Davey on all commun ication regarding such patients From: Gilman, James {NIH/CC/OD) [E] _______ Cb) _C6>r _> Date: Monday, February 24, 2020 12:40 AM -------~~ To: Tabak, Lawrence (NIH/OD) [E] (b)(6J; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: 3 COVID-19Asymptomatic Positive Individuals Identified at Travis AFB --------- Larry Best POCis Dr Palmore. Jim --------- (b)(6)> From: "Tabak, Lawrence (NIH/OD) [E]" Date: Sunday, February 23, 2020 at 10:02:41 PM To: "Fauci, Anthony {NIH/N IAID) [E]" -------=(b""" )(=6l, "Gilman, James (NIH/CC/OD) [E]" (b)( > Subject: FW: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB Who is P-O-C, related to transfer? Pius From: "Kadlec, Robert (OS/ASPR/ 1O) " Date: Sunday, Februa ry 23, 2020 at 9:56 PM --------- (b)(6J> -------~= To: "Ha rrison, Brian (HHS/ 1OS)" CbH6J>,"Mango, Paul (HHS/ 1O5)" (b)( >, "Stecker, Judy (OS/ 10S)" CbH6J>,"Mu rphy, Ryan (b)( >, (OS/ASPA)" < CbH6J>,"Arbes, Sarah (HHS/ASL)" Anthony Fauci CbH6J>, "Tabak , Lawrence (NIH/OD) [E]" __ ___:, __ -====.;~:::-::----:-::::--:-- "".":::======~~ 6)" Red fie Id, Robert R. (CDC/OD)" -----------------Robe rt (Kyle) (CDC/OD/OCS)" CbH6J> (b)( CbH6J 1, "McGowan, Cc: "Lee, Scott (OS/ASPR/EMMO)" CbH6J>,"Yeskey, Kevin (OS/ASPR/1O)" CbH6J,"Waters, Cicely (OS/ASPR/OEA)" CbH6J,"Shuy, Bryan {OS/ASPR/10)" CbH6J,"Greene, Jonathan (OS/ASPR/EMMO)" _, ,>, " Imbriale, Samue l {OS/ASPR/SIIM)" CbH6J CbH6J, "Austin, Meredith (uscg.mil)" (b)(6) "Herrmann, Jack (OS/ASPR/OEA)" (b)(6j _________ Subje ct: 3 COVID-19 Asymptomatic Positive Individuals Identified at Travis AFB NIH-001601 Initial CDC testing of the 100 individuals repatriated from the Diamond Princess yielded three individuals COVID-19 POSwho are currently asymptomatic at Travis. These individuals are being transferred to local hospital for evaluation and admission. Currentl Y.,ASPRTEAM at Travis is asce_rt""a_in_i_n~g ,_____ ..,._.,.,,., (b)(5) My team is working the details of transfer via aeromedical aircraft. Dr Kevin Yeskey and CAPTScott Lee copied here are leading the operational planning nr_3_c_ o1u:.se.c;_ of_actio.,..,._ · _____________________________ ..,.,.""' (b) (5) Will advise as these course are pursued in parallel. WILL NEED A POC at NIH to connect with Dr Yeskey and CAPT Lee ASAP to begin arrangements . NIH-001602 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 14:01:20 +0000 Grigsby, Garrett (HHS/0S/OGA) RE: CDC L2 THN Korea To: Subject: Thanks, Garrett. From: Grigsby, Garrett (HHS/OS/OGA) Se nt : Saturday, February 22, 2020 8:56 AM (b)(6) --------- To: Fauci, Anthony (NIH/NIAID) [ E] --------=- (b)'""'(= 6)> Subject: Re: CDC L2 THN Korea Dr F, Here it is: --------- (b)(6) Sent from my iPhone _______ _, (b)(6) On Feb 21, 2020, at 9:41 PM, Fauci, Anthony (NIH/NIAID) [E) wrote: Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/0S/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Zebley, Kyle {HHS/OS/OGA) (b)(6)>; Harrison, Brian {HHS/10S) >; Shuy, Bryan {OS/ASPR/10) < --------Subje ct : Fwd: CDCL2 THN Korea (b)( Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks!! Sent from my iPhone NIH-001656 (b)(6) Begin forwarded message: (b)(6) From: "Cetro n, Marty (CDC/DDID/NCEZID/DGMQ)" Date: February 21, 2020 at 9:01 :06 PM EST To: (b)(6) {OS/10S)' (b)(6)>, " Harrison, Brian (HHS/IOS)" (b)(6) "Grigsby , Garrett (HHS/05/0GA) " ------- ========' (b ~)=:(6) ~> CbH6),"Cetron , Marty (CDC/DDID/NCEZID/DGMQ)" ·-..:.....:::== (b ==:: )::c: (6) :c;>- ... Cc: "Redfield, Robert R. (CDC/OD)" Subject: CDCL2THN Korea Per WHTF request CDC l2 THN RoK. Please share w Sec Biegun at DOS.We w ill post whe n he is ready presumably Sat Thks MSC NIH-001657 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sat, 22 Feb 2020 02:40:45 +0000 Grigsby, Garrett (HHS/OS/OGA) FW: CDC L2 THN Korea Coronavirus L2 - South Korea.docx, ATT0O0Ol.htm Garrett: Please send me the call in number for tomorrow's call at 11:00 AM Thanks, Tony From: Grigsby, Garrett (HHS/OS/OGA) (b)(6) Date: Friday, February 21, 2020 9:24 PM To: Phil Ferro (b)(6)>; Fauci, Anthony (NIH/NIAID) [E]_______ Cc: Zebley, Kyle {HHS/OS/OGA) --------- Cb _H_6) CbH6>!>; Harrison, Brian (HHS/IOS) (b)( > (b)(6) Shuy, Bryan (OS/ASPR/IO) Subject: Fwd: CDC L2 THN Korea Gentlemen, Can you please circulate this for discussion at the 11am call tomorrow? Many thanks !! Sent from my iPhone Begin forwarded message: From: "Cetron, Marty (CDC/DDID/NCEZID/DGMQ )" (b)(6)> Date: February 21, 2020 at 9:01:06 PM EST To: (b)(6) (O5/IOS)" (b)(6)>, "Ha rrison, Brian (HHS/1O5)" (b)(6), , "Grigsby, Garrett (HHS/OS/OGA) Cc: "Redf ield, Robert R. (CDC/OD)" (b)(6), "Cetron, Marty _________ (CDC/DDID/NCEZID/DGMQ)" Subject: CDCL2 THN Korea ---------.., ~ --------- (b)(6)> (b)(6) Per WHTF request CDC L2 THN RoK. Please share w Sec Biegun at DOS. We will post when he is ready presumably Sat Thks MSC NIH-001680 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Fri, 21 Feb 2020 10:55:47 +0000 Kadlec, Robert (OS/ASPR/10 ) RE:Good morning Bob: No problem . Got you covered . Best, Tony From: Kadlec, Robert (OS/ASPR/10) Se nt: Friday, Februa ry 21, 2020 5:53 AM To: Fauci, Anthony (NIH/N IAID) [E] Subj ect : Good morn ing Im port ance: High --------- ------~~ -------- (b)(6)> Cb)( > Tony during today's t able top as we walk through the placement I will ask you to walk through t he Critica l Info r mation Requirements and ask you to highlight what we know, don't know and what we th ink about the this coronavi rus. l et me know if you have any questions . Best Bob NIH-001697 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 20 Feb 2020 21:26:05 +0000 To: Eisinger, Robert (NIH/NIAID) [El Subject: FW: HHS COVID 19 Response TIX Concept Placemat_Senior Leader _19Feb2020 v2 .pptx Attachments : HHS COVID 19 Response TTX Concept Placemat_Senior Leader _19Feb20 20v2 .pptx , ATTOOOOl.htm Here it is Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . -------- From: Kadlec, Robert (OS/ASPR/10) < (b)( > Date: Wed nesday, February 19, 2020 6:15 PM To: Fauci, Anthony (NIH/NIAID) (El (b)(6) Subject: Fwd: HHS COVID 19 Response TTX Concept Placemat _Senior Leader _1 9Feb2020v2 .pptx -------::--:--;= Sent from my iPhone Begin forwarded message: From: "Mackay, Thomas (OS/ASPR/EEAA)" ---------=c-= (b)(6)> Date: February 19, 2020 at 5:55:17 PM EST To: "Kadlec, Robert (OS/ASPR/10)" (b)(6), "Yeskey, Kevin (OS/ASPR/10)" (b)(6)> Cc: "Ford-Barnes, Arwent hia (OS/ASPR/10)" CbH6J>, "Hol land, Tara (OS/ASPR/EMMO)" (b)((;)>, "Callahan, Victoria (OS/ASPR/10) (CTR)" (b)(6)> Subject: HHS COVID 19 Response TIX Concept Placemat_Senior leader_19Feb2020v2 .pptx NIH-001712 Gentlemen - attached is the latest version of the Placemat . The reason there are four slides is to give you the option of how the backside is laid out . Slide one and three are identical, the information on slides two and four are also identical just laid out differently . Standing by for corrections as necessary. v/rTom NIH-001713 Fauci, Anthony (NIH/NIAID) [E) Thu, 20 Feb 2020 04:02:40 +0000 To: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID);Giroir, Brett (HHS/OASH);Shuy, Bryan (OS/ASPR/IO);Schuchat, Anne MD (CDC/0D);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);McGowan, Robert (Kyle) (CDC/0D/OCS);Grigsby, Garrett (HHS/0S/OGA);Zebley, Kyle (HHS/0S/OGA);Redfield, Robert R. (CDC/OD) Subject: RE: Updated Draft in Track Changes Attachme nts: Phases of USG nCoV Response _WHTF_13 Feb_PCC_Master.Final ASPREdits CDC BG.docx From: Date: HHS Tea m : I have been following these various iterations closely over the past couple of hours and I agree with Dan. It looks like we have actua lly finally arrived at a good place and a point of comfortable agreement latest tracked document between ASPR and CDC. Am I correct and do we all agree with the (see attached)? Thanks, Tony From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Se nt: Wednesday, February 19, 2020 10:54 PM To: Giroir, Brett {HHS/OASH) ------- CbH6J>; Shuy, Bryan (OS/ASPR/I0) >; Schuchat, Anne MD (CDC/OD) (b)(6)>; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Fauci, Anthony (N IH/NIAID) [E) (b)( >; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6)>; Grigsby, Garrett (HHS/0S/OGA) (b)(6)>; Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Redfield, Robert R. 7( C ::-D-:C-:/0:-D ---:)===::,:: (b:)(~ ;:: > (b)( -----~~ Subject: RE: Updated Draft in Track Changes Here with Adm Giroir's input as well. I think we may have arrived? Dan. From: Giroir, Brett (HHS/OASH) (b)(6) Date: Wednesday, February 19, 2020 10 :06 PM To: Shuy, Bryan (OS/ASPR/10) CbH6)>; Schuchat, Anne MD (CDC/OD) (b)(6); Cetron, Marty {CDC/DDID/NCEZID/DGMQ) ; Jernigan, Daniel B. {CDC/DDID/NCIRD/ID) CbH6)>;Fauci, Anthony (NIH/NIAID) [E) CbH6)>;McGowan , Robert (Kyle) (CDC/0D/OCS) CbH6)>; Grigsby, Garrett (HHS/0S/OGA) CbH6J>; Zebley, Kyle (HHS/0S/OGA) (b)(6) Subject: RE: Updated Draft in Track Changes (b) (5) Please include me on the emai l exchange . NIH-001726 I am happy to point force the issue, which I can and will, but I assume it was an accidental om mission BG Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) From: Giroir, Brett (HHS/OASH) Date: Wed nesday, February 19, 2020 10 :02 PM To: Shuy, Bryan (OS/ASPR/I0) (b)(6)>; Schuchat , Anne MD (CDC/OD) (b)(6)>; Cetron , Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/10) Cb> _<_6)>; Antho ny (NIH/NIAID) Fauci [E] (b)(6)> ; McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6); Grigsby, Garrett (HHS/0S/OGA) (b)(6)> ; Zebley, Kyle (HHS/OS/OGA) (b)(6)> Subject: RE: Updat ed Draft in Track Changes Importance: High ____ --------- · (b) (5) Brett P. Giroir, MD ADM, US Public Health Service Assistant Secretary for Health (ASH) 200 Independence Avenue, SW Washington, DC 20201 Office Phone: (b) (6) Begin forwarded message: NIH-001727 From: "Kadlec , Robert (OS/ASPR/IO)" (b)(6) Date: February 19, 2020 at 9:03 :33 PM EST ---~~ CbH6J>, "Cetron, Marty To: "Schuchat, Anne MD (CDC /OD)" (CDC/DDID/NCEZID/DGMQ)" CbH6) p, , "Jernigan, Daniel B. (CDC/DDID/NCIRD/ID)" CbH 6}, "Fauci, Anthony (NIH/NWD) (b)( ----- [E]" Cc: "McGowan , Robert (Kyle) (CDC/OD/OCS)" Cb><6J , "Shuy , B1yan (OS/ASPR /1O)" CbH6J >, "Grig sby , Garrett (HHS/OS/OGA)" Cb><, "Zebley , Kyle (HHS/OS /OGA)" (b)(6)> Subject: Updated Draft in Track Changes Please accept my apologies for the delay I had a competing priority action but please find attached . NIH-001728 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Wed, 19 Feb 2020 01:38:52 +0000 Billet, Courtney (NIH/NIAID) [E] RE: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan (b)(6)> From: Billet, Courtney (NIH/NIAID) [E] Date: Tuesday, February 18, 2020 8:23 PM -------=-:-:= (b:-:)(=6)~> To: Fauci, Anthony (NIH/NIAID) [~ E]:.======= Cc: Folkers, Greg (NIH/NIAID) [El (b)(6) (b)(6); Conrad , Patricia (NIH/NIAID) [E] --------- Subj ect : Fwd: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: "Hall, Bill (HHS/ASPA)" (b)(6)> Dat e: Tuesday, February 18, 2020 at 4:52:06 PM Subj ect : FW: CDC Media Statement: Update on the Diamond Princess Cruise Ship in Japan From: MMWR Media List On Beha lf Of Media@cdc .gov (CDC) Se nt : Tuesday, February 18, 2020 4:46 PM To: MMWR-MEDIA@LISTSERV.CDC.GOV Subje ct : CDC Media Statement : Update on the Diamond Princess Cruise Ship in Japan Media Statement For Immediate Release Tuesday, February 18, 2020 Contact: CDC Media Relation s (404) 639-3286 NIH-001766 Update on the Diamond Princess Cruise Ship in Japan We commend the extraordinary efforts by the Government of Japan to institute quarantine measures onboard the Diamond Princess. While the quarantine potentially conferred a significant public health benefit in slowing transmission, CDC's assessment is that it may not have been sufficient to prevent transmission among individuals on the ship. CDC believes the rate of new infections on board, especially among those witho ut symptoms , represents an ongoing risk. Therefore, to protect the health of the American public, all passengers and crew of the ship have been placed under travel restrictions, preventing them from returning to the United States for at least 14 days after they had left the Diamond Princess. Currently , there are more than 100 U.S. citizens still onboard the Diamond Princess cruise ship or in hospitals in Japan. These citizens have been placed under the restrictions, as have the ship's other passenge rs and crew . After disembarkation from the Diamond Princess, these passengers and crew will be required to wait 14 days without having symptoms or a positive coronavirus test result before they are permitted to board flights to the United States. If an individual from this cruise arrives in the United States before the 14-day period ends, they will still be subject to a mandatory quarantine until they have completed the 14-day period with no symptoms or positive coronavirus test results. Because of their high-risk exposure, there may be additional confirmed cases of COVID-19 among the remaining passengers on board the Diamond Princess. CDC is committed to protecting the health and safety of all Americans. We continue to believe that the risk of exposure to COVID-19 to the general public in the United States is currently low. The U.S. Government is taking these measures to protect the Diamond Princess passengers and crew, their loved ones, the traveling public, and communities within the Un ited States. ### U.S . Department of Hea lth and Human Services CDC works 2417 protecting America's health, safety and security. Whether diseases start at home or abroad, are curable or preventable , chronic or acute, or from human activity or deliberate attack, CDC responds to America's most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world. If you would like to unsubscribe from this ListServ LIST , please send an email to LIST@cdc.gov, enter CDC in the email Subject , and include the following "one" line in the Body of the email: signoffMMWR-MEDIA NIH-001767 From: Date: To: Bee: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 17 Feb 2020 20:16:44 +0000 Tabak, Lawrence (NIH/OD) [E) Marston, Hilary (NIH/NIAID) [E] RE: Larry, does NIH have a single point person through which all Coronavirus intel bu bbles up? Larry: Thanks for the note . (b)(5) 5> The person who CbH --------------------------usu a11y subs for me when I cannot be on a call or at a meeti ng is Hilary Marston . She is up to speed on virtually all this stuff and is the name that you should send to Paul. You can t ell Paul that he should channel everything t hro ugh m e and I can turf to Hilary when necessary and appropriate. Hilary is right here in my office and is very close to me. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-ma i l and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Tabak, Lawrence (NIH/OD) [El Date: Monday, February 17, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]------~= (b)( > Subject: Fwd: Larry, does NIH have a single point person th rough which all Coronav irus intel bubbles up? -------- Tony Do want this to be one of your folks or me? Thanks Larry NIH-001820 Sent from my iPhone Begin forwarded message: From: "Mango, Paul (HHS/10S)" Date: February 17, 2020 at 2:45:52 PM EST To: "Tabak, Lawrence (NIH/OD) [E]" <------- (b)(6)> =(b.., H=6) Subject: Larry,does NIH have a single point person through which all Coronavirusintel bubbles up? Larry- we are trying to integrate some of the department communications channels. Dr Fauci is on just about every call, but do you have someone else as well who is representing NIH and would be aware of any developments? Sent from my iPhone NIH-001821 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 15 Feb 2020 18:57:22 +0000 Harrison, Brian (HHS/10S) FW: WaPo - fact check on coronavirus story FYI. See below. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Saturday, February 15, 2020 1:50 PM To: Oakley, Caitlin B. (OS/ASPA)--------,;-= Cc: Stecker, Judy (OS/IOS) Cb)( ; Conrad, Patricia (NIH/NIAID) [El (b)(6) >; Billet, Courtney (NIH/NIAIO) [El (b)(6) Subject: RE: WaPo - fact check on coronavi rus story --------- Caitlin/Judy: I had a long and good conversation with Yasmeen Abutaleb and went over (and countered) all of the issues that had any negative connotations for the Secretary and/or the President. I spoke on the record and gave her permission to use my quotes as she so wishes. Mission accomplished. Best regards ., Tony Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001858 FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Oakley, Caitlin B. {OS/ASPA) (b)(6) Date: Saturday, February 15, 2020 11:31 AM To: Fauci, Anthony {NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Stecker, Judy (OS/1O5) (b)(6); Conrad, Patricia {NIH/NIAID) [E] Cb)( >; Billet, Courtney {NIH/NIA ID) [El (b)(6) Subject: FW: WaPo - fact check on coronavirus story --------- Dr. Fauci- Thank you fo r the chat. Here is the reporter's contact info and she is expecting your call. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334 -8387 c: (b) ( Yasmeen.Abuta leb@washpo st .com ---~~ ----- C aitlin B . Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) From: Abutaleb, Yasmeen Se nt: Friday, February 14, 2020 4:40 PM To: Oakley, Caitlin B. (OS/ASPA) CbH6J>; McKeogh, Katherine {OS/ASPA) (b)(6) Subject: WaPo - fact check on coronavirus story --------~~ Hey Caitlin and Katie, Happy Friday! I'm wo rking on a story about the coronavirus response, aim ing to publish tomorrow. The story is about how President Trump has praised China and President Xi, but that has made some of his advisors uncomfortable given the lack of transparency from China and the inability to get CDCscientists in to the country. We also have some details about the response and the task force , and some disagreements that have arisen. I've listed the points we have in the story that pertain to HHS- would you be able to take a look, let me know if there are any issues and potentially provide a comment? I included some quotes from Sec. Azar's interviews on Friday with CNN and CNBCbut also happy to include a quote from the agency. NIH-001859 I realize I'm sending this at the end of the day, so would it be possible for you to get back to me by 1 pm tomorrow? Let me know what works on your end. Thanks so much. • President Trump has lavished praise on China and its ruler, Xi Jinping, for its handling of the growing coronavirus outbreak - a posture some in his administration are growing increasingly uncomfortable with as his advisors remain concerned about China's transparency and handling of the epidemic . • Trump's praise towards Xi has irked some advisors, who say those comments and others about how the virus wil l likely behave reflect how the president is being briefed, underscoring tensions within the admin istration over its handling of the outbreak and the message it should be sending to the American public. • Worries about the market and tenuous negotiations with China over a trade deal have played a large role in influencing Trump 's friendly posture . • Trump has told advisors he does not want the administration to do or say anything that would further spook the markets, but remains worried that any large-scale outbreak in the U.S. could hurt his reelection bid . • For weeks, the adm inistration's messaging was that the th reat to the American public remained low and the virus was not spreading within communities. But some advisors pushed for a more balanced message because they expect there to eventually be some commun ity spread as the outbreak grows, and the administration has since adjusted its message to reflect that. • In an effort to keep Trump calm and restrained, Azar has been briefing the president that "everything is under control, totally under control," which has kept Trump from doing or saying anyth ing drastic. • HHSofficials have also told Trump that the number of infections could go down in the spring when it gets warmer, which is mainly an educated guess. • Some officials have complained that Trump's comments emanate from his briefings with Azar, who they say has sought to control the response . He has told other doctors , including Anthony Fauci, not to get too far into the details of the virus and outbreak with Trump . Instead, Azar has instructed doctors to let him handle it. • Azar has also wanted to be the one to announce major updates about the administ ration's response to the virus . On Thursday, he briefed the Senate Finance Committee that the CDC would use public health labs in five cities that normally test for infl uenza to also test for coronavirus, taking state health officials by surprise. • Some officials said the response has become smoother and better coordinated in recent weeks. Yasmeen Abutaleb The Washington Post Health policy reporter o: 202-334-8387 c: ---~ @yabutaleb7 ----- (b ~)~(6) = NIH-001860 Fauci, Anthony (NIH/NIAID) [E) Sat, 22 Feb 2020 21:07:26 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDID/NCEZID/DGMQ);Jernigan, Daniel B. (CDC/DDID/NCIRD/1D) Subject: RE: Wpost: New developments suggest coronavirus incubat ion cou ld be longer than 14 days, as global infections rise From: Date: Sou nd s good to me. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Messonn ier, Nancy (CDC/DDID/NCIRD/OD) Date: Saturday, Februar y 22, 2020 4:06 PM ------ To: Fauci, Anth ony (NIH/NIAID) (E] (b)(6) --=-<~ (b)(6) Cc: Redfield, Robert R. (CDC/OD) (b)(6)>; Cetron, M arty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Jernigan, Daniel 8. (CDC/DDID/NCIRD/ID) (b)(6)> Subject: Re: Wpost: New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise ------ (b) (5) Soundgood? From: Fauci, Anthony (NIH/N IAID) [E] (b)( > Date: Saturday, February 22, 2020 3:12:02 PM To: Redfield, Robert R. (CDC/OD) (b)(6)>; Messonnier, Nancy (CDC/DDID/NCIRD/OD) _, Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)(6)>; (b)(6)> Subject: FW: Wpost : New developments suggest coronavirus incubation could be longer than 14 days, as global infec tion s rise _____ NIH-001620 Folks: (b) (5) Ton y Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6) From: Folkers, Greg (NIH/ NIAID) [E) Date: Saturda y, February 22, 2020 10:52 AM Subj ect : Wpost: New developments suggest coronavi rus incubation could be longe r than 14 days, as global infections rise New developments suggest coronavirus incubation could be longer than 14 days, as global infections rise NIH-001621 Medical workers in protective suits gather Friday at a temporary hospital at Tazihu Gymnasium in Wuhan in central China's Hubei province. (AP) By Anna Fifield, M in Joo Kim and Simon Denyer Feb. 22, 2020 at 10:17 a.m. EST There are new indications that the incubation period for the virus could be longer than the currently believed 14 days, with patients testing positive after much longer quarantine periods. This development came as infections rose in South Korea, Japan, Iran and It aly and the head of the World Health Organization warned that the w indow for stopping the epidemic was narrowing . Here's wh at w e know: • Chinese leader Xi Jinping has been advised that the situat ion in Wuhan "remains grim and com pie><." • South Korea and Japan both reported a sharp spike in cases Saturday, with the number of cases in South Korea doubling in a day. A fifth person died in Iran from the virus, while Italy now has 50 confirmed cases, making it the largest hot spot in Europe. • China reported only 397 new cases Saturday, as the rate of increase continued to decline, but an addit ional 109 people have died . There continues to be a great deal of skepticism about China's numbers as t he criteria for diagnosing coronavirus keep changing. • A team of international epidemic experts had Wuhan added to their itinerary in China, following quest ions about why they wouldn't go to the center of the coronavirus outbreak tha t has caused more than 2,000 deaths in the country . • Scientists in China said they had isolated coronavirus strains in urine , raising the possibility that it might be transmissible that way, as well as through feca l matter and respiratory droplets . NIH-001622 BEIJING - Scientists are studying reports that the incubatio n period for coronavirus could be longer than the cur rent ly believed 14 days, potentially casting doubt on current quarant ine crite ria for contain ing the vir us amid an increasingly urgent effort to stop the epidemic from spreading in northeast Asia and across the world. South Korea and Japan both reported a sharp spike in cases Saturday, wh ile in China, an addit ional 109 people died and a fifth person died from the virus in Iran. Italian authorities on Saturday said the country was seeing a sudden rise in coronav irus cases, w ith roug hly 50 confi rmed in the past two days - an outb reak that represents the largest yet across Europe. Meanwhi le, scientist s in China reported indications that the virus might be transmissib le through urine. A team of experts from the World Health Organization was due to arr ive Saturday in Wuhan, the epicente r of the coronav iru s outbreak. WHO director-gene ral Tedros Adhanom Ghebreyesus on Friday stressed the urgency of conta ining the spread of the coronavirus, after cases were reported earlier in Iran and Lebanon. "Although the w indow of opportun ity is narrowing to conta in the outbreak , we still have a chance to contain it ," he told reporters in Geneva. "If we don't, if we squander the opportunity, then there w ill be a serious problem on our hands." Chinese leader Xi Jinping, who has not visited Wuhan since the outbreak began, was briefed t hat the situation in the city and in surround ing Hubei prov ince "rema ins grim and comp lex," according to a repo rt by the official Xinhua News Agency published Saturday. "The nationw ide inflect ion point of the epidemic has not yet arri ved," the report said after a meeting of Communist Party leaders. China' s National Health Commission reported Saturday that 397 new cases of coronav irus had been diagnosed Friday, tak ing the tota l to more than 76,000. The rate of infection outside Hubei appears to have slowed markedly, althoug h there has been a great deal of conf usion about the statistics th is week as officials have repeatedly changed the crite ria for confi rming cases. Among the new cases discovered Friday were a 70-year-old man in Hubei who was confirmed as infected after 27 days in isolation, while a man in Jiangxi prov ince tested posit ive after 14 days of entralized quarantine and five days of isolation at home. On Thursday, autho rit ies reported that a man in Hubei had tested positive for coronav irus after what appeared to be a 38-day incubation period w ith no symptoms. Coronaviruscasesin South Korea skyrocket; casestriple in Japan In Seoul, the Korea Centers fo r Disease Control and Prevent ion reported Saturday that 229 addit ional cases of the coronav irus had been detected, tak ing the tota l to 433, more than doubling in the space of a day. This makes it the worst -affected count ry outs ide China. "Apart from the Diamond Princess cruise ship, [Sout h] Korea now has the most cases outs ide China, and we're work ing closely w ith the government to f ully unde rstand the transmission dynam ics that led t o th is increase," Tedros said. The majo rity of the new cases have been traced to existing clusters at a churc h in southern city of Daegu and a hospital in nearby Cheongdo County, according to the KCDC. The South Korean government has designated Daegu and surro unding Nort h Gyeongsang prov ince as "special care zones" whe re conta inment efforts and support will be concentrated. More than half of South Korea' s cases are connected to Daegu branch of the Shincheonj i Church of Jesus the Temple of t he Tabernacle of the Testimony . Since members of the chu rch attended a fune ral at nearby Cheongdo Daenam hospital , 111 coronavirus cases have been repo rted the re, includ ing two patients w ho died from the virus . NIH-001623 The mass infection at the hospital is centered on its locked psychiatric ward, where a confined environment could have aggravated transmissions, said Jung Eun-Kyeong, director of the KCDC. A man in his 40s was found dead at his home in city of Gyeongj u, east of Daegu, after becoming infected with the virus. He is the third person to die from the virus in South Korea. Trump was not t old coronavirus-infected Americans would be fl ow n home from cruise ship In Japan, the number of coronavirus cases rose to 121 on Saturday, more t han tripling in a week. That number excludes the 634 people on board the Diamond Princess who contracted the virus. One of the latest cases was a teacher in her 60s at a public junior high school east of Tokyo, who complained of nausea whi le working. The mayor of Chiba city said the school w ill be closed until Wednesday, public broadcaster NHK reported. The teacher had not traveled abroad in the past two weeks and has no record of having been in contact with a known infected person, underl ining the fact that the virus is now spreading almost invisibly throughout the country, experts say. Quarantines in effect in parts of Italy amid sudden spike in cases As numbers suddenly rose in Italy, the government has scrambled to contain the new outbreak, asking some 50,000 people to stay indoors and suspending all public events - including religious ceremonies and school - in 10 small towns to the south of Milan. Until a few days ago, Italy had seen only three confirmed infections, including a pair of Chinese tourists. "There is quite an evident contagion, a very strong one," said Giulio Gallera, health chief of the northern Lombardy region, which has seen the majority of the cases. Italian officials on Friday attributed the country's first death to the coronavirus, and on Saturday said that a 77-year-old woman had also tested positive for the virus after being found dead in her home. But Italian authorities said the woman suffered from other health conditions, and were unsure if it was the virus that had killed her. As of Saturday afternoon, there were 39 confirmed cases in the prosperous Lombardy region, which includes the country's financial hub, Milan . There were another 12 cases in the neighboring northern region of Veneto. The regional president of Veneto, Luca Zaia, said it is becoming harder to figure out how the virus is jumping from one place to the next . "It goes to show you that having other cases of contagion is absolutely possible," Zaia said. According to Italian media reports , one of the first peop le to come down with the virus was a 38-yearold who'd had dinner with somebody who had j ust come back from China. But some three wee ks passed between that dinner and the time the man came down with a fever. In between, he ran a halfmarathon, played soccer and traveled to several towns, according to La Repubblica, a maj or Italian daily . Iran, meanwhile, announced its fifth death from t he virus, raising the country's overa ll total confirmed cases to twenty eight . Efforts to clear the Diamond Princess cruise ship continue Meanwhile, tests are continuing on the crew members on board the Diamond Princess. At least 74 crew members have so far been found to have the virus. All of the passengers have now been tested and almost all have left the ship, either to go home if they tested negative, to local hospitals or government facilities if they have the virus, or back to their home countries. Some passengers were asked to stay on board to serve an additional quarantine if their cabin mate contracted the virus, but this group is also disembarking Saturday to serve out the rest of their quarantine in a government facility, local media reported . In China's 'w ar' on coro navirus. hospita ls turn away ot her pat ient s - w ith dire result s NIH-001624 More than 200 port calls in Japan by international cruise ships have been canceled since the beginning of February due to the coronavirus outbreak, a Kyodo News survey showed Saturday, with the lost revenue from passengers coming ashore dealing another blow to Japan's weak economy . Controversy continues to simmer about the infection control procedures on board the ship, after a doctor complained on Tuesday about "chaotic" and scary conditions on board . Six people working on the boat or with the passengers, including four government officials, a medic and an ambulance driver, have contracted the virus. Media reports questioned why about 90 government officials who worked on the ship have returned to work without being tested for the coronavirus . Asked about this, Health Minister Katsunobu Kato said the government is "trying to confirm what operations staff were involved in specifically." Amer ican woman in Malays ia declared free of coronavirus The 83-year-old woman who tested positive for the coronavirus when she arrived at Kuala Lumpur airport after disembarking in Cambodia from the MS Westerdam cruise ship has recovered, Malaysia health authorities said Saturday. The woman "is showing good improvement and signs of recovery, however, she is still being mon itored and managed in hospital for a slight cough," Malaysia's director general of health, Noor Hisham Abdullah, said in a st atement. The woman repeatedly tested negative while on board the ship and when she disembarked in Sihanoukville, then twice tested positive wh ile transiting in Kuala Lumpur airport on Feb. 15. That set off a global scramble to track the hundreds of other passengers who had also disembarked then boa rded planes bound for home. The woman was taken to a hospital and given antiviral treatment and supplementary oxygen, and she showed improvement after 72 hours of treatment initiation, Abdullah said. Two more tests, conducted 24 hours apart, both came back negative for coronavirus. But the U.S. Centers for Disease Control and Prevention cast doubt on whether the woman was ever infected, saying she "never had coronavirus to our knowledge ." "I have confirmed that all the passengers were tested, and they have come back negative for coronavirus, including the person who initially tested positive ," USAToday quot ed CDCspokesperson Richard Quartarone as saying. The woman " may have had a respiratory ill ness, but if she did, it was not covid- 19," he said, using the official name for the virus. Cambodia's Ministry of Health had previously cleared the 747 crew members who were still on board the Westerdam and the 781 passengers who were still in the country of coronavirus infection . Chinese scientists isolate coronavirus strains in urine as WHO prepares visit Separately, scientists in China are continuing to study how the virus is transmitted . A research team led by renowned Chinese pulmonologist Zhong Nanshan had isolated live coronav irus strains in urine samples from infected patients, Zhao Jincun, a respiratory expert at the State Key Laboratory, told reporters in Guangdong on Saturday. The team of scientists had previously said the virus, in addition to being carried in respiratory drop lets, appeared to be transmissible through fecal matter, underscoring the need to practice good hand washing as a preventive measure . Zhao did not directly say that the virus could be transmitted through urine, simply noting that the strains had been isolated and that this had implications for public health control. They are cont inuing to work on isolating the virus and on a cure, the Guangzhou Daily reported. But he said people should pay more attention to personal and family hygiene to prevent the spread of the virus and recommended frequently washing hands, closing the toilet lid before flushing and making sure bathroom drains are not blocked. NIH-001625 WHO experts have also been on an investigative mission in China this week, holding meetings in Beijing and traveling to the prov inces of Sichuan and Guangdong. But they had not been scheduled to travel to Wuhan , where the outbreak began at a live animal market and which remains under strict lockdown in an effort to contain the virus. This had led to speculation that the Chinese government, which has come under fire for its slow response to the outbreak and where medical workers are stretched to the limit, did not want the experts to visit. But the WHO said late Friday that the experts would be travel ing to the center of the outbreak on Saturday, although they gave no further information about their itinerary . Kim reported from Seoul and Denyer from Tokyo. Lyric Li in Beijing, Akiko Kashiwagi in Tokyo and Chico Harlan and Stefano Pitrelli in Rome contributed reporting. Two Beijing hospit als qua rantine d amid fears coronav irus infect ions w ill spike in t he capita l Confusion mount s over China' s count ing met hods as coronav irus numbers swing w ildly Coronavirus claims lives of two passengers fr om Diamond Princess cruise ship, Japanese med ia says Today1scoverage from Post corr espondents around t he wo rld Like Washingt on Post Wo rld on Faceboo k and stay updat ed on fo reign news Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIATD, NTH, HHS, or the U.S. government. NIH-001626 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Sat, 22 Feb 2020 18:35:29 +0000 Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) RE: COVID-19 Jono : Ma ny t hanks for yo u r kind note. Much appreciated. I ho pe th at all is we ll w ith yo u. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Mermin, Jonathan (CDC/DDID/NCHHSTP/OD) Se nt : Saturday, February 22, 2020 1:14 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6)> Subject: COVIO-19 ------ CbH > ------=--c= Tony: I just wanted to send you a quick note of compliment. I have seen and heard you speak on COVID-19 over the past few weeks, eloquent ly, accurately, and as definitively as the data allow. Outstanding work . Best, Jono NIH-001651 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 21 Feb 202011:59:09 +0000 To: Cetron, Marty (CDC/0010/NCEZID/DGMQ) ;Collins, Francis (NIH/OD) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Charles, Julia (CDC/00/0CS);Eidex, Rachel Barw ick (CDC/0D1D/NCEZID/DGMQ) Subject: RE: Infectious d isease advice for NSO Asia tour Date: Thanks, Marty . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Cente r Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) Se nt : Friday, February 21, 2020 6:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( ------ (b)( > -------= = --------- (b)( ; Collins, Francis (NIH/OD) [El Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Charles, Julia (CDC/00/0CS) (b)( ; Eidex, Rachel Barwick {CDC/DDID/NCEZID/DGMQ) CbH > Subject: Re: Infectious disease advice for NSOAsia tour ------ Tony and Francis Happy to be a POCfo r Deborah . She can text me (b)(6)and we can arrange a time to speak. My cell recept ion in EOCnot great. Alternative ly EOCcan track me down (b)(6) Email pretty clogged these days ... Best, MSC Get Out loo k for iOS -------- CbH > -------- (b)(6) From: Fauci, Anthony (NIH/N IAID) [El Se nt: Friday, February 21, 2020 5:46:50 AM To: Collins, Francis (NIH/OD) [E] NIH-001694 _____ ..... Cc: Cetron, Marty (CDC/DDID/NCEZID/DGMQ) (b)( >; Conrad, Patricia (NIH/NIA ID) [E] (b)(6) Subject: RE: Infectious disease advice for NSO Asia tour Francis: (b)(5) The best person in the wor ld for this is Marty Cetron at the CDC. ------------am copy ing him on this e-mail. Perhaps he can direc tly get back to you. (b) (5) Best, Tony -----Original Message----(b)(6) From: Collins, Francis (NIH/OD) [E] Date: Friday, February 21, 2020 5:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: FW: Infectious disease advice for NSO Asia tour --------------=-:-:= --------- Hi Tony, See below from Deborah Rutter, t he head of the Kennedy Center . ------------ (b) (5) Who would you recommend at NIH or CDCto be a contact? Francis -----Original Message----From: Rutter, Deborah F. Date: Thursday, February 20, 2020 5:59 PM To: Collins, Francis (NIH/OD) [El (b)( > Cc: Ginstling, Gary Subject: Infectious disease advice for NSOAsia tour Dear Francis As you may know, the National Symphony Orchest ra has long had an Asia your on its schedule for March this year, leaving in just two weeks or so. The China portion of the tour was cancelled a few weeks ago but the Japan portion of the trip has been sustained. Now, with increased focus on Japan, some of the members and our management are looking for addit ional advice on travel concerns and any infectious disease warning/direction. Would you have someone amongst your brilliant colleagues who could be a resource to our team? I have included Gary Ginstling on this email as he is our Executive Director of the NSO. Thank you so much for any direction you can offer us! Deborah NIH-001695 This e-mail message is intended only for the recipient(s) named above. This message may contain trade secrets, attorney -client communication, or other privileged and confidential information . Any review, retransmission , dissemination, reproduction or other use of , or taking of any action in reliance upon , this information by persons or entities other than the intended recipient is prohibited. If you received this in error , please contact the Sender and delete the material from any computer . NIH-001696 From: (b)(6) Date: Tue, 18 Feb 2020 15:41:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: Lunch with AMB at Thai Residence on 27 Feb or 4 March To: Subject: Let us discuss. Begin forwarded message: (b)(6) From: "Wolfe , Mitchell (CDC/OD)" ------Date: Februa ry 18, 2020 at l :08:55 PM EST To: "Fauci, Anthony (NIH/NIAID ) [E]" -------~~ Cc: "Conrad, Patricia (NIH/NIAID) [E]" (b)( Subject: F,v:Lunch with AMB at Thai Residence on 27 Feb or 4 March Tony, The Thai Ambassador has invited you, and CDC, to lunch at his residence either 27 Feb or 4 March. They didn't have your contact and asked (per below) if I could contact you to ask. Dr. Redfield is in Washington, DC on 27 Feb and I will ask if he wants to attend. If you or your staff can let me know, I will get back with them. Best regards, Mitchell Wolfe, MD, MPH RADM, USPHS Chief Medical Officer, Office of the Director Centers for Disease Control and Prevention Ph: (b)(6) ----- From: Panupat Chavananikul Date: Tuesday, February 18, 2020 12:42 PM To: Wolfe, Mitchell (CDC/OD) (b)(6) Cc: Chuliepote lsarankura Na Ayudhaya Subject: Lunch with AMB at Thai Residence on 27 Feb or 4 March Dear P Mitch krub, Ref: invita t ion for Lunch on 27 Feb OR 4 March 1. Hope all is well with you. Hopefully you had some rest last weekend. Since you were living in Thailand for a while you must be missing authentic Thai food . Ambassador Thani NIH-001780 w iould like to extend his invitation to you and CDC colleagues to have lunch at Thai residence either on Thursday27 Feb or Wednesday4 March at 12.30 pm. His residence located at (b)(6) You may invite your colleagues who involve in Coronavirus or Thailand, and please let me know their name and ranking as we ll as your available date. For the Embassy's side, there will be Ambassador+ Ms. Chuliepote +me+ and some of our colleagues. 2. Also, Ambassador Thani and I attended Dr. Tony Fauci's briefing, organized by NSC, on Feb 6., but unfortunate ly we didn't have much time to talk to him. Dr. Fauci also received Prince Mahido l award back in 2013 . Ambassador would also like to have him join our lunch at his residence as we ll. Is it possible that you may reach out to him to see whether he can have lunch with us or not, OR you may provide me his contact detai ls. Thank you krub &Best wishes, Panupat (boat) Mr .Panupat Chavananikul Counsellor (Consul) Royal Thai Embassy Cell Cb)(6) Work 202 640-5308 NIH-001781 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAI0) [E) Tue, 18 Feb 2020 14:57:27 +0000 Redfield, Robert R. (CDC/OD) RE: Severity Assessment for U.S. Response - CDC Severity Assessment for U.S. Response - CDC.docx Bob: See my minor tra cked edits. Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Redfield, Robert R. (CDC/OD) Date: Tuesday, February 18, 2020 9:35 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b) (6) _,(b __)-,(6) = Subject: Fwd: Severity Assessment for U.S. Response - CDC Take a look ?edits thoughts Or. Robert Redfield From: Jernigan, Daniel B. (CDC/DDID/NCIRD/ID) (b)(6) Date: Monday, February 17, 2020 10:48:48 PM To: Redfield, Robert R. (CDC/OD) (b)(6) Cc: Schuchat, Anne MD (CDC/OD) CbH6J> ; Cetron, Marty (CDC/DDID/NCEZID/DGMQ) CbH6J>; Butler, Jay C. (CDC/DDID/O0) CbH6J> Subject: Severity Assessment for U.S. Response - CDC ------ Dr. Redfield: Here is the severity assessment in response to your request from yesterday. Take a look and see if this addresses your request. Dan NIH-001784 From: Date: To: Cc: Hilary (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 19 Feb 2020 12:03:04 +0000 Marks, Peter;Schuchat, Anne MD (CDC/OD) Cho, David S (CBER)(FDA/CBER);Munster, Vincent (NIH/NIAID) [E];Marston, RE: Covid-19 Survival on Surfaces Peter: Vincent Mun ster at NIAi D's RML has done work on thi s. I am copying him on thi s e-mail. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marks, Peter Cb) ( > Date: Wednesday, February 19, 2020 6:41 AM To: Schuchat, Anne MD (CDC/OD) (b)(6)'>; Fauci, Anthony (NIH/NIAID) [E] (b)(6) --------- Cc: Cho, David S (CBER)(FDA/CBER) Subject: Covid-19 Survival on Surfaces (b)(6) Dear Anne and Tony, I am sorry to bother you, but I am hoping that you can direct me to anyone at NIAID or CDCwho is work ing on the survival of Covid-19 on surfaces. This could include shipping boxes, but also on various products and other perishab le items. The food safety people here at FDA are quite concerned about the latter, given published reports of differential coronavirus surv ival on various surfaces. If it turns out that this has not been evaluated, or is not in the process of being evaluat ed, we are happy to work on this in our BSL-3 labs, which are now in receipt of the v irus. NIH-001763 Thanks so much for any direction that you can provide. Best Regards, Peter NIH-001764 Fauci, Anthony (NIH/NIAID) [E) Sat, 15 Feb 2020 12:55:47 +0000 To: Gilman, James (NIH/CC/OD) [El;Collins, Francis (NIH/OD) [El;Gottesman, Michael (NIH/OD) [E);Tabak, Lawrence (NIH/OD) [El;Schwetz, Tara (NIH/OD) [El Cc: Holland, Steven (N IH/NIAID) [E);Johnson, Alfred (NIH/OD) [E);McGowan, Colleen (NIH/OD/ORS) [El;Schmitt, James (NIH/OD/ORS) [El Subject: RE: COVID-19 messaging From: Date: (b) (5) From: Gilman , James (NIH/CC/OD) [El (b)(6) Sen t : Friday, February 14, 2020 11:32 PM ----- ~= To: Collins, Francis (NIH/OD) [El (b)(6)> ; Gottesman, Michael (NIH/OD) [El (b)( ; Tabak, Lawrence (NIH/OD) [El (b)(6); Schwetz, Tara ":": (N"".".' l~ H/-:-:: 0:--: D~) ":": [E~] ====~__,_., (b).,..; (6) = >; Fauci, Anthony (NIH/N IAID) [E] CbH > Cc: Holland, Steven (NIH/NIAID) [E] CbH6J>;Johnson, Alfred (NIH/OD) [E] Cb)( ; Schmitt, (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] James (NIH/OD/ORS) [El Subject: Re: COVID-19 messaging (b)(6) (b) (5) Jim From: "Collins , Francis (NIH/OD) [El" Date: Friday, February 14, 2020 at 8:04:30 PM To: "Gottesman , Michael (NIH/OD) [E)"--------aa- CbH6J> Cb ~H=6J>, "Tabak , Lawrence (NIH/OD) [E]" (b)( >, "Fauci, Anthony (b)(6)>, "Schwetz, Tara (NIH/OD) [E]" (NIH/NIAID) [El" Cb)( > Cc: "Holland, Steven (NIH/NIAID) [El " (b)( >, "Johnson, Alfred (NIH/OD) [El" (b)(6)> , "McGowan, Colleen (NIH/OD/ORS) [El" (b)(6) , 11Schmitt, James (NIH/OD/ORS) [El" (b)(6), "Gilman, James (NIH/CC/OD) [El" ---:----:-~~==:::!....:--~~ ---------- (b)(6)> Subject: RE: COVID-19 messaging 1111Looping in Jim Gilman . FC (b)(6)> From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM NIH-001869 To: Tabak, Lawrence (NIH/OD) [El Cb)( >; Schwetz, Tara (NIH/OD) [El (b)(6); Collins, Francis (NIH/OD) --.--.~~==:!:...,__ _ ___;~~ [El (b)(6)>; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Holland, Steven (NIH/NIAID) [El CbH >; Johnson, Alfred (NIH/OD) [E] (b)(6); McGowan, Colleen (NIH/OD/ORS) [El (b)( >; Schmitt, James (NIH/OD/ORS) [El CbH6J> Subject: COVID-19 messaging We have had many requests for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send t his from OMS to all hands. Michael NIH-001870 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:23:37 +0000 Holland, Steven (NIH/NIAID) [E] RE: COVID-19 messaging COVID-smh - with Fauci edits .docx Steve: (b) (5) (b)(5) See m',' tracked edits. Thanks, Tony From: Holland, Steven (NIH/NIAID) [E] Date: Friday, February 14, 2020 9:06 PM To: Fauci, Anthony (NIH/NIAID) [E]-----______ Subject: FW: COVID-19 messaging --------- (b) (6)> ~= Cb > _<_ > Tony, Could you please look at the attached and make any edits you think would help . (b)(5) ~ (b)(5) Steve Director , Division of Intramural Research National Institute of Allergy and Infectious Diseases National Institutes of Health Bldg. 10/11N248 MSC 1960 Bethesda, MD 20892-1960 (b) (6)voice 301-480-4507 fax (b) (6) email ----- ----- Assistan t lab: Eva Portillo (b)(6) emai l (b) (6) voice ~==~~--- ----- Assistant to SD: Beth Schmidt NIH-001871 ---- (b) (6) (b)(6) voice (b)(6 )> From: "Gottesman, M ichae l (NIH/OD) [E]" Date: Friday, February 14, 2020 at 6:12 PM To: "Schmitt, James (NIH/OD/ORS) [E]" --------- -------~~ ..========;:-=-,;:-Cc: "Moss, Bradley (NIH/OD/ORS) [E)" Steven Holland (b)(6) --------- (b)( 6) (b)(6) Subject: Re: COVID-19 messaging (b) (5) Michael · This can wait until next week. ---------------~= From: "Schmitt, James (NIH/OD/ORS) [E]" Date: Friday, February 14, 2020 at 6:07 PM To: "Gottesman, Michae l (NIH/OD) [E]" (b)(6) Cb)( > Subject: FW: COVID-19 messaging I meant to copy you on this Michael. Jim From: Schmitt, James(NIH/OD/ORS) [El Date: Friday, February 14, 2020 6:07 PM ------~= To: Moss, Bradley (NIH/OD/ORS) [El (b)(6) --------- (b)(6)>; Bailin, Heike Cc: Newcomer, Derek (NIH/OD/ORS) [El (b)(6) (b)(6)>; Wheeland, Daniel (NIH/OD/ORF) ----------McGowan, Colleen (NIH/OD/ORS) [E) (NIH/OD/ORS) [E) Subject: FW: COVID-19 messaging [E) (b)(6); (b)(6)>; Tosten, Timothy (b)(6) Hi Bra d, It sounds like Dr. Gottesman wants this sent from OMS to everyone. I don ' t know how to do that. Can you help us with this and how soon can it be sent? I'm heading out of town and won ' t retmn to the clin ic until Tuesday . Dr. Bai lin will be in charge of OMS in my ab sence. Jim James M. Schmill, M.D., M.S. Medical Director Occupational Medjcal Service, DOHS NIH-001872 National In stitutes of Hea lth IOCen ter Drive Bethesda, MD 20892-1584 (b)(6) From: Gottesman, Michael (NIH/OD) [E] Date: Friday, February 14, 2020 6:03 PM To: Tabak, Lawrence (NIH/OD) (E] (b)( (b)(6); Collins, Francis (NIH/OD) [E) 7( N - l'."'" H/7 N- IA "".'" l-:D-:) :-: [E-:. ) ==:::::;.--~ (b "'~=(6)> ------- Cc: Holland, Steven (NIH/NIA ID) [E] (b)(6)> ~= >; Schwetz , Tara {NIH/OD) [E] (b)(6)>; Fauci, Anthony (b)(6)>; Johnson, Alfred (NIH/OD) (b)(6); McGowan, Colleen (NIH/OD/ORS) [E] Schmitt , James (NIH/OD/ORS ) [E] CbH6)> Subject: COVID-19 messag ing --------- [E] (b)( >; We have had many reques ts for additional guidance concerning staff potentially exposed to COVID-19. OMS has prepared the attached message which has been reviewed by Steve Holland and HR. The intent is to send this from OMS to all hands. Michael NIH-001873 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 15 Feb 2020 02:08:57 +0000 To: Cassetti, Cristina (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C);Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert {NIH/NIAID) [E);Lerner, Andrea (NIH/NIAID) [El Subject: RE: Rapid instrument-free NAAT for COVID-19 Attachments : VisbyMedical_ TechWatch_Feb2020_nCoV_NIH.pdf See attachment as per prior e-mai l. From: Fauci, Anthony (NIH/NIAID) [E) Date: Friday, February 14, 2020 9:08 PM To: Gary K. Schoolnik (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) (El (b)(6 h ; Barasch, Kimberly (NIH/NIAID) [CJ (b)(6) ; Marston, Hilary (NIH/NIAID) [E (b)(6)>; Eisinger, ---:---:---:---'""'.""":''"""."::==.:.---:...._~ ~ Robert (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E) CbH ; Cassetti, Cristina (NIH/NIAID) [E] (b)(6)> Subject: RE: Rapid instrument -free NAAT for COVID-19 ---------- Gary: Thanks for the note. I would be happy to discuss this with you. Please have your office contact my Special Assistant, Patty Conrad, (copied here) to set up a mutually convenient time when we can chat. Best regards, Tony From: Gary K. Schoolnik (b)(6)> Date: Friday, February 14, 2020 6:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [E) Cc: Adam de la Zerda Subject: Rapid instrument-free NAATfor COVID-19 (b)(6)> (b)(6) Dear Tony , In addition to my role as a Stanford Medical School professor, I am the Chief Medical Officer of Visby Medical, a relatively new Silicon Valley diagnostics company focused on rapid detection of infectious agents. Visby Medical has developed a rap id (~25 min sample-to-answer) palm-sized, 40 cycle PCR (or RT-PCR) single-use device that does not requ ire an instrument; and then discarded or recycled . device is stable at room temperature it is used once, (b)(4) for up to two years and thus it could be deployed widely. NIH-001874 We are seriously considering using this platform to develop a rapid test to detect COVID-19. Proof of principles that have been achieved toward that end are our demonstration that the device can use two-step RT-PCRto detect influenza A and Bin NP swab samples. The main features of the device are described in the brief accompanying PDF. I write now because we are unsure, if we were to produce a COVID-19 device, how it would be deployed, by whom it would be used and who might be willing to purchase it. I would be very grateful if you might be able to speak briefly with me and my colleagues about these open questions. I am convinced this device can meet a major unmet need in clinical care and disease control for this epidemic and we, as a group, want to make a difference. Your advice would be invaluable as we weigh the risks and benefits of pivoting the company to this application. With all best wishes; I hope all is well with you and your family. gary Gary Schoolnik, M.D. Professor of Medicine Stanford Medical School Attending Physician (Internal Medicine , Infectious Diseases) Stanford University Hospital Chief Medical officer Visby Medical NIH-001875 From: Date: (b)(6) Fri, 14 Feb 2020 18:45:53 -0500 To: Julia Belluz Re: call Subject: My pleasure! On Feb 14, 2020, at 6: 10 PM, Jul ia Belluz wrote : Thank you so much for making the time to comment at what I know is a crushingly busy time. As usual don't hesitate to ping if you have any fmther comments or questions! Julia https://wwv,, .vox.com/2020/2 / 14/2 l l 344 73/coronavirus -outbreak -singa pore-ussym ptoms-pan demic Sent from my iPhone On Feb 14, 2020, at 1:2 1 PM, Fauci, Anthony (NIH/NlAID) [E] Cb)(6) wrote: Julia: I j ust called you now (7:20 AM Washington, DC time) and got mvoice mail in German that I could not understand. You can call me at CbH6J Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mai l : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive Information. It shou ld not be used by anyone who is not the original intended recipient. If you have received this email in error please inform the sender and delete it from your mailbox or NIH-001878 any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001879 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 2020 21:09:40 +0000 Conrad, Patricia (NIH/NIAID) [E) RE:Your Expertise requested/COVID -19 Forum To: Subject: OK. Let us d iscuss. As long as it is remote ... Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- From: Conrad, Patricia (NIH/NIAID) [El Date: Friday, February 14, 2020 3:45 PM (b)(6) To: NIAID OD AM Subject: FW: Your Expertise requested/COVID -19 Forum Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informat ion in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representalives. NIH-001880 (b)(6)> From: Roache, Christina Date: Friday, February 14, 2020 3:38 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Subject: Your Expertise requested/COVID-19 Forum ------~~ !.=======~= --------- Dear Dr . Fauci, You have been kind enough to be a panelist on our Forums at the Harvard T. H. Chan Schoo l of Pub lic Health , and I wanted to see if you were available to participate remotely in a Fomm that we are organizing on March 2 about COVID -19. The Forum will live stream on the websites of The World and The Forum, as welJ as on Facebook and YouTube. The World will send a journa list to moderate and co-promot e. The Forum is called "The Coronavirus Outbreak: Tracking COVID-19", presented jointly with The World from PRX & WGBH. Should you agree to part icipate, we ask that you jo in us remotely from 11:40am-lpm ET on March 2; the actual live we bcast will be noon-lp m ET. We have been active is cover ing this outbreak . We did a high ly successfu l Facebo ok Live Q&A last week and are doing another Q&A next week. As a reminde r, Forum webcasts are one-hour long and are pan el discussions, typically with 3-4 pane lists, plus a moderator. As noted, these discu ssions are live streamed from our Leadership Studio at our school in front of a stud io audience (about 40 seats) and an onli ne audience. Anyone with an Int ernet connection can watch the live webcasts; no registration or fee is required. NIH-00188 1 Previous speakers in The Forum series have included Gina McCarthy , former EPA Administrator; Anthony Foxx, then U.S. Secretary of Transportation; Eric Holder, then U.S. Attorney General ; Kathleen Sebelius, then U.S. Secretary of Health and Human Services; Gordon Brown, former UK Prime Minister ; as well as numerous former governors and key public health policymakers and officials from a range of public and private sector entities. The Forum live webcasts are also streamed on The Forum website, where they are accompanied by a live chat and online commenting, and on Facebook and YouTube. These webcasts are later posted as on-demand videos to our site and to Harvard's Y ouTube and iTunesU channels . We also make available podcasts, transcripts and other materials. Collective ly, the programs and complementary content have resulted in nearly five million viewer engagements so far, and our website has received visits from more than 200 countries and territories and every U.S. state. Please share your thoughts when you are able . Cheers, ChristinaRoache AssociateDirector, Productionand Web, The LeadershipStudio HarvardT.H. ChanSchool of PublicHealth (b)(6) NIH-001882 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:23:04 +0000 Clayton , Janine (NIH/OD) [El RE: Sex differences in COVID-19 Not much at th is poi nt . ------------------------- (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Clayton, Janine (NIH/OD) [El Date: Friday, February 14, 2020 3:06 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Sex differences in COVID-19 ------------- (b)( > -:-::~ (b)(6) Hi Ton (b) (5) Janine NIH-001883 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 20:21:51 +0000 Richard Allen Johnson RE: 2020.02. 14 Friday Dick: Thanks for the note. I certainly appreciate your concerns about WHO. Not much sleep for me lately. Just like internship. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Allen Johnson ---------Friday, February 14, 2020 3:18 PM Date: To: Fauci, Anthony (NIH/NIAID) [E) ,------- (b)(6) --,. (b._.. )= c >; Richard Allen Johnson (b)(6) Subject: 2020.02.14 Friday Hi, Tony, I am very distressed by the Face of the WHO. Their publ ic face, their news updates, are of the quality of t hose of a third world country . I only hope that they function bette r than their news updates suggest. They need a wo rld class public relations firm. I am deeply concerned re Covid-19 in Ind ia (w ith a population of 1500 million) and Africa (pop ulation 100 million). News rep orts do not mention anything of th is pandemic wa it ing to happen. Hope that you are w ell and gett ing a good night' s rest. Best, Dick NIH-001884 From: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 2020 18:27:24 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: inhaled buformin for coronavi rus Date: To: Subj ect : (b)(4) Please han dle . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 E-mail : (b)(6l The information in this e-m ail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have re ce ived this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------------- From: Steven Lehrer Date: Friday, February 14, 2020 1:17 PM To: Fauci, Anthony {NIH/NIAID) [El Subject: ------ (b) (6) > CbH >; -------- --== (b) (6) > (b)(4) for coronavirus Erbelding, Emily (NIH/NIAID) [E) Dr. Fauci, (b) (4) Steven Lehrer, MD (b) (4) NIH-001887 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Fri, 14 Feb 202017:39:33 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE: for review: proposed responses for Ital ian med ia request Nice Job . I have made o ne mino r ed it in the fi rst response. Oth erwise, it is ready to go. Thanks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Routh, Jennifer (NIH/NIAID) [E] (b)( > Date: Friday, February 14, 2020 12:32 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6) >; Billet, Courtney (NIH/NIAID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El (b)(6 b Subject: for review: proposed responses for Italian media request ------~~ Dr. Fauci This is not urgent for today . A reporter from the Italian health website Pazienti.it reached out to you directly with questions about coronavirus vaccine development. I have drafted proposed responses for your review attached and pasted below. I will send the final responses to the reporter attributed to you. Coronaviru s vaccine: when will it be avail able? What are th e diffi culties? The National Institutes of Health is on track to test an experimental messenger RNA (rnRNA) vaccine in a Phase 1 clinical trial this spring. This first phase of clinica l testing will involve giving the vaccine to healthy adults in the United States to see if it is safe and if it can induce an immune response in recip ients . It is importa nt to realize that the development of investigat ional vaccines and the clinical testing to establish their safety and effectiveness takes t ime . A vaccine against the novel coronavirus will likely not be widely available for at least a year . NIH-001890 Couldthe Coronavirus mutate, if a vaccine cannot be found in time? We are learning more about the novel coronavirus every day . At this tim e, we are not awar e of any mutations that might affect vaccine development . Based on our exper ience w ith ot her coronav iruses, including SARS-CoVand MERS-CoV, it is unlikely - but not impossible - that the novel coronav irus will mutate in a way that would have an impact on the development of medical countermeasur es. We are conti nuing to mon ito r this . Will the vaccine be the solution against Coronavirus? A safe and effective vaccine would be an extremely v aluable tool to help stop the spread of in fection and prevent future outbreaks. However, proven public health practices of ident ifying cases, isolating patients, and tracing contacts must continue alongside a vaccination program. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communicatio ns and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/ HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: (b) ~ Di sc lai mer: The informat ion in this e-mail and any of its attachment s is confide ntial and may cont ain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived th is e-mai l in error please inform the sender and delete it from your mai lbox or any other storage dev ices . The National Institute of Alle rgy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not expressly made on behalf of th e N IAID by one of its representatives. N IH-00189 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [El Fri, 14 Feb 202017:23:43 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: (b)( 4) Please han dle. Tha nks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -----------------::-::-=, From: Hardham , John M Date: Friday, February 14, 2020 9:15 AM To: Fauci, Anthony {NIH/NIAID) [El Subject: (b) (4 (b)(6)> -------- (b)((;)> Tony: It was good to see you again at the ASM Biothreats Conference. We had worked toge t her on t he Medical Counte rmeasure Init iative when I was the Medical Officer for the DOD Chem Bio Program (under ASDAnd rew Weber) several years ago. (b) (4) If you or your staff have any interest, please feel free t o reach out to me. Hope you have a wonderful day ! John NIH-001892 John M . Hardham , Ph.D. I Resear ch Director , Global Biologics Research Director , Zoetis Center for Transboundary and Emerging Diseases Zoetis I 333 Portage Street, KZO-300-204 .3, Kalamazoo , Ml 49007 Office : (b)(6) I Mobile (b)(6) I (b)(6) Visit Us: zoetis .com zgetis FORANIMAlS. FOR HEAlJH. FOR YOU. Erne -- NIH-001893 ectious Diseases First coknow.Fasttomarket From: Date: To: Cc: (NIH/NIAID) [E] Fauci, Anthony (NIH/ NIAID) [E) Fri, 14 Feb 2020 15:52:49 +0000 Strauss, Nico le Mascola, John (NIH/VRC) [E];Graham, Barney (NIH/VRC) [E];Conrad, Patricia Subject: RE: (b) (4) ---------------------- (b) (4) I Nicole: Thank you for your note and interest. I will copy on this e-mai l Ors. John Mascola and Barney Graham of our Vaccine Research Center who are developing the vaccine with Moderna so that they can respond directly to you. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: Cb)(6J FAX : (301 496-4409 E-mail : (b)(6J The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . ---------- (b)( From: Strauss, Nicole Date: Friday, February 14, 2020 10:37 AM To: Fauci, Anthony (NIH/NIAID) [E] .,;...__;_ __ .:......:....:..:::===-;:;;::;---- (b)(6J Cc: Weisser, Karen (b)(6J ------~~ Subject: _____________________ Cb _>_C4_, ) I ___ Cb _>_C4_) Dear Dr . Anthony Fauci, (b) (4) NIH-001894 Best regards, Nicole • CentreOne Nicole Strauss Pipeline Development & Innovat ion Lead T: (b)(6) I M: (b)(6) 500 Arcola Road, Collegeville, PA 19426 Website I Linkedln NIH-001895 From: Date: To: Subj ect : Attac hment s: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 14:22:00 +0000 (b)(6) Greg Folkers NEJM NEJM Editorial - Fauci et al -1st draft - 02-13-2020.docx, nejmoa2001316.pdf ---------- Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-001896 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Fri, 14 Feb 2020 03:20:06 +0000 Embry, Alan (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El RE: Instit utional request for information Thanks, Alan. From: Embry, Alan (NIH/NIAID ) [E]_______ Cb _H_6) Date: Thursday, February 13, 20 20 10 :18 PM To: Fauci, Anthony (NIH/NIAID) [E] -----(b =)""'(6) = >; Fried, Linda P. (b)(6) >; Redfield, Robert R. (CDC/OD) (b)(6) ----------- Cc: Conrad, Patricia (NIH/NIAID) [E] CbH ; Goldman , Lee Cb) (6) >; Booth, Jane Cb) ( >; Katznelson, Ira I. (b)( 6) >; Marston, Hilary (NIH/NIAID) [El CbH6) ; Eisinger, Robert "'!"' (N- IH - /':"" N-IA--10 -:-)-:[E-:-: ) ::::::=====-_;,_-~(b"""' )( = 6) ~========-.,;-- Subject: RE: Institutional request for information Dear Dr. Fried, Answers to your questions are below . 1. Is th e CDC or NIH over seeing the distrib ution of th e live viru s in the U.S. ? There is an interagency working group convened by the Assistant Secretary for Preparedness and Response oversee ing samples, and NIH and CDCare central to this . Virus is being deposited in BEi Resources (a NIAID contract resource ) for characterization, growth and distrib ution. The WA isolate is available now and a Hong Kong isolate may be added soon. 2. Will you be the sole sour ce of dist ribution in the U.S., or will institut ions be permitte d to obt ain it directly fr om oth er sources? Assuming appropriate permits are in place, there is no limitation on an institution obtaining samples directly from BEi or other sources. In a public health emergency, the U.S. government seeks to make isolates availab le under a Simple Letter Agreement that does not impose IP restrictions on academics or developers (see attached language). 3. If it can be obt ained from other sources, wh at sources will be perm itt ed? For exa mpl e, th e China or Hong Kong CDC or University of Hong Kong? Assuming appropriate permits and safety controls, there is no limitation on from where samples can be obt ained . However, there may be intellectual property restrictions from some sources and your technology transfer office would need to negotiate if requested directly. 4 . If you are to be th e sole sour ce, w hen would you expect to have a process for considering requests? BEi resources already has a process for sharing in place and is currently sharing the vira l isolate obtained from the first Washington case. NIAID ant icipates t hat other viral isolates will be obtained soon, and BEi is committed to making those available to t he scientif ic community as soon as NIH-001897 possib le. We {NIAID/ USG) do not expect to be the only source, but will likely be one of the main sources for this research resource based on experience w ith Zika. S. If someone wishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? For that, contacting CDC directly would make sense. If you would like us to inquire, we can. For high consequence viruses, use of proper PPEhas been a mitigating factor in quarantine consideration. Please feel free to contact me if you have additional questions. Thanks, Alan Alan Embry, Ph.D. Chief, Respiratory Diseases Branch Division of Microbiology and Infectious Diseases, NIAID, NIH 5601 Fishers Lane, Room 8E31 Rockville, MD 20892 (b)(6) (b)(6) -------- (b)(6) From: Fauci, Anthony {NIH/NIAID) [E] Date: Thursday, February 13, 2020 6:35 PM To: Fried, Linda P. (b)(6J>;Redfield, Robert R. (CDC/OD) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6); Goldman, Lee (b)(6) ,>; Booth, Jane (b)(6)>; Katznelson, Ira I. =======~~~ (b)(6)>; Marston , Hilary {NIH/NIAID) [E] "."--.--.-:--:~==~...:..,_--~= (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] Subject: RE: Institutional request for information (b)(6)> CbH6l>;Embry, Alan CbH6J> Linda: There is a "sample sharing" working group involving NIH and CDC. I have copied both Hilary Marston and Alan Embry from NIAID who are involved in this group and will ask them by this e-mail to respond to items #1 through 4. Regarding returning tr avelers from China {item #5) if in Wuhan {Hubei province) within previous 14 days, they submit to institutional quarantine ; if in non-Hubei province part of China, then they face self-isolation. Hope t hat this is helpful. Best regards, Tony NIH-001898 Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its representatives . From: Fried, Linda P . (b)(6) Date: Thursday, February 13, 2020 12:45 PM To: Redfield , Robert R. (CDC/OD) (b)(6); Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Conrad, Patricia (NIH/NIA ID) [E] -:-"""."""-::===== (b)(6)>; Booth, Jane ======== (b = )=(=;..; =o G = ldman, Lee Katznelson, Ira I. (b)(6)>; (b ;;:; )::c (6) ~ Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to trans fer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDCofficial to import the virus (see attached). Howeve r, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you: 1. Is the CDCor NIH overseeing the distribution of t he live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, w hat sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? 5. If someone wishes to travel to China to work on the live virus, are there any trave l restrictions other than the self isolation/qu arantine already in place (and of course subject to change over t ime)? Thank you ve ry much fo r your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda NIH-001899 Linda P. Fried, M .D., M .P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mai lman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001900 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 03:00:23 +0000 Mansoura, Monique K. Conrad, Patricia (NIH/NIAID) [E);Andrew W Lo;Cassetti, Cristina (NIH/NIAID) [E) RE: A proposed solution to finance COVID-19 vaccines - Introducing MIT's To: Cc: Subject: Professor Andrew Lo Thanks, Monique. Please have Andrew send the proposal to Cristina Cassetti (copied here) and she can then brief me on it. Best, Tony From: Mansoura, Monique K. Date: Thursday, February 13, 2020 10:36 AM To: Fauci, Anthony (NIH/NIAID) [ E] ----- (b)( '> -- (b,... )(=6) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Andrew W Lo (b)(6)> Subject: A proposed solution to finance COVID-19 vaccines - Introducing MIT's Professor Andrew Lo Dr. Fauci, The nation again is fortunate to have your leadership for this latest public health emergency . Thank you for all you are do ing. r know you are extraordinari ly busy, so I'll be brief. I want t0 introduce you to MIT Sloan Professor Andrew Lo, a world leader in healthcare finance who has focused much of his work recently on accelerating bi.omedical innovation via novel financing srrucn1res. :1 have worked with him to explore financial engineering approaches to estab lish more durable public-private partnerships for medical countermeasures. The persistent challenges you articulated at the Aspen Institute event this week resonate loudly with Andrew and me. He has proposal for COVID-19 that he would like to present to you. I defer to him to provide fu1tber information. Respectfully, Monique MON IQUE K. MANSOURA, PH.D., M.B .A . Executive Director, Global Health security and Biotechno logy The MITRE Corpo ration 202 Burl ington Road I Bedford, MA I 01730-1420 Office: (b) (6) (b)(6) The MITRE Corporation is a not-for-profit organization that operates federally funded research and development centers for the United States government. NIH-001901 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:56:17 +0000 Greg Folkers Subject: FW: FYI-- images of SARS-CoV-2now up (b)(6)) Let us make some power point slides from these. Thanks. From: Billet, Courtney (NIH/NIAID) [E) Se nt: Thursday, February 13, 2020 1:22 PM -------- (b) ~ > To: NIAID OD AM Subject: FYI -- images of SARS-CoV-2 now up https://www.niaid .nih .gov/news-events/nove1-coronavirus-s arscov2-images https://www.flickr .com/photos/niaid/albums/721 57712 9 14621487 NIH-001902 Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:42:53 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b) ( ·) FW: PBS'SFIRING LINE REQUEST// DR. ANTHONY S. FAUCI From: Date: To: Cc: Subject: Patty: Let us discuss. Greg: Are they a big dea l? From: Melanie Starling Se nt : Thursday, February 13, 2020 6:39 PM To: NIAID NEWS (NIH/N IAID) ; Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: PBS'SFIRING LINE REQUES T // DR. ANTHONY S. FAUCI Import ance: High Good Evening, Please see below for Dr. Anthony S. Fauci for PBS'S FIRING LINE WfTH MARGARET HOOVER . Due to a last minute cancellation, we are crashing on a deadline and need to know if he is able to jo in us ASAP. I look forward to hear ing your thoughts and all best , Melanie Melan ie Starling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@thedocumen t arygroup .com ___.------- -- Fl RI n G LlnE W ith MA RGARET Good Evening, NIH-001906 HOOVER This is Melanie Starling writing on behalf of PBS'SFIRING LINE WITH MARGARET HOOVER. FIRING LINE is the rare program in the political landscape that seeks a rigorous and earnest exchange of ideas, with the luxury to let the conversation breathe. Margaret has brought back the spirit of this venerated show, which aired from 1966 to 1999, that is lacking in today's polarized cable news ecosystem - at a time when we need it more than ever. One guest. 30 minutes. Airing to a thoughtful and engaged PBS audience. We would be honored to have Dr. Anthony S. Fauci join Firing Linefor an interview. Dr. Fauci has dedicated his career to understanding, preventing, and protecting people across the globe from infectious diseases, which is why we would be so honored to share our stage with him at this time. As the coronavirus continues to spread, we are interested in better understanding the deadly virus the world is racing to contain. Equally, we are interested in highlighting any other public health issues or policies close to Dr. Fauci's heart. Most importantly, with our program, we have the luxury of time-where we can truly delve into these issues in a substantive, nuanced manner that is missing in much of today's 24-hour news cycle. THE DETAILSFORTAPING TAPE DATE: TARGETING FEBRUARY19TH - EVENING TAPING IS PREFERED TAPE TIME: 45 MINUTES LOCATION: NYC (WNET STUDIOS NEAR LINCOLN CENTER) TRAVEL, HAIR, & MAKE-UP IS PROVIDED ON REQUEST. f lRING LINE is carr ied nationwide on PBSwith 99% market pick-up, and is suggested programming for PBS's8:30 PM ET on Friday nights with multiple airings through the week. On Twitter, we have a growing 2.9M+ monthly impressions. Equally, as you know, PBSremains a coveted home for intellectual, elevated programming- and stands out as a top 5 outlet to reach persuadable voters. HIGHLIGHT REEL FIRING LINE is produced by the Oscar-nominated Tom Yellin at The Documentary Group. Please reach out to me if there is any interest . We will bend over backwards to get it done. Thank you in advance for your consideration, and please feel free to reach out to me 24/7 with questions or concerns. All the best, NIH-001907 Melanie Melanie Sta rling Firing Line with Margaret Hoover Cell: (b)(6) Email: melanie@ t hedocumentarygroup.com ABOUT FIRING LINE WITH MARGARET HOOVER Firing Line with Margaret Hoover is a refreshing reprisal of William F. Buckley's icon ic PBS program, a smart, civil and engaging contest of ideas. The series maintains the character of the original, providing a platform that is diligent in its commitment to civility and the rigorous exchange of opinion. Firing Line with Margaret Hoover comes at a time when mean ingfu l discourse is needed more than ever. Interviews and debates will highlight leading lights from the left and right, complemented by archiva l footage from the original Firing Line to rem ind viewers of longstanding conservat ive and libera l arguments, where they've been disproved or reinforced over time. It is an opportunity to engage in the debate about the America tha t we want to create fo r the 21st centu ry - and summon Americans of every politica l persuasion to a rigorous examination of the choices we must make together in the challenging years ahead . Showrunner is Emmy, Dupont and Murrow-winning producer Alyssa Litoff. ABOUT MARGARET HOOVER Margaret Hoover is an American political commentator . In addition, she is also an author, fem inist, and gay rights activist. Current ly, she wo rks as a polit ical commentator for CNN. HIGHLIGHT S ON FIRING LINE WITH MARGARET HOOVER Speaker Paul Ryan, Sen. Ben Sasse (R-NE), Gov. Chris Christie, Gov. Mitch Daniels, Gov. John Kasich, Gov. Scott Wa lker, Rep. Alexandria Ocasio-Cortez (D-NY), Rep. Eric Swalwell (DCA), Stacey Abrams, Donna Brazile. Gretchen Carlson. Caitlyn Jenner. Christine Lagarde, Peter Navarro, Oliver North, Andrew McCabe, Tom Steyer, H.R. McMaster, Rep. Tulsi Gabbard, Ann Coulter, Tony Blair, Jose Andres, Rep. Liz Cheney (R-WY), Rep. Jim Clyburn (D-SC), Rep. Pramila Jayapa l (D-WA), Sen. Ted Cruz (R-TX), Gen. Jim Matt is, Condoleezza Rice, Andrew Yang, Michael Bloomberg, Michael Moore, Paul Krugman, Amb. Nikki Haley, Adam Schiff (D-CA) Melanie Starling PBS's Firing Line with Margaret Hoover Cell: Cb)(6) Email: melanie@thedocumentaryqroup.com -FIRlnG ----LlnE NIH-001908 From: Date: Fauci, Anthony (NIH/NIAID) [E) Fri, 14 Feb 2020 02:36:46 +0000 To: ncalio@airlines.org Cc: Conrad, Patricia (NIH/NIAID) [E);Redfield, Robert R. (CDC/0D);Cetron, Marty (C0C/0010/NCEZID/DGMQ) Subject: FW: Coronavirus Task Force Attachments: Fauci A4A Letter to Coronavirus Task Force .pdf Nick: Many thanks for sending this. The CDC would be very interested in your willingness to move in the d irection of having complete contact information on passengers available to them. I am copying CDC Directo r Bob Redfield and his CDC colleague Marty Cetron on this e- mai l. I am sure that one o f them will contact you about this issue. Best regards, Tony From: Calio, Nicholas Date: Thursday, February 13, 2020 8:18 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=Subject: Coronavirus Task Force (b):--: (6) => Dear Dr. Fauci , Please see the attached letter. Thank you, Nick Calio NIH-001909 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 14 Feb 2020 02:09:44 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitation: 388393 Santos (Coronavirus Preparedness Workshop) To: Subject: Tell them that I turned down the same invitation major event and he should turn it down also. From: Conrad, Patricia (NIH/NIAID) [E] Date: Thursday, February 13, 2020 8:21 AM ---------- It is not a (b)(6) ------~~ ,..;.::=======:,;,~ Cc: Folkers, Greg (NIH/NIAID) [El To: Fauci, Anthony (NIH/NIAID) [El --------- Subject: FW: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) Please see below . You were invited to this - it was discussed in our daily meet ing and we decided to decline it for you. we d id decline it. would you recommend the same as they are now asking Dr Collins. Pis advise. Patricia L. Conrad Public Hea lth Analyst and Spec ial Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachme nts is confidential and may contain sensitive info rmation. It should not be used by anyone who is not the orig inal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Aller gy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one or its representatives. From: Harris, Kara (NIH/NIAID) [El -------Date: Wed nesday, February 12, 2020 4:18 PM To: Conrad, Patricia (NIH/NIA ID) [E)-------~~ (b)(6)> Cc: Billet , Courtney (NIH/N IAID) [E)· .=.====~ (b ~) ~(6)~ >-; (b)(6)> ~ Haskins, Me linda (NIH/NIAID) [E] (b)(6) Subject: Invitation : 388393 Santos (Coronavirus Preparedness Workshop) NIH-001910 Hi, Patty Exec Sec would like Dr. Fauci's opinion on whether Dr. Collins should accept the attached invitation to speak at an upcoming Coronavirus Preparedness Summit & Workshop being held this June in Washington, DC. The conference is being organized by Syllabusx, a group of "international specialists in public health and emergency planning events and disaster recovery conferences ." Given the nature of the conference topics, do you concur with recommending Dr. Collins decline the invitation and refer to CDC? Thanks for your input. Kara NIH-001911 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 23:22:27 +0000 Alison Galvani Conrad, Patricia (NIH/NIAID) [E] RE: Lancet special issue proposal Alison: Thanks for the note . I really appreciate your kind invitation, but unfortunately, I will have to decline. My plate is already overflowing and I just cannot take on any additional editorial responsibilities . In addition, I am swamped with coronavirus "stuff" that is not going to end soon. I hope that you understand . Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alison Galvani (b) (6) Date: Wednesday, February 12, 2020 2:28 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Lancet special issue proposal ------ ..-.-,= Cb H > Hi Tony, I hope you are well. (b) (4) Thank you so much for your consideration. NIH-001912 Warmest regards, Alison Alison Galvani, PhD Director, Yale Center for Infectious Disease Modeling and Analysis (CIDMA) Burnett and Stender Families Professor of Epidemiology Yale School of Public Health Yale School of Medicine New Haven, CT 06520 (b)(6) htt p://c idma .yale .edu/ NIH-0019 13 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Thu, 13 Feb 2020 23:10:07 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Personal connection To: Subject: Please set this up (5 minutes) for Monday. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ---------------=-,-:-= From: Conrad, Patricia (NIH/NIAID) [El Date: Wednesday, February 12, 2020 8:58 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: FW: Personal connection -------- (b)(6)] (b)(6) This guy called last night and seemed to know you - let me know if and where you want me to direct him. Or maybe do a call with you on a quieter day - Monday on Pres day holiday? Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: NIH-0019 14 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone w ho is not the original intended recipient. II you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIA ID by one of its representatives . From: Banner, Jon {PEP} (b)(6)> Se nt: Tuesday, February 11, 2020 9:44 PM To: (b)(6) Conrad, Patr icia (NIH/NIAID) [E] Subject: Personal connection ----------- (b)(6) Dear Dr. Fauci, Jon Banner here. You may remember me from my days at ABC News, where I was Executive Producer of World News Tonight with Peter Jennings, Charlie Gibson, and Diane Sawyer . I was also Executive Producer of This Week with George Stephanopoulos and early on I was George Strait 's producer. Back then, you were the most engaging, eloquent guests on the subject of HIV/AIDS and other life and death issues of our time, and your input was of enormous value to our viewers and the general public. Today, I am President of the PepsiCo Foundation and EVP of Global Communications for the company . I was hoping you could help us identify an expert to provide similar insight and analysis for our company as we deal with the impact of the Wuhan coronavirus . While we would of course welcome your counsel, I recognize that you have a full plate of critica l responsibilit ies with NIH and don' t want t o take up too much of your time. If you have a few minutes for a quick call, I'd love to get your take and catch up. If not, I would deeply appreciate it if you could connect me with another expert over email. Thanks very much, and hope you are doing well! Warm regards, Jon NIH-001915 From: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:47:23 +0000 Eisinger, Robert (NIH/NIAID) [E] FW: Institutional request for information Cll 2020 CDC import permit .pdf Date: To: Subject: Attachment s: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fried, Linda P. Date: Thursday, February 13, 2020 12:45 PM To: Redfield, Robert R. (CDC/OD) (b)(6) (b)(6) Fauci, Anthony (NIH/NIAID) [E] (b)(6) >; Goldman, Lee ----======~~~ Cb _H_ ; Katznelson, Ira I. Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)(6); Booth, Jane ________ ======== (b)(6) (b ~)~(6) ;;-- Subject: Institutional request for information Dear Ors. Redfield and Fauci, I am writing on behalf of Columbia University, w hich has received a request from Dr. Ian Lipkin to transfer live novel coronav irus from Hong Kong to his BSL3facility at the Univers ity. As we evaluate his request , we note that he has approval from a CDC official to import the virus (see attached) . However, as we consider the risks and benefits of Dr. Lipkin's proposal, we ask the two of you : 1. Is the CDCor NIH overseeing the distribution of the live virus in the U.S.? 2. Will you be the sole source of distribution in the U.S., or will institutions be permitted to obtain it directly from other sources? 3. If it can be obtained from other sources, what sources will be permitted? For example, the China or Hong Kong CDCor University of Hong Kong? 4. If you are to be the sole source, when wou ld you expect to have a process for considering requests? NIH-0019 16 5. If someone w ishes to travel to China to work on the live virus, are there any travel restrictions other than the self isolation/quarantine already in place (and of course subject to change over time)? Thank you very much for your help with these important questions as we all try to do our best to contribute solutions to this health crisis. With best regards, Linda Linda P. Fried, M.D., M.P.H. Dean and Delamar Professor of Public Health Professor of Epidemiology Mailman School of Public Health Professor of Medicine, Vagelos College of Physicians and Surgeons Senior Vice President, Columbia University Irving Medical Center Columbia University NIH-001917 Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:44:12 +0000 To: Stoffels, Paul [JJCUS] Cc: Riccobene, Kim [JJCUS];VanHoof, Johan [JRDBE);Conrad, Patr icia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [(] ;Eisinger, Robert (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Mascola, John (NIH/VRC) [E];Erbelding, Emily (NIH/NIAID) [E] Subject: RE:COVID-19 vacc ine development From: Date: Paul: Thanks for the note. I will have Patty Conrad {copied here) try to work something out for Feb.21 st . My schedule is at the mercy of t he White House and the Congress and so I cannot guarantee anything right now. Best Regards, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and n ot expre ssly made on behalf of the NIAID by one of its representatives . ------13, From: Stoffels, Paul [JJCUS] Date: Thursday, February 2020 9:42 AM To: Fauci, Anthony (NIH/NIAID) [E) ----Cc: Riccobene, Kim [JJCUS) Subject: COVID-19 vaccine development -------- (b)(6)> --:a (b=H=6)> (b)(6); -------- Van Hoof, Johan [JRDBE) (b)(6)> Dear Tony, Four weeks ago our team kicked of the experimental work on the development of a COVID-19 - vaccine. (b) (4) NIH-001918 (b) (4) If you have time for a meeting on the 21st in the afternoon or a call in the course of the next 10 days, I would much very appreciate . Feel free to call me or have you assistant connect with my assistant Kim Riccobene to set up a call. I will be in Europe till the 19th . Best regards, Paul Paul Stoffels, MD Vice Chairman & CSO Johnson & Johnson (b)(6) (Mobi le Europe) (Office US) NIH-001919 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Thu, 13 Feb 2020 03:16:08 +0000 Barasch, Kimberly (NIH/NIAID) [C) FW: Run of show- 2/13, 9-l0am Wh ite House Roundtable on COVID-19 Make sure that this is in my folder. (b)(6}> From: Selgrade, Sara (NIH/NIA ID) [El Date: Wed nesday, February 12, 2020 3:16 PM To: Fauci, Anthony {NIH/NIAID) [El-----~~ (b)(6) Cc: NIAID OCGR Leg ; Conrad, Patr icia (NIH/NIAID) [El (b)(6)Barasch, Kimberly (NIH/NIAID ) [C] (b)(6) Billet, -------- Courtney (NIH/N IAID) [E] (b)(6) Subject: Run of show - 2/13 , 9-lOam White House Roundtable on COVID-19 Dr. Fauci, Please see below for information we have received from HHS thus far regarding tomorrow's briefing on coronavirus at the White House. Patty has subm itted your inf onnation via the WAYES link for the event. We are checking with HHS ASL to make sure your clearance has been proce ssed. We will share any additional information as we receive it. Please let me know if you have any questions. Thanks , Sara White Hou se Congressional Roundtable on Coronavirus Date: Thursday, February 13 Time: 9:00 - I 0:00 a.m. Location: Roosevelt Room Run of show: • Acting Chief of Staff Mulvaney will open the proceedings and briefly frame all that we are doing and why we have asked the Members to assemble (to gain their insight and to seek their wisdom). NIH-001923 • Anne Schuchat will give a brief overview of current status and material issues . • Anthony Fauci will give a brief explanation of our understanding of the virus and development of countermeasures. • Brig Gen. Paul Friedrichs of DoD will provide a brief status report on force protection. • Acting Chief of Staff Mulvaney will open the floor for questions and moderate the proceedin gs - possible that White House legislative affairs will stand in here (Eric Ueland or Mike McKenna). Expected participant s: Members (confirmed RSVPs thus far) Senator James Risch Leader McCarthy Rep. Kay Granger Rep. Greg Walden Rep. Nita Lowey Briefers DHS-Alex Zemek CDC- Dr. Anne Schuchat NIAID-Dr. Tony Fauci ASPR- Dr . Bob Kadlec FDA-Dr. Steve Hahn DHS - Ken Cuccinelli NSC - Anthony Riggiero NSC - Matt Pottinger State - Stephen Biegun (tentative) DOD - Brig Gen. Paul Friedrichs NIH-001924 From: Date: (b)(6) Wed, 12 Feb 2020 11:02:30 -0500 To: Subject: John Lauerman Re: Interview I tried calling but the call would not go through On Feb 12, 2020 , at 6: 15 AM , John Lauerman (BLOOMB ERG/ NEWSROOM:) wro te: Hi Dr. Fau c i : I saw t hat you spo ke about t he lac k of major drugmakers stepping up to make coron av irus vaccine , a n d my colleague James Paton is working on a story about that issue . J ames ' s story has to do with a bi osecurity initia t ive related to these types of t hreats at GSK tha t was started in 2016 and quickly pu t on t he bac k bu r ner . I do n 't know whe t h e r you ' d want t o commen t on the company or its activities i tse lf , bu t wou ld b e he l pfu l if you could talk about t he im p ortance of ge ttin g big drugmakers involve d in helping t o fill t he need f or new vaccin es . I ' m in Geneva ri gh t now at the WHO coronavirus science foru m, b ut ho pe we can t a l k for a mi nut e or t wo . Bes t way to r each me is via Whatsapp , where my number i s (b)(6). Ple ase let me know if/when you ' re free . Thanks and regards , JL From: John La uerman (BLOOMBERG/ NEWSROOM : ) At : 02/07/20 To: (b)(6) Sub j ect : RE : Int erv i ew Und er stood . Hope you ge t a chanc e to r es t 15 :53 : 34 From: a f auci@niaid . nih . g ov At : 02/07/20 15 : 51 : 39 To: J ohn Laue r man (BLOOMBERG / NEWSROOM : ) Sub jec t : RE : Interview Sorry John. I am totally tied up right now and besides, I am completely hoarse and can barely speak. Let us try some other time. Anthony S. Fauci , MD Director Nationa l Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) NIH-001925 FAX : (301) 496-4409 E-mail: Cb ) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this email in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infe ctious Diseases (N IAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: John Lauerman (BLOOMBERG/ NEWSROOM :) Date: Monday , February 3, 2020 8 :18 AM To: Fauci, Anthony (NIH/NiAiD) [E] (b)(6) Subje ct: Interview ------~~ Hi Dr . Fauci : How are you? I ' m wri t ing t o see whether we can talk again fo r a few minutes. We' r e worki n g on a b i gg i s h p iece abou t t he l arger b i o-secur i t y i ssue wor l dwi de a n d wh a t t he coronavi r u s outbreak tells u s abo u t it . What can we do abou t t he weakes t lin ks in d i sease co n t ro l in p oore r n a t ion s in Af r ic a , Asia a n d e l sew here? The WHO today bro ug ht up the impo r tance of access to health care along with spending on p ub li c h ea l t h, a n d c l ear l y t hi s i s a n issue in poo r co un ties . Is it also important in infectio us disease in the US and if so, is it ad e qua t ely recognized? Compa nie s a nd research centers have made h ug e strides in q u ick development of vaccines and dr ug s ; what can take i t t o t he nex t level? Is t he r e a ny t hing t ha t co ul d be done to attract more companies to this field? What kind of n e w t e chnologi e s can help u s t rack ne w v i ruses in t he commu ni t y? I ' ve bee n t a l k in g wi t h peop le using h a nd hel d n a no por e seq u ence r s to track coronavi r u s and Ebola ; what el se i s ou t t here? Do we nee d t o do a b e tt er job of t racking t he move men t of peop le a n d goods? Also glad to get any other observations . Please c a l l t oday or t omorrow mornin g at ~ o r le t me k no w when a nd a t wh a t ( number to call you . Thanks and re g ards , look forward t o he ar in g from you , JL NIH-001926 John Lauerman, Bloomberg News 3 Queen Victoria Street, London , UK tel. +44 (0) 2035 251028 cell http ://www .bloombe rg.com http://www .bloom berg .com /prog nos is --------=--=-:= --------- NIH-001927 Cb)(6) From: Date: (b)(6) Wed, 12 Feb 2020 10 :24:06 -0500 To: Daniel Lucey Subject: Re: Update IDSA Science Speaks post today# 10: PPEmass production and POlyclonal/mAbs Rx PReP and PEP Thanks dan On Feb 12, 2020, at 9:34 AM, Daniel Lucey --------- Cb)(6) >wrote: Bob K., Tony and Bob (Redfield), Given the news of health care personnel in Wuhan and Hubei being infected, and acute shortage of PPE for COVID-19, I posted these Q&A s on the ID Society America "Science Speaks" website as the 10th in a series of my updates since January 6th. The final Question asks and answers that mass production of COVID-19 PPE should occur now. Dan Hong Kong Feb. 12, 2020 bttps ://sciencespeaksblog.org/2020/02/ l 2/immune-survivors-of-covid-19-protectiveantibody-for-treatmen t-and -prophylax is/ NIH-001928 Fauci, Anthony (NIH/NIAID) [E) Wed, 12 Feb 2020 15:23:15 +0000 To: Folkers, Greg (NIH/NIAID) [E) Cc: Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [C] !';ubject: Re: Business Counci l - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attach ment s: image003.jpg, image004.jpg, imageOOS.jpg From: Date: Okay. Go with it On Feb 12, 2020, at 9 :38 AM , Folkers, Greg (NIH/NIAID) [E] (b)(6) wrote: Will add I would vote fo r: no slidesI would send these three papers (all on director's page) - CoV, Ebola, Ending HIV Foreign Policy From: Conrad, Patricia (NIH/NIAJD) [E) Date: Wednesday, February 12, 2020 9:11 AM To: Folkers, Greg (NIH/NIA ID) [El Cc: Fauci, Ant hony (NIH/NIAID) [El _______ --------- (b)(6) ~======'~~Cb> _<_.; Barasch, Kimber ly (NIH/NIAID) [CJ (b)(6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Kim - pis add all t o th e f olde r t hx NIH-001929 G - this needs to be added to matrix. IT was a "fires ide chat" that we thought would not include slides but see below -they are ok with a few slides Will need to discuss things to send and topics given the "theme" Patricia L. Con rad Public Health Analyst and Special Assistant to the Director Nation al Inst itute of Allergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Mary land 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information. It shou ld not be used by anyone who is not the original intende d recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. Nationa l Institute of A llergy and Infect ious Diseases (NIAID ) shall not accept liabil ity for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives. From: Marlene Colucci Date: Tuesday, February 11, 2020 6:29 PM To: Conrad, Patricia (NIH/NIAID) [El --------=(bs)( =6) Cc: Adrienne Ball ; Gillian Auger Subject: Re: Business Council - Invitation to speak at th e February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. Patty, I wanted to check back with you and Dr. Fauci on a few things in advance of his fireside chat with David Rubenstein on Friday, February 21. • Are there any art icles tha t Dr. Fauci thinks would be useful to send out to our CEOs in advance of the discussion (it may be something related to the Coronavirus or something that looks at the future of health and what CEOsshould be thinking about in the next decade? NIH-001930 • The theme for our upcoming meeting is "The Next Decade - Major trends in technology, geopolitics, politics, economy and health" . I have attached a copy of our Draft CONFIDENTIALand list of attendees for Dr. Fauci's reference . • During his discussion with David Rubenstein, are there any slides he would like to use for reference? We do not use a lot of these but thought there might be slides that wou ld aid in his discussion? Just let us know. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSI1 TESS l0L \.C.L.. T: 202-298-7650 C: (b)(6) F : 202-785-0296 On Feb 5, 2020, at 9:19 AM, Ma rlene Colucci wrote: Thank you Patty for checking. As soon as I can find out whether Dr. Collins wi ll also be a part of the discussion I will work on setting up t hat call. Ive been pressing their office so fingers crossed! Marlene Marlene Colucci EXECUTIVE DIRECTOR "I ~ T : 202-298-7650 BUSINESS COL.:\JCIL C: (b)( 6) F: 202-785-0296 NIH-001931 On Feb 5, 2020, at 9:01 AM, Conrad, Patricia (NIH/N IAID) [E] (b)( wrote: ---------- Good morni ng: Dr. Fauci w ill not be abl e t o att end th e di nne r th e night befor e but want ed me t o thank you f or t hink ing of him. Best , -patt y From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIA ID) [E] -----.-.. (b.., H=6J Cc: Conrad, Patricia (NIH/NIAID) [E] CbH6J ; (b)( ; MaryPat David Rubenstein (b)(6) Decker Subject: Business Council - Invitat ion to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington , D.C. ------------ Dear Dr. Fauci, On behalf of our co-chairs for the winte r meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we wou ld like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal invitation attached as well as list of CEO members). We would like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We wil l cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. NIH-001932 As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH (Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate wit h us again. Warmest regards, Marlene Marlene Colucci EXECUT IVE DIRECTOR ·11• ~ ~ T : 202 -298-7650 C: (b)(6) F : 202- 785-0296 BUSINESS COL '!CTL i:@H@Vitw\ 304.257 c.t.at.anso Al!ll1etric 2109 Vl~wpoint January23. 2020 CoronavirusInfections-More Than Justthe CommonCold e,,11.. w, P""""'-1o10• • ....,.,0 """"°"·"°'..,,,.,,.,,,llooy~ f.1W.l.fl>1 ,....,,.,,...,.f.i.,I """'-l~1t!o<,.,.,.., /Ml,\. P\.ll»ihNl<>nl .. S,,,--, l).10/0, cir, IQ1001/1,oN.JQX)flm NIH-001933 AI\OUl'!fNI On the Front Lines of the Trump Administration's Ebola Response The IJnilal S\.11CS l\.'15mounlOOn wide ~ (t,JlOO.SC\0 the~ e~, Volu1TW' 69, b,ue 11, LS De<.e,nbt-r20 tt. P•g~ 1n :>-2>l1, .,UJ>~/irtn, MY ICJIC"~ilffd/c ,,,,.lH ClinicoJ f11k<.~ PubUJhe d: 24Octobet2019 Arlk le hlstory • NIH-001934 1/§·MU Vlew. 304.2S7 C.t•t.oclMO Alun<,tric 2t09 Viewpoint January 23, 2020 Coronavirus Infections-More Common Cold c..uiann.tl'Me5,MD 1,......,D -,MO, MPl◄1;Andlo,,y'd.Ml.W >A11thofAff11,,f1'0f1'\ I M-.1l"~f "'-'" ~- NIH-001935 Than Just the -13.1010. ~ •tton dol10100t/!,,m,ll0l001'>1 ARGUNCN T On the Front Lines of the Trump Administration's Ebola Response The t:nitcdSlatesti,., mounteda wide r.mgiQgrcspoo.dl)'outbrc-'11<. osonly~ can. NIH-001936 Ending the Human Immunodeficiency Virus Pandemic: Optimizing the Prevention and Treatment Toolkit s o NIH-001937 C/inicollnf«IX>U1D,seo=, Volmnf' 69, Issue 12, IS Oecembe00l9 , P•ges 2212- 2117, I tlJ)';//dol.org/ l O.lO'J]/cid 1<1t' :IS Pubtiffled: 24 Oelobet 2019 Artkle history • From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [El Wed, 12 Feb 2020 12:04:55 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: epiqar for Coronavirus assistance Please handle. Thanks. From: Daniel Goldberg Date: Tuesday, February 11, 2020 11:18 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: epiqar for Coronavirus assistance Dr. Fauci, I wanted to reach out to see if epiqar (https://ep iqar .com/) can help your efforts with the Coronavirus- we are the only system in the world built for remote surgical help & interactive emergency surgeon support over the web browser. epiqar has created the most advanced surgical video collaboration technology, allowing surgeons to consult and train remotely on a low-cost and easy-to-use online surgical collaboration platform and Cloud-archiving system built for the operating room. With the outbreak of Coronavirus, this has become more vital as surgeon mobility and access to critical surgical spaces in need of more help are severely limited, and specialists will not risk entering spreading viral hot zones. Patient care isn't just a concern with the virus itself, but with the host of medical issues facing patients that will no longer be treated by local specialists easily, and facing caregivers: surgeon involvement from around the world is needed urgently. Although epiqar is an American company, our rollout in recent months has been in France, making selected French institutions the most prepared in the world for remote video care. We obviously weren't anticipating the Coronavirus and now we're dedicated to delivering our technology to where the world needs it asap. epiqar 's parent company ENGAUGE (https://eng.us/ ) is a state-of-the-art online healthcare company for surgeon training and has served clients such as Johnson & Johnson , Intuitive Surgical, and many other of the world largest & smallest medical device companies. ENGAUGE has helped surgeons all over the world have access to secure online training that has improved their understanding of the innovations in robotics and many of the latest surgical techniques and medical devices for best patient care. I've linked a whitepaper below with details of the system's use. Please let me know if you would like to speak further and/or need anything additional. Thanks, NIH-001938 Danny www .epigar. com epiqa r I whitepaper Daniel Goldberg CEO ENGAUGE www .eng.us www .epiqar.com The world 's first low-cost telementoring, surgeon training and instant Cloud-archiving Platform us 888.615.7874 EUROPE44 2031399059 NIH-001939 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00 :16:12 +0000 Conrad, Patricia (NIH/NIAID) [El FW: AMA news interview request: What to tell your patients about COVID-19 Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sara Berg Date: Tuesday, February 11, 2020 4:55 PM To: Fauci, Anthony (NIH/NIAID) [El (b)((;)> Subject: AMA news inte rv iew request: What to tell your patients about COVID-19 -------=-=-c= Dear Dr. Fauci, My name is Sara Berg and I am a senior wr iter for the AMA . I am reach ing out to you today because you have shared a lot of great information about COVID-19 with the JAMA networ k. I know you are very busy, but I was wondering if you wou ld be available tomorrow or Thursday for a quick phone inte rview about what to tell patients who suspect they have COVID-19? This would be an AMA news art icle for physicians about what to tell patients. The CDC has a list of preventive steps : https ://www .cdc .gov/coronavirus/2019-nc ov/hcp/gu idance -prevent -spread .html . This would be what phys icians should tell patients who suspect they have COVID-19. One tip might be "Call before you come in." Do you think this is something you would be available to participate in? I look forward to hearing from you. Thank you , NIH-001940 AMA~ Sara Berg Senior Communications Specialist Sara.Berg@ama-assn.org Office: (312) 464-4104 00000 AMA membership: Join or renew today! MEMBERSHIP MOVES MEDICINE ... NIH-001941 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 12 Feb 2020 00:13:52 +0000 Cassetti, Cristi na (NIH/NIAID) [E] FW: 2019 nCoV brief fyi (2+ pages) Brief 2019 nCoV host Se status.doc Date: To: Subject: Attachments : Please handle. Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Michalann Harthill Date: Tuesday, February 11, 2020 3:41 PM To: Fauci, Anthony (NIH/NIAID) [E) Cc: Morens, David (NIH/NIAID) [E] Subject: 2019 nCoV brief fyi {2+ pages) (b)(6) -------=-:--:= (b)(6) :.::========-=.,~ ---------(b)(6) Dear Dr. Fauci, Please find attached, FYI, my synopsis Emergence of a novel coronavirus (2019-nCoV), Wuhan, Hubei Province, China: human host selenium-deficient status as a possible "driving" etiological determinant. (2 1/4 pages, ~70 refs, no graphics) Best regards, Michal Harthill GHI, Inc., Frederick, MD (b)(6) NIH-001942 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Wed, 12 Feb 2020 00:05:00 +0000 To: Subject: Attachment s: (b)(6) FW: take a look at figure 3 of the new nejm paper nejmoa2001316.pdf See Greg/ David comm ent below . Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail. (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Tuesday, February 11, 2020 2:50 PM To: NIAID OD AM Subject: take a look at figure 3 of the new nejm paper --------- (b) (5) Thanks david NIH-001943 (b) (5l From: Folkers, Greg {NIH/N IAID) [E) Date: Tuesday, February 11, 2020 10 :04 AM To: NIAID OD AM Subject: this is t he nej m paper discussed this a.m . That asf is op ining on Disclaimer: Any third-party material in this email bas been shared for internal use under fair use provi sions of U.S. copyright law, without further verification of its accuracy/veracity . 1t does not necessarily repre sent my views nor tho se of NIAJD , NIH, HHS, or the U.S. gove rnment. NIH-001944 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Tue, 11 Feb 2020 23:58:00 +0000 NIAIDODAM FW: Keynote Invitation: 3/20 CSISCoronavirus Public Event This coul d be good since it is local. Let us discuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Stephen Morrison Date: Tuesday, February 11, 2020 1:20 PM --------=-,,-:-= --------- To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Anna Carroll ; Samantha Stroman ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Keynote Invitat ion: 3/20 CSIS Coronavirus Public Event Dear Dr. Fauci, I hope this note finds you well. It is my pleasure to invite you to be the opening keynote speaker at a CSIS public event on coronavirus on Friday, March 20, 1:30-3:30 pm at CSIS (1616 Rhode Island Avenue NW) . The event will focus on the science, economics, and politics of the coronavirus and will feat ure experts on Chinese and international politics and economics, as well as public health . We would ask you to speak approximately 1:30-Z:OOpm. Your keynote would be followed by a panel discussion and a closing address, and we invite you to stay for as much of the event as you are able . Please find the full draft agenda and speakers for the event below for your reference . We would be honored to have you participate in this important and timely event. Thank you for your conside rat ion, and please let us know if you would like to discuss further or if we can answer any questions. We loo k forward to hearing from you . Best, Steve NIH-001945 Draft Agenda: 1:30-2 :00 pm - Opening Keynote Dr. Anthony Fauci, NIAID Introduced by Steve Morrison, CSISGlobal Health Policy Center 2:00 -2:50 pm - Panel Discussion {The economics/business] Joyce Chang, JP Morgan (confirmed) {The politics] Jude Blanchette, CSISFreeman Chair in China Studies (confirmed) [The foreign politics] Melanie Hart, Center for American Progress (to be invited), or Bonnie Glaser, CSISChina Power Project {The public health] Steve Morrison, CSISGlobal Health Policy Center (confirmed) Moderato r : Scott Kennedy, CSISTrustee Chair in Chinese Business and Economics 2:50-3 :30 pm - Newsmaker Speech Matt Pottinger, NSC(to be invited) Moderato r and Follow-up Interview: Bonnie Glaser, CSISChina Power Project J. Stephen Morrison Senior Vice President & Direct or, Global Health Policy Center Center for Strategic and International Studies (CSIS) 1616 Rhode Island Ave NW Washington D.C. 20036 (202) 775 -3276 NIH-001946 From: Date: To: Subject: Fauci, Anthony (NIH/ NIAIO) [El Tue, 11 Feb 2020 23:45: 51 +0000 Lerner, Andrea (NIH/NI AID) [El FW: Pharmacist's/ Prescriber 's Lett er Review Request - Coron av irus Please t ake a look at thi s and respo nd for me. Tha nks, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectiou s Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jennife r Nieman Se nt : Tuesday, Februa ry 11, 2020 11:00 AM To: Fauci, Anth ony (NIH/ NIAID) [E] ------- --------- =---c-c= (b)( 6) Subject: Pharm acist's/ Prescri ber's Lette r Revi ew Request - Coron aviru s Dear Dr. Fauci, In the March 2020 issues of Pharmacist 's Letter and Pre scr iber's Letter, we plan to write about coronavirus. Pharmacist 's and Prescriber 's Letter is an independent advisory service for pharmacists and physicians. We are not affiliated with any other group , organization, or company. We are 100% subscriber supported. Our focus is providing practica l, unbiased advice to subsc ribers on issues related to drug therapy . Each month we turn to experts like you to help us pin down the most relevant and important informatio n to share with our reade rs. Our newsletter is well known for being concise and accurate. You will notice the excerpt we are sending you is relatively short . NIH-001947 We would be most appreciative if you would take j ust a few moments to review what we have written for accuracy and content. Please share any comments or suggestions for changes you may have on the article . In order to incorporate your comments into the final Letter, please let me hear from you by Monday , Feb . 17th . I can be reached by email jnieman@P Letter.com or phone (402) 660-4715. I look forward to your reply. INFECTION CONTROL The ongoing ou tb reak of t he novel quest i o n s about h ow t o li mi t t he spread infec t ion s . Managing this situation MERS ... s in ce coro n av i ruses is are coronavirus wi ll of r e sp i ratory similar to outbreaks spread by resp i ratory Pu t t he risk in perspect i ve t o calm worr ie d patients . .. since it doesn ' t come close to the risk raise of SARS and secret i ons . of influenza . For example, over 35 MILLIO N U. S . patients got the flu last seaso n . . . wi t h about 500 ,000 ho sp i ta li za t i o n s a nd 34 ,000 deaths . Emphasize stress yet . getting a flu vaccine each year . And us e this coronavirus outbrea k as an opportunity to infection control ... since there ' s no treatment o r vaccine Reinforce p roper han d h yg iene . Educate t ha t h a n dwas hing wi t h soap a n d water i s t he best way t o g e t r i d of germs . Advise was hin g for 20 seco nds ... about t he t ime i t tak es t o s in g t he ABC so n g . Or recommend using a han d sani t izer alcohol if handwashing isn ' t practical . this much . wi t h a t leas t 60% Many prod u cts contain But tell patients to be wary of efficacy claims . For e xamp l e, h a n d sa ni t i zers are s ho wn t o k ill en v e l oped v i ruses Coronavir u ses are enveloped viruses ... b u t they aren ' t specifically st u died . NIH-001948 . Tell mouth . patients to avoid Clear up confusion for SICK patients ... to t he a ir . touching their about mas ks. help keep their eyes, nose , and Emphasize that mas ks are germs from g ettin g into But d i scourage surgica l masks for mos t patients withOU T symp t oms ... t here ' s no e v i d ence t he y he l p . The y ' r e t oo l oo s e t o l imi t inh a l ing germs ... a nd v i rus e s ca n a l so ge t in t h ro ugh th e e y es . I f pat ien ts ask about req u ire fittin g and training healthcare workers . N95 res p ira t ors , t e ll t hem t hese before us e . Save them for Caution shortages . that unnecessary mask Continue s ur g ic a l mask to ask patients WITH respiratory on when t he y co me to c l inic . And suggest that sick patients close contact with infants , elderly patients . fresh Te ll pat ien t s t o discard one at least daily . Encourage 1. 2. pat ien ts use to symptoms to wear a mask at home if , or immunocompromised masks t o s tay may contribute when da mp ... and home wh en t hey ' re t o use put a in a sick. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 https://www.cdc .gov/coronavirus/2019-ncov/index.html 3. https://www .cdc.gov/f lu/professionals/infect ioncont rol/maskguidance .htm 4. https://www.who. int/publications-detail/advice-on- the-use -of-mas ks-the-comm unity-durinq-home-care-a nd-in-health-caresettinqs-in-the-context-of-the-novel-coronavirus-(20 19-ncov) -out break Sincerely, Jennifer A. Nieman, PharmD , BCPS Associa te Editor, TRC Healthcare M: 402-660 -4715 E : jnieman@pletter.com W : TRCHealthcare .com Pham1acist's Letter I Prescriber's Letter I Natural Medicines I Pharmacy Technic ian's Letter I Pharmacy Technicians University NIH-001949 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 23:06:37 +0000 Billet, Courtney (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E] FW: [ Dear Prof. Anthony Letter of inte rview from China Science Daily] Can we please get someone to fashion answers for me to edit and send to her. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: ~fm/§ Date: Monday, February 10, 2020 2:54 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: [ Dear Prof. Anthony Letter of interview from China Science Daily] ------ ..-.-,= Dear Prof. Anthony, I am yangmei Han, a journal ist from CHINASCIENCEDAILY. China Sc i ence Dai Iy IS pub I i shed by The Chinese Academy of Sciences. a newspaper in Chinese, Recently, your article " Coronaviru " We are s Infectio ns- More Than Just the Common Cold mention about vaccines research 1n NI AID. interested and there are some questions and get more informations. 1, What is the current research progress about NIH-001950 vaccines 1n NIAID? I want to 2-.. What are the factors restricting the development of vaccines? and did you break through them? 3 .. What is the standard of vaccine that can be injected to patients? and according your forecasting, how will it work? 4 .. Can this vaccines research play a role in the 2019 -nCoV ? Or as a treatment for a common infectious disease in the future? 5, Does vaccines have side effects? how can we restrain it? 6, If vaccines research success in world? if it will , I am looking Will it be open to the what conditions will need for open? if you could, Thank you very a certain country, we would I ike you rep l y as soon as possible much forwa r d to your reply! Si nee re I y yours , Yangmei Han (Miss) ~tw~ q:ioof:.I.~ :1& tt* tnc::p ,1) tc~ BlB~B : ymhan@stimes .cn;576942717@qq .eom it i! : (b)(6) i'!EiJt:~t:l¥nn;i;;El&J:P**1ffi-~Z:,g:i~N~:J: IH± q:iOOf:.1.~ ~tt:~~~M ~ ~-q:i~ I ~~-~*~~M~B~•m~~c::p~M · §&~~~m-~~~~~$·~-~~~~-%~M~••· NIH-001951 ~ ~ * ~~~~ From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 20:54:02 +0000 Natalie Rahhal RE: Interview re: coronavirus patient characteristics If th is is true, which it might not be, there is no clear explanation for why right now . There will likely be studies coming out that say that the relative proportion of male:female is closer to 50:50. Even one of the ones that you quoted was 54% Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone Cb) (6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Natalie Rahhal Date: Tuesday, February 11, 2020 1:55 PM To: Fauci, Anthony (NIH/NIAID) [E] ------- ~= (b)(6) Subject: Interview re: coronavirus patient characteristics Hi Dr Fauci, I'm sure you're extraordinarily busy righ t now, but I've seen several stud ies and reports that coronavirus seems to dispropo rtionate ly strike men (making up 54-68% of cases, depending on which study you reference). I was wondering if you might have any comments to offer on why this mig ht be? Thank you, Natalie A Rahhal Acting US Hea.lth Editor Daily lll4'lil.com NIH-001952 Daily M ail Online I51 Astor Place, 9th floor, New York NY 10003 Tel: +1212402 Mobile : 9086 (b) (6) Tw itter : https ://twi t ter .co m/nata lier78?1ang=en Email: Natalie.rahhal@mailonline.com Disclaimer This e-mail and any attached files are intended for the named addressee only. It contains information, which may be confidential and legally privileged and also protected by copyright. Unless you are the named addressee ( or authorised to receive for the addressee) you may not copy or use it, or disclose it to anyone else. If you received it in error please notify the sender im mediately and then delete it from your system. Associated Newspapers Ltd. Registered Office: Northcliffe House, 2 Derry St, Kensington, London, W8 STT. Registered No 84121 England. NIH-001953 From: To: Fauci, Ant hony (NIH/N IA ID) [E) Tue, 11 Feb 2020 20:10:45 +0000 Nabel, Gary / US Subject: RE: W HO meeti ng Date: Gary: Thanks for the note. (b) (4) Best, Tony Anthony S. Fauci. MD Director National Institute of Allergy and Infectious Diseases Building 3 I, Room 7 A-03 3 I CenterDrive, MSC2520 National Jnstitutes of Health Bethesda, M D 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The infom1ation in this e-mail and any of its attachmen ts is confidential and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recip ient. If you have received this e-mai l in error please inform the sender and delete it from your mailbox or any other storage devices. The Nationa l 1nstitute of Allergy and lnfectious Diseases (NIAI D) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA ID by one of its representatives. -----Original Message----- ---------=-=-= from : Nabel, Gary /US Date: Tuesday, February l l , 2020 1:19 PM (b) ( To: Fauci, Anthony (N1H/N1AJD)[E) Subject: RE: WHO meeting (b)( --------- No t a problem. I j ust wanted you to know that I was w illing to help. (b) (4) Best Gary -----Original Message----From: Fauci, Anthony (NlH/NlAID) [E] Date: Monday, February 10, 2020 3:07 PM --------- To: Nabel , Gary / US (b)( (b)( 6)> NIH-001954 Subject: [EXTERNAL] RE: WHO meeting EXTERNAL: Real sender is _______ _, (b)(6) T submitted your name to the group as one ofmy priority suggestions. T have no idea whom they wil l select. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 3 1, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (301) 496-2263 FAX: (301) 496-4409 E-mail: afauci@niaid.nih.gov The infom1ationin this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox.or any other storage devices. The National Instinite of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIA.lDby one of its representatives. -----O riginal Message- ---From: Nabel, Gary / US ---------=--=-= (b) ( Date: Monday, February I 0, 2020 2: 17 PM To: Fauci. Anthony (NTH/NIAlD)[E]-------~~ ______ Subject: WHO meeting _ )_C_, Cb Hi Tony Thanks for taking the time to talk and help with the HTVtrispecific work last week. I appreciate your efforts. While 1 was there, you mentioned a WHO Coronavirus meeting you thought l should join. I'm happy to attend but have not yet received an invite. Sometimes WHO excludes companies from such meetings, which is unfortunate and to their detriment. In any case, please let me know ifl can help in any way. Best regards Gary Sent from my iPhone NIH-001955 From: Date: (b)(6) Cc: Tue, 11 Feb 2020 11:22:43 -0500 Mart in Blaser Conrad, Patricia (NIH/NIAID) [E];Cassetti,Cristina (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E] Subject: Re: SARS2003, Influenza 2009 and the present To: Marty: Than.ks for the note . Indeed, immune sera is foremost on our mind as are mAbs . Hope that all is well with you. Best, Tony On Feb 11, 2020 , at 9:55 AM , Martin Blase r Cb)( wrote: ------------ Dear Tony, I dont mean to bother you, but I have a suggestion, in case you have not considered it. China will have hundreds of thousands of Coronavirus surv ivors . Thei r convalescent (immune) serum is valuable. China should try to collect it and give it as a good-will gesture to people around the world. For moderately to seriously ill people, Immune serum should save many lives. If cases start to come here, we also should collect serum from survivors, but hopefully we will be very late in t he pandemic, and it is not needed because of all of the others th ings you are doing. Thank you for everything you and NIAID are doing! Best wishes, Marty (Just as in SARS,the Ro for nCo-2019 is higher in hospitals than in the community, but it still is too high in the community). Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Professor of Medicine and Microbiology-RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers University 679 Hoes Lane West, Room 106A Piscataway, NJ 08854 ------ (b)(6) Office Phone: Fax: 7 2-235- fi._ 3__ 1_8 ______ Emili ~= oo~ NIH-001956 httPs ://cab m .rutgers.edu From: Fauci, Anthony (NIH/NIAID) [El ________ ...... (b)(6) Date: Sunday, January 26, 2020 7:16 PM To: Martin Blaser (b)(6): Cc: Conrad, Patricia (NIH/NIAID) (El Subject: RE:SARS2003, Influenza 2009 and the present (b)(6) Marty: Many thanks. Th is is very helpful. Best regards, Tony From: Martin Blaser (b) (6) Date: Saturday, January 25, 2020 9:35 AM ------~ = To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: SARS2003, Influenza 2009 and the present Webb G, Blaser MJ, Zhu H, Ardal S, Wu J. Critic al role of nosocomial transm ission in the Toronto SARS outbreak. Mathematical Bioscie nces and Engineering 2004 ; 1: 1-13. [PMID: 203699561 [Paper of the year, 2004] Webb GF, Hsieh Y-H, Wu J, Blaser MJ. Pre -symptomatic influenza transmission, surveillance, and school closings: implicat ions for novel influenza A (HlNl). Mathematical Modelling of Natural Ph enomena 2010 ; 5:191-205. Dear Tony, Thank s for your JAMA piece on 2019-nCoV. Perh aps I can help in a small way: In 2003, with SARS, the Ro was initially considered to be over 2, but in fact that was the conflation of the nosocomial and community rates. In the 2004 paper , we showed that nosocomial rate was much higher, and that the Ro in the commun ity was between 1 and 2. A lower Ro in the community accounts for why modera te public health action s could mo ve it toward extinction--and why it propagated in Beijing , but not Shanghai , in Toronto NIH-001957 but not in Vancouver--the Ro in North America became less than one pretty quickly. To me , one important aspect is the control of respiratory tran smission in the hospital, avoiding extensive nebulization /aerosolization, or doing so in negative pressure rooms , as for TB isolation. (Treating patient s with robot s is a good idea!) In the communit y, standard public health quarantine, contact tracing should be sufficient for staiie rs. Although hundreds of cases are reported in China, the actua l number of infections is likely much higher. The 41 deaths are the tip of the iceberg of not 800 infections (5% fatality rate), but maybe 8,000 infect ions (0.5%) . Although that rate is much better, if the mutating virus becomes very contagious- then the impac t could be similar to 1918 flu. That's why containment is so important-and although draconia n, the Chinese government is doing the right thing (as far as we know). When a new pathogen arrives, children often have mild disease but they are important vectors for transmi ssion in the cotrununity , reaching many households. The second paper is the imp01iance of closing school s to minimi ze transmi ssion- This was for flu with a short (pre-symptomatic) incubation , but may be even more relevant for 2019-nCo V. It is much too eai·ly to even think of this in the USA , but it may come to this--and sooner will be better than later , when that time point comes . Happy to help, any way that I can. Thank you for all you and NIAID are doing!!! Best wishes , Marty NIH-001958 Martin J. Blaser, M.D. Henry Rutgers Chair of the Human Microbiome Profe ssor of Medicine and Microbi ology- RWJMS Director, Center for Advanced Biotechnology and Medicine Rutgers Uni vers ity 679 Hoe s Lane West , Room 106A Piscatawa y, NJ 08854 Office Phon e: Fax: 732-235-53 ·-18 ------~ (b)(6) Emai l http s: I Icabm.rutgers.edu ---------------- = (b) (6) NIH-001959 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:22:53 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview/ Coronavirus vaccine - Pazienti.it Have Jen Routh or someone prepare bri ef responses that I can check. Thank s. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Alessandra Lucivero Date: Tuesday, February 11, 2020 5:35 AM To: Fauci, Anthony (NIH/NIAID) [E) Cb)( > Cc: Camilla Mantegazza ; Irene Bacca Subject: Interview/ Coronavirus vaccine - Pazienti.it ------~~ Good morning prof. Fauci, my name is Alessandra Lucivero and I'm the Editorial Manager of Pazienti.it , an It alian health webs ite, followed by over 3 million users every month . We would like to ask you some questions related to the Coronavirus vaccine. We will publish the interview in Ita lian on our blog here: htt ps://www .pazient i.it /n ews-di-salute. The questions are: • Coronavirus vaccine: when will it be available? What are the difficulties? • Could the Coronavirus mutate, if a vaccine cannot be found in time? • Will the vaccine be the solution against Coronavirus? I hope you can be kind enough to answer my questions . I look forward to hearing from you. Thank you very much fo r you r time. Alessandra Lucivero NIH-001960 Alessandra Lucivero Responsabile editoriale alessandra. I ucivero@ pazienti.it Pa z Ie n T 1.it II portale della salute dove farsi vedere da uno bravo. Pa:u enTL Questo messaggio e i suoi al/egati sono indirizzati esclusivamente a/le persone indicate . La diffusione, la modifica, la riproduzione di queste informazioni sono vietate . Qualora abbiate ricevuto questo documento per errore, vi preghiamo di comunicarlo al mittente e di provvedere al/a sua eliminazione . Vi injormiamo inoltre che questo indirizzo di posta eutilizzato solo a scopo professionale: non si garantisce che la corrispondenza verso questa easel/a venga Jetta dal solo destinatario poiche, in determinate circostante, /'accesso puo avvenire anche da parte di terzi appartenenti al/a Societa. Pertanto si consiglia di non inviare messaggi di natura personale. Grazie. NIH-001961 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 13:14:45 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Coronavirus Auto Terminat ion Retrovirus Auto Termination.PDF Please handle . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Pali Nazir (b)(6)> Se nt: Tuesday, February 11, 2020 4:32 AM To: Fauci, Anthony (NIH/NIAID) [E) ---------=-:-= Chun, Tae-Wook (NIH/NIAID) [E] (b)(6) (b)( ; Connors , Mark {NIH/NIA ID) [E] '7"":°'.":"":'"'.:-'.'"'.""'.":'-:-7::-;::===.;,__-~= (NIH/NIAID) [El (b)(6); lusso, Paolo {NIH/N IAID) (NIH/NIAID) [El =====~ (b::;: ) ~(6) (b)( [El Subject: Coronavirus Auto Term ination Dear Mrs . / Sir, We have a solution to the new recent global problem Coronavir us (2019-nCoV). Best Regards, Dr. Pali Nazir NIH-001962 ; Lane, Cliff (b)(6J>; Sereti, lrini From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Tue, 11 Feb 202013:12:28 +0000 Cassetti, Cristina (NIH/NIAID) [E) FW: coronaviruses Please handle. Thanks. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Cen ter Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892 -2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sen der and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAID) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: (b)( · Date: Tuesday, February 11, 2020 8:0 I AM To (b)(6) Holbrook , Michael (NIH/NlAID) [CJ .__ ______ Cb _H....,>; Fauc i, Anthony (NIH/NlA1D)[E].__ _____ Cb _H_,, Subject: coronaviruses He llo, Working as an occupational physi cian iu F1ance, I would like to draw you r attention to the antiviral activity of proton pump inhibitors , includin g for the Gibbon Ape Leukemia vims , a virus which does not requir e acidification of eod osomes for entry into ce lls, as is the case with corona viruses. Indeed, in 2015 Long et al. (I) found that« ... The common ly used proton pump inhib itors, Om eprazole and Esomep razole were also able to inhibit entry of all PV s tested but at high er dru g concentrations than may be achiev ed in vivo ... >> . Us ing omepra zole and esomeprazole magncsi11m hydrate, prepared in sterile DMSO (Sigma ), they conc luded that« ... OM and ESOM appeared to decrease fluorescence, and therefore increase endosomal pH , only at a concentration of200µM, higher than that required to inhi bit PV entry . Moreover cellular toxicity was observed at this concentration after 24 hours ... ». In 2016, Dowa ll et al. (2) found : « ...Whereas omeprazole and esomeprazole demonstrated in vitro activity against EBOV , the results were in line with a previou s report using pseudotyped viruses where the values of drug concentration caus ing 50% inh ibition (IC50) were in the region of 50 µM [10). This suggeste d that doses requi red for potent inh ibition wou ld be difficult to achieve without concomitant and significant toxicity (the licenced dosing for 40 mg esomeprazole , 20 mg esomep razole and 20 mg omeprazo le generates median maximum plasma concentrations of 1.59- 9.61 ~tM, 0.51-4.78 µMand 0.15-3.51 µM , respectively .. . >>. However, omeprazole is marketed in a non-ionized form and must be ionized (in acidic environment) to be NIH-001963 transformed into an active molecule(3). lt is the ionized form which establishes covalent bonds with the SH group of the cysteine of the a subunit of the proton pump. The solution used in 2015 by Jason Long et al. was , as in 2016 by Dowall et al., DMSO(Dimethyl Sulfoxide). DMSO is a polar and aprotic organic solvent with dissociation constant pKa = 35.1 This is probably an exp lanation for the surpr ising findings from these studies regarding proton pump inhibitors: Inhibition of viruses at I 00 µM (at 50 µM esomeprazo le for 4 of the 5 viruses tested) and increase in endosomal pH only at a concentration of200 ~1M. This is a situat ion which, from my point of view, does not reflect the human tissue situation, because in this sin,ation omeprazole can be ionized in the intracellular space but also already in the extrace llular space. Besides, that's probably its advantage: to be ionized and activated where there is an acidic enviro nmen t. Without taking into account the tissue situatio n and the need that omeprazole must be ionized to be transformed into an active molecule, it would not be possible to explain the following publications , since it would be impo ssible to obtain tissue concentrations required: <> (4) <> (7) « Proton pump inhibitors for chronic obstrnctive pulmonmy disease » (8) « The ngH,K-A TPase shares approximately 65% sequence homology with the gH,K-ATPase » (9) « Omeprazole blocked another P-type ATPase, ATP7 A (Men kes protein) in human epidermal melanocytes » (10) « pH-dependent anti tumor activity of proton pump inhibitors» ( 11) « V-ATPase as a candidate target molecrtle or biomarker for cancer treatment and provide a potential role for omeprazole as a chemosensitizer in clear cell carcinoma of the ovaiy » (12) « Proton pump inhibitors such as omeprazole, used clinically to suppress gastric acid ity in gastritis, are activated by acidic conditions and tend to decrease intracellular pH and increase the extrace llular pH via inhibition of V-ATPases in a covalent interaction» ( 13) « proton pump inhibitors have been shown to be highly effective at inhibiting V-ATPases in vitro» (14) Specifically at the pulmonary level, we observe concerning proton pump inhibitors: « ... Since ATP 12A shares approximately 65% identity with the gastric H+/K+-ATPase (ATP4A), we investigated the potential of using clinically approved A TP4A proton pump inhibitors (PPTs) for their ability to restore ASL pH in CF hAECs. We show that, despite not expressing ATP4A transcripts, acute exposure to the PPJ esomeprezo le, produced changes in intracellular pH that were consistent with the inhibition ofH + secretion , but this response was independent of ATP 12A. More importantly , chronic exposu re of CF hAECs to esomeprazo le alka linized the ASL without disrupting the epithe lial barrier integrity, but this increase in ASL pH was cons istent with a decrease in mRNA expression of ATPI.2A. We conc lude that PPis may offer a new approach to restore ASL pH in CF airways , which is independent ofCFTR .... » (15) NIH-001964 « ... On the other hand, even though the gastric H+/K +-ATPase was not expressed in airway epithelial cells, exposure to esomeprazole acidified the cytosol and increased ASL pH of primary CF hAECs. We show that esomeprazo le had a dual mechanism of action: acutely , it induced intracellular acidification in an ATP l 2Aindependent manner but, chronic exposure, which importantly did not have any deleterious effect on epithelial integrity , was linked to decreased ATP 12A mRNA levels. These results open up the possibility ofrepurposing PPTs as a new therapeutic approach for treating CF lung disease ... » ( 15) « ... we found that the mRNA of ATP 12A, the non-gastric H+/K +-A TPase , shares 70% identity with the gastric H+/K+-ATPase, ATP4A mRNA, which translates to around 65% identity in the protein products ... » (15) « Proton pump inhibitor therapy predisposes to increased risk of developing pneumonia » ( 16) « Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia » (17) « ATP4a is required for development and function of the Xenopus mucoci liary epidermis - a potential model to study proton pump inhibitor-associated pneumonia>> (18) Regarding coronaviruses and Golgi complex: « ...Coronavirnses (Co Vs) acquire their envelopes from the endoplasmic reticulum-Golgi intermediate compartment( ... ), also called the cis-Golgi network( ... ). The three main envelope proteins (S, Mand E) are synthesized in the ER and move to the ERGIC /Golgi region where they orchestrate assembly of virus by interacting with the viral nucleocapsid ( ... ).Once virions have budded into the lumen of the ERGlC, the ~ 120 nm particles must move through the host secretory pathway to be released from infected cells. Coronaviruses are believed to follow the constitutive secretory pathway for exocytosis , although only a few stud ies have addressed the release of virions. During infection , a progressive dismption of Golgi structure is observed , with swollen unstacked cistemae late in infection ... >> « . .. Weak bases (w hich disrupt acid ification), v-ATPase inhibitors , and expression of a pH activated proton channel all block a number of membrane trafficking steps( . . .) One mechanism for how luminal pH can affect vesicu lar trafficking involves a subunit of the membrane sector of the v-A TPase, which has been shown to act as a pH sensor in endosomes. This subun it undergoes a conformationa l change as the luminal pH drops, which recruits cytoplasmic machinery leading to subsequent vesicle fonnation ... » (19) « ... Phannacological and other manipulations of the pH gradient that resu lt in neutralization of the lumen have all been shown to cause slow trafficking of cargo through the Golgi complex as well as alteration in Golgi morphology ... » « ... Similar to M2, the infectious bronchitis virus (IBV) coronavirus E protein elicits multiple secretory pathway disruption phenotypes when overexpressed in mammalian cells ... » (20) « ...The envelope protein (E) of corona v iruses plays an important role in virus assembly ( ... ) Using coronavirus infectious clones , it was shown that the transmissible gastroenteritis virus E protein is essential for vims production , and murine hepatitis virus lacking E protein is viable but extremely debilitated ... >> « ... The exact mechanism of coronavirus release after budding into the endoplasmic reticulum--Golgi intermediate compartment is not known. Large vacuoles containing budded virions are obse1ved in infected cells , presumably en route to the plasma membrane where fusion of the vacuole results in release of virions ... » (21, 22) « ... It might be worth investigating whether ion-channel inhibitors, such as amantadine, or proton pump inhibitors specifically are able to inhibit this increase in Go lgi pH . For now, though , it still remains to be seen whether Co V release is mediated by viroporin ion channel activity or through PP Is with host proteins of the secretory pathway ... » (23) « V-A TPases are also important for transportation of new ly synthesized acid hydrolases from Golgi to lysosomes » (24) NIH-001965 «...cardiotonic steroids ouabain and bufalin, wbicb are known not to affect tbe transport function ofNa+,K +AT Pase, inhibited infection of ceUs with MHV, FIPV, Mid dle East respiratory syndrome (MERS)-CoV, and VSV, but not IAV, when the compounds were present during virus inoculation . Card iotonic steroids were shown to inhibit entry ofMHV at an early stage, resulting in accumulation ofvirions close to the cell surface and, as a consequence, in reduced fusion. In agreement with an early block in infection, the inhibition ofVSV by CTSs could be bypassed by low-pH shock. Viral RNA replication was not affected when thes e compounds were added after virus entry. The antiviral effect of ouabain could be relieved by the addition of different Src kinase inhibitors , indicating that Src signaling mediated via ATPIAI plays a crucial role in the inhibition ofCoV and VSV infections ...» (25) In conclusion, in order to verify the possible efficacy of omeprazole and esomeprazo le in the control of infection by coronaviruses : Tbe equivalent oftbe maximum serum concentration that can be obtained in the human bod y should be used and tested in active (ionized) form in vitro . Unlike an in vitro test, the human body is an open system, a dissipative system. However, local concentrations oftbe ionized form should not exceed serum concentrations of the inactive non-ionized form in the absence of active transport. But the transfonnation from the non-ionized form to the ionized form could continue until the saturation of the reactions at the cellular ]eve] or until the depletion of the transformation capacity from the inact ive form to an active form, linked to a change in acidity or the depletion of the inactive form. As omeprazole can modify or even inhibit the action of the M2 protein of the influenza virus at the cellular level (26), based on a computer simulation test, it would be desirable to cbeck the interaction capabilities of omeprazole with protein E of the corona virus . Prot ein E is likely to resemb le the protein M2 in its mode of action. In the absence of a treatment recognized as effective in the context of a coronavirus infection and in the absence of data clearly demonstrating the ineffectiveness of omeprazole , personally, l would be tempted to take omeprazole after being in contact (at a distance of less than 2 to 3 meters) with people at risk of contamination or if l had the first symptoms, hoping for the inhibitory activity of omeprazole on P-type ATPases (27, 28) in the context of coronavirus exocytosis , in analogy to the action "off target on the endosoma l v ATPase" during endocytosis processes. This step, if effective, will not prevent infection , but could lesse n its importance, slow the process down and give tbe immun e syste m a complementary option to defend itself... Personal experience, using omeprazole in the context of seasonal respiratory v iral infections since 2007, reminds me of the indication to divide the daily dose into two daily doses (omeprazole 10mg morning and evening is usually already effective for seasonal respiratory viral infections). According to tbe evolution and the importance of inflammatory state I associate an antihistamine, eg cetirizine. In the context of the coronavirus , I would be tempted share tbe maximum permissible daily dose of omeprazole in 3 divided doses after being in contact with people at risk of contamination at a distance of less than 2 to 3 meters divide tbe daily dose of omeprazole into two daily doses in case of minor symptoms take the daily dose of omeprazole in a single dose if the symptom s worsen with repercu ssions on the genera l condition to resume the daily dose of omeprazole in two daily doses when the symptoms of sever ity diminish. Th e effectiveness of esomeprazole may be greater than omeprazole. NIH-001966 Taking into account the aforement ioned publications , it should not be forgotten that omeprazo le will reduce sec retions at the respiratory level. A posit ive effect on respiratory secret ions dur ing acute vira l respi ratory diseases which can become negative (by modifying the pH, the cil iary mobility and the volume of secretio ns) during prolo nged use, thus promoting the risk of bacterial pneumonia (29). The adva ntages and d isadvantages may vary depending on the user phenotype of omeprazole with regard to cytochrome P 450 (30). Best regards Johann es Hambura I. Long J, Wright E, Mo lesti E, Temperton N, Barclay W. Antiviral therapies against Ebola and other emerging vira l diseases using existing medicines that block v irus entry. Fl000Res. 2015;4:30 . Published 2015 Jan 29. doi: 10.12688/fl000research .6085 .2 2. Dowall SD, Bewley K, Watson RJ, et al. Antiviral Screening of Multiple Compounds again st Ebo la Virus. Viruses. 2016;8(11):277. Published 2016 Oct 27. doi : 10.3390/v8110277 3. Shin JM , Kim N. Pbarmacokinetics and pharmacodynamics oftbe proton pump inhibitors. J Neurogastroenterol Motil. 2013;19(1):25-35 . doi: 10.5056/jnm.2013.19.1.25 4. Spugnini EP, Citro G, Fais S. Proton pump inhibitors as anti vacuo lar-ATPases drugs: a novel antica ncer strategy. J Exp Clin Cance r Res.20 10;29( 1):44. Pub lished 2010 May 8. doi: 10.1186/1756-9966 -29-44 5. Sasaki T, Yamaya M, Yasuda H, Inoue D, Yamada M, Kub o H, Nish imur a H, Sasak i H. The proton pump inhibitor lansoprazole inhibit s rhinoviru s infection in cultured human tracheal epit helia l cells. Eur J Pharmacol. 2005;14:201 - 2 10. do i: 10.1016/j .ejphar.2004 . 12.042. 6. Gaspari ni R, La i PL, Casabona F, et a l. Do the omeprazole fami ly compounds exert a protect ive effect against influenza- like illness? . BMC Infect Dis. 20 14 ; 14:297. Publ ished 2014 Jun 2. do i: 10.1186/1471 -2334-14 -297 7. Moorn1ann AEBDP , Flynn DL, Hui LI, Villam il CI, Inventor method of using (H+/K+)ATPase inhibitors as antiviral agents . United States 1999 Jun. 14, 2005. 8. Kikuchi S, Naoki Y, Tajiri T, Watanabe N . Proton pump inhibitors for chronic obstructi ve pulmonary disease. Cochrane Database Syst Rev . 2018;2018(8) :CD013 l 13. Published 2018 Aug 30. doi:10.1002 / 14651858.CD013 I 13 9. Modyanov N, Pestov N, Adams G, Crambert G, Tillekeratne M, Zhao H, Korneenko T, Shakhparonov M, Geering K. Nongastric H ,K-ATPase: structure and func tional properties. Ann NY Acad Sci. 2003 Apr; 986():183-7 . 10. Matsui MS, Petris MJ , Niki Y, Karaman-Jurukovska N, Muizzuddin N, Ichihashi M, Yarosh DB. Omeprazole , a gastric proton pump inhibitor , inhibits melanogenesis by blocking ATP7 A trafficking. J Invest Dermatol. 2015 Mar ; 135(3):834-841. l I . De Milito A, Canese R , Mari no ML, Borghi M, Tero M, Villa A, Venturi G, Lozupone F, Jessi E , Logozzi M, Mina PD, Santi nam i M , Rodo lfo M, Podo F, Rivoltini L, Fais S. pH-dependent antih tmor activity of proto n pump inhibitors aga inst human melanoma is mediated by inhibitio n of tumor acid ity. Int J Ca ncer. 2009 . 12. Lee YY, Jeon HK, Hong JE, et al. Proton pump inhibit ors enhanc e the effects of cytotoxic agents in chemo resistant epit helial ovar ian carcinoma. Oncotarg et. 2015;6(33):35040 - 35050 . doi:10.18632 /oncotarget.5319 13. Larsson H, Mattson H, Sundell G, Carlsson E. Animal pharma codynamics of omeprazole. A survey of its NIH-001967 pharmacological properties in vivo. Scand J Gastroenterol Suppl. l 985; I08:23-35. 14. Luciani F, Spada M, De Milito A, Molinari A, Rivoltini L, Montinaro A, Marra M, Lugini L, Logozzi M, Lozupone F, Federici C, Tessi E, Panniani G, Arancia G, Belardelli F, Fais S. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst. 2004;96: 1702-1713. 15. Delpiano L, Thomas JJ, Yates AR, Rice SJ, Gray MA, Saint-Criq V. Esomeprazo le Increases Airway Surface Liquid pH in Primary Cystic Fibros is Epithelial Cells. Front Pharmacol.2018 ;9: 1462. Published 20 18 Dec 11. doi: 10.3389/ fphar.2018.01462 16. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk -Lafeber AB, Siersema PD, Kusters GC, Laheij RJ. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumonjae pneumonia. A liment Phannacol Ther. 2012 Nov;36(10):94l-9. doi : 10.1111/apt.12069. Epub 2012 Oct 3. 17. Sun DI, Tasca A, Haas M , et al. Na+/H+ Exchangers Are Required for the Development and Function of Vertebrate Mucociliary Epithelia. Cells Tissues Organs. 2018;205(5-6):279 - 292. doi: 10.1159/000492973 18. Walentek P, Beyer T, Hagenlocher C, et al. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015;408(2):292-304. doi: I0.1016/j.ydbio.2015.03.013 19. Machamer CE. Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol. 2013; 140(3):261269. doi: 10.1007/s00418-013-1120-y 20. Jason W. Westerbeck, Carolyn E. Machamer. The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH To Protect the Spike Protein and Promote the Release oflnfectious Virus. Journal of Virology May 2019, 93 (11) e00015- 19; DOI: 10.l 128/M .00015-19 21. Machamer CE 1, Youn S. The transmembrane domain of the infectious bronchitis vims E protein is required for efficient virus release . Johns Hopkins University School of Medicine , Baltimore , Ma1yland 21205, USA. PMID: 17037529 DOI: 10.1007/978-0-387-33012-9 33 22. Tooze, J., Tooze, S. A., and Fuller, S. D., 1987, Sorting of progeny coronavirus from condensed secretory proteins at the exit from the trans-Golgi network of AtT20 cells, J. Cell Biol. I05: 1215. 23. Schoeman, D., Fielding, B.C. Coronavirus envelope protein: current knowledge. Virol J 16, 69 (2019). https://doi.org/ 10.1186/s l2985-019-1182-0 24. Pamar thy S, Kulshrestha A, Katara GK, Beaman KD. The curious case ofvacuolar ATPase: regulation of signaling pathways. Mo] Cancer. 2018; 17(1):4 L Published 2018 Feb 15. doi: I0.1 I 86/s 12943-018-0811-3 25. Burkard C, Verheije MH, Haagmans BL, van Kuppeveld FJ, Rottier PJM, Bosch B-J, de Haan CAM. 2015. ATPlAl-mediated Src signaling inhibits coronavirus entry into host cells. J Virol 89:4434-4448. doi:10.l 128/JVI.03274-14 26. Bozdaganyan M, Orekhov Ph, Bragazzi N, Panatto D, Amicizia D, Pechkova E, Nicolini C, Gasparini R. Docking and Molecular Dynamics (MD) Simulations in Potential Drngs Discovery: An Application to Influenza Virus M2 Protein. American Journal of Biochemistry and Biotechnology 2014/ 11/08. 10.3844/ajbbsp.2014.180.188 27. Lisa A. Dunbar and Michael J. Caplan. Jon Pumps in Polarized Ce lls: So1iing and Regulation of the Na+ ,K+and H+,K+-ATPases. J. Biol. Chem. 2001 276: 29617-. doi: I 0.1074/jbc.R I 00023200 28. Amarelle L, Lecuona E. The Antiviral Effects ofNa ,K-ATPase Inhibition: A Minireview. Int J Mol Sci. 2018;19(8):2154. Published 2018 Jul 24. doi: 10.3390/ijmsl 9082154 29. Yu LY, Sun LN, Zhang XH, et al. A Review of the Novel Application and Potential Adverse Effects of Proton NIH-001968 Pump Inhibitors. Adv Ther. 2017 ;34(5): I 070-1086. doi: I 0.1007 /s12325-017-0532-9 30. E l Rouby N, Lima JJ, Johnson JA . Proton pump inhibitors: from CYP2C 19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018; 14(4):447-460. doi: 10.1080/17425255.2018.146 1835 NIH-001969 Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:52:45 +0000 Conrad, Patricia (NIH/NIAID) [El RE: WTOP Request From: Date: To: Subj ect : OK by me. Please set it up. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Conrad, Patricia (NIH/NIAID) [El Date: Tuesday, February 11, 2020 7:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subj ect : Fwd: WTOP Request (b)(6)> --------, .....,....,= --------- (b)(6) 1040 before you depart for aspen event? Sent from my iPhone Begin forwarded message: From: "Chesson, Joslyn" Dat e: February 11, 2020 at 7:16:26 AM EST To: "Conrad, Patricia (NIH/NIAID) [E]" _______ -,;;(b)~ (=6)> Subject: WTOP Requ est Good morning, Hoping Dr. Fauci has some availability this late morning and early afternoon to discuss the coronavirus and the quarantining on cruise ships. We have 10:40a, 11:lOa, and 12:10pm all open . NIH-001973 Let me know if any of those times work for him! Thanks, Joslyn Chesson Editor WTOP News (202) 895-5060 NIH-001974 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 11 Feb 2020 12:20:02 +0000 To: Lisa Monaco Subject: RE:The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare Lisa: Thanks for the note and for sending this. Very ruce piece! I hope that all is well w ith you. I miss very much our interactions. Best regards , Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and Tnfectious Disease s Bui lding 31, Room 7A-03 31 Center Drive, MSC 2520 National In stitutes of Health Be thesda , MD 20892-2520 Phone: (b) (6) FAX: (30 I) 496 -4409 E-mail (b) (6) The infom1ation in this e-ma il and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Tnfectious Diseases (NIAID) shall not accept liability for any statement s made that are the sender's own and not express ly made on behal f of the NIAID by on e of its representatives. -----Orig ina l Message----From: Lisa Monaco _______ ..., (b "~"' ..., (6) = Date: Monday,febrnary 10, 2020 8:09 PM To: Lisa Monaco (b)(6) Subject: The Coronavirus Shows Why the U.S. Must Make Pandemic Disease a National Security Priority - Lawfare In case you missed this, my latest on the coronovirus. https:/lwww .lawfareb log .com/co ronavirus -show s-whv-us-must-make -pandemic-disease -national-security-priority Sent from my iPad NIH-001975 From: Date: To: Cc: (NIH/NIAID) [E];Lerner, Subject: Att achment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 22:44:53 +0000 Routh, Jennifer (NIH/NIAID) [E] Conrad, Patricia (NIH/NIAID) [E];Billet , Courtney (NIH/NIAID) [E];Stover, Kathy Andrea (NIH/NIAID ) [E];Folkers, Greg (NIH/NIAID ) [E] RE: for review: responses for Washington Times responses to Washington Times 2.10.2020 AL - wit h Fauci tracked changes.docx See my tr acke d changes in at tached docum ent . Thank s. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Routh, Jennifer (NIH/NIAID) [E] Sen t : Monday, February 10, 2020 4:07 PM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Cc: Conrad, Patricia (NIH/NIA ID) [El (b)(6)>; Billet, Courtney (NIH/NIA ID) [E) (b)(6); Stover, Kathy (NIH/NIAID) [El (b)( ·; Lerner, Andrea ""-:--:--"'"""'."'-:-:-::-==:::::.:...--,.;_-=-c-c-=-t (NIH/NIAID) [E_______ Cb _>_<6JFolkers, Greg (NIH/N IAID) [E]_______ Cb _H_6)> --------- ------ ::;..,..-,= ~======~~ Subject: for review: responses for Wash ington Times Dr. Fauci The reporter Shen Wu Tan from the Washington Times reached out to us this morning with some questions about 2019-nCoV. I drafted proposed responses t o t hese questions with input from Andrea. Please see attached. Please let me know if you have edits . I w ill send the final responses back to t he reporter, and I will note they are attributed to you . Thanks, Jen Jennifer Routh [E] News and Science Writ ing Branch Office of Communications and Government Relations NIH-001980 National Institute of Allergy a nd Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)(6) CbH Disclaimer : The information in this e-mail and any of its attachments is confidential and may conta in sensitive informa tion. It should not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sende r and delete ii from you r mail box or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liab ility for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. NIH-00198 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:22:28 +0000 Routh, Jennifer (NIH/NIAID) [E] FW: Wpos t : Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? Let us di scuss. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Bui lding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sen sitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. (b) (6)> From: Folkers, Greg (NIH/NIA ID) [E) Date: Monday, February 10, 2020 2:37 PM Subject: Wpost: Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? -------- Opinions Q&A with Anthony Fauci: Are we past the point of containment for coronavirus? NIH-001982 man wears a protective mask while walking in Wuhan, China, on Feb. 10. (Stringer/AFP/Getty Images) By Robert Gebelhoff Assistant editor and Opinions contribu t or Feb. 10, 2020 at 2:22 p.m. EST The latest strain of corona virus continues to rage across Chino. Its death tolf has surpassed 900, eclipsing the body count from Chino's SARS outbreak in 2002 and 2003 . To get a better sense of the disease and the U.S. government's response to it, we spoke to Anthony 5. Fauci, immunologist and director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Below is a transcript of an interview with Fauci, edited for clarity and brevity . Robert Gebelhoff: Right off the bat, what makes this virus different? Anthony Fauci: Well, we have to be concerned whenever there's a virus that has - and I'm going to use a big word here - pathogenic potential. ... [The coronavirus] is brand-new, and there's no real underlying experience with it, so the general population is naive with regard to protection . And it has serious potential, because it's already spreading rapidly . It' s the unknown aspect of something that already tells you it's a serious problem. We don' t know where it's going. Gebelhoff : Are we past the point of containment for this coronavirus? Fauci: No, we're not. The short answer is we're not past the point of containment. But it really does have the potential to turn into a global pandemic . What we have now is a very serious epidemic in China.. .. [But outside of China,] there is very little - but some - transmission from person to person . Once you get mult iple countries that have sustained transmission from person to person, then it 's beyond the situation where you can contain it. You can only mitigate it. In the United States, we are clearly in the containment phase .... And what we've done is we've identified . We've isolated . And we've done contact-tracing [identifying who might have come in contact with an infected person]. That seems to be successful. But once it it starts spreading all over the world ... then it's almost inevitable that it's going to start spreading here . Gebelhoff : The Post reported last week t hat China withheld information from the public, including silencing medical professionals, and that this made the spread of the virus worse. How does the United States work with a governm ent t hat we can't even trust to tell the tru th to its people? NIH-001983 Fauci: That is an issue. And it's the reason why I have been saying that we need some of our people CDC,NIH people - there on the ground , both help ing and seeing with their own eyes exactly the extent of this. We want to be part of a [World Health Organization] convening group that goes there. But thus far, we've not been able to make that a reality. Gebelhoff: And why's that? Fauci: I don't know . We have asked. We have colleagues - scientific colleagues - in China that we've dealt with for years if not decades. Many of them have trained in the United States. And we know them as friends and as colleagues. They are the ones that are not holding back.... But they're not the ones that make the official proclamations of what comes out. The solution to the problem in the question you're posing is that we really do want people there, so that we can not only help them but also provide some expertise that might supplement or complement their own expertise. Gebelhoff : What does the United States do if [the coronavirus] does become a pandemic in the developing world? Fauci: We ll obviously we will try to help them to contain as best as possible .... Right now, by definition, it is not truly a global pandemic. It is a very serious outbreak and epidemic in China, but the amount of sustained transmission outside of China is still minimal. ... But there are some countries where it is going to be very difficult to stop the evolution into sustained transmission. Obviously the [World Health Organization] and the global security network that we put up over the years will try to help those countries, but there's no guarantee that we'll be successful. Gebelhoff: On that point, the head of the WHO has crit icized travel bans and restrictions around the world as not helpful to stopping the outbreak. He said it was potentially "increas ing fear and stigma ." What Fauci: Everyone agrees that travel bans and restrictions are almost never successful In completely stopping something is that invariably going to turn into a pandemic .... What we are trying to do is to pause temporarily and give China enough time to put the lid on [th is virus] to prevent it from becoming global and to give us a little more time to prepare. There's no indication or imagination that if this becomes a global pandemic that travel restrictions are going to mean anything . But they can mean something , as a temporizing activity. Gebelhoff : What should the average person be doing right now about coronavirus? Fauci: It's a good question . 1) They should realize at this point, it is a low risk. And 2) that risk can change, so pay attention to what's going on [and] to the ... announcements coming from the CDC.... The things that you do for influenza - get vaccinated, wash your hands, avoid crowded places - are exactly the same things that you would do if we did get coronavirus here. So the question is, should we do anything different from what we're already doing? No. Should we all be wearing a mask? Absolutely not. Read more: The Post's View : The virus th at shook China's system Chen Guangcheng : Warning: Chinese aut horit arianism is hazardous t o your healt h David Ignatius: The coron avirus out break shows t he vulnerability of t he 'Chinese model' John M. Barry: Can th is virus be contained ? Pro bably not . John Pomfr et: The coro navirus reawakens old racist t ropes against Chinese peop le Robert Gebelhoff NIH-001984 Robert Gebelhoff is an assistant editor for The Post's Opinions section . He has been with The Post since 2015 .Follow Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those ofNTATD, NTH, HHS , or the U.S. governme nt. NIH-001985 From: Date: To: Subject: Infec tion Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 20:18:24 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Potentia l Treament Strategy to Reduce Motality Caused by Coronavirus NIAID in quiri es, Please Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6) From: Se nt: Monday, February 10, 2020 3:02 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Potential Treament Strate gy to Reduce Motality Caused by Coronavi rus Infectio n -----------------------~~ = Dear Dr. Fauci: One effect ive way to get th ings done is through the individuals like yo u at t he frontline with authorities . I know tha t you are very busy, and I am sorry to bother you. You probably already knew what I'm going to say and appear to be so relaxed. With the significant concern for the quick spread of coronavirus infect ion, I would like to propose a cellbased immunomodulation strategy to reduce the "cytokine storm", the main pathophysiologcal cause for t he mortal ity . The scientific rationale regarding this strategy has been parti ally discussed in an art icle entitled " Extending t he Hor izon of Cell Based lmmunotherapy by Understand ing the Mechanisms of Actio n of Photopheresis" and ot her related arti cles o n this topic . Several potent ial treatment modal ity could be derived from th is concept if more laboratory and clinical data support this motion , which include : (1) ozone therapy ( w it hdraw about SO ml -100 ml blood from patie nt in transfusion bag, mix ing with small amount of ozone ex vivo and re-infuse back to pat ient in 30 minutes); (2) Cupping therapy (medically ind uced subcutaneous hemorrhage by heat and vacuums effec ts) to expose self ant igens to the abundant dendrit ic cells in the subcutaneous tissue in order to reinforce the self ant igen tolerance . The best t iming for these interventions in theory would be at the NIH-001986 period of fever, viremia stage. These simple approaches can be incorporated with the other medical treatments and support ive care. I cannot be certain, but want to help as a holistic physician. Thank you very much for reading this email and providing your insight as well as help. Sincerely, Ching Y. Voss, M.D. NIH-001987 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 20:10:11 +0000 Conrad, Patricia (NIH/NIAID) [El RE: Invitat ion to Speak at US-Asia Institute Event: February 26, Washington DC Sorry. Cannot do. Congressional Hearin g. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 ) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Zev Moses Date: Monday, February 10, 2020 2:21 PM To: Oplinger, Anne (NIH/NIAID) [E) CbH6)>;Fauci, Anthony (NIH/N IAID) [E) CbH ; Conrad, Patricia (NIH/NIAID) [El (b)(6) Subject: Invitation to Speak at US-Asia Institute Event: February 26, Washington DC -------~~ -------- Good afternoon, The US-Asia Institute would like to formally invite Director Dr. Anthony Fauci to speak at an event on February 26 in Rayburn House Office Building, Room 2253, at 1:00 pm. Our fo rmal invitation is attached. This event will focus on the public health impacts of the novel coronavirus, the facts on the ground, trajectory of the virus, and work to contain the outbreak. The event aims to educate Congressional staff on these topics and to dispel rumors associated with the virus . We believe that Director Dr. Fauci's curr ent research is vital to support ing productive and informative dialogue. Please let us know if Director Dr. Fauci, or another NIAID representative, is available to participate in this event. We would be honored to host him or others from NIAID and our audience would be extremely interested to learn from your agency's research. Sincerely, Zev Moses NIH-001988 Zev Moses I Director , International & Government Affairs US-Asia Institute 232 East Cap itol St. NE Washington , D.C. 20003 202-544-3181 www .usasiainstitute.org NIH-001989 From: Date: To: Subject: Washington, D.C. Atta chm ents: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 19:19:42 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Invitation to Speak at the March 13-15 Trilateral Commission Meeting in Dr. Anthony Fauci - Trilateral Plenary Meeting Speaking lnvitation.pdf Let us di scuss. We do not need t o bring befo re th e OD AM grou p. I wo uld like to do t his if possible. It is an invitat ion f ro m Meghan O'Sullivan w ho was one of th e secur ity crew fr om Bush 43. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Richard Fontaine Date: Monday, February 10, 2020 11:30 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b =)'""' (6) => Cc: Meghan O'Sullivan (b)(6) Torrey Taussig Subject: Invitation to Speak at the March 13-15 Trilateral Comm ission Meeting in Washington, D.C. Dear Dr. Fauci, The Trilateral Commission will hold its invitation-only annual plenary meeting in Washington, D.C., on March 13-15, 2020. I would like to invite you to participate in a conversation at the meeting on responding to the coronavirus and global pandemics . As you may know, the Trilateral Commission was launched by David Rockefeller in 1973 to think through the shared challenges and leadership responsibi lities of the three principal industrialized democratic areas of the world: Europe, North American, and Japan (now Asia). Today, the Commission believes its original mission of bring ing democrat ic countries together to tackle international challenges should once again be a majo r priority for our country and our partners . This year's plenary meeting is a major, three day gathering of our global membership during which we will explore the theme "Democracy and Capitalism at a Crossroads." NIH-001990 Your participation would make a great difference if you are available. Attached to this email you will find an invitation from North American chair Meghan O'Sullivan. Please do let us know if you have any questions about the event or your potential role in it, and we hope that you are able to accept our invitation . Best wishes, Richard Richard Fontaine Executive Director Trilatera l Commission - North America NIH-001991 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:52:31 +0000 Strauss, Eric M. Conrad, Patricia (NIH/NIAID) [El RE: Heat kills novel Coronavirus Eric: The following is all on background. Coronaviruses in general tend to circulate and infe ct predominantly in the winter season {Northern and Southern hemispheres have opposite seasons) . We do not know for sure why th is is t he case; however , many believe that the enclosed spaces in winter {mostly indoor because it is cold) allows better spread of a respiratory borne virus. Also, some viruses tend to thrive in cold, dry weather as opposed to warm, mo ist weather. Remember, however, that when it is summer here , it is winter in Australia and Argentina . This may be the genesis of the information given to President Xi and President Trump that the virus may "go away" in the warm weather. However , this is a brand new virus with which we have no pr ior experience and it is entirely conceivable that seasonal changes will not have any impact on the spread. Hope t hat this is helpful. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 Nationa l Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6] The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended rec ipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Strauss, Eric M. Date: Monday , February 10, 2020 12:27 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Subject: Heat ki lls novel Coronavirus (b)(6)> NIH-001992 Dr. Fauci: We've been seeing a lot about people saying the heat will kill the novel coronavirus? Is this medically sound? Trump discussed Coronavirus briefly: He said he had a long talk with President Xi two nights ago, and the Chinese president told him "the heat generally kills this kind of virus." The president claimed the virus will go away in Apr il as the seasons change: "The virus that we're talking about having to do a lot of people. We think that goes away in April with the heat," he said. Eric M. Strauss, ABC News Managing Editor, Medical Unit www.ericmstrauss .com Phone: 212 -456 -2016 Connect on Social: T/1/F = @ericMstrauss NIH-001993 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 18:08:29 +0000 Jon LaPook FW: "Coronavirus is airbo rne, Chinese official confi rms" Amoy Gardens and SARS.pdf Jon: Thanks for the note. See attaclunent for our future discussion. Best, Tony Anthony S. Fauci , MD Director Nat ional Institute of Allergy and lnfoctious Diseases Build ing 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional In stitutes of Hca llh Be thesda , MD 20892-2520 Phone: (b)(6) FAX: (30 I) 496-4409 E-mail: (b)(6) The infom1ation in this e-ma il and any of its attachments is confiden tial and may contain sensitive infom1ation . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage de vices. The National Institute of Allergy and Infectious Diseases (NlA lD ) sha ll not accept liability for any statements mad e that are the send er's own and not express ly made on behalf of the NIAID by one of its represe ntatives. -----Orig ina l Message----From: Jon LaPook ,.::;....---~ (b ~)~(6) => Date: Monday , febrnary 10, 2020 10:08 AM To: Fau ci, Anthony (NlH/NIAID) [E) (b)(6) > Cc: amb @cbsnews.com ; Kev in Finnegan ; Alturo Rhymes ; Jay Shaylor ; CBS LaPook Subject: "Coro naviru s is airborne , Chi nese official confirm s" ------~-= H i To ny, I need a Fauci brain dump. You may have seen this: https :/fwww .nzherald .co .nz/wor ld/news /article.cfm?c id=2&objecti d= 12307276 Is this news? Don' t we already know that the virus spread via droplet tran sm issio n? Thi s article says aerosol transmissio n means "it can float a long distanc e to the air and cause infection later when it is breathed in." Tha t makes it so und like the kind of spread that happ ens with measles, where the v irus can linger in a room and infect some body 2 hours after some body with mea sles lea ves the room. Tomorrow, I wi ll be giving an hour an d a half of affiliate debriefings on this virus. So we wi ll be reaching mill ions of people. I'd love to get the latest and greatest public health mes sage . Incidentally, Howard Zucker and the infect ious disease folks at NYU Langone are very concerned about overloading our emergency rooms with pat ients wh o have upper respiratory infection symptoms. What is the right message? If somebody calls thinking they have coronavirus , do you tell them to come in - risking infection of othe rs? Do they stay home and wait for symptoms to get wo rse? Of course , it would be grea t if you could send them a kit and happen to home testing . But that 's nowhere in the n ear future , right ? NIH-001998 Thanks, Jon Jonathan LaPook, M.D. Chief Medical Corresponde nt, CBS News Professor of Medicine NYU Langone Hea lth Twitt er @DrLaPook NIH-001999 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 10 Feb 2020 12:54:14 +0000 Sciutto, Jim RE: Long time, no see! Jim: Thanks for the note . All is well here except that I am not getting much sleep - coronavirus 24/7. I look forward to being on your show. Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made t hat are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sciutto, Jim Date: Monday, February 10, 2020 7:43 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Long time, no see! ------~= -------- (b)( > Glad to have you on the show today. Looking forward. Hope all is well. Jim Jim Sciutto Newsroom Anchor & Chief National Security Correspondent CNN Email: jim.sciut to@cnn.com Mobile : ___ (b)( 6Y Twitter: @jimsciutto NIH-002002 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon, 10 Feb 2020 11:18:00 +0000 Conrad, Patricia (NIH/NIAID) [E) Awwad, David (NIH/NIAID) [CJ FW: REQUESTFORA TV INTERVIEW ON WION TV INDIA We did this before, but we cannot do it at 7:30 AM (b)(6) If they want t o do it later in the day and we can fit them in, th en fine. If not, tha t is OK too. Not the highest prior ity From: Lati ka Chugh {WION) Date: Monday, February 10, 2020 6:05 AM ------~~ To: Awwad, David (NIH/NIAID) [CJ (b)(6)>; Fauci, Anthony (NIH/ NIAID) [El (b)(6) >; Fauci, Anthony (NIH/NIAID) [El (b)(6)> Cc: Conrad, Patricia (NIH/NIAID) [El ; Barasch, Kimbe rly (NIH/NIAID) [CJ (b)(6)>; Oplinger, Anne {NIH/N IAI D) [E] (b)(6); Richa Sharma ------- --------N) Subject: REQUEST FORA TV INTERV IEW ON WION TV INDIA Dear Anthony S. Fauci , M.D., NIAJD Director Greetings from WION! I wou ld like to request for your time for an interv iew w ith us today for 10-15 minutes at 7:30 am Monday, in Maryland , USA via Skype . It's regarding the upd ate in the story of Coronavirus -The World Health Organization chief says there have been 'c oncerning instances' of onward transmission of coronavirus among people who hadn't been to China. Waiting for your confirma tion. CLICK HERE TO WATCH WIO N LIVE : NIH-002003 https://www.wion ews.com/live-tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An EsselGroup Company),All rights reserved. www.wionews.com Look forward hearing from you . Regards Latika Chugh WION TV , India (b) (6)> From: Awwad, David (NIH/NIAID) [CJ Date: Thursday, February 6, 2020 6:41 PM To: Latika Chugh {WION) ; KUMAR SUNNY < KUM AR.SUNNY@zeemedia.esselgroup .com > Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger, Anne (NIH/NIAID) [E] Cb)( >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA --------- 1 ---------- Our pleasure. Thank you again . David David Awwad, Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Federal , LLC Phone : (b) (6) (b)(6) Disclai mer : NIH-002004 The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases shall not accept liab il ity fo r any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 8:06 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)(6)>; Barasch, Kimber ly {NIH/NIAID ) [CJ (b)( >; Oplinger, Anne {NIH/NIAID) [E] (b)( >; Richa Sharma (WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~~ ---------David, Many thanks for the Interview. He really added value in our show. We look forward to have his presence in future on WION. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [C] (b)(6) Date: Thursday, February 6, 2020 5:00 PM To: Latika Chugh {WION) ; KUMAR SUNNY Cc: Conrad, Patricia {NIH/NIAID) [E] (b)( .>; Barasch, Kimberly (NIH/NIAID ) [CJ ..... (b)(6) ; Oplinger, Anne {NIH/NIAID) (E] (b)( 1 >; Richa Sharma {WION) Subject: RE: REQUESTFORA TV INTERVIEW ON WION TV INDIA _________ Thank you much. From: Latika Chugh {WION) Date: Thursday, February 6, 2020 6:29 AM To: Awwad, David (NIH/NIAID) [CJ (b)( >; KUMAR SUNNY Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Barasch, Kimberly (NIH/NIAID ) [CJ (b)(6) ; Oplinger , Anne (NIH/NIAID) [E] CbH6); Richa Sharma {WION) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA -------~ = ---------- NIH-002005 Dear David, It will be live Interview on WION with Dr. Fauci at 7 am Maryland Time for 10 -15 m inutes only on Skype. My colleague Mr. Sunny (marked in email) will patch the Skype sharp in 30 minutes from now. Also, We have send you Skype Request from WION Skype Id some hours ago. I request you to please add us. Regards Latika Chugh From: Awwad, David (NIH/NIAID) [CJ Cb)( Date: Thursday, February 6, 2020 4:54 PM To: Latika Chugh (WION) Cc: Conrad, Patricia {NIH/NIAID) [El (b)(6)>; Barasch, Kimberly (NIH/NIAID ) (Cl (b)(6) ; Oplinger, Anne (NIH/NIAID) [EJ (b)(6)> Subject: RE: REQUESTFORA TV INTERVIEWON WION TV INDIA ---------- Let me know if you would like to connect a couple minutes earlier. I am on standby . David ----- (b)(6) (cell) David Awwad , Contractor Customer Services Branch, NIH\NIAID\OCICB NTT DATA Services Fede ral, LLC Phone : Cb)(6) (b)(6) Disclaimer: The information in this e-mail and any of i ts attachments is confidential and may conta in sensitive informa t ion. It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseasesshall not accept liability for any statements made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Latika Chugh (WION) Date: Wednesday, February 5, 2020 9:25 AM To: Awwad, David (NIH/NIAID) [CJ Cc: Conrad, Patricia (NIH/NIAID) [El _________ ; Barasch, Kimberly (NIH/NIAID ) [CJ -------oc-c- = ".":=:=======~ ~ NIH-002006 Cb)( ,> ; Oplinger, Anne (NIH/NIAID) [E] ----------------Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA (b)(6) Thanks See you tomorrow Latika : ------ (b)(6) Get Outlook for And roid From: Awwad, David (N IH/NIAID) [C] Date: Wednesday, February 5, 2020 7:50 :26 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( ; Barasch, Kimber ly (NIH/NIAID ) ________ Cb _H_6J; Oplinger, Anne (NIH/NIAID) [E] (b)(6) Subject: Re: REQUESTFORA TV INTERVIEWON WION TV INDIA Skype Handle: Live:niaidithelp or niaidit help@outlook.com David: (b)(6) Sent from my iPhone On Feb 5, 2020, at 9:16 AM, Latika Chugh (WION) wrote: Yes, It completely fine w ith us. Our Skype Id - wion record. Please share your Skype id with us. We will be online at 7 AM ET TIME WHICH WILL BE 5:3 0 PM OUR TIME IN 1ST. Regards Latika Chugh Producer , Wion India From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 7:35 PM --------- (b)(6) To: Latika Chugh (WION) Cc: Barasch, Kimber ly (NIH/NIAID ) [C] (b)(6)>; Awwad, David NIH-002007 [CJ (NIH/NIAID) [C) __;..;:_;.::::=:,;: (b::::: )(c= 6)::> ____ ,,;__;_ _ (b)(6J>; _ Oplinger, Anne (NIH/NIAID) [E] Subje ct : FW: REQUESTFOR A TV INTERVIEW ON WION TV INDIA Dr. Fauci can do a skype int erview Thu rsday mo rn ing 7 am - 7 :15 am ET by skype. Please let us know asap if that wo rks. Patricia L. Conrad Public Health Ana lyst and Special Assistan t to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Healt h 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: T he info rmation in thi s e-mail and any of its attachments is confidential and may contai n sensitive informat ion. It should not be used by anyone who is not the original inten ded recipient. If you have received this e-mail in erro r plea se inform the sender and delete it from your mailbox or any other storage devices . National Institute of A llergy and Infectious Diseases (NIAID ) shall not accept liabil ity for any stateme nt made that are sender's own and not expressly made on behalf of the NIAID by one of its representat ives. From: Latika Chugh {W ION) Date: Tuesday , February 4, 2020 5:15 AM To: Fauci, Ant hony {NIH/NIAID ) [E] -------=-c-c= (b)(6)> Cc: Wion Guest Relations Subject: REQUEST FOR A TV INTERVIEW ON WION TV INDIA Dear Anthony S. Fauci, M .D., NIAID Director Greet ings from WION! World Is One News (WION)is an internat iona l English news channel from the Zee Media Group, India's premier television brand. WION is un iquely positioned as the 'Globa l Voice of Ind ia', present ing its own perspective on international issues of critical significance. W ION is the prefe rred channel for most op i nion makers across the wor ld as they happi ly attend our shows bringing in credible viewpoints on many issues. WION is currently available in India, Indones ia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia , Singapore and South Africa etc . NIH-002008 WION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your time for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you to join us via Skype. Wa it ing for your confirmation. CLICKHERE TO WATCH WION LIVE : https://www .wionews.com/live -tv Live TV, News I wionews.com © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved. www .wionews .com Look forward hearing from you . Regards L atik a Chu gh WION TV , India Zee Disclaimer: Confidentia lity/ Proprietary Note: This commun ication is confidentia l /proprietary and is intended for use only by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with , th is commun ication NIH-002009 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 10 Feb 2020 00:49:33 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Interview CONFIRMATION: Dr. Anthony Fauci Thanks. From: Conrad, Patricia (NIH/NIAID) [E) (b)(6) Se nt: Sunday, February 9, 2020 7:46 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Interview CONFIRMATION: Dr. Anthony Fauci Sent from my iPhone Begin forwarded message: From: "Griffin, Janelle" Date: February 9, 2020 at 5:54:23 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6) Cc: "Stover, Kathy (NIH/NIAID) [El" (b)(6) , "Routh, Jennifer (NIH/NIAID) [El" (b)(6), "Akinso, Woleo la (NIH/OD) [El" (b)(6), --------~~ "Greene, Nyja " Subject: CNN Inte rview CONFIRMA TION : Dr. Ant hony Fauci Hello, We're all set for tomorrow! Q Dr. Fauc i is confirmed for a live seg ment at 10: I Sa et on Newsroom w/Poppy Harlow & Jim Sciutto. Please ensure he ' s seate d no later than 10:0Sa et. (the show is aware that Dr. Fauci has a hard at 10:20a et) Nyja Greene , cc' d on this email , will be your Atlanta based show point of contact tomorrow. Any issues or changes please don 't hesitate to reach out to her in the morning. Mo11day's segmen t will focus on latest Coronav irus deve lopments: Dr. Fauci covered the SARS outbreak almost 17 years ago- from wbat he's seeing now with the Coronavirus, how bad do think this could become? How does the Coronavirus comp are/contrast with others like Ebola or Zika? How effective are quarantine s in situatio ns like this? What, if any, precautions shou ld we be taking right now in America? Any thoughts /talking points you can send ove.r from Dr. Fauci evening would be super helpful. NIH-002010 Patrici a- thank you sooo much for all of your help with organizin g. We really appreciate it and look forward to Dr. Fauci jo ining the show . From: Conrad, Patricia (NIH/NIAID) [E] CbH > Date: Saturday, February 8, 2020 1:04 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIAID) [El (b) ( >; Routh, Jennifer (NIH/N IAID) [El (b)(6) Akinso, Woleola (NIH/OD) [El (b)(6b Subject: Re: CNN Interview Request: Dr. Anthony Fauci --------Ok thx Sent from my iPhone On Feb 8, 2020, at 12:54 PM, Griffin, Janelle wrote: Great- thank you! Let's keep things for a segment at 10:lSa on Monday . I'll be back in touch after my 6p show planning conferen ce call Sunday evening. Thank so much Patricia Q (b)(6) From: Conrad, Patricia (NIH/NIAID) [El Date: Saturday, February 8, 2020 12:53 PM To: Griffin, Janelle Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Akinso, Woleola (NIH/OD) [E] --------- ,,;_ ___ ;_;_.;..::::~ (b?H;;;;->------ Subject: Re: CNN Interview Request: Dr. Anthony Fauci We can make the 9 am hour wo rk too. Pis let us know ASAP so I can make sure our studio is available. When wi ll you have a final answer? My cell is ____ Cb> _C6) _ and am always on email which is better for me . Sent from my iPhone NIH-002011 On Feb 8, 2020, at 12:48 PM, Griffin, Janelle wrote: That's great- thanks Patricia ! We'll add him to our calendar for 10:lSa et. If we needed to move him his segment to the 9a et hour would that also work? May I have your cell number for my records? From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: Saturday, February 8, 2020 12:46 PM To: Griffin, Janelle Subject: Fwd: CNNInterv iew Request: Dr. Anthony Fauci Hi Janelle We can make this work - it would need to be from between 10 am - 1020 am hard stop. Will that work? It wou ld need to be from our NIH Readycam studio with Videol ink Let me know if that works From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: CNNInterview Request: Dr. Anthony NIH-002012 Fauci Importance: High Good morning Dr . Fauci , I hope this email finds you doing well . I'm reaching out on behalf of Newsroom w/Poppy Harlow & Jim Sciutto hoping you can join for an interview . Are you available to joi n CNN this M onday Febmary lOth in the 10a et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirns. Please feel free to contact me via email or at (404) 452- 7769 to let me know. Thanks for your time - I look fo1ward to hearing from you soo n. Janelle Griffin-Butts Editorial Producer, CNN Email: janelle .griffin@turner.com @janellegCNN NIH-002013 I Twitter: (b)(6) From: Date: To: Subject: Sun, 9 Feb 2020 16:36:38 -0500 autotell I Re: Help Re: Novel Rx for Coronavirus Thanks, Andy. Best regards, Tony On Feb 9, 2020, at 4:29 PM, autotelll ----------- CbH wrote: Thank you my friend, hope it leads to something good for patients and the public . I was at a meeting of the "Philosophical Societ y of Texas" this week end and meet with a lot of Bush alums like Don Evans and Margaret Spellings etc and Margaret was commenting on the coronavirus scare and how fortunate we are to have you there at NIH looking after us!! If you ever decide to relocate to Texas you have a fan club here! All my best Andy -------- From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 7 :24 AM To: autotell I Cb)C > (b)( > Subje ct: RE: Help Re: Novel Rx for Coronav irus Andy: Thanks for the note. I wi ll take a look at this and more important ly, I wil l run it by the peop le here at NIAID who are r unning the nCoV research initiative. I will get back to you with their and my assessment. I hope that all is well with you. We are doing a lot of late nighters here . Fee ls like my internship. DD Best regards, Tony From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID} [E] (b)( 6) > Cb)( > ------~= -------- Cc: Xiaokui Zhang (b)(6) (b)(6)>; Fauci, Anthony (NIH/NIAID) [E) >; Robert Hariri (b)(6)> Subject: Help Re: Novel Rx for Coronavirus Tony NIH-0020 19 Greetings . Always proud to see you at the White House (with Alex) leading the fight against th is latest infect io us disease threat (b)( 4) (b) (4) I trust this email finds my Paisano happy and content as you cont inue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family . Hope our paths cross soon Andy NIH-002020 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:23:24 +0000 To: Folkers, Greg (NIH/NIAID) [E] Subject: RE: lnvestigational compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus WOW! I did not know tha t. Good talking point for press conferences. From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 1:13 PM Subject: lnvestigat ional compound remdesivir, developed by UAB and NIH researchers, being used for treatment of novel coronavirus lnvestigationalcompound remdesivir,developed by UAB and NIH researchers, being used for treatment of novel coronavirus by Savanna h Koplon • February 07, 2020 • Print • Email ___ --- ,Richard Whitley, M .0 ., Distinguished Professor at UAB and principal investigator of the U19 grant The investigationa l drug remdesivir, developed through research cond ucted through the Ant iviral Drug Discovery and Developm ent Cent er, or AD3C, and centered at the University of Alabama at Birm ingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of nove l coronavirus (2019-nCoV). UAB was awarded a $37.5 million, five-year U19 grant from the Nati onal Inst it ute of Allergy and Infectio us Diseases Centers of Excelle nce fo r Translat ional Research to study and develop treatment for high-priority emerging infections. Work has been taking place in earnest to develop drugs for emerging influenza, flaviviruses (dengue, West Nile virus and Zika), coronaviruses that cause SARSand MERS,and alphaviruses such as Venezuelan equine encephalitis virus and chikungunya. The grant is a multi - NIH-002021 institutional collaboration to accelerate drug discovery for these emerg ing infections and is a publicpr ivate partnership between academic institutions and Gilead Sciences. Remdesivir, developed to treat the coronavirus causing MERS,was found to have significant activ ity against the 2019-nCoV strain when the outbreak began in the Chinese city of Wuhan. Importantly, remdesivir had demonstrated efficacy in treating other medically important coronav iruses MERS and SARSin cell culture and animal models . Based on the compassionate plea requests of treating physicians in the United States, Gilead Sciences released remdesivir for use in a few patients, although the drug has not yet been tested for safety or efficacy in these diseases. "The release of remdesiv ir for safety and efficacy studies is a major accompl ishment for the AD3C - namely the U19 grant - as it shows significant and swift advance of antiv iral drugs to help treat and respond to emerging infectious disease outbreaks on an international scale and, importantly, to anticipate the introduction of these infections in the United States," said Richard Whitley , M.D., Distinguished Professor at UAB and princ ipal investigator of the U19 grant. WATCH: UAB inf ect ious disease expert s prov ide info rmat ion on the 2019 novel coronav irus. Gilead Sciences and supporting researchers and clinicians are working with health authorities from the World Health Organization and in China to establish a placebo-controlled study to determine whether remdesivir is safe and effective in treating 2019- nCoV. "This is a prime example of how the research we are conducting at UAB plays a critical role in treating patients on a global scale and our contribution of substantial scientific advances." - Richard Whitley, M .D., UAB Distinguished Professor "The collaboration between UAB, our colleagues at Southern Research, Vanderbilt University and the University of North Carolina, along with our pharmaceutical partner Gilead Sciences, is indicative of our collaborat ive approach to respond to outbreaks in real time, and in helping commun ities worldwide fight 2019-nCoV. This is a pr ime examp le of how the research we are conducting at UAB plays a critical role in treat ing patients on a global scale and our contribution of substantial scientific advances," Whitley continued . Whitley expressed that the potent ial for mutation of 2019-nCoV means that UAB's AD3C and partners wi ll need to build backup molecules for potential testing and treatment in the near future. The World Health Organization has declared the 2019-nCoV outbreak a "public health emergency of international concern ." UAB is the lead institution for AD3C and research conducted; but the team unifies scientists experienced in virology, viral immunology, pathogenesis, medicinal chemistry and trans lation to human disease from UAB, University of North Carolina, Vanderbilt University, Emory University, Washington University , The University of Texas Medical Branch, Southern Research, the Emory Institute of Drug Discovery, the University of Colorado, Denver, and Oregon Health & Science University. Disclaim er : Any third-party material in this email has been shared for internal use under fai1· use provision s of U.S. copyright law, without further ver ification of its accuracy/veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. gover nment. NIH-002022 From: Date: To: Cc: Subject: Attachme nts: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 18:20:45 +0000 Liz Szabo Conrad, Patricia (NIH/NIAID) [E] RE: Plumbing as possible means of spread of coronaviruses Amoy Gardens and SARS.pdf Liz: Thanks for the note . I do not know enough about the plumbing system on the cruise ships to make any meaningful comments, certain ly not any comments that could be att ributable to me. And so, I will pass on this one, The best person to comment or opine on this would be Mart Cetron of CDC. FYI, in case you do not have it in front of you, I am attaching the original NEJM article on the Amoy Gardens Apartment story in Hong Kong w ith SARS. Best regards, Tony From: Liz Szabo Se nt : Saturday, February 8, 2020 7:21 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Plumbing as possible means of spread of coronaviruses ------ ~~ HI Dr. Fauci, I hope you're doing well. I know you must be very busy. Our editor, Dr. Elizabeth Rosenthal, is wondering whether the new coronavirus might be spreading through plumbing on the cruise ship? She sent me these links, below, about how plumbing played a role in spreading SARS in the Amoy Gardens apa1tment complex in Hong Kong. Libby lived in China during the SA.RSoutbreaks and remembers that the sinks there don't ha ve the typ ical U-bend trap tha t sinks have here, which allows sewer gases and unpleasant odors to come through. If plumbing is a risk for spreading coronavimses, what could be done to protect passengers on cruise ships? T'd love to hea r your thoughts on this, even if just by email. Thanks for your time. Liz Szabo Kaiser Health News 571-201-9009 https://www.cbsnews.com/news/leaky-plumbing-Linked-to-sars-spread/ NIH-002023 https://www .cnn.com/2013/02/21/world/asia/sars -amoy-qardens/ index.htm l https://plumb inqconnection .com.au/new-report -proves-plumbinq-link-to-sars/ https://www .infectioncontro ltoday.com/persona l-protective -equipment/sarsand-plumbing-role-sewage-plays-spreading-disease https:/ /jamanetwork .com/journals / jama /fullarticle /27 61044 ?guestAcces sKey=f 6 l bd430-07 d8-4b 86-a 749bec05bfffb65&utm source=For The Media&utm medium=referral&u tm campaign =ftm links&u tm content=tfl&utm tenn =020720 NIH-002024 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:59:10 +0000 To: Tabak, Lawrence (NIH/OD) [E) Cc: Schwetz, Tara !NIH/OD) [E];Erbelding, Emily (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [El;Marston, Hilary (NIH/NIAID) [El;Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [El;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6)) Subject: RE:NCATsrequest re. Coronavirus Larry : '--------------------------------, (b "'~""' (S) Best, Tony From: Tabak, Lawrence (NIH/OD) [E) Date: Sunday, February 9, 2020 12:46 PM -----~~ To: Fauci, Anthony (NIH/NIAID) [El Cc: Schwetz, Tara (NIH/OD) [El Subject: NCATsrequest re. Coronavirus (b)(6)> --------..;;...;.:...:::====:~=----(b)( > (b)(6) --------- Ton' '-------------------------------~ ~ (b) (5) Thanks, Larry NIH-002025 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:53:04 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci OK. Thanks. From: Conrad, Patricia (NIH/NIAID) [El Se nt: Sunday, February 9, 2020 12:44 PM (b)(6)> To: Fauci, Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Subject: Fwd: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci I am working on this. Sent from my iPhone Begin forwarded message: From: "Varon, Sophie" Date: February 9, 2020 at 12:30:31 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (NIH/NIAID) [El" -------~= (b)(6)>, "Fauci, Anthony (b)(6) Subject: CNN And e rson Cooper Full Circle Request- Dr . Anthony Fauci Hello Dr. Fauci and Patricia , I hope you're both doing well. I'm reach ing out to see if Dr. Fauci could be available for an interview wi th Anderson Cooper on Monday for hi s CNN digit al program, Full Circle . Full Circle is an intere sting platform because it allows us to take live viewer questions . This taped interview would air on Tuesday at 5PM and Anderson cou ld tape tomorrow in the 4PM hour or after 5:45PM. The topic is of course the Corona virus. Thank you for considering this request! Sophie Varon Ed itorial Producer , CNN AC360 cell(bH NIH-002026 From: Date: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:52:22 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: CNN Anderson Cooper Full Circle Request- Dr. Anthony Fauci To: Subject: If we can do this, I w ou ld be happy to. From: Varon, Sophie Date: Sunday, February 9, 2020 12:30 PM To: Conrad, Patricia (NIH/ NIAID) (E] (b)(6) -------~ --------- = (b)(6)>; Fauci, Anthony (NIH/ NIAID) (E] Subject: CNN Ande rson Cooper Full Circle Request - Dr. Anthony Fauci Hello Dr. Fauci and Pa tricia , I hope you're both doi ng wel l. I'm reaching out to see if Dr. Fauci could be ava ilable for an interview wit h Ande rson Coope r on Monday for his CNN digital program, Full Circle. Full Circle is an interes ting platform because it allows us to take live viewer questions. This taped interview would air on Tuesday at 5PM and Anderson could tape tomorrow in the 4PM hour or after 5:45PM . The top ic is of course the Coronavirus. Thank yo u for cons idering this request! Sophie Varon Editorial Producer , CNN AC360 cell (b)(6) NIH-002027 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 9 Feb 202017:5 1:21 +0000 Hall, Bill (HHS/ASPA) FW: CNNI Interview with Dr. Anthony Fauci, Bill: Th is link below is for an interview know, it makes such a big difference that I gave for CNN International when the interviewer this morning . As we all knows the subject and asks good questions that this interviewer did. Would that they were all like her. Best regards, Tony From: Hynds, Joanna (NE) Se nt : Sunday, February 9, 2020 12:30 PM -------'"="'""C=t To: Conrad, Patricia (NIH/NIA ID) [El CbH6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, We are so glad to! Here is the clip https:ljwe .tl/t - BOkVJSyQVB Al I the best, Joanna From: Conrad, Patricia (NIH/NIAID) [El Date: 09 February 2020 16:15 To: Hynds, Joanna (NE) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, --------- (b)(6)> My pleasure- so glad we could make it wor k. Please do send us the the video segment Best, Patty . Sent from my iPhone On Feb 9, 2020, at 11:06 AM, Hynds, Joanna (NE) wrote: Dear Mr Fauci, NIH-002028 I just wanted to thank you for your accommodation at such short not ice for the earlier interview. I do apologise for the miscommunication on my part. We really enjoyed having you on the show! Thanks too to Patricia, for helping coordinate this all at last minute. I hope you both have a great evening. Many thanks again for your patience and understanding. If you would like a video segment of your hit I will gladly send you it on request. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6) Date: 09 February 2020 14:26 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------=-c--=-(b)(6)> -------- Do you have the hit time and contact info please send ASAP. Sent from my iPhone On Feb 9, 2020, at 8:38 AM, Hynds, Joanna (NE) wrote: Perfect - we really appreciate this. I will get you these deta ils ASAP. Does Dr Fauci need a car? Best, Joanna NIH-002029 From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Date: 09 February 2020 13 :33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the studio address and on-site contact name, number and cell number ASAP. Dr Fauci cell is (b)(6)andyou have mine. Thank you . Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Patricia, Just following up from our phone conversation , unfortunately I won't be ab le to facilitate a StudioGo t ruck for this interview. We are still really keen to get Dr Fauci on the show-w ill he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)~ > Date: 09 February 2020 13:00 To: Hynds, Joanna (NE) Subje ct: Re: CNNI Interview Request: Dr. Ant hony Fauci, NIH-002030 For the t rick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia {NIH/NIAID) [El (b)(6)> wrot e: Please call me ASAP at request. ----- (b)(6)for this Sent from my iPho ne Begin forwarded message: From: "Fauci, Anthony (NIH/NIAID) Cb)C > [El" Dat e: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patr icia (NIH/NIAID) [E]" (b)(6) Subject: Fwd: CNNI Int erview Request: Dr. Anthony Fauci, Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: "Fauci, Anthony (NIH/NIAID) [El" (b)(6)> Cc: "Tejera, Isabel {Intern)" , "Lovejoy, Hannah NIH-00203 1 (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronavirus. Might this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia NIH-002032 Pacific region and Latin Americ a. • In September 2019 CNN.com had 162 million unique readers globally per month and 114 mi llion mobile readers a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN Intern ation al + 44 207 693 1640 (office) + (b)(6) ( cell) joanna.hynds@turner.c om Information in t his emai l including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the orig inator . If you have received this email in error, please notify the sender by return email and delete it from your system . You should not reproduce, d istr ibute, store, NIH-002033 retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communicat ion through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence . Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internationa l Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received th is email in error, please not ify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone . Please note we reserve the right to mon itor all e-mail commun ication through our internal and external networks. NIH-002034 Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Mar lborough Street, London W l F 7HS. Informat ion in this email includ ing any attachments may be privileged or confidential and is intended exclusively fo r the addressee. The views expressed may not be officia l policy, but the personal views of the originator . If you have received th is email in error, please notify the sender by return email and delete it from you r system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail comm unication through our interna l and externa l networks . Turne r and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Enterta inment Networks Internationa l Limited (Company No. 28035 12), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turne r House, 16 Great Marlborough Street, London WlF 7HS. Information in th is email including any attachments may be priv ileged or confidentia l and is intended exclusively for the addressee. The views expressed may not be off icial policy, but the personal views of the originator. If you have received th is email in error, please notify the sender by return e-mail and delete it from your system. You should not rep roduce, distr ibute, store , retransm it, use or disclose its contents to anyone. Please note we reserve the right to mon itor all e-mail communicat ion through our internal and externa l netwo rks. Turne r and the Turner marks are trade marks of Turne r Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks Internat ional Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Internat ional Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered off ice at Turner House, 16 Great Marlborough Street, London WlF 7HS. Informat ion in this email includ ing any attachments may be privileged or confident ial and is intended exclusively for the addressee. The views expressed may not be off icial pol icy, but the personal views of the originator . If you have received this email in error, please not ify the sender by return e-mail and NIH-002035 delete it from your system . You should not reproduce, distribute, store, retransmit , use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002036 From: To: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 17:34:16 +0000 Denise Ober Subject: RE: HEART WRENCHINGQUESTION! Will Date: The State Department and CDC travel alerts for China, which advise only absolutely essential travel, do not officially include Hong Kong and so there is no official restriction right now (but this could change), and there is no quarantin e requir ement upon returning from Hong Kong. However , thi:; all could chang e quickly . (b)(6) -----Original Mes sage ----From: Denise Ober ;;-- ------(b ~)~(=6) Date: Saturday , February 8, 2020 3:23 PM -------:,,:,~ -------- To: Fauci, Anthony (NIH/NIAJD)[E] Subject: HEART WRENCHING QUESTION1 WO (b)(6) > Dear Dr. Fauci, l realize this is a long shot for you to answer this email. Please forgive me since Im sure you are so extremely busy and so very importantly needed at this time. I do apologize for taking even a moment from your high demand schedule. But thought I'd try to reach out anywayin case you did see this. l saw an interview recently you bad with Dr Baucher posted by JAMA. From your expertise and knowledge about the coronavirus thus far if ou had lannedto travel to Thailand mid March via stop over at Hon Kono-would ou? (b)(6) Thank you from my concerned heart! Thank you for EVERYTHINGyou do and have done in the past! Best to you, Denise Ober Sent from my iPad NIH-002037 From: Date: Fauci, Anthony (NIH/NIAID) [El Sun, 9 Feb 2020 17:26:01 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Cc: Conrad, Patricia (NIH/NIAID) [E);Erbeld ing, Emily (NIH/NIAID) [E];Auchincloss, Hugh (NIH/NIAID) [C] (b)(6) ;Barasch, Kimberly (NIH/N IAID) [C];Greg Folkers (b)(6J;Marston, Hilary (NIH/NIAID) [E);Eisinger, Robert (NIH/NIAID) [E];Lerner, Andre a (NIH/NIAID) [E] Subject: FW: Help Re: Novel Rx for Coronavirus __ Cb _>_C4 _) in 2019-CoV Proposal 07Feb2020.docx Attachments: --------- Cristina : This is not jus t your ordinary person writing to us. Th is is Dr. Andrew von Eschenbach, former Director of NCI and Former Commissioner of FDA. I have no idea if this proposal has any merit; however, please have someone go over it carefully and put together a response. Also, only if appropriate, and feasible, see if there is any way we can be of assistance to him. Best regards, Tony ----------------~~ From: autotell I Date: Friday, February 7, 2020 2:50 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) Cc: Xiaokui Zhang (b)( 6) Th anks. (b)(6) -------- _____ ....::.===~~------ (b) (6) >; (b)( >; Fauci, Anthony (NIH/NIAID) [E] Robert Hariri ---------- (b)(6) Subject: Help Re: Novel Rx for Coronavirus Tony Greet ings. Always proud to see you at the Wh ite House (with Alex) leading the fight against this latest infect ious disease threat. Cb)(4) (b) (4) I trust this email finds my Paisano happy and content as you continue to be a gift to this nation and the world. Please let me know you received this email. My best to you and your family. Hope our paths cross soon Andy NIH-002038 From: Date: To: Cc: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 202017:17:07 +0000 Stover, Kathy (NIH/N IAID) [El Billet, Courtney (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Folkers, Greg (NIH/NIAID) [El Subject: RE: FORASF REVIEW:Draft responses to questions from Italian news agency See my edits in red. From: Stover, Kathy (NIH/NIAID) [E] (b)(6)> Date: Friday, February 7, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [El-----(b =)'""' (6) => Cc: Billet, Courtney (NIH/N IAID) [El (b)(6),; Conrad, Patricia (NIH/NIA ID) [E) (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: FORASF REVIEW:Draft responses to questi ons from It alian news agency ---------Hi Dr. Fauci, Below are draft responses t o questions from a reporter with the Italian news agency ANSA. Please let me know if you have any suggested edits, and I'll move it along. Thanks, Kathy Enrica Battifoglia Science and Technology Head Editor ANSA news agency (Italian news) Enrica .Batt ifogl ia@ansa .it Expected place of publication: ANSA Science web page (www .ansa.it/scienza ) Dear Professor Fauci , I am Enrica Battifoglia of the Italian news agency ANSA, I already have had the ple asure to interview you several times at the AIDS world conferences. I would like to ask you some questions about Coronavirus 2019-nCoV, to be published on the ANSA Science web page (www .ansa.it/scienza ), the main online science news resource in Italy with over 1.5M contacts each month. I am sure that your clarity and competence will be highly valuable to put some much-needed order among so many contrasting news and data, and would be much appreciat ed by our readers . NIH-002039 1. Do the current available data allow to understand the threat level of coronavirus 2019nCoV in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? There is much that we do not know about the novel coronav irus. Curre ntly, there have been more than 37,000 confirmed cases in China, and China has reported more than 800 deaths. As you know, there have been three confirmed cases in Italy to date. The reported case fatality rate (lethality) among the 37,000 cases that have come to the attention of the health care system is 2%. However , given that there are likely many more cases that are without symptoms or with minimal symptoms, the actual death rate is probably lower than 2%. It is impossible to predict how the virus will evolve. It is our hope that the extraordinary containment measures that China has implemented will help prevent the outbreak from becoming a global pandemic. But given that the virus is present in 27 countr ies to date and can be transmitted from person-to-person, it may take a footho ld and evolve into a global pandemic . 2) What exactly do we know about its modes of transmission, especially from people who do not yet have the symptoms? Again, there is much that we do not know about the novel coronavirus, including its specific transmission abilities. Based on initial findings that have been reported, we suspect its transmission is similar to influenza and other respiratory viruses, namely that is transm itted through respiratory droplets when an infected person coughs or sneezes, and by touching surfaces, such as door handles, that recently have virus on them and then touching your face. There have also been reports that the virus is present in feces and vomit. However, it is still uncertain that the virus can be transmitted through this route. Traditionally, most viruses are transmitted when someone has symptoms. With the novel coronavirus; however, there appears to be asymptomatic transmission occurring. We do not know how many cases are being driven by asym ptomatic transm ission or by those with symptoms . Typ ically, viruses are largely transmitted by infected peop le experiencing symptoms. 3) Are the genetic sequences provided by China enough to start working on a vaccine? The genet ic sequences provided by Chin a enabled researchers to quickly deve lop a diagnostic that is being used to dete1mine whether someone is infected with the novel coronavirus. The genetic information has also been useful in work to develop a preventive vaccine. The National Inst itute of Allergy and Infectious Diseases, part of the U.S. Natio nal Institutes of Health, is building on its experience with the SARS and MERS corona viruses to better understand the virus as well as develop and test rapid point-of-care diagnostics , vaccines and treatments, including broad-spectrum antivirals and antibody therapies. In terms of vaccines specifically , we are NIH-002040 working with the biotechnolog y company Moderna and the Coalition for Epidemic Prep aredness Innovation (CEPI) to develop a "messenger RNA" vacci ne for the novel coronav irus. Other countries and companies are working to develop a vaccine as well. 4) What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? In terms of our work with Moderna and CEPI to develop a vaccine , we anticipate having an experimental vaccine ready for Phase 1 clinical trials within 2 to 3 months. This Phase 1 clinical trial will involve administering the vaccine to a sma ll number of healthy adults in the United States to see if it is safe and has some ability to induce an immun e response. If that is successful and the outbreak has not ended, we will move to a larger Phase 2 clinical trial with the expectation of proving the efficacy (or not) of the vaccine within 1 to 1.5 years. If efficacious, it will still take additional months to produce enough vaccine to distribute widely .. In addition to this vaccine, NIAID is also supporting scientists and companies to develop other vaccine candidates. 5) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk of repetition of these events? To clarify, the 2009 HlNl influenza virus was first reported in Mexico, not China. Viruses affecting humans have occurred throughout history, from the Bubonic Plague to the 1918 flu. We cannot predict what emerging infectious diseases will occur nor prevent the unknown from occurring in the first place. What we can do is learn as much as we can about emerging viruses, so that we can rapidly develop safe and effective point-of-care diagnostics, treatments and vaccines to protect against infection. NIH-002041 From: Fauci,Anthony (NIH/NIAIO) [E) Date: Sun, 9 Feb2020 16:41:33 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: FW: Cowen Health Care Conference in Boston - China Pharma Market Panel March 2, 2020 in Boston Please RSVPno. From: Scala,Steve Se nt: Sunday, February 9, 2020 11:39 AM To: Fauci,Anthony (NIH/NIAID) [El (b)(6) Cc: Nadeau, Phil ;Miner, Kathy ; Nedelcovych, Michael Subject: Cowen Health Care Conference in Boston - China Pharma Market Panel - March 2, 2020 in Boston ------~~ -------- Hi Dr. Fauci I am a pharmaceutical industry analyst at Cowen and Company, a New York City based investment company that specializes in health care. Each year we host a Health Care Conference in Boston in March that attracts 200+ companies and 1000+ investors. During this year's conference, we had planned to host a one-hour panel discussion on the evolution of and reforms within the China Health Care System and China Pharmaceutical market. However, given global concerns around Coronavirus, we have decided to focus the panel instead on the virus and the outlook for emerging treatments. This perspective is critical to health care companies and therefore the institutions that invest in them. Our panel will take place during Cowen ' s 40th Annual Health Care Conference, which will be held at the Marriott Copley Place in Boston on March 2-4, 2020. We plan to host this panel on Monday morning, March 2 nd, between 9:05-10:0SAM. Attendees at our conference include institutional investors from insurance companies, mutual funds, pension funds, banks, and other types of funds, mainly in the U.S. and EU. Cowen would provide you an honorarium for your time during the one-hour panel. We propose an honorarium of $1,500, and we reimburse conference-related travel expenses. The discussion will be Q&A only and no presentation on your part is requested . We look forward to hearing from you. Sincerely, Steve Scala NIH-002042 In line with best practices suggested for brokerage firms, Cowen has a policy regarding our interaction with subject matter experts such as yourself, and by accepting and participating in this engagement, you agree to the conditions of this policy, including that you will not knowingly disclose any material non-public and/or confidential information; that your current employer permits you to participate in our event; that you are not employed by any of the companies anticipated to be discussed; and that your participation will not cause you to knowingly violate any contract (e.g., employment contract or consulting contract), agreement (e.g., confidentiality agreement) or other duty of confidentiality (e.g., serving on a board of directors) that you may have. COWEN Steve Scala Pharmaceut ical Industry Analyst Equity Research Cowen and Company , LLC Two Internat ional Place , 28th Fl. Boston , MA 02110 617-946-3923 steve.sca la@cowen.com www .cowen.com This message and any attachments are confident ial. If you are not the intended recipient, please notif y t he sender immediately and destroy this email. Any unauthor ized use or dissemination is prohibited. All email sent to or from our system is subject to review and ret ention . Nothing contained in this email shall be considered an offer or solicit ation with respect to the purchase or sale of any securit y in any jurisdiction where such an offer or solicitation would be illegal. Neither Cowen Inc. nor any of its affiliates ("Cowen") represent that any of the information contained herein is accurate, complete or up to date, nor shall Cowen have any responsibility to update any opinions or other information contained herein . NIH-002043 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 16:41:04 +0000 Folkers, Greg (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] RE: Podcast: Newt's World Ep 56: China's Coronavi rus http;//bit.ly/2Sud2am Definitely for the Director's page From: Folkers, Greg (NIH/N IA ID) [E) (b)(6) Se nt: Sunday, February 9, 2020 9:45 AM Subject: Podcast: Newt's World Ep 56: China's Coronavirus http://bit .ly/2Sud2am Is the Coronavirus the next global pandemic or will the disease be eradicated in a short period of time? Newt's guests, Dr. Anthony Fauci and Dr. Peter Daszak, provide the information you need to know about the Coronavirus crisis. Disclaimer : Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without furth er verifica tion of its accuracy/veracity . It does not necessa rily repre sent my views nor those of NIAJD, NIB , HHS , or the U.S. government. NIH-002044 From: Date: (b)(6) To: Cc: Subject: Sun, 9 Feb 2020 10:53:02 -0500 Conrad, Patricia (NIH/NIAID) [El Billet, Courtney (NIH/NIAID) [El;Routh, Jennifer (NIH/NIAID) [El Fwd: CNNI Interview Request: Dr. Anthony Fauci, Done Begin fo1warded message: From: "Hynds,Joanna (NE)" Date: February 9, 2020 at 9:49:2 1 AM EST -----------=~ To: "Conrad , Patricia (NIH/NIAlD) [E]" CbH6) Cc: "Pfeifer, Hazel" , "Lovejoy , Hannah (NE)" , "Fauci, Antho ny (NIH/N IAID) [E]" (b)(6) > Subject: RE: CNNI Interview Request: Dr. Anthony Fauci, Hi Patricia, I have let DC know, Angie will be there to greet him at 10.20a and bring him straight up . DC Number: + l 2025100172 . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [El (b)(6)> Date: 09 February 2020 14:42 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [El ------"-="'""C"-='I (b)(6J> Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, -------- We are good . 1030 am ET his is firm . He will arrive the wdc cnn studio at 820 am ETso if you can have someone meet him at the entrance lobby to get him upstairs quickly that would be helpful. Sent from my iPhone NIH-002045 On Feb 9, 2020, at 9:39 AM, Hynds, Joanna (NE) wr ote : Hi Pat ricia, That would be perfect. I am so sorry on the miscommun icat ion on my part. We really appreciate you accommodating us at this short notice . Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 14:35 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Re: CNNI Interview Request: Dr. Anthony Fauci, Dr DrFauci can be there for a 1030 am hit We need to know ASAP if this is firm and what the exact hit time Sent from my iPhone On Feb 9, 2020, at 9:26 AM, Hynds, Joanna (NE) wrot e : Just wanted to let you know the Flash Studio will be DC G Studio CAM23 Our Bureau Address is 820 First ST NE 20002 Washington Please contact the bureau at +1-202-898-7911 NIH-002046 Please arrive at 10.40, you will be on around 11 - 1will update with exact hit time as soon as I have it. Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E) (b)(6)> Se nt: 09 February 2020 13:33 To: Hynds, Joanna (NE) Cc: Pfeifer, Hazel ; Lovejoy, Hannah (NE) ; Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Re: CNNI Interview Request: Dr. Ant hony Fauci, Adding Dr Fauci here He can come to the WDC CNN studio. Please send us the exact live hit time as well as the stud io address and on-site contact name, number and cell numbe r ASAP. Dr Fauci cell is (b)( - and you have mine. Thank you. Sent from my iPhone On Feb 9, 2020, at 8:21 AM, Hynds, Joanna (NE) wrote: Dear Pat ricia, Just following up from our phone conversation, unfortunately I won't be able to facilitate a StudioGo truck for this interview . We are still really keen to get Dr Fauci on the show - will he be able to come to the bureau? I will be able to book him a car if he needs. Let me know what suits, NIH-002047 Best, Joanna From: Conrad, Patricia (NIH/NIAID) [E] (b)(6)> Date: 09 February 2020 13:00 To: H ynd~Joanna(NE) Subject: Re: CNNI Interview Request : Dr. Anthony Fauci, For the trick- the location is northwest Washington DC. Near American university. Sent from my iPhone On Feb 9, 2020, at 7:51 AM, Conrad, Patricia (NIH/NIA ID) [E) (b)( >wrote: --------- Please call me ASAP at for this reques t. ----- (b)(6) Sent from my iPhone Begin forwarded message: From: " Fauci, Anthony (N IH/NIAID) [El" (b)(6) Date: February 9, 2020 at 7:08:54 AM EST To: "Conrad, Patricia (N IH/NIAID) [El" • (b)(6) Subject: Fwd : CNNI Interview Request: Dr. Anthony Fauci, NIH-002048 Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Date: February 9, 2020 at 6:06:15 AM EST To: " Fauci, Anthony (NIH/NIAi D) [E]" - (b)(6) ■ Cc: "Tejera, Isabel (Intern)" , "Lovejoy, Hannah (NE)" Subject: CNNI Interview Request: Dr. Anthony Fauci, NIH-002049 Dear Dr Fauci, I hope you are well! I am reaching out from CNN lnternatio nal to enquire if you are available today to jo in us on Connect the World at llaET to discuss the coronavir us. Might this be a possibility ? It would be great to arrange this. Backgroun don CNN • C N N In te rn ati on al re ac he s NIH-002050 m or e th an 25 0 mi Iii on ho us eh ol ds w or Id wi de in cl ud in g in th e u s vi a DI RE CT V. • C N N In te rn ati on al is th e NIH-002051 nu m be r on e int er na ti on al TV ne w s ch an ne ac co rd in g to all m aj or m ed ia SU rv ey s ac ro ss Eu ro pe th e Mi dd NIH-002052 le Ea st an d Af ric a, th e As ia Pa cif ic re gi on an d La tin A m eri ca • In Se pt e m be r 20 19 ~ N N. co m ha d 16 2 mi Iii on NIH-002053 un iq ue re ad er s gl ob all y pe r m on th an d 11 4 mi Iii on m ob ile re ad er s a m on th le ad in g th e BB C, Ya ho 0 an d NIH-002054 N e w Yo rk Ti m es Best, Jo anna Hynds Planning Desk CNN Internati onal + 44 207 693 1640 ( office) (b)(6) ~ (cell) joanna.hy nds@turn er.com lnformatio n in this email including any attachme nts may be priv ileged or confidenti al and is intended exclusive ly for the addressee NIH-002055 . The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return email and delete it from your system . You should not reproduce distribute, store, retransmit , use or disclose its contents to anyone . Please note we reserve the right to monitor all e-mail communic ation through our internal NIH-002056 and external networks. Turner and the Turner marks are trade marks of Turner Broadcasti ng System Inc and are used under licence. Turner Broadcasti ng System Europe Limited (Company No. 1927955), Turner Entertain ment Netwo rks lnternat io nal Limited (Company No. 2803512), Turner Broadcasti ng System Holdings (Europe) Limited (Company Number 2802926) and Cable News lnternat io nal NIH-002057 Limited (Company No. 5001368) are incorporat edin England and Wales and share the same registered office at Turner House, 16 Great Mar lboro ugh Street, London WlF 7HS. Informat ion in this emai l including any attachments may be privileged or conf identia l and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the or iginator. If you have received this email in error , please not ify the sender by return e-mail and delete it from you r system . You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-ma il communication through our internal and external networks . Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turne r Enterta inment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wa les and share the same registered off ice at Turner NIH-002058 House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return email and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error , please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute , store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail NIH-002059 communication through our internal and external networks. Turn er and the Turner marks are trade marks of Turner Broadca sting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Netwo rks International Limited (Company No. 2803512), Turner Broadca sting System Holding s (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London W 1F 7HS . NIH-002060 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 9 Feb 2020 13:05:06 +0000 Kaplan, Edward H To: Cc: Redfield, Robert R. (CDC/OD);Cetron, Marty (CDC/DDI0/NCEZID/0GMQ);Messonnier, Nancy (CDC/DDID/NCIRD/OD) Subject: RE: Coronavirus containment modeling hems_Wuhan_Feb7_2020_1n_Press.pdf Attachment s: Ed: Many thanks for sendj ng the manuscript . I hope that all is well with you. Best regards, Tony -----Original Message----From: Kaplan , Edward H Date: Saturday , February 8, 2020 I 0: 13 PM To: Fauci , Anthony (NTH/NlAID)[E] Subject: Coronavirus containment modeLing -------~~ ------~~ (b) (6) > (b)(6) > Dear Dr. Fauci, It has been many years since we corresponded regarding smallpox bioterrorism and vaccination conlTOI. The attached paper on containing a community coronavirus outbreak from a few initial cases via isolation and quarantine might interest you. The news is mostly good - isolation and quarantine can ge1the transmission rate below epidemic thresho ld - but the key is rapid detection of infect ed persons . Also discussed are some ideas for alleviating congestion in the hospital. I hope that you find it helpful. Best, Ed Kaplan Edward H. Kaplan, Ph .D. William N. and Mar ie A. Beach Professor of Operation s Research Professor of Public Health Professor of Engineering Yale School of Management Box 208200 New H aven, Conne cticut 06520-8 200 Phone: e-mai l: _______ (b)(6) Cb _)_C6) _ http://faculty.som.yale.edu/EdKaplan/ NIH-00206 1 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 12:40:23 +0000 Conrad, Patricia (NIH/NIAID) [El RE: CNNI Interview Request: Dr. Anthony Fauci, I w ill do this and if they can bring a truck to the house like they did last time, it was great. Let us discuss. From: Hynds, Joanna (NE) Se nt : Sunday, February 9, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [El ------ ~= (b)(6) Cc: Tejera, Isabel (Intern) ; Lovejoy, Hannah (NE) Subject: CNNI Interview Request: Dr. Anthony Fauci, Dear Dr Fauci, I hope you are well! I am reaching out from CNN International to enquire if you are available today to join us on Connect the World at llaET to discuss the coronav irus. Migh t this be a possibility? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households worldwide including in the USvia DIRECTV. • CNN International is the number one internat ional TV news channel according to all major media surveys across Europe, the Middle East and Africa, the Asia Pacific region and Latin America. • In September 2019 CNN .com had 162 million unique readers globally per month and 114 million mobile reade rs a month, leading the BBC,Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) {cell) joanna.hynds@turner .com ■ go there NIH-002062 Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy, but the personal views of the originator. If you have received this email in error, please notify the sender by return e-mail and delete it from your system. You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Turner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks Internationa l Limited (Company No. 2803512), Turner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News Interna t ional Limited (Company No. 5001368) are incorpo rated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002063 From: Date: (b)(6) Sun, 9 Feb 2020 07:08: 49 -0500 Conrad, Patricia (NIH/NIAID) [E) Fwd: CNNI Interview Request: Or. Anthony Fauci, To: Subject: Sent from my iPhone Begin forwarded message: From: "Hynds, Joanna (NE)" Dat e: February 9, 2020 at 6:06:15 AM EST ------~~ To: "Fauci , Anthony (NIH/NIAID) [E]" CbH > Cc: "Tejera, Isabel (Intern)" , "Lovejoy , Hannah (NE)" Subject: CNN I Interview Request: Dr. A nthony Fauci, Dear Dr Fauci, I hope you are well ! I am reaching out from CNN International to enqui re if you are available today to join us on Conne ct th e World at ll a ET to discuss the coronavirus. Might this be a possibilit y? It would be great to arrange this. Background on CNN • CNN International reaches more than 250 million households wor ldwide including in the US via DIRECTV. • CNN International is the number one international TV news channel according to all major media surveys across Europe, the Middle East and Afr ica, the Asia Pacific region and Latin America . • In September 2019 CNN.com had 162 million uniqu e readers globally per mont h and 114 mil lion mobi le readers a mont h, leading the BBC, Yahoo and New York Times. Best, Joanna Hynds Planning Desk CNN International + 44 207 693 1640 (office) + (b)(6) ( cell) NIH-002064 joanna.hynds@turner.com mm go there Information in this email including any attachments may be privileged or confidential and is intended exclusively for the addressee. The views expressed may not be official policy , but the personal views of the originator. If you have received this email in en-or, please notify the sender by return e-mail and delete it from your system . You should not reproduce, distribute, store, retransmit, use or disclose its contents to anyone. Please note we reserve the right to monitor all e-mail communication through our internal and external networks. Turner and the Turner marks are trade marks of Tmner Broadcasting System Inc and are used under licence. Turner Broadcasting System Europe Limited (Company No. 1927955), Turner Entertainment Networks International Limited (Company No. 2803512) , Tmner Broadcasting System Holdings (Europe) Limited (Company Number 2802926) and Cable News International Limited (Company No. 5001368) are incorporated in England and Wales and share the same registered office at Turner House, 16 Great Marlborough Street, London WlF 7HS. NIH-002065 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:33:50 +0000 Janet Tobias RE:Backgroundquestion Janee: Nothing definite on this . To my knowledge , no one has specifically looked at real cross-reactivity although there have been specu lation that because there is about 80-90% homology between nCo V and SARS that there may be some use of the mAbs made against SARS for nCo V. I have not seen any data where people took sera from patients with nCoV and checked if it neutralized SARS and vice versa. Best, Tony -----Original Message----From: Janet Tobias Date: Sanrrday,February 8, 2020 6:27 PM To: Fauci, Anthony (NIH/NIAID) [E] ______ Subject: Backgroundquestion --------=,-,--:= _> Cb _<_· Dear Tony: I have a background question as I am wading through reading as much as possible on the 2019 coronavirus. Do we know if the antibodies 1hatcan neutralize SARS are also effective against the 2019 coronavirus? ] may be complete ly off track, but just liying to think through some things l am reading. Janet Sent from my iPhone NIH-002066 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 9 Feb 2020 03:28:39 +0000 Lenardo, Michael (NIH/NIAID) [E] RE: Hope you're doing well. Thanks, Mike. Am hanging in there. From: Lenardo, Michael (NIH/NIAID) [E] Se nt: Saturday, February 8, 2020 5:18 PM --------- To: Fauci, Anthony (NIH/NIAID) [ E] -------=- (b) ~ > (b)c-c (= > Subject: Hope you're doing well. Hi Tony, Was just leaving the lab and saw your car out in front of build ing 31. Hope you're doing well! I'm sure you're busy with the coronav irus crisis. You continue to be my inspiration! Best wishes, Mike Michael Lenardo M.D. NIH Distinguished Investigator Chief, Molecular Development of the Immune System Section Laboratory of Immune System Biology, Director, Clinical Genomics Program, Nationa l Institute of Allergy and Infectious Diseases Nationa l Institutes of Health Building 10, Room 11D14 10 Center Drive, MSC 1892 Bethesda, MD 20892-1892 USA Tel: (b)(6) (O); FAX: 301-402-8530 (b)(6) Email: (b)(6)(M) ------ ASSISTANT:Gloria Rodela Tel: (b)(6) (b)(6) Email NIH-002067 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 20 :54:52 +0000 (b)(6) To: Subject: Attachments : FW: Invite nejmoa2001316.pdf Here it is. As discussed, let us re-rea d and convene sometime tomorrow to outline our approach. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX : (301 496-4409 E-mail : Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Saturday, February 8, 2020 12:51 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Invite ------~~ Cb)( > Tony, As I am sure you are aware we recently web released the attached paper providing some initial estimates of key transmiss ion paramete rs associated with nCoV-2019 virus . It will soon be coming out in a print issue and we would like an editorial to go with it. Might you be w illing/interested in authoring such a piece? Our editorials are typically about 800 words wit h up to 10 references . As soon as you provide it to us we will web release it and the n link it with the attached article in an upcoming print issue. Are you interested? Please confirm no potential COis. Thank you for considering, Lindsey Lindsey R. Baden, MD Deputy Editor New England Journal of Medicine NIH-002068 This email message is a private communication. The information transmitted, including attachments , is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002069 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :44:45 +0000 Robinson, Sae;Conrad, Patricia (NIH/NIAID) [El naugenstein@wtop.com RE: request for info from WTOP's Neal Augenstein To: Cc: Subject: Sae: I assume that this is taken care of with the interview that I just gave fo r WTOP today Thanks, Tony From: Robinson, Sae Se nt : Saturday, February 8, 2020 7:57 AM To: Conrad, Patricia (NIH/NIA ID) [El-------~= (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Re: request for info from WTOP's Neal Augenstein We will call at 11:20 am. Thank you both! On Feb 8, 2020, at 07:52, Conrad, Patricia (NIH/NIAID) [El wrote: --------- (b)(6)> Dr Fauci can be available for an interview between 11 am ET and 1130 am ET. Please call him at (b)(6) back up cell at (b)(6) What is the exact hit time? Sent from my iPhone On Feb 8, 2020, at 7:42 AM, Fauci, Anthony (NIH/NIAID) [E] (b)( > wrote: -------Sae: Patty wi ll get back to you today. Best, Tony From: Robinson, Sae Date: Saturday, February 8, 2020 7:06 AM To: Conrad, Patricia (NIH/NIA ID) [EI-------~~ ________ NIH-002070 Cb _>_C_,; Fauci, (b)(6) Anthony (NIH/NIAID) [E] Subject: Re: request for info from WTOP's Neal Augenstein -------- Good morning. I'd like to follow up on yesterday's inquiry from our repo rter Neal. If Dr. Fauci is available to address the concerns of this cruise ship in Japan with Corona virus (re: air circulation system) today, we'd love him to have him on. Unfortunately, the first available interview time is after 11 a.m. If it works, please let me know. This time, we'd like to record an interview to be used for air so we have some flexibility. Thank you ! Sae Robinson WTOP News 202-895-5060 On Feb 7, 2020, at 12:59, Augenstein, Neal wrote Begin forwarded message: From: "Conrad, Patricia (NIH/NIAID) [E]" (b)( > Date: February 7, 2020 at 12:17:40 PM EST To: "Augenstein, Neal" Subject: RE: request for info from WTOP's Neal Augenstein Dr Fauci asked that I respond - he is in back to back meeting today up until about 7 pm. If you want to speak with him tomorrow-we might be able to make that work Patricia L. Conrad Public Health Analyst and Special Assistant to the Director NIH-00207 1 National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liabi lity for any statement made that are sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Augenstein, Neal Date: Friday, February 7, 2020 8:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b) (6)> Subject: request for info from WTOP's Neal Augenstein Hi, Dr. Fauci. Hope you're well Spokewith some passengersaboardthe Diamond Princesscruise ship in Japan, where the numberof coronaviruscasesonboardare jumping. Can we do a brief interview re: thoughts on quarantiningon board ship (with, I would assumea closed circulatingair system) versusevacuatingthem? I'm available at your earliest convenience.Or, if you'd like to just email some thoughts, that'd be great. Thanksand best. NIH-002072 Neal Augenstein Reporter 103.SFMand wtop.com Washington, DC (b)(6) cell 202-895-5060 newsroom naugenstein@wtop.com Twitter: @AugensteinWTOP Skype: WTOPNealAugenstein NIH-002073 From: Date: To: Cc: Subject: desktop? Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17:30:45 +0000 Awwad, David (NIH/NIAID) [C];Folkers, Greg (NIH/NIAID) [El NIAID ODAM RE: David ·• how do we put a link to the Coronavirus public folder on ASF' Monday is fine . --------- From: Awwad, David (NIH/NIAID) [C) Date: Saturday , February 8, 2020 12:11 PM To: Folkers, Greg (NIH/NIAID) [E]--------=- (b)( > (b""" )(=6)> Cc: NIAID OD AM Subject: Re: David -- how do we put a link to the Coronavirus public folder on ASF' desktop? I will add Monday, unless you want me to connect now. Sent from my iPhone On Feb 8, 2020, at 11:42 AM, Folkers, Greg (NIH/NIAID ) [El wrote: (b)(6) Disclaimer: Any third-part y material iu this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. Lt does not necessa rily repr esent my views nor those of NIA ID, N IH, HHS, or the U.S. gove rumeut. NIH-002074 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 17 :29 :51 +0000 To: Conrad, Patricia (NIH/NIAID) [E) Subject: FW: Fox and Friends video -- US confirms first Ame rican coronavirus death/ AS Fauci http;/ /bit.ly /2tltgne Fyi. It came out well. From: Folkers, Greg {NIH/N IA ID) [E) (b)(6) Se nt: Saturday, February 8, 2020 11:34 AM Subject: Fox and Friends video -- US confirms first American coronav irus death/ AS Fauci http://bit .ly/2tltgne Disclaimer : Any third-party materia l in this email bas been sbared for internal use under fair use provisions of U.S. copyrig ht law, without further verification of its accuracy /veracity . It docs not necessarily repre sent my view s nor those of NlAlD, NIH , HHS, or the U.S. government. NIH-002075 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 8 Feb 2020 17 :24 :25 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) RE: CNN Interview Request : Dr. Anthony Fauci I believe that we can do t his if they do it ear ly in the 10:00 AM segment on Monday . We may also be able to encroach a bit on Diane Reh m's podcast (10:30) since I believe that t his is taped. I leave this up to you and so please get back to them and work it out if you can. Jim Sciutto CbH6)), Thanks. From: Griffin, Janelle Date: Saturday, February 8, 2020 11:33 AM To: Fauci, Anthony (NIH/NIAID) [E)-------~= Subject: CNN Interview Request: Dr. Anthony Fauci Importance: High (b)(6) Good mornin g Dr. Fauci , I hop e this email finds you doing well. I'm reaching ou t on behal f of Newsroom w/ Popp y Harlow & Jim Sciutto hop ing you can join for an interview. Are you available to join CNN this Monday February l 0th in the 1Oa et hour? This would be live for about 5-7 minutes to discuss developments regarding the coronavirus. Please feel free to contact me via email or at ------ Cb)(6) to let me know. Thanks for your time- I look forward to hearing from you soon. Janelle Griffin-Butts Editorial Producer, CNN Email: jane lle.gr iffin@tu rn er.com I Twltter: @janellegCN N NIH-002076 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 8 Feb 2020 03:23:51 +0000 Conrad, Patricia (NIH/NIAID) [E) RE: Details for "Fox & Friends" Tomorrow (Saturday) LIVEat 8:30am ET Date: To: Subject: I am OK with their coming to the house w ithout a truck. I will call you in the AM. From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 7:42 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=- (b)(6)> (b) '""' (= 6)> Subject: Fwd: Details for "Fox & Friends " Tomorrow (Saturday) LIVE at 8 :30am ET Am at din ner. Will call u later Sent from my iPhone Begin forwarded message: From: "Zuccaro, Alexandra" Date: February 7, 2020 at 7:16:21 PM EST To: "Conrad, Patricia (NIH/NIAID) [E]" (b)(6)> Subject: RE: Detail s for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET -------~= They'll be at his house. Sorry, the truck wasn't available, but th is will work just as well too! ----------- (b)(6) From: Conrad, Patricia (NIH/NIAID) [E) Date: Friday, February 7, 2020 6:51 PM To: Zuccaro, Alexandra Subject: (EXTERNAL]Re: Details for "Fox & Friends" Tomorrow (Saturday) LIVE at 8:30am ET Will they set up outside his house or is this the trick that he goes into it for the interview? Sent from my iPhone On Feb 7, 2020, at 6:49 PM, Zuccaro, Alexandra wrote: Hi Everyone, NIH-002078 Babu Aryankalayil is set to arrive at (b)(6) around 7:30am/est tomorrow for our interview with Dr . Anthony Fauci. Babu, please give Dr. Fauci a call on his cell about 15 minutes before arrival. The IFB and Pl Numbers are below. Please let us know if you have any questions, and please also let us know what REM this will be on. "Fox & Friends" DATE: Saturday, February 8th CREW ARRIVAL TIME : 7:30am ET ------------- ADDRESS: (b)(6) LIVE TALK BACK:8 :35am ET - 8:40am ET with Pete Hegseth, Emily Compagno, & Jason Chaffetz Satellite Window : 0700 -0800 GUEST: Dr. Anthony Fauci TOPIC: CORONAVIRUSCRUISESHIP LATEST GUESTCONTACT: Dr. Anthony Fauci, Conrad cell : (b)(6)cell:-_:..!:====:::!..: CREW CONTACT: Babu Aryankalayi l, (b)(6) (b)(6) / Media contact Patricia (b ~ )- (~ 6) ----- (b)(6)/ F&F NYC CONTACTS: ----- Technical Director: Todd Boone: Phone (b)(6) email: todd.boone@foxnews.com F&F Control Room Contact: Tami Radabaugh, (b)(6) email: Tami .Radabaugh@FOXNEWS.COM Pl: 800-369-5815, Camera and Tech: (b)(4) Producers: (b)(4) IFS: 800-369-6719 ACQ and REM Coordinator : 212-301-3200 NY Transmission : 212-301-3100 NY Sat Desk {Bookings) 212-301-3400 A.M . Emergency Contac t: Mary Carol Butterfield: Cell: (b)(6) & NYC Greenroom (212) 301-1983 email: Mary.Butterf ield@FOXNEWS.COM Thanks, Alexandra Zuccaro NIH-002079 "Fox& Friends" Fox News Channel 1211 Avenue of the Americas, 2nd Floor New York, NY 10036 Cell : (b)(6) Alexandra .Zuccaro@FOXNEWS .COM This message and its attachments may contain legally privileged or confidential information. It is intended solely for the named addressee . If you are not the addressee indicated in this message (or responsible for delivery of the message to the addressee) , you may not copy or delive r this message or its attac hments to anyone . Rather, you should permanently delete this message and its attachments and kindly notify the sender by reply e-ma il. Any content of this message and its attachments that does not relate to the official business of Fox News or Fox Business must not be taken to have been sent or endorsed by either of them. No representation is made that this ema il or its attachments are without defect. NIH-002080 From: Date: To: Cc: Subject: Attachments : Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 20:20:58 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl Re: Important Brief Conversation image0Ol.gif I know. Glad we could work it out On Feb 7, 2020, at 11:48 AM, Mellors, John W ------ (b)(6) wrote: Dear Tony, Approva l receive d from DHHS. The shipm ent of remdesivir to China is on it's way. No need to connect. Thanks, John From: Fauci, Anthony (NIH/N IAID) [E) Date: Thursday, February 6, 2020 7:04:53 PM To: Me llors, John W (b) ( > Cc: Conrad, Patricia (NIH/N IAID) [E] {NIH/NIAID) [C] (b)(6) Subject: RE: Important Brief Conversation (b)(6)> -~------------~~ (b)( ; Barasch, Kimberly John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Me llors, John W (b)(6) Date: Thursday, February 6, 2020 5:38 PM To: Fauci, Anthony (NIH/N IAID) [El ·_...:._ Cc: Mellors, John W (b)(6)> Subject: Importan t Brief Conversation ---------------=~ __:....:.,..:.~-------------- (b)(6) Dear To ny , Cliff Could we speak brief ly about an important interna tio nal coronavirus trial that is in je opardy? My mob ile phone number is ----- (b)(6) John NIH-00208 1 John W . Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professo r and Endowed Chair for Elimination of HIV and AIDS University of Pittsburgh Schoo l of Medic ine Scaife Hall , Suite 818 3550 Terrace Street Pittsburgh, PA 15261 Tel : (b)(6) Fax: 412 383-7982 E-mail: (b)(6) Visit our Division website: http://www. dept-med .pitt.edu/l D/ Read the "ID Pitt Stop" blog: https://idpittstop.word press.com Like us NIH-002082 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 15:37:53 +0000 Date: (b)(6) To: Subject: RE: NIH posit ion on travel to Singapore??? Go t o CDC we bsite. There are no t rave l alert s fo r Singapore and so f or now it is OK t o trave l t here. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------------= ~ (b)(6) From: Se nt : Friday, February 7, 2020 9:03 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Fwd: NIH position o n travel to Singapore??? -------- jim lynch is asking for sources of info for travel advice re: coronavirus . ___ Singapore . any suggestions? Cb _> _<_6) is planning to go to ---------- Forwarded message --------From: James L (b)(6)> Date: Thu, Feb 6, 2020 at 8:16 AM Subject: NIH position on travel to Singapore??? To: 00~ Hi (b)(6) ------- (b)(6) is scheduled to t ravel to Singapore on March 9th for a week . What is the best source of up-to -date information and travel recommendations related to the coronavirus? Thanks NIH-002083 Jim (b)(6) NIH-002084 From: Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 10:46:54 +0000 NIAIDODAM FW: Royal Society of Medicine london Date: To: Subject: Let us discus. -----Original Message ----From: Ian Hosein _________ (b ",a"S"'" )(= Date: Friday, February 7, 2020 5:20 AM To: Fauci, Anthony (NIH/NIAID) [E]._______ Subject: Royal Society of Medicine londo n ------~~= _> Cb _<.... Hello Dr Fauci, By way of introduction , 1was Jim Mac Lowry 's last fellow at the NIH and have been work ing in the UK since then as a medi cal microbio logist and hospital epidemio logis t. J am the lead medical microbiologist at the Royal Society of Medicine in the UK and was wondering about your availabili ty please to speak at a conference on emergent Coronavirus threats to be held at the RSM on November 24th coming? The RSM is a unigue educa tional cha1ity here and we have councils covering all aspects of healthcare. The program is still developing but I wanted to check on your avai lability quick ly- we have an academ ic fond to which I can apply to cover your trip but will need to do so soon. Jt was both exciting and inspirational being a senior staff fellow at the Nll-1- my background is international; (b) (6) and the internationa l perspective s at the NIH were so encouraging. All non- American fellows recognised the nationa l strateg ic remit of the NIH for the US , but I have often wondered if an assessment has ever been made of how fellows like myself have brought the spirit of that institution to other nations. With kind regards , lan --,------------,---,-,,-----,-....,...,.,...-----,,--,-,--- lan K Hosein MD FCAP FRCPath MBA Royal Society of Medicine London Mobi le--- (b ~)~(= 6) Sent from my iPad NIH-002085 From: Date: To: Subject: Attachment s: Please set up a call. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:56:15 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Comment on NEJM details of "asymptomat ic" contact in Germany nejmc2001468_appendix.pdf Happy to do over the weekend or Friday evening. From: Ian Ingram Date: Thursday, February 6, 2020 1:34 PM To: Fauci, Anthony (NIH/NIAID) [El ------~~ (b)( > Subject: Comment on NEJM details of "asymptomatic " contact in Germany Hi Or. Fauci, I'm fi lling in for Molly Walker on the coronavirus beat while she's covering a meeting for MedPage Today, but I wanted to see if you could were available to offer your quick reaction to the Supplement ary Index publ ished today (attached) in the New England Journal of Medicine regarding the widely reported asymptomati c contact in Germa ny. Looking at the patient's daily take on how she felt it's unclear to me whether this qualifies as symptomatic or not . I imagine this will be disputed. Best regards, - Ian Ian Ingram Dep uty Managing Edi tor MedP age Today LLC (b)(6) iin gram @m edpaget oday.com medpagetoday. com NIH-002086 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:53: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: BuzzFeed News; 2019-nCoV vaccine development questions To: Cc: Subject: Please set up a call with this person. Happy to do over the weekend. From: Dan Vergano Date: Wed nesday, February 5, 2020 3:18 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Stover, Kathy (NIH/NIA ID) [E] (b)(6) Subject: BuzzFeed News: 2019-nCoV vaccine development questions Dr. Fauci, As you may recall, I'm a science reporter at BuzzFeed News. We wonder if you might have any perspective (or might recommend someone to commen t) for a novel coronavirus story we are w riting for this weekend, regarding vaccine efforts . In short, we wonder how you see an eventual vaccine playing a role in the future of the outbreak? CDC has described the virus as not mutating as much as influenza -- does that suggest a vaccine would provide more than seasonal protection? In the long te rm, we had a few other questions. Is thi s something you could see added to the MM R protoco l for the general public, or only in regions where there are local outbreaks (is there an analogy to SARSor MERSvaccines in this contemplated use)? Is the re any aspect of a race against time in vaccine development if this coronavirus is seasonal like influenz a? We are basically trying to understand where a vaccine fits into the future response to this new virus. we asked you these sort of quest ions about the Zika vaccine efforts and your perspective really helped a lot. Apologies for all the quest ions, if you had any perspective, we'd be grateful Dan Vergano BuzzFeed News (b)(6) cc: Kathy Stover ----- (b)(6) Dan Verg ano I Science Desk (DC) I BuzzFeed News 1630 Connecticut Ave. 7th Floor, Washington DC 20009 Send secure tips -- cont act .buzzfeed.co m NIH-002089 From: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:45:34 +0000 Folkers, Greg (NIH/NIAID) [E] RE: ASF / please see tab le from 1-29-2019 NEJM paper on Wuhan cases Date: To: Subject: Very interesting! ! From: Folkers, Greg (NIH/NIAID) [E] (b)(6)> Date: Thursday, February 6, 2020 2:22 PM To: Fauci, Anthony (NIH/NIAID) [E]--------=-c-c= Cc: Ooepel, Laurie (NIH/NIAID) [El (b)( •>; Eisinger, Robert (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [E] (b)( >; Lerner, Andrea ":'---:----:-~===:::.;..--~~ (NIH/NIAID) (E] (b)(6)]; Marston , Hilar y (NIH/ NIAID) (El (b)(6) Subject: ASF / please see table from 1-29-20 19 NEJM paper on Wuhan cases Please see next to last line, wh ich gives% of transmissions with "no exposure to either market or person w ith respiratory symptoms" (b) (5) N Engl J Med . 2020 Jan 29. doi: 10.1056/N EJMoa2001316. [Epub ahead of print] Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-lnfected Pneumonia. x1, Zhou L1, Tong v1, Ren R1, Leung KSM1, Lau EHY1, Wong JY1, Xing x1, Xiang N 1, Wu Y1, Li C1, Chen Q1 , Li D1, Liu r 1, Zhao J1, Li M 1, Tu W 1 , Chen c1, Jin L1, Yang R1, Wang Q1 , Zhou s1, Wang R1, Liu H1, Luo Y1, Liu Y1, Shao G1, Li H1, Tao z1, Yang Y1, Deng z1, Liu 8 1, Ma z1, Zhang Y1, Li Q1, Guan x1, Wu P1, Wang Shi G1, Lam TTY1, Wu JTK1, Gao GF1, Cowl ing BJ1, Yang B1, Leung GM 1, Feng z1. DOl: 10.1056/NEJMoa2001316 NIH-002090 lklore January l 60(21 S6 (26--32) e(r 11:&e)-y _ 9) JanLE&l'Yl2 -:I u (N • llO) 22 6 ( S.-89) - no./cowno. (") els yr '1S-64 r - no./tot no. (%) posure 15 OI)'- no./tot I no. (") We1ma et posur Hu II n SeafoodWholewle M ,kc Other (26) 24/47 (5 ) 65 ~' e, 0/243 0/47 12/◄ 7 yr 1S muk b-ulnot Hu1n•n S 1food H C n:c-1 Con c~rl' wor c-r- no /tot1I no , ('(,) Rc,duc~ denom1na ors 1ndic le m1ssin da t OJlJO 39[24 (16) H/130(25) 06/24 (0) 49/lJO(lSJ 11/47 (23) 03/:J.48(42) &/ 30 (37) 31/47 (66) 147/24 (59) 62/ 30 (48) J0/O (641 12/196116) s 26/ 47 (5S) 19/196 (10) 5/81 (6) U/196 (7) 0/81 "''' (9) Hi/47(30 12f47 (26) He,I January l 1 an11 r,r 11 [ - u•1 (N • 471 30/196 (15) 21/83 (25) 141(196 {72) 59/81 (73) a,m (1) 0/1.7 P ccMu es m1r no to (6) 100 b« use o round n Disclaimer: Any third-party materia l in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNIAID , NIH , HHS , or the U.S. government. NIH-002091 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:38:45 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Latest Please set up a call with David for the weekend. From: davidwillman (b)(6) Date: Thursday, February 6, 2020 2:02 PM To: Fauci, Anthony (NIH/NIAID) [E)------~~ _______ Subject: Latest Cb _H_6) Hi Tony, I know you must be swamped by matters related to the coronavirus. Nonethe less, I'd really like to confer, even if briefly. Would you have any window by phone today, over the weekend or next week? I'll also call Kim Barasch, per your recent guidance. I'm researching an article that will chiefly explore the status of the Defense Department's advanced development and manufacturing facility in Alachua, Florida. On a related note, I'm also curious re the three HHS/BARDAfacilities. Best, David David Willman Washington Post 202-334-7081-desk Cb)(6) -mobile 301-656-3401 --alternate desk david.w illman@washpost .co m ------ (b)(6) NIH-002092 From: Date: To: Subject: Let us discuss. Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:11: 47 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Reporter working on coronavirus vaccine story Maybe over the weekend From: Morris , Amanda Se nt: Thursday, February 6, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E] ------=-c (b)'""' (6) = Subject: Reporter working on coronavirus vaccine story Hi Anthony, I hope this emai l finds you well! My name is Amanda Morris and I'm a bioscience reporter at the Arizona Republic, part of the USAToday network. I'm reaching out because I'm currently working on a story about how some ASU researchers (Brenda Hogue, Bert Jacobs and Shawn Chen) are trying to develop strategies to make a vaccine against the new coronav irus as well as a general platform they can use in the case of future new coronavirus strain out breaks in humans. I know globally there are many researchers trying to develop a vaccine for this new coronavirus, and that the NIH is working with Moderna to do so -and hopes to start testing with in a few months. I'm wondering if I can talk to you over the phone and ask a few questions about the work that NIH is doing, and what the broader challenges are for developing a vaccine? I'd like to have broader context about vaccines for our readers. Please let me know as soon as possible. You can call or text me at All my best, Amanda Mo r ris Bioscience Reporter for The Arizona Republic Work phone: 602-444-8739 After hours and weekends, you can call or text my cell: ___ Email : amor ris@gannett .com NIH-002095 (b _ )_(6J _. ----- (b)(6) Thank you! From: Date: Fauci,Anthony (NIH/NIAIO)[E) Fri, 7 Feb 2020 03:04:53 +0000 Mellors, John W Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID)[CJ RE: Important Brief Conversation To: Cc: Subject: John: Please give me office a call tomorrow and they will set up a time to connect us. Best, Tony From: Mellors, John W (b) (6) Date: Thursday, February 6, 2020 5:38 PM -------------~~ To: Fauci,Anthony (_ N_ IH.:.. /_ N_IA_ID ..:. )...:. [__.; E)~ ~------------ (b) _(_ 6) Cc: Mellors, John W (b)(6) Subject: Important Brief Conversation Dear Tony, Cliff Could we speak briefly about an importan t international coronavirus trial that is in jeopar dy? My mobile phone number is ----- (b)(6) John John W. Mellors, M.D. Chief, Division of Infectious Diseases Distinguished Professor and Endowed Chair for Elimination of HIV and AIDS Univer sity of Pittsburgh School of Medicine Scaife Hall, Suite 818 3550 Terrace Street Pittsburgh , PA 15261 Tel: CbH6) Fax : 412 383-7982 E-mail Cb) (6)l Visit our Division website: http ://www .dept-me d.pitt.edu/ lD/ Read the "ID Pitt Stop" blog: https://idpittstop .wor dpress .com Like us (I NIH-002096 From: Date: To: Subject: Fauci, Anthony (NIH/NIAI0) [E) Fri, 7 Feb 2020 03:01:07 +0000 Howard Bauchner RE: Subtitled Coronavirus Video Howard: Thanks for the feedback. Best, Tony From: Howard Bauchner Date: Thursday, February 6, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Subject: FW: Subtitled Coronavirus Video ------ --.~ Tony First live stream/podcast now with Chinese interpretation. URL below . Second live stream/podcast will be put up tomorrow. URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the question, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Editor in Chief of JAMA and the JAMA Netwo rk Please respect the confidentiality of t his email listen to my chats with author s From: Karen Adams- Taylor Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner < Howard .Bauchner@ jamanetwork.org >, Annette Flanagin , Michae l Berkwits < Michael.Berkwits@jamanetwo rk.org >, Tom Easley , Brian Shields < Brian.Sh ields@ama -assn.o rg>, Betsy Solaro , Sean O'Donnell NIH-002097 , Tiffany Jones Subject: Subtitled Coronav irus Video The 1/27 Fauci subtit led video is now live: https ://jamanetwork .com/journals/jama/pages/coronavirus alert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Kare n Ad ams-Taylor Vice President, Publishing Production Operations JAMA Network ™ 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002098 - From: Date: Fauci, Anthony (NIH/NIAIO) [E) Fri, 7 Feb 2020 03:00:35 +0000 To: Greg Folkers Jennifer (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El Subject: FW: Subtitled Coronavirus Video (b)(6) ;Billet , Courtney (NIH/NIAID) [E]; Routh, fyi From: Howard Bauchner Se nt: Thursday, February 6, 2020 6:39 PM ------~= To: Fauci, Anthony (NIH/ NIAID) [El Subject: FW: Subti tled Coronavirus Video (b)( > Tony First live stream/podcast now with Chinese interpretation . URLbelow. Second live stream/podcast will be put up tomorrow . URLbelow . Couple big thank yous from prominent science writers - NYT/WSJ - said learned more listening to you for 30 minutes then everything they read in the last few weeks. My response whe n you have a very wise scientist, who hears the question and answers the quest ion, and has 40+ years of experience we should listen and learn. Be well. HCB Howard Bauchner, MD Edito r in Chief of JAMA and the JAMA Network Please respect the confidentiality of t his email Listen to my chats with authors From: Karen Adams-Tay lo r Date: Thursday, February 6, 2020 at 4:59 PM To: Howard Bauchner , Annette Flanag in , Michae l Berkwits < Michael.Berkw its@jamanetwork.org >, Tom Easley , Brian Shields , Betsy Solaro , Sean O'Donnell , Tiffany Jones Subje ct: Subtitled Coronav irus Video NIH-002099 The 1/27 Fauci subtit led video is now liv e: https :// jamanetwor k.com/journa ls/jama/pages/coronav irusalert The 2/6 Fauci update video will go to the trans lator tomorrow. -Karen Karen Adam s-Taylor Vice President, Publishing Production Operations JAMA Network rM 330 N Wabash Ave, Ste 39300, Chicago, IL 60611 ----- (b)(6) T jamanetwork.com NIH-002100 From: Date: (b)(6) Thu, 6 Feb 202015:09:43 -0500 To: Folkers, Greg (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: Re: ASF--- Morens + Daszak +Taubeneberger paper I agree. I will not be a co-author On Feb 6, 2020, at l :59 PM, Folkers, Greg (NIH/NIAID) [E] CbH wrote: ----------- (b) (4) So the question to you - do you want to be part of this? ie be a coauthor I would vote no - it wud look weird to add you as a coauthor now. Plus, plate too full. ..... Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisionsof U.S. copyright law, without further verification of its accuracy/veracity. It does not necessarily represent my views nor those ofNWD , NIH, HHS, or the U.S. governme nt. NIH-002 104 From: Date: Fauci, Anthony {NIH/NIAID) [E] Thu, 6 Feb 2020 17:36:11 +0000 (b)(6) To: Cc: Subject: (b)(6) RE: nCoV: Heads-up Thanks, Jim. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mai l (b)( The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Nationa l Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -------------------------~ From: Date: Thursday, February 6, 2020 10:33 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b) (6) (b)(6) -------- (b)(6) Subject: nCoV: Heads-up . We will keep you updated. Best. John and Jim French dru gmaker Sanofi workin g on coronavirus initiative CHINA-HEALTH/SANOFI (PIX):French initiative drugmaker Sanofi working on coronavirus PARIS, Feb 6 (Reuters) - French drugmaker Sanofi will announce a new coronavirus initiative within the next two weeks, its chief executive said on Thursday , adding that it wants to present something concrete and not add to "fantasies". At least a dozen drngmake rs are working on vaccines or antivira ls to help those infected with the fast-spreading virus that has killed more than 500 people in China, but several have warned that development of treatments will take time. NIH-002105 "We have seen a flurry of activities from other companies," CEO Paul Hudson told a news conference after Sanofi published 2019 results on Thursday. "We are one of the few companies that has the expe1iise to know when it is just a fantasy, or when it could be real. In the next week or two, you will see something more confinnatory about the approach we will take." Hudson declined to give further details. Sanofi had already said it was sharing its expertise and data acquired from other outbreaks with the Coalition for Epidemic Preparedness Innovations (CEPI), which is working with biotech businesses to try to develop a vaccine candidate for the coronavirus. Britain's GlaxoSmithKline is also collaborating with CEPI. "The objective here is not a newspaper headline, it is real work that will make a difference ," Hudson said. (Reporting by Matthias Blamont Writing by Sarah White Editing by David Goodman) NIH-002106 From: Date: To: Cc: Subject: Attachments: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 16:28:04 +0000 h iattf@washpost.com Redfield, Robert R. (CDC/0D);Fauci, Anthony (NIH/N IAID) [E] Proposed OpEd Redfield and Fauci - Coronavirus OpEd - 02-06-2020 - FINAL.docx Fred: I hope that all is well with you . (b)(6) Within this context, Bob Redfield -------------------and I have written an OpEd on the government response to the novel coronavirus (bH6J. outbreak. Would the Post have any interest in this? Many thanks. Best regards , Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NIAID by one of its representatives . NIH-002107 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:34:57 +0000 From: Date: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] To: RE: Requested coronavirus talking points for press conference Talking Points for NIAID Director Dr. Fauci - press conference - 02-06-2020 Fauci Press remarks with tracked edits.docx Subject: Attachments : Oooops! Forgot the attachment. Here it is. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Thursday, February 6, 2020 9:34 AM To: Billet , Courtney (NIH/NIAID) [E) (b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) >; Folkers, Greg (NIH/NIAID) [E] (b)(6)>; Marston, Hilary (NIH/NIAID) [E] (b)(6); Routh, Jennifer ":": (N "".".' l'."':" H/-::N"."."' IA '."".' l':": D):-:[~E]:-====-.:--_.;.. (bc-c )(= ; Stover, Kathy (NIH/NIAI D) [E] (b)( > Subject: RE: Requested coronav irus talking points for press conference ------~= Here is my revised and updated press remarks with my tracked edits showing. Please accept edits, do a spell and grammar check and resubmit. Also, put a copy in my fol der . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b)(6) NIH-002 114 FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6) Date: Thursday, February 6, 2020 9:16 AM To: Fauci, Anthony (NIH/NIAID) [E]------= (b) '""(= 6)> Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Folkers, Greg (NIH/NIAID) [E] (b)(6); Marston, Hilary (NIH/NIAID) [El (b)( >; Routh, Jennifer ":": (N "".":' 1:-:H/7N"."."' IA '.'"':' l-::D):-:[~El:-===~--~ (b"""' )(,=,; 6); Stover, Kathy (NIH/NIAI D) [El (b)(6) 1 Subject: FW: Requested coronavirus talking points for press conference HHS has asked us for your talking points fo r the press conference by 11am. We were planning to resubmit these. As was the case last time, this is a placeholder for the WH to know the outlines of what you would say. This is not a script. Is it OK for us to send th is to Bill? (b)( > From: Selgrade, Sara (NIH/NIAID) [El Date: Thursday, February 6, 2020 8:37 AM To: Fauci, Anthony (NIH/NIAID) [E]______ """' (b""" )(=6) Cc: Conrad, Patricia (NIH/NIAID) [El (b)(6)>; Billet, Courtney (NIH/NIAID) [E] (b)(6); Routh, Jennifer (NIH/NIAID) [El (b)(6); Folkers, Greg (NIH/NIAID) [El (b)(6) Subject: Requested coronavirus talking points for press conference Dr. Fauci, Attachedplease find the requested talking points from your last coronavirus press conference. Plea se let us know if you need anything else . Thanks, Sara NIH-002 115 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 10:58:13 +0000 Collins , Francis (NIH/OD) [El Cassetti , Cristina {NIH/NIAID) [El; Erbelding , Emily {NIH/NIA ID) [E];Conra d, To: Cc: Patricia {NIH/NIAID) [El Subject: RE: Follow up on Addis Meeting Francis: Thanks for the note . Best to have Trevor have his program person who will be leading this effort contact Cristina Cassetti in DMID . Cristina and Emily Erbelding cou ld do all of the necessary and approp riate coordination . Thanks, Tony -------- From: Coll ins, Francis (N IH/OD) [El Date: Thur sday, February 6, 2020 4:56 AM (b)(6) -------=-,--=" (b)(6) -------- To: Fauci, Anthony {NIH/NIAID) [El Subject: FW: Follow up on Addis Meeting See reference to coronav irus research in the note from Trevor. How would you like to coordinate this? FC _____________ From: Trevor Mundel Date: Wed nesday, February 5, 2020 10 :55 PM To: Collins , Francis (NIH/OD) [El Cc: Eiss, Robert (NIH/ FIC) [El ,.;....;;-======- .., (b)(6)> (b)(6) (b,;,; H;;6;J;;-:G:-:-" lass, Roger {N IH/FIC) [El Kedest Tesfagio rgis (b)(6); (b)(6)> Subject: Re: Follow up on Add is Meeting That would be great Francis. You might have seen our announcement th is morni ng on the Coronavirus reponse fundin g and $60M of the 100 is fo r R&D especia lly therapeutics rather than vaccines so we mi ght want a quick call in the next few days to thin k about how we coordinat e this - I've been in touch with Jeremy as we ll. Trevor Trev or Mu ndel , MD, Ph D President , Global Health Program V (b)( F +1.206 .494 .7041 E ------------- (b)((ij (b)(6) Execut ive Assistant Office of the President, Global Health NIH-002 118 (b)(6) (b)(6) (b)(6) Bill & Melinda Gates Foundation www .gatesfounda tion.org From: Collins, Francis (NIH/OD) [El (b)(6)> Date: Wednesday, February 5, 2020 3:11 PM To: Trevor Mundel Cc: Eiss, Robert (NIH/FIC) [El; Glass, Roger (NIH/FIC) [El Subject: RE: Follow up on Addis Meeting Hey Trevor, This is an excellent development. How about I send you a proposal of possible CARITPs for Elioda - in the next 24 hours? Franc is From: Trevor Mundel (b)(6) Date: Wednesday, February 5, 2020 4:43 PM To: Tumwesigye Elioda CbH6l>;Collins, Francis (NIH/OD) [El Cc: (b)(6) Subject: Re: Follow up on Addis Meeting -------- (b) ( > That's great to hear Elioda and congrat ulations, many thanks for letting us know . We will certain ly get back to you shortly to enlist your help w ith the CARI initiative at AU level. Warm regards, Trevor From: Tumwesigye Elioda (b)( > Date: Wednesday, February 5, 2020 1:16 PM To: Trevor M undel; Francis Collins Cc: (b)(6) Subject: Follow up on Addis Meeting Dear Trevor, Greetings from Uganda and indeed Africa . It was pleasure meeting you at the Grand Challenges Meeting in Ethiopia late last year. While there you, Francis Collins and I among others discussed the CARI Initiative and the need to support research, entrepreneurship and innovation in a big way in Africa. We also explored the mechanism for CARI Funding. We were also looking for a mechanism to reach the Committee of Ten (ClO) Heads of State and Government championing Education, Science and Technology in Africa. NIH-002 119 Well allow me to inform you that on 13th Dec 2019, I was elected to chair for 2 years the Ministers of Education and of Science and Technology in all the 55 Members States in Africa. We do this under the Specialized Technical Committee on Education, Science and Technology (STC-ES T). This Saturday on 8th Feb in Addis, as chair of the ST -EST I will attend and speak at the Meeting of the above-mentioned Cl0. The purpose of this message is to let you know of my added responsibilities and related opportunities as well as seek for any update or latest information regarding the CARI init iative . I look forward to intensified communication and collaboration. Regards Dr. Elioda Tumwesigye Minister Science, Technology and Innovation Republic of Uganda Tel: (b)(6) Sent from my iPad NIH-002 120 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 04 :10:50 +0000 Cassetti, Cristina (NIH/N IAID) [El Conrad, Patricia (NIH/NIAID) [El FW : PandemicThreat Reduct ion From: Date: To: Cc: Subject: Simil ar e-Om ail from Dr. Tubb. ------- From: Richard Tubb Date: Thu rsday, January 30, 2020 11:35 AM _To....! : ===~~----- (b)(6)> Cb _>_C6)Fauci, Ant hony (NIH/N IAID) [E] (b)(6) Subject: Fwd: Pandemic Threat Reductio n Good morning Tony. Given your most recent appointment , I wanted to show you the courtesy of letting you know what I have alread y provided to senior leaders at the White House regarding a possible mitigating strategy until the definitive solution to the CoV is available and implemented. The string below includes additional information as to how titanium dioxide can fit into both the White House and the National / International solutions, and the open-source website for the company. Please keep in mind that because this product is already approved and in use in the EU for a variety of commercial uses, the data provided does not specifically address the applications I, and you, are interested in. Ho-\ivever , with a deep understanding of the White House mission, I can say that there is not a big leap in that thought migration. Dr. Jackson has already provided the same material to some of your White House Commission colleagues. I will also be reaching out to another friend of mine from the Bush-now-Trump Administration, Steve Biegun. NIH-002121 I encourage your representatives to meet with the company leadership and scientists while they are in the US next week. Please let me know if you have any questions that I can address. Thank you for once again stepping up to the plate for our Country. v/r Dick ps .. .I remembered this morning where you and I last spoke--Bush (41) funeral. ---------- Forwarded message --------From: Richard Tubb Date: Thu, Jan 30, 2020 at 8:54 AM Subject: Re: Pandemic Threat Reduction ----------- (b) (6) > Good morning Gentlemen, I just spoke with Ronny and believe I need to offer A relevant update and one point of explanation. First, the company's joint venture partner in India is meeting with the Indian government as we speak. It appears likely that in light of the news of India's introduction to the corona virus the government will utilize their "Natio nal Catastrophe Budget" to expedite the funding necessary to secure and execute a contract with this company. Secondly, I w ill attach the open source web site for the company to provide you background information that, out of respect for your time and for the sake of brevity, I left out of yesterday's note. It's important to note a couple of things: This product is already proved and is in use in the EU with all the approvals appropriate for the same. Secondly, in our language, this is a "standoff produ ctr'' -I.e. you apply it once and it continues to decontamina t e and disinfect in the background for up to 1-5 years before retreating. (Depending on the type of use, norma l daily cleaning using their cleaning solution-that is cheaper and more effective than what the application normally would use, e.g. in a hotel-cont inues). The chemical treats anything organic, I.e. bacteria, viruses, voe,bio threats, etc. because it is a catalyst, it is neither used up, nor NIH-002122 does it produce microbial resistance or superbugs. It decontaminates and disinfects surfaces (e,g, airplanes and government cri tical infrastructures) and the air around the surface (and HVACfi lters and air handlers). The leadership will be in DC next week. I highly encou rage any and all potential stakeholders make time to meet with them while they are here . To that end, I had already emailed Dr. Fauci (with whom I worked a great deal on similar chalenges during the Bush Admin istrat ion) before the announcement of his participat ion on the new coronavirus commission, I will also reach out to an old friend and colleague Steve BIEGUN now that he is in the commission . Please feel free to forward the information to others as you deem appropr iate . Thanks, Dick Tubb htt ps://act.g lobal/ Ps...once again, in my haste to get this to you , via iPad, please forgive typos and other apparent crimes against the dictionary . Sent from my iPad On Jan 29, 2020, at 3:15 PM, Richard Tubb --------- (b)(6J> wrote: Gentlemen, Brother s, and Others ... This is Dick Tubb , writing on behalf of Admiral Jack son and Dr. Hofmann (both copied herein). It feels like "old times"- -I'm undecid ed as to wheth er the y are good old times , or otherwise. Regardless , it does feel like we've been down a very simil ar road before . Perh aps we can apply some of th e lessons -learned to th e inevitable problems ahead. NIH-002 123 In light of the current and evolving threat presented by the corona virus, I am writing to you as a courtesy to inform you of a project that Admiral Jackson, Dr. Hofmann, and I have been consulting on. We believe so strongly in the technology, people, and potential that we have been consulting pro bono and currently have no financial stake in the project. While not developed specifically designed for such purposes, I increasingly believe that until a vaccination and treatment for the corona virus is available, this technology may be the last best chance in containing, and eradicating the virus, thereby protecting the homeland, our economy, the Continuity of the Presidency, an Enduring Constitutional Government, our people and our Country. Moreover, reverting to my "lessons-learned, problems-ahead" statement, even after this crisis is over, and a vaccine and treatment procured, it will only be a matter of time until "next time." This letter is proof-positive of that reality. My experiences, especially in the early 2ooo's (e.g. anthrax and other biothreats, SARs, etc.) underpin my beliefs. The technology that provides the solution, both now and in the future, involves a unique formulation of a photo catalytic NIH-002124 nano titanium dioxide solution (the Air Force guys will, of course, understand what that means, so you non-Air Force folks, just buy them a beer and they'll explain it to you) that is safer, more effective, and more cost effective than any other solution. It was developed and approved in the EU, and I have asked the senior leadership of the company to come to Washington DC next week. Dr. Hofmann and I spent the day yesterday with a Chinese "titan" respected by and with access to the most senior government officials, academic and medical giants, and investment and industry captains. I have encouraged , and he has agreed in principal, to follow our recommendations as they relate to their largest airline, and their key facilities. In short, our strategic priority is to first fortify the weak link in the pandemic chain: the airlines. Doing so will provide the time necessary to isolate, contain, and ultimately destroy the threat at its source (Wuhan) ,and in its home (China). As President Bush so commonly stated about a very different threat, we need to fight the battle over there, so that we don't have to fight the battle here. Although President Bush was a true believer in the threat of a pandemic, I believe this threat, and the NIH-002125 threats that are surely to fallow are, in reality , many, many times greater than the threat he envisioned when making that statement. By fighting a possible impending pandemic at its source we will preserve and protect the safety and confidence of our people, and the strength of our economy. Once we have interrupted the threat supply chain, we can then shore up our critical infrastructure using the same technology and process, then assist the Chinese in addressing their challenges, and protect our international allies elsewhere . In that vein, in addition to the Chinese, I have also discussed this technology and strategy with senior proxies for another of my former patients, His Royal Highness, the Crown Prince of Saudi Arabia, and his father, the King. As I noted above , I have asked the leadership of the company to come to Washington (from Germany and Denmark) next week for a variety of meetings. While Admiral Jackson will be "tied up in Texas" for the foreseeable future, please let me know if you would like to meet with myself or Dr. Hofmann, or the company NIH-002126 leadership while they are here, to learn more. Thank you and my best to you all as you plan for and continue to protect our Country, Very Respectfully, Dick Tubb ps. For your SA, I have also attached below the latest sit rep on the coronavirus. Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus Shoreland's Travax News Alert ServiceAbbreviated China: More than 2,800 Cases of 2019-nCoV in 30 Provinces/Municipalities , Mainly in Wuhan ; Cases Exported to 16 Countries WHAT'S NEW According to regional health authorities, more than 1,800 additional , confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291) , Guangdong (207), Zhejiang (173), Henan (168) , and Hunan (143) and in the cities of Chongqing (132), Beijing (19) , and Shanghai (13). Most new cases had a travel history to Wuhan . Almost all the recent deaths occurred in Hubei Province . Twenty more patients have recovered and been NIH-002127 discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional , exported, confirmed cases have been reported (through January 28, 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22) , Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown). All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China . In addition to these exported cases, 7 locally acquired cases have been reported since Monday in Germany (4), Japan , Taiwan and Vietnam. The cases in Japan, Taiwan , and Vietnam reported contact with an obviously ill person from China . In Germany all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan) ; the women states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Updated travel advisories include: 1) Australia: reconsider travel to China ; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province ; 8) Taiwan: avoid all nonessential travel to China. Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Kray, Yevreyskaya Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh , Canada , India, Kazakhstan , Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. All tourist attractions in Tibet Autonomous Region have been closed . Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China ; the situation is critical in many areas and resupply is uncertain. NIH-002128 OVERALL RISK ASSESSMENT The epidemic in China is months from peaking . A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting , the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation, and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately , sequential sequencing of viral isolates over time indicate no significant new viral mutations ; mutations often increase transmission or virulence . WHO assesses the risk of this event to be very high in China , high at the regional level, and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases . The originally implicated animal market, now closed indefinitely, bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear. The degree of human-to-human spread outside of Hubei province remains unclear . A reproductive number, Ro, is estimated at 1.4-2 .5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread. Case fatality is impossible to ascertain at present, and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative. See 20 19 Nove l Coronav irus Outbreak for detailed information . © 2020 Shoreland , Inc. All rights reserved . Travax News Alert items are incorporated into Shoreland's subscriptions . Travax content represents decision-relevant, expert synthesis of real-time data reconciled with new and existing available advice from authoritative national and international bodies . For email service changes , please forward this message to service@shore land .com with your request. If the change should apply to all email subscriptions (Content Changes , Literature Watch and News Alert), please specify that in your request. [Account: SI53213; Recipient: bg .richard.tubb@gmail.co m) NIH-002129 2019 Novel Coronavirus Outbreak Reportcomprehensive Last updated January 28, 2020 . What's New According to regional health authorities, more than 1,800 additional, confirmed cases (including 25 deaths) of pneumonia caused by 2019 novel coronavirus (2019-nCoV) have been reported since January 27, 2020, throughout the country, mainly in the provinces of Hubei (1,291), Guangdong (207), Zhejiang (173), Henan (168), and Hunan (143) and in the cities of Chongqing (132), Beijing (19), and Shanghai (13). Most new cases had a travel history to Wuhan. Almost all the recent deaths occurred in Hubei Province. Twenty more patients have recovered and been discharged. More than 4,600 confirmed cases (including> 100 deaths) have occurred since December 8, 2019. A total of 13 additional, exported, confirmed cases have been reported (through January 28 , 2:00 p.m. EST) since Monday, January 27. More than 25 cases have been exported in the past 7 days. Cases reported since Monday arrived in the following countries on the dates shown: Singapore (January 19 and 23), Taiwan (January 22), Japan (January 20 and 21 ), France (arrival date unknown), and Thailand (arrival dates unknown) . All of these cases had travel history to Wuhan or contact with an ill person from Wuhan while in China. In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany , all 4 cases had close contact in a business seminar with an apparently asymptomatic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23, and she was later confirmed to have 2019-nCoV. Incubation periods in these cases have been as short as 3 days. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified . Updated travel advisories include: 1) Australia: reconsider travel to China; 2) Canada: avoid all travel to Hubei Province; 3) Finland: avoid nonessential travel to Hubei Province ; 4) France: avoid all travel to Hubei Province; 5) Germany: avoid nonessential travel to China and avoid all travel to Hubei Province; 6) India: avoid all nonessential travel to China; 7) New Zealand: avoid all travel to Hubei Province; 8) Taiwan: avoid all nonessential travel to China . Singapore now denies entry to residents of Hubei Province and those who have traveled there in the past 14 days. Mongolia and 3 regions (Amur Oblast, Khabarovsk Krai, Jewish Autonomous Oblast) in Far Eastern Federal District, Russia have closed their land borders with China . Bangladesh, Canada , India, Kazakhstan, Russia, and South Korea are arranging flights to repatriate their respective citizens from Wuhan. These persons will be closely monitored and present little threat of onward transmission. NIH-002130 All tourist attractions in Tibet Autonomous Region have been closed. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain. Overall Risk Assessment The epidemic in China is months from peaking. A report indicates that just prior to the cordoning off of Wuhan, over 5 million residents (many potentially infectious) left for other parts of China, and many thousands left for Hong Kong, Singapore, Thailand, and Japan. Exported cases have so far been to countries likely to be capable of controlling (but not preventing) ongoing transmission, which will inevitably occur. In light of the secondary cases in Germany in a business setting, the most cautious approach of having arrivals stay at home or in a hotel for 14 days after their last possible exposure in China is increasingly justified. Based on increasing data on virology, clinical presentation , and transmission, this coronavirus closely resembles SARS-CoV in many behaviors. Fortunately, sequential sequencing of viral isolates over time indicates no significant new viral mutations; mutations often increase transmission or virulence. WHO assesses the risk of this event to be very high in China , high at the regional level , and high at the global level. The closing of Wuhan airport and the major cities of Hubei province have yet to stem the flow of exported cases. The originally implicated animal market , now closed indefinitely , bears little relevance to the ongoing situation. Whether the market was the focus of a species jump from animals to humans or merely one of multiple amplification settings for initial cases is increasingly unclear . The degree of human-to-human spread outside of Hubei province remains unclear. A reproductive number, Ro, is estimated at 1.42.5 by Chinese authorities and up to 5.5 by other scientists . An Ro greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. The spectrum of disease manifestations in a large cohort study has yet to be disclosed; a severe case rate of 20% has been consistent. The existence of mildly symptomatic and asymptomatic infectious cases could increase the risk of global spread . Case fatality is impossible to ascertain at present , and lesser or greater clinical virulence compared to MERS-CoV or SARS-CoV remains speculative . Current Disease Situation More than 4,600 confirmed cases (976 severe and critical cases and 106 deaths) have occurred since December 8, 2019, in the provinces of Hubei (> 2,700; mainly in Wuhan), Guangdong (207), Zhejiang (173), Henan (168), Hunan (143), and Anhui (106) ; in the cities of Chongqing (132), Beijing (91 ), and Shanghai (66); and in 21 other provinces throughout the country. An additional 6,900 suspected cases have been reported since January 21, 2020. In the setting of a large outbreak and with increased delays in testing, a high proportion of suspected cases will evolve into confirmed cases. Seventy-nine cases have been discharged. Two-thirds of the cases are male. The youngest case is 10 years old and the oldest is 89; more than 70% of cases are over 40 years old, but the co-morbidity profiles of most cases are unknown . NIH-002131 The number of persons becoming infected with the virus has been doubling every six days. The outbreak in China is not approaching peak, and modeling indicates that is months away. Exported Cases Seventy-seven imported cases of 2019-nCoV (confirmed after arrival) presented at international ports of entry January 6-25 in 16 countries. Of these cases, more than 25 cases arrived in the past 7 days. All 77 cases had exposure in Wuhan or exposure to ill persons from Wuhan in China and symptom onset dates after December 31, 2019; none had visited the implicated market. Australia (5 cases): One case traveled while asymptomatic aboard China Southern Airlines flight CZ231 to Melbourne, Victoria State on January 19 and was hospitalized on January 23. Contact tracing is underway ; movement around Melbourne was limited prior to isolation. The remaining 4 cases traveled while asymptomatic aboard flights to Sydney , New South Wales State on January 6, 18, 20, and 23, and were hospitalized on January 15, 20, and 24. One of the patients had limited movement around Sydney prior to isolation; movement history for the other 3 cases is unknown. Cambodia (1 case): The case traveled while asymptomatic to the city of Sihanoukville on January 23, 2020, and developed symptoms on January 25. Canada (2 cases): Both cases (a couple) traveled aboard China Southern Airlines flight CZ311 to Toronto, Ontario Province on January 22. The first case was symptomatic while traveling and was hospitalized on January 23. The second case was under self-isolation and was confirmed on January 27. Contact tracing is underway; patient movement around Toronto was limited prior to isolation . France (4 cases): Two cases traveled while asymptomatic aboard a flight to Paris on January 18, and 1 case traveled aboard a flight to Bordeaux on January 22. Travel history for the fourth case in unknown. All cases were hospitalized. Hong Kong (8 cases): Three cases traveled while symptomatic on January 19 and 25; the first aboard a train to West Kowloon , the second aboard a flight to Hong Kong International Airport , and the third to Lo Wu Control Point. Four of the cases traveled while asymptomatic aboard trains on January 19 and 22. The last case traveled with diminished symptoms aboard a train on January 23. All cases were hospitalized . Japan (6 cases): Two cases traveled while symptomatic; the first aboard a flight to Kanagawa Prefecture on January 6 and the second aboard a flight to Tokyo on January 19. The first was hospitalized on January 10 and discharged on January 15 following recovery, and the second was hospitalized on January 22. Another 2 cases traveled while asymptomatic: the first aboard a flight to Tokyo on January 18 and the second aboard a flight to Aichi Prefecture on January 22. The first was hospitalized on January 23, and the second was hospitalized on January 24. The remaining 2 cases arrived on January 20 and 21 in Aichi and Tokyo prefectures. Macau (7 cases): The first case traveled while asymptomatic aboard a train and a bus on January 19, and the second case traveled while symptomatic (travel method unknown) on January 22. The first case was hospitalized on January 19 and the second NIH-002132 case on January 2 1. The third case traveled aboard a ferry on January 23 and was immediately hospitalized. Three cases traveled (methods unknown) on January 22; all were hospitalized. The last case traveled while asymptomatic on January 23 and was hospitalized January 27. Ma laysia (4 cases) : The first case traveled while asymptomatic aboard a bus to Johar Baharu on January 22 and was hospitalized on January 23. The remaining 3 cases traveled (method unknown) to Johar Baharu on January 23; all were hospitalized . Nepal (1 case): The case traveled to Kathmandu on January 5, was hospitalized on January 13, and was discharged on January 17 following recovery. Singapo re (7 cases): All 7 cases traveled while asymptomatic aboard flights on January 18, 19, 20, 21, 22, and 23. South Korea (4 cases): Two cases traveled while symptomatic to lncheon International Airport and to Gimpo International Airport on January 19 and 23, and both were immediately hospitalized. The remaining cases traveled while asymptomatic on January 20 and were hospitalized on January 25. Sri Lanka (1 case): The case traveled while asymptomatic on January 29, 2020, and developed symptoms on January 25. Taiwan (7 cases) : The cases arrived on January 20, 21, 22, and 25; at least 3 cases arrived at Taiwan Taoyuan International Airport. Thailand (14 cases): Three cases traveled while symptomatic to Suvarnabhumi Airport on January 8, 13, and 19 and were hospitalized; the travel history of the fourth case is unknown. The fifth case traveled to Bangkok on January 21 and was hospitalized on January 23. The travel histories of the remaining 9 cases are unknown. U.S. (5 cases) : Two cases traveled while asymptomatic: the first to O'Hare Internationa l Airport on January 13 and the second to Seattle-Tacoma International Airport on January 15. The first was hospitalized several days after arrival, and the second was hospitalized on January 19. The remaining 3 cases were reported in Maricopa County , Arizona and Los Angeles and Orange counties, California ; information on the patients' travel histories are unknown. Contact tracing for all cases is underway. The first case reported limited movement around Chicago prior to hospitalization; movement history for the other 2 cases in unknown. V ietnam (1 case): The case arrived in Hanoi on January 13 and was hospitalized on January 22 in Ho Chi Minh City . In addition to these exported cases , 7 locally acquired cases have been reported since Monday in Germany (4), Japan, Taiwan, and Vietnam. The cases in Japan , Taiwan, and Vietnam reported contact with an obviously ill person from China. In Germany, all 4 cases had close contact in a business seminar with an apparently asymptoma tic Chinese woman on January 21 (who previously had contact with relatives from Wuhan); the woman states symptom onset was on a flight to Shanghai on January 23 , and she was later confirmed to have 2019-nCoV . Incubation periods in these cases have been as short as 3 days. Entry/Exit Screening NIH-002133 In a reversal of long-standing policy , WHO now recommends that all countries implement temperature screening at points of entry for passengers arriving from 2019nCoV-affected countries. Screening should be accompanied by dissemination of riskcommunication messages at points of entry to later capture asymptomatic persons who are in the incubation phase. In early January , some exit screening was implemented at Wuhan Tianhe International Airport (nonstop flights to Istanbul , London, New York , Osaka , Paris, Rome, San Francisco , Tokyo, and major hubs throughout Southeast Asia) , as well as at 3 major rail stations in Wuhan . More restrictive screening was instituted on January 15 in Hubei until cessation of international flights on January 23. Despite exit screening at all international airports in China in the past week, significant numbers of cases continue to be exported. Entry screening at international ports of entry has been or is being implemented as noted below , and anyone with fever and respiratory symptoms who has been to 2019nCoV-affected areas in the previous 14 days will be detained and isolated at these locations: Algeria: Houari Boumediene Airport, Mohamed Boudiaf International Airport , Oran Ahmed Ben Balla Airport Burma (Myanmar) : Yangon International Airport Egypt: Cairo International Airport (all flights from China) Hong Kong : All border checkpoints , including Hong Kong Internationa l Airport and the railway station in West Kowloon India : Bengaluru , Chennai, Delhi, Hyderabad , Kochi, Kolkata, and Mumbai international airports (all flights from China and Hong Kong) Italy: Leonardo da Vinci-Fiumicino Airport Iran: Teh ran Imam Khomeini International Airport (all flights from China) Macau : Macau International Airport North Macedonia: Skopje International Airport (connect ing flights from Asia) Qatar: Hamad International Airport (all flights from China) Russia: Moscow, Irkutsk Oblast , and Yekaterinburg international airports and points of entry in Amur Oblast Singapore : Changi Airport South Africa : O.R. Tambo International Airport (all flights from China) South Korea : lncheon International Airport Taiwan: All international airports NIH-002134 Thailand : Krabi , Suvarnabhumi, Don Mueang , Phuket , and Chiang Mai airports Turkey: All international airports (all flights from China) United Arab Emirates: Abu Dhabi International Airport and Dubai International Airport (all flights from China) U.K.: Heathrow International Airport U.S.: Twenty points of entry, including Hartsfield -Jackson Atlanta International Airport, John F. Kennedy International Airport, Los Angeles International Airport , O'Hare International Airport , and San Francisco International Airport. Travelers from Wuhan may have their temperatures taken and/or be required to complete a symptom quest ionnaire; travelers with symptoms (fever , cough , difficulty breathing) will be deta ined for additional assessment. Australia, Bahrain, Bangladesh, Belarus, Canada, Cote d'Ivoire, Ghana, Indonesia, Japan, Kazakhstan, Kenya, Kyrgyzstan, Madagascar, Malaysia, Nepal, Nigeria, North Korea, Philippines, Saudi Arabia, Serbia, Senegal, Sri Lanka, Tajikistan, Tunisia, Vietnam : Airports and other ports of entry Travel Advisories The following countries and/or organizations have published travel recommendations: Avoid All Travel to Hubei Province: Australia , Canada, China (see below) , France , Germany , Japan, Mexico , New Zealand , U.K., U.S. Avoid Nonessential Travel to Hubei Province: Finland, Ukraine Avoid All Travel to China : None at present Avoid Nonessential Travel to China : Australia, Germany, India , Taiwan , U.S. No Advisory: WHO Travel Restrictions Different levels of travel restrictions are in effect: No Flights from China: Finnair Airlines (flights from Beijing and Nanjing), Air Seoul No Flights from Wuhan: Wuhan Airport is closed to all international and domestic flights. Land Borders with China Closed : Kyrgyzstan , Mongolia , North Korea , Russia (Amur Oblast , Khabarovsk Krai , Jewish Autonomous Oblast in Far Eastern Federal District) ; high speed rails and ferry services suspended in Hong Kong No Residents from Hubei Province: Hong Kong, Macau, and Singapore (including visitors in past 14 days), Malaysia , and Taiwan NIH-002135 Internal Travel Restrictions in China: Major cities in Hubei Province have instituted a travel ban on occupants of their cities, suspending urban buses, subways , ferries , and long-distance passenger transport from the cities, including flights and trains , and closing intercity roads. lnterprovince shuttle buses in major areas have stopped. Many bars, restaurants, shops, and museums are closed in Hubei Province, Guangdong , and many other affected areas. Major tourist attractions have closed in Beijing, Shanghai , Sanya (Hainan Province) , Hong Kong, and Tibet Autonomous Region. China has stopped all inbound and outbound tour groups but not individual travel. Internal travel for the Lunar New Year Holiday has been severely limited by the government , and public gatherings are forbidden. The reopening of schools and universities has been postponed in many areas. Shanghai has temporarily closed all nonessential workplaces. Visitors from Hubei Province will be actively monitored for 14 days in Haikou, Hainan Province. No Flights from 2019-nCoV-Affected Countries: Travelers going to Samoa must spend at least 14 days in a country free of 2019-nCoV and undergo medical clearance prior to travel to Samoa. Australia , Bangladesh, Belgium , Canada , France, Germany , India, Japan, Kazakhstan , Morocco, Netherlands, Russia, South Korea, Spain, Thailand, U.K., and U.S. are arranging flights to repatriate their respective citizens from Wuhan . These persons will be closely monitored and present little threat of onward transmission . Transmission The detailed epidemiology of possible causative animal exposures and zoonotic transmiss ion remains unclear. Many (27 of 41) earlier cases were directly linked to South China Seafood City market in Jianghan District, which sold seafood and other wildlife (including birds). More than 580 environmental samples , without indication as to whether animal tissue was included , were collected from the implicated market. Of these , 33 tested positive for 2019-nCoV , indicating that the market was an-or the-origin point of the large-scale outbreak. Thirty-one of the positive samples (94%) were collected from the western part of the market, where wildlife was traded. The first published epi-curve shows that the symptom onset date of the first patient identified in the outbreak was December 1, 2019. The patient reported no exposure to the implicated market; no epidemiological link has been detected between this case and later cases . This finding raises the possibility of an initial jump of 2019-nCoV directly from bat to human, with subsequent initial human-to-human propagation within the seafood market. Infected intermediate animal hosts , if they exist, may still be present in the supply chain. South China Seafood City market, now closed indefinitely , remained in operation through December 31, 2019. Other points of infection would be likely because many subsequent cases had no contact with the implicated market. Chinese authorities have now stated that human-to-human transmission is in the fourth generation in Wuhan and at least the second generation elsewhere (mostly in clusters). A reproductive number, Ro, is estimated at 1.4-2.5by Chinese authorities and at up to 5.5 by some scientists. An R0 greater than 1 indicates that each case leads to more than 1 subsequent case, making control much more difficult. Ro is not a constant number and changes with the ongoing circumstances and evolution of an outbreak . One published cluster study indicates asymptomatic shedding (but not transmission) by a single patient. Sequence data from several small clusters indicate identical virus in all subjects within the cluster. NIH-002136 More than 47,800 close contacts remain under surveillance (> 1,200 have been released), and contact tracing is ongoing in affected provinces and municipalities. However, not all contacts are being ascertained or monitored adequately. As many as 16 health care workers (HCWs) have been confirmed as infected by at least 1 case in Wuhan in a potential super-spreading event, but overall infectivity for HCWs has not been established. No case of 2019-nCoV has been attributed to transmission on an aircraft . The survival rate of the virus on surfaces or in the environment is unknown. Disinfection processes that are effective for other zoonotic coronaviruses should be followed for now. Clean daily all "high-touch" surfaces, such as counters, tabletops, doorknobs, bathroom fixtures, toilets, phones, keyboards, tables, and bedside tables. Also, clean any surfaces that may have blood, bodily fluids, and/or secretions or excretions on them. Use a diluted bleach solution or a household disinfectant with a label that says "EPA-approved ." To make a bleach solution, add 15 ml (1 tablespoon) of bleach to 1 l (1 quart) of water; for a larger supply, add 60 ml (2 oz) of bleach to 4 l (1 gallon) of water. Clinical Manifestations Most cases have reportedly exhibited symptoms of fever, respiratory compromise, and bilateral pneumonia with diffuse, ground glass-like infiltrates on chest x-ray or CT scan. Unlike SARS-CoV, upper respiratory illness symptoms (rhinorrhea, sneezing, sore throat) and diarrhea are not common. Overall, about 20% of the cases have been severe or critical, including pneumonia , respiratory failure, and in some cases death. The existence of asymptomatic cases has not been ascertained. No known treatment exists for 2019-nCoV, although remdesivir will be available shortly from the U.S . CDC for compassionate use. Usual antiviral drugs, including oseltamivir (Tamiflu), baloxavir, ribavirin, and acyclovir, are ineffective. Steroids should not be used. Based on earlier literature , the combined use of lopinavir and ritonavir is under study in China. Current influenza vaccination is recommended to decrease the risk of simple influenza being mistaken for 2019-nCoV upon return. In a small cohort of 41 patients (median age was 49 years; interquartile range: 41-58) conducted early in the epidemic (presentation before January 2), the most common symptoms at onset of illness were fever (98%), cough (76%), and myalgia or fatigue (44%). Dyspnea developed in 55% of patients at a median of 8 days. All cases except 1 had bilateral pneumonia. Milder cases had chest CTs that showed bilateral groundglass opacity with subsegmental areas of consolidation, whereas ICU patients had bilateral lobar and subsegmental areas of consolidation . Only 66% of cases (even in this early cohort) had been exposed to the South China Seafood City market. The casefatality rate was estimated to be 15%, but more severe cases tend to predominate early in an epidemic. Limited data from another published cluster study indicate a 3- to 6-day incubation period similar to SARS-CoV and clinical and radiologic features similar to SARS-CoV cases in 2003. Another report indicates an incubation period ranging from 1 to 14 days. Virology 2019-nCoV was initially isolated from 1 case and entirely sequenced; this information was published internationally by Chinese scientists on January 10. Electron microscopy of 1 specimen demonstrated classic coronavirus particles. 2019-nCoV is the seventh NIH-002137 member of the family of coronaviruses that infect humans . Novel coronaviruses from Wuhan , together with 2 bat-derived SARS-like strains, form a distinct clade in lineage B of the subgenus sarbecovirus. 2019-nCov is a group 2b coronavirus (as are MERS-CoV and SARS-CoV), with a whole genome similarity of up to 80% to SARS-CoV but with a similarity between different gene segments ranging from 60% to 90%. 2019-nCoV exhibits a 96.5% similarity to the known bat coronavirus precursors in the same viral clade. Sequence data allowed national laboratories to rapidly develop diagnostic kits, which are now available in most developed countries and most Asian countries. HKU1, NL63, 229E , and OC43 are human coronaviruses that are detected by some routine multiplex PCR panels used in routine clinical practice . These coronaviruses are associated with minor upper respiratory infections and viral pneumonia, but unlike SARS-CoV , MERSCoV, and 2019-nCoV , these agents are not associated with major outbreaks or severe respiratory distress syndrome. 2019-nCoV is not reactive in these tests . The findings so far strongly favor (but do not prove) causation. 2019-nCoV has been shown to use the same cell-entry receptor as SARS-CoV. Viral loads appear to be highest in lower respiratory tract specimens, which should be the primary specimen obtained. Prediction of human-to -human transmissibility from sequence data is difficult because coronaviruses vary widely in their transmissibility; coronaviruses acquired from animals generally have some potential for human-to-human transmission. Evidence from subsequent whole genome sequences acquired over the last several weeks show little genetic variation, indicating that the virus jumped from an animal reservoir to humans within the last few months. Identical recent mutations in epidemiologically unlinked cases support sustained human-to-human transmission. Criteria for Testing of Suspected Cases U.S. CDC Persons meeting the following criteria (clinical features and epidemiologic risk) for suspected cases of 2019-nCoV will be considered persons under investigation (PUI): • • Fever and symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus a history of travel to Wuhan or close contact with a PUI for 2019-nCoV while that person was ill in the past 14 days before symptom onset Fever or symptoms of lower respiratory illness (e.g., cough, shortness of breath) plus close contact with an ill, laboratory-confirmed 2019-nCoV case in the past 14 days before symptom onset HCWs entering the room with a PUI should use standard precautions, contact precautions , airborne precautions , and eye protection (e.g., goggles or a face shield). PUis for 2019-nCoV should be asked to wear a surgical mask as soon as they are identified and be evaluated in a private room with the door closed, ideally an airborneinfection isolation room if available. Prevention Travelers going to Wuhan should avoid animals (alive or dead), animal markets, products that come from animals (such as uncooked meat), and contact with illappearing persons. Quality of infection control at medical facilities in Wuhan is uncertain , and those with minor medical problems should avoid busy medical settings. NIH-002138 Infection control supplies have been depleted in medical facilities in the smaller cities in central China; the situation is critical in many areas and resupply is uncertain . Travelers who develop fever and respiratory symptoms within 14 days of travel to Wuhan should immediately be isolated, and public health authorities should be alerted. Employees , Students , Visitors , All Others Coming from Wuhan Whether asymptomatic individuals infected with 2019-nCoV are infectious to others is unknown. Influenza viruses can be transmitted 1 to 2 days prior to symptom onset. SARS-CoV did not transmit until 4 days after symptom onset, which led to its eradication because all contacts with fever could be promptly identified and isolated . If 2019-nCoV is similar to SARS-CoV , asymptomatic arrivals from Wuhan should selfmonitor by taking a temperature reading immediately prior to coming into the workplace or school for 14 days after their last exposure in Wuhan. Arrivals with fever at any time should self-report to public health authorities (or telephone ahead before presenting to a hospital) and should wear a mask as soon as possible. A more stringent approach would require that an employee, student, or visitor-upon arrival to a workplace or school- be instructed to perform an additional temperature check in the presence of medical personnel to ensure compliance with local self-monitoring requirements. In addition , prior to any gathering of~ 2 persons , attendees could be required to perform additional self-monitoring . Based on advanced information and employee or visitor medical screening, additional preventive measures may be required (e.g. , increased ventilation, larger meeting rooms with more personal space per participant , disinfection of work areas and lavatories, and provision of alcohol wipes). The most cautious approach would be for arrivals to stay at home or in a hotel for 14 days after their last possible exposure in China . To date, all known cases exported to other countries had either visited Wuhan or had contact with an ill person from Wuhan while in China . Sent from my magical iPad! On Jan 29, 2020, at 2:46 PM, Richard Tubb wrote: Richard J. Tubb, MD Brigadier General (retired) White House Physician Emeritus NIH-002139 From: Date: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 04:03:31 +0000 Howard Bauchner Conrad, Patricia (NIH/NIAID) [El To: Cc: Subjec t: RE: Study+claiming+new+coronavirus+can +be+transmitted+by+people+without+symptoms+was+flawed Thanks, Howard. Talk soon. -----Original Message----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:37 AM To: Fauci , Anthony (NTTI/NIAID) [E] Cc: Conrad , Patric ia (NJH/NIA ID) [E] -----,,-----,----..,... Subject: RE: Study+claim ing+new+coronavi rus+can+be+t ran smi tted+by +peopl e+ w ithout+ symptom s+was+ fl awed ------~~ The author of our case-series - proof today will send to you - is an ICU do c in Wuhan - trained with Derek Angus he has been great - but I have asked him about himself, bis family - we loss track of the personal - wh ich is so important. J have had a few "emergencies" like this - at BCH - with Jerry Klein - some infect ious disea se outbreaks; a couple major car accidents; etc. A lso worked at the Berhorst Clin ic in Gua temala in 1978 (before there was global health) numerous 5-l 0-15 people emergencies - always end though - for you this is the pandemic that never sto ps giving. Try to take a break; have a good glass of Claret on me . HC B ----- Original Message ----From: Fauci , Anthony (NTH/NIAID) [E] (b) (6)> Date: Wedne sday , February 05 , 2020 5:3 1 AM To: How ard Bauchner Cc: Co nrad , Patric ia (NIH/NIAJD) [E] (b) (6) > Subject: RE: Study+claiming+new+coronavirus +can+be + transmitted+by +people +without+ symptoms +was +flawed [Warning External Email) Howard: Your outline look s fine. Am hangi ng in there. Feels like my intern ship and first year residency when I was on eve ry other night and every other weekend, hut actually never left the hospital because the patients were so sick. Best, Tony ----- Original Messag e----From: Howard Bauchner Date: Wednesday , February 5, 2020 6:23 AM To: Fauci, Anthon y (NIH/NIAID) [E] CbH Subject: RE: Study+claiming+new+corona virus +can+be +transmitted+by +people +without+symptoms +was +flawed --------, a-s-r,= L ikely come up tomorrow in our discussio n - not NEJM pape r but just the concept. Outline if OK with you NIH-002 140 What's up in China What's up around the world What's up in US And then more specific questions ls this more like HIN! than MERS Can we really know mortality risk (denom inator problem). Incubation period How "infectious" News on treatment Quarantine working Sound OK? You surviving - worried a bit about your workload. HCB -----Original Message- ---Fro m: Fa uci , Anthony (NTH/NlAID)[E] (b)(6) > Date: Wednesday, February 05 , 2020 5:20 AM To: Howard Bauchner Subject: RE : Srudy +claimi ng+new+corona virus+can+be+ transm itted+by+people +without +symptoms +was+tlawed [Warning External Emai l] The paper was flawed, Embarrassment for NEJM . However, the concept is correct. Spoke in detail to the Director of the Chinese CDC (confidential) and they are seeing asymptomatic transmission (low level) in China. -----Original Message----From: Howard Bauchner < Howard .Bau chner@jamanetvvork .org> Date: Wednesday, February 5, 2020 6:15 AM To: Fauci , Anthony (NlH/NlAID) [E] (b)(6) > Subject: FW: Study +claiming+new+coronavirus+can +be+transmitted +by+people+without+symptoms+was+flawed ------~-= Tony Suspect you saw this. Big problem if true - rushin g to publication - leads to big mistakes. HCB ------ --:;;=a<, -----Original Mcssage ----From: Redberg, Rita (b) ( Date: Wednesday , February 05 , 2020 5: 13 AM NIH-002141 To: Howard Bauchner ; Phil Fontanarosa Subject: Study+claiming+new +coronavirus +can+be+transmitted+by+people+withou t+symptoms+was+flawed [Warning External Email] Assume you saw, but. hltps ://urldcfense .proofi?oint.com/v2/url?u=h ttps-3A www.sc iencemag .org news 2020 02 paper-2Dnon 2Dsymp tomatic-2Dpatient-2Dtransmitting-2Dcoronaviru s2Dwrong& d=DwIF Ag&c=iqcSL Yk:BTKTEV8nJYtdW A&r=Cp YvDJwpp PNcFU Z7y8a6zr8BltWA4gtfR WytiK tF o VM&m=4xruNHF PsXovM miMLZWiD9OzCN hiiGOKmt HhrZcP8c&s=afNfNjVB5x iV3y8BiCPHkwB nAiRXsktAbH l rM9a3j PY&e= NIH-002142 From: Fauci, Anthony (NIH/ NIAIO) [E) Thu, 6 Feb 2020 03:59:46 +0000 (b)(6) A uchincloss, Hugh (NIH/ NIAID) [C] FW: touc hing base abou t Texas Biom ed ical Research Institut e Date: To: ----------- Subject: Please t ake care of this. From: Larry Schlesinger ----------Date: Wed nesday, February 5, 2020 8:42 AM (b)(6) To: Auchincl oss, Hugh (NIH/NIAID) [ E] ----------=- (b)'""'(= >; Fauci, Antho ny (NIH/N IAID) [E] (b)(6) Subject: to uching base about Texas Bio medical Research Insti t ute Hi Tony and Hugh. I know that I am writing to you at a busy time during yet another infectious disease outbreak that is rapidly evolving . However, I wanted to send you a brief note to update you about the transformational change going on in the landscape of our free standing institut e with its new , sharply defined goal to be the global leader in eradicating infectiou s disease threats in the world . I know that you are familiar with us. I have been leading the institute since June of 2017 and currently finishing year one of a 10 year board-approved plan of growth in our scientists , educationa l programming and campus modernization. I believe that you are aware that we house the only private BSL4 . We also just opened our newest of 5 BSL3 facilities , this newest one being nearly 8000 sq . ft. with capacity for ~100 NHPs , small animals, a complete aerosol suite and a PET CT . We also house the SNPRC, now under the leadership of Deepak Kaushal (who replaced Robert Lanford) and with the largest marmoset colony as a result of 4J restructuring our building facilities (in addition to our other species . CbH Please check out our newly designed website: www .txb iomed .org . The bottom line is that I left university life to lead an organiza tion that is determi ned to not only discover critical, new fundamental science but also effectively and efficiently bring it full forward to create portfolios for the FDA through our business model , nimbleness, regulated scienc e culture (GLP level), longstanding public and private partners through contract science (esp. BARDA) , culture and community support . NIH-002 143 We want to help! Please let us know if and how we can contribute to this outbreak and undoubtedly others going forward . I truly appreciate your leadership. The country gets the voice of reason on infectious disease outbreaks through your public efforts. I enjoyed learning more about this during my time on council. Best, Larry Larry Schlesinger, MD Professor President and CEO Texas Biomedical Research Institute 8715 W. Military Drive, San Antonio, TX 78227 Email: (b)(6) Teamwork I Integrity I Diversity I Excellence I Safety Executive assistant: (b)(~ (b) (6) ==== (b ~ )~(6) ~ Phone Mobi le --------- Email: I (b)(6)j CONFIDENTIALITYNOTICE:This e-mail and any files and/or attachments transmitted, may contain privileged and confidential information and is intended solely for the exclusive use of the individual or entity to whom it is addressed. If you are not the int ended recipient, you are hereby notified that any review, dissemination, dist ribution or copying of this e-mail and/or attachments is strictly prohibited. If you have received this e-mail in error, please immediately notify the sender stating that this transmission was misdirected; return the e-mail to sender; destroy all paper copies and delete all electronic copies from your system without disclosing its contents. NIH-002144 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/N IAID) [E) Thu, 6 Feb 2020 03:49:36 +0000 Robert Knob ler Cassett i, Cristina (NIH/N IAID) [E];Conrad, Patricia (NIH/NIAID) [El RE: Potential Approa ch to Wuhan Coronavirus Bob: Thanks for your no te. It was good to bear from you. I am copying Cr istina Cassetti on this e-mail. Cristina directs the extramural coronavirus research activities. Perhaps you two can connect to discuss research opportunities. Best, Tony -----Original Message ----From: Robert Knobler ______ ""' (b ")'""' c= --------:,,:,~ ----,----- Date: Wednesday , Febru ary 5, 2020 10:55 AM To: Fauci , Anthony (NIH/N IAJD) [E] Su~j e ct: Pote ntial Approach to Wuhan Coronavirus (b)(6) > Dea r Dr. Fauc i, You likely do not recall meeting me when J was looking at potential fellowships in 1978, however , l never forgot your enthusiasm. 1 went out to San Diego and worked with Mike Oldstone, between 1979 and 1984. l did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . l focused on genetic resistance, and eventually desc ribed a mouse locus for suscept ibility, which coded for the MHV receptor. Lacking the correct receptor or blocking binding of the virus spike protein to the receptor wi th monoclonal antibodies blocked infection . On to the prese nt problem of human coronaviruses . Vaccines will take a long time for the current crisis. The angiotensin converting enzyme 2 receptor has been identified as the relevant human coronavirus receptor in earlier studies ofSARS and MERS human corona virns outbreaks. I am writing to suggest the investigat ion of ARBs as potential block ing agents to eithe r reduce or completely block infection . Perhap s this can be checked . if correct , there may still be sufficient untainted supplies of ARBs, such as irbesartan, available, or production can be scaled up, if this truly is the eve of a pandem ic. Wishing you success in this endeavor. I am willing to cont ribute in any way l can. Please feel free to contact me by e-mail or my cell phone. Talso did do clinical trials whil e with M ike, and then when I joined the neu rology faculty of Jefferson in Phi ladelphia. I have been out on my own since Decemb er 1998, but I have never lost my interest in this work . For another tim e, I also have so me novel ideas on how HIV become s AIDS , as well. Ironica lly, the se ideas we re based upon observati ons I made during my analy sis ofMHV. All the Best , Rober t L Knobler, MD, PhD (b)(6) NIH-002 147 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 03:28:54 +0000 Cohen, Elizabeth RE:treatment protocols The Chinese are putting together protoco ls to test certain drugs such as remdesivir. From: Cohen, Eli zabeth Se nt: Wednesday, February 5, 2020 3:19 PM To: Fauci, Anthony (NIH/NIAID) [E]-------=- (b) c-c (= > Subject: treatment protocols Hi Tony, We were wondering if there are any part icular protocols being suggested for treating the Wuhan coronavirus cases in the US. Are there discussions among the teams caring for these patien ts about the best approach? Many thanks. Best, Elizabeth Elizabeth Cohen, MPH CNN Senior Medical Correspondent NIH-002 148 Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 02:54:42 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: Corona virus/sepsis treatment Attachment s: CBR Baum Satz (5) .pdf, Kim Brechbiel Satz.pdf, Kim supplement-01.doc, REFERENCES Corona Virus .docx From: Date: Please handle. From: stanley satz (b)(6) Date: Wednesday, February 5, 2020 7:20 PM To: Fauci, Anthony (NIH/NIAID) [E] -----== _______ _. (b)(6)> Subject: Corona virus/sepsis treatment Dear Dr. Fauci, (b) (4) NIH-002150 (b) (4) Best regar ds, Stanley Satz, Ph.D. Chairman and Chief Scientific Officer Advanced Innovativ e Partners, Inc . Professor, Florida Atlantic University, Universi ty of Miami School of Medicine www .advanced innovativepartners .com www .bionucleo nics.com (b)(6) Confidentiality Notice This message is being sent by or on behalf of Dr. Satz. It is intended exclusively for the individual or entity to which it is addressed . This communication may contain information that is proprietary, privileged or confidential or otherwise legally exempt from disclosure. If you are not the named addressee, you are not authorized to read, print, retain, copy or disseminate this message or any part of it. If you have received this message in error, please notify the sender immediately by e-mail and delete all copies of the message. NIH-002151 From: Date: To: Cc: Subject: Feb 2020 Attachments: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:54:19 +0000 Conrad, Patricia (NIH/NIAID) [E) Haskins, Melinda (NIH/NIAID) [E];Billet, Courtney (NIH/NIAID) [El FW: Dr. Levitt summar izes CDC2019-nCoV Committee Report released today 5 M and M Wuhan Virus .pdf See me about getting someone to prepare a response. From: Robert Levitt (b)(6b Date: Wednesday, February 5, 2020 7:50 PM To: Azar, Alex (OS/10S ) (b)(6)> ; Fauci, Anthony (NIH/NIA ID) [E) Subject: Dr. Levitt summarizes CDC 2019-nCoV Committee Report released today 5 Feb 2020 -------- (b)(6) Dear Secretary Azar and Dr. Fauci, I have read carefully the CDC's report issued this morning on the Wuhan virus (2019-nCoV) epidemic originating in Wuhan, Hubei Prov ince, PRC. The Report was prepared by CDC's best Ph.D.s, M.D.s, and D.V.M.s See the pdf attached above for the complete report. Below I have recorded what I think the most important facts in the report for Secretary Azar and other federal officials who must stop the spread of 2019-nCoV in the U.S. by identifying all infected persons and their contacts . I have also added my personal thoughts on how to stop t he spread of this novel coronavirus and a persona l fear I have communicated in the past: to Secretary Azar -- President Trump signed an order preventing entry into the U.S. of any person who has trave led to mai n land China (PRC). Exceptions in clude U.S. citizens and permanent residents and t heir famil ies. Thank you Mr. Trump. -- CDC maintains an office in the PRC. So info rmat ion from Wuhan, Hubei, PRC, shou ld be 'r eal t ime'. -- Enhanced screening of persons entering the U.S. is taking place at 18 ports and 5 airport s. The number of ports and especia lly airports needs to be increased. The Report states that 14 ,000 Chinese enter the U .S. daily. If the 5 airports receive 85% of these Chinese, then 2,1 00 Chinese enter the U .S. daily at other airports without enhanced screening. -- CDChas developed its own RT-PCRtest to detect 2019-nCoV in respiratory specimens. I have read case reports where state laboratories have required too much proof of suspected Wuhan virus from clinicians before perfo rming RT-PCRtesting of specimens . CDC should provide their improved RT-PCR test to all states and HHS should insure that all states have sufficient equipment and trained personnel for rapid turn-around time. NIH-002 152 -- CDChas grown the 2019-nCoV virus. CDC should expedite distribution of the grown virus to researchers with verified credentials and vetting in a safe and monitored procedure. -- CDC recommends that persons suspected by clinicians of having 2019-nCoV be placed in a separate room with a N95 face mask so that they are not in range of other patients. HCW should wear personal protection: gloves, gown, face shield or N95 mask and goggles. -- Clinicians have identified 8 of the current 11 patients infected with 2019-nCoV in the U.S. CDC is doing a terrific job in getting the message out to clinicians and the public. Sent from Outlook NIH-002153 From: Date: Fauci, Anthony (NIH/NIAIO) [E) To: Thu, 6 Feb 2020 00:56:18 +0000 Mak, Tak Cc: Subject: Cassetti , Cristina {NIH/NIAID) [E];Conrad, Patricia {NIH/NIAID) [E] RE:An Idea Tak: Thanks for the note . It likely w ill be more efficient if I refer you to the program people in my Institute who could go over these data with you and then get me involved later . The reason that is tha t I am doing 18 hours pe day (seriously) as part of the White House Task Force and it would very difficult for me to fit in a meeting to go over data. I have copied Dr. Cristina Cassetti who runs our coronavirus extramural research program . I will ask her by this e-mail to contact you to have our people discuss your work with you. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone Cb) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Mak, Tak (b)(6) Date: Wednesday, February 5, 2020 7:30 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: An Idea -------=-,--=, -------- (b)(6) Dear Tony, It has been a while since we discussed science. (b) (4) (b) (4) NIH-002 155 (b)(4) Best regards, Tak This e-mail may contain confidential and/or privileged informat ion for the sole use of the intended recipient. Any review or distribution by anyone other than the person for whom it was originally intended is strictly prohibited. If you have received this e-mai l in error, please contact the sender and delete all copies. Opinions, conclusions or other information contained in this e-mail may not be that of the organ ization. If you feel you have received an email from UHN of a commercial nature and would like to be removed from the sender's mailing list please do one of the following : (1) Follow any unsubscribe process the sender has included in their email (2) Where no unsubscribe process has been included, reply to the sender and type "unsubscribe" in the subject line. If you require additional information please go to our UHN Newsletters and Mailing Lists page. Please note that we are unable to automatically unsubscribe individuals from all UHN mailing lists. NIH-002156 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 00:00:36 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El Josie Golding;Tabak, Lawrence (NIH/OD) [El RE: Prevalence of infect ion and stage of the epidemic in Wuhan Jeremy: I left out an important name for the coro naviru s evolution working group. Please include her: Pardis Sabeti at the Broad Institute of MIT and Harvard Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phone: (b)(6) FAX : (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fauci, Anthony (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 5:25 PM To: Jeremy Farrar (b)(6)>; Collins, Francis (NIH/OD) [E] Cc: Josie Golding (b)( >; Tabak, Lawrence (NIH/OD) (E] ------- (b)(6) (b)(6) Subject: RE: Prevalence of infection and stage of the epidemic in Wuhan Jeremy: Thanks for the note. Looks like things are moving along with WHO. I will list below a number of names for potential members of the working group to examine the evolutionary origin of the 2019-nCoV in addition to the individuals who were on the call with us last Saturday: Harold Vannus - Weill Cornell Medical Center - New York City Feng Zhang - MIT (CRISPR expe11) Joseph DeRisi- Chan Zuckerberg (CZ) BioHub (he's paying close attention to the Wuhan strain vs other bat viruses and the SARS virus) NIH-002157 Don Ganem - University of California at San Francisco (UCSF) and the CZ BioHub (knows more about hepadnaviru ses but an outstanding clinical and basic viro logist) John Coffin - Tufts and National Cancer Institute , NIH (worked out the confusion over the alleged Chronic Fat igue Syndrome retrovirus that proved to be a xenotropic MLV) Eugene Koonin - NCBI/National Libreary of Medicine , NIH; ht1ps://www.ncbi .nlm .nih.gov/research/groups/koon in/) Wayne Hendrickson - Columbia University and the New York Structura l Biology Center Gary Nabel - Sano:fi (Boston) Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jeremy Farrar (b)(6) Sen t: Wednesday, February 5, 2020 6:21 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-:)(-== 6); Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Josie Golding (b)(6) Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Francis and Tony Couple of things: • I spoke again with WHO this morning. I believe they have listened and acted. Let me know if you agree o At the WHO meeting next week they will set up the Group who will "look at the origins and evolution of 2019n-CoV" o They have asked for names to sit on that Group - please do send any names NIH-002 158 o We can have a call this week with a core group of that to frame the work of the Group includ ing - if you could join? o I think this puts it under the umbrella of WHO, with action this week and into next o With names to be put forward into the Group from us and pressure on this group from your and our teams next wee k. • The team will update the draft today and I will forward immediate ly -they will add further comments on the glycans Does that sound reasonable to you? Jeremy --------- (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, 4 February 2020 at 13:18 To: Francis Collins CbH6)>, Jeremy Farrar Subject: RE:Prevalence of infect io n and stage of the epidemic in Wuhan ----------- ?7 (b)(6) (b) (4) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Bu ilding 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892 -2520 Phone : (b)(6) FAX: (301) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ________ .. From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Tuesday, February 4, 2020 6:12 AM To: Jeremy Farrar (b)(6) Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: RE:Prevalence of inf ection and stage of the epidemic in Wuhan Yes, --------------------------------- Francis NIH-002159 (b) (4) From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 6:08 AM To: Collins, Francis (NIH/OD) [E] (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan -----~~ (b) (4) On 4 Feb 2020, at 10:58, Collins, Francis (NIH/OD) [El Very thoughtful ------- (bH > wrote: (b)(4) (b) (4) analysis. Francis From: Jeremy Farrar (b)(6) Date: Tuesday, February 4, 2020 2:01 AM To: Fauci, Anthony (NIH/NIAID) [El --------=-<-=Collins, Francis (NIH/OD) [E) (b)(6J>; (b)(6) Subject: FW: Prevalence of infection and stage of the epidemic in Wuhan Pleasetreat in confidence - a very rough first draft from Eddie and team - they will send on the edited , cleaner version later . Pushing WHO again today From: Edward Holmes (b)(6J> Date: Tuesday, 4 February 2020 at 06 :33 To: Jeremy Farrar (b)(6J> Subject: Re: Prevalence of infection and stage of the epidemic in Wuhan Here's our summary so far . Will be edited further. It's fu ndamental science and completely neutral as written. Did not mention other anomalies as this will make us look like loons. As it stands it is excellent basic science I think, which is a service in itself. NIH-002160 Will finish as soon as we can. PROFESSOREDWARDC. HOLMES FAA FRS ARC AustralianLaureate Fellow THE UNIVERSITY OF SYDNEY Marie Bashir Institutefor Infectious Diseases & Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of Sydney I Sydney I NSW 120061Australia (b)(6) (b)( NIH-002161 Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 20:52:29 +0000 From: Date: To: Conrad, Patricia (NIH/NIAID) [E) FW: note to Patty -- and Tony Fauci Subject: Let us discuss. Steve is a good guy, but I do not want to kill myse lf trying to do too many thingsdat the same time . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . --------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Wednesday, February 5, 2020 3:27 PM To: NIAID OD AM Subject: FW: note to Patty-- and Tony Fauci Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectious Diseases The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaime r: The information in this e-mail and any of its attachmen ts is confidential and may contain sensitive info rma tion. It shOuld not be used by anyone who is not the original intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it NIH-002164 from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. From: Steve Clemons Date: Wednesday, February 5, 2020 3:20 PM To: Conrad, Patricia (NIH/NIAID) [E)________________ -----------------~= Cb _H_6) Subject: note to Patty -- and Tony Fauci Greetings Patty and Tony -- I see you on TV constantly guiding us through the terrain on our preparedness fo r outbreaks such as what we have seen in China. I want to see if I can add one more request to your pile to think about.. ..and I am trying to see if what I am suggesting might work right before your Aspen talk next Tuesday at noon. In addit ion to my great role at The Hill, I am host of a new show called "The Bottom Line" on Al Jazeera English that runs four times a week on thei r global network and is garnering between 100k-200k views a week on YouTube in the US. The show is doing really well and is a 24 minute panel discussion of three experts on a single topic that I facilitate. I would love to have you, Tony, be the anchor commentator on what we should do not only on the coronavirus but in general on the infrastructure of pandemic preparedness in the country -- sort of a shorter form of that great PBSshow you did called Invisible Killers. We would want to tape in our studio at 21st and M Streets NW from 11:00 am - 11:30 am (we don' t go over), or I could move it 15 to 30 minutes earlier if you like next Tuesday, 11 February. I know you have t o be at Aspen at noon {I was invited too) -- so I could take yo u if you like. I realize that this may be too much. -- but in these times, I t hink it's important to get smart commentary and analysis out there -- and I think I can add a couple hundred thousand eyeballs and ears to the millions you are already reaching. The producers are also able to provide car and driver (b)( 4) (b) (4) Hope this might work my frie nd . I may send a short form of this to your cell phone. Call me if you want to chat, eit her of you, at ----- (b) (6). a II best, STEVE Steve Clemons Editor at Large, The Hill 1625 K Street NW, Suite 900 Washington, DC 20006 Tel: .,.1.202.628.8500 Cell: (6) TheHlll.com Email: SClemons@TheHill.com Follow me on Twitter @SCCl emons NIH-002165 From: Date: To: Subject: (b)(6) Wed, 5 Feb 2020 10:33:15 -0500 Conrad, Patricia (NIH/NIAID) [E] Fwd: NTV Broadcasting Interview Request FYI Begin forwarded message: From: Cecpep6eKOB Xa,1l) Ku-MypaTKapaxaHOBHq Date: Fehmary 5, 2020 at I0:21: 15 AM EST To: "Fauci, Anthony (NIH /NIA ID) [E]" -------~= Subject: NTV Broadcasting Interview Request CbH6l > Mr . Fauci, my name is Murat, I am a producer of "Week Summary" for NTV Broadcasting company . We would like to film a brief interview with you about coronavirus, and different hypotheses about its appearance . We want to solve the problem with mass disinformation about this virus, and need a professional opinion. Will it be possible to do th is at 6th , or 7 t h of February? Best regards, Seferbekov Murat NTV Broadcasting Company NIH-002170 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAI0) [E) Wed, 5 Feb 2020 14:36:13 +0000 Conrad, Patricia (NIH/NIAID) [El FW: Interview request by BBCChinese Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Tsung-Hsien Lee Date: Wednesday, February 5, 2020 8:21 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: Interview request by BBCChinese -------""="""-:-= --------- Dear Dr Anthony (b)(6) s Fauci, This is Zachary from BBCChinese. I am now writing a piece regarding the treatment of people in isolation or quarantine over coronavirus in different countries . Most of the countries told the pub lic where the people evacuated from Wuhan reside for quara ntine and some drew local's protests . They expressed concern over close vicin ity and some even went to protest in these places. Others like Taiwan, the authority decided to keep the quarantine locat ion confidential. The reason is to avoid unnecessary worr isome and let people rest wel l. I would like to have an interview with you by e-mail or Skype phone with you to give some insights or comments on this issue. If you could be quoted, the questions are as below 1. Why does the government t ell the public the quarantine location? Is it necessary? Or why not? NIH-002171 2. Many residents protested because they don't want the quarantine Center for Coronavirus in their neighborhood . Do they need to worry about it? 3. Wh at is your suggestion regarding th e location of quarantine those people from Wuhan. And wh at is essenti al for Quarantin e Center for Coronaviru s? Thank you very much for your time . Zachary Lee BBC Chinese NIH-002172 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 1 Mar 2020 01:17:02 +0000 Harper, Jill (NIH/N IAID) [E] RE:Approps TA: DOE Reimbu rsement for Coronavirus Super Computing (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . From: Harper, Jill (NIH/NIAID) [E] --------- (b)(6) Date: Saturday, February 29, 2020 9:43 AM ------==-"":":======~~ ~ ---------- To: Fauci, Anthony (NIH/NIAID) [E] (b)(6J> Cc: Haskins, Me linda {NIH/NIAID) [E] (b)( Subject: Re: Approps TA: DOE Reimbursement for Coronav irus Super Computing Tony , (b) (5) Thanks, Jill --------- From: "Harper, Jill (NIH/NIAID) [E)" Date: Friday, February 28, 2020 at 5:33:38 PM (b)(6) NIH-001 137 _______ (b) (6)> _. To: "Fauci, Anthony (NIH/NIA ID) [El" Subject: Fwd: Approps TA: DOE Reimbursement for Coronavirus Super Computing Tony, I will call you about this in a minute From: "Haskins, Melinda (NIH/NIAID) [E]" Date: Friday, February 28, 2020 at 5:24:43 PM (b)(6) -------- -:a.-r= To: "Mitchell, Michelle (NIH/OD) [El" (b)(6)> Cc: "NIAID OCGRLeg" , "LaMontagne, Karen (NIH/OD) [El" (b)(6) "Harper, Jill (NIH/NIAID) [El" (b)(6), "Johnson, Mart in -~--:---"""."""'---::====--_.:...__:__~= S. (NIH/NIAID) [E]" (b)(6) "Billet, Courtney (NIH/NIA ID) [E)" CbH6),"Shapiro, Neil (NIH/OD) [El" CbH Subject: Re: Approps TA: (b)(S) -------- (b) (5) Sent from my iPhone On Feb 28, 2020, at 5:17 PM, Mitchell, Michelle (NIH/OD) [El wrote: ---------- (b)( Hi Melinda, Would you let me know what you all think of this language? Thanks. MM (b)( > From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 5:13 PM To: Haskins, Melinda (NIH/NIA ID) [E] (b)(6) >; Mitchell, Michelle (NIH/OD) (E] (b)(6) Subject: RE: DOE Reimbu rsement for Coronavirus Super Computing ------------ -------~= Any progress on this Michelle? Here is language that I'm thinking of. For an additionalamount for "National Institute of Allergy and Infectious Di seases", to prevent, prepare for, and respond to SARS-CoV-2, a v irus sb·ain mutat ing therefrom ("coronavirus"), or other emerging or reemerging infect ious disease threa ts, domestically or internationally , $xxx,0O0,0O0, to remain avai lable NIH-001138 > until September 30, 2024: [Provided.That up to $99.500.000 of such amount s may be tran sferr ed to the D epai1rnent of Energy to provide sup po1t an d acc ess to scient ific user fac ilities , includin g equ ipm ent, ena blin g techn olog ies, and personne l ass ocia ted w ith the opernt ions of those scienti fic user fac ilities:] Laura Friedel Majority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC20510 (b)(6) From: Friedel, Laura (Appropriations) Date: Friday, February 28, 2020 3:13 PM To: Haskins, Melinda (NIH/NIA ID) [E]--------=- Cb ""' H""'>; Michelle Mitchell (b)(6) Subje ct: DOE Reimbursement for Coronavirus Super Computing Hi, Dept. of Energy is looking for $99.5 mi llion. They are concerned that NIH wil l use their super computers for coronavirus (which NIH doesn't pay for) and displace paying customers. What is the expectation that NIH will need to use DOEsuper computers? We would include addit ional funds (please make sure TF knows I would not take his funds and give to DOE), but this seems extremely high to me and I was trying to understand the need from your perspective for these super computers . Happy to jump on the phone if that is easier, but need this as fast as you can get it to me please- within the next hour or so. Language is below . Thank you ! Sec._. (a) Funds appropriated in this title may be made available to restore amounts , either directly or through reimbursement , for obligations incurred by agencies of the Department of Health and Hum an Services for the purpo ses provided herein pr ior to the date of enactment of this Act. This subsection shall not apply to obligations incurred by the Infectious Diseases Rapid Response Reserve Fund . (b) Funds appropriated in this title [may /shall] be used when [awarding /to aw ard] grants and cooperative agreements in fiscal yea r 2020 to reimburse State or local costs incurred for the purposes provided herein after January 20, 2020 , and prior to the issuance of such awards. [(c) Funds appropriated in this title shall be transferred to other federal agenc ies for costs related to medical screening for coronavirus including any costs NIH-001 139 incurred through a grant , coopera tive agreement, other transaction, or contract and, once transferred, may be used to reimbur se obligation s incurred for such purpo ses prior to enactme nt of thi s Act.] (d) U_pto $99,500,000 of the funds a ro~riated in th is title may be transferred to the Depa rtment of Energy to_provide su1;mortand access to sc ient ific user facilit ies, includin g e uipm ent, enabling technologies, and personnel associated with the o erations of those scientific user facilities. (e) If any funds have been reprogrammed or trans ferred from an appropriation , as described in the notification submitt ed by the Secretary to the Committees on Appropr ia tion s of the Hou se of Repr ese ntatives and the Senate on February 2, 2020, prior to th e dat e of enactment of this Ac t, such amounts shall be repro grammed or transferred back to that appropriation with in 45 days of the date of enactment of this Act. Laura Friedel Maj ority Clerk Committee on Appropriations Subcommittee on Labor, HHS and Education 136 Dirksen Senate Office Building Washington, DC 20510 (b)(6) NIH-001 140 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:36:17 +0000 Messonnier, Nancy (CDC/DDID/NCIRD/0D) RE: NAS Nancy: The official USGgroup will be convened by NAS. Bob Kadlec is the person with di rect knowledge of that. In addition, there is an ad hoc group informally led by Jeremy Farrar of Wellcome Trust. This group has about 15 people, all of whom are highly respected scientists, mostly evolutionary biologists who are convening by e-mail and conference calls (I have been on 2 of these calls since Jeremy invited me) to look at all of the bat, pangolin and human coronavirus sequences to try and determine the evolutionary origin. This is not my area of expertise and so I have backed off and am leaving it all to Jeremy. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives. From: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Date: Thursday, February 13, 2020 5:28 PM To: Fauci, Anthony (NIH/NIAID) [E) ------ (b)( ..-.-,= (b)(6)> Subject: RE: NAS Thanks . Is someone conven ing th em? From: Fauci, Anthony (NIH/NIAID) [E] _______ Date: Thursday, February 13, 2020 5:07 PM (b_H_6) NIH-001920 > To: Messonnier, Nancy (CDC/0010/NCIRD/OD) Subject: RE: NAS ------ (b)(6) Nancy: It is not a report. It is a letter from NASto OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/00 10/ NCIRD/OD) Date: Thursda y, February 13, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS ------~~ -------- ------- (b)(6) (b)(6) Either you or Bob Kadlec made reference to a NAS report on th e orig ins of SARS- COV2. Thanks. Nancy NIH-001921 -- From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 13 Feb 2020 22:06:37 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/OD) RE: NAS NASEM Response t o OSTP re Coronavirus_February Subject: Attachments: 6 2020.pdf Nancy: It is not a report. It is a letter from NAS to OSTP saying that it is important to bring together a group of experts to study the evolutionary origin the COVID19. I am attaching it here. I have no idea if it has been widely distributed and so please keep it internal. Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Messonnier, Nancy (CDC/0010/NCIRD/OD) Date: Thursday, February 13, 2020 1:31 PM ------~= To: Fauci, Anthony (NIH/NIAID) [E] Subject: NAS CbH > CbH6)> Either you or Bob Kadlec made reference to a NAS report on the orig ins of SARS - COV2 . Thanks. Nancy NIH-001922 -- Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 From: Date: Fauci,Anthony (NIH/NIAI0) [E) Tue, 11 Feb 2020 12:54:11 +0000 To: (b)(6) Subj ect : FW: Following Up If We can Be of Any Assistance FYI Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Kadlec, Robert (OS/ASPR/1O) Date: Tuesday, February 11, 2020 7:28 AM (b)( > To: CbH Cc: (b)(6) Elvander, Erika (OS/OGA) Joseph (OS/ASPR/EMMO) Cb)( __ ...;_-=====~:;;;---:------:----:-----:---:-(OS/ ASPR/BARD A) CbH6); Yeskey, Kevin (OS/ASPR/1O) (b)( >; Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Following Up If We can Be of Any Assistance ;........:.... _ _;_ __ ..:.!:=~"""'.'.'"-~-.--.--- --------- Lamana, Disbrow, Gary CbH6); ; --------- (b)(6) Dear Dr. Suzuki we hear d f rom Jun the new s that your Prime M iniste r gave app roval fo r t he deplo ym ent of o ur team. W e are moving expediti ous ly t o get them th ere to assist. In light of the situ at io n and t he increasing nu m bers of cases on the ship, CbH5> (b) (5) NIH-001970 Again, we are grateful and excited that we have the opportunity to work together. Kanpail Bob From: Kadlec, Robert /OS/ASPR/10) Date: Monday, February 10, 2020 8:14 PM To: (b)(6) Cc: (b)(6); Elvander, Erika (OS/OGA) Joseph (HHS/ASPR/OEM) CbH6); Lamana, _.......=====::""""'~~:-Cb)(6) (b)(6) Subject: Following Up If We can Be of Any Assistance Dear Dr. Suzuki I hope this finds you I good health and expect that you are deeply involved in the events of coronavirus in your region . I understand from various communications with the MHLW that is considering ending the quarantine early and releasing passengers from the Diamond Princess, especially those who are 80 years of age or older. Given the media reports and public perception there is pressure to do th is. However, as medical experts, you and I both know that days 3 - 8 are within the norma l incubation period and these new positives do not likely represent shipboard transmission. As such, HHS is willing to coordinate U.S. medical experts who can engage with English language media explaining and reassuring the passengers, crew, and public. Regarding support for the quarant ine, ASPRis ready to deploy a team of 3-5 people quickly, and as many 12 people to Japan to support as suggested in the previous call. If we can assist you and your team in managing the Americans currently in quarantine please let me know . If there is other support do let me know and ASPRwill work to assist. As we've talked for the past 18 months about such a scenario, this may not be the one we envisioned, but it is a perfect case as we can clearly ident ify the Americans, they are in a contained area. Our mutual efforts and planning have paid unexpected dividends. I am availab le to discuss via teleconference at your convenience. I am grateful fo r all MHLW has done to support this complicated response on top of your work supporting repatriation and domestic monitoring of your own citizens . We are grateful for Dr. Sugihara's herculean information sharing efforts and the rest of your MHLW team support during this event; it NIH-001971 validates of the importance of our ongoing liaison program and the long term benefits of our mutual commitment to each other's public health security Please remain well and I look forward to see you again soon. Best wishes and warm regards. Dr Bob Kadlec ASPR NIH-001972 From: Date: Fauci, Anthony (NIH/NIAID) [E] Mon , 10 Feb 2020 18:43:59 +0000 To: Subject: Brennan, Patrick (OS/ASPA) Hall, Bill (HHS/ASPA);Conrad, Patricia (N IH/NIAID) [E] RE: Draft of email Attachments : 2 10 20 email - with Fauciedits.docx Cc: Here is the document with my tracked changes. G Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . -----------------=-c-= From: Brennan, Patrick (OS/ASPA) Date: Monday, February 10, 2020 1:26 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Hall, Bill (HHS/ASPA) Subject: Draft of email (b)( (b)(6) > Dr. Fauci - below and in the attached is our proposed draft response , and then Cuccinelli's email text below for context. W e're waiting on a potential detail/point or two from ASPRthat may help flesh it out a bit but we'll see if we actually need it. Thank you ! << File : 2 10 20 email.docx >> Draft HHS response Fell ow t ask for ce m emb ers, Thanks for your message, Ken, and I loo k fo rw ard to ou r di scussio n tod ay. NIH-001994 (b) (5) Looking forward to discussing more later today. Ken To mv fellow task force members (b) (5) NIH-001995 (b) (5) NIH-001996 I look forward to speaking with you all again this afternoon. Patrick Bre nnan Director of Speechwrit ing Depar t ment of Health and Human Services Off ice : (b)(6) I Cell: (b)(6) NIH-001997 To: Fauci, Anthony (NIH/NIAIO) [El Sun, 9 Feb 2020 23:54:27 +0000 (b)(6) Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet From: Date: Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . (b)(6)•> From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:35 PM To: Fauci, Anthony (NIH/NIAID) [El (b)( 6) --------=-:-=:-i (b)( ; Harrison, -------- Brian (HHS/10S) Cc: Kerr, Lawrence (HHS/0S/OGA) (b)( ; Elvander, Erika (05/0GA) (b)( ·>;Zebley, Kyle (HHS/0S/OGA) (b)(6) Redfield, Robert R. (CDC/OD) (b)(6) ; Kadlec, Robert (OS/ASPR/10) (b)( (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) "':'-"--:----:-::====~ ".-:=======~= ----------------Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet Dr F, (b)(5) From: Fauci, Anthony (NIH/N IAID) [E] Date: Sunday, February 9, 2020 6:24 PM To: Grigsby, Garrett (HHS/OS/OGA)------- -------- (b) ~ > .-.. Cb .., H=6)>; Harrison, Brian (HHS/105) (b)(6j> NIH-0020 14 Cc: Kerr, Lawrence (HHS/0S/OGA) Cb)( >; Elvander, Erika (OS/OGA) (b)(6);Zebley, Kyle (HHS/0S/OGA) Cb) C >; Redfield, Robert R. ":-: (C:-:D~C:"':". /0::":: D :"':' );===='c (b~)(~ >; Kadlec, Robert (OS/ASPR/I0) (b)(6)>;Abram , Anna (b)(6) (FDA/OC) (b)(6)>; Bright, Rick (OS/ASPR/BARDA) Subjec t : RE; WHO advance team on coronavirus on way to China - Tedros tweet ~======~~ --------- -------- (b)(5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIA ID by one of its representatives. (b)(6) From: Grigsby, Garrett (HHS/0S/OGA) Date: Sunday, February 9, 2020 6:03 PM -------~~ To: Harrison, Brian (HHS/IOS) (b)(6) --:-::.::=========!~= Cc: Kerr, Lawrence (HHS/0S/OGA) CbH6J ; Elvander, Erika (OS/OGA) (b)(6); Zebley, Kyle (HHS/0S/OGA) CbH6J>; Redfield, Robert R. (C ~D :-C :-/:-:: 0:-::: D-:) :.===== (b =s ),::; (6) ~ ; Fauci, Anthony (NIH/N IAID) 7[E ::--: ]-.::=====~ (b~ )(=6)>; KadIec, Robert (OS/ASPR/10) (b)(6)>;Abram, Anna (FDA/OC) (b)(6)>;Bright, Rick (OS/ASPR ""-: / -BA _R _D_A~)--======~ (b =)-(6) ~ Subject: FW: WHO advance team on coronavirus on way to China - Tedros tweet Brian - more clarity from "the horse's mouth" on this advance trip ...see below . From: Grigsby, Garrett (HHS/OS/OGA) Date: Sunday, February 9, 2020 6:01 PM To: SCHWARTLANDER,Bernhard F. (b)(6) Cc: SIMONSON, Stewart (b)(6)> Subject: RE: WHO advance team on coronavirus on way to China - Tedros tweet --------=-cc-c= Many thanks, Bernard! I know I'll be asked, so I will pass your email up the chain ... NIH-0020 15 Take care and thanks again! (b)(6) From: SCHWARTLANDER,Bernhard F. Date: Sunday, February 9, 2020 5:59 PM To: Grigsby, Garrett (HHS/OS/OGA)-------= (b= H=6)> Cc: SIMONSON,Stewart (b)(6) Subject: Re: WHO advance team on coronavirus on way to China - Tedros tweet ---------- Hi Garrett, We have th ree people on the way to Beijing who will work with our Chinese counterparts on finalizing the TOR and composition of the joint WHO - China mission. As you are much aware, the US has given us a number of names who will be able and wi lling to jo in such a mission. We have received similar proposals from other countries and will now match the "long list" of experts with the required specific expertise. W e are hoping to have more clarity over the coming days and will obviously keep you in the loop. The overall number will be kept at a level to make sure that the team is fully operational. With my warmest wishes Bernhard Dr Bernhard Schwartlander Chef de Cabinet World Health Organization On 9 Feb 2020, at 23:24, Grigsby, Garrett (HHS/OS/OGA) wrote: --------- (b)(6)> Bernard, Hope you had a good weekend. I'm reaching out to get more clarity on the WHO experts team issue please see article below . I've heard everything from an advance group of one or two individuals to 15 people discussed in the article. I haven't heard any word about US people, and I was just with Dr Redfield late this afternoon and he was in the dark too. NIH-002016 Any additional information wil l be deeply appreciated. Thanks! From: Kerr, Lawrence (HHS/OS/OGA) (b)( > Date: Sunday, February 9, 2020 5:03 PM To: Grigsby, Garrett (HHS/OS/OGA) (b)(6); Zebley, Kyle (HHS/O5/OGA) (b)(6J>; Elvander, Erika (OS/OGA) (b)(6); Tracy Carson (b)(6) 1> Subject: WHO advance team on coronavirus on way to China - Tedros tweet -------- == ---------- February 9, 2020 / 4:01 PM/ Updated an hour ago UPDATE 1-WHO advance team on coronavirus on way to China - Tedros tweet Stephanie Nebehay By Stephanie Nebehay GENEVA,Feb 9 (Reuters)• An advance team of international experts led by the World Health Organization (WHO) has left for Beijing to help invest igate China's coronav irus epidemic, the Geneva-based agency said on Sunday. WHO director-general Tedros Adhanom Ghebreyesus, who made a trip to Beijing fo r talks with President Xi Jinping and Chinese ministers in late January, returned with an agreement on sending an international mission. But it has taken nearly two weeks to get the government 's green light on its composition, which was not announced, other than to say that WHO vetera n Dr. Bruce Aylward, a Canadian epidemiologist and emergencies expert, was heading it. "I've just been at the airport seeing off members of an advance team for the @WHO-led #2019nCoV internationa l expert mission to #China, led by Dr Bruce Aylward, veteran of past public health emergencies," Tedros said in a tweet from Geneva. Dr. Sylvie Briand, who accompanied Tedros last month and stayed behind for talks with top Chinese health officials, told Reuters last week that they were discussing a list of experts with China. "Because it is a joint mission, they need to be on board, it's not just an int ernational group going there. We have about 15 people, " said Briand, director of Global Infectious Hazard Preparedness at WHO . China raised the death toll from the coronavirus outbreak to 811 on Sunday, passing the number killed globally by the SARSepidemic, as authorities made plans for millions of people returning to work after an extended Lunar New Year break . The virus , which has spread to two dozen countries, has killed some 2% of more than 37,550 cases wor ldwide, with 99 percent of infections in China, WHO figures show. The WHO declared the outbreak a global emergency on Jan. 30, days after the Chinese central government imposed a lockdown on 60 million people in Hubei province and its capital Wuhan, epicentre of the virus that emerged in December in a seafood marke t. NIH-002017 Tedros said on Saturday that he hoped the team would include experts from the U.S. Centers for Disease Control (CDC). "It has to be meaningful on the ground," Lawrence Gostin, professor of global health law at Georgetown Law, said in an interview in Geneva this week. Gostin called for a "genuine partnership with transparent flows of information and accountability for the response", adding that there should be a strong CDC presence. "CDC has got no peer in terms of its experience and technical expertise in dealing with international outbreaks," he said. "But the other benefit is the smart diplomacy, what it could signal is that despite all of our differences in ideology, trade , politics, that when faced with a common threat to humanity, we come together as a human community to tackle it, " Gostin said. Reporting by Stephanie Nebehay; Editing by Pravin Char, Kirsten Donovan Our Standards:The Thomson Reuters Trust Prin cip les. NIH-002018 Fauci, Anthony (NIH/NIAID) [E) Fri, 7 Feb 2020 03:55:22 +0000 To: Shapiro , Neil (NIH/OD) [El;Collins, Francis (NIH/OD ) [El;Tabak, Lawrence {NIH/OD) [El;Johnson, Alfred {NIH/OD) [E];Hallett , Adrienne (NIH/OD) [El Cc: Shaya, Cecile (NIH/OD) [El Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold From: Date: (b) (5) From: Shapiro, Neil {NIH/OD) [El (b)(6) Sen t : Thursday, February 6, 2020 8:08 PM To: Collins, Francis (NIH/OD) [El (b)( >; Tabak, Lawrence (NIH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6) >; Hallett, Adrienne "":"----:----:-:-:-::-====::!.....:.--~~ (NIH/OD) [El (b)( ; Fauci, Anthony (NIH/NIA ID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6) Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold -----~ = (b) (5) Neil From: Collins, Francis (NIH/OD) [El (b)(6) Se nt: Thursday, February 6, 2020 4:59 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6); Tabak, Lawrence {N IH/OD) [El (b)(6)>; Johnson, Alfred (NIH/OD) [El (b)(6)>; Hallett, Adrienne "":"----:-:-:-:-:-:-::.:====:::::..;,-~= (NIH/OD) [El (b)(6)>; Fauci, Anthony {NIH/NIAID) [El (b)(6) Cc: Shaya, Cecile (NIH/OD) [El (b)(6)> Subject: RE: Coronavirus - HHS Supplemental Table - Close Hold (b)(S) FC ------- (b)(6)> From: Shapiro, Neil {NIH/OD) [E] Date: Thursday, February 6, 2020 3:22 PM To: Collins, Francis {NIH/OD) [El (b)(6); Tabak, Lawrence {NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E) (b)(6)>; Hallett, Adrienne "":"----:----:-:-:-::-====::t....:--___:~ (N IH/OD) [E) (b)( Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Shaya,Ce ... c:-:ile- (:-:N~IH~/:--:: 0-::07'" ) [:-:: E-::-. l ====--..;_ (b ""' )-:--=(6) ------- ------= Subject: FW: Coronavirus - HHS Supplemental Table - Close Hold Impo rt ance: High NIH-002087 ASFRprovided the pdf attachment and the explanation below. They emphasized on the phone too that this is very close hold . Cb) (5 i (b) (5) Neil From: Cabezas, Miriam (HHS/ASFR) Se nt : Thursday, February 6, 2020 2:32 PM To: Kelly, Alison (CDC/OCOO/OFR/OA) ----~~ (b)(6)>;Berger, Sherri (CDC/OCOO/O0) CbH ; Shapiro, Neil (NIH/OD) [E) CbH6)>; Shaya, Cecile (NIH/OD) [E] 7 Cb~>; Peti llo, Jay (OS/ASP':"' R/ M -:-F ::-:H-:-: C~) -====~ CbH6J>; Dubay, Johanna ----------- =====~ (OS/ASPR/M FHC) Cc: Goyle, Suraj (OS/ASFR) White, RaeShawn (OS/ASFR) (b)(6) (b)(6)>;Falisi, Angela (OS/ASFR) CbH6J>; Cormier, Justin (HHS/ASFR) (b) (6)>; (b) ( > Subject: Coronavirus - HHS Supplemental Table - Close Hold Information in this email is close hold. Good afternoon Attached you w ill find CDC, ASPR, and NIH specific totals that were provided to 0MB last night. We want to make sure you have awareness of the activities that are identified across these three agencies. Let us know if you have any questions . This information should not be shared broadly. Miriam NIH-002088 From: Fauci, Anthony (NIH/NIAIO) [El Date: Fri, 7 Feb 2020 03:38:07 +0000 To: Marston, Hilary (NIH/NIAID) [E] Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Please t ake care of this on my behalf. Thanks. From: Marston , Hilary (NIH/NIAID) [E] (b)(6) Se nt: Thursday, February 6, 2020 3:11 PM ------~~ To: Harris, Kara (NIH/NIAID) [E] (b)( ; Handley, Gray (NIH/NIAID) [E] < (b)(6J>; Lerner, Andrea {NIH/N IAID) [El (b)(6J> ; Eisinger, Robert {NIH/NIAID) [E] (b)(6)>; Harper, Jill (NIH/NIA ID) [El CbH >; McGowan, John J. {NIH/NIAID) [E] (b)( ; Billet, Courtney {NIH/NIAID) [E] CbH >; Auchincloss, Hugh {NIH/N IAID) (E] CbH6J> Cc: NIAID OCGRCorrespondence ; Gilles, Sharon (NIH/NIAID) [E) (b)(6) Fauci, Anth ony (NIH/N IAID) [E) (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)( > Subject: RE:** Time-Sensitive Clearance** DUE BY 3:30 TODAY- Coronavirus- Minister Ma of China Response Letter - 00430215 ------- (b)(5) From: Harris, Kara (NIH/NIAID) [El CbH6)> Sen t : Thursday, February 6, 2020 3:00 PM To: Handley, Gray (NIH/NIAID) [E]---------=(b""" )(=6) Marston, Hilary (NIH/NIAID) [El (b)(6)>; Lerner, Andrea (NIH/NIAID) [E] (b)(6); Eisinger, Robert (NIH/NIAID) [E] (b)(6) Harper, Jill (NIH/NIA ID) [El (b)( McGowan, John J. {NIH/NIAID) [E] < (b)(6) >; Billet, Courtney (NIH/NIAID) [El (bH >; Auchincloss, Hugh (NIH/N IAID) [E] (b)(6)> Cc: NIAID OCGRCorresponde nce ; Gilles, Sharon (NIH/NIAID) [E] (b)(6) --------- NIH-002093 Subject: FW: ** Time-Sensiti ve Clearance** DUE BY3:30 TODAY- Coronavirus - Minister Ma of China Response Letter - 00430215 Importance: High AllPlease see the note below from ExecSec. Please provide any comments to NIAID OCGR Correspondence by 3:30 p.m. Please note - ExecSec is looking for show-stoppingcommentsonly. Thank you, Kara ------------------=-c-=, From: Malliou , Ekaterini (OS/10S) (b)(6)> Date: Thursday, February 6, 2020 2:25 PM To: Stannard, Paula (HHS/IOS) (b)(6); Hoffmann, Lauren (CDC/OD/OCS) (b)(6)>; Clark, Cynthia K. (CDC/OD/OCS) (b)(6); Stimson, Brian (HHS/OGC) (b)(6) Chang, William {HHS/OGC) (b)(6)>; Barry, Daniel J --~-.-:::====:!.-(HHS/OGC)"'~~-.-:::==== ..;;.:. ~ >.:..;_sh_u.:.,y;,.,B~ryan (OS/ASPR/10) (b=)(=6)::.. (b)(6); Bird, Catherine (05/0GC) (b)(6) OSOGC-10; ASPRExec Sec (OS/ASPR) Cc: Steele, Danielle (HHS/IOS) (b)(6); Agnew, Ann (HHS/10S) (b)(6) >; Hawk ~i-ns-,-:Ja -m - ar- (:-:H:-:H-:-: S-: /0".:"":"'. S):-.:==:;.....::;._...:,__...:...~ (b:.,. ) .,-=, (6); Horska, Katerina (HHS/IOS) Zebley, Kyle (HHS/0S/OGA) (b)(6)>; Varnado, Martina (FDA/OC) (b)(6)>; Allen-Gifford, Patrice (NIH/OD) [E] -------- Subject: Clearance Due 6pm (2/6): **Time -Sensitive** (b)(6); (b)(6) Coronavirus - Min iste r Ma of China Response Lette r - 004302 15 Please find attached for your clearance a response to Minister Ma's letter to the Secretary,and a recent conversationwith him. (b) (5) Please note that the Secretary has already reviewed and edited the attached response We appreciateyour expedited review and clearance by 6pm today, 2/6. Thank you, Kat **************************************** Ekaterini (Kat) Malliou , DrPH, MPH Senior Policy Coordinator [mmediate Office of the Secretary, U.S. Department of Health and Human Serv ices 200 Independence Ave SW, Suite 619H, Washington, DC 20201, USA Tel: (b)(6) Cell : (b)( , Email: (b)(6) NIH-002094 From: Date: (b)(6) Thu, 6 Feb 2020 18:56:07 -0500 Conrad, Patricia (NIH/NIAID) [E) Billet, Courtney (NIH/NIAID) [El To: Cc: Subject: Re: FROM CAITLIN OAKLEY-Atlantic reporter responded Please schedule call for tomorrow. On Feb 6, 2020, at 4:17 PM, Conrad, Patricia (NIH/N IAID ) [E] ---------- (b)(6) wrote: See below -the reporter responded to Caitlyn - not Courtney- he can speak today or tomo rrow. Do you want to call tonight or have me schedule for tomorrow? Tomorrow is quite full but can make it happen ...let me know Yes, happy to talk today or tomorrow. I'm at (b) (6) If D r. Fauc i is avai lable, that would be great. Be st, Peter Nicholas Patr icia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Inf ect ious Diseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The informationin this e-mail and any of its attachmentsis confidential and may contain sensitiveinformation. It NIH-002101 shou ld not be used by anyone who is not the origina l intended recipient. If you have rece ived this e-ma il in error please inform the sender and delete it from your mailbox or any other storage devioes. National Institute of Allergy and Infectious Diseases (NIAID ) shall not accept liability for any statement made that are sender's own and not express ly made on behalf of the NIAID by one of its representatives . ---------- From: Oakley, Caitlin B. (OS/ASPA) ~ (b)(6)> _______ ------ ~= Date: Thursday, February 6, 2020 4:12 PM To: Billet, Courtney (NIH/N IAID) [El [El (b) (6) Subject: FW: follow up re: Coronavirus story (b)(_, >; Conrad, Patricia (NIH/NIAID) Caitlin B. Oakley Deputy Assis tant Secretary, Nat ional Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)(6)) From: Peter Nicholas Date: Thursday, February 6, 2020 3:00 PM To: Oakley, Caitlin B. {OS/ASPA) Subject: Re: follow up re: Coronavirus story ------------------=---= (bH > Hi, Yes, happy to talk today or tomorrow. I'm at (b)(6). If Dr. Fauci is available, that would be great. Best, Peter On Thu, Feb 6, 2020 at 11:09 AM Oakley, Caitlin B. (OS/ASPA) (b)(6) wrote: ----------Fo11owing up on this .... does today work? And I know Dr. Fauci's office is trying to get in contact as well. He's a member of the taskforce. Can we make this happen? Caitlin B. Oakley Deputy Assistant Secretary, National Spokesperson Office of the Assistant Secretary for Public Affairs U.S. Department of Health and Human Services (b)(6) NIH-002102 From: Oakley, Caitlin B. (OS/ASPA) Date: Wednesday , February 5, 2020 3:55 PM To: pnicho las@theat lant ic.com Cc: Hall, Bill (HHS/ASPA)_____ Cb _ )_(6) _> Subject: follow up re: Coronavirus story Pete r- Thanks for the chat yesterday. Have a few folks that I'd like to get you on the phone with about your p iece. Wou ld you have time to chat with Bi ll Ha ll and I later today ? And when is your deadline for the piece? Talk soon, Caitlin B. Oakley Deputy Assistant Secretary, Natio nal Spokesper son Office of the Assistant Secretary for Public Affairs U.S. Departmentof Health and Human Services (b)( NIH-002103 Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 202015:21:22 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE: Redfield/Fauci nCoV op-ed Att achment s: Coronavirus OpEd - Redfield and Fauci - 02-06-2020.docx From: Date: Here it is. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It shou ld not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Wednesday, February 5, 2020 3:43 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIA ID) [El ; Folkers, Greg (NIH/NIAID) [E) (b)(6J>; Routh, Jennifer (NIH/NIAID) [E) (b)( ; Stover, Kathy (NIH/NI A ID) [E] (b)(6)> Subject: FW: Redfield/Fauci nCoV op-ed ------ ::;..,..-,= ~=======-~= --------- Here is the op-ed as cleared by WH . Any issues with this? (b) (5) From: Brennan, Patrick (OS/ASPA) Date: Wednesday, February 5, 2020 3:39 PM To: Routh,Jennifer (NIH/NIAID) [E] (b)(6) -------~~ (b)( 6) --------- (b)(6); Lepore, Loretta (CDC/0D/OCS) Cc: Fine, Amanda (NIH/OD) [E] (b)(6) Galatas, Kate (CDC/0D/OADC) (b)(6J>; Bonds, M ichelle E. (CDC/0D/OADC) (b)(6)>; Conrad, Patricia (NIH/NIA ID) ':": [E::)====..,.._ (b)(6J>; Billet, Courtney (NIH/NIAID) [El (b)(6); McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell, Amanda (CDC/0D/OCS) (b)(6); NIH-002 108 Stecker, Judy (OS/IOS) Pratt , Michael (OS/ASPA) CbH6J;Murphy, Ryan (OS/ ASPA) CbH6J (b)(6)0akley, Caitlin 8. (OS/ASPA) (b)(6J>; Hall, Bill (HHS/ASPA) (b)(6)> ; Myles, Renate (NIH/OD) [E] (b)( 6); Burk low, John (NIH/OD) [E] (b)(6J>; Stover, Kathy (NIH/NIAID) ========,~';5""=-~[E~l =====~ (b~)(=6) Subject: RE: Redfield/Fauci nCoV op-ed Attached is a tracked changes version and a clean version of what cleared the WH - they had a few sentences they would like to be added (wh ich, in the tracekd changes version, I have added comments to explain who suggested it and in some cases why), but almost all of these edits are non-substantive. Assuming CDC and NIAID are good with these (feel free to mod ify the addit ions as needed), you all are good to pitch this as you wish (b) (5) From: Rout h, Jenn ifer (NIH/NIAID) [E] Date: Sunday, February 2, 2020 6:11 PM To: Lepore, Loretta (CDC/OD/OCS) ---~~ Cc: Fine, Amanda (NIH/OD) [El CbH >; Galatas , Kate (CDC/OD/OADC) (b)(6)>; Brennan, Patr ick (OS/ASPA) (b)( >; Bonds, Michelle E. (CDC/OD/OADC) (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b)(6)>; Billet, Courtney (NIH/NIAID) [El (b)(6)>; McGowan, Robert (Kyle) (CDC/0D/OCS) CbH >; Campbell, Amanda (CDC/0D/OCS) CbH6J>;Stecker, Judy (OS/IOS) (b)(6)>; Murphy, Ryan (OS/ASPA) (b)(6)>; Pratt, Michae l (OS/ASPA) (b)(6)>; Oakley, Caitlin B. (OS/ASPA) CbH6J>; Hall, Bill (HHS/ ASPA) (b)(6); Myles, Renate (NIH/OD) [E] (b)(6) ; Burklow, John (NIH/OD) [El (b)(6J; Stover, Kathy (NIH/NIAID) [E] (b)(6) Subject: RE: Redfield/Fauci nCoV op-ed ------ :::======~=---c-c= ' --~--~====:::!,_.:,___~~ All - attached is a track changes draft and a clean version with input from NIAID and Dr. Fauci. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communi cations and Government Rela tions National Institute of Allergy and Infectio us Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct: Cb)( Disc laim er: The information in this e-mail and any of its attachments is confidential and may conta in sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived th is e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute or Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf or the NIAID by one of its representatives. From: Lepore, Loretta (CDC/OD/OCS) ____ Date: Sunday, February 2, 2020 2:39 PM Cb _>_C6) _ NIH-002109 To: Fine, Amanda (NIH/OD) [E]; Galatas, Kate (CDC/00/0ADC ); Brennan, Patrick (OS/ASPA); Bonds, Michelle E. (CDC/0D/OADC}; Conrad, Patricia (NIH/NIAID} [El; Billet, Cou rtney (NIH/NIAID} [El Cc: McGowan, Robert (Kyle) (CDC/OD/OCS); Campbell, Amanda (CDC/0D/OCS}; Stecker, Judy (OS/10S}; Murphy, Ryan (OS/ASPA}; Pratt, Michael (OS/ASPA); Oakley, Caitlin B. (OS/ASPA); Hall, Bill (HHS/ASPA}; Myles, Renate (NIH/OD} [E] Subject: RE: Redfield/Fauci nCoV op-ed Good afternoon all, I am forwarding the op-ed drafted by CDC and reviewed by Dr. Redfie ld for review by Dr. Fauci and ou r co lleagues at NIH. Please reach out with any quest ions. Best, Loretta ------------,.= From: Fine, Amanda (NIH/OD) [El (b)(6) Se nt: Friday, January 31, 2020 6:36 PM To: Galatas, Kate (CDC/0D/OADC} (b)(6)>; Brennan, Patrick (OS/ASPA} (b)(6)>; Bonds, Michelle E. (CDC/0D/OADC} (b)(6)>; Conrad, Patricia ":": (N":".' l'."':' H/":':' N"."'." IA ~l-:D}:-:[~E]:-::::::===-,:_-~ (b ;a-,~=c6); Billet, Courtney (NIH/NIAID} [E] (b)(6)>; Lepore, Loretta (CDC/00/0CS} (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/00/0CS) (b)(6) • Campbell, Amanda (CDC/0D/OCS) (b)(6)>; Stecker, Judy (OS/IOS}.,..;..::::=====:=;. (b""' )(=6); Murphy, Ryan (OS/ASPA} (b)(6); Pratt, Michael (OS/ASPA} 7( 0:-:S :-: /A -:-S :-:P:-:A-:} -.======;...._--= (b"'" ) """' (6)>; Hall, BiII ( HHS/ASPA} (NIH/OD) [E] ______ _____ (b)(6); Oakley, Caitl in 8. _,, Myles, Renate (b) (6)>; Cb _>_ C6) Subject: RE: Redfie ld/Fauci nCoV op-ed + Renate Myles for awareness ------ From: Galatas, Kate (CDC/OD/OADC} (b)(6) Date: Friday, January 31, 2020 6:34 PM To: Brennan, Patrick (OS/ASPA} (b)(6) >; Bonds, Michelle E. (CDC/0D/OADC) (b)(6); Fine, Amanda ":' (~ N :-:IH:-:/O~ D:-: } [::E-:] -:=====...:....__, (b a-,~~<6)>;Conrad, Patricia (NIH/N IAID) [E] ------~~ =====:=;..--=- 1 (b.,.:, )( = 6)>; Billet, Courtney (NIH/NIA ID) [E] ------- (b)(6)1 >; Lepore, Loretta (CDC/00/0CS} (b)(6) Cc: McGowan, Robert (Kyle) (CDC/0D/OCS) (b)(6)>; Campbell , Amanda (CDC/OD/OCS) ,..:..!::====::::::_:_~ (b)(6)>; Stecker, Judy (OS/10S} (b)(6); M urphy, Ryan (OS/ASPA} (b)(6)>; Pratt, Michael (OS/ ASPA} (b)(6) Oakley, Caitl in B. (05/ASPA} (b)(6); Hall, Bill (HHS/ASPA} (b)(6) Subject: Re: Redfield/Fauc i nCoV op-ed Hi, Patrick We've put t his in motion - once it's cleared thru CDC, we wi ll send back to this group so NIH comms can move thru with thei r editing/revisions. NIH-002 110 let me know if that sounds OK. We will likely not have a cleared version out of CDCuntil late Saturday at the earliest. Take care, Kate Get Out look for iOS From: Brennan, Patrick (OS/ASPA) (b)(6) Date: Friday, January 31, 2020 5:31:46 PM To: Bonds, Michelle E. (CDC/0D/OADC)____ (b ~ )- (6) = > ; Fine,Amanda (NIH/OD) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El < (b)(6)>; Billet , Courtney (NIH/NIAID) [El (b)( >; Lepore, Loretta (CDC/O0/OCS) (b)(6)> Cc: McGowan, Robert (Kyle) (CDC/OD/OCS) (b)(6) ; Campbell, Amanda (CDC/OD/OCS) (b)(6)>; Stecker, Judy (OS/1OS) (b)(6); Mu rphy, Ryan (OS/ASPA) (b)(6); Pratt, Michael (O5/ASPA) (b)(6); Oakley, Caitlin B. ":"::":--:-'.:-:-::--:-:-::=====::....-~~ (OS/ASPA) (b)(6)>; Hall, Bill (HHS/ASPA) (b)(6)>; Galatas, Kate (CDC/OD/OADC) (b)( > Subject: Redfield/Fauci nCoV op-ed CDC and NIH folks, Per some discussion after the presser, we'd like Dr. Redfield and Dr. Fauci to pen an op-ed regarding the reasons/thinking behind the policy announced today. I assume the right building blocks for it would be the remarks they made today- which I believe you all should have the copy/notes for? I have the Secretary's, which we'll be send ing around/post ing shortly and I'll make sure to re-up it here so you all have it. It would be great to have a draft of this cleared to get to the WH over the weekend. (I anticipate faster than-average clearance from them!) Please let me know how I can help wi th t his. Best, Patrick Patrick Brennan Director of Speechwriting Depa rtmen t of Health and Hum an Services Office: (b) (6) I Cell (b) ( Predecisional/deliberative communication NIH-002111 To: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:54:16 +0000 Billet, Courtney (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Cc: Subject: Att achment s: Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E] RE:ASF: rAzar/Pompeo op-ed 2 5 20 pompeo azar op-ed State - with Fauci tracked edits..docx From: Date: Here are my tr acke d ed its. Tha nks. Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [El (b)(6)> Sen t : Thursday, February 6, 2020 7:31 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH >; Folkers, Greg (NIH/NIA ID) [E] _______ Cb _>_ C6);Marston, Hilary (NIH/NIAID) [E] (b)(6) ------ == Cc: Conrad, Patricia (NIH/NIA ID) [E] (b)( > Subject: ASF: rAzar/Pompeo op-ed CbH ; Routh, Jennifer (NIH/NIAID) [E] Sending to all of you simultaneously, in the interest of time. Our comments are due back at noon . (b)(6)> From: " Brennan, Patrick (O5/ASPA)" Dat e: Thursday, February 6, 2020 at 1:23:26 AM To: "Routh, Jennifer (NIH/NIAID) [E]" ------= (b...., H=6)>, "Bonds, Michelle E. (CDC/OO/OADC)" (b)(6), "Galatas, Kate (CDC/OD/OADC)" (b)(6)>, "Fine, Amanda (NIH/OD) [El " :::::======~~(b)(6)>, "Conrad, Patricia (NIH/NIAID) (E]" (b)(6)>, "Kane, EIieen (OS/ASPR/OE A)" (b)(6J>, " Michael, Gretchen (O5/ASPR/OEA)" ,;___;__ _;____,:_::::==:::;(b ~~~<6) ;-,-::,,:-: Bi:lle ::---:t----:= , Courtney (NIH/NIA I D) [E]" (b)(6)>, "Lepo re, --------- Loretta (CDC/OD/OCS)" (b)(6), "McGowan, Robert (Kyle) (CDC/OD/OCS)" " Campbell, Amanda (CDC/OD/OCS)" (b)(6J>, "Zebley, Kyle (HHS/O5/OGA)" NIH-002 112 (b)(6), (b)(6)> , "Chang, Will iam (HHS/OGC)" (b)(6), "Keveney, Sean ---:-:-'.".""."::-:-:"-:-:'":-:"-:--:-:'.:.==:::::.---..:.:..-_.,,-:-:= (HHS/OGC)" (b)( >, "Grigsby, Garrett (HHS/OS/OGA)" (b)(6) Cc: "Billet, Courtney (NIH/NIAID ) [E]" (b)( >, "ASPA-Deputies" Subject: For review by noon Thurs: revised Azar/Pompeo op-ed ---------- Hi all , At t ached is a largely new draft of the Azar/Pompeo op-ed tha t ------------------------------- (b) (5) I've made a couple additions and ed its to their new version , which I've tracked/flagged. NIAID, CDC, and OGC, please let me know if thi s looks OK by noon tomorrow . Thank you! Best, Pat rick NIH-002 113 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Thu, 6 Feb 2020 14:24:54 +0000 To: Billet, Courtney (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Routh, Jennifer (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E] Subject: RE:ASF: for review, Azar coronavirus presser remarks Attachments: Secretary's remarks with minor Fauci edits.docx Here are my edits for Azar' s press comments Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and n ot expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] (b)(6) Date: Thursday, February 6, 2020 7:29 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Cc: Folkers, Greg (NIH/NIAID) [El (b)(6)>; Conrad, Patricia (NIH/NIAID) [El (b)(6); Routh, Jennifer (NIH/NIAID) [El CbH6>1; Marston, Hilary -:--.-----:-:-:-:-:::====~-___:-~= (NIH/NIAID) [El (b)(6); Stover, Kathy (NIH/NIAID) [El (b)(6)> Subject: ASF: for review , Azar coronavirus presser remarks --------=-<~ Pis see Secretary's remarks for press conf and let us know if anything glaring needs to be fixed. They also would like talking points from us, covering what you would say. These are really just a placeholder. We could resubmit what we sent last time. Is there anything new you would anticipate saying? From: "Brennan, Patrick (05/ASPA)" Date: Wednesday, February 5, 2020 at 11:25 :33 PM To: "Routh, Jennifer (NIH/NIAID) [El" 77 (b)( >, "Galatas, Kate (CD. ":C'."-:/O::-D ::-/:-: O:-: A-:: D-:: C)' :-:: ' --------- (b)(6)>, "Bonds , Michelle E. (CDC/00/0ADC)" ==.,.......... (b)(6), =====::::!.--=-=-~ (b)(6)>, "Conra d, Patricia (NIH/NIAID) [El" -------NIH-002116 "Fine, Amanda (NIH/OD) [E]" (b)(6J>, "Kane, EIieen (OS/ASPR/OEA)" CbH6J>," M ichael, Gret chen (OS/ASPR/OEA)" ,;._..;___..;______;_::::==' (b :;;)::;, (6) =a" >-,-::,,:"'. Bi~lle-t~, Courtney (NIH/NIA I D) [El" (b)(6), "Steele, (b)(6)>, Danielle (HHS/105)" (b)(6)>, "Arbes, Sarah (HHS/ASL)" " Moughalian, Jen (HHS/ASFR)" (b)(6) , "Shuy, Caitrin (HHS/ASFR)" (b)(6), "Caliguiri , laura (FDA/OC)" (b)(6)>, "Janik, Heather (FDA/OC)" (b)(6)>, "Lepore, Loretta (CDC/0D/OCS)" (b)(6)1, " McGowan, Robert (Kyle) (CDC/0D/OCS)" (b)(6)>, "Campbell, Amanda (CDC/0D/OCS)" CbH, "Zebley, Kyle (HHS/OS/OGA)" (b)(6), "Chang, William (HHS/OGC)" (b)(6)>, "Keveney, Sean (HHS/OGC)" (b)(6)>, "Pence, Laura (HHS/ASL)" (b)(6)"Grigsby, Garrett (HHS/OS/OGA)" (b)(6)> Cc: "Billet, Courtney (NIH/NIAID) [E]" (b)( >, "Stover , Kathy (NIH/NIAID) [E]" (b)(6)>, "ASPA-Deputies" Subject: For review by 11 AM Thurs: Sec. Azar coronavirus presser remarks ----:~~====~:___-~..;,· -------Hi all, Attached are draft remarks for the Secretary to deliver tomorrow evening at the scheduled press conference on coronavirus- after which the plan is for Dr. Redfie ld and then Dr. Fauci, and then whoever from State and OHS (I think?) to speak. Can CDC, NIAID, OGC, FDA, and ASPR let me know if thi s looks OK by 11 AM tomorrow? And once CDC and NIAID have their draft TPs, it would be great to see those as well. Thank you! - Patrick NIH-002117 From: Date: Fauci, Anthony (NIH/NIAID) [El Thu, 6 Feb 2020 03:59:18 +0000 To: Grigsby, Garrett (HHS/0S/OGA);Lane, Cliff (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [E];Zebley, Kyle (HHS/0S/OGA);Kerr, Lawrence (HHS/0S/OGA);Burr, Mara (HHS/0S/OGA);Levine, Maya (OS/OGA);Mciff, Colin (HHS/0S/OGA);Arboleda, Nelson (HHS/0S/OGA);Alexander, Thomas (OS/OGA) Subject: RE:Coronavirus collaborating center Yes. Thanks you. -----Original Message----From: Grigsby , Garrett (HHS/OS/OGA) Date: Wednesday , February 5, 2020 8:42 At'vl To: Fauci , Anthony (NIH/NIAJD) [E] --------- -------(b)(6) ------, (b) (6) > ,,.,..,-= >; Lane, Cliff (NTH/NJACD ) [E] (b)( ------- Cc: Marston , Hilary (NTH/NTATD)[E] (b)(6) ; Zebley, Kyle (HHS/OS/OGA) (b) (6) ; Kerr, Lawrence (J-lHS/OS/OGA) .....,.,._.,. (b) ( ; Burr , Mara (HHS/OS/OGA) (b) (6) > ; Levine, Maya (OS/OGA) ..... ___ (b)(6); Mciff , Colin (HHS/OS/OGA) (b) (6) Arboleda , Nelson (HHS/OS/OGA) (b) ( ; Alexander, Thomas (OS/OGA) (b) (6)> Subject: FW: Coronavirus collaborat ing center lmportance: High ....................... ----, ---,--------- DrsF & L, Confinning that you want me to reply in the affirmative asap ...? __________ -----Original Message----_, (b)(6) > f rom: Lamourelle , Gabrielle (HHS/OS/OGA) Date: Wednesday , Febrnary 5, 2020 6:50 AM ~= To: Grigsby , Garrett (HHS/OS/OGA) ------~ (b) (6); Mciff, Colin (HHS/OS/OGA) (b) (6) ; Kerr , Lawrence (HHS/OS/OGA ) (b) ( >; Burr, Mara (HHS/OS/OGA) (b) (6) ; Elvander, Erika (OS/OGA) (b) ( Cc: Tracy Carson (b)( ; Smith , Steven T (Geneva) (b) ( art, Jessica L. (b ood, Rachel (HHS/OS/OGA) Cb)C ; Levine, Maya (OS/OGA) (HHS/OS/OGA) (b)( ·; Fernandez, Jose (OS/OGA) Subject: FW : Coronavirus collaborat ing center lmportance: High ------- --------- Dear Garrett and all, I have received the hard copy of the attached letter from Matias Tuler (WHO Collaborating Centers team) with the request that we review and provide a reply as quickly as possible. The letter, as usual form, says they will go forward in 8 weeks if they hear no objection from us. (b) (5) If you have any questions, let me know. Thank you, Gabrielle -----Original Message----From: TULER, Matias Cb)(6) Date: Wednesday , February 5, 2020 9:35 AM ---- --,;-;= NIH-002 145 (b)( To: Lamourelle, Gabrielle (HHS /0S /OGA) Cc: OGA Multilateral Subject: RE: Coronavirus collaborating center Dear Gabrielle , Many thanks for the email. 1 sent you an email with the letter just after we talked. 1do not know if you received it. ram attaching the letter to this email again, just in case. Thank you very much in advance. Best regards , Matias Matia s Tuler Programme Manager WHO Collaborating Centres, and WHO Expert Advisory Panels and Committees World Health Organization Geneva , Switzerland Office: (b) (6) Web: http://www .who .int/collabora tingcentre s/infonnat ion/en/ http://www .who.i nt/about/collabo rations/expert panels/en/ Follow WHOon Facebook, Twitter, YouTube, Instagram -----Original Message- ---From: Lamourelle , Gabrielle (HHS/0S /OGA) Date: Wednesday , February 5, 2020 9: 17 To: T ULER, Matias (b)(6) Cc: OGA Multilateral Subje ct: Coronaviru s collaborating center ------------ (b)(6) > Dear Matia s, Thank you for sharing the hard copy of the Corona virus col laborating center letter. Please send me an electronic copy as well and J will send back immediately to our office for a rapid reply. With best wishes, Gabrielle Lamourelle Deputy Director, Multilateral Relations HHS Office of Global Affairs Sent from my iPhone NIH-002 146 From: Date: To: Cc: Subjec t: Fauci, Anthony (NIH/NIAID) [E) Thu, 6 Feb 2020 02:55:19 +0000 Kerr, Lawrence (HHS/0S/OGA) Grigsby, Garrett (HHS/0S/OGA) RE:Spoke with Soumya re: evolut ionary origin of nCoV I do not see any prob lem with your doing this. Go for it. Best, Tony From: Kerr, Lawrence (HHS/0S/OGA) Date: Wednesday, February 5, 2020 7:18 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)( > Cc: Grigsby, Garrett (HHS/OS/OGA)'"=======~ (b ""' )~(6)> Subject: Spoke with Soumya re: evolut ionary origin of nCoV ---------- Dr . Fauci, (b) (5) I welcome you r advice please . Much thanks, Larry NIH-002 149 From: Date: (b)(6) To: Subject: Wed, 11 Mar 2020 19:30 :25 -0400 John M Jessup Re: You are great - a thought Kim: Thanks for the note. That is exactly what the cdc is sta1i ing to do. Best, Tony On Mar 11, 2020 , at 7:22 PM, John M Jessup --------- (b)(6) wrote: Tony, (b)(6) from NCI We have seen each othe r over the decades. I am the who decreid the lack of info r mation about Eboal since it was limited to fruit bats as a reservoir. An idea about testing . Maryland sti ll has testing limited to subjects with symptoms who have contact with people from affec t ed areas or who real ly ill with a respiratory infection Why not forget the contacts and t est those with flu-like symptoms without the need for contacts but instead test for fl u and if that is negative move on to covid -19. That would still be a tr emendous demand so ... go to a formal two -ti er t est wh er e PCR is done with approved PCR primers and if that is positive then the confirmation is with a FDA t est for covid - 19. There are a lot of manufacturers of PCR primers, most clinical labs have PCR machines so that screening t ests ought to be supported wit hou t a lengthy FDA clearance if it w innows the number of patients who need a formal test. You are terrific . Keep it up with common sense as opposed to whatever the t op of the administration suggests. I bet that the primer manufacturers would be supportive . Kim J. M ilburn Jessup, MD, FACS Research Scientist Division of Research Washington DCVAMC 50 Irving Street NW Washington, DC 20422 (b)(6) or_______ °" )'""' (b (=6) Affil iate Professor - Systems Biology NIH-000677 College of Science George Mason University (b)(6) ----- (b)(6) Diagnostics Evaluation Branch, CDP, DCTD, NCI, NIH NIH-000678 (b)(6) From: Wed, 5 Feb 2020 08:56:13 -0500 Date: Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E];Lane, Cliff (NIH/NIAID) [E];Morens, David (NIH/NIAID) [E] To: Subject: Re:favor (b)(6).(b)(4) On Feb 5, 2020, at 8:29 AM, Baden, Lindsey, M .D. wrote: Ton'l,'------------------------- (b ,..., )"(6) " . .. (b"') ..,.., ~l Lindsey From: "Fauci, Anthony (NIH/N IAID) [E]" -------- (b)(6) Date: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." --------~= Cc: "Marston, Hilary (NIH/ NIAID) [E]" CbH6) "Conrad, Patricia (NIH/ NIAID) [E]" Cb)( , " Lerner, Andrea (NIH/ NIAID) [E]" ,;.__:_ _ __;_...:......:....:::= (b ~)~C6) ;;-,--:,:-:,L-a n-e-, -= c::-: lif::f -:-:( N-:-:1:--:-'. H/ N IAID) [El" (b)(6)>, "Mo rens, David (NIH/N IAID) [El" Subject: RE:favor CbH6)> Lindse : (b)(6).(b)(4) Best regard s, To ny Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 NIH-002173 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301) 496-4409 E-mai l: (b) (6) The information in this e-mai l and any of its attachments is confidential and may contain sensit ive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage dev ices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not express ly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E)"======= Cc: Marston, Hilary (NIH/NIAID) [E] (NIH/NIAID) [E] (b)(6) Subject: Re: favor ---------=-c-c= Tony (and Hilary), Much appreciated. Thank you, Lindsey ------- (b=)( ::-! 6)~ (b)(6); Conrad, Patricia (b) (6), (b) (4) . --------- From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" J (NIH/N IAID) [E]" (b)(6) (b)(6) Cb)C6J, "Conrad, Patricia Subject: RE: favor Lindsa : (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health NIH-002174 Bethesda , MD 20892-2520 Phone: Cb ) (6) FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID ) [E) Subje ct: favor --------::-:-c-= -------- Tonv. (b)(6) (b) (6). (b) (4) Thank you for considering, Lindsey This email message is a private communication. The information transmitted, including attachments, is intended on ly for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of , or ta king of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential , privileged, and/or proprietary mater ial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The infonnation transmitted , includin g attachments, is intend ed only for the person or entity to which it is addre ssed and may contain confidential, privileged , and/or proprietary materia l. Any review , duplication , retransmis sion, distr ibution , or other use of, or taking of any action in relianc e upon, this information by person s or entiti es other than the intended recipient is unauthorized by the sender and is prohibited. If you have NIH-002 175 received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002176 From: Date: (b)(6) Wed, 5 Feb 2020 08:41:40 -0500 To: Subject: Baden, Lindsey, M.D . Re: favor Thanks , Lindsey. I am always happy to help in any way I can On Feb 5, 2020, at 8:32 AM, Baden , Lindsey, M .D. wrote: Tony, On a different note, as the spread of the nCoV-2019 virus is so comp lex and fast moving, any advice on how we at the Journal can help in the response would be great. Your advice is always appreciated as we all try to get it right and be responsive. Lindsey (b)(6) From: "Fauci, Anthony (NIH/N IAID) [E]" Dat e: Tuesday, February 4, 2020 at 7:06 PM To: "Baden, Lindsey, M .D." Cc: "Marston, Hil ary (N IH/ N IAID) [E]" (b)(6), "Conrad, Patricia (NIH/ NIAID) [E)" CbH6), "Lerner, Andrea (NIH/ NIAID) [E]" ~___;___ ..:....:,...:.....====:;~----::---"""":"".''."':':'":--- . CbH >, " Lane, Cliff (NIH/ NIAID) [El" CbH6) ---------- -------- --------- "Mo r ens, David (NIH/N IAID) [EJ' == (b)(6) Subject: RE: favor Lindsey: (b) (6). (b) (4) Best regar ds, Tony Anthony S. Fauci, MD Director Nat ional Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nat ional Institutes of Health Bethesda , MD 20892-2520 NIH-002 177 Phone : Cb )( FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . --------- From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) -------=- (b'""' )( =6) CbH ; Conrad, Patricia Cc: Marston, Hila ry (NIH/NIAID) [E) (NIH/NIAID) [E] (b)(6)> Subject: Re: favor Tony (and Hilary), Much appreciated Thank you, ---- ~=--c~= -------- (b)(6) . (b)(4). Lindsey From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16 PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" (NIH/NIAID) [E]" CbH6) Subject: RE: favor ---------- (b)(6) (b)(6), "Conrad, Patricia Lindsay : (b) (6). (b) (4) Tony Ant hony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bet hesda, MD 20892-2520 Phone : Cb)(6) NIH-002 178 FAX: (301) 496-4409 -------- (b)(6) E-mail: The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6)> Subject: favor Ton ~-------------------------- ~(b~~= (6)~. ~ (b)~(= ~ Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransm ission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or ent iti es other than t he intended recipient is unauthorized by the sender and is pro hibited . If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidential, privileged, and/or proprietary material. Any review, duplication, retransmiss ion, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than t he intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immed iately by return email and delete the original message from all computer systems. Thank you . Thi s email message is a private communication. The infomrntion transmitted, including attachments, is intended only for the person or entity to which it is addre ssed and may contain confidential, privileg ed, and/or propri etary material. Any review, duplication , retransmis sion, dis tribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this messagein error, please contact the sender immediatelyby return email and delete the origi nal mes sage from all compute r systems . Thank you. NIH-002 179 From: Date: To: Subje ct: Fauci,Anthony {NIH/NIAID) [El Wed, 5 Feb 2020 11:52:41 +0000 Conrad, Patricia {NIH/NIAID) [El FW: INTERVIEW-AHABER/A NEWS For discussion. From: GULSEN EDA ULUSOY _______ --------=-:-= Date: Wednesday, February 5, 2020 3:23 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: INTERVIEW-AHABER/A NEWS _, (b)(6) Dear Mr. Fauci, This is Eda Ulusoy from Turkey 's number one ranking news channel A Haber/ A News. We wou ld like to take few minutes of your ti me and kindly ask if we could possibly have the opportunity to make a Skype interview with you about China coronavirus outbreak. We can have the interview this week or next week. I can arrange it according to your programme. It will on ly take 15 minutes of your time. We would really apprecia t e if we can make this interview. Thank you for your kind consideration. I'm look ing forward to your reply. Sincerely, Eda Ulusoy Correspondent NIH-002 180 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:52:11 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview invitation from Dialogue CGTN :et us discuss. From: Bai Jacinta (b)(6) Date: Wednesday, February 5, 2020 2:58 AM ------------- To: Fauci, Anthony (NIH/NIAID) [E] (b)( 6) > Subj ec t : Interview invitation from Dialogue CGTN --==, (b)( >; Fauci, Anthony {NIH/N IAID) [E] Dear Mr. Fauci, This is Jacinta from Dialogue, CGTN of China Central Television. I hope this email finds you well. I'm reaching out to ask if you have time for a satellite interview at 6:30 am on Feb 6, Thursday, DC time. I read the interview to you on New York Times and sincerely wish that you could share more with our global audience. It would be our honor to have you on. Topics will cover the evolution of coronavirus and its mortality rate, difficulties in controlling the outbreak, cooperat ion in international communities, prevention measures and so on. Please kindly let me know if you are available for the show . I'll send the proposed questions beforehand and book the closest st udio for you. Appreciate it! Best, Jacinta Bai Dialogue, CGTN NIH-002 181 From: Date: To: Cc: Subje ct: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 11:34:46 +0000 Ho, David D. Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [Cl RE:2019-nCo\/ David: Thanks for the note. Please have your office contact my Special Assistant, Patty Conrad (copied here) to set up a call. I down at the Congress and White House most of the day, but we can probably squeeze a call in between meetings . Best, Tony From: Ho, David D Date: Tuesday, February 4, 2020 12:48 PM To: Fauci, Anthony (NIH/NIAID) [El Subject: 2019-nCoV (b)(6)> -------~~ (b)(6)> Tony, Greet ings. As you can see below, our institute has moved. We are now part of Columbia. Do you have a brief moment to chat about the new coronavirus? Best, David David D. Ho, M .D. Director, Aaron Diamond AIDSResearchCenter Clyde and Helen Wu Professor of Medicine Director, Wu Family China Center Columbia University Vagelos College of Physicians and Surgeons 701 W. 168th Street, HHSC1102 New York , NY 10032 NIH-002 182 Fauci, Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 11:17:05 +0000 Collins, Francis (NIH/OD) [El Cc: Harper, Jill (NIH/NIAID) (El;Johnson, Martin S. (NIH/NIAID) [El;Conrad, Patricia (NIH/NIAID) [El;Tabak, Lawrence (NIH/OD) [El;Shapiro, Neil (NIH/OD) [El;McGowan, John J. (NIH/NIAID) (b)( ;Auchincloss, Hugh (NIH/NIAID) [CJ (b)(6) Subject: RE:Coronavirus From: Date: To: --------- Francis: (b)(5) -------------- (b)(5) Happy to discuss further. Thanks, Tony From: Coll ins, Francis (NIH/OD) [El Date: Wednesday, February 5, 2020 5:58 AM ------~~ To: Fauci, Anthony (NIH/NIAID) [E;! ] ====== Cc: Tabak, Lawrence (NIH/OD) [El (b)(6) (b=-; )(~6)~ CbH6)>; Shapiro, Neil {NIH/OD) [El (b)(6) Subject: FW: Coronavirus Import ance: High Hey there Tony, (b) (5) Thanks, Francis From: Shapiro, Neil (NIH/OD) [El Se nt : Tuesday, February 4, 2020 8 :31 PM ----~~ To: Collins , Francis (NIH/OD) [El -------- (b)(6)> CbH6)>; Tabak, Lawrence (NIH/OD) [El Johnson, Alfred (NIH/OD) [El (b)(6); Wolinetz, Carrie ----:-~~:-====::L.:.--~~ (NIH/OD) [El (b)(6)> ; Hallett, Adrienne (NIH/OD) [E] (b)(6) Schwetz, Ta r,_ a -:-: (N -:-: l-:-: H/7 0:-::D:-:-)-:-[=: El:.:====---...,_ (b,.._.. ) =(6)> (b)(6)>; NIH-002 183 Cc: Shaya, Cecile {NIH/OD) [El _______ .... (b)(6) Subject: RE: Coronavirus Import ance: High (b)(5) From: Shapiro, Neil {NIH/OD) [El Date: Tuesday, February 4, 2020 4 :46 PM To: Collins, Francis {NIH/OD) [E]----- --=(b"'"" )(=6J>; Tabak, Lawrence (NIH/OD) [El (b)( ; Johnson, Alfred (NIH/OD) [El --~~~~====!:,__-~~ {NIH/OD) [El CbH6J ; Hallett , Adrienne (NIH/OD) _______ .... Schwetz, Tar ... a -:-: (N -:-: 1-:-: H/7 0:-:D :-:: )-:[ ::-: El:--====::.;__--,;,Cc: Shaya, Cecile {NIH/OD) [El Subject: RE: Coronavirus [El (b)(6)>; Wolinetz, Carrie (b)(6) (b"S"'" H=6) (b)(6) Francis, (b) (5) Neil NIH-002 184 From: Shapiro, Neil (NIH/OD) [E] Date: Wed nesday, January 29, 2020 2:34 PM To: Collins, Francis (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [El CbH ; Johnson, Alfred (NIH/OD) [El (b)(6)>; Wolinetz , Carrie ":""."'."".""."-:-:-:-:-:-:::-====~~-~.;., (NIH/OD) [El (b)( >; Hallett, Adrienne (NIH/OD) [E] (b)(6)> Subject: RE: Coronavirus I'm sending them the first part, thanks . From: Collins, Francis (NIH/OD) [E] (b)(6) Date: Wed nesday, January 29, 2020 5:23 AM -------~~ Shapiro, Neil (NIH/OD) [E) (b)(6) Johnson, Alfred (NIH/OD) [El CbH >; Wolinetz, Carrie -~---~==:=:!.. __ __:_~= (NIH/OD) [E) (b)( >; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: RE: Coronavirus To: Tabak, Lawrence (NIH/OD) [E) (b)(6) (b) (4) FC From: Tabak, Lawrence (NIH/OD) [El Date: Tuesday, January 28, 2020 6:25 PM To: Shapiro, Neil (NIH/OD) [E]------~= (b)(6) Collins, Francis (NIH/OD) [E] (b)(6)>; Johnson, Alfred (NIH/OD) [E] (b)(6); Wolinetz, Carrie (NIH/OD) [El (b)(6) ; Hallett , Adrienne (NIH/OD) [El (b)(6) Subject: Re: Coronavirus (b)(6) (b)(5 Larry (b)(6)> From: "Shapiro, Neil (NIH/OD) [E]" Date: Tuesday, Jan uary 28, 2020 at 5:31 PM To: Francis Collins (b)(6), "Tabak, Lawrence (NIH/OD) [E]" --------- CbH "Johnson, --------W o Ii net z, Carrie (N IH/OD) [E]" >, Alfred (NIH/OD) [E]" (b)(6) CbH >, "Hallett, Adrienne (NIH /OD) [E]" 11 (b)( Subject: Coronavirus (b)(5) NIH-002185 (b) (5) Neil NIH-002 186 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:18:25 +0000 To: Conrad, Patricia (NIH/NIAID) [El Subject: RE: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. No dinner. ---------- (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Se nt: Tuesday, February 4, 2020 11:21 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) Cc: Barasch, Kimberly (NIH/NIAID) ~ [c::.========-cc(b )'""(=6) Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. -------~~ See highlight - w ill you and ---- Cb>< · att end the dinner. Pis advise. Patricia L. Conrad Public Health Analyst and Special Assistant to the Director National Institute of All ergy and Infectious Diseases The National Institutes of Hea lth 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301 -496 -4409 fax Disclai mer: The informat ion in this e-mail and any of its attachments is confiden tial and may conta in sensitive information . It sh ould not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Marlene Colucci Se nt: Friday, January 31, 2020 2:00 PM To: Fauci, Anthony (NIH/NIAID) [E)-------= (b-c)(c-= 6) Cc: Conrad, Patricia (NIH/NIA ID) [El (b)( ; David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, NIH-002 191 On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meet ing on February 20-21, 2020 in Washington, O.C. The theme of the meeting is "The Next Decade." {See form al invitat ion attached as we ll as list of CEO members). We would like for you to part icipate in a 50 minute fireside chat wi t h David Rubenstein {and possibly Dr. Francis Collins) to discuss the current coronavirus as we ll as what we should expect in the next decade. We want to give our CEOsinsights into what the next 10 years will bring in terms of detection, diagnosis and t reatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and t ransportat ion. As you know, The BusinessCouncil is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy . We expect at least 150 CEO members, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best opportunity for you to meet our CEOmembers and spouses, speakers and othe r special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additiona l details and answer any questions you may have. We look forward to hearing from you and wou ld be honored to have you participate with us again. Warmest regards, Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I B 1 ~ USINESS COL \JClL T: 202-298-7650 C Cb)(6) F: 202-785-0296 NIH-002 192 From: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:17:19 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E] Subject: FW: Comment on story about how confident people feel about the ir govt's response to a health epidemic Date: To: Cc: Please try to draft a response for me. Thanks . From: Rajeshni Naidu-Ghelani Date: Tuesday, February 4, 2020 12:23 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b ..--. ),.., (6) = Subject: Comment on story about how confident people feel about their govt's response to a health epidemic Hi Dr. Fauci, I hope all is well. I'm working on a news story tied to the coronavirus outbreak and tying it to how people responded to a recent global lpsos poll about the threat of a major health epidemic in their country in the next 12 months . https ://www .ipsos.com/sites/defau lt/files/ct/news/documents/20 1911/ a-more -dangerous-world -fear-2019.pdf I was hoping to get your comments on this, considering your expertise in infectious disease control. Below are some questions. If you could respond via email, that would be great as I am on a tight dead line to get this story up. If it's easier to give you a call, I can do that as well. Please let me know what works best. The story will be published on lpsos.com, on social media and our various country webs ites. Thank you and I look forward to your response. 1. In our survey of more than 18,500 people in 28 countries done in late last summer, more than half (51%) of peop le said there was threat of a major health epidemic in their country in t he next 12 months w ith peop le in emerging markets at the top of the list. Are you surprised by this result? It's among the highest reading for this questio n since the Ebola outbreak in 2014 when the percentage climbed to 59%. 2. The U.S. is the only developed country in the top 10 list where most people think a major health epidemic will occur. Why do you think this is? 3. A follow up question to t he previous one is how confident people are that their government could protect them or respond effectively if such an outbreak was to occur. Over half globally said they were confident in their gov't's response. Do you think people have a lot of trust in those in power to do the right thing in times of an outbreak? 4. Seven of the top 10 countries where people had the most confidence in govts are in the developed world . How important are developed healthcare systems when it comes to outbreaks like the coronavirus? 5. Likewise, many countries at the bottom of this list are emerging markets. What can govts in these countries do to ease peop les' fears on how they are or will handle an outbreak like the coronavirus? NIH-002 193 6. How difficult is it for governments and health officials to prevent the spreading of a virus like this before it becomes a pandemic? What measures can be taken? Please free to add any add itional information that you thin k may be relevant . I hope to hear from you soon. Regards, Rajeshni RajeshniNaidu-Ghelani I Data Journalist PublicAffairs 160 Bloor Street East, Suite 300 M4W 189 Toronto - Canada Ctt,\NQE THE OAt.'!1 Phone: +1416 572 5143 Mobile: ,.._ __ ...>;;<~ rajesbni .naidu-ghe lani@ ipsos.com www .ipsos.com GAMECHANGERS II NIH-002194 From: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 04:12:18 +0000 Routh, Jennifer (NIH/NIAID) [E] Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E] Subject: RE:for review: responses for Elemental news site (not urgent) Date: To: Cc: I made some modifications. You can send it. Th anks. From: Routh, Jennifer (NIH/NIAID) [E) (b)( Date: Tuesday, February 4, 2020 4:11 PM To: Fauci, Anthony (NIH/NIAID) [E]______ > (b '"'~..-. (6) => Cc: Billet, Courtney (NIH/NIAID) [E] (b)(6),; Stover, Kathy (NIH/NIAID) [E] (b)( ; Conrad, Patricia (NIH/NIAID) [E] (b)( >; Folkers, Greg (NIH/NIAID) [E) (b)(6) Subject: for review: responses for Elemental news site (not urgent) Dr. Fauci This request is not urgent for today . The reporter Rob Britt (writes for Elemental, a health and wellness news site) reached out to you directly on Sunday with some questions about 2019-nCoV. I have drafted proposed responses for you in red below . Please let me know if you have edits. I will send responses back to the reporter attributed to you. Thanks, Jen From: Rob Britt (b) (6) Date: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E] ------------- ---..-,~ (b)(6J> Subject: Coronavirus - reporter's questions Hi Dr. Fauci: We are updating our coronav irus story periodically, keeping it factual and level-headed , and I have seen your comments on NPR Friday and in the NYTimes over the weekend , so I hope you could comment very briefly for our story: -- What's your expectation for whether this will become a pandemic? The nove l coronavirus ou tbreak will likely become a pandemic. We know the virus is very transmissible. The infection continues to accelerate and there is efficient transmission in china. If sustained transm ission also occurs in other countries throughout the world, the outbreak would fulfill the definitive of a pandemic -- Pandemic does not necessarily equate to a terrible situation, compared to, say bad flu seasons. What 's your expectation on the potential severity of this coronavirus? It is difficult to pred ict the severity at th is time. Even if the morta lity rate of a virus remains low , if it is easily t ransmissible, the global impact can be significant . -- And your suggestion to people in the U.S. who might be very concerned? NIH-002195 We are treating t he emergence of a nove l coronavirus as a very serious pub lic health threat. However , the risk to the general Amer ican publ ic remains low at this time . We understand that peop le may be wor ried . We ask that people not let fear or panic guide the ir actions . Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Writ er on Medium in Science & Health. Contributor to OneZero (science) & Elementa l (health). Former editor-in-chief of Live Science and Space.com. (b)(6) (b)(6) NIH-002 196 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 04:06:33 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: For Dr. Anthony Fauci {NIAID/NIH) - forward of my email letter to Dr. Gregory Poland (Mayo Clinic) regarding Chinese 15 minute Coronavirus test and other concerns To: Subject: Please handle. -----Original Message----From: Jon M (b) (61 Date: Tuesday, February 4, 2020 4:55 PM To: Fauci , Anthony (NTH/NlAID) [E] (b) ~ Subject: For Dr. Anthony Fauci (NIA i D/NlH) - forward of my emai I letter to Dr. Gregory Poland (Mayo C linic) regar ding Chinese 15 minute Coronavirus test and other concerns --------, a-s-r,= (b) (6} From: Jon M To: ocpostoffice @niaid .nih.gov Subject: Atten tion Meylin - Forward of my emai l lietter to Dr Gregory Poland (Mayo Clinic) for Dr Anthony Fauci (NlAID/NII-1} Date: Feb 4, 2020 I :45 PM Hello Meylin, Thank you for taking my call yesterday and forwarding the following email I sent to Dr. Gregory Poland care of his assistant, Joseph Roberts, to Dr. Fauci. Jon Markowitz From: Jon M (b) (61 To: (b)(6) Subject: JOE - We spoke on phone today ... Please forward my email with reference links to Dr. Gregory Poland Date: Feb 4, 2020 12:57 PM Hello Joseph Roberts (Mayo Clinic), We spoke on phone today ... Pleas e forward my email with reference links to Dr. Gregory Poland Tha nk you, Jon Ma rkowitz Feb 4 , 2020 Dear Dr. Gregory Poland I saw your appearance Feb 3 on a CNBC news program: https ://wvvw .youtube .eom/wa tch? v-=Wq33oZdO -R4 'We're basically at a pandemic now' : Mayo Clinic physician on corooavirus Fyi, I am not a doctor, nurse or medical student nor do I work in the medical field. I am a musician. I am 65 years old and live in Los Angeles. A news article publi shed on rt.com Feb 31, 2020 (see link below) announced the Chinese have developed a 15 minute test for the Corona virus, yet I've not seen or heard about this news anywhere else. [ bad heard there were efforts here to develp a faster test than what is being employed currently by the CDC, but believe its critical the NIH-002 197 White House arrange for the new Chinese test to be available in the US everywhere immediately. This news should have been mentioned by NIH doctor Anthony Fauc hi at the White House Briefing on Jan 31, 2020 but was not, nor was it mentioned by Mayor Di Blasio on Feb 1 at Bellevue Hospital in NY . At this point , the NTH, CDC and White Hous e shou ld have already obtained the Chinese 15 minute test for the virus and implement at all US medical centers and airports receiving travele rs from the infectious regions. Due to the exponential growth of infection rates from 'seed' individuals who are asymptomatic but don't know they are infectious, whether returni ng from infection zones or are infected by others already here, I am hoping you and other infect ious disease experts waste no time in vigorously pursuading the White House , NTH, CDC and all other agencies as to the necessity to test ALL travelers (not just those who are symp tomatic) coming into the country by air and sea with the Chinese 15 minute test as well as pull out all the stops to develop an eve n quicker test that's portable. As the numbers of infections increases exponentially in the US and other countries this next 2 to 4 weeks from increasing numbers of asymptomatic 'seed' individuals unknowingly spreading the disease , we are certainly on the precipice of an unstopable runaway epidemic. What is also desperately needed from the federal government are frank and honest recommendations regarding what is necessary to prevent becoming infected such as: surgical or constmction respirators that seal to the face, eye protection goggles, nitrile exam gloves, sanitizer wipes along with specific protocols on how not to bring the vims particles back to ones car, borne and possessions. It is imperative that manufacturing of EFFECTIVE respirator masks or equivalent non-disposable respirators be ramped up to huge scale. Without adequate numbers of these , exam gloves and eye protection this country will not be capable of containing this epidemic . Below this article, I've pasted in a number of useful you tube links of relevant and timely information in refere nce. Thank you very much for your attention to this issue. Jon Markowitz Los Angeles References: https://www .rt.com/news /4 79705-china-develo p-coronav irus-rap id-test/ China develop s rapid Coronavirus test that works in under 15 MINUTES 3 I Jan, 2020 I0:48 Scientists in China have reportedly developed an express test which can detect the 2019-nCoV novel coronavirus in under fifteen minutes , in a major breakthrough which will hopefully help stem the tide of infe.ction. Experts from a tech company based in Wuxi in eastern China's Jiangsu Province, working with the National Institute for Viral Disease Control and Prevention , developed the rapid nucleic test kit in ju st ten days, according to the Xinhua news agency. The test takes between eight and 15 minutes to produce a result and is currently being mass-manufactured at a rate of 4,000 kits per day, with the city government in Wuxi explo ring efforts to boost production even further. The first batch of kits has reported ly already been deployed to the frontlines at the epicen tre of the outbreak, Wuhan , in Hubei province. https://www .youtube.co m/watch?v= Wg33oZd0- R4 'We're basically at a pandemic now': Mayo Clinic physician on coronavirus 114,173 views NIH-002198 •Feb 3, 2020 CNBC Television https://www.youtube.com/watch?v=VdU i kwuw7T 11 confinned US coronavirus cases, experts warn of pandemic I ABC News 157,773 views •Feb 3, 2020 ABC News https://www .youtube.com/wa tch?v=8Hjy3UfaTSc Coronavirus Epidem ic Update 9: Fecal -Oral Transmission , Recove1y vs Death Rate 129,190 views •Feb 3, 2020 MedCram https://www .youtu be.com/watc h?v=GpbUoLvpd Co Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine , & MRSA 329,919 views •Feb 2, 2020 MedCram https://www .youtube.com/user/MEDCRAMv ideos/v ideos MedCram youtube channel [Dr. Roger Seheult - https://W'.vw.medcram .com/] https://www.youtube.com/watch?v=z05Z rMfKUDc Coronavirns , Contag ion and Complications 228 ,007 views •Feb 2, 2020 Dr. John Campbell https: //www.yo utube.com/watch?v=u7D3AoNdp84 Wuhan virus compared to MERS and SARS 45,569 views •Feb 3, 2020 Dr. John Campbell https://www.yo utube.com/user/Camp bellteaching/videos Dr. John Campbell youtube channe l https://www.youtu be.com/wa tch?v= zczkLZN 194 Mayor de Blasio Holds Media Availability 334 views Feb l , 2020 NYC Mayor's Office https://,vww .youtube.com/wa tch?v=oMl-9Kvoj7O Coronavirus: U.S. Declares Public Health Emergency , Will Quarantine China Travelers [White House Briefing] 121,648 views •Streamed live on Jan 3 l , 2020 QuickTake by Bloomberg NIH-002199 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAID) [El Wed, 5 Feb 2020 04:03:41 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus Wuhan Coronavirus Vaccine.docx Please handle. From: John Howard _________ Cb _>_<_ ·> Se nt : Tuesday, February 4, 2020 6:05 PM To: Fauci, Anthony (NIH/NIAID) [E]______ ..,, (b""" )(=6) Subject: coronavirus Dear Dr, Fauchi, I understand you are leading an effort on the Wuhan Coronavirus . I am writing to enquire how we may help in this effort. (b)(4 ,___ (b ,...,)"(4 ")" Thanks for your attention regarding this matter. Sincerely, John Howard, PhD President ABI (b)(6) NIH-002200 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 03:49:07 +0000 Fleisher, Thomas (NIH/CC/OLM) [V) RE: Question No problem. From: Fleisher, Thomas (NIH/CC/OLM) (V) Date: Tuesday, February 4, 2020 9 :37 PM (b) (6) > ------- To: Fauci, Anthony (NIH/NIAID) [E] -------=- Cb c-H= > Subject: Re: Question Tony, Would you be willing to have your statement "we are in the middle of influenza season..." included in the Academy 's on line Practi ce Matters email Thursday going out to all members (attri buted to you) along w ith a link to the CDCwebs ite devoted to Coronavirus? Than ks, Tom (b)( From: "Fauci, Anthony (NIH/NIAID) (E)" Date: Tuesday, February 4, 2020 at 3:14:47 PM To: "Fleisher, Thomas (NIH/CC/DLM) IV]"----- Cc: "Conrad, Patricia (NIH/NIAID) [E]" Subject: RE: Question > ~= --------- Tom: Right now nothing specific to communicate except that we are still in the middle of an influenza season and the things that we do to prevent spread of flu (i.e. hand washing, social distancing from crowds) are the same things that we would do if we have transmissions of nCoV here . Best, Tony Anthony s. Fauci, MD Directo r National Institute of Allergy and Infectiou s Disease s Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892 -2520 Phon e: (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail : -------- NIH-002201 The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Fleisher, Thomas (NIH/CC/DLM) [V] Date: Tuesday, February 4, 2020 1:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Question --------- (6)> ------~~ CbH6J> -------(b) Tony, I was asked if th ere is any message th at the A&I community should receive in regards to the curr ent Coronavirus outbreak in China and potential impact on the US. I recognize the CDC and state medical boards are releasing updates and recommendat ions but t he question posed to me was is there anything AAAAI should communicate to our membe rs? Thank yo u for considering this question. Regards, Tom NIH-002202 From: Date: Fauci,Anthony (NIH/NIAIO) [El Wed, 5 Feb 2020 03:48:11 +0000 To: Sylvia Burwell RE:A couple of quick quest ions. Subject: Sylvia: Masks are really for infected people to prevent them from spreading infection to people who are not inf ected rather than protecting uninfected people from acquiring infection. The typ ical mask you buy in the drug store is not really effective in keeping out virus, which is small enough to pass through the material. It might, however, provide some slight benefit in keep out gross droplets if someone coughs or sneezes on you. I do not recommend that you wear a mask, particu larly since you are going to a vey low risk location. Your inst incts are correct, money is best spent on med ical countermeasures such as diagnostics and vaccines. Safe travels. Best regard s, Tony From: Sylvia Burwell Date: Tuesday, February4, 2020 10:24 PM To: Fauci,Anthony (NIH/NIAID) [El Subject: A couple of quick questions . (b)(6)> ------~~ (b)(6) Begin forwarded message: From: Sylvia Burwell Date: February4, 2020 at 9:35:03 PM EST To: Sylvia Burwell (b)(6) (b)(6) Subject: Fwd: Advice re a donation EXTERNAL EMAIL : Use caution with links and attachments. Begin forwarded message: From: Sylvia Burwell Date: February 4, 2020 at 9:33:47 PM EST To: Tony Fauci (b)(6)> Subject: Fwd: Advicere a donation ----------- NIH-002203 (b)(6) Tony Two quick questions 1. I am travel ing to (b)(6) Folks are suggesting I take a mask for the airport. Is this something I should do. 2. Please see below. Do the Chinese have needs for support right now? Would money be better spent on diagnostics or vaccine work? Thanks! Sylvia Begin forwarded message: ---------- From: Richard Falkenrath Date: February 4, 2020 at 5:27:32 PM EST To: (b)(6) Sylvia Mathews Burwell (b)(6) (b)(6) Subject: Advice re a donation Hi Sylvia I hope this find you well. Quick quest io n, a little bit from left field, but drawing on your experience at Gates and HHS. Ray Dalio and Bridgewate r are interested in making a very sizable donation to help China deal with the globa l public health challenge arising from the new coronavirus. Any suggestions of where we should look to donate the funds? ----------- Thanks so much. forward to seeing you again soon. Richard (b)(6) NIH-002204 (b) (6) looking From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Wed, 5 Feb 2020 00:42:06 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Interview wi t h Voice of America Let us discuss. Anthony S. Fauci, MD Director National Institu te of Allergy and Infectious Diseases Bui ldin g 31, Room 7 A-03 31 Center Driv e, MSC 2520 National Institu tes of Health Bethe sda , MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipie nt. lf you have received this e-mail in eITor please inform the sender and delete it from your mai lbox or any other storage devices. The National Institute of Allergy and Infe ctio us Diseases (NIAI D) shall not accept liability for any statements made that are the send er's own and not expressly made on behalf of the NlAID by one of its representatives. -----Original Message----From: Rattaphol Onsanit Date: Tuesday, February 4, 2020 2:42 PM To: Fauci , Anthony (NlH/NlAID) [E] Subject: Interview with Voice of America ------~~ (b)(6) > Dear Dr. Fauci, l' m Chief of Voice of America 's Thai Serv ices. We met at the Thai Embassy on a Mahidol Award ceremony years ago. l' m now working on a news story about ho w developing countries equip themselves with medical readiness and policy responsiveness in the wake of the coronaviru s outbreak. T'm interested in this aspect because when T looked at Global Health Sec11rityIndex, Tha iland was ranked the highes t in its ability to tack le epidemics ahead of Japan , Korea and Singapore. It's also by far the highest among developing countries. I'm curious to find out about contributing factors for developing countries' readiness to effectively handl e an outbreak like coronavims. There may be some esse ntial aspects each counlTy can learn from one another during this outbreak and Thop e that this story cou ld shed lights on tha t. If you are free in the coming days, I would like to have an interview with you, if possible, on Skype. I would really appreciate the opportunity to spea k with you again. Thank you, Rattaphol Rattaphol "Ahn" Onsanil Chief of VOA Thai NIH-002205 Sent from my iPhone NIH-002206 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:31:31 +0000 To: Messonnier, Nancy (CDC/DDID/NCIRD/0D) Subject: FW: WSJ In Japan, a local bus dr iver in his 60s te sted positive aft er he drove tou rists from Wuhan, none of w hom had exhibited severe symptoms Nancy: See yellow highlight below . Did they misquot e the CDC? Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Folkers, Greg (NIH/N IAID) [E) -------Date: Tuesday, February 4, 2020 12:12 PM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6)> _,(b __)-,(6) = Subject: WSJ In Japan, a local bus driver in his 60s tested positive afte r he drove tour ists from Wuhan , none of whom had exhibited severe symptoms (b)( > From: Folkers, Greg {NIH/NIA ID) [E) Date: Monday, February 3, 2020 1:50 PM Subject: WSJ: Experts Race to Figure Out How Contagio us the Coronav irus Is -------- Experts Race to Figure Out How Contagious the Coronavirus Is NIH-002207 The outbreak of novel coronavirus appears more contagious than seasonal flu and is on par with SARS in 2002 and 2003, studies say China says that as of Saturday there were 4,109 infected people in the city of Wuhan . Photo: china daily/Reuters By Chao Deng and Jeremy Page Updated Feb. 2, 2020 7:34 pm ET BEIJING-Public-health experts around the world have been crunching numbers about the advance of China's dangerous new coronavi rus to estimate how far and fast it could spread. Studies pub lished in recent days say the new virus appears to be more contag io us than seasonal flu and on par with the simi lar pathogen behind an o utbreak of severe acute respiratory syndrome in 2002 and 2003. The new virus' mortality rate, however, is far below that of SARS. China says that as of Sunday there were 5,142 infected people in Wuhan, the locked-down city where the outbreak began. Some scientists estimate based on statistical models that the number could be in the tens of thousands. As health autho rities race to control the outbreak, they are also scramb ling to fi gu re out. based on imperfect data, how the virus is transmitted, the length of the incubation period and the degree to which people w ithout symptoms can spread the disease. China's health commission says incubation is generally between three and seven days, with the longest period being 14 days, and that people can spread the v irus before appearing ill. That makes a two-week NIH-002208 quarantine an important prevention measure-and casts doubt on the efficacy of temperature checks, the main screening method at immigration and other checkpoints. "For a given level of transmissibility, more asymptomatic transmission makes a disease harder to control," said Christi A. Donnelly, a professor at University of Oxford and Imperial College London. The U.S. Centers for Disease Control and Prevention, which warns against nonessential trave l to China, says it isn't clear how easily or sustainably the virus is spreading between people, but notes its abil ity to spread from infected patients without symptoms to close contacts within about 6 feet. A study led by a researcher from Boston's Northeastern University-using mathematical probability models based on travel patterns and confirmed international cases-estimated the median number of infections in Wuhan at 31,200 as of Wednesday, compared with that day's official tally of 2,261. Professors at the University of Hong Kong using similar methods published a study in the Lancet on Friday that estimated there were 75,815 infected in Wuhan as of Jan. 25, when official counts were still in the hundreds. "We think only 1 in 20 people who are getting infected are actually being diagnosed" in Wuhan, said Jonathan M. Read, lead author of a study from Britain's Lancaster University that also put Wuhan numbers in the tens of thousands as of Jan. 22. "It's quite a bit more transmissible than seasonal flu." Several recent studies published by scientists estimate that each person infected will, on average, infect two to three others. Epidemiologists call that the reproduction number . A reproduction number over 2 suggests an epidemic will expand rapidly, while below 1 suggests the problem is dwindling. Estimates of the reproduction number differ widely, with some studies using probability models and others based on regression analysis of cases over different time periods . Still, "they all point in the same direction," said Christian L. Althaus, an epidemiologist at the University of Bern in Switzerland who co-wrote a study estimating the basic reproduction number of the virus at 2.2. "There is a potential threat of a global pandemic if this reproduction number cannot be reduced." In Japan, a local bus driver in his 60s tested positive after he drove tourists from Wuhan, none of whom had exhibited severe symptoms . In Germany, four employees at an auto-parts supplier contracted the virus after attending a training session with a colleague from China, according to the company . The Chinese woman didn't exhibit symptoms, but started feeling ill on her flight home, where she tested positive for the new coronavirus. A study published in the New England Journal of Medicine study by Chinese authors including at the Chinese Center for Disease Control and Prevention says the virus spread between people as early as mid-December. The researchers analyzed 425 patients, with more than half of the cases linked to the Huanan seafood wholesale market where authorities believe the virus first spread to humans from wild animals. The researchers started identifying and collecting cases around the start of the year, by interviewing patients, relatives and other close contacts. They estimated the reproduction number at 2.2 and said that the majority of patients weren't hospitalized unti l after five days of being ill. Researchers of recent studies cautioned that even their estimates of the virus ' reproduction number are based on early and incomplete data and only assess its potential to spread before trave l restrictions and other control measures begin. Thereafter, the reproduction number can vary depending on those measures' effectiveness and other circumstances of the outbreak. Chinese officials have said the outbreak could peak or even begin to subside by Feb. 8, though some overseas experts have suggested the outbreak might not peak for several weeks. They note that the reproduction number doesn't necessarily predict an outbreak ' s severity, as many other factors come into play. Measles, for example, has a reproduction number of 12 to 18, but doesn' t spread that fast because there is a widely used vaccine. As yet, there are no vaccines for the new coronavirus, so Chinese authorities are relying on physical intervention measures, including locking down entire cities and forced quarantine . NIH-002209 Recent studies ind icate that stringent control measures will be needed not just in China, but in several other countries, to curtail the outbreak . "This is unprecedented both in terms of the virus and the control measures that have been put in place," says Adam Kucharski, associate professor at the London School of Hygiene and Tropical Medicine. - Raffaele Huang, Miho lnada and Ruth Bender contributed to this article. Write to Chao Deng at Chao.Deng@wsj.com and Jeremy Page at jeremy .page@wsj.com Copyright ©2019 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7blcdeb8 Disclaimer: Any third-party mater ial in this email has been shared for internal use under fair use provisions of U.S. copyright law , without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NTATD, NIH , HHS , or the U.S. government . NIH-002210 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Wed, 5 Feb 2020 00:05:35 +0000 Baden, Lindsey, M.D . Cc: Mars ton, Hilary (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E]______ Cb _H_6);Morens , David (NIH/NIAID) [E] Subj ect : RE: favor Att achment s: ------------(b ~)~(6) ~.~(b~)~ (4) Lindsey: (b)(6),(b)(4) Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Sent ; Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E]______ Cc: Marston , Hilary (NIH/NIAID) [E] _______ (b)(6) _,(__ b)..,.(6) """ Cb _>_C6) _ >; Conrad, Patricia (NIH/NIAID) [E] Subj ect : Re: favor Tony (and Hilary) , Much apprec iated . Thank you, Lindsey ------- (b)(6),(b)(4). NIH-002211 (b)(6) Fro m: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesday, February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAID) [E]" [E]" Subject: RE:favor (b) (6) ---------- Cb)( >, "Conrad, Patricia (NIH/N IAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301) 496-4409 (b)(6) E-mail : The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sende r' s own and not expressly made on behalf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M.D.< lbaden@ne jm.org> Se nt: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor -------- (b)(6) [~ (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidentia l, privileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, NIH-0022 12 please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary material. Any review, duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . NIH-002213 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 22:59:29 +0000 Lane, Cliff (NIH/NIAID) [E) RE: favor Thanks. Safe trave ls Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by on e of its represent atives . -------- From: Lane, Cliff(NIH/NIAID) [El Date: Tuesday, February 4, 2020 4 :31 PM To: Fauci, Anthony (NIH/NIAID) [El Cc: Marston, Hilary (NIH/NIAID) [El Subject: Re: favor (b)( > -------=-:~ (b)(6) .========~= ---------- (b)(6) (b) (6), (b) (4) --------- On Feb 4, 2020, at 9:13 PM, Lane, Cliff (NIH/NIAID) [E] NIH-002218 CbH6J>wrote: (b) (6), (b) (4) On Feb 4, 2020, at 8:46 PM, Fauci, Anthony (NI H/N IAID) [E] wrote: --------(b) (6), (b)(4) . Thanks. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the orig inal intended recipient. If you have received this email in error please Inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any sta tements made that are the sender 's own and not expressly made on beha lf of the NIAID by one of its representatives . -------- From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 3 :35 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Marston, Hilary (NIH/NIA ID) [E] Patricia (NIH/N IAID) [E] (b)(6) Subject: Re: favor ------~~ Tony (and Hilary), Much appreciated. Thank you , Lindsey (b)(6) >; Conrad, ----~~~=(b)(6),(b)(4) -------- From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Tuesd ay, February 4, 2020 at 2:16 PM (b)(6)> To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NI H/N IAI D) [E]" CbH6J ...:--==========~;;.. "Conrad, Patricia (N IH/NIA ID) [E]" Cb)(6) Subject: RE: favo r ---------- NIH-0022 19 (b)(6) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 ) 496-4409 (b)(6) E-mail: The information in this e-ma il and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have rece ived this email in error please inform the sender and delete it from your mailbox or any other storage devi ces . The National Institute of Allergy and Infectious Diseases (N IAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D.< lbaden@ne jm.or g> Date: Tuesday, February 4, 2020 12:31 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: favor --------- = (b)(6)> Ton (b) (6), (b) (4) Thank you for considering, Lindsey Th is email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may contain confidential, privileged, and/or proprietary mate rial. Any review, duplication, retransmission, distribut ion, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipient is unauthorized by the sender and is prohibited. If you have received this message in error, please contact the sender immediately by return ema il and delete the original message from all computer systems. Thank you. NIH-002220 This email message is a private communication. The information transm itted, including attachments, is intended only for the person or ent ity to which it is addressed and may contain confidential, privileged , and/or proprietary mater ial. Any review, duplication, retransmission , distribution, or other use of, or taking of any action in reliance upon, this informa t ion by persons or ent ities other t han the intended recipient is unautho rized by the sender and is prohib ited. If you have received this message in error , please contact the sender immediately by return email and delete the orig inal message from all computer systems. Thank you. (b) (6), (b) (4l NIH-002221 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:28:48 +0000 Seder, Robert (NIH/VRC) [E] To: Subject: (b)(6) Bob: -----------------------coronavirus. Hope to talk to you soon. (b)(6) I am drowning here in Best, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX : (301 ) 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002222 From: Date: To: Subj ect : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 21:0 1:39 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Media Request: CBCNews FYI Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Adam Miller Date: Tuesday, February 4, 2020 3:55 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) Subject: Media Request: CBCNews --------- (b)(6) Hi Dr. Fauci, I'm a senior writer with Canada's public bro adcaster, CBCNews, and I'm working on a national feature story about the containment efforts of the coronavirus outbreak and what future scenarios could be possible with the coronavirus globally. You spoke with my colleague Kelly Crowe by phone recently, and I'm hoping you could spare a few minu te s by phone to talk about the possibi lity and implications of the outbreak becoming endemic. Would it be possible to speak briefly by phone this week? I would only need a few minutes of your time and your expertise would be very beneficial for Canadians in the ir understand ing of this story . Thanks very much, Adam Adam Miller NIH-002223 Senior Digital Writer CBCNews Desk : 416-205-5719 Cell: (b)(6) Twitter : @adamsmiller NIH-002224 From: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 20:46:18 +0000 Date: To: (b)(6) FW: favor Subject: Attachments (b) (6), (b) (4) : (b) (6), (b) (4) CbH6).CbH 4J Thanks. Anthony S . Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX : (301 496-4409 E-mail : Cb) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M.D. Date: Tuesday, February 4, 2020 3:35 PM To: Fauci, Anthony (NIH/NIAID) [E) '====== Cc: Marston, Hilary (NIH/NIAID) [E] ------~~ (b== )(=-' 6)!-=-, Cb)( ; Conrad, Patricia (NIH/NIAID) [E) (b)(6) Subject: Re: favor Tony (and Hilary), Much appreciated . Thank you, Lindsey -------- (b) (6), (b) (4) (b)(6) From: "Fauci, Anthony (NIH/NIAID) [E]" Date: Tuesday , February 4, 2020 at 2:16--------PM To: "Baden, Lindsey, M.D." Cc: "Marston, Hilary (NIH/NIAID) [E]" [E]" (b) (6) ---------- Subject: RE:favor NIH-002225 Cb)( >, "Conrad, Patricia (NIH/NIAID) Lindsay: (b) (6), (b) (4) Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or igina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Baden, Lindsey, M .D. Date: Tuesday, February 4, 2020 12:31 PM To: Fauci, Anthony (NIH/NIAID) [E]_______ Subject: favor -------=---c-c= Cb _H_6) Ton (b) (6), (b) (4) Thank you for considering, Lindsey This email message is a private communication . The information transmitted, including attachments, is intended only for the person or entity to which it is addressed and may cont ain confidentia l, privileged, and/or prop rietary material. Any review, duplication, retransmission, distribution, or othe r use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited . If you have received this message in error , please contact the sender immediately by return email and delete the original message from all computer systems. Thank you . This email message is a private communication. The information transmitted, including attachments, is intended only for the person or entity to w hich it is addressed and may cont ain confidentia l, priv ileged, and/or proprietary material. Any review , duplication, retransmission, distribution, or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recip ient is unauthorized by the sender and is proh ibited. If you have received this message in error, please contact the sender immediately by return email and delete the original message from all computer systems. Thank you. NIH-002226 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 19:36:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Delivery Status Not ification {Failure) From: Date: To: Subject: Please t ake a look and handle. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone (b)(6) FAX: (301 496-4409 E-mail : (b)(6l The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Robert Knobler Cb)(6) > Date: Tuesday, February 4, 2020 1:36 PM -------~~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: Fwd: Delivery Status Notification (Failure) ------- --- Forwarded message -------- From: Mail Delivery Subsystem Date: Tue, Feb 4, 2020 at 1:30 PM Subject: Delivery Status Notification (Fai lure) To: (b)(6) -------------=""''"'"-=" (b) (6) ? • NIH-002231 Address not found Your message wasn't delivered to ------------ (b)(6) because the address co u Id n 't be found, or is unable to receive mail. The response fr om the remote server was: 550 #5 . 1 . 0 Address r e j ected . ------- --- Forwarded message -------- -From: Robert Knobler Cb)(6) (b)(6) Toi Cc: Bee: Date: Tue, 4 Feb 2020 13:29:23 -0500 Subject: Potential Coronavirus Prophylaxis Dear Dr. Fauci, You likely do not recall meeting me when I was looking at potential fellowships in 1978, however, I never forgot your enthusiasm. I went out to San Diego and worked with Mike Oldstone between 1979 and 11984. I did study a mouse coronavirus while there, mouse hepatitis virus (MHV) . I focused on genetic resistance, and eventually described a mouse locus for susceptibi lity, which coded for the MHV receptor. On to the present problem of human coronaviruses, Vaccines will take a long time for the current crisis. The angiotens in convertin enzyme 2 receptor has been ident ifed as t he relevant human coronavirus receptor. I am writing to suggest the investigation of ARBs as potential blocking agents to either reduce or completely block infection. Perhaps this can be checked. There may sti ll be sufficient untai nted suppl ies of ARBs, such as irbesar tan, available , or production can be scaled up, if t his truly is t he eve of a pandemic . Wish ing you success in th is endeavor. I am willing to cont ribu te in any way I can. Please feel free to contact me by e-mail or my cell phone . I did do clinical trial while with Mike, and then when I joined t he ----------- NIH-002232 neurology faculty of Jefferson in Philadelphia. I have been out on my own since December 1998, but I have never lost my interest in this work . I have some novel ideas on how HIV becomes AIDS, as well. All the Best, Robert L Knobler , MD, PhD (b)(6) (b)( Cell NIH-002233 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:54:25 +0000 To: 00~ Subj ect : FW: STAT: Quick retract ion of a faulty coro naviru s paper was a good moment for science http:/ /bit.ly/389QguM Heat her: As per our recent conve rsation. This is your story (see below). Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . The Watchdogs Quick retraction of a faulty coronavirus paper was a good moment for science By Ivan Oranskyand Adam Marcus February 3, 2020 NIH-002237 - -- ----• ,Hyacinth Empinado/STAT As fears of the novel coronav irus 2019-nCoV continued to spread last Friday, an inflammatory new paper appeared on bioRxiv, a preprin t server, where scientists post work that hasn't been vetted. Titled " Uncanny similarity of unique insert s in the 2019-nCoV spike prot ein t o HIV-1 gp120 and Gag," the paper claimed to find similarities between t he new coronavirus and HIV, the virus that causes AIDS. The use of the word "uncanny" in the t itle , together with "unlikely to be fortuitous" in t he abstract, led some to th ink that the authors were suggesting the virus had somehow been engineered by humans. The paper, from academic institutions in New Delhi, India, was critical and alarming, if true. Except that it wasn't. The paper was almost immediately withdrawn, but not before plenty of handwringing from researchers who comp lained that the appearance of such shoddy work on a preprint server without vetting by peer reviewers is precisely why the hoary old model of science publishing is better at keeping junk science out of the literature. Except that's not true, eit her. The old model has its advantages, to be sure, but it, too, is prone to the menace of pseudoscience, bad data, and other flaws - despite traditional academic journals' army of peer reviewers. And when these publications publish bad or erroneous research, it can take months or years for the papers to be corrected or retracted - if they ever are. In contrast, the reaction from the scientific community to the bioRxiv paper was swift. In a nutshell, commenters on bioRxiv and Twitter said, the author's methods seemed rushed, and the findings were at most a coincidence. By Saturday morning, bioRxiv had placed a special warning on all papers about coronavirus. Later Saturday, the authors commented on their paper, saying they were w ithdrawing it . And on Sunday, a more forma l ret raction appeared: "This paper has been withdrawn by its authors . They intend to revise it in response to comments received from the research community on their technical approach and their interpre tation of the results." All of that happened before a single news outlet with any reach covered the paper, as best we can tell. But none of it was quite fast enough for some critics. "This is why preprints can be bad," said one scient ist on Tw itte r. That scientist, Michael Shiloh, said he had even used bioRxiv to post preprints. "What bugs me about this preprint is that had this manuscript undergone legitimate peer review, these flaws would have led to a swift rejection and it wouldn't be contributing to the conspiracy theories and fear surrounding this outbreak," Shil oh cont inued . History suggests that Shiloh's confidence in peer review's ability to suss out pseudoscience may be a bit misplaced . The fraudulent 1998 paper that set off the vaccine-autism scare was published in The Lancet, one of the world's leading peer-reviewed medical journals. Other examples - including a paper by an NIH-002238 intelligent design advocate questioning the validity of the second law of thermodynamics as it pertained to evolution - abound . Papers claiming a link between autism and vaccines pop up near ly every year. Preprints can fill a void in times of rapidly changing science And even when peer-reviewed jou rnals do realize they've been had, retractions can take months or years. The Lancet took 12 years. Another journa l took five years to retract a paper claiming that HIV did not cause AIDS. We could go on, and the list includes papers that have never even been corrected. Those who claim preprint servers are dangerous because they lack peer review - bioRxiv has a perfunctory screening process - sometimes acknowledge that journals have had to speed up their game to meet the pressures of an outbreak like coronavirus, or SARSin the early part of this century. Angela Cochran, president of the Society for Scholarly Publishing, a trade group for publishers, said on Twitter : "Earlier this week, folks celebrated that coronavirus papers were popping up in preprint servers. Now there is a reminder not to use them to guide clinical practice because they haven't been reviewed. Journals ARE reviewing coronavirus papers and getting [them] pub'd quickly." Kent Anderson, another publishing industry veteran, put it more bluntly: "Journals Win The Coronavirus Race." Publishers have been looking for ways to score points against - and shut down - preprints for at least half a century . Journals have speedily published a number of important papers on the new coronavirus already, no doubt. Publishing industry champions are often quick to say that speedy peer review does not mean sloppy peer review - even in cases that requ ire massive correct ions. It now turns out that one of the world's leading peer-reviewed medical journals, the New England Journal of Medicine, pub lished a lette r last week about apparent coronavirus transmission from an asymptomatic person that turns out to be wrong . Such letters to the editor are not typically peerreviewed, or at least not as rigorously as a full study. But it's a glaring example of how a peer-reviewed journal can end up getting things wrong. Now we get to wait and see how long it takes NEJM to correct the record. We'll see whether peer-review champions, who are often unwilling - with some notab le and we lcome exceptions - to acknowledge how slow and ineffective correction in science can be, note this apparent failure of one of their gatekeepers. Doing so might, after all, make some people question the expe nsive subscript ion deals universities agree to w ith publ ishers, as well as the article processing charges that can run into the thousands of dollars for open access publications. Peer review can add a valuable filter. But those who work in publishing seem to be so wedded to the existing process that they can't admit its fl aws - or that it might be a good idea to also embrace preprint servers that could upend their business models. Just like in politics, maybe it's time to agree that the publishing process is a messy one, and stop using single episodes, free of context, to score points against one's rivals. This article has been updated with information about a flawed report in the New England Journal of Medicine. Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily represent my views nor those of NIAID , NTH, HHS, or the U.S. government. NIH-002239 From: Date: To: (NIH/NIAID) [E] Cc: (NIH/NIAID) [E];Lerner, Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 15:03:33 +0000 Mascola, John (NIH/VRC) [E);Graham, Barney (NIH/VRC) [E);Erbelding, Emily Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert Andrea (NIH/NIAID ) [E] Universal coronavirus vaccine (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone: (b)(6) FAX: (301) 496-4409 E-mail: (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) sha ll not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-00224 0 From: Fauci, Anthony (NIH/NIAIO) [E) Date: Tue, 4 Feb 2020 14:32:42 +0000 To: Greg Folkers (b)(6));Marston, Hilary (NIH/NIAID) [E];Eisinger, Robert (NIH/NIAID) [E];Lerner, Andrea (NIH/NIAID) [E] Subject: FW: Coronavirus Att achments: JVP200014(1).pdf, Coronavirus clean ve rsion 2-3-2020pbf-DCA.docx, JVP200011(1). pdf FYI. Confid enti al for now Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : Cb)(6) FAX: (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIA ID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Howard Bauchner Date: Tuesday, February 4, 2020 9 :19 AM To: Fauci, Anthony (NIH/NIAID) [E] (bH > Subject: FW: Coronavirus ------ -==-- Tony See attachment- accepted case series - likely to be pub lished Friday - after we talk - but like ly to mention it on Thursday - thought you should see it . HCB From: Howard Bauchner Date: Tuesday, February 04, 2020 7:23 AM To: Annette Flanagin ; Christiansen, Stacy ; Christopher Muth ; Demetrios Kyriacou ; Edward Livingston CbH6>>; Fontanaros, Phil ; GoIub, Robert ; Gregory Curfman --------------- NIH-002241 ; howard.bauchner@jama-archives.org ; Jody Zylke ; McDermott, Mary (b)(6)>; Mike Berkwits ; (b)(6); Anne Cappola (b)(6)> ; Basch, Ethan Marti (b)(6)>; David Mark ; Demetrios Kyriacou ; Derek Angus (b)(6)>; Feero, Greg CbH >; George O'Connor (b)(6) Goff, Donald (b)(6)>; Jeff Savei (b)(6) (b)(6); Joynt Maddox, Karen (b)(6) Preeti Malani (b)(6)>; Robert Golub ; Saitz, Richard (b)(6) Schrag, Deborah,M.D. (b)(6) Tom Cole (b)(6)>; Winkel mayer, Wo lfgang C. (b)(6); (b)(6) Armstrong, Katrina,M .D. (b)(6); Eric ; Cutler, David --(b)(6J>; Goldman,Lee (b)(6)JohnWong Eu Li (Div Head, Med Dept) >; Josh ......:.c========~~,;-" Sharfstein (b)(6)>; Julie Freischlag, M.D. (b)( ; Merchant, Raina (b)(6)>; 'Rodgers, Griffin (NIH/NIDDK) [E]' (b)(6); Steven E. Nissen (b)(6)>;Vokes, Everett [MED] (b)( Zeke ----=-.========~--------===========~--Emanu eI (b)(6)>; Andy Josephson (b)(6) (b)(6) (b)(6) Bonow, Robert, M.D. ------------ =====-~;"""'."' ~-.:-:=======~ ~ ':-:---:::--~=====~--~ ~ ------=--:-:-= -----.=======~~-----_.:..__..!=====~~~ Bressler, Neil (b)(6); Dimitri A. Christakis, MD, MPH (b)(6) ---------- >; Disis, Nora (b)(6)>; Fred Rivara, MD =====-_;__.,;__ _ _.::::======~::;:;;--=-.... (b)(6); Ongur, Dost -; R ::". i:-ta-=Re - d-:-:b-e-rg-,-:M -:-=D.:::::::==~ ======== (b)(6) (b)(6)l_ >; Shinkai, Kanade (b ~ )- (6) ~ Subject: Coronavirus So a quick update. Attached is a VP that will go up tomorrow - information for clinicians by Carlos del Rio and Preeti. They worked on it this weekend - thanks to both . Attached is a VP from Don and Ken Shine that came in before the epidemic/pandemicrelated. Going up this week. but is definite ly - it will be published on Friday. A big thank you to Phil and Derek. A Rl has also been accepted - it wi ll go up Thursday. I cannot thank Stacy and her team (and publishing)- everyone has been working overtime to process manuscripts in record time, put up a microsite; add CME for US clinicians; etc . Mike (and his team) and Ed have been a big help. As we have done in the past everything wi ll be free to the world. NIH-002242 I am interviewing Tony Fauci again on Thursday- the last podcast, video has close to 150K views- Tony - as I have said many times - is a national treasure. (b) (4) All that said we are definitely interested in novel research report (many can be research letters) . Just let me know . HCB Howa rd Bauchner, MD Edito r in Chief, JAMA and The JAMA Network Email: howard.bauchner@ jamanetwork.org Telephone: 312-464-2400 Please respect the confidential nature of this email. For my chats wi th authors please see: https :// jamane two rk.com/journa ls/ jama/pages/jama -autho rinte rviews NIH-002243 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 14:09: 40 +0000 Billet, Courtney (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E] Haskins, Melinda (NIH/NIAID) [E);NIAID OD AM RE:Thanks and filming I am leaving it up to you all to determine what is doable, feasible and/or appropr iate . We can discuss at our OD AM meeting . Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Billet, Courtney (NIH/NIAID) [E] _______ Cb _H_6) Date: Tuesday, February 4, 2020 8:42 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= ______ Cb _H_ ; Conrad, Patr icia (NIH/NIAID) [E) (b)(6)> Cc: Haskins, Melinda (NIH/NIAID) [E)_______ Cb H _.>; NIAID OD AM _ Subject: RE:Thanks and filming (b) (4), (b) (5) (b)(4), (b)(5) Just to kee in mind: _______ From: Fauci, Anthony (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6 :42 AM To: Conrad, Patricia (NIH/NIA IO) [E) Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: RE:Thanks and filming ..., (b)(6) -------~~ ----------------- (b)(6)>; NIAID OD AM (b)( > NIH-002244 OK -------- From: Conrad, Patricia (NIH/NIAID) [E] Date: Tuesday, February 4, 2020 6:35 AM To: NIAID OD AM Cc: Haskins, Melinda (NIH/NIAID) [E] Subject: Fwd: Thanks and filming --------- For discussion. (b)(6)> (b)(6) ------------------------ (b) (4). (b) (5) Sent from my iPhone Begin forwarded message: From: Janet Tobias Date: February 4, 2020 at 6:28:24 AM EST --------~~ To: "Conrad, Patricia (NIH/NIAID) [E]" CbH6> Cc: "Robinson, Whitney (NIH/NIAID) [CJ" .....;. __ ..:...:,_:_.===~:;;;------- (b)(6) "Barasch, Kimber Iy (NIH/NIAID) [C]" CbH6)> Subject: Re: Thanksand filming -:-:-:.===========--=-=-= (b)(4) Janet Sent from my iPhone On Feb 3, 2020, at 12:27 PM, Conrad, Patricia (NIH/NIAID) IE] CbH > wrote: --------- Just called you . sorry crazy morning Call me a .__ _____ _ Cb)(6) _ they can pull me from a meeting Patricia L. Conrad Public Health Analyst and Special Assistant to the Director Nat ional Institute of Allergy and Infectious Diseases NIH-002245 The National Institutes of Health 31 Center Drive, MSC 2520- Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in e rror please inform the sender a nd dele te it from your mai lbox or any other storage devices . National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender 's own and not express ly made on behalf of the NIAID by one of its representatives. From: Janet Tobias Date: Monday, February 3, 2020 8:43 AM To: Conrad, Patricia (NIH/NIA ID) [E) --------~= Subject: Re: Thanks and film ing ---------- Patty can I call you quickly about something-wil CbH6J> l take 3 m inutes. Sent from my iPhone On Jan 30, 2020, at 10:02 PM, Conrad, Patricia (NIH/NIAID) [E] CbH6J> wrote: It's been super busy. Will group with others tomorrow and get back to you. Sent from my iPhone On Jan 30, 2020, at 7:51 PM, Janet Tobias wrote : Hi Patty: Thanks for arranging the phone call. CbH4) (b) (4) NIH-002246 (b) (4) Never a dull moment in your world! Janet NIH-002247 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:58:53 +0000 Sylvia Burwell RE:Travel restriction policy Thanks, Sylvia. I miss our late night phone calls during the Ebola and Zika crises. It was tough , but we got it right. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Sylvia Burwell (b) (6) Date: Tuesday, February 4, 2020 8:32 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE:Travel restr iction policy ------ ::;..,..-,= CbH6J> Tony, Thanks so much fo r sending this AND for your very valuable time on Sunday. Our students that returned last week are in self-quarantine ... let me know if I can be helpful to you in any way . Best, Sylvia From: Fauci, Anthony (NIH/NIAID) [E]_______ Cb _H_6J Date: Monday, February 3, 2020 7:04 PM To: Sylvia Burwell Cb)(6) Subject: Travel rest riction policy NIH-002248 EXTERNAL EMAIL : Use caution with links and attachments. Sylvia: You probably already have this information, but here is the official policy as pe our recent discussion (see link). https :// china.usembassy-ch ina.o rg.cn/procla mat ion-on-suspension-of-e ntry-as-imm igra nts-andnonim migrants-bof-persons-who-pose-a-risk-of-transm itt i ng-2019-novel-coronavi rus/ Best regards , Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have rece ived this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002249 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 202013:07:15 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: Phone interview request from Seoul, Korea Let us di scuss. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail Cb)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------ From: The Scoop tbs eFM Date: Tuesday, February 4, 2020 6:06 AM To: Fauci, Anthony (NIH/NIAID) [E) Cc: (b)(6) (b)(6) -------~~ --------- (b)(6) Subject: Phone interview request from Seoul, Korea Hello, Dr. Anthony Fauci. This is Seyoung, a writer of an English radio show, The Scoop, in Seoul, South Korea. We deliver local and international trend ing news to English speaking listeners around the world . We'd like to invite you to talk with us on the phone for a special interview regarding the novel coronavirus outbreak. If you are interested and available to talk to us through a phone call at 10;30 am Friday or Saturd ay this w e e k, OR sometime betwee n 9:30 and 10:30 am next Mond ay, please let us know. And if you're not available for the given time, please also let us know other times feasible for you . The interview will run for about 10 minutes and you'll get your questions in advance. If you could provide your knowledge that is essential especially at this time, it'll be highly appreciated. NIH-002250 I look forward to hearing from you soon . Thank you very much . Seyoung Lee NIH-002251 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 13:05:59 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV: potential infection on CD4 cells. Insert positions in HIV gp120.pdf Please have someone respond to this person. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: (b) (6) Date: Tuesday, February 4, 2020 2:07 AM ------~~ -------infection on CD4 cells. To: Fauci, Anthony (NIH/NIAID) [E) Subject: 2019-nCoV: potential (b)(6) Dear Dr. Fauci, As you reali ze d the Indian resea rche r published a paper few days ago entitled "Uncann y similarjty of unique inserts in the 2019-nCoV spike prote in to HIV-I.gp120 and Gag", which was latterly withdrawn due to the controversial indication. I did a quick SWISS-MODEL on line calcu lation. Page 1-3 of the attachm ent show the flexible loops of insertion "1", "2", and "3" originally from V4, V5 and Vl ofHIV-1 gp120, respectively. But they are in presence on the spike protein of both bat and 20 19 corona virus (page 4 and 6). These inse rtions are potential CD4 binding domains (no proof yet but highly likely) and spatially won't interfere with ACE-2 binding domain (both SARS and 2019 coro navirus targetACE-2, page 5 and 6). In another word, the 2019 virus could be poten tially dual-targeting, infecting the lung and potentially CD4 T cells too (like HIV, see page 6) ! It is VERY URGENT to have clinicians follow up the confirmed cases such as by isolating their CD4 cells and doing RT-PCR. Please reach out to them. Rese arch labs including mine after obta inin g Spike protein of 20 19-nCoV shall examine its interaction with CD4. NIH-002252 Thank you for your immediateattention.Please keep me anonymous. God bless us, (b)(6J NIH-002253 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 12:36:50 +0000 Collins, Francis (NIH/OD) [E] names for W HO working group Francis: Derek Kan, Acting Deputy Director of 0MB and a member of the President's Coronavirus Task Force called me last night and in a very nice way said he would like to send me a list of names for consideration to be on the working groups to examine the evo lution of the nCoV. He worked as an executive in biotech prior to joining the USG and knows these individuals well. They are all people that we know and so I am just passing them on to you for our consideration. (b) (5) Thanks, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail : (b)( 6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represe ntatives . NIH-002254 From: Date: To: Subject: Fauci,Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 11:43:36 +0000 Conrad, Patricia (NIH/NIAID) [E) FW: REQUEST FORA TV INTERVIEWON WION TV INDIA Let us discuss. From: Latika Chugh {WION) Date: Tuesday, February 4, 2020 5:15 AM To: Fauci,Anthony (NIH/NIAID) [E]-------= (b-c)(c-= 6) Cc: Wion Guest Relations Subject: REQUEST FORA TV INTERVIEWON WION TV INDIA Dear Anthony S. Fauci, M.D., NIAID Director Greetings from WION! World Is One News (WION)is an international English news channe l from the Zee Med ia Group, Ind ia's premier te levision brand . WION is uniquely positioned as the 'Global Voice of India', presenting its own perspective on internationa l issues of critical significance. WION is the preferred channel for most opinion makers across the world as they happily attend our shows bringing in credible viewpoints on many issues. WION is currently available in Ind ia, Indonesia, The Republic of Philippines, Australia, Vietnam, Hong Kong, UAE, Malaysia, Singapore and South Africa etc. W ION's shows have featured Indian Political scenario & global leaders speaking on issues facing their country and the world in general. I would like to request for your ti me for an interview with us anytime soon today for 10-15 minutes. We usually conduct Interview via Skype. Request you to share your Skype Id. It's regarding CORONAVIRUS. Please let us know when is the best time for you t o join us via Skype. Waiting for your confirmation. CLICKHERETO WATCH WION LIVE: http s://www .wion ews.com/live-tv l Live TV, News I wionews.com NIH-002255 © 1998-2019 Zee Media Corporation Ltd (An Essel Group Company), All rights reserved . www .wionews. com Look fo1ward hearing from you . Reg ards Latika Chugh WION TV , India Zee Disclaimer: Confident iality/ Proprietary Note : This communicat ion is confident ial /propr ietary and is intended for use on ly by the addressee. Zee Med ia Corporation Ltd. accepts no responsibility for any mistransmission of, orinterference with, th is communication NIH-002256 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 03:02:57 +0000 To: Shalimar Adorno Conrad, Patricia (NIH/NIAID) [E);Barasch, Kimberly (NIH/NIAID) [CJ RE: Message from Dr . Jim Yong Kim Cc: Subject: Shalimar: Than k you for your note. I certainly will speak with Dr. Kim. My schedule is packed due to the coronav irus situation, and so please contact my Special Assistant , Patty Conrad (copied here and at (b)(6) to squeeze in a time that works for Jim and me. Thank you. Best regards, Tony From: Shalimar Adorno Date: Monday, February 3, 2020 6:33 PM (b)(6) ------~~ -------Dr. Jim Yong Kim To: Fauci, Anthony (NIH/NIAID) [E] Subject: Message from (b)(6) Good evening Dr. Fauci, I am writing on behalf of Dr. Jim Yong Kim who would like to have a call with you tomorrow. Can you please advise if you have any availability ? Kindly, Shalima r Adorno Assistant Vice President Globa l Infrastructure Partners 1345 Avenue of the Ame ricas . 30th Floor New York, NY 10105 T (b) (6) .______ (b = )~(6) = NIH-002257 Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:14:05 +0000 Collins, Francis (NIH/OD) [E] RE: Coronavirus From: Date: To: Subject: (b) (5) Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Collins, Francis (NIH/OD) [E] --------February 3, 2020 7:26 PM (b) (6) > ________ Date: Monday, -------~~ To: Fauci, Anthony (NIH/ NIA ID) [E] Subject: FW: Coronavirus From: Shapiro, Neil (NIH/OD) [E] _. (b)(6) (b)(6) Date: Monday, February 3, 2020 6:02 PM To: Collins, Francis (NIH/OD) IE] (b)(6) Tabak, Lawrence (NIH/OD) [E] CbH6l;Johnson, Alfred (NIH/OD) [E] (b)(6) Wolinetz, ....... ---:---:---""."':"'"""".""".:--:":===:..--__;--=--=-~ Carrie (NIH/OD) [E] (b)(6)>; Hallett, Adrienne (NIH/OD) [E] ------~= (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus --------- (b)(6) NIH-002258 (b) (5) From: Shapiro, Neil (NIH/OD) [E] Date: Monday, February 3, 2020 4 :05 PM -----~~ To: Collins, Francis (NIH/OD) IE] (b)(6)>; Carrie (NIH/OD) [E] (b)( >; Tabak, Lawrence (NIH/OD) [E] Johnson, Alfred (NIH/OD) [E] (bH6J>; Hallett, Adrienne (NIH/OD) [E] (b)(6)>; Wolinetz, (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: RE: Coronavirus -------- (b)(6) (b)(S) From: Collins, Francis (NIH/OD) [ E] (bH6J> Date: Monday, February 3, 2020 1:48 PM To: Shapiro, Neil (NIH/OD) [E] (b)(6)>; Tabak, Lawrence (NIH/OD) [E] (bH >; Johnson , Alfred (NIH/OD) [E] (b)(6J Wolinetz, Carrie (NIH/OD) [E] (bH >; Hallett, Adrienne (NIH/OD) [E] -----~~ (b)(6) Cc: Shaya, Cecile (NIH/OD) [E) Subject: RE: Coronavirus -------- (b)(6) NIH-002259 (b)(5) FC From: Shapiro, Neil (NIH/OD) [El Cb)( > Date: Monday, February 3, 2020 11 :33 AM -----~~ To: Collins, Francis (NIH/OD) IE] CbH6b ; Tabak, Lawrence (NIH/OD) [E] CbH6)>; Johnson, Alfred (NIH/OD) [El CbH6); Wolinetz, Carrie (NIH/OD) [E] CbH6)>; Hallett, Adrienne (NIH/OD) [E] (b)(6) Cc: Shaya, Cecile (NIH/OD) [E] Subject: Coronavirus Importance: High (b)(6)> (b)(5) Neil NIH-002260 From: Date: To: Cc: Patricia (NIH/NIAID) [E] Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 01:08:37 +0000 Kai Kupferschm idt Greg Folkers ------- --=~ (b)(6);Billet, Courtney (NIH/NIAID) [E];Conrad, RE: coronavirus quick question Kai: Error in my statement to you. I meant to say that " ......most t ransmissions occur from someone who is symptomatic" - not asymptomatic. I am really tired . Not much sleep these days. Best, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A -03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone: (b)(6) FAX:(301 496-4409 E-mail : (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. --------------- From: Kai Kupferschmidt Date: Monday, February 3, 2020 7:37 PM To: Fauci, Anthony (NIH/NIAID) [E] Cc: Folkers, Greg (NIH/NIAID) [E] ...:.======~ (b)(6) =--c= (b)~(':.ai ; Billet, Courtney (NIH/NIAID) [E] Subject: Re: coronavirus quick question Thanks Tony, this is interesting and I'm sorry I didn't have more time to get a comment from you . I can only imag ine your workload at the moment. I will include comment from you now . Best Kai NIH-002261 On 4. Feb 2020, at 01:29 , Fauci, Anthony (NIH/NIAID) [E]....______ (b_H_. 6)>wrote: Sorry that I got to this so late . I have been swamped. I just read your story in Science. It is unfortunate that they did not interview the patient. Obviously, this changes the conclusion of the paper. My comment: "There1 s no doubt after reading [the NEJM] paper that asymptomatic transmission is occurr ing" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no publication came out and said this. Since th is was the first publication supposedly documenting this phenomenon, that is why I referred to the paper and made my comment. It is unfortunate that this error was published, but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my col leagues in China who is a highly respected infectious diseases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect, but according to reputable Chinese scientists , my statement is correct . Having said that, I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmissions occur from someo ne who is asymptomatic. Best regards, Tony NIH-002262 From: Fauci, Ant hony (NIH/NIAID) [E) Tue, 4 Feb 2020 00:37:32 +0000 Conrad, Patri cia (NIH/NIAID) [E) RE: Tony and Conronavirus Date: To: Subject: Set up a caLIfor me with Ed Henry Anthony S. Fauci , MD Director National Ins titute of Allergy and Infectious Dise ases Building 31 , Room 7 A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone: (b) (6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. l f you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not express ly made on behalf of the NlA ID by one of its representatives. -----Original Message----From: Conrad, Patricia (NIH/NIAID) (E] Date: Monday , February 3, 2020 12:28 PM To: Fauci, Anthony (NlH/NlAID) [E] ---------------~~ (b)( 6) (b) (6} -------- (b)( 6) > ; Folkers, Greg (NlH/NIAID) (E] Subject: FW: Tony and Conronavirus f irm for Feb 11 ASF will you cancel DDCF or do r need to? Please advise Patricia L Conrad Public Health Analyst and Special Assistant to the Director National Institute of Allergy and Infectiou:sDiseases The National Institutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)( 6) 30 1-496 -4409 fax Disclaimer: The information in this e-mail and any of its attachments is confidential and may contain sensitive infom1ation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in eITor please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NIAID by one of its representatives. -----OriginalMessage----From: Katz , Ruth Date: Monday , f ebr1.1a1y3, 2020 12:20 PM NIH-002263 ---------- To: Conrad, Patricia (NIH/NWD) [E] Cc: Katz, Ruth Subject: RE: Tony and Conronavirus (b)( We have a room on the 11th. Ron is available and holding the date. Think time would work for you guys. Time wou ld be over lunch. At tendees arrive around 11:30 to grab lunch. Program sta rts at noon and runs to about II : 15. Of course , Tony is more than welcome to come in time for lunch. But he need not actually arr ive until shortly before noon so we can mike him up. J might also try to get someone from CDC 10 round out the discussion. But if only Tony and Ron, we will run with it. Also need to line up the moderator. But that shouldn't be a problem. Would run options by you first. Our comms team is really interested in pushing this -Ruth RUTH J. KATZ Vice President, Aspen Institute Executive Director, Health, Medicine and Society Program The Aspen Institute rnth.katz @a speninstitute .org 202-736-5827 -----Original Message----- ---------- From: Conrad, Patricia (NIH/NTAJD) [E] Date: Monday, February 3, 2020 11:57 AM To: Katz, Ruth Subject: RE: Tony and Conronavirus (b)(6) > Tf you have a room and Mr. Kia in is available on Feb 11 - please let me know. Best between 11 am - 3 or 4 pm Let me know Patricia L. Conrad Public Health Analyst and Specia l Assistant to the Director Natio nal Ins titute of Allergy and Infectious Disea ses The National Institut es of Health 31 Center Drive, MSC 2520 - Room 7 A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices. National Institute of Allergy and Jnfectious Diseases (NJAID) shall not accept liability for any statement made that are sender 's own and not expressly made on behalf of the NIATDby one of its representatives. -----Original Mes:sage----- From: Katz , Ruth Date: Monday , Fcbniary 3, 2020 11:43 AM To: Conrad, Patric ia (NIH/N IAID) [E] Cc: Katz , Ruth -------r:,,:,~(b)(6) > NIH-002264 Subject: RE: Tony and Coruonavirus Hi Patty, Thanks :so much and understand comple tely. Can only imagine how crazt:: Subject: RE: Tony and Conronavirus ---------- (b)(l>t Hi Ruth - circling back - hope we can make this work - will get back to you in a day or two .... Patr icia L. Conrad Pub lic Health Analyst and Specia l Assistant to the Dir ector National l nstitu te of Allergy and Infectious Di seases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infonnation in this e-mail and any of its attachments is confidential and may contain sensitive infonnation. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that are sender's own and not expressly made on behalf of the NlAlD by one of its representatives. ----- Original Message- ---From: Conrad , Patricia (NlH/NIAID) [E] Date: Monday , Feb ruary 3, 2020 8:40 AM To: Katz , Ruth Subject: RE: Tony and Conronavirus Hi - sorry for the delay - its been insane ly busy . NIH-002265 He would love to do this but our schedu le has been changing literally by the minute - so much so that we have had to cancel meetings , events and 2 trips he had scheduled for out of town last week. So - whi le he would love to do this and would make himself available ... it might be better to do later when things hopefuJly quiet down a bit. Defer to you tho as to when you want to do your event. Happy to chat more .... Patricia L. Conrad Public Health Analyst and Special Assistant to the Dir ector National Institu te of Allergy and Infectious Diseases The National Inst itutes of Health 31 Center Drive, MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496-4409 fax Disclaimer: The infom1ation in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recip ient. If you have received this e-mail in error please inform the sender and delete it from your mailbox. or any other storage devices. Nationa l Institute of Allergy and Infec tious Diseases (NIAID) shall not accept liability for any statement made that arc sender ' s own and not expressly made on behalf of the NlAlD by one of its represen tatives. -----Original Message----From: Katz , Ruth Date: Friday , January 31 , 2020 5:33 PM To: Conrad , Patric ia (NIH/NTAID} [E] Cc: Katz , Ruth Subject: Re: Tony and Conronavims --------~~ ---------- (b)(6} Hi Patty, Sorry to bother you. Just checking in to see if you have any update. We con tinue to hold the date and room. Thank s so much. Hope all is well - Ruth Sent from my iPhone On Jan 27, 2020, at 2:45 PM, Conrad, Patricia (N IH/NIAID) [E] (b) ( >> wrote: ---------------------- Hi ruth - will get back to you as soon as we can Patricia L. Conrad Public Health Ana lyst and Specia l Assistant to the Director National Institu te of Allergy and Infectiou s Di seases The Nat ional Inst itut es of Health 31 Center Drive , MSC 2520 - Room 7A03 Bethesda, Maryland 20892 (b)(6) 301-496 -4409 fax NIH-002266 Disclaimer: The informa tion in this e-mail and any of its attachments is confidential and may contain sensitive information. lt should not be used by anyone wh o is not the original intended recip ient. If you have receiv ed this e-mail in error please inform the sender and delete it from your mai lbox or any other storage devices. Nationa l Institute of Allergy and Infectious Diseases (NJATD) sha ll not accept liabi lity for any statement made that are send er\ own and not expressly made on behalf of the NIA ID by one of its represen tat ives. From: Katz , Ruth > Date: Monday , January 27, 2020 4:25 PM To: Comad , Patri cia (NIH/NIAID) [E]__________________ Cc: Katz, Ruth > Subject: Tony and Conronavirus --------------------~~= Cb _H_6) Hi Pat ty, Hope all is well and that your 2020 is off to a good, if no doubt, busy start. Conta cting you direc tly because you have always been my best "go to" person when it comes to Tony and acti vities at the Institute. Hope you can be of help again. 1would like to do a Public Health Grand Rounds session on the coronavirus here at our Aspen DC offices hopefully on February 11 (from 12 until about 1: 15pm; lunch is made avai lable to attendees). Ron Klain, former Obama Ebo la czar -- is availab le -- and hope Tony might be as we ll. Tony and Ron are my first two cho ices. Perhaps we might add someone from CDC. 1 suspect we could get some good press, especially if Tony is in the lineup . Know how terribly busy Tony is, but hope 1his might be a possibility. Any chance? As always, many thanks All best , Ruth RUTH J. KATZ Vice President, Aspen Institute Execu tive Director, Health , Medicine and Society Program The Aspen Institute ruth.katz @ aspeninstin1te.org 202-736-5827 NIH-002267 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Tue, 4 Feb 2020 00:29:06 +0000 Kai Kupferschm idt Greg Folker~ RE;coronavirus quick question --------=-:-=--------(b)(6) ;Billet, Courtney (NIH/NIAID) [E] Kai: Sorry that I got to this so late. I have been swamped. I just read your story in Science. It is unfortunate that t hey did not interview the patient. Obviously, t his changes the conclusion of the paper . My comment: "There's no doubt after reading [the NEJM] paper that asymptomatic transmission is occurring" was made because there has been a lot of discussion among Chinese investigators that asymptomatic infection is occurring in Wuhan City and Hubei Province, yet no pub licat ion came out and said this . Since this was the first publication supposedly docum ent ing this phenomenon , that is why I referred to t he paper and made my comment. It is unfortunate that this error was published , but it still does not really change anything. Rather than rely on rumors, this evening I telephoned one of my colleagues in China who is a highly respected infectious di seases scientist and health official. He said that he is convinced that there is asymptomatic infection and that some asymptomatic people are transmitting infection . The NEJM paper may be incorrect , but according to reputab le Chinese scientists, my statement is correct. Having said that , I have been saying for some time that even if asymptomatic infection occurs, it is very unlikely to be a major driver of the outbreak since most transmi ssions occur from someone who is asymptomatic. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31 , Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : Cb)(6) FAX: (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not NIH-002268 accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Kai Kupferschmidt -----------Date: Monday, February 3, 2020 11:47 AM (b)(6) ------~~ -------- To: Fauci, Anthony (NIH/NIAID) [E] Subject: coronavirus quick question CbH6J> Tony, do you have 5 minutes for a quick phone call? Wr it ing a story about the German paper claiming an asymptomatic case. Turns out the woman did have symptoms . You gave the paper a lot importance, so really wanted to get your reaction on this. Cheers Kai Kai Kupferschmidt contributing correspondent "Science" (b)(6) (b)( t wit t er: @kakape NIH-002269 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:28:34 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Coronav iru s - reporter 's questions NIA ID in qu ir ies, please. Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e -mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Rob Britt Cb)(6) Se nt: Sunday, February 2, 2020 5:10 PM To: Fauci, Anthony (NIH/NIAID) [E) Subject: Coronavirus - reporter's quest ions ------~~ -------- CbH6)> Hi Dr. Fauci: We are updat ing our coronavirus st ory per iodi cally, keeping it factual and level-headed, and I have seen your comment s o n NPR Friday and in the NV Times ove r the weekend, so I hope you could comment very briefly for our story : -- What's your expectation fo r whether thi s will become a pandemic? -- Pandemic does not necessarily equate to a terrible situat io n, comp ared to , say bad flu seasons. What 's your expectation on the pote ntial severity of t his coronavirus? -- And your suggestion to people in the U.S. who m ight be very concerned? Thanks for any help you can provide. Cheers, Rob Robert Roy Britt Top Write r on Medium in Science & Healt h. Contr ibutor to OneZero (science) & Element al (health). Former ed itor-in -chief of Live Science and Space.com. NIH-002270 (b)(6) (b)(6) NIH-002271 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:27:31 +0000 Seth Lederman Erbelding, Emily (NIH/NIAID) [E];Cassetti, Cristina (NIH/NIA ID) [E] RE: New NHP data on our vaccine for smallpox & monkeypox Seth: I am swamped with coronavirus stuf f, and so I am forwarding thi s to Emily Erbelding to tak e a look and respond. Thanks. Best regard s, Tony Anthony S. Fauci , MD Directo r National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b) (6) FAX: (301 496-4409 E-mail : (b)(6) The infor mation in this e-mail and any of its attachments is confidential and may conta in sensitive informat ion. It shou ld not be used by anyone who is not the origina l intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . (b)(6)> From: Seth Lederman Date: Friday, January 31, 2020 11:05 AM -------~~ To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: New NHP data on our vaccine for smallpox & monkeypox ------------- --------- Dear Tony, I enjoyed your corona virus presentation at ASM Biothreats, and understand why you couldn't linger. I'm writing w ith an update on our horsepox-based vaccine program. On Wednesday, we presented a poster on our further work w ith TNX-801 (horsepox) as a potent ial vaccine for smallpox and monkeypox. We found that vaccination of cynos with TNX-801 resulted in sterilizing immunity (no lesions) in 8/8 animals compared to a synthesized ACAM-like vaccinia wh ich resulted in prot ection, but lesions on 2/3 animals. More complete information is on th e poster attached, which is available on our webs ite at (https ://conten t .egu isolve.net/tonixpharma/medi a/10929ac27f4fb5f5204f5cf41d59a121 .pdf ). The press release is also attached and available on our website at (https :// ir.tonixpharma .com/press releases/ detail/118 6). NIH-002272 (b)(4) - (b) (4) We'd welcome the opportunity to discuss the data with you and your team. Best, Seth Seth Lederman , MD I Chief Executive Officer Tonix Pharmaceuticals Holding Cor p. I NASDAQ: TNXP 509 M adison Ave nu e . Suite 160 8, New Yo r k, NY 10 022 Tel____ _.hl@ --------- I Fax 212 923 5700 -'-'"""= I www .To nixPharm a.corn NIH-002273 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 22:21:41 +0000 Steinberg, Danielle Conrad, Patricia (NIH/NIAID) [E);Billet , Courtney (N IH/NIAID) [E) RE: PBS Nature inquiry about Coronavirus Danielle: Many coronaviruses exist in animal reservoirs , particularly in bats. Remember that for t he SARSoutbreak in 2002, bats infected palm civet cats who were sold in live/wet markets and the civet cats spread the virus to human . Same for MERSbats to camels to humans. You ask that there have been animal markets for a long time, and so why now. The fact is that this is likely pure chance+/- more interactions in the human-animal interface . Animal viruses mutate and most of the time the mutations have no significant impact on virus transmission to humans . Sometimes they mutate and allow single "dead end" transmissions to individual humans with no efficiency in going human to human and so we get individual infections and no outbreak as we have seen with HSNl and H7N9 influenzas that jump from chickens to humans but do not go from human to human. And then rarely, animal viruses mutate and the mutat ion allows them not only to jump species t o humans, but to also efficiently spread from human to human . That is what we saw in SARSand now we see this with 2019-nCoV, which seems to have adapted itself very well to human to human transmission, as per what is happening in China. I hope that this is helpful. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002274 From: Steinberg, Danie lle Date: Friday, January 31, 2020 2:20 PM To: Fauci, Anthony (NIH/NIAID) [E_______ ------~~ Cb) _C_ 6)> Subject: PBS Nature inquiry about Coronavirus Hi Dr. Fauci, Hari Sreenivasan of PBSNewsHour suggested I reach out to you with a specific nature questi on that we're writing about. I hope you'll be able to give us some insights - I'm sure you're extremely busy! We 'r e wo ndering about the impact of animals on the virus and specifi cally, why now? Presumably, China has been using animal markets/wildlife trade in these exact ways for a while, so what changed or is different now to cause this illness and outbreak? Any other information you can provide on how animals are involved wo uld be greatly appreciated. Thank you ! Best, Danielle Steinberg Danielle SteinbergI Digital Lead, NATUREI + 1 (212) 560-3049 (office) I l I 825 EighthAvenue 14th Fl. I New York, NY 10019-7435 pbs.orq/natureI Facebook I Twitter I lnstagram I YouTube NIH-002275 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 16:43:08 +0000 Conrad, Patricia (NIH/NIAID) [E) Barasch, Kimberly (NIH/NIAID) [C) FW: Bloomberg Radio 2/4 This is Bloomberg and so if we can do this, let us try. then say sorry no . Thanks. If it is too much of a hassle Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda, MD 20892-2520 Phone : (b) (6) FAX : (301 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . From: Jameelah D Robinson (BLOOMBERG/ NEWSROOM:) Date: Monday, February 3, 2020 11:23 AM To: Fauci, Anthony (NIH/NIAID) [E) ------~~ (b)(6) Subject: Bloomberg Radio 2/4 Hi Dr. Fauci! I Hope this email finds you well. I'm emailing to see if you can join Tom Keene, Bloomberg Suveillance Anchor/Editor-at-Large on his radio show tomorrow morning as a PHONER at 8:00am or 8:15am Et to discuss the Coronavirus. Please let me know if we can make this happen. Many thanks! -Jameelah Jameelah Robinson , M.S. Bloomberg Surveillance Television & Radio Bloomberg TV is the world's most-watched business news network, available in more than 360 million homes worldwide . Watch us live on our website, smartphones, iPad NIH-002276 app and the Bloomberg Professional Service. http://Bloombe rg .com/tv/ Bloomberg Radio can be heard live in NY (Bloomberg 1130AM) , Boston (1200AM), San Francisco (960AM) and now Washington O.C. (99.1 FM) via our local stations. You can hear us nationally on Sirus/XM Channel 119, and globally via the Radio+, I Heart, and Tune-In Radio Apps, or 24/7 at http://www .bloomberg .com/audio NIH-002277 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:17:23 +0000 Walensky, Loren D.,M.D.,Ph .D.;Glimcher, Laurie,M.D.;Auchincloss, (NIH/NIAID) [E] Subj ect: RE: Wuhan nCoV Inhibitors Hugh Loren: (b)(6) Thanks fo r t he note. Best regards, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who Is not the original Intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . ------------- From: Walensky, Loren D.,M.D .,Ph .D. Date: Sunday, Februa ry 2, 2020 11:28 PM To: Glim cher, Laurie,M .D. (b)( ; Auchincloss , Hugh (NIH/NIA ID) [E] -------- ------------ Subj ect : RE: Wuhan nCoV Inh ibitors (b)(6) -.a-s-= (b)(6J>; Fauci, Anthony (NIH/NIAID) [El ----------- (b)(6) (b) (4) NIH-002278 (b)(4) PS; Dr. Fauci, (b)(6) ------------------------ Thank you again for any guidance you can provide so that we can try to be of help. Best, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator , Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Institute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 (b)(6) Email; (b)(6) Twitter: ------ From: Glimcher, Laurie,M.D . --------------- Se nt: Sunday, February 2, 2020 9:33 PM To: Anthony (NIH/NIAID) Fauci---------,.(b)(6) (b)(6) (b.--. H=6) Hugh Jr Auchincloss Cc: Walensky, Loren D.,M .D.,Ph.D. Subject: Fwd: Wuhan nCoV Inhibitors -------------- Tony and Hugh, Loren Walensky is a superb physician -scientist at Dana-Farber (b)(6) ----------------- If this is of interest to you, please let me know or contac t him directly. Many thanks, Laurie Laurie H. Glimcher, M.D. President and CEO NIH-002279 Dana-Farber Cancer Inst itute Richard and Susan Smit h Professor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 ) §) tel. 617.632.2161 fax Begin forwarded message: From: "Walensky , Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7 :23:54 PM EST To: "Glimcher, Laurie,M .D." (b)(6)> ------------------------------ ~= (b)(6J> (b) (4) Hi Laurie . I hope all is well on your end . (b) (4) NIH-002280 (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD-PhD Program Dana-Farber Cancer Inst itute/ Harvard Medical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b) (6) Fax: 617-582-8240 Email: ------------ (b)(6) · The information in this e-ma il is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in en-or and the e-ma il contains patient informa tion , please contact the Partn ers Compliance HelpLine at http ://www. partners .org/compli anceline . If the e-mail was sent to you in error but does not contain patient info1mation, please contact the sender and properly dispose of the e-mail. NIH-002281 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Mon , 3 Feb 2020 15:12:39 +0000 Routh, Jennifer (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: ANSA news agency Please get someone to provide answers for me to send to this person. I do not have time to do it myself , Anthony s. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX : (301 496-4409 E-mail (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient . If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The Natio nal Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender 's own and not expressly made on behalf of the NIAID by one of its representatives . From: Battifoglia Enrica Date: Monday, February 3, 2020 5:37 AM To: Fauci, Anthony (NIH/NIAID) [El Subject: ANSA news agency ------~~ (b)(6) Dear Professor Fauci, I am Enrica Battifoglia of the Italian news agency AN SA, I already hav e had the ple asure to intervi ew you several times at the AIDSworld conferences. I would like to ask you some questions about Coronoravirus 2019-nCo V, to be published on the ANSA Science web page (www.a nsa.it/scienza ), the main online science news resource in Ital y with over 1.5M contacts each mon th. I am sure that your clarity and comp etence will be highly va luable to put some much-needed order among so many contrasting news and data , and wou ld be much appreciated by our reader s. NIH-002282 1) Do the current available data allow to understand the threat level of coronarivus 2019-nCo V in terms of both lethality and diffusion speed, and about the possible evolution scenarios of the disease? 2) What exactly we know about its modes of transmission, especially from people who do not yet have the symptoms? 3) Are the genetic sequences provided by China enough to start working on a vaccine? What are the technical times to develop a working vaccine in terms of scientific research, and what are the approx times for the necessary legal certifications, and for industrial production and distribution? 4) 2019-nCov is the third Coronavirus aggressive for humans that has appeared in the East in the last 20 years and in 2009 the virus responsible for the flu pandemic too did come from China: what sort of preventive measures could be practicable to reduce the risk ofrepetition of these events? Thank you so much for your time your attention! Kindest Regards Enrica Battifoglia Science and Technology Head Editor ANSA News Agency II contenuto di questa e-mail e rivolto unicamente a/le persone a/le quali e indirizzato; le relative informazioni sono do considerarsi strettamente riservate e tutelate ai sensi de/ Regolamento UE 2016/679 (GDPR) per la Protezione dei Doti Personali, nonche de/ D. lgs. n. 196/2003 e successive modifiche. Sono vietati la riproduzione, la diffusione e /'uso di questa email in mancanza di autarizzazione def destinatario. In caso di ricezione de/la presente e-mail per errore, si prega di non NIH-002283 diffonderla, di informare immediatamente ii mittente e di eliminarne ogni copia. Le opinioni espresse in questa e-mail appartengono esc/usivamente al mittente e potrebbero non riflettere necessariamente que/le dell'Agenzia ANSA. The content of this e-mail is only addressed to the people to whom it is addressed; the relevant information has to be considered as confidential and protected under the Regulation EU2016/679 (GDPR),General Data Protection Regulation, as well as the Legislative Decree 196/2003 and subsequent amendments. The reproduction, distribution and use of this e-mail in the absence of the recipient's authorization is forbidden. If you receive this e-mail by mistake, please do not disseminate it, inform the sender immediately and delete any copies. The opinions expressed in this message belong to sender alone and may not necessarily reflect those of ANSA AGENCY. NIH-002284 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon , 3 Feb 2020 15:10:32 +0000 Joe Palca RE: Coronavirus vaccine Joe: Thanks for the note. The has nothing to do with t he validity of the test. We see this w ith other viruses when you look at shedding. When there is a low titer of virus, any specific site (in this case a nose or throat swab) may vary between positive and negative even though the person is clearly still infected . It could be that the virus is there in the throat at one point and cleared at another and comes back again. Alternatively, it may be that the virus is always there, but at different titers and at some points it is pre sent below the sensitivity of the test, even though the test is in general quite sensitive. Hope t hat this is helpful. Best regard s, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 Nation al Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail (b) (6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the or iginal intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its represent atives . From: Joe Palca Date: Monday, February 3, 2020 9:30 AM -----~~ To: Fauci, Anth ony (NIH/NIAID) [E) Subject: FW: Coronav irus vaccine ------- (b)( From: Joe Palea Date: Monday, February 3, 2020 9:13 AM NIH-002285 > To: 'anthony.facui@nih.gov ' Cc: 'Deatrick, Elizabeth (NIH/:-:N'."." IA -:-: 1-:0-:) :-: [C'.":". ] ,~====-----= (b)(6)> (b"'"" )~ ( >; Scott Hensley (b)(6) Subject: RE: Coronavirus vaccine Hi Tony, It's been nice hearing you on the various press conferences ...can't believe we're still both doing this. Have a question about something Redfield said in Friday in the White House briefing about nCoV. He said using their PCRassay, the virus can be detectable one day, then not the next, then detectab le. I'm curious about this . I see a few possibilities: 1. The test isn't as sensitive as CDC hopes 2. The sample was taken from different places 3. With low viral ti ter, it may seem like the virus "disappears" from one day to the next. 4. The virus may be hanging out in the terminal bronchioles, and only pop up t o t he upper respiratory system from time to time. Arn I on the right track? Wou ld you have a few minutes today to record an interview with me? Joe NIH-002286 From: (b)(6) Date: Mon, 3 Feb 2020 05:45:35 -0500 Conrad, Patricia (NIH/NIAID) [E) Fw d: Interview request (Seoul, Korea) To: Subject: Sent from my iPhone Beg in forwa rded message: From: ;;'< } ~ '-t (b)(6) > Dat e: February 3, 2020 at 2:29:21 AM EST To: "Fauci, A nthony (NIH/N JAID) [E]' Subject: Interview request (Seoul, Korea) -------'=""'""'= --------(bH6l > Dear Or. Fauc i. I am Mrs. Hyun-Na Cha of TBS, metropolitan radio statio n of Seoul. South Korea. I am the directo r of currun t- issue radio show of TBS and I'd like to have a telephone interview with you on my radio program about co ronavirus issue all over the wor ld. As Korea is a very close count·y to China and many people are very concerned about this issue. I wou ld like to hear your op inion as a world authority on this issue. The time fo r phone interview would be about 6 a.m . at Maryland time and I want to proceed it through an English-Korean interp rete r. I wou ld apprec iate it if you could reply to me if you are poss ible . The host of my prog ram is a political expert who is a Ph.D. from MIT, Or.Kim. Respec tf ully, Mrs. Hyun- na Cha (b)(6) TBS. Seoul. Korea NIH-002287 From: Fauci, Anthony (NIH/NIAID) [E) Mon, 3 Feb 2020 03:47:33 +0000 Howard Schatz RE: If too busy then pass---l'd understand Date: To: Subject: Too soon to predict. It probably will evolve into a widespread infection (pandemic) with lower mortality than we are now seeing (2%). More similar to 2009 HlNl flu than SARS even though the virns (coronavirus) is in the same family of viruses as SARS. -----Original Message----From: Howard Schatz ----------- Date: Friday , January 31, 2020 8:51 AM To: Fauci . Anthony (NIH/NIAID) [E] -----Subject: If too busy then pass---T'dunderstand (b ~)~(= = CH= sb--., 6) Tony, New Coronavirus: saw you on national news with a dozen others at DT's table yesterday. Seems like this new one though serious and very contagious is not as lethal (40: I ?) as SARS, others. What is your cunent thinking on it? Hope all is well, otherwi se. Thanks , howard NIH-002288 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 03:45:59 +0000 Auchincloss, Hugh (NIH/NIAID) [E] FW: Wuhan nCoV Inhibitors (b)( 4 Please handle this . T hanks . From: Glimcher, Laurie,M .D. Date: Sunday, February 2, 2020 9:33 PM To: Fauci, Anthony {NIH/NIAID) [ E] ------ (b)( -------------(b = )c-c (= >; > Auchinclo ss, Hugh (NIH/N IAID) [ E] (b)( Cc: Walensky , Loren D.,M .D.,Ph.D. --------------Subject: Fwd: Wuhan nCoV Inhibitors Tony and Hugh, Loren Walensky is a superb physician-scientist at Dana-Farber (b)(6) ----------------- If th is is of interest to you, please let me know or contact him directly . Many thanks, Laurie Laur ie H. Glimcher , M.D. President and CEO Dana -Farber Cancer Institute Richard and Susan Smi t h Profes sor of Medicine Harvard Medical School 450 Brookline Avenue, Dana 1628 Boston, MA 02215 "--~~ @.!.!te l. 617.632.2161 fax Begin forwarded message: From: "Wa lensky, Loren D.,M .D.,Ph.D." Subject: Wuhan nCoV Inhibitors Date: January 30, 2020 at 7:23:54 PM EST To: "Glimcher, Laurie,M.D." (b)(6)> ------------------------r;a-.-,--.= --------------NIH-002289 (b)(6) Hi Laurie. I hope all is we ll on your end . (b) (4) (b) (4) Thanks so much, Loren Loren D. Walensky, M.D., Ph.D. Professor of Pediatrics Principal Investigator, Linde Program in Cancer Chemical Biology Attending Physician in Pediatric Oncology Director, Harvard/MIT MD -PhD Program Dana-Farber Cancer Institute/ Harvard Med ical School 450 Brookline Avenue, LC3216 Boston, MA 02215 Office: (b)(6) Fax: 617-582-8240 (b)(6) Email NIH-002290 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-ma il was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www .partners .org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. NIH-002291 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Mon, 3 Feb 2020 02:10:49 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Homozygous for Alpha-1 antitrypsin and coronavirus? Please handle. (b)(6)> From: Ulrica Molstad Date: Sunday, February 2, 2020 9 :07 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6)> _.:__:,__ _:...;:,_.:J===~=---Cc: Ulrica Molstad _________ Cb _)_C6) _> Subject: Homozygous for Alpha-1 antitrypsin and coronavirus? ----------------~~ H·1 I. I read that you are an expert working for NIAID and that you got interviewed about treatments for the corona viru s. I am a Swedish physician specialized in clinical chemistry. (b)(6) and wanted to share a hypothesis I have. I believe that some patients who are seriously ill in corona virus {or flue/SARS) with lung symptoms have a lack of normal/well functioning Alpha-1-antitrypsin for example PiZZ. Alpha1 anti trypsin is an acute phase reactan t and increases in sick people. I have seen that the Alpha-1antitrypsin level can be elevated in a severely ill person (HlNl) if measured in a laboratory, even t hought the patient was homozygous for mutations in the Alpha-1-a ntit rypsin gene. An elevated level of Alpha-1 antitrypsin is misleading and can result in the physician believing t hat there is nothing wrong with the patients function of Alpha-1-antitrypsin. I also guess that critically ill ECMO-treated patients with lung symptoms migh t benefit from receiving Alpha-1 anti protease inhibitor in addition to other medicatio ns given to them. What do you think? I believe that this information can contribute in understanding why some supposedly healthy individuals gets really sick and even die in corona virus, flue/HlNl or SARS. (b)(4 I wou ld appreciate if you replied shortly to me so that I know that my e-mail has been read . Best regards, Ulrica Molstad, M .D. NIH-002292 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Mon, 3 Feb 2020 00:50:43 +0000 James Krellenstein RE: 2019-nCoV Testing for Public Health Labs James: Thanks for the heads-up. I will see what I can do. Best, Tony ---------- From: James Krellenstein Date: Sunday, February 2, 2020 7:37 PM (b)(6) --------. ~ To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) >; Lord, Aaron Cc: David Barr ------====~~----(b)( 6) ------------- (b)(6)Peter Staley Subject: 2019-nCoV Testing for Public Health Labs Tony: I hope this emai l finds you well. Over the past 48 hours, PrEP4AII has received multiple requests from leaders of public health departments and public health practitioners to begin publicly pressuring CDC/HHS to ensure that properly equipped publ ic health labs (besides CDC's lab in Atlanta) can perform real time reverse transcription PCR(qRT-PCR)testing for 2019 Novel-Coronavirus (2019-nCoV). Our understanding is that given the public health emergency decla red by HHS, an emergency use authorization (EUA) from the FDA is required for public health labs to perform their own lab developed test for 2019-nCoV, even if it is using the CDC's published qRT-PCRprotocol and primer/probe sequences ( htt ps:/ /www .cdc .gov/ coronav i rus/2 019-ncov /down loads/ rt -pcr-pane l-fo r- detect ion- i nstr uctions . pdf ) , and the lab is capab le of handling BSL3+samples. We understand the extreme delicateness of this situa t ion, and also that it is outside of our normal wheelhouse . But given the concerns of our colleagues in the public health sector, we thought it was important to give you a heads up regarding this request . Let us know if there is anyway we can help . Sincerely, James Krellenstein Data, Science and Policy Committee The PrEP4AII Collaboration 109 S 5th St, Brooklyn, NY 11249 (b)(6) NIH-002293 James B. Krellenstein he - him - his (b)(6) (Sent from a mobile device) NIH-002294 From: Date: To: Subject: coronavirus Attachments: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 23:54:27 +0000 NIAIDODAM FW: Invitation for an expert panel webinar on the role of micronutrients and 2020.02.02 Expert panel objectives.docx Let us discuss. Probably no. From: --------------------- (b)(6)> Date: Sunday, February 2, 2020 9:49 AM To: Fauci, Anthony (N IH/NIAID) [E] Cc: Peter van-Dael .,,;.__.;. __ ------,;-. = .;...;;...;,_.=== (b)(6)1> (b c:" ):=('=' 6);---- Subject: Invitation for an expert panel webinar on the role of micronutrients and coronavirus Dear Dr. Fanci, I wou ld like to address you for an expert panel webinar on the role of micronutrients and corona virus Du e to the new coronavirus outbreak and the rapidly escalating global spread, lots of questions are raised regarding the role of micronutrients in support ing the immune system. DSM has reached out to me with a request to organize rapidly a focused expert panel in order to estab lish expert guida nce summa rizing key points with respect to the role of micronutrients in supp orting our body 's immun e response, in light of the current genera l consciousness that among other factors nutrition is important in combatting infectious diseases. Peter Van Dael, head of Nutrition Science & Advocacy, is responsible for the coordination of this activity at DSM . I agreed to take on this challenge and therefore intend to organize this expert panel through webinar in order to manage the challenges related to busy agendas and travel within the next week , if possible. The webinar is expe cted to last for about 3 hours maxinmm and would be facilitate through the distribution of a short background document I will share in order to facilitate the discussion. J will try to reach out to you tomorrow by phone in order to rev iew whethe r you would be available for this engagemen t and whe ther you would you have potentia l questions prior to agree ing to participate. With our best regards, Peter Manfred NIH-002295 Dr. Manfred Eggersdorfer Professor for Healt hy Age ing Dr. Peter Van Dael DSM Nutr ition Science & Advocacy (b)(6) (b)(6) NIH-002296 From: (b)(6) Date: Sun, 2 Feb 2020 18:20:17 -0500 Carlos del Rio Re: [External] RE:Mexican researchers have defined the structure of the Corona To: Subject: virus Very inte resting. On Feb 2, 2020, at 9:07 AM, Del Rio, Carlos ---------- (bH6)>wrote: sent me this update. Thought you would enjoy. --------Interesting to see how they view outbreaks ..... (b)(6) Coronavirus new s over the weekend was a sma ll net positive (although there were plenty of nega tives). Encouragingly, doctors appear to be having some success treating patients with existing antiviral drugs - GILD's remdesivir improved the clinica l con dit ions of a coronavirus patien t in Washington state (WSJ) while Thailand said it had achieved good resu lts using antiviral drugs originally designed for the flu and HIV (Bloomberg). It's way too early to tell whether these drugs will perfom1 well in othe r patients (and a vaccine is still some time away) , but the progress noted in the US and Thail and is positive. The PBOC said it would inject CNY 1.2T worth of liquidity on Monday 2/3 to ensure markets operate smooth ly when they reopen from the New Year holiday (this works out to about CNY150B of net incremental liquidity given CNY1.05 T of reverse reports are set to mature on Monday). The gov' t also announced other steps (including waiving equity ownership limits for some insurers) aimed to bolstering market confidence . The global corona viru s case count cont inues to rise (it now stands at ~ 15K as of Sunday morning withe death toll north of 300) whi le more travel restrictions are being impo sed by governments and companies around the world (Apple said it would shutte r all its stores and offices in China until Feb 9). According to a CNBC update , areas of China responsible for ~8 0% of GDP and ~90% of exports are set to stay closed until at least Feb 10. Carlos del Rio, MD. Sent from my iPhone On Feb 1, 2020, at 11: 13 PM , Fauci , Anthony (N IH/NIAID) [E] (b) (6)>wrote: -------- I love it! □□ NIH-002297 -----Original Message----------~~ From: Del Rio, Carlos 4 Cb>< ~> Date: Friday, January 31, 2020 10:05 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6) Subject: Mexican researchers have defined the structure of the Corona virus ------ --=-= This e-mail message (including any attachments) is for the sole use of the intended recipient(s) and may contain confidential and privileged information. If the reader of this message is not the intended recipient , you are hereby notified that any dissemination, distribution or copying of this message (including any attachments) is strictly prohibited. If you have received this message in error, please contact the sender by reply e-mail message and destroy all copies of the original message (including attachments). NIH-002298 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:56:05 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: coronavirus ------- (b)( > ------~~ From: Dr.h.c. Richard Hajdu Date: Sunday, February 2, 2020 2:00 PM To: Fauci, Anthony {NIH/ NIAID) [E] Subje ct: coronavirus -------- (b)(6) Dear Anthony Fauci. I speak hard English so I write to you using google trans lator . I have a cured corona virus cure . I am will ing to provide you . In laboratory conditions you can t ry. This medicine can destroy the virus within 12 hours . If you are interested, it is necessary to provide a way to deliver the rned ici ne to you. J live in the Czech Republic. In the city of Brno . Dr. Richard Hajdu NIH-002299 Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 22:43:15 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: coronavirus - easy, safe, and likely highly effective treatment. Attac hmen ts: Corona Virus Solution b.docx, MedGasRes_2019_9_ 4_232_273962.pdf, published article on ozone and ebola 3578-10714-4-PB.pdf From: Date: Please handle. From: Robert Jay Rowen (b)( Date: Sunday, February 2, 2020 4:24 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ > -------- ~~ (b)(6)> Subject: coronavirus - easy, safe, and likely highly effective trea t ment. Dear Dr. Fauci, I am a mere clinician . But I have published repeatedly on a therapy which, I believe, will remedy patients with coronavirus and spare a possible catastrophe, if the virus is as lethal as it appears. The therapy is ozone . It can be performed, depending on the method, for mere pennies in mater ials. It is not patentable, so, it lacks profitability needed for some payback for t he basic research to get it "approved" . It attacks a key vulnerabi lity on this virus and even Ebola. We got to 5 Ebola cases in Sierra Leone. All 5 recovered almost immed iately. No sequela. No one has repo rted anyth ing like that. I have used ozone therapy for 33 years, ;longer than anyone in North America . It absolutely changed my practice. I write essentially no prescriptions for antib iotics, including for Lyme disease. This therapy, I recent ly published, might be the solution the world desperately needs for the emerging crisis in resistant infections. I am attaching 2 papers I recently published on ozone therapy, And a manuscript we just got done to address corona virus, wh ich I am try ing to get published. It is not easy. The medical world is vested in Pharmaceuticals. I urge you to please look at this. Not patentable, it will never be a darling of industry. But just for that reason (dirt cheap), it could be a savior for thousands or more who might die from a pandemic. I am coming to you abo ut t his as one physicist came to President Roosevelt about harnessing the power of the atom at the dawn of world war 2. I do hope you will take note of what I am forwarding to you . The first file is a word document I am seeking to get published. Usually, an author will hold up on making material like this public until he get published. However, wi th lives immediately on the line, we want to alert people that the does exist an available very inexpensive and extremely safe medical treatment for this and other infections . If you have questions, please contact me here. Sincerely, NIH-002300 Robert Ja Rowen , MD (b)(6) www.D rRowenDrSu .com http://www .youtube.com/user/Robe rtRowenMD https://www .faceboo k.com/D rRobertJRowen "The doctor of the future will no longer treat the human frame with drugs , but rather w ill cure and prevent disease with nutrition" , Thomas Edison HIPAA Notification : This electronic message (includ ing any attachments) is intended only for the exclusive use of the individual to whom it is addressed. This emai l, including any attachments , is confidential and is legally privileged. If you have received it in error please advise the sender immediately by return email and then delete it from your system. The unauthorized use, distribution, copying or alterations of this email is strictly forbidden. If you need assistance please contac (b)(6) Note to Patients : There are inherent confidentiality risks in communicating by email. While safeguards are in place to ensure your privacy , you should not use email communication if you are concerned about any breaches of privacy that might inadvertently occur. NIH-002301 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:40:07 +0000 Greg Folkers (b)(6)) Conrad, Patricia (NIH/NIAID) [El FW: Getty images from coronavirus presser etc http://bit.ly/2GJ3u5F See below the link that CbH6>sent me. It is a picture of me briefing President Reagan at the NIH in 1988 . Please insert it into our flickr file with the legend that I just gave . Thanks. From: (b)(6) {NIH/CC/BEP)[El (b)(6) Date: Sunday, February 2, 2020 5:11 PM To: Fauci, Anthony {NIH/NIAID) [E] (b)(6) Subject: RE:Getty images from coronavirus presser etc http:/ /bit.ly/2GJ3uSF ------ ..---.-.-= The oldest one in the batch: https://www.gettyimages .com/detai l/news-photo/dr -anthony -fauci -lectur ing-to -pres-ronald -w-reagana nd-news-photo/50454084 ?adppopup=true From: Fauci, Anthony (NIH/N IAID) [El CbH > Date: Saturday, February 1, 2020 10:09 PM -----~~ To: (b)(6) {NIH/CC/BEP) [El (b)(6) Subject: FW: Getty images from coronavirus presser etc http ://b it .ly/2GJ3u5F fyi --------- (b)(6) From: Folkers, Greg {NIH/ NIAID) [El Date: Saturday, February 1, 2020 9:02 PM To: NIAID OD AM Subject: Getty images from coronavirus presser etc http://bit .ly/2GJ3u5F NIH-002302 Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does uot necessarily represent my views nor those of NIAJD , NIH , HHS , or the U.S. government. NIH-002303 Fauci, Anthony (NIH/NIAIO) [El Sun, 2 Feb 2020 22:36:41 +0000 To: Routh, Jennifer (NIH/NIAID) [E] Cc: Billet, Courtney (NIH/NIAID) [E];Stover, Kathy (NIH/NIAID) [E];Folkers, Greg (NIH/NIAID) [E];Conrad, Patricia (NIH/NIAID) [E];Marston, Hilary (NIH/NIAID) [E] Subject: RE: Fauci/Redfield op-ed for review Attachment s: Redfield-Fauci Joint Op-Ed V2 020120_EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h additional Fauci tracked changes still showing.docx , Redfield-Fauci Joint Op-Ed V2 020120 _EOC Cleared Revised wR3 2.2.20 JR HM GF - wit h Fauci changes added -clean copy.docx From: Date: I have gone over the document and have made a numbe r of t racked changes. In addition, for ease of reading I have accepted all the tracked changes and am sending a clean copy. Hence there are 2 attachments : 1) one w ith al l tracked changes; 2) a clean copy accepting all changes. Please note that the CDC has not announced the 3 additional cases and so depending on when this goes out we need to make sure that the offic ial number is 11 and not st ill 8Thanks ! From: Routh, Jennifer (NIH/N IAID) [E] CbH Se nt : Sunday, February 2, 2020 4 :36 PM To: Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Billet, Courtney {NIH/N IAID) [El CbH6)>;Stover, Kathy (NIH/NIAID) [El (b)(6)>; Folkers, Greg {NIH/NIAID) [El CbH6)>;Conrad, Patricia (NIH/NIAID) [El (b)(6); Marston, Hilary (NIH/NIAID) [El (b)(6)> Subject: Fauci/Redfie ld op-ed for review ------~~ Dr. Fauci Attached is the draft op-ed for you r review. Greg, Hilary and I have added proposed edits in track changes. We will send back to CDC/HHSone document with all NIAID edits in track changes. HHSwould like to get a draft to the White House at some point this evening. Thanks, Jen Jennifer Routh [E] News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda, MD 20892 Direct (b) (6) Disc laimer: The information in this e-mai l and any of its attachments is confident ial and may conta in sensitive informat ion. It should not be used by anyone who is not the original intende d recipient. If you have received th is e-mail in error please inform the sender and delete it from your mail box or any other storage devices . The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender's own and not express ly made on behalf of the NIAID by one of its representat ives. N IH-002304 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 19:24:26 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Specific Questions About CoronaVirus Please handle. From: Rafael C. R. (b) (6)> Date: Sunday, February 2, 2020 12:34 AM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Specific Questions About CoronaVirus --------------- .----..-.= (b)(6) Hi Or. Fauci, you might not remember me from my previous email. I'm a Brazilian who asked you some months ago about the influenza virus differences across regions. I recently t raveled to DC and NY and had a great time there (before the Corona Virus outbreak) I have some specific questions about the new Corona Virus, and would be very grateful if you can answer them : 1- Using availab le data, I've made a simple spreadsheet attempting to pred ict the virus behavior : https://do cs.google .com/spre adsheets/d/1DAHQt FzXOFKU405k8p864JBVHAlfzsHQghuywaTNbE/ed it#gid=O I've used exponent ial tr end, although it seems to be spreading slower than the expected, I'd like to know if there's an accurate model for pred icting th is virus. Also, I assume virus don't always spread exponentially? 2- I listened to your interview podcast https ://edhub .ama-assn.org/j n-learning/aud io-player/18197306 . Really amazing content. Let's assume this is going to be a wor ldwide outbreak. How can I get prepared for the worst? Buy water, dry food , stay indoors, w ithdraw money, etc? Once again, I'd like to thank you very much for reading this emai l. I bet t his is a very busy time for you, so it means a lot to me Thank you, Rafael NIH-002305 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAI0) [E) Sun, 2 Feb 202018:33:43 +0000 Liang, Jake (NIH/NIDDK) [E) Mark Dybul;Conrad, Patricia (NIH/NIAID) [E);Barasch,Kimberly (NIH/NIAID) [C] RE:Favor Thank s, Jake. Mark will contact you directly . From: Liang, Jake (NIH/NIDDK) [E]________ Cb _>_C6b Date: Sunday, February 2, 2020 1:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Cc: Mark Dybul ___ ......;._-===~~-----:-----:-----:----:--~ (b)(6); Conrad, Patricia (NIH/NIAID) [E) (b)(6); Barasch, Kimberly (NIH/NIAID) [CJ Subject: Re: Favor ------~~ --------- (b)(6) Hi, Tony, I just returned from an overseas trip but should be around tomorrow and can certainly clear some time to meet with Mark. I met Mark at the NAM meeting last year and would love to hear what they have to say. Let me know what works. Good luck in dealing with the new coronavirus pandemic (not sure whether it is qualified as one yet; if not, pretty close)!! Jake From: Anthony Fauci (b)(6) Date: Sunday, February 2, 2020 at 12:20 PM To: Jake Liang CbH6>> Cc: Mark Dybul CbH6>>,"Conrad, Patricia (NIH/NIAID) [E)" CbH6>, "Barasch, Kimberly (NIH/NIAID) (C)" CbH6>> Subject: Favor ----------- Jake : Sorry for this last minute ask, but Cb)( , Ambassador Mark Dybul, who is the former Head of PEPFARand the former Director of the Global Fund to Fight AIDS, TB, and Malaria will be at the NIH tomorrow with a scientist who has some very interesting data on hepatitis B. I was supposed to meet with them, but I am swamped with the coronavirus. Is there any chance that you can meet with them briefly tomorrow. I believe that you might be interested in seeing them. I have copied Mark on this e-mail and so I will ask him to e-mail you to see if you can make this happen. Many thanks. Best regards, Tony Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 NIH-002306 Phone : (b) (6) FAX : (301) 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the origina l intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infect ious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002307 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 18:02:22 +0000 Billet, Courtney (NIH/NIAID) [E] RE: Seeking comment on Indian paper about new Coronavirus From: Date: To: Subject: Geeeez --------- From: Billet, Courtney (NIH/NIAID) [E] Se nt: Sunday, February 2, 2020 12:53 PM To: Fauci, Anthony (NIH/NIAID) [E] ------ (b)(6) -= (b-c)(c-= 6) Cc: M arston , Hilary (NIH/N IAID) [E] ·; Folkers, Greg (NIH/NIAID) [E] (b) (6)>; Stover, Kathy (b)(6J>; Conrad, Patricia (NIH/NIAID) [E] (b) ( ·> (NIH/NIAID) [E] (b)(6J>; Routh, Jennifer (NIH/N IAID) [E] Subject: Fwd: Seeking comment on Indian paper about new Coronavirus -------- --------- FYI re the paper from the Indian researchers . Talk about trying to put the genie back in the bot tle! Yeesh. (b)(6) From: " M ascola, John (NIH/VRC) [E]" Date: Sunday, February 2, 2020 at 10:39:42 AM To: "Routh, Jennifer (NIH/NIAID) [E]" (b)( >, "Graham, Barney (NIH/VRC) [E]" (b)(6) "Hiatt, Nis... sa -:-:(N".':'. IH :-:/-::V-:: R~C':"" ) :-:: [C~]":":==::::::...;___ _,_,(b);.,~=6)> ------- ~= ---------Cc: "Ma rston , Hilary (NIH/NIAID ) [E)" (b)(6)>, "Billet, Courtney (NIH/NIA ID) [E]" >, "Stover, Kathy (NIH/NIAID) [E]" (b)(6)> Subject: RE: Seeking comment on Indian paper about new Coronaviru s -------- (b)( Also note the following from the author on the BioRxiv comment sect ion: PrashantPradhan 8 hours ago This is a preliminary study . Cons idering the grave situati on, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provide d by scient ific co lleagues at BioRxiv forum and elsewhe re, the story has been differently interprete d and shared by social med ia and news platforms . We have positively receive d all criticisms and comments . To avoid further misinterpretati on and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version afte r reanalysis, addressing the comments and concerns . Thank you to all who contributed in this open-review process . : Authors of the Manuscript NIH-002308 _________ .. From: Routh, Jennifer (NIH/NIAID) [El Date: Sunday, February 2, 2020 10:35 AM To: Graham, Barney (NIH/YRC) [El ________ (b)(6) --------~= Cb _H_6); Hiatt, Nissa (NIH/VRC) (CJ (b)(6) Cc: Marston , Hilary (NIH/NIAID) [El CbH ; Mascola, John (NIH/VRC) [El CbH6)>; Billet, Courtney (NIH/NIAID) [El CbH6)>; Stover, Kath y (NIH/NIAID) [E) (b)(6) Subject: RE: Seeking comment on Indian paper about new Coronavirus Hi Barney We consulted with HHS and ASF. OCGRis going to send a note to the reporter to decline, noting that the paper is not peer-reviewed. Please let us know if you receive similar requests. Thanks, Jen Jennifer Routh [El News and Science Writing Branch Office of Communications and Government Relations National Institute of Allergy and Infectious Diseases (NIAID) NIH/HHS 31 Center Drive Room 7A17C Bethesda , MD 20892 Direct: Cb)~ Disclai mer: The informatio n in this e-mai l and any of its attachments is confident ial and may contain sensitive information . It should not be used by anyone who is not the original intende d recipient. If you have rece ived this e-mail in error please inform the se nder and delete it from your mailbox or any other storage dev ices. The National Institute of Allergy and Infectious Diseases shall not accept liability for any statements made that are sender"s own and not express ly made on behalf of the NIAID by one of its representa tives. ----------- From: Graham, Barney (NIH/YRC) [El Date: Saturday, February 1, 2020 2:11 PM To: Hiatt, Nissa (NIH/VRC) (CJ (b)( 6) > -------- Cc: Marston , Hilary (NIH/NIAID) [El _______ (b)( (b)( ; Routh, Jennifer (NIH/NIAID) [El Cb _>_<6J _ >; Mascola, John (NIH/YRC) [El (b)(6) Subject: FW: Seeking comment on Indian paper about new Coronavirus Hi Nissa and Jen, This is one we don't want to answer without high-level input, but wanted you to know about the rising controversy . BG NIH-002309 From: lssam AHMED Date: Friday, January 31, 2020 5:27 PM To: Graham, Barney (NIH/YRC) [E]________ -------- ~= Cb _H_6) Subject: Seeking comment on Indian paper about new Coronavirus Dear Dr Graham, I'm a science journalist with news agency Agence France-Presse wr iting with a request -- apologies for reaching out on a Friday evening! I was to ld by a contact you may be willing to give an opinion on this paper that has just gone live https:ljwww .biorxiv.org/content/10 .1101/2020.01.30.927871v1.fu ll.pdf it suggests the new Coronavirus has four inserts similar to HIV-1 and this is not a coincidence. Thanks you very much, if you are able. lssam Ahmed lssam AHMED Health, Science and Environment Correspondent 1500 K St. NW - 20005 Washington Tel : (202) 414-0521 June 24 , 2020 Virusdeathtoll nears half a million ascasessurge in US, Latin America Join us on: I) Clafp.com NIH-002310 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 17:13:03 +0000 Mark Dybul RE:A connection to jake Mark: Thanks for the note. Sony that l had to cancel. This is Wbite House i11full overdrive and I am in the middle of it. Reminiscent of post -anthrax days. I will send an email to Jake toda y to introduce you. Again , sorry about the cancellation. Hope to see you soon. Regards to Jason. Best , Tony -----Original Messa... g""e-------------~~ From: Mark Dybul (b) (6) > Date: Sunday, February2, 2020 11:37 AM To: Fauci, Anthony (NIH/NIAID)[E] Subject: A connection to jake (b)(6) Hey tony Know you are buried in coronavirus. Totally understand need to cancel meeting tomorrow. We will set up a zoom in hen things calm down. We have made additiona l progres s on hbv including data from 2 new mouse models. We were going to share Monday Realize this is last minute but mig ht it be possible for you to connect me to jak e Jiang in case we can squeeze in a meeting with him (serhat is already on east coast - we took a risk knowing you might have to cancel)? Jfyou are not comfortablewith that 1 could send him a cold caUemail mentioningwe have shared the data with you. You were kind enough to introduce us at the nam dinner when (b) (6). Hope you at least have time to enjoy Super Bowl. Hang in there - am sure everyone is leaning heavily on you as usual. Thanks much Mark Sent from my iPhone NIH-0023 13 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 16:49:35 +0000 Collins, Francis (NIH/OD) [E] Tabak, Lawrence (NIH/OD) [E] FW: Teleconference Francis: Do you have a minute for a quick call? Tony From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 11:28 AM To: Fauci, Anthony (NIH/NIAID) [E] -------= (b)( . (b=)(= ; Collins, Francis (NIH/OD) [E] Cc: Tabak, Lawrence (NIH/OD) [E) Subject: Re: Teleconference --------- (b) (6)> Tedros and Bernhard have apparently gone into conclave ....they need to decide today in my view. If they do prevaricate, I would appreciate a call with you later tonight or tomorrow to think how we might take forward . Meanwhile .... https ://www .zerohe dge.com/geopo lit ical/coronav irus-contains-hiv -insertions-stok ing-fears-over a rt ificia lly-created-b iowea pon From: "Fauci, Anthony (NIH/ NIAID) [E]" Date: Sunday, 2 February 2020 at 15:30 To: Jeremy Farrar Cc: "Tabak, Lawrence (NIH/OD) [E]" CbH6)> CbH6J>,Francis Collins (b) (6)> (b)(6) Subje ct: RE: Teleconference Jeremy: Sorry that I took so long to weigh in on your e-mails with Francis and me. I was on (b)(5) conference calls. Cb)(5l Best regards, Tony From: Jeremy Farrar Date: Sunday, February 2, 2020 7:13 AM (b)(6)> NIH-0023 14 To: Collins, Francis (NIH/OD) [E] Cc: Fauci, Anthony (NIH/NIAID) [.':: E-:. ] =====~ (b)(6)> (b'""' )( =, > ; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference ....Really apprec iate us thinking through the options ... ---------------- From: Francis Collins (b)(6)> Date: Sunday, 2 February 2020 at 12:03 To: Jeremy Farrar CbH6)> Cc: "Fauci, Anthony (NIH/N IAID ) [E]" (b)(6) --------- (b)(6), (b)(5 "Tabak, Lawrence (NIH/OD) [E]" Subject: RE:Teleconference Hi Jeremy, Thanks for forwarding these additional reflections from Mike and Bob. (b)(5) ~ (b) (5) Francis From: Jeremy Farrar (b)(6) Date: Sunday, February 2, 2020 6:53 AM To: Collins, Francis (NIH/OD) [E] ------Cc: Fauci, Anthony (NIH/NIAID) [E] ~= c6J (b... (b)(6J>; Tabak, Lawrence (NIH/OD) [E] (b)(6) Subject: Re: Teleconference Thank you See thoughts overnight from others. (b) (5) NIH-002315 Jeremy (b)(5) NIH-002316 From: Francis Collins CbH6)> Date: Sunday, 2 February 2020 at 10:27 (b)(6) To: Jeremy Farrar "'""'"".---:---:-:--:-::~===-----=-,,"=' Cc: "Fauci, Anthony (NIH/N IA ID) [E]" CbH6), "Tabak, Lawrence (NIH/OD) (b)(6) --------- [E]" Subject: RE:Teleconference Jeremy, (b) (5) I'm avai lable any time today except 3:15 - 5:45 pm EST (on a plane) for a call to Tedros . Let me know if I can help get through his thicket of protectors. Francis From: Jeremy Farrar (b)(6) Se nt : Sunday, February 2, 2020 4 :48 AM To: Andrew Rambaut (b)( > Cc: R.A.M. Fouchier (b)(6); Fauci, Ant hony (NIH/NIAID) [E) (b)( Patrick Vallance (b)(6); Drosten, Christian ==========-~=(b)(6)> ; M.P.G. Koopmans (b)(6) ; Eddie Holmes (b)(6); Kristian G. Andersen (b)( ":"-""'."":'-:--:--:==============~-=-c---=Paul Schreier (b)(6); Ferguson, Mike (b)(6); Collins, Francis (NIH/OD) [El (b)(6)>; Tabak, Lawrence ~".""'.'"':"~~:-::======::!.:.... ..,,.._..,= (NIH/OD) [E) (b)( >; Josie Golding (b)(6) Subject: Re: Teleconference This is a very complex issue. lwill: (b) (5) NIH-0023 17 (b)(5) I suggest we don't get into a further scientific discussion here, but wait for that group to be establis hed. Jeremy From: ' Cb> (6) Date: Sunday, 2 February 2020 at 09 :38 To: Jeremy Farrar CbH6)J> Cc: f CbH6) [>, "Fauci, Anthony (NIH/ NIAID) [E]" CbH6)>,"Drosten, CbH ~, Patrick Vall ance ( Christian" I---=========~----_;_ CbH~,Marion Koopmans CbH6)J, __ ..!::::=="='=:,0::-_____ _ Edward Holmes r CbH6)j CbH ~ , "Kristian G. Andersen" I (b)(6) J, Paul Schreier CbH ~ M ichae l FMedSci ==========::=:~-------:::=======-==:,:,,:;-->, Francis Coll ins( Cb)( ~ (b)( ~ ~=========,,..,_...--------(b)( 6)j CbH~Josie Gold ing Subject: Re: Teleconference Dear Jeremey, Ron and all, Thanks for invitin g_m__e on the call vesterda . (b)(5) ~ (b)( 5) NIH-0023 18 (b)(5) Best, Andrew On 2 Feb 2020, at 08:40, Jeremy Farrar________ Cb _>_<6) ... wrote : Thanks Ron (b) (5) Thoughts on tbat very welcom e. On 2 Feb 2020, at 08:30, R.A.M. Fouchier.._ _____ ....i..._'-"> wrote: Dear Jeremy and others, This was a very useful teleconference. (b) (5) (b) (5) Thanks for organizing this on such short notice, Kind regards NIH-0023 19 Ron Ron's noUtfe~s? _;, :______________________ NIH-002320 71i (b,JiH ~5J (b)( 5) NIH-002321 (b)(5) Van : Jeremy Farrar (b)( Datum : zaterdag 1 februari 2020 om 21:59 Aan: "Fauci, Anthony (NIH/NIA ID) [ E]" ------Cb -H= .-.-6)>, Patrick Vallance (b)(6) (b)(6) "M . Koopmans" CC: Christian Drosten (b)( 6), "R.A.M. Fouchier" (b)( , Edward Holmes -------.....::=~~;-7."'.::-:-"'"".""".'-:---:-:--::-- =========~~--========:------ (b)(6) CbH6), Andrew Rambau "Kristian G. Andersen" (b)(6) (b)(6), Paul Schreier (b)( (b)(6), ...========= "Ferguson, Mike" (b)(6) Francis Collins (b :)::: ::: (6) ~-------- (b)(6), (b)(6)>, Josie Golding 0nd erwerp: Re: Teleconference Thank you to everyone for joining. There is clearly much to understand understand in this. This call was very helpful to hear some of our current understanding and the many gaps in our knowledge. (b)(5) (b)(5) NIH-002322 (b) (5) I hope that is a reasonable approach, please send any thoughts or suggestions. Once again, thank you for making time over a weekend and for such an informed discussion on a complex issue. Thank you and best wishes Jeremy From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 -------~ To: "Fauci, Anthony (NIH/NIA ID} [E]" Vallance (b)(6) Cc: "Drosten, Christ ian" = (b)(6)>, >, Marion (b)( Koopmans Patrick (b)(6) II (b) (6) Edward rHolmes _... ...=====================...... (b)(6) ~ )~<6) (b ~.~------------- (b)( ~ "Kristi an G. Andersen " =========-=-=~ ----------~= (b)( ~, Paul Schreier( ===========-~~--- (bH ~> , (b)( ~ Michael FMedSci (b)( ~ Subject: Teleconference 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour NIH-002323 6am Sydney 8pmCET 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • • • • • Introduction, focus and desired outcomes - JF Summary - KA Comments - EH Q&A-AII Summary and next steps - JF Kristian Anderson Bob Garry- I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance An drew Rambaut Institute for Evo lutionary Biolog y Ashworth Laboratorie s, University of Edinburgh , Ed inburgh , EH9 3FL , UK conta c t - _____ ....,_ ~..,_ ( .,,. I http://tree.b1o.ed.ac.uk I te l ____ ..,._,, )..,§) The University of Edinburg h is a charitable body, registered in Scotland, with registration number SC005336. NIH-002324 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:45:28 +0000 Goldner, Shannah (NBCUniversal);Conrad, Patri cia (NIH/NIAID) [E] RE:Thank you so much To: Subject: My pleasure! From: Goldner, Shannah (NBCUniversal) Se nt: Sunday, February 2, 2020 10:33 AM To: Conrad, Patricia (NIH/NIA ID) [E)-------=(bc)(=6) Fauci, Anthony {NIH/NIA ID) [El (b)(6) Subject: Thank you so much Dr. Fauci, thank you so much for mak ing time for our show th is morning. We are very grateful to have you on, sharing your know ledge on this issue. I know you are extremely busy, but again, so many thanks . Sincerely - and have a good day, though I know a busy one . Shannah And Patric ia, thank you so much for your help and patience w ith me, I appreciate it. Shannah From: Conrad, Patricia (NIH/NIAID) [El Se nt: Saturday, February 01, 2020 8:42 PM (b)(6)> To: Goldner, Shannah (NBCUniversal) ; Fauci, Anthony (NIH/NIAID ) [El (b)(6) Cc: Antoniak, Cynthia (NBCUniversal, MSNBC) Subject: [EXTERNAL] Re: details re tomo rrow's MSNBC morning interview Adding dr Fauci here - he will arrive at the Nebraska ave stud io no later than 710 am for your 730 am ET live hit as per below. If there are any changes or cancellations in the morning please call his cell at (b)(6) Thank you. Sent from my iPhone On Feb 1, 2020, at 8:32 PM, Goldner, Shannah (NBCUniversal) wrote: NIH-002328 ----- (b)(6) , My cell is Patricia, hi. ..the contact at the NBC bureau (4001 Nebraska Ave) is Parita Desai. The number at the studio is 202-885-4800. The bureau is aware that Dr. Fauci is driving himself and he can park at the bureau. The interview time is scheduled for approx 7:30am, so if he can be at the studio by 7am for powder and to be seated, that would be appreciated . The producer in NY who will email you the information details for the segment tomorrow is Cyndi Antoniak . If you need to reach her before she reaches you in the morning , her email is Cynthia .ant oniak@nbcuni.com and her phone number is (b)(6) The interview is one on one with our anchors Kendis Gibson and Cori Coffin . If you need more information, please let me know . Thank you for your help and your pat ience today, I appreciate it. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 C: (b)(6) From: Conrad, Patricia (NIH/NIAID) [El ----------- (b)(6) Date: Saturday, February 01, 2020 7:54 PM To: Goldner , Shannah (NBCUniversal) Subject: [EXTERNAL]RE:Thank you so much Hi - are we firm for to morrow ? need onsit e cont act info ..t hx From: Goldner, Shannah (NBCUniversal) Se nt: Saturday, February 1, 2020 1:28 PM To: Conrad, Patricia (NIH/NIAID) [El Cc: Routh, Jennifer (NIH/N IAID) [E]:.=======~ (b~ H~ Stover, Kathy {NIH/NIAID) --------..-;:= [El CbH6)> Subject: RE:Thank you so much I will forward all tha t soon . Thank you! From: Conrad, Patricia (NIH/NIAID) [E] CbH ,> Date: Saturday, February 01, 2020 1:26 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/NIAID) [E] (b)(6); Stover, Kathy (NIH/NIAID) [E] (b) (6) Subject: [EXTERNAL]RE: Thank you so much NIH-002329 Yes - he can do that hit time - just let us know when it is firm. He will drive his car to the studio . I will need an onsite name and cell number for him at the studio herein de From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 1:20 PM To: Conrad, Patricia (NIH/N IAID) (E]-------(b ...)""'(6) = Cc: Routh, Jennifer (NIH/N IAID) [E] [E] (b) (6) Subject: Thank you so much (b)(6); Stover, Kathy {NIH/NIA ID) Import ance: High Patricia, hi, thank you so much fo r getting back to me and again, apologies to Dr. Fauci, I do understand how swamped he. With that said, I'll confirm the exact time at around 2pm our time, but I think the interview will be at approx 7:30am. Would you like me to arrange transportation to and from the studio? We'd like Dr. Fauci to be at the studio by 7:10am-ish? Thank you so much . Shannah (b)(6) From: Conrad, Patricia (NIH/N IAID) [E] Date: Saturday, February 01, 2020 12:41 PM To: Goldner, Shannah (NBCUniversal) Cc: Routh, Jennifer (NIH/N IAID) [E] (b)(6)>; Stover, Kathy {NIH/NIA ID) [E) (b)(6) Subject: [EXTERNAL]FW: request for a live interview tomorrow morning, on MSNBC Importance : High --------- Good afternoon - I believe we can make this work - if we can - it would need to be done in your NBC Studio in WDC at 4001 Nebraska Ave NW Will that work and what would the exact hit time be? NIH-002330 From: Goldner, Shannah (NBCUniversal) Date: Saturday, February 1, 2020 11:09 AM ------~~ To: Fauci, Ant hony (NIH/NIAID ) [E] (b)(6) Subject: request for a live interview tomorrow morning, on MSNBC Import ance: High Dr. Fauci, goo d morning. Are you available to do an inte rview tomorrow sometime in the 7:30 to 8am ET hour, to discuss the latest news about the Coronavirus? The interview would be one on one and approx 5mins . I saw you on t he Today show yesterday and I would love to get you on MSNBCto discuss this, I know our viewers will have a better understanding of the situation if you can take us through it I can arrange a satellite location/transportation/whatever is needed to make this work out. Thank you for your consideration and I hope to hear from you soon. All the best, Shannah Shannah Goldner MSNBC W: 212-664-1289 (b)(6) C: ----- NIH-00233 1 From: Date: Fauci,Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:44:24 +0000 Daley, George Q. Cc: Collins, Francis {NIH/OD) [El [El;Graham, Barney(NIH/VRC) [El Subject: RE: Inquiry and possible pone call To: ------ (b)(6));Marston, Hilary {NIH/NIAID) George: Thanks for the note . There is a lot of communications between scientists in China and their colleagues in the USA, many with whom they have been collaborating prior to the outbreak. There is no real "coordination" of this response since we do not know who is doing what until we are to ld - just like you have done here. Dr. Soumya Swaminathan, Chief Scientist at WHO is organizing a meeting on Feb. 11 -12 in Geneva to try and develop a research agenda for nCoV. I am sure tha t Chinese scientist s will be there. It might be helpful to contact her. Her e-ma il address is (b)( . I hope that this is helpful. I wi ll follow-up with a call. Best, Tony From: Daley,George Q. Se nt: Sunday, February 2, 2020 10:32 AM To: Fauci, Anthony {NIH/NIAID) [El (b)( > -----------------~~ --------- (b)(6)> (b)( ; Fauci, Anthony {NIH/N IAID) (El Subject: Inquiry and possiblepone call Dear Tony , Alan Garber , Harvard 's Provost , and I met yesterday with a team led by Jack Xia , the CEO of China's Evergrande Company , and Dr Jack Liu, Evergrande 's chief health officer, who stated thy were acting on behalf of Dr Zhong Nanshan , China's ke point 4 person on the coronavirus outbre ak see below . CbH> , and --------------------------they arranged a conference call for tomorrow morning EST with Dr. Zhong. While I have been mobilizing efforts of our community to react to the virus and to this request , I am not na"i"v e to the challenging politics of such a relat ionship. I do not want to compl icate or duplicate efforts already underw ay, and am writing to request NIH-002332 whatever information you are willing to share on your current efforts to coordinate a response. If a phone call is more facile, please do not hesitate to try my cell: (b)(6) anytime today. ------ Sincerely, George George Q. Daley, MD, PhD Dean, Harvard Medical School Caroline Shields Walker Professor of Medicine Professor of Biolog ical Chemistry and Molecular Pharmacology Office of the Dean, Gordon Hall 25 Shattuck Street, Boston MA 02115 Contact: Cb> (6) (b)(6) Cb)(6) Date: Saturday, February 1, 2020 at 11:26 PM To: Public HMS Email From: Jack Liu Cc: i~fflf!'f CbH6) (b)(6), M~~ Min Chen (b)(6) Subject: Follow up on today's meeting Dear Dr. Daley: Per our discussion this afternoon in the conference room at your school, NIH-002333 -------- (b) (4) Jack Liu, MD NIH-002334 Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 15:33:34 +0000 To: Collins, Francis (NIH/OD) [El Cc: Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie {NIH/OD) [El;Conrad, Patricia (NIH/NIAID) [El;Cassetti, Cristina (NIH/N IAID) [El;Marston, Hilary {NIH/NIAID) [El Subject: RE:2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ From: Date: Francis: Th is is a meeting aimed at setting research priorities and I do not believe that it impacts or overlaps with the Tedro s proposal. I will have my staff submit some names (mostly high level program people) to represent us at this meeting. Tony -------2, 2020 10:11 From: Collins, Francis (NIH/OD) [E] Date: Sunday, February AM To: Fauci, Anthony (NIH/NIAID) [El-----Cc: Tabak, Lawrence (NIH/OD) [E] (b)( 6) (b)(6) (b =)c-c (= > --------- (b)(6) ; Wolinetz, Carrie (NIH/OD) [E) Subject: FW: 2019 novel Coronavirus Global research and innov ation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Hi Tony , Just encounte red this message from Soumya of WHO, inviting attendance at a meeting in Geneva on Feb. 11- 12. I'm not sure how that will fit with the Tedros proposal. Who would be the right persons from NIH to propose for Soumya's meeting? Francis From: SWAMINATHAN, Soumya ________ Cb) _C _> Date: Friday, January 31, 2020 4 :41 AM (b)(6) Collins, Francis {NIH/OD) [E] ------Cc: SATHIYAMOORTHY,Vaseeharan (b)(6) (b)(6)>; RIVEROSBALTA,Alina Ximena (b)(6); BORGES,Andrea (b)(6); MCLELLAN , Faith (b)(6)>; HILL, Suzanne Rose (b)(6); GARAPO,Charity Helen (b)(6)> (b)(6) NIH-002335 Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Dear All, I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus. The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward . Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an impor t ant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting. I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (bH and (b)(6) in your response. With best wishes, Soumya Chief Scientist NIH-002336 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 12:35:48 +0000 Lorsch,Jon (NIH/NIGMS) [El RE:Update from Ming Exhausted, but OK. Thanks. -----Original Message----From: Lorsch, Jon (NIH/NIGMS) [E] Date: Sunday, February 2, 2020 7:35 AM To: Fauci, Anthony (NIH/NIAID) [E] ...______ (b)(6) ------~= _> Cb _<.... Subject: Re: Update from Ming (b)(6) J hope you are hanging in there! Jon On 2/1/20, 11 :20 PM, "Fauci, Anthony (NIH/NIAID) [E]" ______ Cb _H_6)> wrote: Jon: (b)(6) Best, Tony _____ _ -----Original Message----From: Lors ch, Jon (NlH/NIGMS)[E] .....,. Date: Friday, January 31, 2020 6:57 AM To: Fauci, Anthony (NIH/NlAID) [E]._______ Subject: FW: Update from Ming (b)( Cb _H_6l Tony, (b)(6) Jon On 1/31/20 . 5:32 AM, "Lei. Ming (NIHNIGMS) [E]" ------- Thanks~J~o=n_._ . ------------------------------~~ CbH > wrote: (b)(6) Ming Sent from my iPad NIH-002337 - > On Jan 31, 2020, > > T hanks, Ming. at 6:08 PM , Lorsch, Jon (NIH/NIG MS) [E] ------- (b) (6) > --------------- > > On I /30/20, 9: IO PM, "Lei, Min g (NTH/NIGMS ) [E]" ______ > wrote: (b)(6) Cb _)_(6) _ > wrote: > Jon , > > Here is an uodate of mv situation: (b)(6) > > Best. > Ming > NIH-002338 From: Date: To: (NIH/OD) [El Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 11:26:13 +0000 Collins, Francis (NIH/OD) [El;Tabak, Lawrence (NIH/OD) [E];Wolinetz, Carrie RE: More on evolution of coronavirus The Indian paper is really out landish. Agree about Jon Cohen's nice summary. From: Collins, Francis (NIH/OD) [E] Se nt: Sunday, February 2, 2020 5:58 AM To: Fauci, Anthony (NIH/NIAID) [El (b)(6) ------~~ Tabak, Lawrence (NIH/OD) [El (b)(6)>; Wo linetz, Carrie (NIH/OD) [El CbH > Subject: More on evolution of coronavirus (b)(6); --------- In case you haven' t seen, attached is the Indian paper claiming HIV sequences have been inserted into 2019-nCoV, which has been roundly debunked. I found Jon Cohen's piece in Science to be a pretty useful summary : https://www .sciencemag .org/news/2020/01/mining -coronavirus -genomes -clues-outb reak-s-origins FC NIH-002339 From: Date: To: Subject: Attachment s: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:24:27 +0000 Cassetti, Cristina (NIH/NIAID) [E] (b)(4l Pleasehandle. ------------------------ From: Ryan Muldoon Se nt: Thursday, January 30, 2020 3:33 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b)(4) Subject: (b)(6) (b)(6) Dear Tony, (b) (4) Kind regards, Ryan PrEPB1opharrn Ryan Muldoon CEO Tel : Email (b)(6) --=======L----- ~= -----------www .prepbiop harm.com (b) (6) NIH-002340 From: Date: To: Subject: Review ( Chinese) Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:2 1:44 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Dear Prof. Anthony Fauci, here is a request from MIT Technology NIA ID inquiries, p lease. From: Tao Sun Cb)(6) Se nt : Friday, January 31, 2020 2:06 AM To: Fauci, Anthony (NIH/NIAID) [E]______ Cb> _C6) _> Subject: Re: Dear Prof. Anthony Fauci, here is a request from MIT Technology Review (Chinese) ------~~ Dear Prof. Anthony Fauci, Thank you. Dr. Catharine provided me useful information . As the epidemic develops, here are a few new questions to ask. Chinese readers want to know the opinions of foreign independent experts 1 Some media said Wuhan vi rus' fatality rate approaches that of the flu, saying that people need not panic. What do you think of this view? In reality, Chinese residents are already scared and are already rushing to buy masks. 2 ROis a developing number, and it is not easy to calculate. Does it make sense to talk about ROat this stage? 3 You had talked about asymptomatic patients, and how public health workers should treat asymptomatic people? AND why are some viral infections asymptomatic? Can they wear masks to help prevent epidemics? 4 To what extent will the closure of Wuhan preven t the epidemic? Looking forward to your reply . Best Tao Sun -------- CbH6)>-=f2020~1.F3 24 B ffl]3i '"F.q:.3:4S~ii : Dear Prof . Anthony Fauci, I am Tao Sun, a repor ter from Beijing. I am currently writing reports for t he M IT Technology Review (Chinese) . JAMA published your article Coronavirus Infections-More Than Just the Common Cold, and Xinhua News Agency reported this article . Here are some questions I would like to ask you . 1 Some peop le think that it is not necessary to develop a new vaccine against SARSor coronavirus in NIH-00234 1 Wuhan. The reason is that, firstly, there is no commercial interest to pharmaceutical manufacturers, and secondly, such outbreaks may not return after the extinction. What do you think of these views? 2 For the Wuhan virus vaccine being developed, the epidemic is likely to be elimina ted after three months, so is it still necessary to develop a vaccine? 3 You can talk about SARS.How muc h does a vaccine against SARSactually play? Looking forward to your reply . TAO SUN DEEPTECH MIT Tech nology Review (b)(6) suntao@mittrchina.com 7th FL, Tower AB Office Park, 10 Jintong Wes t Road, Chaoyaa g District, Beijing htt p ://www. m it tr ch ina .co m TAO SUN DEEPTECH MIT Technology Review (b)(6) suntao@mittrc h ina .com 7th FL, Tower AB Office Park, 10 Jintong West Road, Chaoyang District, Beijing ht tp :// www.m itt rchina.com NIH-002342 From: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 04:08:48 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Strategy to attack 2019-nCoV coronavirus Date: To: Subje ct : Please handle. From: Jingyue Ju (b)(6) Date: Friday, January 31, 2020 12:39 PM ----------------_ _ ___: _;., ~------------------- To: Fauci, Anthony (NIH/NIAID) [E] · _:_ Robert R. (CDC/OD) (b)(6) Cc: Mary C Boyce (bH ; Lee Goldman (b)(6) L. Subje ct : Strategy to attack 2019-nCoV coronavirus ----------- ---------- -,;-;-= (b)(6); Redfield, (b)(6)>; Shelanski, Michael Dear Drs. Fauci and Redfield, (b) (4) Please let me know if you would like to receive the full manuscript. Thank you very much for your consideration . Sincerely, Jingyue Jingyue Ju, Ph.D. Samuel Ruben-Peter G. Viele Profe ssor of Engineering Professor of Chemical Engineering and Pharmacology Director, Center for Genome Technology & Biomolecular Engineering Columbia University Northwest Corner Building, Room lOOOMl NIH-002343 Phone: (b)(6)(0ffice) ____ _, (Cell) (b)(6) Fax: 212-851-9330 Email: (b)(6) NIH-002344 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 04:08:13 +0000 Arnold Manto RE:Coronavirus issues Arnold: Thanks for the note. I actually have recommended to several press people that they contact you when they ask for non-government experts. I will continue to do that. Best, Tony From: Arnold Manto (b) ( > Date: Friday, January 31, 2020 1:03 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Coronavirus issues ------~~ -------- (b)( > Hi, Tony: As this progresses, and as other news items quiet, I am concerned that this is not being handled like the 2009 pandemic when you and Rich Besser functioned as someth ing like a tag team . This gets really t ricky when public health interventions are the way SARSwas handled and remain the focus. I am being contacted by the media currently, not because I was in Beijing at the end of SAR$but because of general epidemiology creden t ials I am t rying to put things into context based on past histo ry, even though I know other sensational information may come to light which will further muddy the waters. And we know who will be the main muddiers Keiji put me on the 2009 WHO Emergency Committee as a non-governmental person who was not bound by clearances etc I am trying to figure out if I can play that role here I have not yet been contacted by Elizabeth Cohen, our mutual friend, but I am sure I will.The one thing I can do is to try to (b) (4) I am attaching a paper which I wrote post 2009 wh ich shows how the way it was handled adversely affected programs in much of Europe It might be of interest to those who were not around at that time . Regards Arnold Arnold S. Manto, M.D. Thomas Francis Collegiate Professor Department of Epidemiology School of Public Health University of Mich igan 1415 Washington Heights Ann Arbor, Ml 48109-2029 Tel: (b)(6) Fax: (734) 764-3192 (b)(6) NIH-002345 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:50 +0000 toygar civelek RE:Coronavirus Many thanks! ---------- From: toygar civelek Se nt : Friday, January 3 1, 2020 2:09 PM To: Fauci, Anthony {NIH/NIAID) [E] Subject: Coronavirus ------- (b) (6) > --------- ~= (b)(6) Dear Mr. Fauci, I am hoping that this email reaches you as I saw this email address on line on the NIH website. As we as the public get to hear, read and see with the current coronavirus scare, here in the US and worldwide, it is comforting to have professionals and experts like you, who really know what t hey are talking about , wha t is going on, what can be done, timelines, action plans, and inform the public in a reliable and comforting way, yet being very transparent, informing the public on social media. Kudos to you sir and please keep up the excellent work. Sincerely, Mur. Civelek NIH-002349 From: Date: To: Cc: Folkers-------- Fauci, Anthony (NIH/NIAID) [E) Sun, 2 Feb 2020 04:01:28 +0000 Conrad, Patricia (NIH/NIAID) [E) Greg Folkers (b~ ~ )(=6) (b)( ·Barasch, Kimberly (NIH/NIAID) [C];Greg Subject: FW: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Attachments : Fauci, Anthony Feb. 2020 lnvitation .docx, BCActive Members Jan. 2020.pdf I defin itely want o do this. Please respond. Thanks. From: Marlene Colucci Date: Friday, January 31, 2020 2:00 PM ~= To: Fauci, Anthony (NIH/NIAID) [E]------(b)(6) Cc: Conrad, Patricia (NIH/NIAID) [E] (b)(6) David Rubenstein ; MaryPat Decker Subject: Business Council - Invitation to speak at the February 20-21, 2020 meeting at the Ritz Carlton (22nd and M St. NW), Washington, D.C. Dear Dr. Fauci, On behalf of our co-chairs for the winter meeting of The Business Council, David Rubenstein of The Carlyle Group and Ginni Rometty of IBM, we would like to formally invite you to participate in our meeting on February 20-21, 2020 in Washington, D.C. The theme of the meeting is "The Next Decade." (See formal inv itation attached as well as list of CEO members). We wou ld like for you to participate in a 50 minute fireside chat with David Rubenstein (and possibly Dr. Francis Collins) to discuss the current coronavirus as well as what we should expect in the next decade. We want to give our CEOsinsights into wha t the next 10 years will bring in terms of detect ion, diagnosis and treatment of diseases. All conversations are strictly off the record and closed press. We will cover all lodging and transportation. As you know, The Business Council is comprised of the chief executive officers of the largest global corporations, representing all segments of the economy. We expect at least 150 CEOmembers, spouses and speakers to be in attendance. As a participant you and your spouse are also invited to join us for our special reception, dinner and speaker at the REACH(Kennedy Center) on Thursday, February 20 at 6:30pm. It is the best op portunity for you to meet our CEO members and spouses, speakers and other special guests in an informal atmosphere. If you are interested and available, please let me know. We can also set up a very brief call with you to discuss any additional details and answer any questions you may have. We look forward to hearing from you and would be honored to have you participate with us again. Warmest regards, NIH-002350 Marlene Marlene Colucci EXECUTIVE DIRECTOR 'I ~ BUSINESS COL NCIL T: 202-298 -7650 C: (b)(6) F: 202-785-0296 NIH-002351 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sun, 2 Feb 2020 03:48:52 +0000 Morens, David (NIH/NIAID) [E] RE: Potential PHS Officer Deployment To: Subject: Got it. From: Morens, David (NIH/NIAID) [E] Date: Friday, January 31, 2020 4:54 PM (b)(6) ---------- To: Fauci, Anthony (NIH/NIAID) [E] -------= (b-c)(c-= 6); Auchincloss, Hugh (NIH/N IAID) [ E] (b) (6) > Subject: Potential PHS Officer Deployment Tony & Hugh, in follow up, the PHShas informed all PHSofficers that as of 2/3 they are subject to deployment for coronavirus work "without supervisory approval", meaning that if needed, officers can be deployed and assigned anywhere, for indefinite periods, by the Assistant Secretary of Health. We are hearing that many officers, especially physicians and nurses, may be deployed for quarantine efforts and to assist State agencies. I haven't heard anything personally, but just want to let you know. These deployment orders can come with almost no advance warning, although I don't expect that. David M. Morens, M.D. CAPT, United States Public Health Service Senior Advisor to the Director Office of the Director National Institute of Allergy and Infectious Diseases National Institutes of Health Building 31, Room 7A-03 31 Center Drive, MSC 2520 Bethesda , MD 20892 -2520 a [l§] Q (assistants : Kimberly Barasch; Whitney Robinson) (b)(6) 301 496 4409 (b)(6) Disclaimer: This messageis intended for the exclusiveuse of the recipient(s)named above. It may contain information that is PROTECTED, PRIVILEGED,and/or CONFIDENTIAL, and it should not be disseminated,distributed, or copiedto persons not authorized to receive such NIH-002354 information. All sensitive documents must be properly labeled before dissemination via email. If you are not the intended recipient, any dissemination, distribution, or copying is strictly prohibited. If you have received this communication in error, please erase all copies of the message and its attachments and notify us immediately. NIH-002355 From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [El Sun, 2 Feb 2020 03:28:01 +0000 Cassetti, Cristina (NIH/NIAID) [El FW: Control 2019-nCoV Wuhan Please handle. From: (b)(6) Date: Saturday, February 1, 2020 8:21 PM To: Fauci, Anthony {NIH/NIAID) [E] Subje ct: Control 2019-nCoV Wuhan ------~~ -------- (b)(6)> Tri-Prime Gene Pharmaceut ical Co Beijing China Cheng YongQing CEOTri-Prime Gene. regards My name is Robert Vera. I amEj years old. I live in (b)(6) Ecuador South Amer ica. Here in Ecuador in 1999 in shrimp farms in Ecuador there was a lethal disease among shrim p called the white spot vir us syndrome . He appeared in 1999 in Ecuador and made shrimp sick and eliminated them. In China it appeared in 1993. White spot virus syndrome is caused by a virus from the nimavir idae family that infects a vi bran parahaemolitycus . I applied more than 10 billion liters of natural and organic biolog ical molecules of my invention for 10 years from 2002 to 2011 in more than 10 thousand hectares of shrimp farms. These molecules have antiviral characteristics and inhibit the glycoproteins of viruses. These glycoproteins are what open cell receptors to infect and replicate. Also these nat ural molecules invented in (b)(6) Ecuador in 2001 inhibit the cytokinins that inflame hepat opancreas. Cytokinins cause the desquamation of epithelial cells from t ubules that end up collapsing to the liver and shrimp pancreas. These viruses infect the parahaernolitycus vibrating bacteria and create an incurable syndrome in the shrimp. In 2002 we defeated this disease and contro lled it ... with this Ecuador to produce little shrimp, now in 2019 it is the number one in the world to export shrimp. In the same way, the coronavirus 2019nCoV Wuhan infects the pneumococci of the lung and the respiratory syndrome develops. Wuhan coronavirus is the seventh among the coronavi ruses after sars and mers. Another 4 are simpler in animals th at cause the flu. 2019-nCoV causes 2% of deaths. There are 250 dead as of January 31, 2020 and more than 10 thousand infected in China. 20 count ries have infections. It is tr ansmitted even without symptoms and its incubation is 2 to 14 days. We can spray with more than 1000 million liters of these virus inhibitory molecules throughout Wuhan . 1 million hectares (10,000 m2) can be fumigated by fumigation planes as they are made in banana plantations in Ecuador. We can inhibit all viruses with bacteria and biological molecules to inhibit viruses. And we can give them more than 100 million liters to take for more than 100 million liters for humans to more than 100 million inhabitants of the entire province of Hubei in China, so that they do not transm it coronaviruses ... and the seriously ill can also heal They are natural antibacterial, anviral and antifungal biological molecules ... they are immune regenerati ng cell bioimmunmodulato rs and immune boosting imm une response in immunocompromised people who have diabetes and high blood pressure. Others may have cytokinin and immunoglobulin problems . We can fi nish with the 2019-nCoV Wuhan in the environment and in humans so be found in the lungs whose epithelial cells are already collapsing with an increase in inflammation and difficulty breathing . We can beat the coronav iruses NIH-002366 thro ughout China. At te Robert Vera Graduated from the What asp p ----.!:=======~~---------(b) (6) a. 1919 ~ ------------s -;:; ,.,, 4¾ e n N. R. C. I.a. C,t?I A...tua ado 27/01/2020 10;0'1, Enviadodesde mi smartphone Samsung Galaxy. NIH-002367 (b)(6) From: Date: To: Subject: Fauci, Anthony (NIH/NIAID) [E) Sat, 1 Feb 2020 23:56:07 +0000 Jason Gale RE: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Thanks, Jason. Best regards, Tony From: Jason Gale (BLOOMBERG/ NEWSROOM:) Date: Saturday, February 1, 2020 6:20 PM To: Fauci, Anthony (NIH/NIAID) [E)______ ..,, (b""" )(=6) Subject: (BN) Coronavirus Lurking in Feces May Reveal Hidden Risk of Spread Hello Dr Fauci , Just been watching the press conference on You Tube with you and your federal colleagues. Thought you might find this in teresting, if you have time to breat he let alone read media reports! All the best and hope to see you at the end of next month . Jason Coronav irus Lurking in Feces May Reveal Hidden Risk of Spread 2020-02 -01 06:55 :00.469 GMT By Jason Gale (Bloomberg) -- While doctors have focused on respiratory samples from pneumonia cases to identify coronavirus patients, they might have ignored a less apparent and hidden source of the spread: diarrhea . The novel coronavirus was detected in the loose stool of the first U.S. case -- a finding that hasn't featured among case reports from Wuhan, China, the epicenter of the outbreak. However, that doesn't surprise scientists who have studied coronaviruses , nor doctors familiar wit h the bug that caused SARS. Diarrhea occurred in about 10-20% of patients afflicted with severe acute respiratory syndrome about 17 years ago and was the source of an exp losive SARSoutbreak in the Amoy Gardens residential complex in Hong Kong. SARSand Wuhan viruses bind to the same distinctly shaped protein receptors in the body that are expressed in the lungs and intestines, making these organs the primary targets for both viruses, said Fang Li, an associate professor of veterinary and biomedical sciences at the University of Minnesota. The discovery of the Wuhan virus, dubbed 2019-nCoV, in the fecal material of the 35-year-old man treated at the Providence NIH-002370 Regional Medical Center Everett in Washington is "interesting," said Scott Lindquist, the state epidemiologist for infectious disease at Washington's Department of Health. "That adds to the knowledge about this,'1 he told reporters on a conference call Friday. "It's not only excreted in your respiratory secretions, it's also secreted in your stool." Read More: What You Need to Know About the Spreading Coronavirus Researchers don't yet know how exactly 2019- nCoV spreads from person to person, but suspect it's most likely from coming into contact with virus -containing droplets that could be emitted by an infected person's cough and transferred to their hands or surfaces and objects. Face Masks That's led to a run on face masks. But those may be of limited benefit in the event the virus is being transmitted via the fecal-oral route, said John Nicholls, a clinical professor of pathology at the University of Hong Kong. Squat latrines, common in China, lacking covers and hands that aren't washed thoroughly with soap and water after visiting the bathroom could be a source of virus t ransmission, said Nicholls, who was part of the research team t hat isolated and characterized the SARSvirus. A virus-laden aerosol plume emanating from a SARSpatient with diarrhea was implicated in possibly hundreds of cases at Hong Kong's Amoy Gardens housing complex in 2003. That led the city's researchers to understand the importance of the virus's spread through the gastrointestinal tract, and to recognize both the limitation of face masks and importance of cleanliness and hygiene, Nicholls said in an interview. "I think in Wuhan, that would be a very likely place where you might get the transmission" from fecal material , he said. "If it's using the same receptor as for SARS,I can't see why it shouldn't be replicating in the gut." Nicholls and colleagues at the University of Hong Kong are testing laboratory models of human tissues and specimens to understand where and how the Wuhan virus replicates, he said. Emerging Evidence Doctors have reported diarrhea infrequently in 2019-nCoV patientsadmitted to Wuhan hospitals , though it's been more prominent among reported cases outside the city, including members of a Shenzhen family infected in Wuhan, and more recently in the first U.S. case in Washington state . That patient exper ienced a two -day bout of diarrhea from which a NIH-002371 sample tested positive. The lab in Washington didn't attempt to grow the virus from that specimen, said Lindquist, the state epidemiologist, "because it wasn't going to add anything to his care." Many of the emerging coronaviruses are so-called pneumoenteric viruses, meaning they can replicate both in the respiratory tract and the gastrointestinal system, said Ralph Barie, professor of microbiology and immunology at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill, who has studied coronaviruses for decades. Overwhelmed by hundreds of severely sick pneumonia patients, doctors in Wuhan might not have focused on any gastric signs, Barie said in a phone interview. 'So Overwhelmed' "The Chinese are so overwhelmed at the moment and trying to do a combination of treating patients and dealing with t he scope of the outbreak, and then trying to get out papers that describe what's happening," he said. Any virus in stool is more likely to be present during the acute phase of an infection, occuring before hospitalized patients develop a life -threatening complication known as acute respiratory distress syndrome, Barie said. "I have also spent most of my time focusing on the respiratory tract symptomology rather than the gut because of the relationship between these different emerging viruses and acute respiratory distress syndrome," he said. Zijian Feng, deputy director general of Chinese Center for Disease Control and Prevention, and colleagues released a report Wednesday on the first 425 Wuhan cases, and noted that early infections that didn't appear to display typical signs -- such as fever and viral pneumonia -- or had mild symptoms might have been missed. "The initial focus of case detection was on patients with pneumonia, but we now understand that some patients can present with gastrointestinal symptoms," Feng and co-authors said in their report, which was published in the New England Journal of Medicine. Emerging evidence of virus-containing diarrhea warrants further investigation, said Peter Collignon, a professor of clinical medicine at the Australian Nationa l University Medical School in Canberra, who advises the Australian government on infection control. "This is something new," Collignon said in an interview. "We presume it's respiratory droplets, but with SARSthere was evidence of other routes . We have to keep an open mind." NIH-002372 To contact the reporter on this story: Jason Gale in Melbourne at j.gale@bloomberg.net To contact the editors responsible for this story: Brian Bremner at bbremner@bloomberg.net ; Shamim Adam at sadam2@bloomberg.net NIH-002373 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 23:19:46 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: article from IIT/lndia on Coronovirus Date: To: Subject: (b) (4) Please handle. From: Hong Cai (b)(6) Date: Saturday, February 1, 2020 5:33 PM To: WRB Gmail ; Fauci, Anthony (NIH/NIAID) [E] Subject: Re: article from Ill /India on Coronovirus -------- (b) (6) > Dear Fauci, I knew you must be super busy with the recent Coronavirus outbreak. --"e-':========- (b)(4 J (b) (4) Thank you for your assistance in advance! h"" -mesabiotec ~, (- Hong Cai, Ph.D Co-Founder and CEO Mesa Biotech, Inc. 6190 Cornerstone Court East, Suite 220 San Diego, CA 92121 www.mesabiotech.com (b)(6) (b)(6) ----------- From: WRB (b)(6) Date: Saturday, February 1, 2020 at 7:27 AM NIH-002374 (b)(6) To: "Anthony (NIH/NIAID) Fauci [E]" Cc: Hong Cai (b)(6) Subject: article from IIT/lndia on Coronovirus Hi Tony, I hope you are coping with the chaos around coronavirus. (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is try ing to replicate this study or to find problems with the ir methodology. With best wishes, Bill William R. Brody (b)(6J ~ohns Hopkins University Salk Institute for Biological Studies -------- NIH-002375 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:06:26 +0000 Jeremy Farrar;Collins, Francis (NIH/OD) [El RE:Teleconference Thanks, Jeremy. We really appreciate what you are do ing here. Pleasure to work w ith you. Best, Tony From: Jeremy Farrar ________ Cb _H_6)> Se nt: Saturday, February 1, 2020 4:00 PM To: Collins, Francis (NIH/OD) [El (b)(6)> Cc: Fauci, Anthony (NIH/NIAID) [El (b)(6) Subject: Re: Teleconference ----- ~= -------- We are altogether as you know! Conversations with you and Tony, and Patrick and others - always great working with you both From: Francis Collins (b)(6)> Date: Saturday, 1 Februa ry 2020 at 20:50 To: Jeremy Farrar (b)(6) Cc: "Fauci, Anthony (NIH/N IA ID) [E]" Subject: Re: Teleconference ---------- (b)( Hi Jeremy, I can make myself available at any time 24/7 for the call with Tedros. Just let me know. Thanks for your leadership on this critical and sensitive issue. Francis Sent from my iPhone On Feb 1, 2020, at 3:07 PM, Jeremy Farrar ________ Cb _H_ > wrote: I have rejoined so a line is open if any help to rejo in. (b)(6)> From: Jeremy Farrar Date: Saturday, 1 February 2020 at 19:56 To: "Fauci, Anthony (NIH/NIA ID) (E]" _______ ---------- CbH >, M ichael FMedSci Vallance ------------- (b)(6) Subject: Re: Teleconference NIH-002376 Cb ~>~<, Francis Collins CbH6),Patrick Can I suggest we shut down the call and then redial in? Just for 5-l0m ins? (b)(6) From: Mar ion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jere my Farrar CbH6J> Cc: "Fauci, Anthony (NIH/NIA ID) [E)" ._____________ Cb _H_6)>, Patrick Vallance ------------ Cb)(~"Drosten, Christian" (b)(~ (b)(~, (b)({;j1>, Edward Holmes ! CbH6)>,"Kristian G. Andersen" ! "":' S-: ch_r_e"."" ie-r=1====-..;__----------====~ CbH~,Paul Cb "=' H"=' 6)] ::---- Cb)( ~ M ichael FMedSci f --======--~~ --------------Collins I CbH ~> Cb)( ~ Francis Subject: Re: Teleconference (b) (5) On 1 Feb 2020, at 19:12, Jeremy Farrar ---------- (b)(6)> wrote: Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Dat e: Satu rday, 1 February 2020 at 15:34 NIH-002377 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in detail s attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problem s If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST {Hope I have the times right!) Thank you for the series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut NIH-002378 Paul Schreier Patrick Vallance NIH-002379 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 22:00:47 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: FORYOUR REVIEW:Staff Communication on Novel Coronavirus Attachme nts: Draft_AIIStaff_Novel_Coronavirus_2.1.2020.docx, Draft_ OHR_Flexibilities_Novel_ Coronavirus_2 .1.2020.docx Please handle this. Thanks From: Myles, Renate (NIH/OD) [E] Se nt: Saturday, February 1, 2020 4:12 PM ------------To: Fauci, Anthony {NIH/NIAID) [El (b)( (b) ( ·> ..-.-,= Billet, Courtney (NIH/NIAID) [E] (b)(6b; >; Stover, Kathy (NIH/NIAID) [El (b)(6 h ; Routh, Jennifer (NIH/NIAID) [E) (b)( > Cc: Tabak, Lawrence (NIH/OD) [E] (b)( >; Gottesman, Michael (NIH/OD) [E] Cb)( ·; Johnson, Alfred (NIH/OD) [E] CbH >; Berko, Julie -:--.-:-:-:-:-:7.::====,........_ {NIH/OD) [El Cb)( ; McGowan, Colleen (NIH/OD/ORS) [El (b)(6); Burklow, John (NIH/OD) [E] Cb)( >; Chandler, Beth ":"" (N- IH - /-:-: 0-:D-:) :-: [E :-:; ) =====:...~ Cb ~) ~(6) Subject: FORYOUR REVIEW: Staff Communication on Nove l Coronavirus Good afternoon, Dr. Fauci and team: Working in coordinat ion with OHR, ORS,OIR, and others, we have developed two communication products to address questions/concerns that are being raised by NIH staff related to the novel coronavirus. The two products are: 1. All staff emai l from Dr. Collins to provide genera l information and guidance to NIH staff 2. QA for use by Executive Officers (not for broad distribution) on human resources flexibilities in response to coronavirus These products are provided for your review and guidance. We also plan to share with HHSfor review/awareness. The current plan to disseminate these products on Monday. We look forward to your input. Best, Renate Renate Myles, MBA Deputy Director for Public Affairs Office of Communicationsand Public Liaison NationalInstitutes of Health Tel: (b) (6) NIH-002380 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 20:03 :12 +0000 Jeremy Farrar RE:Teleconference Date: To: Subject: Yes From: Jeremy Farrar (b)(6) Se nt : Saturday, February 1, 2020 2:56 PM To: Fauci, Anthony (NIH/NIAID) [E]-------= (b)( ·; (b"'"" )= c >; Collins, Francis (NIH/OD) [E] (b)( ; Patrick Vallance Ferguson, Mike (b)(6) Subject: Re: Teleconference Can I suggest we shut down the call and then redial in? Just for 5-lOmins? ------------ From: Marion Koopmans Date: Saturday, 1 February 2020 at 19:43 To: Jeremy Farrar ! (b)(6) (b)(~ Cc: "Fauci, Anthony (NIH/N IA ID) [E]"f (b)( ~ >, Patrick Vallance ----""."-----:-:-:==:...-------~~ "Drosten, Christian" I (bH ~ , (b)(6) i>, (b)( ~ Edward Holmes (b)(~ >, (b)( ~ "Kristian G. Andersen" ! Pau l Schreier ! --===========~~-----~======~~M ichaeI FMedSci l FrancisCollins! -------------------Subject: Re: Teleconference (bH ~ >, (b)( ~ (bH ~ > (b)(5) On 1 Feb 2020, at 19:12, Jeremy Farrar --------- (b)(6)> wrote : Kristen and Eddie have shared this and will talk through it on the call. Thank you. NIH-00238 1 Hope it will help frame the discussions. From: Jeremy Farrar CbH6J> Date: Saturday, 1 February 2020 at 15:34 1st February(2nd Feb for Eddie) Information and discussionis sharedin total confidenceand not to be shareduntil agreement on next steps. Dial in details attached. Please mute phones. I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update. One Hour 6am Sydney 8pm CET 7pm GMT 2pm EST 11am PST (Hope I have the times right !) Thank you for t he series of calls and for agreeing to join this call. Agenda • Introduction, focus and desired outcomes - JF • Summary- KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten NIH-002382 Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002383 From: Date: To: Subject: Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 19:02:40 +0000 Auchincloss,Hugh (NIH/NIAID) [El FW: Offering assistanceduring this public health emergency Please handle. (b)(6) From: Albert Rizzo Date: Friday, January 31, 2020 5:11 PM To: Fauci,Anthony {NIH/NIAID) [E] (b)(6) ·_ _;__ _:_..:....: .!::::===-~:--Cc: Harold Wimmer (b)( Subject: Offering assistanceduring this public health emergency -------- ------~~ Hello Dr. Fauci: As the coronavirus continues to be a public health emergency, the American Lung Association is closely following guidance and repo rts being issued by NIAID, WHO, and CDC. Our Association is working to help relay impo rtan t public health information provided by the various agencies. As Chief Medical Officer for the American Lung Association, and with the full support of our CEO, Haro ld Wimmer, and our Board of Directors, I would like to offer the American Lung Association support on strategies that wou ld be appropriate for our organization to participate in or communicate. I am happy to discuss any potent ial opportunities in which you feel we may be of assistance . Sincerely, Albert A. Rizzo MD FACPFCCP Chief Medical Officer American Lung Association Cell (b)(6) NIH-002384 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:55:58 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: Consultancy request - Coronavirus To: Subject: Pleasehandle. From: Tatsch, Fernando Franciosi (b)(6)> Date: Friday, January 31, 2020 6:39 PM To: Fauci, Anthony (NIH/NIAID) [ E] --------=(b)'""'(= 6)> Cc: Bacher, Hans P (b)(6)>; Vallabh, Bhadrish Subject: RE: Consultancy reque st - Coronavirus (b) (6) > Dear Dr. Fauci, The below invitation is for a meeting identica l to an advisory board . We wonder if a short phone call could be beneficial to offer further context. With best regards, Fernando Tatsch FERNANDO TATSCH, MD, MBA Therapeutic Area Head - HCV / RSV Global Med ical Affairs 2SW 102 08 OFFICE I 1 N Wauk egan Rd I North (b) (6) I CELL Chicago, IL 60064 (b) (6) I EMAIL -------- (b = )~(6) = abbvie.com This commu nic;,ti on may con t;iin info r mation t hat is pro pr ietary, confident ial, or exemp t from disclosure. If you are not the inten ded r ecip ient, please note that any oth er dissemination , distrib ution, use or copying of this comm unication is strictly prohibi ted. Anyone w ho receives t his message in erro r should not ify the sender immed iately by telephone or by return e-mail and delete it from his or her computer. From: Tatsch, Fernando Franciosi Date: Thursday, January 30, 2020 4:53 PM To· (b)(6) Subject: Consultancy request - Coronavirus Dear Dr. Fauci, On behalf of AbbV ie, I would like to explore your interes t and availabi lity for a scientific consultation. AbbVie is interested in your scientific view of the 2019-nCoV epidemic. Your assessment will be very informa t ive for us in the context of NIH-002385 --------------- (b)(4) If you are interested, we will need a brief CV in ord er to elaborate a consultation contract . Once the contract is executed, we would like to invite you for a phone conference which will include few medical AbbVie colleagues . Looking fo rward to hearing from you . With best regards, Fernando Tatsch FERNANDOTATSCH, MD, MBA Therapeutic Area Head - HCV/ RSV Global Medical Affairs 25W 102 08 I 1 N Waukegan Rd I North Chicago, IL 60064 OFFICE-t (b)(6) I CELLJ (b) (6)1 1EMAIL________ (b '"'~"'c= abbvie.com This commu nicati on may contain info rmation t hat is prop rietary, confident ial, or exemp t from disclosure. If you are not the inten ded recipient , please note that any oth er dissemination, distr ibut ion, use or copying of t his comm unication is strictly proh ibited. Anyone who receives th is message in error should not ify the sender immediate ly by telephone or by return e-mail and de lete it from his or her compute r. NIH-002386 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :50 :25 +0000 Conrad, Patricia (NIH/NIAID) [El Billet , Courtney (NIH/NIAID) [El;Barasch, Kimbe rly (NIH/NIAID) [C] FW: 60 Minu tes/ Coronav irus From: Date: To: Cc: Subject: If we can fit this in next week depending on what is hitt ing t he fan, I will do it. -------------~~ (b)(6)> From: Conrad, Patricia (NIH/NIAID) [E] Date: Friday, January 31, 2020 7:53 PM To: Fauci, Anthony (NIH/NIAID) [El "i._______ Subject: Fwd: 60 Minute s / Coronavirus Cb> _<.... ~> Pis advise Sent from my iPhone Begin forwarded message: From: "Stover, Kathy (NIH/NIA ID) [EJ" ______ Date: January 31, 2020 at 7 :52 :16 PM EST Cb _H_j;j> -------..,,.,..,(b:-::-)_<= ,..> To: "Conrad, Patricia (NIH/NIAID) (E]"~=====,::~ Cc: "Billet, Courtney (NIH/NIAID) [E]" [E)" (b) (6) -------- (b)(6)>, "Routh, Jennifer (NIH/NIAID) Subject: Fwd: 60 Minute s/ Coronavirus Hi Patty, See below. Would Dr. Fauci want to meet with this 60 Mins produce r, or shall I suggest an alternative? Note, this isn't for on-camera - -it's background fo r a potential story . Sent from my iPhone Begin forwarded message: From: " Lieberm an, Marc E." Date: January 31, 2020 at 5:57 :24 PM EST (b)(6) Subject: 60 Minutes / Coronavirus Hi, I am a producer at 60 Minutes researching a possible story about t he coronavirus outbreak. The effort to find a vaccine strikes me as interest ing and I wonder if we m ight be to chat about it. I am going to be in th e DC area next week. Would you have time for a brief meeting either Wednesday morning o r Tuesday? Than ks in advance fo r your help . Best, NIH-002387 Marc Lieberman Marc Lieberman I Producer I 60 Minutes m lp@cbsnews .com I w: 212-975-6385 NIH-002388 c: ----- (b)(6) I Fauci, Anthony (NIH/NIAIO) [El Sat, 1 Feb 2020 18:4 5:22 +0000 Folkers, Greg (NIH/NIAID) [E] RE:ASF: Dan Chertow invitation From: Date: To: Subject: No prob lem with Dan doing this. -------- From: Folkers, Greg (NIH/NIAID) [E] Date: Friday, January 31, 2020 10:05 PM To: Billet, Courtney (NIH/NIAID) [E]-------=- CbH > (b'""' )(= Fauci, Anthony (NIH/NIAID) [E] (b)(6)> Cc: Marston, Hilary (NIH/N IAID) [E] (b)(6)>; -~---~==:::!......:___....:...~ (b)(6); Stover, Kathy (NIH/NIAID) [E] ~ Conrad, Patricia (NIH/N IAID) [E] (b)(6) Routh, Jennifer (NIH/NIAID) [E] (b)(6) Subject: RE:ASF: Dan Chertow invitation Agree with Courtney Dan is a good speaker and would represent nih we ll -------- (b)(6)> From: Billet, Courtney (NIH/NIAID) [El Date: Friday, January 31, 2020 9:40 PM To: Fauci, Anthony (NIH/NIAID) [El CbH6J1> Cc: Marston, Hilary (NIH/NIAID) [El (b)( Folkers, Greg (NIH/NIAID) [El CbH ; Conrad, Patricia (NIH/NIAID) [E] (b)(6J>; Stover, Kathy ':":"'."~:-'."'."":'"".":'":-:-::"::-===:::!:..--~~ (NIH/NIAID) [El Cb)( >; Routh, Jennifer (NIH/N IAID)[E] CbH6)> Subject: ASF: Dan Chertow invitation ------= = Dan Chertow has been asked to speak at this event, which has some rather high profile participants and media attendance. He would like to do it. ■ Do you agree? (b)(6)> From: "Cohen, Justin (NIH/CC/OD) [E]" Date: Friday, January 31, 2020 at 4:43:08 PM To: "Myles, Renate (NIH/OD) [E]" CbH ·, "Fine, Amanda (NIH/OD) [E]" CbH6)>, "Routh, Jennifer (NIH/NIAIO) [E]" Cb)( >, "Billet, Courtney (b)(6) (NIH/NIAID) [El" -:":"".":"'.-:-:-::-:-:--:-::-:~==---:;;;-;-,-,= Cc: "Burklow, John (NIH/OD) [El" (b)(6) , "Wojtowicz, Emma (NIH/OD) [El" -------- ------~= -------- NIH-002389 "NIAID NEWS {NIH/NIAID)" ---------Subject: FW: coronavirus speaking opportunity (b)(6), Obvious ly given the current environment (not to ment ion some of the names involved in the event), want to make sure I'm in lockstep with you all from square one . How would you like me to proceed with the request below? The event is open to the public/ press. From: Chertow, Daniel (NIH/CC/CCMD) (El Date: Thursday, January 30, 2020 6:16 PM -------------~= To: Cohen, Justin {NIH/CC/OD) [El (b)( -------(bH > (b)(6)> >; Freimuth, Molly {NIH/CC/OC) [El Cc: Suffredini, Anthony (NIH/CC/CCMD) [El_______ Cb _H_6)>; Masur, Henry (NIH/CC/CCMD) [El (b)(6) Subject: FW: Hudson Institute speaking request Dear Justin, I am checking back in with you regarding the below invitation to speak. I would like to participate in this if possible. Please confirm that you have received my email. Thank you. Sincerely, Dan From: "Asha M. George" Date: Thursday , January 30, 2020 at 6:09 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" Subject: Re: Hudson Institu te speaking request ------~~ CbH6J> Dear Dan, Sorry, we have changed something slightly. Instead of taking questions directly from the audience, we will obtain questions from the audience via email while the first part of the event occurs, curate them, and then have them available for Senator Lieberman to ask them of the speakers. Asha Asha M. George, DrPH Executive Director NIH-002390 BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Tw itter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint From: Asha M. George Date: Thursday, January 30, 2020 6:02 PM To: Chertow, Daniel (NIH/CC/CCMD) [E]-------= (b"H=6) Subject: Re: Hudson Institute speaking request Dear Dan, Here are some more specifics regarding the event we will holding at Hudson Institute on novel coronavirus. The meeting will be on February 10th , from 2:00 - 3:30 pm in the Stern Conference Center at Hudson Institu te, which is located at 1201 Pennsyl vania Avenue, NW, 4th floor, Washington, DC 20004. We also have the executive conference room reserv ed from 1:30 pm on. Please plan to arrive around then, so that you can talk with Senator Lieberman and the other speakers before the event starts at 2:00 pm. Just ask the receptionist to direct you where to go. Here are the speakers: • Forme r Senator Joe Lieberman , co-chair, Bipartisan Commission on Biodefense • Dr. Julie Gerberding, Executive Vice President & Chief Patient Officer, Strategic Communications, Global Public Policy and Population Health , Merck; former Director, Centers for Disease Control and Prevention • Dr. Billy Karesh, ex officio , Bipartisan Commission on Biodefense ; Executive VP, EcoHealth Alliance • The Honorable Tim Morrison, Senior Fellow, Hudson Institute ; former Deputy Assistant to President Trump for National Security; former Special Assistant to the President and Senior Director for Weapons of Mass Destruction and Biodefense • Mr. Eric Brown, Senior Fellow, Hudson Institute NIH-002391 • Dr. Daniel S. Chertow (CAPT - US Public Health Service) , Head, Emerging Pathogens Section , Critical Care Medicine Department , Clinical Center & Laboratory of lmmunoregulation , National Institute of Allergy and Infectious Diseases , National Institutes of Health (invited) The setting will be relatively informal. Scooter Libby will first introduce Senator Lieberman . Then Senator Lieberman will make a short opening statement, and look to Billy to set the stage and talk about the zoonotic nature of the disease , associated disease management considerations , etc., in about 5 minutes. The Senator will then ask each of the other speakers to say a few words from their perspectives . Afte r that, Senator Lieberman will ask some questions of the group, allowing you all to answer and converse. All of this should take about 45 minutes. Then we will allow the audience to ask questions . We are planning for Senator Lieberman to moderate the discussion and take questions from the audience , but if for some reason he cannot do so, then Billy Karesh will. I hope you will be able to make it, Dan. Let me know if you have any questions (and if you will be able to make it, of course) and I look forward to seeing you on February 10th. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org Linkedln I Twitter I Facebook I lnstagram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyondthe blueprint NIH-002392 From: Chertow, Daniel (NIH/CC/CCMD) [E] ______ Cb _>_C6) _> Date: Tuesday, January 28, 2020 7 :18 PM To: Asha M. George Subject: Re: Hudson Institute speaking request Dear Asha, Given that this is a publi c/press event, I wi ll require additional clearance from my organizat ion in order to participate. I will reach out to them now and get back to you. Thank you . Dan From: "Asha M. George" Date: Tuesday , January 28, 2020 at 7:15 PM To: "Chertow, Daniel (NIH/CC/CCMD) [E]" (b)( > ------~~ Subject: Re: Hudson Institute speaking request Dear Dan , Thank you! The meeting will be held on February 1oth . We are still trying to nail down a time with Senator Lieberman and Governor Ridge, so I will get back to you about that as soon as possible , hopefully tomorrow. The meeting will be open to the public and to the press, but Hudson Institute is a think tank , so it's never a negative or rowdy crowd. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202.974.2416 biodefensecommission.org NIH-002393 Linkedln I Twitter I Facebook I lnstagram i~M. BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint ________ ... From: Chertow, Daniel (NIH/CC/CCMD) (E) Date: Tuesday, January 28, 2020 5:53 PM (b)(6) To: Asha M . George Subject: Re: Hudson Institute speaking request Dear Asha, I am available Feb 10th or 13th and would be happy to present to the group. Please clarify who will be in attendance and if the event is open or closed to press/public as this would requi re add itional clearance on my end . Thank you. Sincerely, Dan Daniel S. Chertow, MD, MPH, FCCM, FIDSA CAPT, United States Public Health Service Head, Emerging Pathogens Section Critical Care Medicine Department , NIH Clinical Center & Laboratory of lmmunoregulation, NIAID From: "Asha M . Ge org e " Date: M onday , January 27, 2020 at 6:09 PM NIH-002394 (b)( 6) To: "Chertow, Daniel (NIH/CC/CCMD)[E]" Subject: Hudson Inst itute speak ing request Dear Dr. Chertow, I am the Executive Director of the Bipartisan Commission on Biodefense , co-chaired by former Senator Joe Lieberman and Governor Tom Ridge . Our fiscal sponsor is Hudson Institute, one of the think tanks here in DC. Hudson lnstitute's chair of the board of trustees (Sarah May Stern) has asked Hudson Institute to run a 90 minu te mee ting on the novel coronavirus situa tion. Hudson has asked us to help them pull a brief meet ing together in short order . Considering your experience on the ground dealing with other outbreaks , Hudson Institute invites you to speak at this event. In addition to one of Hudson lnstitute's China experts , we are also seeing whether Senator Lieberman and Governor Ridge are available to speak. Here are the dates they are a looking at: February 6, February 1O, and February 13. Cou ld you let me know if you are available and if so , when on those dates? Thank you for your consideration, Dan. I look forward to hearing from you soon. Asha Asha M. George, DrPH Executive Director BIPARTISAN COMMISSION ON BIODEFENSE 202 .974.2416 biodefensecommission .org Linkedln I Tw itter I Facebook I lnsta gram I~~ BIPARTISAN COMMISSION ONBIODEFENSE Beyond the blueprint NIH-002395 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:43:31 +0000 Kristian G. Andersen RE: FW: Science: Mining coronavirus genomes for clues to the outbreak's origins Thanks, Kristian. Talk soon on the call. -------------- (b) (6)1> From: Kristian G. Andersen Date: Friday, January 31, 2020 10:32 PM To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) ,;....:._..:__......:...:....:.!:::::=~~-----Cc: Jeremy Farrar (b) ( > Subject: Re: FW: Science: Mining coronavirus genomes for clues to the outbreak 's origins .----..-.= Hi Tony, Thanks for shari ng. Yes, I saw th is ear lier today and both Eddie and myself are actually quoted in it . It's a great article, but the problem is that our phylogenetic analyses aren't able to answer whether the sequences are unusual at indivi dual residues, except if they are completely of f. On a phylogeneti c t ree the virus looks totally normal and the close clustering with bats suggest that bats serve as the reservoir . The unusual fea tures of the virus make up a really small part of the genome (<0.1%) so one has to look really closely at all the sequences to see that some of the features (potentially) look engineered. We have a good team lined up to look very critically at this, so w e should know much more at the end of the weekend . I should mention that after discussions earlier today, Eddie, Bob, Mike, and myself all find the genome inconsistent wit h expectations from evolutionary theory . But w e have t o look at this much more closely and th ere are still further analyses to be done, so tho se opinions could still change. Best, Kristian -------- On Fri, Jan 31, 2020 at 18:47 Fauci, Anthony (NIH/NIA ID) [E) (b)(6)> wrote: Jeremy/Kristian: This just came ou t today. discuss ion. You may have seen it. If not, it is of interest to the cu r rent Best, Tony From: Folkers, Greg (NIH/NIA ID) [E)_______ _ >_C6) Cb _ Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genome s for clues t o t he outbreak 's origins NIH-002396 As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaact ttcgatctc ttgtagatct ... That string of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhelming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Init iat ive on Sharing All Influenza Data database. These viral genomes are being intensely studied to try to understand the origin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this new ly discovered virus physically looks like . how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human -to -human spread," says Trevor Bedford, a bioinformatics specialist at t he University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The vira l sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstrain.org , preprint servers like bioRxiv, and even in peer-rev iewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the wor ld to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) NIH-002397 When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-wh ich are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat vi rus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARScoronavirus has a similarly close relationship to bat v iruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. According to Bedford 's analysis, the bat corona viru s sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On next strain.org , a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are int eract ive-by dragging a computer mouse over them, it's easy to see the differences and similar ities between the sequences.) -- ~ ...... .-.11 ... -.-·--. ,_ -- ~ 111(4::-1 -u , ,_. Ill ----------..... .....----- ~..J~ ----------r 0 00 om '"" '"" -~- .._... _-_.... _1........... c::=.~,:::::::• fl lJ OJ• Ot • Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two v iruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by comb ining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronav iruse s. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, similarly has a link to bat viruses. But studies have built a compelling case it jumped to humans from camels. And the phylogenetic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002398 TGEV 100 100 100 100 100 97 MlnkCoV FerretCoV Bat CoV CDP HE15 Scotophilus bat CoV 512 PEDV Bat CoV HKU10 Mlnlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bal NL63-related CoV Human CoV 229E SADS-CoV Rhinolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus Rat CoV HKU24 Human CoV HKU1 100 Human MERS-CoV Came l MERS-CoV Pfplstra/lus bat CoV HKUS Tytonycteris Bat CoV HKU4 Hedge hog CoV 100 SARS-CoV BJ0 1 Civet SARS-CoV S23 Bat SARSr -CoV WIV1 Bat SARSr-CoV SHC01 4 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 go Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 Bat SARSr-CoV BM48-31 100 100 100 97 100 BetaCoV/Wuha n/WIV0S /2 019 B ataCo V /Wuha n/WIV02 /201 9 BetaCoV/Wuha n/WIV0-4/2 019 8e t aCoVrNuha nlWIV06 / 20 19 BctaCoV/Wuha n/WIV07 /201 9 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang 2013 Rousettusbat CoV HKU 9 Bat CoV GCCDC1 IBV 0. 1 The longer a virus circulates in a human popu lations, the more time it has to develop mutations that differentia te strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very rece ntly. But it remains a mystery wh ich animal spread the virus to humans . "There' s a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseases who studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spread ing 2019-nCoV, but w hether it was the origin of the outbreak remains uncertain . Many of the initially confirmed 2019-nCoV cases-27 of the fi rst 41 in one repor t , 26 of 47 in another -wer e connected to the Wuhan market, but up to 45%, including the earliest handful, were not . This raises the possibi lity that the initial jump into people happened elsewhe re. NIH-002399 Accord ing t o Xinhua. the state-run news agency. "environmental sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is whe re wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the first group to publicly release a 2019-nCoV sequence . "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus ." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and determine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanation for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmitted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodi ly samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth All iance In t he absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifica lly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substantial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however. pillor ied !!Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rted on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, wh ich is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the inst itute predate this outbreak. Nature ran a story in 2017 about it building a new blosafety level 4 lab and Included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeat edly happened NIH-002400 with lab workers handling SARSin Beiji ng. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculation that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsiderthat the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longtime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszaksays. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group will be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bat s in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth All iance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of wh ich fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province . "We cannot assume that just because this virus from Yunnan has high sequence identity with the new one that that's the origin," Daszaksays, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in: • Asia/ Pacific NIH-002401 • Healt h • Coro navi rus doi:10 .11 26/science.abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Tw it te r Disclaimer : Any third-part y material in this email bas been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessaril y represent my views nor those of NIAID, NIH, HHS, or the U.S. government. NIH-002402 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:39:50 +0000 Billet, Courtney (NIH/NIAID) [E] FW: Possible cure medically to the new coronav irus,corona virus,from wuhan china. Attachme nts: medicalcure.docx NIA ID inquiries, p lease From: andrew igla (b)(6)> Se nt: Saturday, February 1, 2020 2:22 AM To: Fauci, Anthony (NIH/NIAID) [E]______ (b '"'~..-. (6) => Subject: Fw: Possible cure medically to the new coronavirus,corona virus,from wuhan china . read t hi s emai l. From: andrew igla (b)(6) Se nt: Tuesday, 28 January 2020 6:36 PM To: secretary@hhs .gov Subject: Fw: Possible cure medically to the new coronavirus,corona vi rus,from wuhan china . From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 9:10 PM To: secretary@ hhs.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china . For secreta ry Azar th is emai l. From: andrew igla (b)(6)> Date: Sunday, 26 January 2020 8:59 PM To: secretary@ HHS.gov Subject: Possible cure medically to the new coronavirus,corona virus,from wuhan china. NIH-002403 From: andrew igla Date: Sunday,26 January2020 1:25 (b)(6) This ema il is to be sent to the doctors treating medically patients in hospitals involving the new coronavirus,corona virus, from wuhan china.This email contains the possible medical cure to the new coronavirus,corona virus,from wuhan china.URGENT.Discovered from an australian friend of the amer ican people,andrew igla. This email is about orally tak ing zovirax and ciproxin together for one day. Orally taking ciproxin,inhibiting gyrase,orally taking zovi rax,inhibit ing viral DNA polymerase, together at the same time, stops viral dna moving medically curing viruses in host cells stoping duplica ting viral infected cells and stoping a virus invading new uninfected cells. Attached document contains possible medical cure to new corona virus from wuhan in china to help you win over this virus. Dear professor and politic an, My name is andrew igla and work as a research science person in dengue virus and anaconda sea snake virus. Attached is a business document for you. Thanks, Andrew igla. me lbourne australia. NIH-002404 From: Date: To: Subject: Attachments : Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18:35:10 +0000 Cassetti, Cristina (NIH/NIAID) [E] FW: 2019-nCoV Aminopeptidase N inhibitors and Coronaviruses-LANCET2003.pdf Pleasehandle. From: Kontoyiannis,Dimitrios P_________ Date: Saturday, February 1, 2020 1:28 PM ------~~ To: Fauci, Anthony (NIH/NIAID) [E] Subject: FW: 2019-nCoV Cb _H_6)> _______ _. (b)(6)> Dear Dr Fauci, I enjoyed your recen t editorial in JAMA re Coronaviruses Although the viral disease is not an area of my expertise, you might want to take a look at a hypothesis we had proposed, long ago (back in the era of SARS), re the potential of immune-modulating Coronavirus infection natural history with blockage of aminopeptidase N. I am not aware of any studies whether aminopeptidase is a receptor of China 2019nCoV, though. Sincerely DPK Dimitrios P. Kontoyiannis. MD. ScD. PhD (Hon). FACP. F/DSA. FECMM. FAAM. FAAAS Texas 4000 Distinguished Endowed Professor For Cancer Research Deputy Head , Division of Internal Medicine The University of Texas MD Anderson Cancer Center ECMM Diamond Excellence in Mycology Center/www .ecmm .info Adj Professor Baylor College of Medicine Adj Professor UT School of Public Health Adj Professor University of Houston The informat ion contained in this e-mail message may be privileged, confidentia l, and/or protected from disclosure. This e-ma il message may contain protected health information (PHI); dissemination of PHI should comply with applicable federa l and state laws. If you are not the intended recipient, or an authorized representative of the intended recipient, any further review, disclosure, use, disseminat ion, distribution, or copying of this message or any attachment (or the information contained therein) is strictly prohibited. If you think that you have received this e-mail message in error, please not ify the sender by return e-mail and delete all references to it and its contents from your systems. NIH-002405 From: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 18 :34 :43 +0000 Tabak, Lawrence (NIH/OD) [E) FW: Teleconference Coro navirus sequence comparison[l].pdf Date: To: Subject: Attachments : FYI From: Jeremy Farrar (b)(6)> Date: Saturday, February 1, 2020 1:13 PM To: Fauci, Anthony (NIH/NIAID) [E] ------~= (b) ( >; Patrick Vallance (b)(6) ------ (b)(6); Marion Koopmans Cc: Drosten , Christian (b)(6)>; R.A.M. Fouchier (b)( ; Edward Holmes (b)(6) Andrew Rambaut -----~--======~~:;;---:--:-Krist ian G. Andersen Paul Schreier (b)( ======-;- (b)( ; CbH ; Ferguson, Mike .___________ (b~)(~ (b)(6) (b)(6) _ ; ; Collins, Francis {NIH/OD) [E) Subject: Re: Teleconference Kristen and Eddie have shared this and will ta lk through it on the call. Thank you. Hope it will help frame the discussions. From: Jeremy Farrar (b)(6) Date: Saturday, 1 February 2020 at 15:34 1st February (2nd Feb for Eddie) Information and discussion is shared in total confidence and not to be shared until agreement on next steps. Dial in details attached. Please mute phones . I will be on email throughout - email Paul or I Paul if any problems If you cannot make it, I will phone you afterwards to update . One Hour 6am Sydney 8pm CET NIH-002406 7pm GMT 2pm EST 11am PST (Hope I have the times right!) Thank you for the series of calls and for agreeing to jo in this call. Agenda • Introduction , focus and desired outcomes - JF • Summary - KA • Comments - EH • Q&A-AII • Summary and next steps - JF Kristian Anderson Bob Garry - I have not been able to contact Bob. Please forward if you can. Christian Drosten Tony Fauci Mike Ferguson Ron Fouchier Eddie Holmes Marion Koopmans Stefan Pohlmann Andrew Rambaut Paul Schreier Patrick Vallance NIH-002407 From: Date: Fauci,Anthony (NIH/NIAIO)[E) Sat, 1 Feb 2020 18:23:07 +0000 To: Kay Johnson RE: thank you for continuing leadership Subject: Kay: Thank you for your kind note. Best regards, Tony Much appreciated. -----------------=-,-=, From: KayJohnson Date: Saturday, February 1, 2020 9:15 AM (b)(6) -------- To: Fauci, Anthony (NIH/NIAID) [E) (b)(6) Subject: thank you for continuing leadership Dear Dr. Fauci - We met long ago when I was a young health policy staff person at the Children's Defense Fund and you gave a talk on HIV/AIDS at the annual CDF conference around 1984-86. When I served on the National Vaccine Advisory Committee (NVAC) during the 1990-9 1 measles epidemic and helped to write the measles whitepaper, I had other occasions to hear your insights. Since that time, I have frequently heard you on the PBSNewsHour and NPR, I see your perspectives in JAMA and other journals. (For examp le, this week I heard NPR piece and read JAMA opinion piece on coronavirus.) In every instance, I am struck again by how clearly you articulate the science, the issues for public concern, and options for our nation 's response. While I've worked with many public health leaders and watched others in the media over the past 35 years of my Maternal and Child Health public policy career, I believe no one is better at communications than you. It is in some ways a thank less job. I am writing to say that your continuing leadership and dedication to our nation's health is deeply appreciated by me and millions of others. Best regards, Kay Kay Johnson President, Johnson Group Consult ing, Inc. voice: Cb)(6) fax: 802-482-3008 Email: ---------- (b)(6) NIH-002408 From: Date: To: Cc: Subject: Attachments : Fauci,Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:56:42 +0000 Cassetti, Cristina (NIH/NIAID) [El Conrad, Patricia (NIH/NIAID) [El FW: article from IIT/India on Coronovirus 20200130.2019-nCOVsequence paper.927871vl.full.pdf Please handle. From: WRB Gmail CbH > Date: Saturday, February 1, 2020 10:27 AM To: Fauci, Anthony (NIH/NIAID) [E]------~= Cc: Hong Cai (b)(6) Subject: article from IIT/India on Coronovirus (b)(6) Hi Tony, I hope you are coping with the chaos around coronavirus. I am (b)(6)1 but still active, currently chair of Mesa Biotech, (b)(4) (b) (4) No doubt you have seen, but in case not, I am sending a copy. Hopefully someone at NIH is trying methodology . to replicate this study or to find problems with the ir With best wishes, Bill NIH-002409 William R. Brody (b)(6) l ohns Hopkins University Salk Institute for Biological Studies NIH-0024 10 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 17:54:38 +0000 Greg Folkers (b)(6) Conrad, Patricia (NIH/NIAID) [E] FW: POLITICO: New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak We should make a similar slide for upcoming talks. --------- (b)(6) From: Folkers, Greg (NIH/N IAID) [E) Se nt: Saturday, February 1, 2020 10:44 AM Subject: POLITICO:New FDA chief plans for 'the most serious scenarios' of coronavirus outbreak EXCLUSIVE New FDAchief plansfor 'the most seriousscenarios'of coronavirusoutbreak CBD, drug prices, safety - plus Wuhan coronavi rus - make for a crowded agenda for Stephen Hahn. The FDA for years has mostly stayed out of the debate around drug prices I Jacquelyn Martin, File/ AP Photo By SARAH OWERMOHLE and SARAH KARLIN-SMITH 01/31/2020 04:54 PM EST Updated: 01/31/2020 05:28 PM EST New FDA commissioner Stephen Hahn faced a jam-packed agenda: opioids , CBD, vaping, and how to let states safely import drugs. Then the Wuhan coronavirus broke out. The virus was declared a public health emergency by HHSjust a few hours after Hahn's exclusive interview with POLITICOFriday. That kicks the agency into overdrive in multiple roles - helping speed vaccine, drug and diagnostic test development while also trying to avoid shortages of drugs and devices the United States needs that are made in China. Advertisement Hahn said there have not been any reports yet of disruption of the supply chain or shortages, but the agency is looking ahead and planning for "what could potentially be the most serious of scenarios." As of now FDA inspections in China are being conducted on a case-by-case basis. NIH-002411 "We are taking on an individual -by-individual basis what's the regulatory need for anything in China ... versus what are the personnel risks associated," he said. Monitoring the the situation in China could soon get trickier as the State Department expands mandatory evacuation from affected areas of the country. The coronavirus also broke out in an election year when President Donald Trump wants to deliver on his promise to bring down drug prices - not traditionally the province of the FDA, a regulatory agency designed to focus on safety and efficacy . "If my patients couldn't get access to something because of cost - that was a real problem for me as a doctor . Now I'm on the other end of that, but what can we do to make sure that that pipeline flows in the best way possible?" said Hahn, 60, an oncolog ist, researcher and Washington newcomer. Hahn was confi rmed as commissioner on Dec. 18, the night before the administrat ion announced its plan to let states import cheaper medicines from Canada - an approach that prior FDA commissioners opposed over fears it would jeopardize the safety of the drug supply . Trump has endorsed letting states such as Florida do this. NIH-002412 WHOdeclares global health emergency 9,826 The novel coronavirusthat first infected people in Wuhan.China. has spread to more than 20 other countries, with Russia and the U.K. report ing their first cases of the viral pneumonia on Jan . 31. 7,818 6.065 2019-nCoVis a coronav1rus. a type of virus similarto the comm°"cold,SARS 4,593 artdMERS.Ir is spreadby close contact with peoplewho are inleaed.One study suggestsmen might be more susceptible to che virus than women. Cases confirmed by WHO ASOFJAH.31 2,798 2,01G 1,320 581 282 314 6 Jan. 20 6 21 ------17 25 Cont, ed deaths "' 170 213 56 BO 106 132 - 23 24 25 26 27 28 29 30 31 Sour~s WHO.SouthChinaMorningPo-it.newsrf!pons By PattttSOn Clark. POLITICO Pro OataP(llnl Patterson Clark/POLITICO Pro DataPoint "There is a compe lling reason that the American peop le want us to cons ider this and so we're go ing to have to figure th is one out and balance both of those issues," Hahn said, referring to safety and affordability. NIH-0024 13 The FDAfor years has mostly stayed out of the debate around drug prices; the agency doesn't regulate the cost of medicines or health insurance coverage. But Hahn talked up FDA's role in getting prices down by approving more generics, acknowledging that "the American people are expecting us to do more." Trump has touted the FDA's record on boosting competition via generic approvals . As FDA works on finalizing the importation rule , Hahn said the agency will be open to addressing criticism that states can't save money bringing in drugs from Canada if the pathway is too burdensome. But he stressed safety is tantamount. "Our primary concern is the protection of the drug supply," he said. Hahn said he has also talked with CMS Administrator Seema Verma about addressing costs of new brand-name products that are approved with limited data sets, similar to the way CMS decides to cover some medical devices. That approach - known as coverage with evidence development - let s CMS cover a new prod uct on the condition that manufacturers keep providing data. FDA has not done that, but new medicines are increasingly being approved on smaller clinical trials without hard data on clinical benefits - and can come with six-figure price tags. As an academic, Hahn had co-written an editorial suggesting that payments for newly approved radiation oncology devices cou ld be linked t o olde r products unt il enough evidence builds up to show that the new products are superior. Only then would manufacturers have more pricing leeway . "It's a CMS call about coverage with evidence development, but I do think in this world where we are concerned, and rightfully so, about the cost of medicine and health et cetera, that we should be looking at all avenues to approach that, " he told POLITICO. Over the last few years, some cr it ics have said t he FDA is overcorrecting and moving too quickly to approve drugs without adequate evidence. But Hahn did not indicate he would put the brakes on. "At the end of the day there is this balance between the gold standard and being efficient and getting th ings in people's hands I'm totally confident in the agency's ability to do that." Hahn must balance all that while leading the FDA's response t o t he Wuhan crisis, which has heightened some lawmakers' concern about U.S. reliance on Chinese drug manufacturing after incidents of contamination with carcinogens. "We have to be concerned about the supply chain to make sure that we have enough of what we need if there are any potential outbreaks here," Rep. Susan Brooks (R-lnd .) said after a closed-door briefing Thursday for Energy and Commerce committee members with top health officials . The fact that China manufactures much of the protective medical gear used in U.S. hospitals and clinics "should cause us to be reexamining what we're doing in China versus what should be brought back to this country." she said. Outside of the coronavirus, a host of thorny regulatory issues await Hahn. Industry and lawmakers have pressed for a clear FDAframework on selling cannabidiol, the popular hemp and marijuana byproduct decriminalized by the 2018 farm bill - and since sold as medicine, dietary supplements and infused in food, cosmetics and skincare products . "You cannot walk down the street without seeing the products " but there is a dearth of solid data on how safe and effective CBD actually is, said Hahn. Those CBD challenges have fueled larger discussions about how to better regulate the vast dietary supplement market, where manufacturers often push legal boundaries by making unverified claims about how herbal or homeopathic products can help peop le. "It will be something else next," said Hahn. We don't want to overstep our boun ds but we want to make sure that safe and effective products are in the hands of people." Disclaimer: Any third-party material in this email has been shared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy/veracity . It does not necessarily represent my views nor those ofNIAID , NIH , HHS, or the U.S. government . NIH-002414 From: Date: To: Subject: Fauci, Anthony (NIH/N IAID) [El Sat, 1 Feb 2020 17:51 :31 +0000 Auchincloss, Hugh (NIH/NIA ID) [El RE: Continu ed OK. Stay tuned. -----Orig inal M essage ----From: Auchinclos s, Hugh (NlH/N IAJD) [E]...________ Date: Saturday, Febrnary 1, 2020 11:47 AM To: Fauci, Anthony (NIH/NIAID) [E] (b)( > Subject: Con tinued _~ (b _ <..,. -----~~ The paper you sent me says the experim ents were perfonn ed before the ga in of fun ction pause but have since been rev iewe d and appr oved by NIH. Not sure what that means since Emily is sure that no Coronavirus work bas gone through the P3 framewo rk. She will try to detem 1ine if we have any distant ties to this work abroad. Sent from my iPad NIH-0024 15 From: Fauci, Anthony (NIH/NIAID) [El Sat, 1 Feb 2020 17:32:40 +0000 To: Cassetti, Cristina (NIH/NIAID) [El Subject: FW: 2019 Novel Coronavirus:NanoViric ides Confirms It Has Been Working On A Treatment For The Novel Wuhan Coronavirus Date: Pea se handle. ---<-Origi11alMessage----From: Amit Gup ta (b) ( > S~nt: Saturcl..ay,Fe bruary I, 2020 12:23 PM To: Fauci , Anthony (NIH/NIAJD) [E] ,,;:;;...-------~~ --------,;..,.,-,, = (b)(6) > Subject: 20 19 Nove l Coronavirus:NanoVir icides Con:finn s Tt Has Bee n Working On A Treahne nt For The Novel Wuhan Coronavims Dear Dr. Fauci. Wondering if you have see the corona virus treatmen t news. I know you were involved in Ebola previously. You are a great Scientist and Do ctor. Coronavirus update: WHO says prepare for local corona virus outbreaks in other countries; What do you think about this treatment. Regards, Amit SHEL TON, CONNECT JCUT -- Thur sday, January 30, 2020 -- Nano Viricides, Joe. (NYSE Amer.: NNVC) (the "Company"), a global leader in the deve lopment of highly effective antiviral therapies based on a novel nanomedicin es platform , is confirm ing public disclosures in articles by various industry journals and other articles , that it is working on developing a treatmen t for the novel coronavirus 20 l 9-nCoV , or the Wuhan coronavirus. "We have already initiated a program for developing a treatment for the 2019-nCOV ," said Anil R. D iwan , PhD, President and Executive Chairman of the Company , adding, "Our platform technology enables possib ly the most rap id pathway for new drug deve lopment against viral diseases. Of course , we wi II need suppo rt from governmen tal and international agencies suc h as the US CDC, WHO , and Chinese CDC to successfu lly develop these treatments, and, if developed , to get them to the patients in the fastest possible time. At this time, the Co mpany does no t have a col labora tion with any of these agencies, and we have not been contacted by any of these ent ities or asked to develop a treat ment for this virus. We had collaborations with the CDC and USAMRII D in the past. The Company intends to pursue a relevant collaboration for testing of our drug candidates soo n." The new 20 19-nCoV is known to be closely related to the SARS-CoV of 2002-2003 epidemic. In fact it has been shown to use the same cell surface receptor as SARS -Co V, nam ely ACE2 . "We hav e already found some lead candida te ligands in our chemical librar y tha t can bind to the SARS-CoV spike pro tein in the same fash ion as it binds to the cognate recep tor , ACE2, using molecu lar modeling tools ," explained Dr. Diwan, add ing , "We believe this means we may already be significantly ahead in developing a po tential treatm ent for the new Wuhan virus. " While the Company commissions synthesi s of the anti-nCo V nanoviricide drug candidates for test ing , some of which are already in our hands , in pa rallel, the Company has also started preparing for testing of the candidates in cell cultures against certain known BSL2 coronaviruses , including ones that use the ACE2 receptor. Less threatfu l viruses in the same family that use the same receptor can serve as valid test viruses for screening our broad-spectrum antiviral drug candidates . The Company ha, its own BSL2-certified virology laboratory at its Shelton campus where NIH-0024 16 it intends to perform this testing. The Company has its own cGMP -capable drug manufa ctu ring facility. This highly custom izab le facility can be employed to produce severa l thousand doses of drugs per batch for treating coronavirus patients , if the Company's drug successfu lly transitions to obtai ning an explo ratory treatment approval for use in patients . The Company's platform technology has already proven that it can result in safe drugs. The Company 's first INDready clinica l drug candidate , namely NV-HHV- 101, has successfu lly undergon e a standard battery of Safety and Toxicological testing , as previously disclosed by the Company in press releases and SEC fil ings. The Company is building on its previous work against coronaviruses . The Company's technology relies on copying the human cell-surface receptor to which the virus binds, and making small chemicals that are called "ligands" that will bind to the virus in the same fashion as the cognate receptor. These ligands are chemically attached to a nanomice lle, to create a nanov iricide®. It is antic ipated that when a virus comes in contact with the nanoviricidc, not only woul d it land on the nanov iricide surface , binding to the copious number of ligands presented there, but it would also get entrapped because the nanomicelle polymer would turn around and fuse with the virus lipid envelo p, harnessing a well known biophysica l phenomenon. "It is like a 'Venus-Fly- Trap' for the virus, " explained Dr. Diwan . The Company focuses on developing broad-spectrum ligands and, thereby, broad-spectrum nanoviiicides , copying the specific human cellu lar receptor. No matter how much a virus mutates, it lands on the same cell surface receptor, and binds in the same fashion. Thus , it is highly unli.kely that a virus mjght escape a nanoviricide against it, in spite of mutations. Tn2014 , the Company had worked on developing antiviral treatment s against MERS-CoV , and coronaviruses in general. lt bad deve loped potential candidates for testing in anima l models. The MERS-CoV threat was eclipsed by the Ebola epide mic of 2015 . The Compa ny developed viable drug cand idates against Ebola in a rapid response time of a few weeks and sent them for testing to USAMRJID. These initial candidates showed significan t activity. The Company believes that another cycle of optimization would have resulted in a candidate ready for animal testing under the criteria estab lished by USAMRTJD then. During these previous ciises , the Company did not have the modern labs, the cGMP drug manufacturing faci lity or the BSL2 virology testing facility, all of which were commi ssioned after 2015 at its modern campus in Shelton, CT. The Company is preparing an IND application for its first clinica l drug candidate to go into human clinical trials. This drug candidate, NV -HHV -101, is a skin cream with the treatment of shingles rash as its first indicat ion . It has shown broad-spectrum activ ity against HSY- I (cause of "cold sores"), HSV-2 (cause of "gerutal ulcers"), and VZV (the varice lla-zoster virus, that causes chickenpox in children and immune-compromised humans , and shing les in adults). NV-HHV-101 has already gone through standard battery of safety-toxico logical testing, which provides confidence that our platform is capable of creating safe drugs. The Company has its own cGMP-c apable drug manufacturing facility where it intends to produce the drugs for clinical supply. The Company's top priority remruns working on its first IND application for NV- HHV-l01. The Company intends to so licit interest and financing from gove rnment agencies in order to accelerate its work on the coronaviruses . The market size for the treatment of shing les is estimated at approximately one billion dollars by various estimates. These estimates take into account the Shingrix ® vaccine as well as existing vaccines. About 500,000 to 1million cases of shing les occur in the USA alone every year. The market size for our immediate target drugs in the HerpeCid e™ program is variously estimate d at billions to tens of billions of dollars. The Company believes that its dermal topica l cream for the treatment of shing les rash will be NIH-002417 its first drug heading into clinical trials. The Company believes that additional topical treatment candidates in the HerpeCide™ program, namely , HSY-I "cold sores" treatment, and HSV-2 "genital ulcers" treatment are expected to follow the shing les candidate into IND-enabling development and then into human clinical trials . These additional candidates are based on NV-HHV-101, thereby maximizing return on investments and shareholder value. The Company develops its class of drugs , that we call nanoviricides ®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus . The nanoviricide ® technology enables direct attacks at multip le points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at on ly a maximum of two attachment points per antibody. In add ition, the nanovi ricide technology also simultaneously enables attacking the rapid intracellular reproduction of the virus by incorporating one or more active pharmaceutical ingredients (APls) within the core of the nanovi1icide. The nanoviricide technology is the only technology in the world, to the best of our knowledge , that is capable of both (a) attacking extracellular vims, thereby breaking the reinfection cycle, and simu ltaneously (b) disrupting intracellular production of the virus, thereby enabling complete control of a virus infection. About NanoYiricides NanoYiricides, Inc.(www.nanoviricides.com)is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide ® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHY-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis , HIN l swine flu, H5Nl bird flu, seasonal Influenza, HlV , Hepatitis C, Rabies , Dengue fever, and Ebola virus , among others. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to dtugs developed in these areas from TheraCour Pharma, lnc. This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actua l events could differ materially and substantially from those projected hereiD and depend on a number of factors. Ce11ainstatements in this release , and other written or oral statements made by NanoViricides , Inc. are "forward -looking statements" within the meaning of Section 27 A of the Securities Act of 1933 and Section 2 l E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors whicb are, in some cases , beyond the Company's control and which could, and likely will, materially affect actual results , levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these fo1ward-looking statements, even if new infonnation becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include , but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful cotmnercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration . IND application refers to "lnvestigational New Drug" application. CMC refers to "Chemistry, MaDufacture, and Controls". Contact: NanoViricides , Inc. info@nanoviricides.com NIH-002418 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 13 :19:06 +0000 To: Tabak, Lawrence (NIH/OD) [E) FW: IMPORTANT Barie, Shi et al - Natu re medicine - SARS Gain of function.pdf Subj ect : At tac hment s: Here it is Anthony S. Fauci, MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive , MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301) 496-4409 E-mail: (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information. It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives. NIH-002421 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:43:22 +0000 To: Marston, Hilary (NIH/NIAID) [E] Cc: Conrad, Patricia (NIH/NIAID) [E] Subject: FW: 2019 novel Coronavirus Global research and innovation forum : towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachment s: Global Research Forum dv2AMHR AM.PDF From: Date: We need to talk about this later in the day .. I am on Conference calls now. Apparently I w ill call you later. Soumya is reaching out separate ly t o other people in NIA ID. From: SWAMI NATHAN, Soumya ---------- Se nt: Saturday, February 1, 2020 7:19 AM To: Fauci, Anthony (NIH/NIAID) [E)______ (b)(6) """ (b"""" )(=6) Subject: 2019 novel Coronavirus Global research and innovat ion forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research prior ities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each t hematic area forward. Several thematic areas will be considered at the meeting, namely: virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward. This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners. The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself . As the head of an agency that would play an impor tant role in addressing this new viral outbreak, either by undertaking or funding research, or both, I ta ke great pleasure in inviting you to this meeting. I apologize for the short not ice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation . Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)(6) and (b)(6) in your response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002422 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002423 Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:32:57 +0000 To: 00~ Subject: FW: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ Attachme nts: Global Research Forum dv2AMHR AM.PDF From: Date: Cliff: Whom should I nominate? See ye llow highlight Tony From: SWAMI NATHAN, Soumya Subject: 2019 novel Coronavirus Global research and innovation forum: towards a research roadmap Feb 11-12, 2020 Geneva WHO HQ DearTony I am delighted to inform you that WHO is organizing a global research partners forum on February 11th and 12th in Geneva, to discuss research priorities related to the novel Corona virus . The expected outcome is a research roadmap with clearly defined priorit ies and a governance framework to take each thematic area forward. Several thematic areas will be considered at the meeting , namely : virus, diagnostics; natural history and transmission; clinical; therapeutics; vaccines; ethics; regulatory science; animal health; data/samples analysis and sharing and; social sciences. We believe that this meeting will be critical in consensus building on the most important research questions, as well as in building global partnerships and collaborations to take this work forward . This meeting is being organized in partnership with GLOPIDRand is being supported by the Bill and Melinda Gates foundation, DFID, Wellcome Trust and several other partners . The secretariat within WHO is the R&D blueprint, co-chaired by Dr Mike Ryan and myself. As the head of an agency that would play an important role in addressing this new viral outbreak, either by undertaking or funding research, or both, I take great pleasure in inviting you to this meeting . I apologize for the short notice, but you will understand that we have had to plan this in the past few days, keeping in mind the evolving situation. Kindly let me know if you (or your nominee) will be able to attend and if you need any support from us. Please copy (b)( and (b)(6linyour response. With best wishes, Soumya Dr Soumya Swaminathan NIH-002424 Chief Scient ist PS: Sorry if this is a duplication - just want to make sure the key people receive the invite . Sorry about the short notice! NIH-002425 From: Date: To: Cc: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:36 +0000 Auchincloss, Hugh (NIH/NIAID) [C] ---------- (b)( 6) (b)(6) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins As per my prior e-mail. --------- (b)(6) From: Folkers, Greg (NIH/NIA ID) [El Date: Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaactttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world. Scientists are publicly sharing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Init iative on Sharing All Influe nza Data database . These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered virus physically look s like, how it' s changing, and how it might be stopped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in NIH-002426 Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their ow n diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, reported on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionsh ip to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) --- ~ .... 10 -'<.__ _ ,. ,_, -- ~ F======:: ~:s::;: =-: -u , ,a NIH-002427 Bedford's analyses of RaTG13 and 2019 -nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the d ifference in nucleotides bet ween the viruses with the presumed ra te s of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019 -nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But studies have built a compelling case it jumped to huma ns from camels. And the phylogene ti c tree from Sh i's bioRxiv paper (below) makes the camel-MER$ link easy to see. ,...-----TGEV ,---,..__ __ Mink CoV FerretCoV .----,----._____ .----..---._ ___ Bat CoV HKU10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 ~----.______ Human CoV NL63 Bat NL63-related CoV Human CoV 229E 100 ---~~ 100 SAOS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 ,...___ Murine hepatitis virus ---R ,____ at CoV HKU24 Huma n CoV HKU1 100 ,,__ -1 Human MERS-CoV Camel MERS-CoV ,...._ __ Plpistrellus bat CoV HKUS ,....___ TytonycterisBat CoV HKU4 100 Hedgehog CoV too SARS -CoV BJ0 1 Civet SARS-CoV SZ3 Bat SARSr -GoV WIV1 too 90 97 .__ _____ .______ .----100 ------IBV Bat CoV COPHE15 Scotophifus bat CoV 512 PEDV Bat SARSr-CoV SHC014 Bat SARSr-CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-CoV ZC45 Bat SARSr-CoV HKU3-1 ,....___ Bat SARSr-CoV BM48-31 BetaCoV/Wuhan/W IV0S/2019 1oo BetaCoV/Wuhan/WIV02 /2019 BetaCoV/Wuhan/WIV04/2019 BetaCoV/Wuh.in/WlV06 / 2019 100 BctaCoV/Wuhan/W1V07 /2019 Bat CoV RaTG13 Bat Hp BetaCoV Zhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 0.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and give n that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently. But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detec ted in bats and the virus now isolated in humans," says Vince nt Munster, a virologist at the NIH-002428 U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one repo rt, 26 of 47 in anot her -were connected to the Wuhan market, but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces . Or an infected animal trader could have transmitted the virus to different people at different markets . Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife anima l reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was disto rt ed on social med ia to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of NIH-002429 Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a st o ry in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers Universi ty, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionar y distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that t he 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszakof the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out : This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems hum ans can't resist controversy and these myths, yet it's staring us right in t he face. There' s this incredible diversity of viruses in wildlife and we've just scratched the surface . Within that diversity, there will be some t hat can infect peop le and within that group wi ll be some that cause il lness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Allia nce Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one t hat th at's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . "I expect that once we've sampled and sampled and sampled across southern China and central China that we' re going to find many other viruses and some of them will be closer [to 2019-nCoV] ." NIH-002430 It's not just a "curious interest" to figure out what sparked the current outbreak, Daszak says. "If we don't find the origin, it could still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is still out on what the real origins of this are." Posted in; • Asia/Pacifi c • Health • Coronaviru s doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science. • Email Jon • Twitt er Disclaimer : Any third-party material in this email has been sbared for internal use under fair use provisions of U.S. copyright law, without further verification of its accuracy /veracity . It does not necessarily repre sent my views nor those of NlAID , NIH , HHS , or the U.S. government. NIH-002431 From: Date: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 12:29:0 1 +0000 To: Cc: Auchincloss, Hugh (NIH/NIAID) [C] Subject: Attachments: IMPORTANT ----------- (b)(6) (b)(6) Barie, Shi et al - Nature medicine - SARSGain of function.pdf Hugh: It is essential that we speak th is AM. Keep your cell phone on. I have a conference call at 7:45 AM with Azar. It like ly will be over at 8:45 AM. Readthis paper as well as the e-mail that I will forward to you now. You will have tasks today that must be done. Thanks, Tony Anthony S. Fauci , MD Director National Institute of Allergy and Infectious Diseases Building 31, Room 7A-03 31 Center Drive, MSC 2520 National Institutes of Health Bethesda , MD 20892-2520 Phone : (b)(6) FAX: (301 496-4409 E-mail : (b)(6) The information in this e-mail and any of its attachments is confidential and may contain sensitive information . It should not be used by anyone who is not the original intended recipient. If you have received this e-mail in error please inform the sender and delete it from your mailbox or any other storage devices . The National Institute of Allergy and Infectious Diseases (NIAID) shall not accept liability for any statements made that are the sender's own and not expressly made on behalf of the NIAID by one of its representatives . NIH-002432 From: Date: To: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:48:59 +0000 Kadlec, Robert (OS/ASPR/IO) (b)(6) Cc: Subject: FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Bob: This just came out today. Gives a balanced view. Best, Tony From: Folkers, Greg (NIH/NIA ID) [E) (b)(6)> Se nt : Friday, January 31, 2020 8:43 PM Subject: Science: Mining coronavirus genomes for clues to the outbreak's origins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Alliance Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt tataccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overwhe lming China and frightening the entire world . Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients - 53 at last count in the Global Initiative on Shari ng All Influenza Data database. These v iral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discovered vi rus physically looks like, how it' s changing, and how it might be stopped . NIH-002433 "One of the biggest takeaway messages [from the viral sequences] is that there was a single introduction into humans and then human-to -human spread," says Trevor Bedford, a bioinformatics specialist at the University of Washington, Seattle. The role of Huanan Seafood Wholesale Market in Wuhan, China, in spreading 2019-nCoV remains murky, though such sequencing, combined with sampling the market's environment for the presence of the virus, is clarifying that it indeed had an important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that hold the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on virological.org. nextstrain.org . preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science's news stories on the outbreak can be found here.) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known coronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repo rted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% similar to a bat virus and had 79.5% similarity to the coronavirus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides. That's one reason why many scient ists suspect there's an "intermediary" host species-or several-between bats and 2019-nCoV. Accord ing to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstra in.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The trees are inte ractive -by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) NIH-002434 . ~ -- ..... ...... ..,.., ··•- .... ,..., A ■- ,_ ,.._,__,, -II r:===~~s -- -_., =, •ou .., ------------------c= om ---'-'-"' =~ I=-= -----------1 =.•M.""l'"l_..l __ ..-·~· ...., __ - Cl ,u .. tf.C-,Xt1 014 au Bedford's analyses of RaTG13 and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS),another human disease caused by a coronavirus, simi larly has a link to bat viruses . But studies have built a compelling case it jumped to humans from camels. And the phylogene ti c tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. NIH-002435 .~---TGE .....--- ,____ V M ink CoV FerretCoV .....---- .----L----PE ~--100 ,_____ .------.______ '-------,-,~ --- 100 ---R ---- 100 ~- DV Bat CoV HKU 10 Minlopterus bat CoV 1 Miniopterus bat CoV HKU8 Human CoV NL63 Bat NL63-related CoV Human CoV 229 E SADS-CoV Rhfnolophus bat CoV HKU2 Human CoV OC43 Murine hepatitis virus at CoV HKU24 Huma n CoV HKU1 100-1Human MER S-CoV __ Camel MER S-CoV Plplstrell us bat CoV HKUS --Tytonycteris Bat CoV HKU4 Hedgehog CoV SARS-CoV 8J01 Civet SARS-CoV SZ3 Bat SARSr -CoV wrv1 Bat SARSr -CoV SHC01 4 Bat SARSr-CoV LYR a11 Ba1SARSr-CoVRf1 to Bat SARSr-COV ZC4 5 Bat SARSr-CoV HKU3- 1 --Bal SARSr-CoV BM48-31 BetaCoV/Wuhan/WlV0S /2019 100 Beh1CoV/Wuhan/WIV02 / 2019 BetaCo V/Wuhan/W IV0-4/ 2019 IQO BetaCo V/Wuhan/W IV06/ 2019 100 BeuCoV/Wuhan/W IV07 / 2019 Bat CoV RaTG13 97 ,__ _____ Bat Hp BetaCoV Zhejiang 2013 ____ ,,...... ___ Rousettusbat CoV HKU9 100 100 91 100 ------ISV Bat CoV CDPHE15 Sootophifus bat CoV 512 Bat CoV GCCOC 1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2O19-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into humans very recently . But it remains a mystery which animal spread the virus to humans . "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Institute of Allergy and Infectious Diseaseswho studies coronaviruses in bats, camels, and others species. Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the out break remains uncertain. Many of the initially confirmed 2019-nCoV cases- 27 of the first 41 in one report , 26 of 47 in anothe r-were connected to the Wuhan market, but up to 45%, including the earliest handful , were not. This raises the possibility that the initial jump into people happened elsewhere . NIH-002436 According to Xinhua, the state-run news agency, "environmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold. "The positive tests from the wet market are hugely important/' says Edward Holmes, an evolutionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficult to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered humans is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It would be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how man zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about the outbreak's origin, theories thrive, and some have been scientifical ly shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pilloried it . Conspiracy theories also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distort ed on social media to suggest that they were spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biologist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab workers handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with NIH-002437 dangerous pathogens, also in 2015 crit icized an exper iment in which modifications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans. Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13- the virus held in the Wuhan virology institute - and 2019-nCoV, arguing that the mutation rate may have been different as it passed through different hosts before humans. Ebright tells 5ciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science,but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face. There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses . EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses , about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered. "I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV]." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak dies, there could be a cont inued spillover that's really hard to stop. But the jury is st ill out on what the real origins of this are." Posted in: • Asia/ Pacific • Health NIH-002438 • Coronav irus doi :10.1126/science.abb1256 Jon Cohen Jon is a staff writer f or Science. • Email Jon • Twitter Disclaimer: Any third -party material in this email has been shared for ittternal use unde1· fair use provisions of U.S. copyright law , without fm·ther verification of its accuracy /veracity . It does not necessarily repre sent my views nor those ofNTATD, NTH, HHS , or the U.S. government. NIH-00243 9 From: Date: To: Subject: Fauci, Anthony (NIH/NIAIO) [E) Sat, 1 Feb 2020 02:46:21 +0000 Mascola, John (NIH/VRC) [E) FW: Science: Mining coronavirus genomes for clues to the outbreak's or igins Here is the Jon Cohen article. From: Folkers, Greg (NIH/NIAID) [E] (b)(6) Date: Friday, January 31, 2020 8:43 PM Subject: Science: M ining coronavirus genomes for clues to the outbreak's or igins As part of a long-running effort to see what viruses bats harbor, researchers in China collect one from a cave in Guandong. EcoHealth Allia nce Mining coronavirus genomes for clues to the outbreak's origins By Jon CohenJan. 31, 2020, 6:20 PM attaaaggtt ta taccttcc caggtaacaa accaaccaac tttcgatctc ttgtagatct ... That str ing of apparent gibberish is anything but: It 's a snippet of a DNA sequence from the viral pathogen, dubbed 2019 novel coronavirus (2019-nCoV), that is overw helmi ng China and frightening the entire world. Scientists are publicly shar ing an ever-growing number of full sequences of the virus from patients-53 at last count in the Global Initiative on Sharing All Influ enza Data database. These viral genomes are being intensely studied to try to understand the or igin of 2019-nCoV and how it fits on the family tree of related viruses found in bats and other species. They have also given glimpses into what this newly discove red vi rus physically looks like, how it's changing, and how it might be st opped . "One of the biggest takeaway messages [from the viral sequences] is that there was a single intr oduction into humans and then human-to-human spread," says Trevor Bedford, a bioinformatics specialist at the Univers ity of Washington, Seattle . The role of Huanan Seafood Wholesale Ma rket in Wuhan , China, in spreading 2019-nCoV remains murky, though such sequencing, combined w ith sampling the market's environment for the presence of the virus, is clarifying that it indeed had an NIH-002440 important early role in amplifying the outbreak. The viral sequences, most researchers say, also knock down the idea the pathogen came from a virology institute in Wuhan. In all, 2019-nCoV has nearly 29,000 nucleotides bases that ho ld the genetic instruction book to produce the virus. Although it's one of the many viruses whose genes are in the form of RNA, scientists convert the viral genome into DNA, with bases known in shorthand as A, T, C, and G, to make it easier to study. Many analyses of 2019-nCoV's sequences have already appeared on viro logical.org, nextstra in.o rg, preprint servers like bioRxiv, and even in peer-reviewed journals. The sharing of the sequences by Chinese researchers allowed public health labs around the world to develop their own diagnostics for the virus, which now has been found in 18 other countries. (Science'snews stories on the outbreak can be found here. ) When the first 2019-nCoV sequence became available, researchers placed it on a family tree of known co ronaviruses-which are abundant and infect many species-and found that it was most closely related to relatives found in bats. A team led by Shi Zheng-Li, a coronavirus specialist at the Wuhan Institute of Virology, repor ted on 23 January on bioRxiv that 2019-nCoV's sequence was 96.2% simi lar to a bat virus and had 79.5% similarity to the coronav irus that causes severe acute respiratory syndrome (SARS),a disease whose initial outbreak was also in China more than 15 years ago. But the SARS coronavirus has a similarly close relat ionship to bat viruses, and sequence data make a powerful case that it jumped into people from a coronavirus in civets that differed from human SARSviruses by as few as 10 nucleotides . That's one reason why many scientists suspect there's an "intermedia ry" host species-or several-between bats and 2019-nCoV. According to Bedford's analysis, the bat coronavirus sequence that Shi Zheng-Li's team highlighted, dubbed RaTG13,differs from 2019-nCoV by nearly 1100 nucleotides. On nextstrain.org, a site he cofounded, Bedford has created coronavirus family trees (example below) that include bat, civet, SARS, and 2019-nCoV sequences. (The t rees are inte ract ive-by dragging a computer mouse over them, it's easy to see the differences and similarities between the sequences.) -----= __ _ ,_,,. ~ ~ ~==:: ~;s;:. ,uu , ID Bedford's analyses of RaTG13and 2019-nCoV suggest that the two viruses shared a common ancestor 25 to 65 years ago, an estimate he arrived at by combining the difference in nucleotides between the NIH-002441 viruses with the presumed rates of mutation in other coronaviruses. So it likely took decades for RaTG13-like viruses to mutate into 2019-nCoV. Middle East respiratory syndrome (MERS), another human disease caused by a coronavirus, simi larly has a link to bat viruses. But stud ies have built a compelling case it jumped to humans from camels. And the phylogene tic tree from Shi's bioRxiv paper (below) makes the camel-MERS link easy to see. ,...-----TGEV ,---- M ink CoV '----ferret .----,----.__ ___ .----..---100 Bat CoV HKU10 Miniopterus bat CoV 1 Miniopterusbat CoV HKU8 Human CoV NL63 ...---- Bat NL63-re lated CoV ---- ...._____ ,____ CoV Bat CoV COPHE15 Scotophifusbat CoV 512 PEDV Human CoV 229E ___,..,,,.. SADS-CoV Rhinolophusbat CoV HKU2 Human CoV OC43 Murine hepatitis virus .____ Rat CoV HKU24 ,____ Human CoV HKU1 ,__•oo~ Human MERS-CoV Camel MERS-CoV '---Pfplstre/lL JSbat CoV HKU5 100 ,____ Tytonycteris Bat CoV HKU4 ....___ Hedgehog CoV 100 tooSARS-CoVBJ01 100 CivetSARS-CoVSZ3 Bat SARSr-CoV WIV1 Bat SARSr-CoVSHC014 Bat SARSr -CoV LYRa11 Bat SARSr-CoV Rf1 Bat SARSr-COV ZC45 Bat SARSr-CoV HKU3-1 90 97 .____ 100 97 .______ ,___ ___ .----- ._______ ,av 100 Bat SARSr-CoVBM48-31 BetaCoV/Wuha nlWIVOS/2O19 100 BetaCoV/Wuha nlWIVO2/2O19 BetaCoV/Wuha n/WIV04/2 019 BetaCoV/Wuha n/WIVO6f2O19 100 BetaCoVIWuha n/WIV07/2019 Bat CoV RaTG13 BatHp BetaCoVZhejiang2013 Rousettusbat CoV HKU9 Bat CoV GCCOC1 Q.1 The longer a virus circulates in a human populat ions, the more time it has to develop mutations that differentiate strains in infected people, and given that the 2019-nCoV sequences analyzed to date differ from each other by seven nucleotides at most, this suggests it jumped into hum ans very recently . But it rema ins a mystery which animal spread the virus to humans. "There's a very large gray area between viruses detected in bats and the virus now isolated in humans," says Vincent Munster, a virologist at the U.S. National Inst itute of Allergy and Infectio us Diseases who studies coronaviruses in bats, camels, and others species. NIH-002442 Strong evidence suggests the marketplace played an early role in spreading 2019-nCoV, but whether it was the or igin of the outbreak remains uncertain. Many of the initially confirmed 2019-nCoV cases-2 7 of the first 41 in one repor t, 26 of 47 in another - were connected to the Wuhan market , but up to 45%, including the earliest handful , were not . This raises the possibility that the initial jump into people happened elsewhere . According to Xinhua, the state-run news agency, "en vironmenta l sampling" of the Wuhan seafood market has found evidence of 2019-nCoV. Of the 585 samples tested, 33 were positive for 2019-nCoV and all were in the huge market's western portion, which is where wildlife were sold . "The positive tests from the wet market are hugely important," says Edward Holmes, an evolut ionary biologist at the University of Sydney who collaborated with the fi rst group to publicly release a 2019-nCoV sequence. "Such a high rate of positive tests would strongly imply that animals in the market played a key role in the emergence of the virus." Yet there have been no preprints or official scientific reports on the sampling, so it's not clear which, if any, animals tested positive. "Until you consistently isolate the virus out of a single species, it's really, really difficu lt to try and dete rmine what the natural host is," says Kristian Andersen, an evolutionary biologist at Scripps Research. One possible explanat ion for the confusion about where the virus first entered huma ns is if there was a batch of recently infected animals sold at different marketplaces. Or an infected animal trader could have transmi tted the virus to different people at different markets. Or, Bedford suggests, those early cases could have been infected by viruses that didn't easily transmit and sputtered out. "It woul d be hugely helpful to have just a sequence or two from the marketplace [environmental sampling] that could illuminate how many zoonoses occurred and when they occurred," Bedford says. A research group sent fecal and other bodily samples from bats they trapped in caves to the Wuhan Institute of Virology to search for coronaviruses. EcoHealth Alliance In the absence of clear conclusions about t he outbreak's origin, theories thrive, and some have been scientifically shaky. A sequence analysis led by Wei Ji of Peking University and published on line by the Journal of Medical Virology received substant ial press coverage when it suggested that "snake is the most probable wildlife animal reservoir for the 2019-nCoV." Sequence specialists, however, pillo ried it. Conspiracy theor ies also abound. A CBCNews report about the Canadian government deporting Chinese scientists who worked in a Winnipeg lab that studies dangerous pathogens was distorted on social med ia to suggest that they we re spies who had smuggled out coronaviruses. The Wuhan Institute of Virology, which is the premier lab in China that studies bat and human coronaviruses, has also come NIH-002443 under fi re. "Experts debunk fringe theory linking China's coronavirus to weapons research," read a headline on a story in The Washington Post that focused on the facility. Concerns about the institute predate this outbreak. Nature ran a story in 2017 about it building a new biosafety level 4 lab and included molecular biolog ist Richard Ebright of Rutgers University, Piscataway, expressing concerns about accidental infections, which he noted repeatedly happened with lab worke rs handling SARSin Beijing. Ebright, who has a long history of raising red flags about studies with dangerous pathogens, also in 2015 crit icized an experiment in which modif ications were made to a SARS-likevirus circulating in Chinese bats to see whether it had the potential to cause disease in humans . Earlier this week, Ebright quest ioned t he accuracy of Bedford's calculat ion that there are at least 25 years of evolutionary distance between RaTG13-the virus held in the Wuhan virology institute-and 2019-nCoV, arguing that t he mutation rate may have been different as it passed through different hosts before humans. Ebright tells Sciencelnsider that the 2019-nCoV data are "consistent with entry into the human population as a natural accident." Shi did not reply to emails from Science, but her longt ime collaborator, disease ecologist Peter Daszak of the EcoHealth Alliance, dismissed Ebright's conjecture. "Every time there's an emerging disease, a new virus, the same story comes out: This is a spillover or the release of an agent or a bioengineered virus," Daszak says. "It's just a shame. It seems humans can't resist controversy and these myths, yet it's staring us right in the face . There's this incredible diversity of viruses in wildlife and we've just scratched the surface. Within that diversity, there will be some that can infect people and within that group wi ll be some that cause illness." A team of researchers from the Wuhan Institute of Virology and the EcoHealth Alliance have trapped bats in caves all over China, like this one in Guangdong, to sample them for coronaviruses. EcoHealth Alliance Daszak and Shi's group have for 8 years been trapping bats in caves around China to sample their feces and blood for viruses. He says they have sampled more than 10,000 bats and 2000 other species. They have found some 500 novel coronaviruses, about 50 of which fall relatively close to the SARSvirus on the family tree, including RaTG13-it was fished out of a bat fecal sample they collected in 2013 from a cave in Moglang in Yunnan province. "We cannot assume that just because th is virus from Yunnan has high sequence identity with the new one that that's the origin," Daszak says, noting that only a tiny fraction of coronaviruses that infect bats have been discovered . " I expect that once we've sampled and sampled and sampled across southern China and central China that we're going to find many other viruses and some of them will be closer [to 2019-nCoV)." It's not just a "curious interest" to figure out what sparked the current outbreak , Daszak says. "If we don't find the origin, it cou ld still be a raging infection at a farm somewhere, and once this outbreak NIH-002444 dies, there could be a cont inued spillover that's really hard to stop. But t he jury is st ill out on what the real origins of this are." Posted in: • Asia/Pacific • Health • Coronavirus doi:10.1126/science .abb1256 Jon Cohen Jon is a staff writer for Science . • Email Jon • Twitter Disclaim er: Any third-party material in this email has been shared for internal use under fair use prov isions of U.S. copyright law, without further verification of its accurac y/veracity. It does not necessa rily repre sent my views nor those of NlAlD, Nill, HHS, or the U.S. government. NIH-002445